lizzpgara-blog

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Bijuu's 🍥

Gaara: Shukaku aka Ichibi; Yugito Ni'i de Kumogakure: Nibi; Antiguo Mizukage: Sanbi; Roushi el estilo de lava: Yonbi; Han de Iwagakure: Gobi; el Ninja renegado se Utakata: Rokubi; Fuu de Takigakure: Nanabi; Killer Bee: Hachibi; Naruto: Kyuubi

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NARUTO

Bijuu de Gaara: Shukaku aka Ichibi@Bijuu de Yugito Ni'i de Kumogakure: Nibi@Bijuu del antiguo Mizukage: Sanbi@Bijuu de Roushi el estilo de lava: Yonbi@Bijuu de Han de Iwagakure: Gobi@Bijuu del ninja renegado se Utakata: Rokubi@Bijju de Fuu de Takigakure: Nanabi@Bijuu de Killer Bee: Hachibi@Bijuu de Naruto (el espíritu del zorro de Konoha): Kyuubi

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More information: Tomoaki M. Kato et al, Ant1 mutant mice bridge the mitochondrial and serotonergic dysfunctions in bipolar disorder, Molecular Psychiatry (2018). DOI: 10.1038/s41380-018-0074-9

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6 Signs You May Have Anxiety and Not Even Know It

Anxiety isn’t fun for anyone. We all know what it’s like to feel our stomach do flips or to panic over things that we feel we have no control over. Some of us soak our clothes with sweat before a job interview or a presentation. Others have trouble gathering their thoughts and forming words, leaving them tongue-tied. More often than not, we notice these physical reactions to our stress. That poor sweaty interviewee usually takes a trip to the bathroom, dabs themselves with some paper towel, and takes a few breaths. The stuttering speaker may slow their speech down to make talking easier. But are we always so in-tune with our mental states? There may be some signs of anxiety that you’ve been ignoring. Here are 6 signs that you might have anxiety, and not even know it.

1. Chronic Headaches

Are you prone to migraines, or long-lasting headaches? Have no fear, there are lots of others like you. If you have throbbing head pain that won’t stop coming back no matter what you do to treat it, you may….

Continue Reading Here

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When scientists get too honest

> I would love to see more science posts on Tumblr. I particularly liked, “The postdoc who did all the work has since left to start a bakery.”

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Pneumonia

 “Pneumonia is called the old man’s friend because, left untreated, the sufferer often lapses into a state of reduced consciousness, slipping peacefully away in their sleep, giving a dignified end to a period of often considerable suffering.” -Dr John Pillinger

Pneumonia is a major cause of morbidity and mortality worldwide, the 6th largest cause of death in the USA. It is also economically costly in antibiotics, time off work, and hospitalisation

In half the cases the cause is not identified

In those where a cause is identified, S. pneumoniae is the most common cause

The reservoir is usually humans (oneself or a contact) 

spread is through respiratory droplets

Community acquired eg Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, Chlamydia pneumoniae

Noscomial (hospital acquired) eg Enterobacteriaceae, Staphylococcus aureus, Anaerobes, Pseudomonas aeruginosa

Many patients have an underlying condition, e.g. bronchitis, asthma, a viral infection, tumours

Characterised by the alveolar sacs filling up with pus, giving rise to a purulent sputum

Symptoms

Results in chest tightness or pain, difficulty in breathing, fever or hypothermia, reduced blood oxygen, coughing to clear mucus, chest will sound “dull” when tapped, tachypnea, tachycardia (>100 bpm) or bradycardia (< 60 bpm), central cyanosis, altered mental status.

Streptococcus pneumoniae: Rust-colored sputum

Pseudomonas, Haemophilus, and pneumococcal species: May produce green sputum

Klebsiella species pneumonia: Red currant-jelly sputum

Anaerobic infections: Often produce foul-smelling or bad-tasting sputum

Diagnosis

X-ray showing infiltrates

Elevated temperature

Changes in WBC counts

Culture confirmation

Serum chemistry panel

Arterial/venous blood gas 

Serum free cortisol value and lactate level

Treatment

Intensive treatment, potentially to ITU level

Tailored antimicrobials if possible - limited options with viruses

Treatments include: analgesia and antipyretics, physiotherapy,  bronchodilators and N-acetylcysteine, suctioning and bronchial hygiene, ventilation 

Pathogenesis 

Causative agents can enter the lungs through inhalation, aspiration, spread across mucous membrane (some viruses), haematogenous spread (occasionally, e.g. IV drug users with S. aureus septicaemia) and penetrating injury (rare).

Immune response is triggered in the lung and there are local defence factors in the respiratory secretions

Cilia, if functioning, will move material up the respiratory tract, but if damaged this physical defence is impaired

The lungs also have a resident macrophage population (alveolar macrophages) but they are of limited use against several respiratory pathogens that possess a capsule

some organisms can even replicate in these cells

Damage to the lung is caused by the microbes and the immune response

 Enzymes released by the bacteria

Factors released by immune cells that cause local irritation and cell apoptosis

Systemic manifestations follow eg

Oxygen deprivation – thickening of the membranes reduces gas transfer

Systemic shock – especially with Gram-negative bacilli such as Haemophilus influenzae

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If you’re an introvert, follow us @introvertunites​

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The more you love your own decisions the less you need others to love them.

(via psych2go)

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Current Great Houses vs Extinct Houses

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NaruHina + Ichiraku Ramen ♥ BONUS:

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The Comically Serious: After his Heel-Face Turn, he frequently acts as a straight man foil to Guy and Lee’s insane enthusiasm, however sometimes Neji proves to be Not So Above It All, leaving Tenten as the Only Sane Woman.

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Scars have the strange power to remind us that our past is real.

Cormac McCarthy (via psych2go)

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JOIN THE INTROVERT NATION MOVEMENT

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{ ナルト }

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Follow @justsimpledk

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If you’re an introvert, follow us @introvertunites. 

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JOIN THE INTROVERT NATION MOVEMENT