philsom-blog

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Results of the brainstorm session given by Allard. The outcomes of possible harmfull outbrakes are particularly funny!

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The idea of my prototype I tried to explain with text earlier.

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The wireless connection I want to try to fake by using this colour sensor connected to a RF12-chip. this chip sends the information wireless to a computer or Ipad. The RF12-chip and colour sensor are in a device you can hold in your hands. Then it sends a simple signal to the computer/Ipad. Every different colour gives a different signal. Every different signal has an interface of their own on the device. On the device you could then ‘alter’ the organism you scanned with the sensor. 

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The collection. NOTE: I think I should skip the USB parts, it is way more futuristic if the information would go from one device to the other wireless. 

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Other tools that are present in the BioLab

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A tool that reads the DNA thats inside a tube (the tube is inserted in the device, on the left here). The DNA letters can be altered on the screen (middle), and then can be put in your computer with the usb output (on the right).

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Injection needle equiped with several tubes that you could take out- and in, if you want to use them you put them inside the seringe. Then you can inject the CRISPR components.

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The first tool I made, a sampling device (sampling will occur by pressing the button, then the knifes at the bottom will cut a piece of). It is equiped with DNA-reader and a usb output.

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My first graphic interface of a simplified Genetic modification tool.

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This is a site where you can order your pre programmed CRISPR components. Just look how frikking frictionous it looks with the name and scissor.

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There are still questions about how precise exactly crispr is, what might the side effects be? THere is a chance of off-target-effects, you could think you are editting one thing, maybe the crispr component editted something else too. Or the gene we thought just does this ONE thing does something really important that we didn’t know. In America, if crispr editting leads to organisms that could not have been created the same by long-term breeding, they are viewed as new drugs and have to go through a huge testing phase.

As a new animal pharmacetuical drug Brazil and argentina have a very “relaxed” regulatory standpoint on gene editing Our immune systems may reject CAS9 if they dealt with a bacteria that also carries this protein, so in that case crispr wouldnt work at all.

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We still only know what 1-2 % of our DNA does! So this increases te chance of off-target effects from genetic engineering A LOT.

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Humans could be immune to CAS9?! Making CRISPR impossible?! No, we will find other ways to use this technology and surpass this prolbem.

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Zayner explaining how CRISPR that is accesible tot he common folks in our population could drastically speed up our CRISPR knowledge and applications.

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Nice talks about CRISPR, ethics, possibilities, etc… It is stated that for now it is still pretty hard to determine simple human fenotype Genomics hence hard to determine how to alter them. It quite a bit outdated (2 years old video, but for such a new development as CRISPR that’s already quite outdated. CRISPR CAS9 was first experimented with in 2015.). They also talk about how other proteins then CAS9 that may work but still need tob e found (now we know there is also CAS3 and CAS11 I believe) and they talk about totally different proteins or other things we don;t think of now, that could sync with CRISPR.