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#Adenovirus Vector Vaccine Market Analysis
lalsingh228-blog · 9 months
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Adenovirus Vector Vaccine Market Projected to Show Strong Growth
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The Latest research coverage on Adenovirus Vector Vaccine Market provides a detailed overview and accurate market size. The study is designed considering current and historical trends, market development and business strategies taken up by leaders and new industry players entering the market. Furthermore, study includes an in-depth analysis of global and regional markets along with country level market size breakdown to identify potential gaps and opportunities to better investigate market status, development activity, value and growth patterns. Access Sample Report + All Related Graphs & Charts @: https://www.advancemarketanalytics.com/sample-report/165891-global-adenovirus-vector-vaccine-market
Major & Emerging Players in Adenovirus Vector Vaccine Market:- Creative Biolabs (United States), Sartorius AG (Germany), Lonza (Switzerland), Merck KGaA (Germany), Cobra Biologics (United States), Thermo Fisher Scientific (United States), Boehringer Ingelheim (Germany), Oxford Biomedica (United Kingdom), Advanced Bioscience Laboratories (United States). The Adenovirus Vector Vaccine Market Study by AMA Research gives an essential tool and source to Industry stakeholders to figure out the market and other fundamental technicalities, covering growth, opportunities, competitive scenarios, and key trends in the Adenovirus Vector Vaccine market. Adenovirus represents the class of the genetically diverse DNA viruses that can cause non-life-threatening infections related to eyes, respiratory system, gastrointestinal lining and other parts. These viruses represent promising results as a vector for delivering target antigens to various hosts due to excellent ability induce immune response. Due to these property, the new studies concluded positive results for use of adenovirus for both gene therapy and vaccine production. Adenovirus-based vectors shows various benefits when compared to other viral vectors such as wide range of tissue tropism, ease of genetic manipulation especially for large transgene DNA insertions, superior ability to induce robust transgene-specific T cell and antibody responses, easy production of the adenovirus based vaccines at large scale. Due to this, it has emerged as a preferred choice for delivering vaccine for both humans as well as animals.
In February 2021, the Janssen Biotech, a part of Johnson and Johnson submitted Emergency Use Authorization (EUA) to the US Food and Drug Administration (FDA), for its investigational single-dose coronavirus 2019 (COVID-19) vaccine candidate. The vaccine Ad26.COV2.S, is a recombinant, replication-incompetent adenovirus serotype 26 (Ad26) vector encoding a full-length and stabilized SARS-CoV-2 spike (S) protein
In January 2021, Thermo Fisher Scientific, a company offering range of instrumentation, reagents and consumables, and software and services acquired the viral-vector manufacturing business of the Novasep, a pharmaceutical company for approximately USD 875 million in cash. This acquisition is a step towards expanding Thermo Fisher capabilities in the cell and gene vaccines and therapies worldwide. The titled segments and sub-section of the market are illuminated below: by Type (Adenovirus-based tuberculosis vaccine, Adenovirus-based HIV vaccine, Adenovirus-based influenza vaccine, Others), Application (Human, Animals), End-user (Hospitals, Ambulatory Surgical Center, Research Institutes, Others) Market Trends: Increasing investment in vaccine and drug development
Rising collaboration between the pharmaceutical companies and CROs for development of adenovirus vector vaccine
Opportunities: Emergence of adenovirus vectored vaccines for COVID-19      
Production of low cost adenovirus vaccines
Market Drivers: Growing prevalence of chronic medical conditions
Rise in demand for efficient vaccines to treat infectious diseases Enquire for customization in Report @: https://www.advancemarketanalytics.com/enquiry-before-buy/165891-global-adenovirus-vector-vaccine-market Some Point of Table of Content: Chapter One: Report Overview Chapter Two: Global Market Growth Trends Chapter Three: Value Chain of Adenovirus Vector Vaccine Market Chapter Four: Players Profiles Chapter Five: Global Adenovirus Vector Vaccine Market Analysis by Regions Chapter Six: North America Adenovirus Vector Vaccine Market Analysis by Countries Chapter Seven: Europe Adenovirus Vector Vaccine Market Analysis by Countries Chapter Eight: Asia-Pacific Adenovirus Vector Vaccine Market Analysis by Countries Chapter Nine: Middle East and Africa Adenovirus Vector Vaccine Market Analysis by Countries Chapter Ten: South America Adenovirus Vector Vaccine Market Analysis by Countries Chapter Eleven: Global Adenovirus Vector Vaccine Market Segment by Types Chapter Twelve: Global Adenovirus Vector Vaccine Market Segment by Applications What are the market factors that are explained in the Adenovirus Vector Vaccine Market report?
– Key Strategic Developments: Strategic developments of the market, comprising R&D, new product launch, M&A, agreements, collaborations, partnerships, joint ventures, and regional growth of the leading competitors.
– Key Market Features: Including revenue, price, capacity, capacity utilization rate, gross, production, production rate, consumption, import/export, supply/demand, cost, market share, CAGR, and gross margin.– Analytical Tools: The analytical tools such as Porter’s five forces analysis, SWOT analysis, feasibility study, and investment return analysis have been used to analyze the growth of the key players operating in the market. Buy This Exclusive Research Here: https://www.advancemarketanalytics.com/buy-now?format=1&report=165891 Definitively, this report will give you an unmistakable perspective on every single reality of the market without a need to allude to some other research report or an information source. Our report will give all of you the realities about the past, present, and eventual fate of the concerned Market. Thanks for reading this article; you can also get individual chapter wise section or region wise report version like North America, Europe or Asia. Contact US : Craig Francis (PR & Marketing Manager) AMA Research & Media LLP Unit No. 429, Parsonage Road Edison, NJ New Jersey USA – 08837 Phone: +1 201 565 3262, +44 161 818 8166 [email protected]
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123567-9qaaq9 · 4 months
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Detailed Report on Upstream Bioprocessing Market  | BIS Research 
Upstream Bioprocessing refers to the initial phase of Biopharmaceutical production that involves the preparation and growth of cells or microorganisms to produce the desired biological product. 
The Global Upstream Bioprocessing Market was valued at $250.1 million in 2023 and is expected to reach $1,639.1 million by 2033, growing at a CAGR of 20.68% between 2023 and 2033.
Upstream Bioprocessing Overview 
Upstream Bioprocessing is an advanced manufacturing approach used in the production of biological products, including pharmaceuticals, biopharmaceuticals, and industrial enzymes. This method is characterized by the uninterrupted flow of materials through the production process, from the initial cultivation of cells or microorganisms to the final product purification.
Grab the free sample page click here 
Key Stages involved in Upstream Bioprocessing 
Cell Line Development 
Media Preparation 
Bioreactor Cultivator 
Monitoring and Control
Key Applications for Upstream Bioprocessing 
Biopharmaceutical Production 
Monoclonal Antibodies 
Recombinant Proteins 
Vaccines 
Gene Therapy- Production of viral vectors (such as lentivirus and adenovirus) for delivering genetic material in gene therapy applications.
Cell Therapy - Cultivation of stem cells and other cell types used in regenerative medicine to repair or replace damaged tissues and organs.
Agricultural Biotechnology - Development of genetically modified organisms (GMOs) and biofertilizers to enhance crop yield, pest resistance, and nutrient utilization.
Market Drivers for Upstream Bioprocessing Market  
Growing demand for Biopharmaceuticals 
Advancements in Biotechnology 
Expansion of Personalized Medicines 
Technological Innovations 
Environmental Sustainability 
These market drivers collectively contribute to the growing adoption and expansion of the Upstream Bioprocessing Market
Recent Developments in the Upstream Bioprocessing Market
• Waters and Sartorius expanded their partnership to develop integrated analytical tools for downstream biomanufacturing following their successful collaboration in upstream processes. •  Sartorius and Repligen Corporation launched an integrated system with Biostat STR and XCell ATF for upstream process intensification.
Visit our Life Sciences and Biopharma Vertical page for better understanding 
Key Players in the market 
•   3M •   Bio-Rad Laboratories, Inc. •   Thermo Fisher Scientific, Inc. •   Merck KGaA •   Sartorius AG •   Danaher Corporation
Key Questions Answered
Q What is the estimated global market size for the Upstream Bioprocessing Market ?
Q What future trends are expected in the Upstream Bioprocessing Market ?
Q  What does the supply chain of the Upstream Bioprocessing Market  look like?
QWhat does the value chain of the Upstream Bioprocessing Market  look like?
Q  What is the regulatory framework within the Upstream Bioprocessing Market ?
Q  What is the patent analysis trend based on country and year in the Upstream Bioprocessing Market ?
Q  How has the COVID-19 outbreak affected the future trajectory of the Upstream Bioprocessing Market ?
Q What are the next frontiers in the Upstream Bioprocessing Market ?
Conclusion
Upstream bioprocessing is a critical and foundational phase in the production of biopharmaceuticals, playing a vital role in the cultivation and optimization of cells or microorganisms to produce high-quality biological products.
As the biopharmaceutical industry continues to evolve, upstream bioprocessing will remain a cornerstone, driving the development of new and innovative therapies that improve patient outcomes and address unmet medical needs.
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Viral Vector—Perusal on Adeno-associated Viruses (AAVs) in Gene Therapy Development
The medical industry expects viral vectors to grow in prominence in transferring genetic material into the genetic composition of cells. Adeno-associated Viruses (AAVs) have become sought-after in gene therapy as they can deliver genetic material to cells and do not cause disease. Predominantly, adenovirus, retrovirus, herpes simplex virus and lentivirus, among others, are used to transfer genetic material into cells’ genetic composition. Technological advancements in manufacturing AAV vectors have encouraged stakeholders to boost their portfolios. An uptick in research activities in viral vector-based cell and gene therapies has redefined the global landscape. For instance, in 2020, over 100 gene-therapy products were observed in clinical trials.
Pharma companies, investors, venture capitalists and other stakeholders will possibly explore the growth potential in viral vectors. The final report, along with the database, will deep-dive into the following industry dynamics:
• AAV vectors approved by governing bodies, including FDA and the European Medicines Agency. Zolgensma was approved by EMA and FDA in 2020 and 2019, respectively, while Luxturna received the green signal from FDA in 2017 and EMA in 2018. 
• Insights on potential challenges for AAV manufacturers, such as cost, degradation during supply chain and preparation of stable viral vectors.
• Influence of the COVID-19 pandemic on vaccine development.
• Acquisitions of biotech startups
Get your copy or request a free sample of the report “Viral Vector Development - Focus on Adeno-associated Virus, 2018 – 2021,” compiled and published by Grand View Research.
Viral Vector Report Scope
Attribute
Details
Market Lineage
% Captured by AAV within Viral Vectors
Understanding of the parent market and ancillary industries
Plasmid DNA Contract Manufacturing
Cell & Gene Therapy Clinical Trials Market
Industry Dynamics
Viral Vector based gene therapy development
AAV Development workflow
Pipeline for AAV
Capitalist funding in the industry
Development Process
Deep dive Analysis
Understanding of AAV v/s Lentiviral v/s other viral vectors
Cost of manufacturing (based on batch size) - a case study
Case study on setting up a development plant
Competition Analysis in CDMOs
Companies with products in clinical trials
Various bioreactors used for development
Strategic initiatives undertaken in the last 5 years
Observation and Recommendations
This section will summarize the entire study and provide analyst insights with regards to key methods of development, technological advancements, and competitive profiling
Get more insights from our in-depth market intelligence report “Viral Vector Market Size, Share & Trends Analysis Report By Vector Type (Adeno-associated Virus (AAV), Adenovirus, Lentivirus, Retrovirus, Others), By Application, By End-user, By Region, And Segment Forecasts, 2023 – 2030”
About Us
Grand View Research, Inc. is a market research and consulting company that provides off-the-shelf, customized research reports and consulting services. To help clients make informed business decisions, we offer market intelligence studies ensuring relevant and fact-based research across a range of industries, from technology to chemicals, materials and energy. With a deep-seated understanding of varied business environments, Grand View Research provides strategic objective insights.
Find More information @ https://www.grandviewresearch.com/info/trend-reports
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balrajgis · 2 years
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Viral Vectors And Plasmid DNA Manufacturing Market overview by recent opportunities, growth size, regional analysis and forecasts to 2031 | Genelux Corporation, Kaneka Eurogentec S.A., Lonza Group AG
Global Viral Vectors And Plasmid DNA Manufacturing Market report from Global Insight Services is the single authoritative source of intelligence on Viral Vectors And Plasmid DNA Manufacturing Market. The report will provide you with analysis of impact of latest market disruptions such as Russia-Ukraine war and Covid-19 on the market. Report provides qualitative analysis of the market using various frameworks such as Porters’ and PESTLE analysis. Report includes in-depth segmentation and market size data by categories, product types, applications, and geographies. Report also includes comprehensive analysis of key issues, trends and drivers, restraints and challenges, competitive landscape, as well as recent events such as M&A activities in the market.
A viral vector is a virus that has been genetically modified to carry a foreign gene into a cell. The foreign gene may encode a protein that confers a new property to the cell, such as resistance to a particular drug. Alternatively, the foreign gene may be a piece of DNA that the researcher wishes to insert into the cell’s genome.
Get Free Sample Copy of This Report – https://www.globalinsightservices.com/request-sample/GIS21443/
Key Trends
The key trends in viral vectors and plasmid DNA manufacturing technology are:
1. Increasing use of viral vectors and plasmid DNA for gene therapy and vaccine development
2. Improvements in vector design and manufacturing processes
4. Decreasing costs of viral vectors and plasmid DNA
Key Drivers
There are several key drivers of the Viral Vectors and Plasmid DNA Manufacturing market. One of the most important drivers is the increasing demand for gene and cell therapies. Gene therapies are becoming more prevalent as treatments for a variety of conditions, including cancer, genetic disorders, and infectious diseases. In addition, cell therapies are being developed for a variety of applications, including regenerative medicine and immunotherapy.
Key Segments
By Vector Type
Adenovirus
Retrovirus
By Workflow
Upstream Manufacturing
Downstream Manufacturing
By Application
Gene Therapy
Cell Therapy
By End-Use
Pharmaceutical & Biopharmaceutical Companies
Research Institutes
By Region
North AmericaThe U.S.
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Key Players
Genelux Corporation
Kaneka Eurogentec S.A.
Lonza Group AG
MaxCyte, Inc.
Merck KGaA
Novasep Inc.
Vector Biolabs
Vigene Biosciences, Inc.
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10-year forecast to help you make strategic decisions
In-depth segmentation which can be customized as per your requirements
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Excel data pack included with all report purchases
Robust and transparent research methodology
Ground breaking research and market player-centric solutions for the upcoming decade according to the present market scenario
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vicky8588 · 3 years
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Viral Vector and Plasmid DNA Manufacturing Market
Market Overview
The Global "Viral Vector and Plasmid DNA Manufacturing Market" are expected to grow at a high CAGR of 18.8% during the forecasting period (2021-2028).
 The viral vector is referred to as the tool for delivering genetic material into cells. The modified viral vector is used as viral vectors in gene therapy. Plasmid DNA is a bacterial smaller, circular, and extrachromosomal DNA used in different molecular genetic research such as gene therapy, gene transfer, and recombinant DNA technology due to its self-replication property. A gene of interest is transferred into the target cell for studying the function or expression of a gene.
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Market Dynamics:
The market is driven by the increasing demand for viral vectors and plasmid DNA manufacturing for developing DNA vaccines, gene therapy, immunotherapy, and others. There are growing viral vectors & plasmid DNA due to their advantages such as high transfection efficiency, effective gene delivery, and stable gene expression. There is an increase in the number of clinical studies examining the viral vectors' efficacy and safety and plasmid DNA.
 There is an increase in the contract manufacturing business launch for viral vectors and plasmid DNA manufacturing. For instance, in December 2019, Helixmith Co., Ltd. and Genopis had launched the contract manufacturing business for plasmid DNA production. The company would establish additional smaller-scale reactors (60-300 L, 6-30 L) with feasibility runs and start a small-volume production service. Genopis is equipped with the right technologies and quality systems.
 Several companies are entering into a collaboration with several organizations to manufacture viral vectors and plasmid DNA. For instance, in June 2020, Oxford Biomedica plc had entered into a collaboration agreement with the Vaccines Manufacturing and Innovation Centre (VMIC), a not-for-profit organization established to provide the UK’s first strategic vaccine development and advanced manufacturing capability. This five-year agreement would involve the organizations working collaboratively to enable the manufacture of viral vector-based vaccines, contributing to a rapid increase in the United Kingdom domestic capacity for this specialized vaccine manufacturing field. Under the terms of the agreement, VMIC would provide manufacturing equipment for Oxford Biomedica to equip two new GMP manufacturing suites within Oxford Biomedica’s new 7,800 m2 commercial manufacturing center, Oxbox, located in Oxford, United Kingdom.
  Segment Analysis
The global viral vector and plasmid DNA manufacturing market is segmented on the product type as the plasmid DNA, viral vector, and non-viral vector. The viral vector segment accounts for the highest market growth due to the increasing penetration of the viral vectors for targeted delivery, efficient transduction, and controlled gene expression. There is an increase in the viral vectors' usage due to their efficiency in delivering genes into the target cells and protecting the new genes from degradation. Different types of viral vectors such as retrovirus, lentivirus, adenovirus, adeno-associated virus, and herpes simplex virus are used for transferring the nucleic acids into the genetic makeup of cells. Out of these viral vectors, adenovirus and retrovirus are widely used worldwide as these viral vectors have the integration ability with large transgenes and easy production at high titers.
 Several companies are focusing on expanding the manufacturing facilities for the viral vectors to meet the increasing demand. For instance, in May 2019, Thermo Fisher Scientific Inc. had opened its new $90 million viral vector contract development and manufacturing organization (CDMO) site in Lexington, MA. The 50,000-square-foot facility would support the development, testing, and manufacture of viral vectors essential for advancing gene and cell therapies globally.
   Further, the market is also classified based on cancer, genetic disorder, infectious disease, and other diseases. The cancer segment accounts for the highest market share of XX% in 2019 due to the higher usage of the viral vector and plasmid DNA for delivering the anti-cancer genes. Several biotechnology and pharmaceutical companies are examining the viral vectors or plasmid DNA encoding a therapeutic gene, often an immunomodulatory or suicide gene, in the various cancer gene therapy trials. Clinical studies have demonstrated that the injection of a plasmid DNA encoding a cytokine gene has a significant antitumor effect. There is increasing research and development activities for gene therapies and other advanced cell therapies to treat various cancers. The increase in the approval of the viral vector and plasmid DNA-based therapies shall stimulate market growth. For instance, the lentiviral vector-based CAR-T cell therapies' approval for treating Acute Lymphoblastic Leukemia (ALL) and large B cell lymphoma.
 Geographical Presentation
By region, the global viral vector and plasmid DNA manufacturing market is segmented into North America, South America, Europe, Asia-Pacific, Middle-East, and Africa. Among all of the regions, North America dominated the global viral vector and plasmid DNA manufacturing market and is expected to grow at the highest CAGR during the forecasted period due to the increasing number of clinical studies for evaluating the use of the viral vector and plasmid DNA for the treatment of the genetic disorders, cancer, and infectious diseases. The increase in the approval of advanced cell therapies shall stimulate market growth. There is growing research and development activities of gene therapies. Several companies, institutes, associations, and foundations raise the investment and funding to develop gene therapies. The growing initiatives by the Food and Drug Administration (FDA) for improving the regulatory support for cell and gene therapy shall boost the demand for viral vector and plasmid DNA manufacturing.
 The Asia Pacific is expected to witness positive market growth due to the growing clinical transformation and industrialization of advanced therapies medicinal products, including gene therapy manufacturing. There is a presence of several companies manufacturing the viral vector and plasmid DNA. Contract manufacturers are providing several services for viral vector and plasmid DNA manufacturing. There is growing adoption of advanced technologies for manufacturing viral vectors and plasmid DNA.
 View Full Report : https://www.datamintelligence.com/research-report/viral-vector-and-plasmid-dna-manufacturing-market#
 Competitive Analysis
The global viral vector and plasmid DNA manufacturing market are highly competitive with several international and local markets. Product diversification, revenue generation, and opportunities intensify the market competition. Brammer Bio, Cobra Biologics, Cell and Gene Therapy Catapult, FinVector Vision Therapies, Fujifilm Diosynth Biotechnologies, SIRION Biotech, Merck KGaA Inc., Thermo Fisher Scientific, and Uniqure NV are the leading market players with significant market share.
 The major players enter into collaborations, acquisitions, mergers, and licensing activities to increase their market presence. For instance, in August 2019, FUJIFILM Corporation had acquired the Biogen (Denmark) Manufacturing ApS, a large-scale biologics manufacturing site located in Hillerød near Copenhagen, Denmark, from Biogen. The Hillerød Manufacturing site would be the fourth biopharmaceutical manufacturing site of FUJIFILM Diosynth Biotechnologies, a Fujifilm subsidiary, and a leading Contract Development and Manufacturing Organization (CDMO) with expertise in the development and manufacture of biologics and advanced therapies.
 In March 2019, Merck had entered into the non-binding Memorandum of Understanding with Chinese biotech company GenScript for a strategic alliance focusing on a plasmid and viral vector manufacturing. The manufacturing of high-quality plasmids and viral vectors would help in the commercialization of cell and gene therapy. This collaboration would help the company accelerate the industrialization and commercialization of cell and gene therapy in China. Merck would provide GenScript with comprehensive products, training, consulting services covering process design, facility concept design, and quality management system set-up from lab development to large-scale GMP manufacturing.
 In December 2017, MilliporeSigma had entered into the commercial supply agreement to manufacture viral vectors for bluebird bio, Inc., of Cambridge, Massachusetts, for its use in potentially transformative gene therapies. MilliporeSigma would manufacture lentiviral vectors for bluebird bio's drug products developed to treat various rare genetic diseases under the agreement's terms. This contract builds upon MilliporeSigma's deep experience producing viral vectors for gene therapy from clinical to commercial scale.
 In June 2014, Applied Genetic Technologies Corporation had entered into the collaboration with the Sigma-Aldrich Corporation to provide gene therapy manufacturing services to companies developing gene-based therapies. Under the terms of the agreement, the two companies will co-market AGTC's proprietary HAVE manufacturing method with SAFC's cGMP manufacturing capabilities. AGTC will assist clients in engineering AAV-based vectors and the associated helper viruses for HAVE-based manufacturing activities. SAFC will manufacture AAV vectors with the HAVE system to either support initial research or by cGMP requirements to support clinical trial development and eventual commercial production.
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Global Viral Vector Vaccines Market Size, Share, Trends, Growth, Demand and Estimates to 2027
The recently Published Report titled Global Viral Vector Vaccines Market Size, Share, Trends, Growth, Demand and Estimates to 2027 by Axel Reports offers a comprehensive picture of the market from the global view point as well as a descriptive analysis with detailed segmentation, complete research and development history, latest news, offering a forecast and statistic in terms of revenue during the forecast period from 2021-2027. The report covers a comprehensive analysis of key segments, recent trends, competitive landscape, and key factors playing a substantial role in the market are detailed in the report. The report helps vendors and manufacturers to understand the change in the market dynamics over the years.
Get Sample Copy of this Report with the Latest Market Trend and COVID-19 Impact: https://axelreports.com/request-sample/55827
Global Market Segmentation by Top Key-Players: Advanced Bioscience Laboratories Creative Biogene Boehringer Ingelheim Sanofi Brammer Bio Pfizer GE Healthcare
NOTE: Consumer behaviour has changed within all sectors of the society amid the COVID-19 pandemic. Industries on the other hand will have to restructure their strategies in order to adjust with the changing market requirements. This report offers you an analysis of the COVID-19 impact on the Viral Vector Vaccines market and will help you in strategising your business as per the new industry norms.
Report offers: 1. Insights into the intact market structure, scope, profitability, and potential. 2. Precise assessment of market size, share, demand, and sales volume. 3. Authentic estimations for revenue generation and Viral Vector Vaccines Market development. 4. Thorough study of Viral Vector Vaccines Market companies including organizational and financial status. 5. Perception of crucial market segments including, forecast study. 6. Acumen of upcoming opportunities and potential threats and risks in the market.
Market segments by Types of, the report covers- Adenovirus Fowlpox Virus Attenuated Yellow Fever Vaccinia Virus Vectors Others Market segments by Applications of, the report covers- Hospitals Clinics Others
The report diversifies the global geographical expanse of the market into five prominent regions as:
North America (United States, Canada and Mexico)
Europe (Germany, France, United Kingdom, Russia, Italy, and Rest of Europe)
Asia-Pacific (China, Japan, Korea, India, Southeast Asia, and Australia)
South America (Brazil, Argentina, Colombia, and Rest of South America)
Middle East & Africa (Saudi Arabia, UAE, Egypt, South Africa, and Rest of Middle East & Africa)
Key Elements Discussed In The Report: The report then discusses important dynamics on the business drivers that have a major impact on the performance are given in the report. The business drivers are important to the business operations and financial results of the industry. All the drivers are determined in the research study using market analysis. The report is comprehensive coverage of the existing and potential markets along with their assessment of their competitive position in the changing market scenario. It scrutinizes in-depth global market trends and outlook coupled with the factors driving the global Viral Vector Vaccines market, as well as those hindering it.
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Moreover, the report throws light on the pinpoint analysis of global Viral Vector Vaccines market dynamics. It also measures the sustainable trends and platforms which are the basic roots behind the market growth. With the help of SWOT and Porter’s five analysis, the market has been deeply analyzed. Consumer behavior is assessed with respect to current and upcoming trends. The report takes a detailed note of the major industrial events in past years. These events include several operational business decisions, innovations, mergers, collaborations, major investments, etc.
Customization of the Report: This report can be customized to meet the client’s requirements. Please connect with our sales team ( [email protected]), who will ensure that you get a report that suits your needs. You can also get in touch with our executives on +18488639402 to share your research requirements.
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Contact: Axel Reports Akansha G (Knowledge Partner) Office No- P 221 Pune, Maharashtra 411060 Phone: US +18488639402 Web: https://axelreports.com/
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researchcognizance · 3 years
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Global Viral Vector Vaccines Market Expected to Witness Rapid Expansion by the End of 2027
The recent report on “Global Viral Vector Vaccines Market Report 2021 by Key Players, Types, Applications, Countries, Market Size, Forecast to 2027” offered by Axel Reports, comprises a comprehensive investigation into the geographical landscape, industry size along with the revenue estimation of the business. Additionally, the report also highlights the challenges impeding market growth and expansion strategies employed by leading companies in the “Viral Vector Vaccines Market”.
An exhaustive competition analysis that covers insightful data on industry leaders is intended to help potential market entrants and existing players in competition with the right direction to arrive at their decisions. Market structure analysis discusses in detail Viral Vector Vaccines companies with their profiles, revenue shares in the market, comprehensive portfolio of their offerings, networking and distribution strategies, regional market footprints, and much more.
Download Sample PDF+ All Related Graphs & Charts (Including COVID19 Impact Analysis) @: https://axelreports.com/request-sample/55827
By Market Players: Advanced Bioscience Laboratories Creative Biogene Boehringer Ingelheim Sanofi Brammer Bio Pfizer GE Healthcare
By Type Adenovirus Fowlpox Virus Attenuated Yellow Fever Vaccinia Virus Vectors Others By Application Hospitals Clinics Others
(Note: The sample of this report is updated with COVID-19 impact analysis before delivery)
Key Questions Covered in the Report :
What is the total market value of the Global Viral Vector Vaccines Market report?
What would be the forecast period in the market report?
What is the market value of the Global Viral Vector Vaccines Market in 2021?
What is the Key Industry Leader’s opinion for the Global Viral Vector Vaccines?
Which is the base year calculated in the Global Viral Vector Vaccines Market Report?
What are the key trends in the Global Viral Vector Vaccines Market Report?
What are the market values/growth % of emerging countries?
Which market holds the maximum market share of the Global Viral Vector Vaccines Market?
Some Point from Table of Content:
Market Overview: It includes six chapters, research scope, major manufacturers covered, market segments by type, Viral Vector Vaccines market segments by application, study objectives, and years considered.
Market Landscape: Here, the competition in the Worldwide Viral Vector Vaccines Market is analyzed, by price, revenue, sales, and market share by company, market rate, competitive situations Landscape, and latest trends, merger, expansion, acquisition, and market shares of top companies.
Profiles of Manufacturers: Here, leading players of the global Viral Vector Vaccines market are studied based on sales area, key products, gross margin, revenue, price, and production.
Market Status and Outlook by Region: In this section, the report discusses about gross margin, sales, revenue, production, market share, CAGR, and market size by region. Here, the global Viral Vector Vaccines Market is deeply analysed on the basis of regions and countries such as North America, Europe, China, India, Japan, and the MEA.
Application or End User: This section of the research study shows how different end-user/application segments contribute to the global Viral Vector Vaccines Market.
Market Forecast: Production Side: In this part of the report, the authors have focused on production and production value forecast, key producers forecast, and production and production value forecast by type.
Research Findings and Conclusion: This is one of the last sections of the report where the findings of the analysts and the conclusion of the research study are provided.
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Contact: Axel Reports Akansha G (Knowledge Partner) Office No- B 201 Pune, Maharashtra 411060 Phone: US +18488639402 Web: https://axelreports.com/
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Global Adenovirus Vector Vaccine market- Industry Analysis, Market Size, Share, Trends, Application Analysis, Growth and Forecast 2021-2027: Ken Research
Global Adenovirus Vector Vaccine market- Industry Analysis, Market Size, Share, Trends, Application Analysis, Growth and Forecast 2021-2027: Ken Research
The global Adenovirus Vector Vaccine market is expected to reach USD XX Million by 2027, with a CAGR of XX% from 2020 to 2027, based on HNY Research newly published report. The prime objective of this report “Global Adenovirus Vector Vaccine Industry Research Report 2021 Segmented by Major Market Players, Types, Applications and Countries Forecast to 2027” is to provide the insights on the post…
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leonfrancisblog · 3 years
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Viral Vector and Vaccine Market is Rising exponentially at a Healthy CAGR of 14.50% During the Anticipated Period of 2020 to 2027| Novasep, MerckKGaA, Cobra Biologics Ltd., uniQure N.V., Waisman, Creative-Biogene
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Viral Vector and Vaccine Market size is expected grow at a compound annual growth rate of 14.50% in the forecast period of 2020 to 2027 due to the growing prevalence of disease such as cancer, cardiac diseases, HIV and hemophilia which has raised the need for the development of therapies using viral vector and is primarily driving the market growth rate. Beside this, the presence of untapped medical sector in some regions and rising government initiatives for R&D sector of healthcare sector will produce lucrative opportunities for the growth of the viral vector and vaccine market.
High transfection efficiency, effective gene delivery and stable gene expression have made viral vectors preferred choice for gene transfer and it is evident by increasing clinical trials on viral vector medicated gene therapy. Increasing prevalence of disease such as cardiac diseases, cancer, HIV, Hemophilia has raised need for the development of therapies using viral vector whereas advancement in technology to manufacture viral vector is the key factor driving market growth. Moreover rising adoption of viral vectors by biopharmaceutical industries and increasing cost effective treatments are factor propelling market demand whereas lack of skilled professionals and high cost are factors restraining market growth. However untapped medical sector in some regions and increasing government initiatives for R&D sector of healthcare sector will produce lucrative opportunities in coming years.
Global Viral Vector & Vaccine Market By Type (Adenovirus, Retrovirus, Plasmid DNA, AAV, Lentivirus, Others), Workflow Upstream Processing, Downstream Processing, Application (Antisense & RNAi, Gene Therapy, Cell Therapy, Vaccinology), Disease (Cancer, Genetic Disorders, Infectious Diseases, Others), End Use (Pharmaceutical and Biopharmaceutical Companies, Research Institutes), Country (U.S., Canada, Mexico, Germany, Italy, U.K., France, Spain, Netherlands, Belgium, Switzerland, Turkey, Russia, Rest of Europe, Japan, China, India, South Korea, Australia, Singapore, Malaysia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific, Brazil, Argentina, Rest of South America, South Africa, Saudi Arabia, UAE, Egypt, Israel, Rest of Middle East & Africa) Industry Trends and Forecast to 2027 This viral vector & vaccine market report provides details of new recent developments, trade regulations, import export analysis, production analysis, value chain optimization, market share, impact of domestic and localised market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographic expansions, technological innovations in the market. To gain more info on viral vector & vaccine market contact us for an Analyst Brief, our team will help you take an informed market decision to achieve market growth.
Get Sample PDF of Viral Vector and Vaccine Market Report (including COVID19 Impact Analysis) @ https://www.databridgemarketresearch.com/request-a-sample/?dbmr=global-viral-vector-and-vaccine-market
Viral Vector and Vaccine Market Scope:
Viral vector and vaccine market is segmented on the basis of countries into the U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa(MEA), Brazil, Argentina and Rest of South America as part of South America.
All country based analysis of viral vector and vaccine market is further analyzed based on maximum granularity into further segmentation. Based on type, the viral vector & vaccine market is segmented into adenovirus, retrovirus, plasmid DNA, AAV, lentivirus, and others. Based on workflow, the viral vector and vaccine market is segmented into upstream processing, downstream processing. Based on application, the viral vector & vaccine market is segmented into antisense & RNAi, gene therapy, cell therapy, and vaccinology. On the basis of disease, viral vector and vaccine market is segmented into cancer, genetic disorders, infectious diseases, and others. Viral vector and vaccine market has also been segmented based on end use into pharmaceutical and biopharmaceutical companies, and research institutes.
Viral vectors are one of the promising tools that are used for gene therapy and vaccines. Viral vector-based vaccines can improve immunogenicity without an adjuvant and encourage a robust cytotoxic T lymphocyte response to eradicate virus infected cells.
Key Market Competitors Covered in the report:
Novasep, MerckKGaA, Cobra Biologics Ltd., uniQure N.V., Waisman, Creative-Biogene, Aldevron, Addgene, Oxford Biomedica, Thermo Fisher Scientific Inc, Cell Therapy Catapult Limited Eurogentec, Fujifilm, Spark Therapeutics Inc. DBMR analysts understand competitive strengths and provide competitive analysis for each competitor separately.
Key Pointers Covered in the Viral Vector Market Size:
Market New Sales Volumes
Market Replacement Sales Volumes
Market Installed Base
Market By Brands
Market Procedure Volumes
Market Product Price Analysis
Market Healthcare Outcomes
Market Cost of Care Analysis
Market Regulatory Framework and Changes
Prices and Reimbursement Analysis
Market Shares in Different Regions
Recent Developments for Market Competitors
Market Upcoming Applications
Market Innovators Study
MAJOR TOC OF THE REPORT:
Chapter One: Viral Vector and Vaccine Market Overview
Chapter Two: Manufacturers Profiles
Chapter Three: Viral Vector and Vaccine Market Competition, by Players
Chapter Four: Viral Vector and Vaccine Market Size by Regions
Chapter Five: Viral Vector and Vaccine Market Revenue by Countries
Chapter Six: Viral Vector and Vaccine Market Revenue by Type
Chapter Seven: Viral Vector and Vaccine Market Revenue by Application
Chapter Eight: Viral Vector and Vaccine Market Revenue by Industries
Chapter Nine: Viral Vector and Vaccine Market Revenue by Deployment Model
Chapter Ten: Viral Vector and Vaccine Market Revenue by End User
Get Detail TOC@ https://www.databridgemarketresearch.com/toc/?dbmr=global-viral-vector-and-vaccine-market  
Key Report Highlights:
Comprehensive pricing analysis based on different product types and regional segments
Market size data in terms of revenue and sales volume
Deep insights about regulatory and investment scenarios of the global Information Rights Management Market
Analysis of market effect factors and their impact on the forecast and outlook of the global Information Rights Management Market
The detailed assessment of the vendor landscape and leading companies to help understand the level of competition in the global Information Rights Management Market
A roadmap of growth opportunities available in the Global Information Rights Management Market with the identification of key factors
The exhaustive analysis of various trends of the Global Information Rights Management Market to help identify market developments
Key Questions Answered in Report:
What is the key to the Information Rights Management Market?
What will the Information Rights Management Market Demand and what will be Growth?
What are the latest opportunities for Information Rights Management Market in the future?
What are the strengths of the key players?
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bbcbreakingnews · 4 years
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Sputnik’s ‘efficacy at 95%’, to be cheaper than US vaccines
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MUMBAI: Russia’s Sputnik V Covid-19 vaccine, that reported an efficacy of over 95%, will be twice as cheap as those by Pfizer and Moderna with similar positive results. Sputnik V, developed by Gamaleya Institute and RDIF (Russian Direct Investment Fund), will be priced under $20 per person for the two doses in global markets, including India, and may be available here by February. The vaccine is still to undergo trials in India and will be manufactured by domestic companies. Hyderabad-based Dr Reddy’s and RDIF have entered into a partnership to conduct clinical trials and distribute it in India. Though the vaccine has a price advantage against the above two firms, there could be a challenge in its distribution as it requires a specialised cooling chain, experts say. The efficacy of the Sputnik V vaccine is 91.4%, based on the second analysis of interim data obtained 28 days after administering the first dose (7 days after the second dose). Preliminary data obtained 42 days after the first dose indicates an efficacy above 95%, a statement said. Sputnik V, a two-dose vaccine on the human adenoviral vector platform, will soon initiate Phase II clinical trials on 100 subjects in India, while Phase III trials will involve 1,500 participants. In October, Dr Reddy’s and RDIF received approval from the Drugs Controller General of India to conduct adaptive phase II/III human clinical trials for the vaccine in India. As part of the partnership, RDIF will supply 100 million doses of the vaccine to Dr Reddy’s. The first international deliveries of the Russian Sputnik V vaccine will be made in January 2021 based on the existing partnerships with foreign manufacturers, the statement adds. Details about the vaccine, trials and manufacturers in India are still sketchy. “There are two forms of the vaccine, one of which requires -18°C (liquid) and must be transported in special refrigerators. Second form is lyophilised (freeze-dry) and can be stored at +2 to -8°C. We expect that the freeze-dry version will be supplied in large quantities to many countries including India in February,” a RDIF spokesperson told TOI. “The uniqueness of the vaccine lies in the use of two different vectors based on the human adenovirus, which allows for a stronger and longer-term immune response as compared to vaccines using one and the same vector for two doses,” the statement added. The existing agreements between RDIF and leading foreign pharmaceutical companies allow the Sputnik V vaccine to be produced abroad for 500 million people per year, starting from 2021.
source https://bbcbreakingnews.com/2020/11/25/sputniks-efficacy-at-95-to-be-cheaper-than-us-vaccines/
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pharmaphorumuk · 4 years
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Russian Sputnik COVID-19 vaccine ‘will cost less than $10 a dose’
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The developer of Russia’s COVID-19 vaccine Sputnik V has pledged to make it available for less than $10 per dose – or $20 per two-dose course – on the same day as revealing new clinical data with the shot.
Sputnik V’s efficacy has remained high at 91.4% according to the latest analysis, which comes from almost 19,000 subjects who were assessed seven days after the second dose of the vaccine, administered 28 days after the first.
Preliminary data from a smaller group of patients 21 days after the second shot suggests an efficacy of 95%, according to a press release from the Gamaleya Institute and Russian Direct Investment Fund (RDIF).
That puts the efficacy of the adenovirus-based vaccine ahead the 70% overall efficacy seen with AstraZeneca/University of Oxford’s AZD1222 jab – also based on an adenoviral vector – although AZ said yesterday there was a protective efficacy of 90% among patients receiving the vaccine as a half dose, followed by a full dose at least one month later.
AZ’s trial also had a higher number of confirmed cases of COVID-19 to power the analysis, at 131 cases, while there were 39 cases in the Russian study by the latest data cutoff. The next analysis for Sputnik V will be made when there are 78 confirmed coronavirus cases.
Sputnik V’s developers say its high level of efficacy comes from the use of two different adenoviral vectors which “allows for a stronger and longer-term immune response as compared to the vaccines using one and the same vector for two doses.”
At the moment scientists only have the top-line data from press releases to go on so it is impossible to make any judgments about the relative efficacy of the two vaccines, or indeed the two mRNA-based shots from Pfizer/BioNTech and Moderna that have also shown efficacy rates above 90% in clinical trials.
The RDIF has echoed the position voiced by AZ that its adenoviral vaccine will be cheaper than the mRNA shots – by two to three times – and also has the advantage of being stored using regular refrigeration temperature of +2 to +8 degrees Celsius.
Pfizer and Moderna’s vaccines require much lower temperatures to prevent their active ingredients from breaking down.
“Such a regime enables the distribution of the vaccine in international markets, as well as expanding its use in hard-to-reach regions, including areas with tropical climates,” it said.
Russia will provide Sputnik V to its domestic population free of charge, so the $10 per dose price applies to international markets.
Capacity to make the vaccine is currently enough to immunise 500 million people per year, and the first international deliveries will be made to customers in January. Other orders will start to be fulfilled from March.
Russia approved Sputnik V in August, making it the first coronavirus vaccine worldwide to be licensed worldwide.
So far it has accepted orders for 1.2 billion doses from more than 50 countries, including Brazil, India, Mexico and Hungary – the latter deal reportedly putting the EU member state at odds with the European Commission as Sputnik V hasn’t yet been approved by the EMA.
The post Russian Sputnik COVID-19 vaccine ‘will cost less than $10 a dose’ appeared first on .
from https://pharmaphorum.com/news/russian-sputnik-covid-19-vaccine-will-cost-less-than-10-a-dose/
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dailynewswebsite · 4 years
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COVID-19 vaccine update: Pfizer may be the frontrunner, but Canada has hedged its bets
Folks sporting masks stroll in entrance of Pfizer's headquarters in New York Metropolis. Pfizer and BioNtech are on observe with a vaccine that’s 90 per cent efficient, say preliminary outcomes, however they aren’t the one ones within the race. AP Photograph/Bebeto Matthews
Pfizer and BioNTech have shocked the world, and given it hope, with the preliminary outcomes of the Part Three scientific trial of their coronavirus vaccine.
They introduced on Nov. 9 that the early evaluation of the info from the Part Three scientific trial, which continues to be ongoing, confirmed the vaccine was 90 per cent efficient. The unexpectedly excessive determine nonetheless must be confirmed in bigger numbers and over time. The vaccine is easy to fabricate, however its storage is extra advanced (the vaccine have to be stored at very low temperatures). Massive-scale manufacturing is predicted to start shortly.
Laboratories all over the world are in a race to supply a COVID-19 vaccine. Whereas the end line is now in sight for Pfizer and BioNTech, the World Well being Group (WHO) lists 202 vaccine candidates, 47 of that are in human trials.
Canada has not put all its eggs in a single basket in its plan to guard Canadians from the novel coronavirus. Along with Pfizer and BioNTech, it has signed six different contracts: Moderna, Sanofi and GlaxoSmithKline, Johnson & Johnson, Novavax, AstraZeneca and Medicago. Canada just lately introduced it had reserved 56 million further doses of vaccine from Pfizer and BioNTech, on high of the 20 million doses it had already bought, bringing its order to 76 million.
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Overview of vaccine varieties in scientific trials, primarily based on WHO Nov. Three replace. (World Well being Group)
Canada has secured entry to a complete of 414 million doses of COVID-19 vaccines from completely different sources. Extra importantly, Canada has ensured that it has diversified the varieties of vaccines it is going to have.
Scientists are utilizing completely different platforms to develop COVID-19 vaccines. Some vaccine candidates in scientific trials exploit mechanisms already utilized in different vaccines. Others are primarily based on revolutionary approaches which have by no means been examined earlier than. Right here is an summary of the several types of vaccines.
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The platforms used for COVID-19 vaccine candidates in scientific trials. Methods already in use are proven within the crimson field whereas novel approaches are proven within the inexperienced field. Pictures created utilizing Mol* (Almo and al. (2020) PBD ID 6X6P. Determine created with BioRender.com
Inactivated vaccines
Inactivated vaccines have been in use for the reason that 1880s. The viruses in these vaccines have been rendered inactive by chemical therapy, as with SARS-CoV-2 candidate vaccines, or by bodily therapy.
With any such vaccine, the immune system encounters the virus in its entirety. It could possibly mount a defence when it detects the viral spike protein (additionally referred to as spicule or S-protein), envelope and nucleoprotein.
Presently, seven inactivated vaccine candidates are being examined in people. Of those, three are in Part Three scientific trials. Not like Part 1 and Part 2, that are used to guage a vaccine’s tolerability, security and talent to induce an immune response, a Part Three scientific trial permits scientists to check its efficacy.
Recombinant proteins
Recombinant protein vaccines fall into two classes: subunit and virus-like particle vaccines.
For subunit protein vaccines, a viral protein is produced in massive portions in a residing “manufacturing facility,” resembling a bacterium, plant, mammalian or insect cell. When the viral protein is offered to the immune system, it triggers a response.
The 13 subunit vaccine candidates at the moment in Part 1, 2 or Three scientific trials are composed of both all the spike protein or a particular portion of the spike protein referred to as the ‘receptor binding area’.
Virus-like particle vaccines are composed of a set of viral proteins that mimic the form of the virus. This particle “pseudo-virus” is an empty shell, devoid of genetic materials and non-infectious, however this doesn’t forestall the immune system from recognizing it.
Viral vector vaccines
This method is predicated on utilizing a virus that’s non-pathogenic or of little hazard to people. Within the case of the 12 vaccine candidates of this kind at the moment being studied in people, the viral vectors are largely adenoviruses. They symbolize a big group of viruses that may trigger colds and conjunctivitis, amongst different signs.
Used as Trojan horses, these viruses are modified to specific the SARS-CoV-2 spike protein following vaccination. Viral vector vaccines are a current technique, however had been used within the growth of the Ebola virus vaccine.
RNA and DNA vaccines
Regardless of variations of their composition, DNA and mRNA (messenger RNA) each include genetic data for protein manufacturing. Whereas an RNA molecule can instantly produce that data, DNA requires an intermediate transcription step.
RNA or DNA vaccine candidates differ from different methods in two methods. First, it’s a novel technique: there isn’t any RNA or DNA vaccine available on the market. Second, they’re the one vaccine candidates composed solely of genetic materials.
Within the case of RNA vaccines, messenger RNA molecules are wrapped in lipid nanoparticles. As soon as the vaccine is injected, the RNA serves as a template for the physique’s cells to supply a viral protein — the spike protein, to be exact.
DNA vaccines, then again, are made up of a round DNA (referred to as a plasmid). This DNA will probably be transcribed into RNA, which can once more function a template.
Six RNA vaccine candidates are at the moment being examined in people, two of that are in Part 3. The 5 DNA vaccine candidates are in Part 1 and a pair of scientific trials.
Canada within the vaccine race
The next is an summary of every firm that has an settlement with the federal authorities, the kind of vaccine in growth and the variety of doses reserved by Canada.
Pfizer/BioNTech: 76 million doses reserved
BioNTech, in Germany, and Pfizer, in the USA, are collectively growing an RNA vaccine. This candidate encodes for the manufacture of the spike protein.
The Part Three scientific research is constant with greater than 43,000 sufferers within the U.S., Argentina, Brazil, Germany, Turkey and South Africa. The vaccine is reported to be greater than 90 per cent efficient and has not brought on any critical side-effects.
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An outline of Pfizer Manufacturing Belgium in Puurs, Belgium. Pfizer introduced that preliminary outcomes of its COVID-19 vaccine present 90 per cent efficacy. (AP Photograph/Virginia Mayo)
Regardless of these encouraging preliminary outcomes, Pfizer and BioNTech haven’t but crossed the end line. Detailed knowledge haven’t been revealed and questions stay, together with the age and danger components of the vaccinated people and the period of safety. The scientific trial is ongoing and extra knowledge will probably be analyzed.
Moderna: 56 million doses reserved
The vaccine candidate of Moderna, a U.S.-based biotechnology firm, is an RNA vaccine. As soon as injected, it permits the expression of the spike protein. Presently in Part Three scientific trials, the vaccine is being examined in 30,000 people in numerous areas throughout the USA.
Johnson & Johnson: 38 million doses reserved
Johnson & Johnson’s candidate is a viral vector vaccine composed of a human adenovirus that has been modified to render it incapable of multiplying, however able to expressing the SARS-CoV-2 spike protein. The Part Three scientific trial, which started in September 2020, is going down in a number of nations and can contain 60,000 individuals.
AstraZeneca/College of Oxford: 20 million doses reserved
Oxford College is partnering with AstraZeneca on a viral vector vaccine. The vaccine candidate consists of a modified chimpanzee adenovirus that expresses the spike protein. It’s in Part Three scientific trials.
Novavax: 76 million doses reserved
The vaccine candidate of Novavax, a U.S. firm, is predicated on the recombinant protein technique. It’s composed of the spike protein and an adjuvant, a booster utilized in vaccines to extend the immune response. The Part Three scientific trial started in September 2020 and includes 10,000 individuals in the UK.
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Some examples of commercially obtainable vaccines that use the several types of vaccines described. Created from Servier Medical artwork (http://servier.com/Powerpoint-image-bank). Servier Medical Artwork by Servier is licensed beneath a Inventive Commons Attribution 3.0-Unported License
Sanofi/GSK: 72 million doses reserved
The candidate from the French firm Sanofi and the British large GlaxoSmithKline (GSK) consists of an adjuvant and recombinant model of the spike protein, produced in a residing manufacturing facility (baculoviruses). Part 1 and a pair of scientific trials are at the moment testing its security, tolerability and talent to induce an immune response.
Medicago: 76 million doses reserved
Developed by the Québec-based firm Medicago, this vaccine candidate consists of virus-like particles. These are produced in crops contaminated with micro organism which have been genetically modified to supply a number of SARS-CoV-2 proteins. These crops thus turn into manufacturing crops.
Researchers can extract the particles from the leaves and purify them. Medicago’s vaccine candidate is at the moment in Part 1 scientific trials and outcomes are additionally promising.
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Aïssatou Aïcha Sow receives a scholarship financed by the analysis funds of her analysis director and by Institut nationwide de la recherche scientifique (INRS). She is a member of the Canadian Virological Society.
from Growth News https://growthnews.in/covid-19-vaccine-update-pfizer-may-be-the-frontrunner-but-canada-has-hedged-its-bets/ via https://growthnews.in
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sandlerresearch · 4 years
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Coronavirus Disease Vaccines (COVID-19 Vaccines) published on
https://www.sandlerresearch.org/coronavirus-disease-vaccines-covid-19-vaccines.html
Coronavirus Disease Vaccines (COVID-19 Vaccines)
Coronavirus Disease Vaccines (COVID-19 Vaccines)
Summary
The sprint to advance a COVID-19 vaccine is hotly contested. More than 100 vaccines are in preclinical testing, according to GlobalData, while 23 companies have moved their candidates into clinical trials. Broadly, some eight different vaccine technologies are in clinical trials: mRNA, DNA plasmid, protein subunit, adenovirus-vectored, measles-vectored, vesicular stomatitis virus-vectored, adenovirus associated-vectored and inactivated virus vaccines. Seven companies have planned or ongoing Phase II/III studies: AstraZeneca, Inovio, Moderna, Novavax, Pfizer/BioNtech, Sinopharm and Sinovac
Key Highlights
– Sixteen catalysts highlighted – Eight vaccine technologies in clinical trials discussed – Seven companies with planned or ongoing Phase II/III studies plus others in earlier-stage development analyzed – Five investigative articles on trial design requirements and launch considerations with an early EUA – Five to 12 experts cited per article
Scope
– Snapshot of upcoming high-impact, catalytic events for COVID-19 vaccines – Insights investigative journalism related to COVID-19 vaccine development – Exclusive analysis of various vaccine technologies’ prospects – Considerations for trial protocols and approvals
Reasons to Buy
– Stay ahead of pipeline developments for COVID-19 vaccines – Obtain a snapshot of future, key clinical trial events – Access qualitative asset analysis based on talking to 5-12 KOLs about various vaccines in clinical trials – Leverage investigative journalism content on prospects for vaccine approvals and market uptake
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rohinic123-blog · 4 years
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COVID-19 Vaccine Pipeline Market Future Growth Analysis, Demand and Supply Analysis and COVID19 Impact Analysis Covered 2020 - 2030
COVID-19 Vaccine Pipeline: Introduction
COVID-19 is an infectious disease caused by the coronavirus. COVID-19 began its outbreak in Wuhan, China in December 2019. The World Health Organization (WHO) declared COVID-19 as Public Health Emergency of International Concern on January 30, 2020.
COVID-19 is spreading rapidly across the globe and almost every country has reported notable number of cases as well as death due to this this infection
Till date, the U.S. has recorded highest number of COVID-19 cases with count of more than one million active cases and more than 60,000 deaths. In Europe, more than 1.4 million active cases of COVID-19 have been reported as of April 30, 2020 with Italy being the worst affected country in the region. Italy has reported around 200,000 Covid-19 cases and more than 27,000 deaths.
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The most common symptoms associated with COVID-19 are fever, dry cough, tiredness, aches and pains, nasal congestion, sore throat; and diarrhea. In the beginning stages of the COVID-19 infections, the symptoms are very mild. According to the WHO, 1 out of every 5 COVID-19 patients becomes seriously ill and faces breathing problem.
No perfect treatment or cure is available to treat the disease till date and lots of research and development activities are being carried out by leading players operating in the biopharmaceutical market place and all are expecting some positive outcomes very soon
The WHO has facilitated and accelerated efforts on the development of COVID-19 vaccine on such a scale that was not ever seen before in history
Healthcare experts estimate that the fast tracked vaccine development process could take around 12 to 18 months to successfully reach the market
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COVID-19 Vaccine Pipeline: Clinical Trial Phase 2/3
The University of Melbourne and Murdoch Children’s Research Institute are testing Bacillus Calmette-Guerin (BCG) live-attenuated vaccine for COVID-19. According to a research article published in MedRxIV in April 2020, the people in countries with BCG vaccination program at childhood are less virulent to COVID-19 than that of people in countries without BCG vaccination program.
Researchers at Radboud University Medical Center (The Netherlands) have launched the phase-3 BCG-CORONA trial on March 31, 2020 and plan to enroll 1,500 healthcare workers to receive the BCG vaccine or placebo
Clinical Trial Phase 2
China-based biotech company Sinovac Biotech is developing COVID-19 vaccine candidate PiCoVacc. The company has claimed to have successfully tested the vaccine against COVID-19 in monkeys. The company is in talks with the World Health Organization to launch the phase-3 clinical trials in the region where the COVID-19 cases are rapidly spreading.
Massachusetts-based biotech company Moderna has developed the mRNA-1273 COVID-19 vaccine candidate. The mRNA-1273 is currently in phase-2 stage of clinical trial pipeline study and the USFDA has awarded the fast track designation for this candidate.
The China National Pharmaceutical Group (Sinopharm) is developing the inactivated vaccine candidate against COVID-19. The vaccine candidate has received the approval from the National Medical Products Administration and is currently in phase-2 of clinical trial pipeline studies.
Expanding Operations in Future? To Get the Perfect Launch Ask for a Custom COVID-19 Vaccine Pipeline Market Report
Clinical Trial Phase 1
China-based biotechnology company CanSino Biologics has used the adenovirus type 5 vector (Ad5) to develop novel COVID-19 vaccine. The preliminary safety data from phase-1 clinical trials is positive and it allowed the company to plan for phase-2 clinical trial studies.
The Oxford university’s Jenner Institute in collaboration with AstraZeneca is developing the ‘ChAdOx1 nCoV-19' coronavirus vaccine. The vaccine has shown the positive results on six rhesus macaque monkeys in March 2020. After the positive results from the initial trials on macaque monkey, the Oxford’s team is planning to test the vaccine on 6,000 people by the end of May 2020. If the clinical trials are successful in humans, then few million doses of the vaccine would be available by the end of September 2020.
The Serum Institute of India has planned to collaborate with Oxford University for the manufacture of vaccine if clinical trials are successful. The Serum Institute of India can produce 5 million doses of vaccine per month for the first 6 months and after that, the company can scale up to 10 million doses per month.
Inovio Pharmaceuticals is developing DNA vaccine INO-4800 against COVID-19. The Inovio Pharmaceuticals and the International Vaccine Institute (IVI) in association with Korea National Institute of Health (KNIH) are conducting phase 1/2 clinical trials in Korea.
Pfizer Inc. and BioNTech have collaborated to develop COVID-19 vaccine candidate BNT 162. The BNT-62 is currently under phase 1/2 clinical trial study. The human trials are also started with BNT 162 in the U.S.
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Pre-clinical
A lot of companies are developing COVID-19 vaccine candidates in preclinical studies. Some of companies having vaccine candidates in preclinical studies are Novavax, CureVac, Generex Biotechnology, Vaxart, Medicago, Takis Biotech, Altimmune, and Johnson and Johnson.
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cmfelatestarticle · 5 years
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Cancer Gene Therapy Market is predicted to reach USD 16,494.66 million by 2030
Cancer Gene Therapy Market is predicted to reach USD 16,494.66 million by 2030The Global Cancer Gene Therapy Market held USD 558.24 million in 2018 and is predicted to reach USD 16,494.66 million by 2030 with a CAGR of 32.6% from 2019-2030
Read Report Overview @
https://www.nextmsc.com/report/cancer-gene-therapy-market
Cancer gene therapy is a technique of healing distribution of genetic material into a patient's cells as a drug to treat disease and compensate for abnormal genes or to make a beneficial protein. The cancer cells can modify themselves in numerous genetic factors that make them further divide into very often and form a tumor.
During the treatment of cancer, the genes are replaced to fight against cancer-causing tumor cells. Gene therapy is an effective treatment for chronic diseases as they cause least side effects with maximum efficacy. The innovation in the gene therapy with better success rate and increasing prevalence of cancer worldwide is generating new opportunity for cancer gene therapy market.
The cancer gene therapy market size is growing owing to factors including increased prevalence of cancer, the growing popularity of DNA vaccines. Furthermore, increasing funding for R&D activities for cancer gene therapy majorly driven the cancer gene therapy market. Further, ethical acceptance of gene therapy for treatment of diseases, and favorable government regulations growing has further supplemented the market growth. However, the high cost of gene therapy treatment and unwanted immune responses is hampering the growth of the cancer gene therapy market. The rapid technological advancements and untapped markets in developing economies will open new opportunities for cancer gene therapy market share in the future.
The cancer gene therapy market is segmented on the basis of therapy, end-user, and geography. On the basis of therapy, the cancer gene therapy market is classified into gene induced immunotherapy, gene transfer, and oncolytic virotherapy. The gene induced immunotherapy is further sub-segmented into the delivery of cytokines gene and delivery of tumor antigen gene. The gene transfer is further sub-segmented into naked/plasmid vectors, sonoportion, magnetofection, electroporation, and gene gun. The oncolytic virotherapy segment is further sub-segmented into adenovirus, lentivirus, vaccinia virus, herpes simplex virus, alpha virus, retro virus, adeno associated virus, simian virus, and others. On the basis of application, the market is divided into hospitals, diagnostics centers, and research institutes. Geographic breakdown and analysis of each of the aforesaid segments include regions comprising North America, Europe, Asia-Pacific, and LAMEA.
North America denotes a higher adoption of the cancer gene therapy and is anticipated to hold the highest market share during the forecast period. This is attributable to the factors including enhanced developments in healthcare, a large number of aging population, technological advancement, and high consumer awareness.
It is expected that the emerging economies, specifically in the Asia-Pacific region would witness increasing market size owing to improvement in a healthcare facility, increasing government initiatives, and increasing the affordability for advanced treatment due to increasing disposable income.
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Comprehensive competitive analysis and profiles of the major market players such as Bluebird bio, Inc., Merck, Adaptimmune, GlaxoSmithKline, BioCancell, Shenzhen SiBiono GeneTech, SynerGene Therapeutics, Celgene, Shanghai Sunway Biotech, OncoGenex Pharmaceuticals, and among others are provided in the cancer gene therapy market report.
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Global Viral Vector Vaccines Market 2019 | Manufacturers In-Depth Analysis Report to 2024
The latest trending report Global Viral Vector Vaccines Market 2019-2024 added by DecisionDatabases.com
Viral vector vaccines combine many of the positive qualities of DNA vaccines with those of live attenuated vaccines.
The worldwide market for Viral Vector Vaccines is expected to grow at a CAGR of roughly xx% over the next five years, will reach xx million US$ in 2024, from xx million US$ in 2019.
This report focuses on the Viral Vector Vaccines in global market, especially in North America, Europe and Asia-Pacific, South America, Middle East and Africa. This report categorizes the market based on manufacturers, regions, type and application.
Browse the complete report and table of contents @ https://www.decisiondatabases.com/ip/40542-viral-vector-vaccines-industry-analysis-report
Market Segment by Manufacturers, this report covers
·          Advanced Bioscience Laboratories
·          Boehringer Ingelheim
·          Brammer Bio
·          Creative Biogene
·          GE Healthcare
·          Pfizer
·          Sanofi
Market Segment by Regions, regional analysis covers
·          North America (United States, Canada and Mexico)
·          Europe (Germany, France, UK, Russia and Italy)
·          Asia-Pacific (China, Japan, Korea, India and Southeast Asia)
·          South America (Brazil, Argentina, Colombia etc.)
·          Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)
Market Segment by Type, covers
·          Adenovirus
·          Fowlpox Virus
·          Attenuated Yellow Fever
·          Vaccinia Virus Vectors
·          Others
Market Segment by Applications, can be divided into
·          Hospitals
·          Clinics
·          Others
Download Free Sample Report of Global Viral Vector Vaccines Market @ https://www.decisiondatabases.com/contact/download-sample-40542
The content of the study subjects, includes a total of 15 chapters: Chapter 1, to describe Viral Vector Vaccines product scope, market overview, market opportunities, market driving force and market risks. Chapter 2, to profile the top manufacturers of Viral Vector Vaccines, with price, sales, revenue and global market share of Viral Vector Vaccines in 2017 and 2018. Chapter 3, the Viral Vector Vaccines competitive situation, sales, revenue and global market share of top manufacturers are analyzed emphatically by landscape contrast. Chapter 4, the Viral Vector Vaccines breakdown data are shown at the regional level, to show the sales, revenue and growth by regions, from 2014 to 2019. Chapter 5, 6, 7, 8 and 9, to break the sales data at the country level, with sales, revenue and market share for key countries in the world, from 2014 to 2019. Chapter 10 and 11, to segment the sales by type and application, with sales market share and growth rate by type, application, from 2014 to 2019. Chapter 12, Viral Vector Vaccines market forecast, by regions, type and application, with sales and revenue, from 2019 to 2024. Chapter 13, 14 and 15, to describe Viral Vector Vaccines sales channel, distributors, customers, research findings and conclusion, appendix and data source.
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