#cryostat microtome

[susanlabnic]

The Labnic Cryostat Microtome is a semi-automatic cryostat model with automatic and manual defrosting functions. The unit has a  light and smooth hand wheel with a locking device on it. The cryostat microtome operates with an input power of 650 VA. The cryostat microtome features an extra-large chamber with a freezing shelf that can hold up to 20 specimen discs.

[labnic235]

Cryostat Microtome

A cryostat microtome is a sophisticated laboratory instrument designed for the precise sectioning of frozen tissue samples. Combining freezing capabilities with precision cutting, it allows researchers and pathologists to obtain thin slices of tissue for histological examination under a microscope. This device plays a crucial role in various medical and scientific fields, enabling the study of tissue morphology, pathology, and cellular structures. Its advanced features include temperature control, adjustable cutting thickness, and ergonomic design, ensuring efficient and accurate tissue sectioning for research and diagnostic purpose.

[amos-scientific]

AST580 Fully-automatic Cryostat Microtome with Touch Screen

Transform your frozen tissue sectioning workflow with our Fully-automatic Cryostat Microtome equipped with an intuitive touch screen interface. Its advanced automation and precision guarantee swift, reliable sample preparation for precise diagnostics and research endeavors.

Description of AST580 Fully-automatic Microtome Cryostat with Touch Screen

AST580 fully automatic microtome is designed under engineering and ergonomic concepts. All the components are processed by computer numerical control.

Retraction function prevents specimen damage from blade.

Total thickness calculation.

Low temperature refrigeration system with environment friendly refrigerant R404.

Adopt UV sterilize for 30 minutes every time.

Peltier specimen clamp refrigeration can be turn On or Off manually.

Two defrosting methods: manual and automatic.

Emergency stop function: Press the red button to stop running when any emergency happens.

The high prevision unit is enclosed outside the cryostat chamber to prevent it from thermal expansion and contraction, and keeps minimum maintenance requirement.

Artificial intelligent interface is easy to learn and operate.

Touch Screen and display all information including thickness, thickness sum, controlling time, temperature, time on/off and so on.

Sleep Function: after activating this function, the temperature in cryostat chamber can be kept between -1℃ and -10℃; after stopping this function, the temperature in freeze chamber will rise to working temperature within 30 minutes.

Control panel with locking function could avoid faulty operation.

Handwheel locking function.

Wide freezing shelf can load 17 specimen cassettes simultaneously, and two of them are equipped with peltier to meet different temperatures.

Specification of AST580 Fully-automatic Microtome Cryostat with Touch Screen

Environment requirement

Temperature Range

+15℃～+30℃

Air Humidity

≤60%

Working pressure

（86～106）kPa

Nominal Voltage

220～240V AC/100～120V AC

Normal Frequency

50/60 Hz

Power

≤1000VA

Fuse

8A/20A

Safe Classify

Classify I - Type B

Lowest freeze chamber Temperature

-35±2℃

Lowest freeze shelf Temperature

-45±5℃

Lowest temperature of peltier unit on freeze shelf

-55±5℃

Lowest temperature of peltier unit on specimen clamp

-50±5℃(Working time of peltier: 15 minutes)

Electric coarse feed

Slow: 300µm/s±30µm/s

Rapid: 900µm/s±30µm/s

Section thickness range

0 to 100µm 0 to 3µm, in 0.5µm increments 3 to 10µm, in 1µm increments 10 to 20µm, in 2µm increments 20 to 100µm, in 5µm increments

Trimming thickness range

0 to 600µm 0 to 50µm, in 5µm increments 50 to 100µm, in 10µm increments 100 to 600µm, in 50µm increments

⊙Retraction

0~80µm, in 5µm increments

⊙Specimen feed

24mm ±0.2mm

⊙Vertical stroke

54mm±1mm

⊙Specimen Max

35×35mm

⊙Repositioning of blade holder base(left-right)

50±1mm

⊙Motorize cutting speed

75～230mm/s ± 10%.

Dimension

Width

715mm

Length

765mm

Height

1230mm

Weight

About 130kgs

[mastergarryblogs]

Anatomic Pathology Market Breakdown: Key Players, Trends, and Predictions

Anatomic pathology market, a cornerstone of modern medicine, plays an indispensable role in diagnosing diseases, especially those related to cancer, infections, and autoimmune disorders. By analyzing tissues and organs under a microscope, pathologists can uncover critical information that guides the treatment of patients. The global anatomic pathology market has seen substantial growth over the years and is poised for significant expansion in the coming decade. This article delves into the factors driving this growth, the latest innovations in the field, and a detailed forecast for the market's future.

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Anatomic Pathology Market Overview: Size, Growth, and Forecasts

The global anatomic pathology market has witnessed a rapid evolution, particularly between 2019 and 2022. In 2022, the market was valued at approximately $3.25 billion, reflecting steady growth despite challenges such as the COVID-19 pandemic and the geopolitical tensions stemming from the Russia-Ukraine war. As we move forward, the anatomic pathology market is projected to experience robust expansion, reaching an estimated market size of $1,374.15 billion by 2031, with a compound annual growth rate (CAGR) of 29.5% from 2024 to 2031.

This growth can be attributed to several key factors, including increasing incidences of chronic diseases like cancer, advancements in diagnostic technologies, and a growing demand for personalized medicine. Furthermore, regions like North America, Europe, and Asia-Pacific are expected to contribute significantly to this market expansion, with key players continuing to innovate in their offerings.

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Key Anatomic Pathology Market Segments in Anatomic Pathology

1. Products and Services

The products and services in the anatomic pathology market are vital for the accurate diagnosis of diseases. These products range from the instruments used in laboratories to the reagents that facilitate diagnostic processes.

Instruments

Instruments are essential to any pathology laboratory. Notable instruments include:

Microtomes & Cryostats: These are used to prepare thin sections of tissue samples for examination under a microscope. Cryostats are particularly used for frozen sectioning, which is critical for immediate diagnosis during surgery.

Tissue Processors: These devices are used to prepare biological tissue samples for analysis by embedding them in wax or other mediums.

Automatic Stainers: These automate the staining process, enhancing the visibility of tissue structures under the microscope.

Whole Slide Imaging (WSI) Scanners: These devices digitize entire tissue slides, allowing pathologists to view high-resolution images remotely, which is especially beneficial for telepathology and consultations across long distances.

Consumables

Consumables include a range of items that are integral to the workflow of a pathology lab, such as:

Reagents & Antibodies: Essential for detecting specific proteins or markers in tissues.

Probes & Kits: These are used in molecular pathology to identify genetic abnormalities.

Stains & Fixatives: Used to prepare tissue samples for microscopic examination.

Services

The services sector is a crucial component of anatomic pathology, with offerings such as:

Anatomic Pathology Services: These services focus on the analysis of tissue samples to diagnose diseases.

Consultation Services: Pathologists offer second opinions and diagnostic insights based on tissue and organ samples.

Diagnostic Kits and Reagents: These pre-packaged solutions enable pathologists to conduct specific tests more efficiently and accurately.

2. Applications of Anatomic Pathology

Anatomic pathology market spans a wide range of applications that impact multiple sectors of healthcare and research.

Clinical Diagnostics

The primary application of anatomic pathology is clinical diagnostics. Pathologists examine tissue samples from patients to diagnose diseases such as:

Cancer: Identifying the presence of malignancy in biopsied tissue.

Infectious Diseases: Analyzing tissue changes caused by infections.

Autoimmune Disorders: Examining tissues to determine the impact of autoimmune responses.

The insights derived from these diagnostic processes guide the treatment decisions for patients, ensuring a personalized approach to care.

Research

Anatomic pathology is indispensable in research, particularly in areas like disease mechanisms, drug development, and understanding cellular abnormalities. Research institutions use pathology techniques to study the progression of diseases, evaluate potential treatments, and explore new diagnostic methods.

Forensic Pathology

Forensic pathology focuses on determining the cause of death through autopsies and tissue analysis. Forensic pathologists play a crucial role in legal investigations, providing key evidence in criminal cases, accidents, or unexplained deaths.

Drug Development

In the pharmaceutical industry, anatomic pathology supports drug development by helping scientists understand how new drugs affect tissue at a cellular level. This is essential for preclinical and clinical trials, where tissue studies assess drug safety and efficacy.

3. End Users of Anatomic Pathology

Anatomic pathology services cater to several key end users in healthcare and research:

Hospitals: Pathologists within hospitals provide diagnostic support for surgeons and oncologists, especially in cancer diagnosis.

Diagnostic Laboratories: These labs process tissue samples from multiple healthcare providers, conducting large volumes of diagnostic tests.

Research Institutions: Research entities rely on anatomic pathology for understanding diseases and developing new treatments.

Forensic Facilities: Forensic pathologists analyze tissue samples in autopsies, contributing to the investigation of death causes in legal matters.

4. Geographic Segmentation

North America

North America remains one of the dominant markets for anatomic pathology, driven by a strong healthcare infrastructure, rising cancer cases, and increasing investment in diagnostic technologies. The U.S. and Canada are major players in both the demand and innovation of anatomic pathology tools.

Asia-Pacific

The Asia-Pacific region is projected to experience rapid growth due to the expanding healthcare sector, increasing awareness of cancer screenings, and improving healthcare access in countries like China, India, and Japan. This region is expected to play a pivotal role in the market's growth over the next decade.

Europe

Europe is also a significant contributor, with countries like Germany, France, and the UK leading advancements in anatomic pathology research and diagnostics. The region benefits from robust healthcare systems and high investments in medical technology.

Other Regions

Emerging markets in the Middle East, Africa, and South America are expected to contribute to the growing demand for anatomic pathology services as healthcare infrastructure improves and more individuals seek specialized medical care.

Leading Companies in Anatomic Pathology

The anatomic pathology market is competitive, with numerous key players driving innovation in instruments, consumables, and services. Prominent companies include:

Danaher Corporation: A global leader in medical technology, offering a wide range of anatomic pathology instruments and services.

Merck KGaA: A major player in laboratory reagents and diagnostic tools, particularly in molecular pathology.

BioGenex: Known for their advanced diagnostic solutions and immunohistochemistry products.

Roche: A healthcare giant offering innovative diagnostic services and molecular pathology tools.

Hologic, Inc.: Specializes in women’s health diagnostics, including breast pathology.

These companies continue to innovate and lead the market by focusing on technological advancements, improving diagnostic accuracy, and expanding their product and service portfolios.

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Conclusion: The Future of Anatomic Pathology

The anatomic pathology market is poised for remarkable growth over the next decade. As technology advances and demand for more precise, personalized diagnostics increases, the market will continue to evolve. With key players leading the way, we can expect innovations in digital pathology, molecular diagnostics, and telepathology to redefine how pathologists work and how patients receive care.

The rise in chronic diseases, particularly cancer, and the ongoing efforts in drug development and clinical research will drive an even greater demand for anatomic pathology services. As these trends unfold, the market will provide increasing opportunities for both established companies and new entrants in the field.

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[inoxcvablogs]

What is a Cryostat?

A cryostat is a device engineered to sustain cryogenic temperatures, typically ranging from -150°C (-238°F) down to absolute zero (-273°C or -460°F). These ultra-low temperatures are crucial for maintaining the structural integrity of samples, facilitating detailed microscopic analysis without degradation. The term "cryostat" derives from the Greek words "kryos" (cold) and "stat" (stable), emphasizing its role in providing a stable cold environment.​

Key Features of Cryostats

Temperature Control: Cryostats achieve and maintain specific low temperatures using refrigeration methods such as liquid nitrogen or helium. Precise temperature control is vital for experiments requiring stable conditions.

Insulated Chamber: Typically, cryostats feature a vacuum-insulated chamber that minimizes thermal exchange with the environment, ensuring consistent internal temperatures.

Microtome Integration: Many cryostats incorporate a microtome, allowing users to slice samples into thin sections for microscopic examination—a feature particularly important in histopathology.

Safety Mechanisms: Modern cryostats are equipped with safety features such as alarms and automatic shut-off systems to prevent overheating or mechanical failures.

Applications of Cryostats

Cryostats serve a multitude of purposes across various sectors:

Medical Applications

In pathology labs, cryostats are used to rapidly freeze tissue samples for examination. This rapid freezing preserves cellular structures, facilitating accurate diagnoses of diseases like cancer through histological analysis.

Scientific Research

Cryostats are essential in scientific research for studying materials at low temperatures. Fields such as molecular biology and materials science rely on cryostats to understand substance properties under cryogenic conditions, leading to significant breakthroughs.

Industrial Applications

In industries like semiconductor manufacturing, cryostats play a crucial role where precise temperature control is necessary to ensure product quality.

Types of Cryostats

Various types of cryostats are available, each suited for specific applications:

Closed-Cycle Cryostats

These systems use helium vapor and an external refrigerator to cool samples without the need for frequent refills of cryogenic fluids. They can operate continuously but require significant electrical power.

Bath Cryostats

Utilizing a bath of liquid helium or nitrogen, these cryostats cool samples directly. While they need periodic replenishment of the cryogen, they are simpler in design and operation.​

Flow Cryostats

Employing a continuous flow of coolant, flow cryostats maintain low temperatures and are often used in applications requiring constant cooling over extended periods.

Cryogen-Free Cryostats

These advanced systems use mechanical coolers instead of liquid cryogens, offering convenience by eliminating the need for refilling while providing stable low temperatures.

INOXCVA's Contribution to Cryostat Technology

In April 2023, INOXCVA achieved a significant milestone by fabricating India's first indigenously designed zero-boil-off 4K helium cryostat for a whole-body 1.5T superconducting MRI magnet system. This development is expected to reduce MRI costs and enhance healthcare accessibility in India. The project was a collaborative effort among various Indian institutions, positioning India as the sixth country globally capable of manufacturing MRI magnet systems.

Conclusion

Understanding cryostats reveals their critical role across various sectors, from healthcare to industrial applications. Advancements in technology have led to more efficient designs like closed-cycle and cryogen-free systems, expanding the utility of cryostats. Companies like INOXCVA are at the forefront of this evolution, providing essential equipment that supports scientific research and industrial processes worldwide. As we move towards a future focused on sustainability and innovation, the importance of cryogenic technology will only increase.​

[labtroscientific]

Cryostat Microtome LT-CM201

Labtro Cryostat Microtome features an ergonomic design with rounded corners. It includes a clear digital display that shows unit status, a spacious freezing chamber accommodates multiple samples. The rapid drying method ensures efficiency, and the versatile heat extractor offers flexibility.

[marialabtro]

Automatic Cryostat Microtome LT-ACM201

Labtro Cryostat Microtome features an ergonomic design with rounded corners, a stainless steel cooling chamber, and a heavy-duty compressor using CFC-free gas for -30°C. It includes fluorescent lighting, a hygiene drainage system, and a digital display for easy monitoring of unit status.

[marketprofessional]

Tissue Diagnostics Market Size, Share & Growth by 2033

Tissue Diagnostics Market Overview The Global Tissue Diagnostics Market has seen continuous development in the past couple of years and is anticipated to grow much further during the forecast period. The exploration introduces a total evaluation of the Tissue Diagnostics Market and contains Future patterns, Current Growth Factors, mindful sentiments, certainties, chronicled information, and factually bolstered and industry-approved market information.

According to Straits Research, the global Tissue Diagnostics market size was valued at USD 5185.23 Million in 2022. It is projected to reach from USD XX Million in 2023 to USD 9375.02 Million by 2031, growing at a CAGR of 6.8% during the forecast period (2023–2031).

After identifying promising candidates, they undergo extensive testing and optimization to enhance their effectiveness, safety, and pharmacokinetic properties. This entire process of Tissue Diagnostics Market may take several years and necessitates collaboration between scientists from diverse fields such as chemistry, biology, and pharmacology. Irrespective of the challenges encountered during Tissue Diagnostics Market, it has the potential to revolutionize lives by providing new treatments for various diseases.

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Competitive Analysis The report contains an in-depth analysis of the vendor’s profile, including financial health, business units, key business priorities, SWOT, strategies, and views.

Abbott Laboratories F. Hoffmann-La Roche Ltd Siemens Healthineers bioMerieux Bio SB DiaGenic Enzo Life Sciences, Inc Vitro Sa (Master Diagnóstica) Tissuegnostics Gmbh Abcam Plc Sakura Finetek Japan Co., Ltd Cell Signaling Technology, Inc The vendors have been identified based on the portfolio, geographical presence, marketing & distribution channels, revenue generation, and significant R&D investments.

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Vendors across different verticals are planning for high investments in this market, and as a result, the market is expected to grow at an impressive rate in the upcoming years. The key players are adopting various organic and inorganic growth strategies such as mergers & acquisitions, collaboration & partnerships, joint ventures, and a few other strategies to be in a strong position in the global market.

Market Segmentation Analysis The report provides a wide-ranging evaluation of the market, providing in-depth qualitative insights, historical data, and supportable projections along with the assumptions about the Tissue Diagnostics Market size. The projections featured in the report have been derived using proven research methodologies and assumptions based on the vendor’s portfolio, blogs, white papers, and vendor presentations. Thus, the research report represents every side of the Tissue Diagnostics Market and is segmented on the basis of regional markets, offerings, applications, and end-users.

By Technology IHC {Instruments [Slide Staining Systems, Tissue Microarrays, Tissue Processing Systems, Slide Scanners, Other products], Consumables [Reagents, Antibodies, Kits]} In-Situ Hybridization {Instruments, Consumables, Software} Primary and Special Staining Digital Pathology and Workflow {Whole Slide Imaging, Image Analysis Informatics, Information Management System Storage and Communication} Anatomic Pathology {Instruments [Microtomes and Cryostat microtomes, Tissue processors, Automatic strainers, Other products], Consumables [Reagents and Antibodies, Probes and Kits, Others]} By Applications Breast Cancer Prostate Cancer Gastric Cancer Non-Small Cell Lung Cancer Other Cancers By End-User Hospitals Research Laboratories Pharmaceutical Organizations Contract Research Organizations (CROs) Access Detailed Segmentation @ https://straitsresearch.com/report/tissue-diagnostics-market/segmentation

Regional Analysis for Tissue Diagnostics Market The regional analysis offers a comprehensive view of the Tissue Diagnostics Market sales and growth across global and country-level markets. It provides volume and market size data by region, with insights into growth trends in countries like the United States, Canada, Germany, France, China, Japan, and more. The analysis also covers major regions such as North America, Europe, Asia-Pacific, South America, and the Middle East & Africa.

Benefits Tissue Diagnostics Market Industry companies to ensure business continuity with powerful protection by constantly checking the report and representing attractive growth opportunities for the companies. Tissue Diagnostics Market handles all the needs of the operators by allowing them to improve their services and concentrate on their core business. Tissue Diagnostics Market Research aims to increase business agility and reduce operational and capital expenditure with improved technology rollouts and capacity planning. The report discusses service types and regions related to this Tissue Diagnostics Market. Further, the report provides details about the major challenges affecting the market growth.

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Other Features of the Report: Provides a thorough analysis of the key strategies with a focus on the corporate structure, R&D methods, localization strategies, production capabilities, sales, and performance in various companies. Provides valuable insights into the product portfolio, including product planning, development, and positioning. Thanks for reading this article; you can also get individual chapter-wise sections or region-wise report versions like North America, Europe, or Asia.

About Us: By Technology IHC {Instruments [Slide Staining Systems, Tissue Microarrays, Tissue Processing Systems, Slide Scanners, Other products], Consumables [Reagents, Antibodies, Kits]} In-Situ Hybridization {Instruments, Consumables, Software} Primary and Special Staining Digital Pathology and Workflow {Whole Slide Imaging, Image Analysis Informatics, Information Management System Storage and Communication} Anatomic Pathology {Instruments [Microtomes and Cryostat microtomes, Tissue processors, Automatic strainers, Other products], Consumables [Reagents and Antibodies, Probes and Kits, Others]} By Applications Breast Cancer Prostate Cancer Gastric Cancer Non-Small Cell Lung Cancer Other Cancers By End-User Hospitals Research Laboratories Pharmaceutical Organizations Contract Research Organizations (CROs) > StraitsResearch.com is a leading research and intelligence organization, specializing in research, analytics, and advisory services along with providing business insights & research reports.

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