#RBC Convention Center
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savantefolle · 2 years ago
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Get a taste of my fiction at the Pemmi-Con !
the 15th North American Science Fiction Convention opens today at the RBC Convention Center at Winnipeg, 20-23 July 2023. Meet me at the dealer's room with my indie publishing house Echofictions.
The Pemmi-Con, the 15th North American Science Fiction Convention opens today at the RBC Convention Center at Winnipeg, 20-23 July 2023. Meet me at the dealer’s room with my indie publishing house Echofictions. Short and sweet chocolate SF stories for the busybodies! (Echofictions’ corner table at the back of the Dealer’s room) “Echofictions provides short and sweet books for readers living…
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bentuckett1997 · 3 months ago
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Happy 50th to #Winnipeg #RBC Convention Center (1975-2025)!
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aryburn-trains · 2 years ago
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Only a few months old at the time, shiny GO Transit F40PH 511 heads up a westbound 9-car train of new bilevels and an APCU on the tail end, passing by Spadina Avenue just west of Toronto's Union Station. GO 511 was part of a six-unit order of F40PH units built by GMD at their London ON plant in April-May 1978, a change from GO's previous orders of freight GP40-2W units. New F59PH deliveries a decade later would result in GO flipping the six orphan units to Amtrak in 1990. 511 would see another decade of service on Amtrak as their 411, and would go on to work AMT's commuter operations out of Montreal. It last saw service on the the Saratoga & North Creek Railway (via LTEX) with another ex-Amtrak F40. The bilevel cars trailing are also new, part of the first order built by Hawker Siddeley and in service for a little over a year since introduction in March 1977. Since the first bilevel order included no cab cars, another locomotive, APCU, or old Hawker Siddeley single-level cab car had to be used on the other end in the early years. This scene off Spadina Avenue is notable in that it's under transition: the old CN steam-era freight platforms, team tracks and yard trackage east of Bathurst Street yard are still present, but truncated for the new CN Tower's parking lot (note the yellow bridge crossing the rail corridor near TTR's John St. interlocking tower). In later years the RBC's new data center (325 Front St. W), the Metro Toronto Convention Centre and CN's L'Hotel would fill much of the vacant land along Front Street in the 80's. The usual downtown office towers of the day including the TD Centre, Royal Bank Plaza, CP Hotel's Royal York, and the CNCP Telecommunications Building (151 Front Street) are quite unobscured compared to today. July 30, 1978 Bill Mischler photo
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buzzybuttons · 8 years ago
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THAT IS RIGHT! We are going to the Manitoba Comic Con Expo this April 1st and 2nd at the RBC Comic Con! Our table is shared with the talented @kurewkreations and @pcaskey So look for there big ass backdrop! 
We have new art and new buttons, as well as a new display! So come and join us. 
we also have a really unique thing this time. That is right the capsule machine will be there and we even have a special button that will let you win a prize (prize to be announced at the convention) So come and try your luck. 
Capsules are $2.00 each and contain three buttons of various designs. 
Otherwise buttons will be $3.00 each or 5 for $10.00!!
Can’t wait to see you all there!
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austabeclair-blog1 · 6 years ago
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Techniques for Condo Vs House Calculator Only the Pros Know About
The Advantages of Condo Vs House Calculator
Learn which option is right for you, buying a home or renting a house. A house that's too expensive cannot be eligible for an FHA loan. It affords owners a lot of freedom and independence when it comes to implementing their own ideas about design and style. When the majority of people talk about purchasing a house they mean buying a single-family house, which is a stand-alone structure on a foundation. Finally, here are a few reasons you may want to avoid buying a home. For some people, it is simply part of their American dream. Most houses can be found far from business centers, which can impact the simplicity of access to significant hubs.
The Upside to Condo Vs House Calculator
Mortgage rates have a tendency to follow the exact same path as long-term bonds. The best-fixed rate of Conventional mortgages may provide a reduced rate of interest and APR than other kinds of fixed-rate loans. A house equity loan rate is the rate of interest you pay on a house equity loan.
FHA loans are a good choice for first-time homebuyers who might not have saved enough for a large down payment. Lenders may charge a lower rate of an interest rate for the initial length of the loan. Lenders give you a greater interest rate when financing a condo when compared with a home. Many lenders provide a house construction loan that covers construction expenses. There are several different kinds of mortgages that homeowners can choose which will have varying rates of interest and monthly payments. Locate a neighborhood lender in minutes who can assist with your mortgage pre-approval. The 15-year fixed-rate mortgage enables the borrower to pay back the mortgage faster and typically has a very low rate of interest.
Visit- www.theavenuesouthresidences.com
Whether you pick a condominium or a free-standing home, mortgage prices are low.  Condominiums are an excellent pick for busy professionals or retirees, who are interested in being in an excellent place but don't want to pay the greater price for a single-family property. Or, employ a real estate attorney who's knowledgeable in condominiums to examine the documentation and provide you an outline of the significant points. Condominiums have a tendency to be less costly than single-family houses in the exact same location.
New Step by Step Roadmap for Condo Vs House Calculator
Condos have quick-selling capabilities. Condos also demand certain accommodations in regards to everyday life, too. They are often considered easy, low-maintenance options to park your money, banking on the idea that the condo will appreciate over the years and you will someday be able to sell it for a substantial gain. They are usually more affordable than a house, even with the housing market in flux. Purchasing a condo vs. renting is a challenging decision in much of the nation. Whether you're purchasing a condo or a home, the property ought to be thoroughly inspected as a contingency of purchase. After coming to terms with the loads of money you are going to be borrowing, you will have to decide on whether you need to reside in a condo vs house.
If you purchase a condo, you will have the interior space of your unit and in certain circumstances a parking space. Of all Of the home types on the sector, condos require the smallest amount of maintenance. Condo vs. House RBC Royal Bank Condos has a tendency to be more affordable than single-family houses in the exact same place.
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newstattoos · 2 years ago
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ST. JAMES-ASSINIBOIA Winnipeg Tattoo Show returns after a 2-year break, from May 12-14 at the RBC convention center. J&A Inked Enterprises present the fourth annual convention, but the co-founder says friends and volunteers almost entirely put it together. “We just do it for the love of the industry,” said Abigail Boivin, 40, who came up wit...
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floorcountrycanada · 3 years ago
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Come visit us at the 2022 Winnipeg Home and Garden Show at the RBC Convention Center booth 413. Our friendly staff will be there to answer all your questions and to help you with all your flooring needs. There are lots of show specials featuting all the top brands for you to see. Come out and let us floor you this weekend. (at RBC Convention Centre Winnipeg) https://www.instagram.com/p/CcIhZOtrzx0/?igshid=NGJjMDIxMWI=
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1litrewater · 4 years ago
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Women of DeFi: How Maggie Love Makes DeFi More Relatable with SheFi
There are many crypto talking heads to look over, and unlimited things to learn. Anybody in the space thinks about the substance over-burden, stun, and weariness from learning an idea like blockchain innovation, not to mention decentralized finance (DeFi). As interest in DeFi finance and NFTs skyrockets, I felt it was essential to contact a lady who has devoted her time and energy to bringing ladies into DeFi explicitly. I plunked down with Maggie Love, originator of SheFi, a Decentralized Finance (DeFi) schooling activity for ladies that likewise serves as a vehicle to give assets to philanthropies that instruct ladies in STEM programs. She is likewise Co-originator and Director of Business Development at W3BCLOUD, a joint endeavor between Advanced Micro Devices (NASDAQ:AMD) and ConsenSys. 
In this meeting, we cover points about Maggie's motivation to begin SheFi close by her normal everyday employment at W3BCLOUD, why she picked Instagram as her mechanism of correspondence (Crypto notoriously lives on Twitter) and about her arrangements for SheFi's future.
What’s the story behind SheFi?
Everything began a bright summer day in 2019, stopping for a moment to talk with Corbin Page in the ConsenSys NY base camp. He educated me concerning a gathering of his ConsenSys representatives meeting up to wager on the NCAA ball competition title. Every individual places a touch of cash into the pot with the expectation of all triumphant continues going to the victor. However, this time, they took a stab at something else — as the competition went on, their cash gathered revenue on Compound, an algorithmic, self-governing loan fee convention. 
Around that time, I was at that point considering approaches to get more ladies engaged with DeFi and getting a touch more open to playing and exploring different avenues regarding cash. I was checking out the environment and not seeing numerous ladies building or playing with DeFi. I needed to be certain the new monetary worldview crypto was making included ladies all along — not sometime later. That discussion with Corbin started a thought, "Why not beginning a ladies centered DeFi investigation gathering? We could give our profit to charities that teach ladies in STEM programs!" When I thought about the name SheFi during one of my morning runs, I realized I needed to begin it and started working out the vision, mission, objectives, and construction in the fall and winter of 2019. 
I dispatched SheFi openly in the spring of 2020. I directed the meetings with a gathering of ladies in the crypto space however not in DeFi. In the fall of 2020, I began a SheFi partner through a crypto social club I am essential for called Mochi with ~20 ladies. In equal, I shared an encouragement to join the third SheFi companion on Twitter and the SheFi site, and ~40 ladies joined, going from people that were absolutely new to crypto to ladies with halfway crypto information yet curious about DeFi. 
Presently, after a year, SheFi is teaching ~60+ ladies through two accomplices. It's rousing to see such countless achieved ladies join SheFi. Between the two partners, SheFi has ladies from SHE256, RBC, Pantera Capital, IBM, Accenture, DoorDash, Apple, and Google. We likewise have business visionaries, craftsmen, specialists and advisors in the blend — SheFi truly has a different gathering of foundations and psyches. You don't have a particular foundation or experience to be important for SheFi. My solitary necessity is that all ladies consent to cultivate a local area that is strong, kind and aware.
What are SheFi’s goals?
SheFi has a couple of fundamental objectives that help its vision of a monetary economy based on Web 3.0 in which ladies are dynamic members and pioneers, consequently making a more comprehensive, different, and supportable industry. 
Engage ladies to take an interest in decentralized account conventions 
Instruct ladies on decentralized money undertakings and apparatuses 
Analysis with various decentralized money conventions and tasks 
Make a worldwide local area of ladies who can advance the appropriation of DeFi among banked, underbanked, and unbanked ladies internationally 
I likewise trust that through finding out about decentralized money, the ladies feel more enabled communicating with the customary monetary world. SheFi's exercises are set up in a conversational, congenial way. No inquiries are viewed as terrible inquiries. In the event that we happen upon a term that has establishes in institutional money, we return and DeFine (see what I did there?) that term and spot it inside the appropriate setting. 
We will likely assistance ladies sort out crypto as a venture just as a monetary resource, while clarifying the numerous things they can be utilized for. The chances are perpetual, and that could likewise be off-putting. Numerous individuals experience decision over-burden once entering the space. Normal inquiries posed include: "Would it be a good idea for me to put my crypto resources in BlockFi, a stage that gives crypto bank accounts and crypto-upheld credits? What might be said about AAVE? Should my resources sit in MetaMask?" 
SheFi is clear to emphasize that decentralization is very fundamental, yet this is likewise your cash. Monetary danger levels fluctuate from one individual to another. Create the resources and open doors work for your monetary goals.
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bentuckett1997 · 8 months ago
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Billboard as follows:
- Giselle @ the Winnipeg Ballet - Thursday 7th - Sunday 10th.
- Winnipeg Christmas Market @ RBC Convention Center - Nov 28th - December 1st.
- Southern Chiefs Organization celebrates their 25th Anniversary, with a commemoration of First Nations Veterans.
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orbemnews · 4 years ago
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Volvo Will Convert to Electric Vehicles Faster Than Its Rivals: Live Updates Here’s what you need to know: Hakan Samuelsson, the chief executive of Volvo Cars, at an auto show in 2018. He said on Tuesday that Volvo’s electric models would be sold exclusively online.Credit…Pierre Albouy/Reuters Volvo Cars said it would convert its entire lineup to battery power by 2030, phasing out internal combustion engine vehicles faster than other automakers like General Motors. Volvo, based in Sweden and owned by Geely Holding of China, has been ahead of larger rivals in converting to electric power. In 2019, all the models it sold were either hybrids or ran solely on batteries. By 2030, Volvo will “phase out any car in its global portfolio with an internal combustion engine, including hybrids,” the company said in a statement on Tuesday. Hybrids have better fuel economy than conventional vehicles, but they may not be much better for the climate or for urban air quality if drivers do not use the electric capabilities. G.M.’s promise to sell only emission-free vehicles, which it made in January, does not take effect until 2035. Volvo acknowledged that it was responding in part to pressure from governments, many of which have announced bans on internal combustion engines in coming years. The company said its decision was based “on the expectation that legislation as well as a rapid expansion of accessible high quality charging infrastructure will accelerate consumer acceptance of fully electric cars.” In another break from industry practice, Volvo’s electric models will be sold exclusively online, bypassing dealers. “Instead of investing in a shrinking business, we choose to invest in the future — electric and online,” Hakan Samuelsson, the chief executive of Volvo, said in a statement. University of Hawaii employees monitor a Board of Regents meeting via Zoom. The teleconference company’s revenue surged more than 300 percent in its fiscal year.Credit…Audrey Mcavoy/Associated Press U.S. markets Stocks were set to drop on Tuesday after benchmark indexes recorded their best day in months on Monday. Wall Street futures indicated the S&P 500 would open about 0.3 percent weaker. On Monday, it gained 2.4 percent, the most since June. The Nasdaq and Dow indexes rose the most since early November. Traders are recovering from a volatile few days when a sell-off in government bonds rattled the equity market. On Monday, the rout eased but now bond yields are pushing higher again. The yield on 10-year U.S. Treasury notes rose 3 basis points, or 0.03 percentage point, to 1.45 percent on Tuesday. Analysts at RBC Capital Markets said markets had been testing the central banks’ resolve to keep interest rates low globally and that policymakers would have to take action to drive this message home. “However, we remain convinced that the structural upward pressure on yields remains,” they wrote in a note. “The reopening of the economies coupled with sizable fiscal spending programs and supply constraints will make it difficult for bond markets” to gain. Bond prices rise when their yields decline. Shares in Zoom rose nearly 9 percent in premarket trading after the video conferencing company said its revenue surged 326 percent in its past fiscal year to $2.65 billion. Europe Stock indexes across Europe were mostly higher. The Stoxx 600 Europe gained 0.3 percent. The annual inflation rate for the eurozone was 0.9 percent in February, the same as the previous month and in line with economists’ expectations, data published Tuesday showed. “These numbers represent the calm before the storm,” Claus Vistesen, an economist at Pantheon Macroeconomics, wrote in a note. In a few months, he wrote, inflation will jump to reflect the change in energy prices over the past year. Shares in Taylor Wimpey, a British homebuilder, rose more than 2 percent. It reported a drop in revenue in line with expectations but expects to recover as Britain emerges from lockdown. It also set aside 125 million pounds ($174 million) to fix cladding and complete other fire-safety work on buildings it put up in the past two decades. Thousands of apartment blocks in Britain are clad in flammable material, which has made them dangerous and nearly impossible to sell or refinance. Asia Most stock indexes in Asia dropped after China’s top financial regulator said that the high leverage in the financial system needed to be reduced. Guo Shuqing said he was “very worried” about bubbles in China’s property sector and that bubbles in U.S. and European markets could burst. Amazon has posted signs in its fulfillment center in Bessemer, Ala., and held meetings with workers, urging them not to unionize.Credit…Wes Frazer for The New York Times A unionizing campaign that had deliberately stayed under the radar for months has in recent days blossomed into a star-studded showdown to influence the workers. On one side is the Retail, Wholesale and Department Store Union and its many pro-labor allies in the worlds of politics, sports and Hollywood. On the other is one of the world’s dominant companies, an e-commerce behemoth that has warded off previous unionizing efforts at its U.S. facilities over its more than 25-year history: Amazon. The attention is turning this union vote into a referendum not just on working conditions at Amazon’s warehouse in Bessemer, Ala., which employs 5,800, but on the plight of low-wage employees and workers of color in particular, Michael Corkery and Karen Weise report for The New York Times. Many of the employees in the Alabama warehouse are Black, a fact that the union organizers have highlighted in their campaign seeking to link the vote to the struggle for civil rights in the South. The warehouse workers began voting by mail on Feb. 8 and the ballots are due at the end of this month. A union can form if a majority of the votes cast favor such a move. Amazon’s countercampaign, both inside the warehouse and on a national stage, has zeroed in on pure economics: that its starting wage is $15 an hour, plus benefits. That is far more than its competitors in Alabama, where the minimum wage is $7.25 an hour. “It’s important that employees understand the facts of joining a union,” Heather Knox, an Amazon spokeswoman, said in a statement. The situation is getting testy, with union leaders accusing Amazon of a series of “union-busting” tactics. The company has posted signs across the warehouse, next to hand sanitizing stations and even in bathroom stalls. It sends regular texts and emails, pointing out the problems with unions. It posts photos of workers in Bessemer on the internal company app saying how much they love Amazon. Thermal scanners check every visitor to the Student Union Building at the University of Idaho in Moscow, Idaho. So far, only 10 people have been turned away and instructed to get a coronavirus test.Credit…Rajah Bose for The New York Times The University of Idaho is one of hundreds of colleges and universities that adopted fever scanners, symptom checkers, wearable heart-rate monitors and other new Covid-screening technologies this school year. Such tools often cost less than a more validated health intervention: frequent virus testing of all students. They also help colleges showcase their pandemic safety efforts. But so far the fever scanners, which look like airport metal detectors and detect skin temperature, have flagged fewer than 10 people out of the 9,000 students living on or near campus, Natasha Singer and Kellen Browning report for The New York Times. Even then, university administrators could not say whether the technology had been effective because they have not tracked those students to see if they went on to get tested for the virus. One problem is that temperature scanners and symptom-checking apps cannot catch the estimated 40 percent of people with the coronavirus who do not have symptoms but are still infectious. Temperature scanners can also be wildly inaccurate. Administrators at Idaho and other universities said their schools were using the new tech, along with policies like social distancing, as part of larger campus efforts to hinder the virus. Some said it was important for their schools to deploy the screening tools even if they were only moderately useful. At the very least, they said, using services like daily symptom-checking apps may reassure students and remind them to be vigilant about other measures, like mask wearing. Some public health experts said it was understandable that colleges had not methodically assessed the technology’s effectiveness against the coronavirus. After all, they said, schools are unaccustomed to frequently screening their entire campus populations for new infectious diseases. Even so, some experts said they were troubled that universities lacked important information that might help them make more evidence-based decisions on health screening. “It’s a massive data vacuum,” said Saskia Popescu, an infectious-disease epidemiologist who is an assistant professor at George Mason University. “The moral of the story is you can’t just invest in this tech without having a validation process behind it.” Source link Orbem News #Convert #Electric #Faster #Live #Rivals #Updates #Vehicles #Volvo
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frankkjonestx · 5 years ago
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A spherical star cluster has surprisingly few heavy elements
A strange, newly measured clump of stars orbiting the nearby Andromeda galaxy has the lowest level of heavy chemical elements ever seen in one of these mysterious star clusters. Named RBC EXT8, this globular cluster is also surprisingly massive, challenging theories for how such clusters and some galaxies form, astronomers report online October 15 in Science.
“It’s a very unusual object,” says astrophysicist Oleg Gnedin of the University of Michigan in Ann Arbor, who was not involved in the new discovery.
Globular clusters are crowded, spherical collections of stars that orbit a galaxy’s center, though most, including RBC EXT8, live in the galactic outskirts. The clusters are typically billions of years old, so their stars tend to be chemically pristine, meaning they formed before the universe had time to create much of any of the elements heavier than hydrogen or helium, which astronomers lump together as “metals.”
Previous observations of these clusters in the Milky Way and other galaxies had suggested that there’s a limit to how low a globular cluster’s metal content can be. The most metal-poor clusters were about 300 times less rich in heavy elements like iron than the sun, but no less.
But spectra of RBC EXT8, some 2.5 million light-years away, show that the cluster’s metal content is about 800 times less than the sun’s. The globular cluster that held the previous record for lowest “metallicity” has three times that amount.
“It was completely unexpected that we would find a globular cluster that is so metal poor,” says astronomer Søren Larsen of Radboud University in Nijmegen, the Netherlands.
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The bigger, fuzzy blob in the inset image at left is RBC EXT8, a globular cluster that orbits about 88,000 light-years from the center of the galaxy Andromeda (shown at right). The cluster has surprisingly few heavy elements for its size, a new study finds.© 2020 ESASky, CFHT
What’s more, given its metal-poor status, this cluster is surprisingly massive, weighing about 1.14 million times the mass of the sun. (A mid-weight globular cluster is about 100,000 solar masses, but some clusters reach 3 million solar masses. RBC EXT8 is heavy, but not the heaviest.)
That mass makes the cluster even harder to explain because across the cosmos, the more massive a galaxy or cluster is, the more heavy elements it normally has.
There are several potential explanations for that trend, but one is simply that more massive galaxies or globular clusters have more stars. A star fuses heavy elements in its core and sprinkles them around its host cluster or galaxy as it ages. Sufficiently massive stars can explode in a supernova, spreading those metals to become part of the next generation of stars (SN: 8/9/19). So more stars means more opportunity for metals to accumulate locally.
More massive objects also have the advantage of gravity, which lets them better hold on to the metals that they do have and remain a cohesive group for billions of years. Less massive globular clusters dissolve into their host galaxies over time.
Those trends together could have explained the apparent “metallicity floor” for globular clusters — all of the less massive, more metal-poor clusters have broken apart over the eons.
RBC EXT8 turns that conventional wisdom on its head. “It’s too big to have as low metallicity as it has,” Gnedin says. “That’s the conundrum.”
Astronomers aren’t sure how globular clusters form in general, but they probably grow within galaxies, rather than forming outside of them and being pulled in later. And so the clusters reflect the characteristics of their galaxies: small, metal-poor galaxies end up with small metal-poor globular clusters, and vice versa. But based on RBC EXT8’s metal content, it’s galactic birthplace would be less than a million solar masses, so smaller than the globular cluster itself – which is a paradox.
As a result, the cluster challenges some simplified models of galaxy formation. But it doesn’t completely break them, Gnedin says. “It’s one object, it’s not going to overturn things,” he says. “It just makes us people working on these issues have to work harder” and be more open-minded about other ways that galaxies could form.
Open-mindedness and willingness to explore is perhaps responsible for the new finding about RBC EXT8’s metals. Larsen and colleagues spotted the globular cluster at the beginning of a night of observing with the Keck telescope in Hawaii in October 2019. “It was really a serendipitous discovery,” he says. He had a spare hour before the globular clusters in galaxy M33 that his team was planning to look at rose above the horizon, so the observers picked another cluster “more or less at random” to fill the time.
“At first, I couldn’t really believe that what was coming out [in the observations] was right,” Larsen says. “But I kept working on it, and it turned out to hold up.”
from Tips By Frank https://www.sciencenews.org/article/globular-star-cluster-surprising-few-heavy-elements
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fireofgodottawa · 6 years ago
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Powerful time this weekend in winnipeg at the RBC CONVENTION CENTER- thousands in attendance - lives touched, healed and restored!! #thisisfireofgod #highexpectations #revival #revivalmeetings #miraclesstillhappen #winnipeg (at RBC Convention Centre Winnipeg) https://www.instagram.com/p/B3pcKUvB9fW/?igshid=1w6qg6jyv8ei
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biomedgrid · 6 years ago
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Biomed Grid | The Economic Burden of Bleeds and Transfusions in Selected Surgeries: A Retrospective Multi Center Analysis from the US Perspective
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Abstract
Objective: To identify the economic impact of bleeds and transfusions by analyzing the effect of hemostatic agents (active and passive) on adults undergoing Cardio Vascular/Thoracic & Ortho-Ortho Spine surgeries in US hospitals.
Methods: A Retrospective review of intraoperative data from 72 Cardio Vascular/Thoracic, and 39 Ortho-Ortho Spine surgeries performed between August–December 2018, from different US Urban Hospitals was performed to determine the economic impact of bleeding and transfusions associated with the utilization efficiency of active or passive hemostatic agents.
Results: Of the 111 cases analyzed, 157 hemostatic agents were used. Utilization efficiency (a percentage defined as the amount of product used divided by the amount opened) was calculated. Utilization efficiency or products such as Flowable were 84% and Sealants 97%, Products with medium utilization efficiency such as Gelatin Powder were 76% and Oxidized Cellulose 72%, and products with a low utilization efficiency such as Thrombin were 46%, and Gelatin Sponge & Bone Wax 42%. The average estimated blood loss for all surgeries was 455 mL. The total blood product units used included Packed Red Blood Cells (PRBC) 12U, Fresh Frozen Plasma (FFP) and Platelets 10U, and Cryoprecipitate 52U. The economic impact of bleeding and transfusions ranged from $9,824 to $29,296 depending on the surgery and the hemostatic agent used.
Conclusions: Surgical bleeds and transfusions can have substantial financial and medical consequences. Using appropriate hemostatic agents intraoperatively may potentially reduce bleeds requiring transfusion and likely improve patient post-surgical outcomes. The use of active hemostatic agents resulted in a substantial Blood Product Use savings of $19,472 (50%) per patient. The use of active hemostatic agents may result in effective and cost-beneficial outcomes compared with passive hemostatic agents.
Clinical relevance: The use of Active Hemostat Agents may result in better clinical and possibly economic (bleeding and transfusion) outcomes in Cardio Vascular/Thoracic & Ortho-Ortho Spine surgeries.  
Keywords:Hemostatic agents; Active and passive; LUR; Bleeds; Transfusions
Introduction
Bleeding is a complication of surgery that may lead to substantial morbidity and mortality. In different type of surgeries (CV, Vascular, Thoracic, Neuro/Neuro-Spine), severe bleeding occurs in approximately 7% of cases [1] and is associated with an increased risk of post-operative mortality [1]. The burden of bleeding in the United States is costly for patients and for the healthcare system. Patients with uncontrolled intraoperative bleeding can be four times more likely to die from a surgical procedure [4]. These patients receive more blood transfusions, have longer hospital stays and have statistically worse outcomes, including significantly higher morbidity rates. The American Medical Association and the Joint Commission have identified blood transfusions as one of the top five over-utilized therapeutic procedures in the U.S. [4]. Efficient surgeries with limited bleeding may be one potential solution. Notable National Health Organizations have begun to address the issue of how to ensure more efficient utilization of blood transfusions.
Bleeding is an anticipated consequence of virtually all types of surgical procedures. Ideally, every surgical procedure concludes with hemostasis of the surgical field and an optimal patient outcome. The rates of bleeding and bleeding-related complications ranged from 7.5% with reproductive organ procedures to 47.4% with cardiac procedures [4]. Blood transfusions are a common practice in hospitals around the world, where up to 20% of patients who undergone surgery and 35% of patients in intensive care units receive at least one blood transfusion [5,6]. Depending on the bleeding type and the quantity of blood loss, this can lead to substantial morbidity and mortality. The rates of bleeding and bleeding-related complications (hemorrhage, anemia, thrombocytopenia, hematoma, embolic events or venous thrombosis) ranged from 7.5% with reproductive organ procedures to 47.4% with cardiac procedures [7]. Using Blood Products in those high-risk bleeding surgeries can lead to costa ranging from 2,805-$17,279 for reproductive organ and spinal. Patients with bleeding-related complications and/or blood product transfusions experienced longer hospital stay (4.9-18.7 vs. 2.6-9.1 mean days) and spent more time in the ICU (0.2-8.9 vs. 0.04-1.2 mean days) compared to patients without these events [8].
Patients who receive blood transfusions have a substantially higher risk of adverse events, resulting in up to three times longer hospital stays compared to patients who do not receive transfusions. Furthermore, blood transfusions are expensive, given not only the cost of the product, but also the substantial expense of labor associated with blood management. Although necessary in terms of care and its quality, these transfusions involve significant costs. In 2008, four different studies were carried out in the United States which concluded that the costs of blood bags alone varied between $332 and $717 [9,10].
The complexity of surgical procedures, where blood loss can have devastating consequences, creates challenges for a hospital’s resources. If not well managed, intraoperative bleeding can threaten patient near-term and long-term outcomes and expend unnecessary hospital resources. Blood transfusions have become an increasingly frequent practice in U.S. hospitals. In fact, between 1997 and 2011, blood transfusions increased 134 percent. Current estimates show that as many as 40 to 50 percent of blood transfusions may be unnecessary, potentially putting patients’ lives in jeopardy, and could be costing individual hospitals as much as $1 million per year [11,12]. In addition to the supply limitations on blood and the costs associated with transfusions, transfusions may lead to suboptimal patient outcomes. Blood transfusions are frequently associated with longer patient length of stay, increased mortality and morbidity, in addition to increased costs and resource utilization. Reducing the need for blood transfusions by reducing blood loss during surgery, is one solution to eliminate wasteful utilization of resources, likely improve patient post-surgical outcomes and reduce costs to the hospital.
Blood conservation strategies are associated with nearly half the perioperative morbidity of conventional management (39.1% vs. 23.5%, p=0.046), as assessed by a composite of any of 10 major postoperative complications [13]. The implementation of new methods, supported by innovations in medical technology that allow for the continuous measurement of hemoglobin values, would facilitate decision-making regarding transfusions, allowing transfusions where medically necessary and at the right moment, therefore reducing unnecessary transfusions [14].
Methods
A Retrospective analysis intraoperative data for 72 Cardio Vascular/Thoracic procedures and 39 Ortho-Ortho Spine surgeries performed between August and December 2018, from different US Urban Hospitals, whereby, the quantity of bleeding and transfusions associated with the utilization efficiency of active or passive hemostat products was analyzed to determine the economic impact of bleeds and transfusions.
Data Source
Data for this retrospective analysis was obtained from the Live Utilization Review (LUR) US Vitale Edge Data Base Program, a repository of product utilization efficiency, estimated blood loss (EBL), economic and resource use data developed for quality and utilization benchmarking purposes.
The database includes National US representative hospital data based on bed size, geographic region, and teaching hospital status. The database comprises data from 111 cases analyzed (72 Cardio Vascular/Thoracic & 39 Ortho-Ortho Spine surgeries) and 157 hemostatic agents from August-December 2018.
Database Case Selection Criteria
The records of the Cardio Vascular/Thoracic & Ortho-Ortho Spine surgeries included in this retrospective of prospectively collected intraoperative database analysis were of patients that underwent elective or urgent surgeries performed between August- December 2018, from different US Urban Hospitals.
Data Extracted for Analyses
Data regarding surgery types [(Cardio Vascular/Thoracic & Ortho-Ortho Spine), hemostatic agents (active and passive)], energy device, EBL, cell saver used, total blood product units used (packed red blood cells (PRBC), fresh frozen plasma (FFP), platelets and cryoprecipitate) were extracted. Hemostatic agent (active and passive) utilization efficiency was calculated as a percentage defined as the amount of product used divided by the amount opened (Table 1).
Table 1:Hemostatic agent utilization.
Source: Own elaboration with data from US Vital Edge Program, LUR Analyses retrospective analysis.
Statistical Analyses
Hypothesis tests were not made, derived from the conformation on the observational data, full inhibition of bleeding was not assessed with the setup of active/passive hemostatic agents, correlation matrix and linear regression was performed in order to represent the effect of the usage of active and passive hemostatic in the EBL, linear regression showed that the use of active hemostatic agents improve 5 more times the reduction of blood lost (mL).
Methodology
Cost Analyses
Cost analysis was performed by examining the cost (system cost) of using Blood Products (RBC, Platelets, FFP and Cryoprecipitates) from the Society for the Advancement of Blood Management 2018 and Transfusions and Their Costs: Managing Patients Needs and Hospitals Economics, J Basha, R Dewitt, D Cable, G Jones. Transfusions and Their Costs: Managing Patients Needs and Hospitals Economics. The Internet Journal of Emergency and Intensive Care Medicine 2005. The first data entered the matrix were the ratio of units transfused per patient depending on the type of surgeries analyzed, the EBL and the cost of Blood Products used per surgery type and hemostatic product used (active or passive). To create the cost–benefit matrix, the savings obtained from the number of units transfused per surgery type were considered. These savings were classified by different types of surgeries identified by the ratio of units transfused. The total cost of Blood Products used was analysed with the EBL per surgery and hemostatic product (active or passive) used versus those without EBL per surgery and hemostatic product (active or passive used).
Model analyses
This model estimated the results from a retrospective analysis of prospectively collected intraoperative data (72 Cardio Vascular/ Thoracic & 39 Ortho-Ortho Spine surgeries), performed between August-December 2018, from different US Urban Hospitals; the quantity of bleeding and transfusions associated with the utilization efficiency of active or passive hemostat products was analyzed to determine the economic impact of bleeds and transfusions.The cost analysis was performed by examining the cost (system cost) of using Blood Products (RBC, Platelets, FFP and Cryoprecipitates.
Results
Of the 111 cases analyzed, 157 hemostatic agents were used; utilization efficiency (a percentage defined as the amount of product used divided by the amount opened). Utilization efficiency for products such as Flowable 84% and Sealants 97%. Products with medium utilization efficiency included Gelatin Powder76% and Oxidized Cellulose72%. Products with a low utilization efficiency included Thrombin 46%, Gelatin Sponge & Bone Wax 42% (Figure 1). The average estimated blood loss for all surgeries was 455 mL and the total blood product units used included Packed Red Blood Cells (PRBC) 12U, Fresh Frozen Plasma (FFP) and Platelets 10U, and Cryoprecipitate 52U. The average EBL for CV was 631mL, Vascular 479mL, Thoracic 402mL and Orto/Ortho-Spine 358mL, the % of cases requiring any blood transfusion by category was: CV 13.1%, Vascular 13.33% and Thoracic//Ortho/Ortho-Spine 0% and number of cases using cell salvage were: CV 32, Orto/ Ortho-Spine 2 and Vascular/Thoracic 0 (Table 2). The economic impact of bleeding and transfusions ranged from $9,824 to $29,296 depending on the surgery and the hemostatic agent used.
Source: Own elaboration with data from US Vital Edge Program, LUR Analyses retrospective analysis.
Figure 1: Utilization Efficiency by Specialty.
Table 2: Estimated Blood Los and Cell Salvage Used.
Source: Own elaboration with data from US Vital Edge Program, LUR Analyses retrospective analysis.
Discussion
The complexity of surgical procedures in an aging population, where intraoperative blood loss can have devastating consequences, creates challenges for hospital’ resources and, if not well managed, intraoperative bleeding in complex procedures can threaten patient near-term and long-term outcomes and expend unnecessary hospital resources. To address these dynamics and the challenges they present, associations, hospitals, surgeons, and policymakers must consider opportunities to drive new efficiencies in healthcare delivery to optimize patient outcomes. This is particularly important in high-risk surgeries. While there are several ways to create surgical efficiencies, and improve health outcomes, efficiencies that drive lower utilization of blood can indicate adoption of sustainable improvement initiatives across the hospital, resulting in better post-operative outcomes.
In a first step, established and respected institutions like the Society of Thoracic Surgeons, American Society of Anesthesiologists, The Joint Commission, the U.S. Department of Health and Human Services and others have recognized the importance of improving blood management and have proposed clinical guidelines to reduce the need for intraoperative transfusions through preoperative, intra-operative, and post-operative evidence-based recommendations. Beside the above strategies, it is important to choose the proper hemostatic agent (active product) to control/ stop the bleeding and reduce minor or major compactions related to bleeds. It is known that the use of active products can lead to improved intraoperative and postoperative transfusion requirements. Cost calculations reported here are hypothesis generating, do not represent a detailed or formal analysis of cost effectiveness and warrant further confirmation in dedicated economic studies. Nevertheless, based on the estimated $19,472 (50%) per patient cost saving associated with the use of hemostatic agents (active products), it seems that substantial reductions observed for some of the surgical requirements may have directly translated into cost savings (Figure 2).
Figure 2: Economic Impact of Passive and Active Hemostatic Agents of Blood Product Used.
Limitations
All economic models are a simplification of a complex healthcare situation and, hence, bear the limitations associated with a simple representation of the reality. Limitations of the analysis includes it is a retrospective analysis of an observational collected intraoperative data (72 Cardio Vascular/Thoracic & 39 Ortho Ortho Spine surgeries), performed between August-December 2018, from different US Urban Hospitals database design, which is less robust than the conduct of prospective randomized trials and inherently associated with selection biases. In addition, the sample size analyzed Cardio Vascular/Thoracic and Ortho-Spine; if we include other surgical specialties the results may be due to chance. To avoid this, a randomized clinical trial with a larger number of patients and proper measuring on the clinical impact of inhibited blood loss during procedures and the complications derived from this should be carried out.
Conclusion
Surgical bleeds, leakages and transfusions can have substantial financial and medical outcome consequences, the prevention of which would be beneficial for institutions and patients. Reducing the need for blood transfusions by minimizing blood loss during surgery through the efficient use of appropriate hemostat agents could potentially eliminate the wasteful utilization of resources and likely improve patient post-surgical outcomes. The use of hemostatic agents (active products) resulted in a substantial Blood Product Use savings of $19,472 (50%) per patient. The use of hemostatic agents (active products) may result in effective and cost-beneficial as compared with hemostatic agents (passive products) (Table 3).
Table 3: Total Cost Savings of Blood Products Use.
Acknowledgement/Conflict of interest disclosures
Authors (MGR, GFC and MAR) are employees of Baxter Healthcare, which are involved in the manufacture of a product examined in this analysis.
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thereviewsarein · 5 years ago
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Canadian rock heavyweights Big Wreck, Headstones, Moist, and The Tea Party are getting together and hitting the road this summer on the Saints And Sinners 2020 Tour, and it’s going to be loud and a lot of fun.
The 17-date summer tour starts in late June and runs through July from coast-to-coast, dipping into Buffalo for a stop as well. It’s the first time the four acts will tour together, bringing their decades of hits and experience to the same stage for rock and roll fans night after night. In a press release announcing the tour, Moist’s David Usher said, “Every night, in every city will be an amazing experience and that definitely goes for the bands too. We’ve been on festivals and tours together over the years, but this unique shared bill with all four acts in a different order every night is going to be killer. We can’t wait to get this rolling!”
We love that quote, because we know from experience that when the artists are having fun, the shows get an extra boost of energy and awesomeness.
Related: Canadian Rock & Roll Quiz!
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In the same press release, Big Wreck lead singer Ian Thornley said, “It’s going to be so much fun getting out there with these guys every night. That’s a lot of hits, and a lot of rock n’ roll. What a show… it’s going to be a big summer!” And The Tea Party’s Jeff Martin added, “I’m not sure that there’s a single concert goer out there that can handle what’s going to happen when all 4 of our bands are firing on all cylinder’s night after night. This is a tour not to be missed. Mark my words.”
Related: Ian Fletcher Thornley – Secrets at The Mod Club
The tour starts out west with four shows in British Columbia and ends down east with stops in Nova Scotia, New Brunswick, before ending at the George Street Festival in St. John’s Newfoundland. In Calgary, they’ll play at the Big Four Roadhouse during the Calgary Stampede, and in Ottawa they’ll take the stage at RBC Ottawa Bluesfest. It’s a packed schedule.
Presale tickets and VIP passes for the Saints And Sinners 2020 Tour start January 21 with general sale starting at 10 am local time on Friday, January 24. If you’re a Canadian rock and roll fan, this is a VIP package you’re going to want to consider. For $99, fans can add a photo opportunity with you and all four bands, Exclusive VIP Commemorative Saints and Sinners 2020 Tour Laminate, Exclusive Saints and Sinners 2020 Tour Lanyard, Limited Edition Pin-Pack (includes 4 Pins, 1 from each band), Exclusive Saints and Sinners 2020 Tour Drink Koozie, Front of the line access to the venue for VIP pass holder, and Early access to merch booth for VIP pass holder. Please note that not all features are available at all stops.
Click Here for ticket and VIP pass information!
The bands have also come together to do some good for the Canadian music community, committing $1 from each ticket to the Unison Benevolent Fund through PLUS1. The donations will help Canadian musicians when they need it most and it’s fantastic to see all of these acts commit to helping their fellow artists.
In the words of Headstone’s Hugh Dillon when talking about putting this show together, “These bands, coast to coast, summer 2020, where the %#@ do we sign up!! Are you kidding me, this is a once in a lifetime Rock & Roll show.” 
Related: Headstones at Toronto’s The Phoenix
Check the dates and don’t miss out on the Saints And Sinners 2020 Tour this summer!
Saints And Sinners 2020 Tour Dates
6/26/20 – Penticton, BC – South Okanagan Events Centre 6/27/20 – Abbotsford, BC – Abbotsford Centre 6/29/20 – Victoria, BC – Save On Foods Memorial Centre 7/01/20 – Prince George, BC – CN Centre 7/02/20 – Lethbridge, AB – ENMAX Centre 7/03/20 – Regina, SK – Brandt Centre 7/04/20 – Edmonton, AB – Edmonton Convention Centre 7/06/20 – Calgary, AB – Big Four Roadhouse (Stampede Park) 7/07/20 – Brandon, MB – Westoba Place 7/08/20 – Winnipeg, MB – Bell MTS Place 7/11/20 – Rama, ON – Casino Rama Resort 7/15/20 – Laval, QC – Place Bell 7/16/20 – Buffalo, NY – Artpark Amphitheater 7/18/20 – Ottawa, ON – RBC Ottawa Bluesfest 7/23/20 – Halifax, NS – Scotiabank Centre 7/24/20 – Moncton, NB – Casino New Brunswick 7/30/20 – St. John’s, NL – George Street Festival
Saints And Sinners Tour Set to Rock Canada in 2020! Canadian rock heavyweights Big Wreck, Headstones, Moist, and The Tea Party are getting together and hitting the road this summer on the Saints And Sinners 2020 Tour, and it's going to be loud and a lot of fun.
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oranpsychic-blog · 6 years ago
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universallyladybear · 6 years ago
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Comment Contrat Retraite ? À la retraite aux mêmes conditions que les salariés si vous avez un contrat vous avez le choix qui font la différence de la sécurité sociale droits des patients...
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