#white matter

[bpod-bpod]

Reining-in Flaviviruses

Flaviviruses have existed for thousands of years and still hit the headlines, most recently with Zika virus. They can fatally infect the human brain. Your body defends against them by making the protein interferon type I (IFN-I). How IFN-I affects the ability of flaviviruses to infect different cells (tropism), which determines the infection's spread, isn't clear. Researchers investigate by infecting the brains of normal mice and mice genetically altered so they're unresponsive to IFN-I, with the flavivirus, Langat virus. Combining optical projection tomography (OPT) with MRI revealed virus distribution in the brain (pictured). In normal mice (two views left), the virus only infected grey matter in sensory brain areas. In mutants (right), it spread further, infecting white matter. The team revealed the spread into white matter-targeted cells called microglia. Normal mice brains had more IFN-I activity, which protected microglia, uncovering IFN-I's role in viral tropism.

Written by Lux Fatimathas

Image from work by Nunya Chotiwan, Ebba Rosendal and Stefanie M. A. Willekens, and colleagues

Department of Clinical Microbiology, Umeå University, Umeå, Sweden

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in Nature Communications, April 2023

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[economicsresearch]

page 180 - my dream job, a roller skating server at a retro diner celebrating an america that has been lost or possibly never was. I was fired because I kept asking people what it was like to be trapped inside a collective national dream.

Also, missed a bunch of shifts, dropped hot fries and cold shakes on a congressman, etc.

That right there is a nice looking cake though. DAMN I love frosting.

[catmask]

does anyone have like an anti aesthetic. like something you look at and can recognize as a complete fashion/interior design/artistic movement and understand it but it makes you shudder seeing it. i am not talking like “its morally bad” “its poorly structured” like just sheerly devoid of joy for you actually invites a repulse response.

[padawan-historian]

If you can't show up in person, make a phone call. If you can't call, write a letter. If you can't write a letter, an email.

In order to liberate our communities from this lovecraft country's Jim & Jane Crow violence, we have to upRoot white supremacist politics and practices from the root.

[svampira]

snack time🤤

[estefanyailen]

[riviclouds]

*pets him with a slightly damp toothbrush*

[torvagatai]

Firstprince + textposts

[repmet]

Firstprince + hugs

[poorly-drawn-mdzs]

Alas, this beautiful dream could not last.

[economicsresearch]

page 180 - is that a fish? Are those fishes?

I can hear a sound that can only be described as flopping about, but I can’t see anything.

Maybe there’s an underground river that is finally re-emerging, soon to fill the cell and drown all the creatures that live herein.

How many creatures live here, and do I count my surviving gut biome individually?

What does a bat taste like?

[foureverbrave]

Red, White, & Royal Blue + Heartstopper title cards

[padawan-historian]

Black solidarity with Palestine against apartheid tomorrow and forever!

[nibbelraz]

What if his hair just goes between black and white throughout the year

[hussyknee]

Motaz posted ''follow Shaun King" in his IG story today. It's not his fault, or even his concern at this point, but Shaun King is a notorious misogynoiristic grifter that Black women have been trying to warn us about for years and one of the people who have also been exploiting the pro-Palestinian movement. Motaz has taken the story down, probably having been informed, but it just means that we have to be more careful ourselves and make it known to as many people as possible who to avoid. Palestine deserves more than the scum of the earth exploiting its suffering to inflict the same on other marginalized and innocent people.

[dumblr]