#ExOne

[imdoingjustgr8]

my take on sonexe summarized in 4 frames

sorry if it's obnoxiously dark on anyone's device there was no going back after i exported everything and deleted the mdp file (because i decided to do the shading on medibang for whatever reason)

also have an extra bonus side doodle

he may be infatuated with him, but even exe has his boundaries

[mindblowingscience]

Although you may not appreciate them, or have even heard of them, throughout your body, countless microscopic machines called spliceosomes are hard at work. As you sit and read, they are faithfully and rapidly putting back together the broken information in your genes by removing sequences called "introns" so that your messenger RNAs can make the correct proteins needed by your cells. Introns are perhaps one of our genome's biggest mysteries. They are DNA sequences that interrupt the sensible protein-coding information in your genes, and need to be "spliced out." The human genome has hundreds of thousands of introns, about 7 or 8 per gene, and each is removed by a specialized RNA protein complex called the "spliceosome" that cuts out all the introns and splices together the remaining coding sequences, called exons. How this system of broken genes and the spliceosome evolved in our genomes is not known.

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[huariqueje]

The Jetty - Randall Exon , 2022.

American , b. 1956 -

Oil on panel , 60 × 68 in. 152.4 × 172.7 cm .

[redbunnydragon]

This fucken summer heat is trying to end me.

[txttletale]

what's up with alexis kennedy (wrt the 'he is many things, many of them bad')?

he dated two of his employees while he was the CEO of failbetter games which is by all accounts pretty fucked up

[politicaldilfs]

Nebraska Governor DILFs

Ben Nelson, Bob Kerrey, Frank B. Morrison, Norbert Tiemann, Pete Ricketts, Arthur J. Weaver, Charles Thone, Charles W. Bryan, Dwight Griswold, J. James Exon, Robert Leroy Cochran, Dave Heineman, Dwight W. Burney, Jim Pillen, Victor Emanuel Anderson, Mike Johanns, Ralph G. Brooks, Val Peterson

[babayaganoush]

They are Alaskan sea birds from 1989

staying with my father and my teenage brother occasionally has been very enlightening actually i need to think about it positively

[imdoingjustgr8]

generic lowishbutkindadidtakeastupidamountof-effort meme bandwagoning post

[huariqueje]

Morning View, Beach House  - Randall Exon , 2012.

American , b. 1956 -

Oil on linen , 28 × 48 in.

[the-corset-witch]

Unfortunately, I too started pressing buttons in desperation because I'd been told this before, and alas, nothing muted them, so unfortunately it does not seem to be a failsafe, and I didn't want to get back in my car just to get out because it was so gross and slushy (and I didn't want to get my car's insides extra slushy just to get back in/out)

Maybe it's my most 'ad hating comie' trait, but I don't want to have to go out of my way to get back in my car just because they need to advertise with AV equipment while I pump gas.

I just got described as an "ad hating commie" by someone because I said a minute of youtube ads is unpleasant. fully spent 5 minutes arguing and defending youtube ads. insane stuff

[biology-geology-beaches-india]

TSRNOSS, page 209.

[creativeera]

The Duchenne Muscular Dystrophy Treatment Market is Trending Towards Gene Therapy

The Duchenne Muscular Dystrophy Treatment market is experiencing promising trends through gene therapy. Duchenne muscular dystrophy (DMD) is a rare genetic disorder characterized by progressive muscle degeneration and weakness. The condition is caused due to the lack of dystrophin protein which helps keep muscle cells intact. The standard of care currently involves corticosteroids to delay the progression. However, gene therapy is emerging as a breakthrough in finding a cure. The Duchenne muscular dystrophy treatment market comprises products for replacing the missing dystrophin gene or gene therapy. Exon skipping medications and gene therapies aim to restore functional dystrophin production. These advanced treatments address the underlying cause of DMD by repairing the genetic mutation. The gene therapy products offer hope of a one-time administration with long-lasting effects against this currently incurable disease. The global Duchenne muscular dystrophy treatment market is estimated to be valued at US$ 1.5 billion in 2024 and is expected to exhibit a CAGR of 47% over the forecast period 2024-2034.

Growing research activities towards finding a cure and rising investment in novel therapeutics are fueling the market growth. Key Takeaways Key players operating in the Duchenne muscular dystrophy treatment market are Sarepta Therapeutics, Pfizer, PTC Therapeutics, Solid Biosciences etc. Sarepta Therapeutics dominates with its exon skipping drug Exondys 51 as the first approved medication. The Duchenne Muscular Dystrophy Treatment Market Trend is growing significantly owing rising diagnosis rates and growing medical needs of the patient population. According to Parent Project Muscular Dystrophy, around 1 in every 3,500 male children is born with DMD. Growing patient advocacy is also driving awareness and screening. The market is witnessing expansion into new geographical regions with ongoing clinical trials of gene therapies. Players are evaluating therapies across regions like Europe, Asia, and other developed markets. Positive data is also attracting strategic collaborations and investments towards commercialization. Market Key Trends One of the major trends in the Duchenne Muscular Dystrophy treatment market is the promising pipeline of gene therapies. Several gene therapies are in late stage development addressing critical unmet needs. Select candidates have shown efficacy in animal studies and early human trials. Pfizer's gene therapy candidate is anticipated to be a blockbuster on approval. Its widespread adoption could potentially capture a sizable market share, driving the gene therapy trend further.

Porter's Analysis Threat of new entrants: High barrier to entry due to expensive R&D and clinical trials required.

Bargaining power of buyers: Limited bargaining power of patients suffering from rare disease.

Bargaining power of suppliers: Strong bargaining power of suppliers due to limited treatment options.

Threat of new substitutes: Low threat due to no effective treatment substitutes currently available.

Competitive rivalry: High competitive rivalry among existing players to develop innovative treatments. Geographical Regions North America region holds the major share of the global Duchenne muscular dystrophy treatment market in terms of value, owing to higher adoption of high-priced therapies. The U.S. accounts for the largest share of the North America as well as global market. Asia Pacific region is expected to witness the fastest growth during the forecast period majorly driven by increasing healthcare expenditure, large patient pool and rising awareness about treatment options in emerging countries such as China and India.

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[edimexon]

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❇️ وزن هر لنگه:۲۷۰ گرم

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[homophyte]

most of the time i feel pretty competent when i read papers but occasionally i am left the pathetic brainless jocktype going " Uh in English Four Eyes "

[tarragonthedragon]

honestly most of these headlines come from 17 rounds of "can we get this past legal" followed by a final topping of "the editor rewrote it from scratch on proofs" if you're at a national

Love how shit the media is.