#fat cells

[bpod-bpod]

Fat Freeing

Mobilising stored fat from white fat tissue is controlled by the influence of transcription factor ZFP189 on the accessibility and therefore expression of the gene encoding an enzyme PDE1B2 – insight for potential obesity management strategies

Read the published research article here

Image from work by Alison C. Ludzki and colleagues

Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden

Image originally published with a Creative Commons Attribution 4.0 International (CC BY-NC 4.0)

Published in Science Advances, January 2024

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[bits-of-wit]

[fiercemillennial]

Fat Cells: A Love-Hate Relationship

Ever wondered what really happens to those stubborn fat cells when you lose weight? It's not as simple as you might think. Let's dive into the science behind it and debunk some common myths. #FierceWellness #FierceMillennial

Why Losing Weight Isn’t Always as Simple as Shrinking Cells When You Lose Weight, Your Fat Cells Don’t Just Let Go of Fat Ever felt like those pesky fat cells are holding onto your weight for dear life? You’re not alone. Many people have this misconception that when they lose weight, their fat cells simply shrink and disappear. But the truth is, it’s not quite that straightforward. So, what…

[listentoace]

The Cell

Listen here [08:23 NSFW]

You have been kidnapped and wake up in a small cell, maybe 12m²/130f². You see a few cameras on the ceiling, a toilet and shower in the corner, and a thick metal door locking you inside. But one thing stands out, which is a chair in front of a wall of 25 screens with a tube dangling from the ceiling above. You shift a little on your bed, noticing that you're fully naked and that your ankle is chained to the room center. You hear a loud "clank" sound and see the handle of the door moving. A tall man enters your dark cell, you can't fully see his face, but his wide grin sends shivers down your spine. "Hello there, little one.", he says as he walks up to you. Your heart is racing and you begin to sweat. "Let's get you in place, shall we?", he says, grabs you by your collar and drags you to the chair, the chain rattles and scratches over the concrete floor. As he sits you down, he immediately fastens your wrists and legs to the chair, making it impossible for you to move. You feel a nudge with knobs pushing against your pussy.

You notice another display, right above the 5x5 screen wall, which lights up and reads 163lbs. "Already a bit chubby, huh? Well, you'll soon be in heaven.", he says and pats your belly, causing the number on the display to jump around a little before it settles down at 163lbs again. His wide and warm hands glide over your body, pinching a few folds and rolls, before he pulls out his phone. Shortly after, you hear a humming noise and the tube lowers from the ceiling. He grabs it, straps it around your head and forces the tube into your mouth. The fit is tight enough that you won't be able to spill, yet not uncomfortable. The thick tube dangles in front of your face, blocking a little of your vision. Next, all the screens light up, shortly after displaying 25 different loops of captioned porn, with text reading from "good girls obey" to "your weight = your value", and even just single-word loops like "drink, drink, drink, ...". As you see this, your heart begins to race immediately, fearing the worst.

"You'll be sitting here for 14 hours a day from now on. You get a 5-minute break every hour to go to the bathroom. You'll be filmed and live streamed at all times, so feel free to say hi to the viewers.", he explains. There is a camera right in front of you, slightly below in front of you, one above you, one at a 45° angle, one at a 90° angle, and more in the cell's corners. You're already struggling to pay attention with all the porn in front of you. "You'll be unlocked automatically and a timer will appear on the ceiling display where you can currently see your weight. If you don't sit back down in time, the collar will start shocking you, just so you're warned.", he continues. You can feel your heart rate rise, it hasn't been this high in weeks, if not months. The porn you're forced to watch doesn't help and only makes your heart beat faster. "Good Girls get fat".

"You feel that nudge?", he asks and looks at you with a sinister grin. You nod, feeling the nudge against your pussy, which is already soaked. It stats to vibrate slowly, which you didn't see coming. It sends shivers down your spine and you already notice how your mind is starting to become blank. Your eyes constantly jump around between the screens, looking at cocks thrusting into pussies, cum shots, bouncing tits, jiggling asses, all at the same time on 25 screens. You're overwhelmed and don't know where to look. Everywhere are captions, heavily triggering you and making your pussy throb even more. "Well then, I guess you'll figure the rest out soon enough...", he finishes, gives your belly another pat, gropes your tits, and then just leaves the cell. Him leaving makes you panic slightly, but then the speakers turn on, playing some hypno track of fucking sounds, moaning, and several voices telling you to drink, give in, goon, get fatter, indulge, surrender, obey, serve, fatten, throb, grind, grow. You struggle not to lose the last bit of your mind, as you're bombarded by porn, captions, and the hypno audio track.

You hear a "ding" sound, and shortly after, a sweet, creamy liquid flows into your mouth. The second the sugar hits your tongue, the vibrator fires up, sending shockwaves of pleasure through your body. "Drink, drink, drink, drink, ..." pops up everywhere on the screens, conveniently censoring all the cocks, pussies, tits, and butts. The hypno track tells you in echoing voices that "good girls drink up", "it tastes soooo good", and "every gulp makes you even wetter". You hate how good the shake tastes, actually offering a full, sweet flavor that makes you want to just keep drinking. Before you know it, you've downed your first liter, the ceiling display reads 165lbs. The shake stops and the vibrator slows down again. Little do you know that people online can spend their money to both turn on your vibrator or to force more calories down your throat.

Before you know it, half an hour has gone by. Your pussy drips, your thighs are sticky and the sweat is running down your skin. Your mind is completely empty now, your eyes jump between the many screens of porn, frustrated that 9/10 times the intimate areas are censored by captions but every time they're not, you feel a rush, as you see a pair of tits bouncing up and down while she's being fucked. You never know when the next "ding" comes, but as soon as it does, you feel immense pleasure and always get very close to cumming. Unfortunately, you can't manage to get over the edge, but that might be by design. Another half hour later, the porn pauses. At first you don't get why, but it seems to be your break. The metal restraints open, freeing your ankles and wrists. You look up to the ceiling display, which reads 168lbs.

The first thing you do once your hands are free is rubbing your pussy. You just need to cum, after being stimulated like this for an hour. But the second you touch your pussy, your collar gives you a mild shock. "No touching", echoes from the speakers. You try getting up from the chair to go to the toilet, your legs are shaky and weak. You can barely walk, but luckily there is a railing mounted to the wall to help you get there. This will especially come in handy once you're a couple hundred pounds heavier. After finishing, you see the timer ticking, "02:13", "02:12", "02:11", so you waddle back to the chair and sit down again, the restraints automatically fasten. This will be your life from now on.

--- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---

Thank you very much for reading! Depending on how you like this, I might turn it into a much longer, full story, which I'll also be reading/recording audios for. To ensure my efforts are worth it, please write a comment or dm about whether or not you want more of this. Thank you very much!

[n0rtist]

Here’s the latest Stemae, featured in my previous video.

Stemotl (Chroma): While Stemotls are not native to this region, they have been popular in research worldwide for their regenerative abilities. Researchers predict there is a way to reverse Stemotl's morphing process; however the process is still being studied.

Neurotl (Chroma/Neura): The covers on Neurotl's body are smaller when the Neurotl is unwell, causing them to have slower movement. Neurotls can communicate with others through the electrical shocks they send out of their tail.

Myotl (Chroma/Forta): Fully relaxed Myotl arms can stretch out to be pretty long; however some parts are usually contracted. Myotls can understand the secret messages Neurotls communicate through the Neurotls' tails.

Dermotl (Chroma/Phasma): Dermotl's wings are grown from Dermotl's body and they have to be replenished as parts of the wing shed off over time. Dermotls sometimes rip-off their cloaks to protect younger Stemotls.

Osteotl (Chroma/Metalla): Osteotls can make a sturdy home for themselves by spitting out and forming a bone matrix which they can reabsorb if needed. Some reports claim seeing a Myotl throw an Osteotl at an enemy to deter them with Osteotl's spines.

Adipotl (Chroma/Toxa): The sticky covers on Adipotl allow them to stick to each other and various surfaces to block certain passageways. Adipotls can use their storage to generate heat in cold climates, welcoming Stemotls to huddle around them.

[moonstruckmutt]

Fat Cell diagram for a college science class in 2022, rehearse for your science quiz here

[belliesandburps]

This is a looooong overdue poll winner from Twixxer of a Hawks pose. Since I've been pretty into the Hawks x Dabi ship lately, I decided to get a bit indulgent, making Hawks especially bloated so Dabi can give that big, sloshy belly a good jostlin'...aaaaaand maybe work up a monstrous burp or two from the greedy bird brain. :P

[fangirltothefullest]

Went to a new doctor today. She's skinny. Of course she saw me and diagnosed me fat immediately. Mentioned cholesterol and diabetes and thyroid issues three times and ordered same day blood work. And on top of that she looked into my mouth and just decided to tell me that I should look into seeing a dentist. Like EXCUSE me??? You are not q dentist you have no right to shame me when my teeth are fine??? I don't understand why she felt the need to make me self conscious over something she has ABSOLUTELY NO EXPERTISE IN.

This is why I hate doctors but ESPECIALLY skinny doctors. They don't give two shits about you, they don't care how healthy you are they see weight that isn't stick figure, diagnose you with fat and won't hear any other problems you might have without telling you to lose weight first which is BULLSHIT and all the studies now are saying we have been thinking about weight wrong and the healthiness of your body is not weight-controlled.

Anyways I'm switching to a heavier doctor that my sister has whose nice and actually cares, but I spent an already anxiety-filled time at the doctor masking my fucking heart out and getting my blood drawn and having to on top of that come out feeling ugly and like I don't take care of myself.

To any of you who might be getting your doctor degrees or whatever, stop fucking treating fat people like we don't have feelings. Stop treating us like we are ugly horrible people. And for fucks sake mind your fucking business when it comes to information you know Jack Shit about. Stay in your own goddamned lane.

[bluehairlaunch]

Top 7 Dragon Ball characters that never met (but should have)

Honorable mention, Lord Frieza and Goku Black. Goku Black has the face of the man Frieza despises most, while Frieza's subjugation and genocide of the galaxy is exactly what Zamasu fears and abhors about mortals. They're basically each other's respective boogeymen.

Launch & Vegeta

Like she'd shoot his ass, right? And then sneeze and suddenly Vegeta thinks all humans can do that.

Gohan & King Piccolo

Lil' G got a small taste of what a bastard Piccolo used to be in the Saiyan Saga, but that paled in comparison to the genocidal freak that was the Demon King. I don't think it would be hard for them to meet either, because Piccolo is both the King and himself. Him regressing or being controlled somehow by his father would make for great stakes as well, way better than just bringing Cell back like a bunch of fucking hacks.

Baby & Frieza

Basically the opposite of Zamasu and Frieza, these two would be natural allies if they could keep their smugness (and smirks) under control. Sure, they'd both be fitting the other for a dagger in the back from almost the moment they met, but they're gonna fail to kill Goku anyway, it's in their nature, so in the end it would never come to that. And then they'd be besties in Hell

King Cold & Goku

C'mon, this is interesting. If some twink hadn't shown up to ruin their fun, we could've gotten the generic shonen rematch, followed by King Cold going whatever the Frieza-race equivalent of Super Saiyan is when Goku inevitably wastes his baby boy again. I'm glad twinks with lavender hair exist, but this wouldn't have been the worst timeline, would it?

Good Buu & King Kai

Finally, someone who would laugh at King Kai's jokes. Korin and Puar were th|i|s close to snagging this slot btw. Because they're both cats you see

Dr. Gero & Cell

The good Doctor Frankenstein has never even met his Frankenstein's Monster in any timeline. Would he be pleased? Cell definitely wouldn't obey him and would only incidentally kill Goku. Would Cell be thankful? Is Gero willing to sacrifice all of humanity for his revenge? Fanfiction writers, please

Gohan & the Great Saiyaman

[opens-up-4-nobody]

Cyanobacteria my beloved 🖤

[bpod-bpod]

Vessels and Bones

Did you know that the menopause increases a woman’s risk of developing osteoporosis? Usually the hormone oestrogen protects female bones and crucially the blood vessels within them. At menopause, those hormone levels drop dramatically, accelerating bone loss and fragility. The fat cells surrounding blood vessels also cease to be broken down, no longer efficiently fuelling vessel growth. Researchers revealed that low oestrogen levels in postmenopausal mice created a build-up of a toxic substance called lipase peroxide. This impedes their ability to form the vital blood vessels which support bone formation. But they were able to repair some of this damage using a drug called Liproxstatin (right) which broke down the fat cells (green) and increased the blood vessels inside the bone (red) compared to mice with low oestrogen levels (left). Targeting the build-up of lipase peroxide is a promising alternative to oestrogen hormone replacement therapy which has its own side effects.

Read more about this research from the MRC LMS here

Written by Sophie Arthur

Image from work by Julia Rodrigues and colleagues

MRC London Institute of Medical Sciences, Imperial College London, London, UK

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in Nature Cardiovascular Research, October 2022

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[ineffable-idiot-666]

Whoop

bisexual boy

I had fun shading his FOREHEAD HAHAHA BIG L

I dunno where I'm going with this

anyway, on another note, I'm working on Chekov rn and I think I will probably be finished with him in the next 2 days.

:) <3

[biracy]

Anotherrrr Ianthe study bc I didn't like my first one and her face is hard. Can we not make pussy cunt cunt jokes about a literal murderer

[interestinglittlerelationship]

[sportsandlaughs]