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Osteoarthritis, Pain Control, and Anti-Inflammatory Drugs
Affecting more than 27 million people in America, Osteoarthritis can affect any joint in the body, but usually affects the small joints in the fingers, the big toe, and the bases of the thumb, hips, knees, lower back and neck.
It is also known as degenerative arthritis or degenerative joint disease, and is basically caused by the wear and tear or rather breakdown of the joint cartilage or Hyaline cartilage that is found on the joint surfaces. The cartilage has a lot of collagen and its function is to provide a lubricated surface that allows the reduction of friction and the smooth movement of the joints. Unfortunately, the cartilage has a limited capacity for healing and repair, and any breakdown in it could result in a chronic condition known as Osteoarthritis. When the cartilage breaks down, it could lead to pain, swelling and stiffness in the joints that impairs free movement.
The symptoms of Osteoarthritis are usually pain following an activity or during it, stiffness of joints, cracking or clicking sound when the joints make a bending movement and mild swelling. Simple daily life activities that one takes for granted like walking, climbing stairs, holding a car steering wheel, opening a box, lifting things, etc., becomes difficult depending on where and how Osteoarthritis affects the body.
Common in both the sexes, before the age of 45 for men and after the age of 45 for women, the most visible sign of this joint disease is the enlargement of bones particularly the formation of hard knobs at the joint of the middle finger (Bouchard’s nodes), hard or bony swellings at the joints closest to the ends of the fingers (Heberden’s nodes), and an unnatural bony hump at the base of the toe (Bunions).
X-rays help detect Osteoarthritis as they show loss of joint cartilage, narrowing of the joints space between adjacent bones and bone spur formation. Arthrocentesis is performed by the Doctor in his office with the help of a sterile needle to remove the joint fluid for further analysis to help determine the proper diagnosis and the type of arthritis. Arthroscopy is done by inserting a viewing tube to detect abnormalities and any damage to the ligaments and cartilage through the arthroscope. Analysis of many factors can help the doctor in diagnosing Osteoarthritis and its appropriate treatment.
Since this disease is degenerative, there is no cure; however, the symptoms can be treated. Also, lifestyle changes like exercising, diet, maintaining a healthy weight, and medication to relieve pain are some of the ways in which this condition can be treated. Also, applying ice packs for 20 minutes can relieve swelling and pain.
Nonsteroidal anti-inflammatory drugs can give pain relief, but you must take them only as per strict instructions from your doctor as these drugs may cause side effects. Gels or cream rubs do help relieve joint pain and swelling considerably, but should be used only on the advice of a doctor.
Hyaluronic acid injections may be prescribed by your doctor to lubricate your joints and keep them moving smoothly. Hyaluronic acid is just like the natural fluid that the body produces to keep your joints free from stress when you walk. It is only prescribed if the patient does not seem to favorably respond to other conventional treatments. Joint replacement surgery (arthroplasty) is done after thorough consideration by the surgeon if there is a need to remove damaged joint surfaces and replace them with artificial ones.
It is very important for a person not to get overwhelmed by Osteoarthritis and to handle it positively so that the body can help itself with the natural healing process.
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What is Osteoarthritis?
Do you feel off and on again pain in your fingers or knees? It could be Osteoarthritis, which is a degenerative joint disease. Osteoarthritis is the most common chronic condition of the joints, affecting approximately 27 million Americans according to the Arthritis Foundation. It can affect any joint, but it occurs most often in knees, hips, lower back and neck. It is characterized by the degeneration of the articular cartilage, specifically in the fingers, knees, hips, feet and spine and has been known to lead to inflammation, limitations in movement, severe to debilitating levels of pain and eventually joint destruction to the point of bone rubbing on bone.
This disease, affects mostly, but not limited to, elderly Americans and has no known cure. Currently all methods of treatment are only symptomatic. Generally, treatment of Osteoarthritis treats the pain of the affected area, either through non-steroidal injections or pain and health supplements.
Despite the medical community having no current means of regeneration of the loss of joint tissue caused by Osteoarthritis, several methods exist to manage the progressive loss of tissue in its early stages, and surgery for more advanced stages. However, as with any surgical procedure there are always chances of potential complications including, but not limited to, Thrombosis, infection, as well as high cost in hospitalization and rehabilitation, and an increased risks of Osteoarthritis after meniscus or an anterior cruciate ligament injury.
Three main methods of managing Osteoarthritis, known as The Three Generations of Biologic Injections, have been developed to better manage the levels of pain caused by the disease:
The First Generation:
Focused on the early stages of the onset of Osteoarthritis, this injection is known as Hyaluronic Acid. Generally only having a temporary effect at the injection site, this type of injection has been shown to work for knee pain.
The Second Generation:
Known as a Platelet-Rich Plasma (PRP) Injection, this form of injection has been shown to be more effective than a Hyaluronic Acid Injection due to the injection being “prepared from one to a few tubes of the patient’s own blood with strict aseptic technique,” reducing chance of rejection from the body.
The Third Generation:
Finally, with the growing field of stem cell research, a stem cell treatment using a form of stem cell known as the Adult Mesenchymal Stem Cells has developed. MSC’s, which have been found to attach to sites with inflammation and injury, and have a reduced count in patients with severe osteoarthritis, “have shown potent anti-inflammatory and immunosuppressive activities,” and similar to PRP Injections, due to the source material of the injection being made from the patient’s own body, lower rejection rate and higher effectiveness against pain and inflammation occurs.
At The Stem Cell Orthopedic Institute of Texas, at the Medical Center in San Antonio, is dedicated helping patients who suffer from any type of joint pain. Our motto is, “the pain stops here.” Learn more about Osteoarthritis by visiting http://spinaldoc.com/resources/signs-symptoms-lower-back-pain/.
If you are suffering from any form of arthritis or joint pain, please call us to setup an appointment at (210) 293-3136.
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Learn What are Stem Cells – Stem Cell Orthopedic Institute of Texas
Stem cells are unspecialized cells. They will divide to produce more stem cells but do not take on a specialized task. THE STEM CELL ORTHOPEDIC INSTITUTE OF TEXAS provides the most effective STEM CELL treatment.
http://stemcellorthopedicinstituteoftexas.com/
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Learn what are Stem Cells and What Does Stem Cell Therapy Do
What are Stem Cells?
Our bodies are composed of billions of different, specialized cells. Each one has its own role to fill in our organs, tendons, joints, muscles, etc. Stem cells are unspecialized. They will divide to produce more stem cells but do not take on a specialized task. Under certain conditions, however, stem cells can be induced into becoming a tissue-specific, specialized cell.
Somatic stem cells, or adult stem cells, are unspecialized cells that are found throughout the body, inside tissue and organs. These cells exist to produce more cells. They aid your body by regenerating damaged tissue and replenishing dying cells.
What is Stem Cell Therapy?
Stem cell therapy is a non-surgical option for repairing internal damage by replenishing or replacing old tissue. A patient has a sample of their adult stem cells extracted, cleansed in a laboratory, and then injected back into the impacted area of their body. The injection process usually takes less than one hour.
As the stem cells come from your body, there is no risk of rejection. They have always belonged in your body so your immune system does not take issue with them, despite their new placement.
How do stem cells help with my arthritis pain?
When tissues are worn down over time or suddenly traumatized, your natural configuration of stem cells isn’t enough to match the breakdown of injured tissue. The regeneration process is slower than the degenerative process. An ineffectual recovery may result in weaker internal structures, decreased function or chronic pain.
Injecting stem cells into the impacted area advances your body’s natural healing process by greatly increasing the regenerative abilities that specific location. Depending on your condition, improvement appears between 2 to 4 weeks.
What conditions can Stem Cell Therapy treat?
Stem cell therapy can aid with:
1. Osteoarthritis
2. Hip Pain
3. Knee Pain
4. Degenerative Disc Disease
5. Rotator Cuff Tear/Tendinosis
Is there a long recovery time?
Unlike surgical options, stem cell therapy has minimal recovery time. It is an outpatient procedure and most patients walk out of the clinic without assistance. Low impact activities are encouraged immediately after the treatment. In 4 to 6 weeks, full impact activities are allowed.
Still not sure about stem cell therapy? Listen to our Patient Stories and see how treatment improved the lives of our patients.
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Treating Pain with ADULT STEM CELL THERAPY - The STEM CELL ORTHOPEDIC INSTITUTE of Texas
vimeo
Dr. David Hirsch D.O. of The STEM CELL ORTHOPEDIC INSTITUTE of Texas presents an overview STEM CELL therapy.
The STEM CELL ORTHOPEDIC INSTITUTE of Texas – use ultrasound and fluoroscopy guided, minimally invasive treatments of ADULT STEM CELLS harvested from Bone Marrow.
http://stemcellorthopedicinstituteoftexas.com/
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Stem Cell and Stem Cell Therapy - THE STEM CELL ORTHOPEDIC INSTITUTE OF TEXAS
What are Stem Cells?
Our bodies are composed of billions of different, specialized cells. Each one has its own role to fill in our organs, tendons, joints, muscles, etc. Stem cells are unspecialized. They will divide to produce more stem cells but do not take on a specialized task. Under certain conditions, however, stem cells can be induced into becoming a tissue-specific, specialized cell.
Somatic stem cells, or adult stem cells, are unspecialized cells that are found throughout the body, inside tissue and organs. These cells exist to produce more cells. They aid your body by regenerating damaged tissue and replenishing dying cells.
What is Stem Cell Therapy?
Stem cell therapy is a non-surgical option for repairing internal damage by replenishing or replacing old tissue. A patient has a sample of their adult stem cells extracted, cleansed in a laboratory, and then injected back into the impacted area of their body. The injection process usually takes less than one hour.
As the stem cells come from your body, there is no risk of rejection. They have always belonged in your body so your immune system does not take issue with them, despite their new placement.
How do stem cells help with my arthritis pain?
When tissues are worn down over time or suddenly traumatized, your natural configuration of stem cells isn’t enough to match the breakdown of injured tissue. The regeneration process is slower than the degenerative process. An ineffectual recovery may result in weaker internal structures, decreased function or chronic pain.
Injecting stem cells into the impacted area advances your body’s natural healing process by greatly increasing the regenerative abilities that specific location. Depending on your condition, improvement appears between 2 to 4 weeks.
What conditions can Stem Cell Therapy treat?
Stem cell therapy can aid with:
1. Osteoarthritis
2. Hip Pain
3. Knee Pain
4. Degenerative Disc Disease
5. Rotator Cuff Tear/Tendinosis
Is there a long recovery time?
Unlike surgical options, stem cell therapy has minimal recovery time. It is an outpatient procedure and most patients walk out of the clinic without assistance. Low impact activities are encouraged immediately after the treatment. In 4 to 6 weeks, full impact activities are allowed.
Still not sure about stem cell therapy? Listen to our Patient Stories and see how treatment improved the lives of our patients.
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The STEM CELL ORTHOPEDIC INSTITUTE of Texas present an overview of ADULT STEM CELL THERAPY from sedation, extraction of bone marrow rich in MESENCHYMAL STEM CELLS, spinning out of buffy coat and ultrasound-guided injection.
Learn more about Adult Stem Cell Therapy: http://stemcellorthopedicinstituteoftexas.com/adult-stem-cell-therapy/
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Learn What is Osteoarthritis and Osteoarthritis Treatment – Stem Cell
What is Osteoarthritis?
· Osteoarthritis is the most common type of osteoarthritis characterized by degeneration of the articular cartilage and ultimately joint destruction. It is estimated that 27 million Americans 25 years of age and older have clinical osteoarthritis of some joint, with a higher percentage of affliction in the older population.
· Human aging is associated with bone and joint degenerative changes that include loss of bone density and ligament flexibility. Chronic musculoskeletal pain accounts for the most medical complaints in the United States with nearly 15 million Americans reporting dysfunction in activities of daily living (ADL’s) as a result of a musculoskeletal ailment.
· Osteoarthritis is a progressively debilitating and irreversible disease that affects mostly cartilage and associated changes in the bone and synovium. Once considered only in the elderly, osteoarthritis is seen in younger patients, affecting all joints such as the hands, knees, hips and the spine being the major problematic sites.
· Generally, cartilage defects in Osteoarthritis are usually large, unconfined and affect more than one location.
· Acute cartilage injury often occurs in normal young patients and probably requires localized treatment in contrast to patients with Osteoarthritis in the elderly where the entire joint surface will require treatment. This cartilage damage eventually leads to decreased function and loss of mobility and autonomy for the patient
· Osteoarthritis is a complex condition with broad pathology with clear links to other conditions such as neuropathic pain, depression, and sleep disorder, and is often characterized as a biomechanical disease associated with abnormal joint loading from obesity, joint instability, or trauma, and inflammation of the joints, and genetics.
· There is a poor understanding in the disease mechanism of Osteoarthritis associated with:
o A lack of biomarkers of early disease.
o Slow progression.
o Signaling pathways, biomechanical events and cellular functions remain obscure.
· Manifestations of Osteoarthritis include:
o Joint pain.
o Impairment to movement.
o Local tissue inflammation surrounding the joint.
· Much of the Osteoarthritis research today has focused on the loss of articular cartilage by:
o Insufficient repair response
o Mechanical stresses.
o Aging or dead cells that cannot produce cartilage.
Synovial Changes
· The synovium plays a crucial role in the development of Osteoarthritis of the joint. Synovial inflammation occurs in the majority of patients and is a predictive factor in the disease progression.
· Infiltration of T cells and macrophages are increased in the synovium in early Osteoarthritis. This indicates synovial inflammation is a feature in early disease and might be an indicator of future tissue destruction.
· The synovium seems to have two faces to its role in Osteoarthritis
o Inflammatory
o It may be the focus of effective repair responses involving local populations of mesenchymal stem cells (called MSC’s), where the MSC’s become activated and are capable of differentiating into cartilage, bone and other tissue which might provide repair cells to help to maintain healthy joints.
Current Treatment in Osteoarthritis
· It is a striking fact that no appropriate pharmacological intervention, biological therapy or procedure prevents the progressive destruction of the osteoarthritic joint. All current treatment regimens produce symptomatic rather than regenerative results, for example:
o Non-steroidals for pain.
o Viscosupplementation with injection of sodium hyaluron (Synvisc)
o Nutraceuticals like chondroitin sulfate, omega 3- fatty acids, etc
· Non-pharmacological and pharmacologic treatments are used for early and moderately early cases of Osteoarthritis, but protection of the articular cartilage has not been shown.
· None of these treatments have a useful impact on the progressive loss of joint tissues that leads to the total joint replacement.
· Total joint replacement can be successful resulting in enhanced mobility and reduction in pain, but surgical procedures come with associated risks, which include:
o Thrombosis, infection and a very high cost in hospitalization and rehabilitation.
o There is also an increased risks of Osteoarthritis after meniscus or ACL injury.
Source: http://stemcellorthopedicinstituteoftexas.com/oste oarthritis/
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