#@Kyprolis

[daisyloretta]

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[lenalidomideprice]

Comprehensive Overview of Multiple Myeloma Treatment Methods: A Doctor's Perspective

Multiple myeloma is a challenging cancer that affects plasma cells in the bone marrow. Early detection and treatment are critical to managing the disease. With various multiple myeloma treatment methods available today, we can significantly improve patient outcomes. This post will explore the most common treatments, including chemotherapy, targeted therapy, immunotherapy, and drugs like lenalidomide.

Standard Treatment Methods for Multiple Myeloma

Chemotherapy

Chemotherapy is a cornerstone of multiple myeloma treatment. It works by killing fast-growing cells, including cancerous plasma cells. Common chemotherapy drugs used include melphalan and cyclophosphamide.

Chemotherapy is often combined with other treatments to increase effectiveness. For example, it can be used before a stem cell transplant or in cases of aggressive disease. Despite its benefits, chemotherapy can cause side effects such as fatigue, nausea, and infections due to a weakened immune system.

Targeted Therapy

Targeted therapy specifically attacks proteins or genes that are key to cancer cell growth. Unlike chemotherapy, which affects both healthy and cancerous cells, targeted therapy is more precise.

Drugs like bortezomib (Velcade), carfilzomib (Kyprolis), and ixazomib (Ninlaro) are common targeted treatments for multiple myeloma. They work by inhibiting proteasomes, causing cancer cells to die.

Targeted therapies are often combined with other drugs, such as lenalidomide, to boost their effectiveness. These drugs generally have fewer side effects than traditional chemotherapy, although they can cause neuropathy or gastrointestinal issues.

Immunotherapy

Immunotherapy is one of the most promising advancements in multiple myeloma treatment. This therapy uses the body's immune system to target and destroy cancer cells.

Lenalidomide (Revlimid) and pomalidomide (Pomalyst) are immunomodulatory drugs widely used in newly diagnosed and relapsed cases of multiple myeloma. Lenalidomide enhances the immune system’s ability to kill cancer cells and prevents the formation of blood vessels that feed tumors.

Lenalidomide is often combined with dexamethasone, a corticosteroid that enhances its anti-cancer effects. However, side effects such as low blood counts, fatigue, and an increased risk of blood clots need to be managed closely.

Stem Cell Transplantation: A Curative Option

For some patients, stem cell transplantation offers a more curative approach. Two types of transplants are used: autologous (using the patient’s own stem cells) and allogeneic (using donor stem cells).

In many cases, patients undergo autologous stem cell transplantation after high-dose chemotherapy to reduce cancer cells. Although it can lead to long-term remission, there are risks, including infection and relapse.

Lenalidomide: A Pillar in Multiple Myeloma Therapy

Lenalidomide is a central drug in the treatment of multiple myeloma. It is used in both newly diagnosed and relapsed patients, often combined with other treatments like bortezomib and dexamethasone.

One of the biggest challenges with lenalidomide is its cost. The price of lenalidomide can range from $10,000 to $20,000 per month, making it difficult for many patients to afford. Despite its cost, lenalidomide is highly effective at prolonging progression-free survival and improving quality of life.

The Cost of Multiple Myeloma Treatment

The cost of multiple myeloma treatments can be significant. Beyond lenalidomide, other drugs like bortezomib and carfilzomib are also expensive, especially when used in combination therapy.

In addition to drug costs, patients often incur expenses related to stem cell transplants, hospital stays, and supportive care like blood transfusions or bone-strengthening medications. Navigating insurance coverage and patient assistance programs is crucial for many patients to manage these costs effectively.

Conclusion: The Future of Multiple Myeloma Treatment

The treatment landscape for multiple myeloma is evolving rapidly, with exciting new therapies like CAR-T cell therapy and bispecific antibodies showing promise in clinical trials. As a doctor, I am hopeful that these advancements will lead to even better outcomes for my patients.

For now, the key to successful treatment lies in a personalized approach that balances the effectiveness of therapies like chemotherapy, immunotherapy, and targeted therapy with their side effects and costs. Despite the high cost of medications like lenalidomide, their benefits make them invaluable tools in the fight against multiple myeloma.

Frequently Asked Questions (FAQ)

1. What is the most common treatment for multiple myeloma?

The most common treatment for multiple myeloma typically includes chemotherapy, targeted therapy, and immunotherapy. A combination of these treatments is often used depending on the patient’s stage and health. Stem cell transplants are also considered for patients eligible for more aggressive treatments.

2. How does lenalidomide help in treating multiple myeloma?

Lenalidomide (Revlimid) is an immunomodulatory drug that helps enhance the immune system’s ability to attack cancer cells. It also prevents the growth of blood vessels that tumors need to survive. Lenalidomide is often combined with other medications like dexamethasone and is used in both newly diagnosed and relapsed patients.

3. Why is the cost of multiple myeloma treatment so high?

The cost of multiple myeloma treatments can be high due to the expense of newer therapies like lenalidomide, bortezomib, and carfilzomib. Additionally, stem cell transplants, hospital stays, and supportive care add to the overall cost. Many patients rely on insurance and assistance programs to help cover these expenses.

[priteshwemarketresearch]

Carfilzomib Market Statistics, Segment, Trends and Forecast to 2034

TheCarfilzomib Market: Trends, Opportunities, and Future Outlook

Introduction

In recent years, the pharmaceutical industry has seen significant advancements in the treatment of multiple myeloma, a type of cancer that affects plasma cells in the bone marrow. Among these advancements, Carfilzomib has emerged as a critical player. This proteasome inhibitor, marketed under the brand name Kyprolis, has made substantial impacts in the management of multiple myeloma. In this blog, we will explore the current state of theCarfilzomib market, its growth drivers, opportunities, and future outlook.

Free Sample pdf copy:

What is Carfilzomib?

Carfilzomib is a next-generation proteasome inhibitor used in the treatment of multiple myeloma, especially in patients who have relapsed or are refractory to other therapies. Unlike its predecessor, bortezomib, Carfilzomib is known for its more selective action on the proteasome, potentially leading to fewer side effects and enhanced efficacy. Approved by the FDA in 2012, it has since become an integral part of combination therapies for multiple myeloma.

Carfilzomib Market Landscape

Growth Drivers

Rising Incidence of Multiple Myeloma: The increasing number of multiple myeloma cases globally is a significant driver for the Carfilzomib market. As the global population ages, the prevalence of multiple myeloma is expected to rise, leading to a higher demand for effective treatments.

Advancements in Treatment Protocols: Carfilzomib is often used in combination with other drugs like lenalidomide and dexamethasone, enhancing its effectiveness. This combination therapy approach has shown promising results, making Carfilzomib a preferred choice in advanced treatment regimens.

Increasing Awareness and Diagnosis: Improved diagnostic techniques and greater awareness about multiple myeloma have led to earlier detection and treatment. This trend is likely to boost the demand for Carfilzomib as part of first-line and subsequent lines of treatment.

Ongoing Clinical Trials: Continuous research and clinical trials exploring new indications and combination therapies for Carfilzomib are expanding its potential market. Studies focusing on different stages of multiple myeloma and other cancers could open new avenues for Carfilzomib use.

Carfilzomib Market Challenges

High Cost of Treatment: Carfilzomib is a high-cost drug, and its price can be a barrier to access, particularly in developing countries. The high cost of treatment may limit its market potential and lead to a preference for alternative therapies.

Side Effects and Resistance: Although Carfilzomib is well-tolerated, some patients may experience side effects such as cardiovascular issues or renal complications. Additionally, resistance to the drug can develop, leading to the need for alternative therapies.

Competition from Other Therapies: The multiple myeloma treatment landscape is competitive, with several other proteasome inhibitors and novel therapies in development. This competition can impact Carfilzomib’s market share and pricing strategies.

Market Opportunities

Expanding Indications: Research into expanding the use of Carfilzomib to other types of cancer or earlier stages of multiple myeloma could provide significant market opportunities. Successful clinical trials in these areas could lead to new indications and broaden its market.

Developing Markets: As healthcare infrastructure improves in developing regions, there ispotential for growth in these Carfilzomib Market Strategic partnerships and pricing strategies could enhance Carfilzomib’s reach in these areas.

Combination Therapies: Exploring new combination therapies and optimizing treatment regimens can improve patient outcomes and increase the demand for Carfilzomib. Collaborations with other pharmaceutical companies and research institutions could drive innovation in this space.

Carfilzomib Market Future Outlook

The Carfilzomib market is poised for continued growth driven by advancements in treatment protocols and increasing prevalence of multiple myeloma. However, challenges such as high treatment costs and competition from alternative therapies will require strategic planning and innovation.

The future of Carfilzomib will likely involve ongoing research and development to expand its therapeutic indications and improve patient outcomes. As the market evolves, stakeholders will need to navigate these dynamics to maximize the potential of Carfilzomib in the treatment of multiple myeloma and beyond.

Conclusion

Carfilzomib Market has made asignificant impact in the management of multiple myeloma, and its market prospects remain strong. With ongoing advancements in treatment protocols, increasing awareness, and expanding indications, Carfilzomib is set to continue playing a crucial role in cancer therapy. However, addressing market challenges and seizing emerging opportunities will be essential for stakeholders to fully realize the potential of this innovative drug.

[biotech-news-feed]

Opinion/decision on a Paediatric investigation plan (PIP): Kyprolis, carfilzomib, decision type: PM: decision on the application for modification of an agreed PIP, therapeutic area: Haematology-Hemostaseology;Oncology, PIP number: P/0107/2023 #BioTech #science

[sophiareddy123]

The orphan drugs market is segmented by Drug Type (Biological, Non-biological), Top Selling Drugs (Revlimid, Darzalex, Rituxan, Tafinlar, Ninlaro, Imbruvica, Myozyme, Soliris, Jakafi, Kyprolis, Other Top Selling Drugs), Disease Type (Oncology, Hematology, Neurology, Cardiovascular, Other Disease Types) and Geography (North America, Europe, Asia-Pacific, Middle East and Africa, and South America). 

Download Free Sample Report - orphan drugs market

[newswireml]

Post-Transplant Triplet Bests Lenalidomide Maintenance Alone in Myeloma#PostTransplant #Triplet #Bests #Lenalidomide #Maintenance #Myeloma

Use of a triple-drug maintenance combination appeared to improve progression-free survival (PFS) in patients with newly diagnosed multiple myeloma following induction therapy and autologous stem-cell transplantation, an interim analysis of the phase III ATLAS trial suggested. In an intention-to-treat analysis, the median PFS was 59.1 months for patients treated with carfilzomib (Kyprolis),…

[rogalbert]

The habit of life and a new chemo protocol.

The habit of life and a new chemo protocol.

July 18th, 2022 So, we went to the Hospital this morning to the nuclear imaging department to get a baseline assessment of how well my heart is pumping blood. That’s in preparation for my initiation into a new chemotherapy regime starting tomorrow since the one I was just on including lenalidomide, dexamethasone, and Daratumumab wasn’t working anymore and it was producing some very interesting…

[michaelmyeloma-blog]

Myeloma Therapy: #KRd . 💧#Kyprolis (#carfilzomib) (2nd pic): is an anti-cancer drug that falls under the class of drugs know as PROTEASOME INHIBITORS. Proteasomes are protein complexes that help cells (including cancer cells) dispose of old proteins so they can be replaced by newer, healthier versions. PROTEASOME INHIBITORS are drugs that prevent cancer cells from doing this & as their old proteins pile up & are not replaced, the cancer cells die. I get this drug twice a week (Thursday’s & Friday’s through an IV). . 💊 #Revlimid (#lenolidomide): is a drug that falls into a class of drugs called IMMUNOMODULATORY DRUGS or “IMiDs). These drugs are a mainstay of standard regimes used to treat #MultipleMyeloma. IMiDs work by regulating certain aspects of the immune system. They can activate certain immune cells, prevent certain types of growth signals for cancer cells, & they can also directly kill #myeloma cells 💣! I take this pill once a day. . 💊 #Dexamethasone: this is a powerful steroid that is used in combination with the other two drugs above to kill myeloma cells! Steroids provide a number of benefits to #MyelomaTreatment. In high doses, they can kill multiple myeloma cells; they can decrease inflammation by stopping white blood cells from flowing to the disease-affected areas, helping relieve pain & pressure; & they can also help reduce nausea & vomiting caused by one’s therapy. I take 10 pills once a week! . 💧 Zometa (zoledronic acid) (not pictured): is a bone strengthener used to treat a number of bone diseases, including multiple myeloma. As #myeloma is found in the bone marrow, lesions can be found on the bones & one’s bones have a tendency to weaken and are at risk of breaking. This is given once a week as a transfusion. . 💊 SMZ-TMP: Myeloma already causes one’s immune system to be low, but chemotherapy does as well, so I have to take this anti-bacterial medication preventatively. . 💊 Acyclovir: Similarly to SMZ-TMP, this is taken preventatively to avoid viruses such as shingles. . 💊 Prochlorper: this prevents nauseaea. Luckily, I haven’t had to use it! . 💊 Baby Asprin: Revlimid can cause blood clots. . 💊 Ativan (lorazepam): need to 😴 . #MMSM (at Santa Monica Hematology-Oncology Consultants) https://www.instagram.com/p/Btb2yRZhwnHiDNuoDeA3UjWDS4V4oVyuDro8Xs0/?utm_source=ig_tumblr_share&igshid=111f2d8bpabg0

[medicaltrend]

FDA approved Johnson & Johnson Darzalex Faspro: combined with Kyprolis + dexamethasone for the treatment of multiple myeloma (MM)!

[udaycmi]

Blood Cancer Drugs Market to Generate Exciting Opportunities in the Industry by 2027

The global blood cancer drugs market is anticipated to reach USD 55.6 billion by 2025 according to a new report published by Polaris Market Research. The report ‘Blood Cancer Drugs Market [By Blood Cancer Type (Leukemia (Acute Myeloid Leukemia, Chronic Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Lymphocytic Leukemia), Lymphoma (Hodgkin Lymphoma, Non-Hodgkin Lymphoma (B-Cell Lymphoma, T-Cell Lymphoma)), and Myeloma; By Drugs (Rituaxan/Mabthera (Rituximab), Gleevac/Glivec (Imatinib), Revlimid (Lenalidomide), Velcade (Bortezomib), Tasigna (Nilotinib), Pomalyst (Pomalidomide), Vidaza (Azacitidine), Kyprolis (Carfilzomib), Adcetris (Brentuximab Vedotin), and Others); By Treatment Approaches (Chemotherapeutic, mAbs/Targeted Therapies, and Immunotherapeutic); By Region]: Market Size & Forecast, 2017 – 2025’ provides insights on the current market scenario and the future prospects.

The demand for blood cancer drug is primarily driven by growing death incidences by blood cancer, and continuous innovation for developing novel treatments with the help of several ongoing clinical trials. Moreover, increasing research and development of biological and targeted therapies as treatment will spur the blood cancer drugs market during the upcoming period. However, the high price of drugs and the stringent government policies will limit the growth of blood cancer drugs market during the forecast period.

Get Sample copy of this report: https://www.polarismarketresearch.com/industry-analysis/global-blood-cancer-drugs-market/request-for-sample

Most of the blood cancers start in the bone marrow, where blood is produced. In blood cancer the growth of normal blood cells is dislodged by the uncontrollable growth of abnormal blood cells. These cancerous cells prevent the blood from performing many of its functions. Hence, the existing treatments of blood cancer are being the foundation for developing the new drugs. The steady flow of the blood cancer drugs has created opportunity for research and development in the existing market. For instance, Amgen Inc. received approval for BLINCYTO in July 2017, which is used in treating B-cell precursor Acute Lymphoblastic leukemia. Similarly, European blood cancer drugs market witnessed the approvals of Gazyvaro, by Roche AG that is used in treating advanced follicular lymphoma. Also, novel technologies like CAR-T are likely to be launched this year.

The global blood cancer drugs market is segmented into blood cancer type, drugs and treatment approaches. On the basis of blood cancer type, the global blood cancer drugs market is segmented into leukemia, lymphoma and myeloma. The lymphoma segment is expected to drive the majority market of blood cancer drugs followed by leukemia. The global market of this segment is primarily driven by the increasing prevalence of lymphoma, and presence of effective treatments in the market. On the basis of drugs, the global blood cancer drugs market is further categorized into Rituaxan/Mabthera (Rituximab), Gleevac/Glivec (Imatinib), Revlimid (Lenalidomide), Velcade (Bortezomib), Tasigna (Nilotinib), Pomalyst (Pomalidomide), Vidaza (Azacitidine), Kyprolis (Carfilzomib), Adcetris (Brentuximab Vedotin), and Others. This continuous innovation for treating various sub-types of blood cancers has led to the development of novel types of treatments. For instance, the combination of Revlimid and Velcade has emerged as the preferential drugs in trials for treating multiple myeloma.

The leading companies operating in this industry include Johnson & Johnson Inc., Amgen Inc., Bayer AG., Pfizer, Inc., AbbVie Inc., Roche Holding AG., Celgene Corporation, AstraZeneca, Novartis AG, GlaxoSmithKline PLC, Merck & Co., Inc., and Eli Lily & Co. among others.

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About Polaris Market Research

Polaris Market Research is a global market research and consulting company. The company specializes in providing exceptional market intelligence and in-depth business research services for our clientele spread across different enterprises. We at Polaris are obliged to serve our diverse customer base present across the industries of healthcare, technology, semi-conductors and chemicals among various other industries present around the world

Contact us

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Phone: 1-646-568-9980

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Web: www.polarismarketresearch.com

[marykudro]

Carfilzomib for multiple myeloma is an effective medication and is sold under the brand name kyprolis. Common side effects of carfilzomib are shortness of breath, fever, weakness, low blood potassium, low blood calcium, insomnia, rash and cough. Carfilzomib comes as a powder inside single-dose vials with a strength of 60 mg. The dosage depends upon various factors like weight, medical condition, and response to treatment. It is not advised to pregnant women as it may cause harm to an unborn baby. It is indicated for the patients with relapsed or refractory multiple myeloma.

[indianfitnesscare]

FDA Offers Full Approval for Amgen’s Blood Cancer Drug ‘Krypolis’

FDA Offers Full Approval for Amgen’s Blood Cancer Drug ‘Krypolis’

The US food and Drug Administration has announced that it has approved Amgen’s supplemental new drug application for Kyprolis in combination with dexamethasone and Revlimid (lenalidomide) for the treatment of refractory multiple myeloma. Krypolis can now be used for treating patients with relapse or refractory multiple myeloma who have received one to three treatment before. The drug was…

[deepadelve]

Multiple Myeloma Market

Multiple Myeloma is a cancer that forms in a type of white blood cell called a plasma cell. Healthy plasma cells help you fight infections by making antibodies that recognize and attack germs. In multiple myeloma, cancerous plasma cells accumulate in the bone marrow and crowd out healthy blood cells.

The Multiple Myeloma Market size across the 8MM i.e. the United States, Eu5(the UK, Germany, France, Italy, Spain), China and Japan, was $16.27bn in 2019 and is increasing with a modest CAGR during the study period (2018-2030), according to DelveInsight, a leading company in healthcare analytics and consulting.

Some key highlights from the Multiple Myeloma report:

The total Multiple Myeloma incident cases are expected to reach     91,520 in 2020 in the 8MM

Higher usage of bortezomib based regimen observed across the     US, Japan and EU5; Bortezomib + Lenalidomide + dex regimen is the     preferred treatment choice in the US and Japan in the first-line     compared to Bortezomib + Melphalan ± Prednisone and Bortezomib + dex     regimen in EU5. In the case of China, higher usage of thalidomide based     regimen found in the first-line setting

Key Companies like GlaxoSmithKline, Bristol-Myers Squibb, Merck     Sharp & Dohme Corp., Pfizer, Takeda, AbbVie, Roche, Janssen Research     & Development, Amgen, AstraZeneca, etc. are fuelling the Multiple     Myeloma market size growth.

Patent expiry of multiple blockbuster drugs like Darzalex, Revlimid,     Pomalyst and Kyprolis is on the lines to expire from 2026 onwards, and     this will erode the sales value significantly and the market is expected     to decline from 2028 onwards due to cumulative impacts of patent expiry.

Multiple Myeloma Key Players: Kiadis Pharma, CASI Pharmaceuticals, NOXXON Pharma, MorphoSys), Sana Biotechnology, Ayala Pharmaceuticals, Cellectar Biosciences, Bristol-Myers Squibb, Poseida Therapeutics, AbbVie/Genentech, Janssen Research and Development, Nanjing Legend Biotech, Genenta Science, Biotest AG, Teneobio, iCell Gene Therapeutics, Juno Therapeutics, Arch Oncology, Regeneron Pharmaceuticals, Incyte Corporation, NexImmune Inc., Chongqing Precision Biotech, Novartis, CASI Pharmaceuticals, Ionis Pharmaceuticals, AgenTus Therapeutics, Biohaven Pharmaceuticals, CRISPR Therapeutics, Pfizer, GlaxoSmithKline, Seagen Inc., Heidelberg Pharma, Bluebird Bio, C4 Therapeutics, Inc., Hoffmann-La Roche, Phosplatin Therapeutics, Arcellx, Inc., HitGen Inc., Boehringer Ingelheim, I-Mab Biopharma, Celyad Oncology, Amgen and others

Key Multiple Myeloma Pipeline Therapies: TNB-383B, ONC201, AO-176, JCARH125, REGN5458, INCB001158, TAK-573, NEXI-002 T Cells, PHE885, CID-103, ION251, EMB-06, agenT-797, CTX120, PF-06863135, SEA-BCMA, AEVI-007, HDP-101, bb21217, CFT7455, RO7425781, PT-112, HG146, CYAD-211, AMG 701, Nivolumab, ventoclax, RAPA-201 autologous T cells, K NK004, CID 103, NOX-A12, TJ202, APG-2575, AL 102, CLR 131 and others.

Scope of the Report

Geography Covered: 8MM - The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), Japan, and China.

Study Period: 3-year historical and 11-year forecasted analysis (2017-2030).

Markets Segmentation: By Geographies, By Therapies (Forecasted + Historical).

Companies Covered

Analysis: Comparative and conjoint analysis of emerging therapies, Attribute Analysis

Case Studies

KOL's Views

Analyst's View

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About DelveInsight

DelveInsight is a leading Business Consultant, and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing end to end comprehensive solutions to improve their performance.  Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve.

[newsbulletin]

Blood Cancer Drugs Market Competitive Strategies And Global Review 2017-2025

New York, NY 13 May 2021: The global blood cancer drugs market is anticipated to reach USD 55.6 billion by 2025 according to a new report published by Polaris Market Research. The report ‘Blood Cancer Drugs Market [By Blood Cancer Type (Leukemia (Acute Myeloid Leukemia, Chronic Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Lymphocytic Leukemia), Lymphoma (Hodgkin Lymphoma, Non-Hodgkin Lymphoma (B-Cell Lymphoma, T-Cell Lymphoma)), and Myeloma; By Drugs (Rituaxan/Mabthera (Rituximab), Gleevac/Glivec (Imatinib), Revlimid (Lenalidomide), Velcade (Bortezomib), Tasigna (Nilotinib), Pomalyst (Pomalidomide), Vidaza (Azacitidine), Kyprolis (Carfilzomib), Adcetris (Brentuximab Vedotin), and Others); By Treatment Approaches (Chemotherapeutic, mAbs/Targeted Therapies, and Immunotherapeutic); By Region]: Market Size & Forecast, 2017 – 2025’ provides insights on the current market scenario and the future prospects.

The demand for blood cancer drug is primarily driven by growing death incidences by blood cancer, and continuous innovation for developing novel treatments with the help of several ongoing clinical trials. Moreover, increasing research and development of biological and targeted therapies as treatment will spur the blood cancer drugs market during the upcoming period. However, the high price of drugs and the stringent government policies will limit the growth of blood cancer drugs market during the forecast period.

Most of the blood cancers start in the bone marrow, where blood is produced. In blood cancer the growth of normal blood cells is dislodged by the uncontrollable growth of abnormal blood cells. These cancerous cells prevent the blood from performing many of its functions. Hence, the existing treatments of blood cancer are being the foundation for developing the new drugs. The steady flow of the blood cancer drugs has created opportunity for research and development in the existing market. For instance, Amgen Inc. received approval for BLINCYTO in July 2017, which is used in treating B-cell precursor Acute Lymphoblastic leukemia. Similarly, European blood cancer drugs market witnessed the approvals of Gazyvaro, by Roche AG that is used in treating advanced follicular lymphoma. Also, novel technologies like CAR-T are likely to be launched this year.

Request For Sample Copy @ https://www.polarismarketresearch.com/industry-analysis/global-blood-cancer-drugs-market/request-for-sample

The global blood cancer drugs market is segmented into blood cancer type, drugs and treatment approaches. On the basis of blood cancer type, the global blood cancer drugs market is segmented into leukemia, lymphoma and myeloma. The lymphoma segment is expected to drive the majority market of blood cancer drugs followed by leukemia. The global market of this segment is primarily driven by the increasing prevalence of lymphoma, and presence of effective treatments in the market. On the basis of drugs, the global blood cancer drugs market is further categorized into Rituaxan/Mabthera (Rituximab), Gleevac/Glivec (Imatinib), Revlimid (Lenalidomide), Velcade (Bortezomib), Tasigna (Nilotinib), Pomalyst (Pomalidomide), Vidaza (Azacitidine), Kyprolis (Carfilzomib), Adcetris (Brentuximab Vedotin), and Others. This continuous innovation for treating various sub-types of blood cancers has led to the development of novel types of treatments. For instance, the combination of Revlimid and Velcade has emerged as the preferential drugs in trials for treating multiple myeloma.

On the basis of treatment approaches the global blood cancer drugs market is further segmented into Chemotherapeutic, mAbs/Targeted Therapies, and Immunotherapeutic. Due to availability of variety of chemotherapeutic agent in the market chemotherapeutic drugs are expected to hold the higher share in blood cancer drugs market. Moreover, their effectiveness for the treatment of blood cancer and increasing number of cancer patients globally has garnered more demand for chemotherapeutic drugs throughout the world.

Geographically, the global blood cancer drugs market is segmented into North America, Europe, Asia Pacific, and the rest of the world. North America dominates the blood cancer drugs market which is followed by Europe and Asia Pacific. Favorable reimbursement policies, surge in R&D investments of various companies, as well as the increase in the number of blood cancer treatments are some of the major factors responsible for the growth of North America’s blood cancer drugs market. Moreover, Asia-Pacific region has been identified as the lucrative market for the for blood cancer drugs due to increasing awareness of the use of these drugs, increased healthcare expenditure, and rising per capita disposable income. These are some of the major factors which are influencing the growth of the blood cancer drugs in Asia-pacific region.

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The leading companies operating in this industry include Johnson & Johnson Inc., Amgen Inc., Bayer AG., Pfizer, Inc., AbbVie Inc., Roche Holding AG., Celgene Corporation, AstraZeneca, Novartis AG, GlaxoSmithKline PLC, Merck & Co., Inc., and Eli Lily & Co. among others.

Key Findings from the study suggest blood cancer drugs in the market are much innovative and manufacturers are progressively concentrating on innovation of combination drugs. Companies are in a stage of development of new drugs in order to provide novel treatments for blood cancer. The immunotherapy segment is anticipated to grow at a high growth rate over the forecast period. The growth of this segment is primarily driven by increased awareness for its use as an alternative and effective treatment for blood cancer. North America is presumed to dominate the global blood cancer drugs market over the forecast period. Asia Pacific region which shows signs of high growth potential owing to the booming economies of India, and China.

Polaris Market Research has segmented the global blood cancer drugs market on the basis of type, drugs, treatment approaches and region:

Blood cancer drugs market Size and Forecast, 2017-2025 by Blood Cancer Type

Lymphoma

Leukemia

Myeloma

Hodgkin Lymphoma

Non-Hodgkin Lymphoma

B-cell Lymphoma

T-cell Lymphoma

Diffuse Large B-Cell Lymphoma

Mantle Cell Lymphoma

Burkitt Lymphoma

Central Nervous System Lymphoma

Precursor T-Lymphoblastic Lymphoma

Peripheral T-Lymphoma

Acute Myeloid Leukemia

Chronic Myeloid Leukemia

Acute Lymphoblastic Leukemia

Chronic Lymphocytic Leukemia

Multiple Myeloma

Blood cancer drugs market Size and Forecast, 2017-2025 by Drugs

Rituaxan/Mabthera (Rituximab)

Gleevac/Glivec (Imatinib)

Revlimid (Lenalidomide)

Velcade (Bortezomib)

Tasigna (Nilotinib)

Pomalyst (Pomalidomide)

Vidaza (Azacitidine)

Kyprolis (Carfilzomib)

Adcetris (Brentuximab Vedotin)

Others

Blood cancer drugs market Size and Forecast, 2017-2025 by Treatment Approaches

Chemotherapeutic

mAbs/Targeted Therapies

Immunotherapeutic

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About Polaris Market Research

Polaris Market Research is a global market research and consulting company. The company specializes in providing exceptional market intelligence and in-depth business research services for our clientele spread across different enterprises.

Contact Us:

Polaris Market Research

Phone: 1–646–568–9980

Email: sales@polarismarketresearch.com

Web: http://www.polarismarketresearch.com

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Best multiple myeloma treatment in India

Multiple myeloma is cancer of the plasma cells (a type of white blood cells) of the bone marrow. Plasma cells are protein-making cells that generally produce the different kinds of antibodies for our immune system. In multiple myeloma, the plasma cells become malicious and cancerous. These myeloma cells stop making different forms of protein in response to the immune system's needs and instead start to produce a single abnormal type of protein sometimes termed a monoclonal or M protein. Multiple myeloma plasma cell populations accumulate in the bone marrow, and these collections of cells called plasmacytomas can erode the hard outer shell or cortex of the bone that normally surrounds the marrow. These weakened bones show thinning of the bone, as seen in nonmalignant osteoporosis or what appear to be punched out or lytic bone lesions. People often refer to multiple myeloma simply as myeloma (also termed Kahler's disease after the physician who first described this cancer). The disease usually occurs in people past middle age.

In India, there are large number of options available for Best multiple myeloma treatment in India.

However, rarely it can occur in a child. One type of myeloma-related plasma cell neoplasm is called a monoclonal gammopathy of undetermined significance (MGUS). In MGUS, medical professionals only find low levels of M protein and people have no symptoms; MGUS infrequently develops into multiple myeloma.

Plasma cell neoplasm is another name for multiple myeloma. Causes of multiple myeloma What triggers plasma cells into malicious multiple myeloma is unknown. The cancerous myeloma plasma cells proliferate and crowd out normal plasma cells and can corrode areas of bones. The proteins produced in large amounts can cause many of the symptoms of the disease by making the blood more viscous and depositing the proteins in organs that can interfere with the functions of the kidneys, nerves, and immune system.

Causes of multiple myeloma are not known exactly. But patients more likely to get affected • older than 65 years • people of African-American origin • overweight or obese people • family member with it

Stages of multiple myeloma

There are four stages of multiple myeloma. While many health care professionals use different staging, these are various stages cited by many clinicians:

• Smoldering: multiple myeloma with no symptoms • Stage I: early disease with little anemia, relatively small amount of M protein and no • bone damage • Stage II: more anemia and M protein as well as bone damage • Stage III: still more M protein, anemia, as well as signs of kidney damage Because staging criteria differ according to different groups, some clinicians simply define the individual's multiple myeloma without assigning a stage and simply estimate a prognosis for their patient.

Symptoms of multiple myeloma

Patients with myeloma may be asymptomatic with an unexplained increase in protein in the blood. With more advanced disease, some myeloma patients may have weakness due to anemia caused by inadequate production of red blood cells, with bone pain due to the bone damage, and as the abnormal M protein can accumulate and damage the kidneys resulting in patient’s unexplained kidney damage and decreased kidney function. Multiple myeloma cancer cells may be in or outside the bone marrow.

The following symptoms and signs of multiple myeloma -

• Anemia • Bleeding • Nerve damage • Bone tenderness or pain, including back pain • Enlarged tongue • Skin lesions (rash) • Infections Weakness, fatigue or tiredness • Kidney failure and/or other end-organ damage• Spinal cord compression • • Loss of appetite and weight loss • Leg swelling • Hypocalcaemia • Diagnosis of multiple myeloma • First sign of multiple myeloma is found when a routine blood test shows an abnormal amount of protein in the bloodstream or an unusual stickiness of red blood cells causing them to stack up almost like coins, an unusual formation for red blood cells. The health care professional will do a history and physical exam, looking for signs and symptoms of multiple myeloma. If multiple myeloma is suspected, several studies help confirm the diagnosis.

They include a bone marrow aspiration and biopsy most commonly from the large bones of the pelvis. Cells obtained from the marrow are studied by a pathologist to determine if there is one (plasmacytoma) or more (multiple myeloma) abnormal types or numbers of cells • Medical professionals also study a sample of the bone marrow aspirate for more detailed • Characteristics such as the presence or absence of abnormal numbers or types of chromosomes (DNA) by what is called cytogenetic testing.

Bone marrow biopsy can assess the concentrations of cells in the marrow and the presence of abnormal invasive growth of cellular elements. • Blood testing and urine testing by several methods can determine levels and types of National Comprehensive Cancer Network (NCCN) recommended that health care professionals use a serum free light chain assay and fluorescence in situ hybridization (FISH) test to further • Monoclonal protein produced and if there is kidney damage.

Identify multiple myeloma in patients

X-ray studies to identify skeletal lesions and MRI for spinal cord lesions in multiple myeloma.

Medical treatment for multiple myeloma

The therapy is decided based upon the patient's condition and the cancer management team, made with the patient's input. The choices for treatment(s) often include combinations of drugs, some of which medical professionals give as pills and others by intravenous injection.

These include drugs that affect or modulate the immune system, steroids, and some oral or injectable chemotherapy drugs. These are usually used in combinations. There may be a role for high-dose chemotherapy followed by the administration of bone marrow called a stem cell transplant. Numerous factors come into play in determining whether to do such a transplant. Other medical treatments may include steroids, bisphosphonate therapy, blood or platelet transfusions, plasmapheresis, and other combination therapy depending on the individual patient's disease stage.

Radiation therapy may treat painful areas of bone damage. Surgeons can surgically repair broken bones in many cases.

There are many drugs used to treat multiple myeloma. Medical professionals often use the following drugs in combination with dexamethasone,

• Bortezomib Velcade -- protease inhibitor • Lenalidomide (Revlimid) -- immune cell modulation • Melphalan (Alkeran) -- alkylating agent that is toxic to myeloma cells • Carfilzomib (Kyprolis) -- protease inhibitor that is FDA approved usually for patients • who have failed a previous treatment • Daratumumab (Darzalex) -- monoclonal antibody that may damage or kill multiple • Myeloma cells (and others) that have CD38 protein on their surface • Elotuzumab (Empliciti) -- a compound that activates the body's natural killer cells to • Destroy multiple myeloma cells, usually in combination with Revlimid and Decadron • Ninlaro (Ixazomib) -- This proteasome inhibitor, in combination with Revlimid and • Dexamethasone, improves the survival rates of some patients with multiple myeloma.

Hospitals offer best multiple myeloma treatment in India, the charges for autologous stem cell transplant ranges between USD 15000 to USD 21000 depending on the status of the disease and individual's response to the treatment provided at the hospitals.

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