#dsRNA
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Exploring the Role and Applications of dsRNA J2 Antibody in Research and Diagnostics
The dsRNA J2 antibody is a vital tool in the fields of virology, immunology, and molecular biology. This antibody specifically targets double-stranded RNA (dsRNA), a molecular pattern recognized by the immune system as a sign of viral infection. Researchers employ dsRNA J2 antibodies to study viral infections, cellular immune responses, and the mechanisms of gene expression. In this article, we’ll explore the importance, applications, and benefits of the dsRNA J2 antibody in scientific research and diagnostics.
What Is dsRNA J2 Antibody?
The DsRNA J2 Antibody is a monoclonal antibody that binds specifically to double-stranded RNA, which is often generated during viral replication. B ecause many viruses produce dsRNA as part of their life cycle, the presence of dsRNA in cells often indicates a viral infection. By using the dsRNA J2 antibody, researchers can detect and visualize dsRNA within cells, making it easier to study viral infection pathways and cellular immune responses.
Key Applications of dsRNA J2 Antibody
Virus Detection and Research One of the primary applications of the dsRNA J2 antibody is in the detection of viral infections. Researchers use it to identify viral replication sites within infected cells, helping to pinpoint where the virus is active. This is essential for understanding how viruses, like influenza, hepatitis, or coronaviruses, replicate and spread within the host.
Immunology Studies The immune system recognizes dsRNA as a "danger signal," triggering a response to eliminate the infection. The dsRNA J2 antibody allows researchers to study these immune pathways in detail, examining how cells detect dsRNA and how they respond to viral presence. This is crucial in developing treatments that can strengthen or regulate the immune response.
Gene Silencing and RNA Interference (RNAi) In gene silencing studies, dsRNA plays a significant role. RNA interference, a natural cellular process, uses dsRNA to silence specific genes. The dsRNA J2 antibody helps researchers track the activity of dsRNA within cells, aiding in studies of gene function and expression.
Advantages of Using dsRNA J2 Antibody
The dsRNA J2 antibody is a precise and reliable tool in research. It offers high specificity, reducing background noise in assays and ensuring that results are accurate. Additionally, it is compatible with various laboratory techniques, including immunofluorescence and Western blotting.
Conclusion
The dsRNA J2 antibody is invaluable in virology, immunology, and gene expression research, making it easier to detect viral infections, study immune responses, and understand gene-silencing mechanisms. Its specificity and versatility have made it a trusted tool in laboratories worldwide, advancing our understanding of cellular responses to infection and disease.
#dsrna antibody j2#mab-based elisa#panitumumab elisa#semaglutide elisa#dsrna j2 antibody#dsrna elisa#cytokine elisa
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just yelled out the various virus genome types at my cat. having a normal one
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INTRODUCTION
At present, we do not understand precisely how the SARS-CoV-2 coronavirus induces a spectrum of immune responses in different infected hosts, including severe inflammation in some, or how post-acute infection sequelae come about. In this review, we consider a conceptual framework whereby the virus itself is a reservoir of peptide motifs with pro-inflammatory activity. These motifs can potentially be liberated by highly variable proteolytic processing by the host. We focus on the ability of viral peptide motifs that can mimic innate immune peptides (more commonly known as ‘antimicrobial peptides’ (AMPs)). AMPs (and their ‘xenoAMP’ mimics) are not themselves pathogen-associated molecular patterns (PAMPs) that activate innate immunity via recognition by host pattern recognition receptors (PRRs) but can strongly amplify PRR activation via promoting multivalent PAMP presentation. An important mechanism in the host’s immune amplification machinery and is implicated in a range of autoimmune conditions, including lupus and rheumatoid arthritis, which are among the sequelae of COVID-19. We review experiments that show AMPs and SARS-CoV-2-derived xenoAMP can assemble with PAMPs such as dsRNA into pro-inflammatory complexes, resulting in cooperative, multivalent immune recognition by PRRs and grossly amplified inflammatory responses, a phenomenon generally not observed in harmless coronavirus homologs. We also review the persistence of viral remnants from other viral infections and their association with inflammatory sequelae long after the infection has been cleared.
This is a very technical research paper which will be difficult to read with no medical background. However I did understand enough to make me take notice. The following is a quote explaining the study.
"Study of 29 ICU COVID patients shows viral fragments persist after infection, mimicking immune activators and driving inflammation, potentially explaining long COVID and post-infection syndromes." quote by thetranscendeman on X.
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Who is Geoff Pain?
Dr. Geoff Pain is a passionate and relentless Australian scientist who has been ringing alarm bells since the beginning of the COVID-19 injection rollout. Unlike paid experts toeing the government line, Pain isn’t afraid to speak out. His investigations dig deep into the murky world of vaccine contaminants—elements that were never supposed to be injected into anyone’s body. He's been publishing his research and findings on Substack, and many of us who care about truth have stood beside him. I even made a video—Deadly Betrayal—to support his work.
Now, with new evidence in hand, the time has come to say the quiet part out loud.
The Dirty Secret Hidden in the Vials
Most Australians still don’t know this: the COVID-19 mRNA injections (Pfizer and Moderna) have been found to contain genetic contaminants that were never supposed to be there—contaminants that could trigger harmful, even deadly, immune reactions. These include:
Double-stranded RNA (dsRNA) – known to provoke severe inflammation and autoimmune diseases
Bacterial DNA – a foreign genetic pollutant from the manufacturing process using E. coli bacteria
These substances are not theoretical risks. They have been measured—even acknowledged—by the manufacturers and regulatory bodies. But the public was never told.
And the Australian Therapeutic Goods Administration (TGA)? They knew. And they did next to nothing.
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Exploring RNA Interference
Imagine a molecular switch within your cells, one that can selectively turn off the production of specific proteins. This isn't science fiction; it's the power of RNA interference (RNAi), a groundbreaking biological process that has revolutionized our understanding of gene expression and holds immense potential for medicine and beyond.
The discovery of RNAi, like many scientific breakthroughs, was serendipitous. In the 1990s, Andrew Fire and Craig Mello were studying gene expression in the humble roundworm, Caenorhabditis elegans (a tiny worm). While injecting worms with DNA to study a specific gene, they observed an unexpected silencing effect - not just in the injected cells, but throughout the organism. This puzzling phenomenon, initially named "co-suppression," was later recognized as a universal mechanism: RNAi.
Their groundbreaking work, awarded the Nobel Prize in 2006, sparked a scientific revolution. Researchers delved deeper, unveiling the intricate choreography of RNAi. Double-stranded RNA molecules, the key players, bind to a protein complex called RISC (RNA-induced silencing complex). RISC, equipped with an "Argonaut" enzyme, acts as a molecular matchmaker, pairing the incoming RNA with its target messenger RNA (mRNA) - the blueprint for protein production. This recognition triggers the cleavage of the target mRNA, effectively silencing the corresponding gene.
So, how exactly does RNAi silence genes? Imagine a bustling factory where DNA blueprints are used to build protein machines. RNAi acts like a tiny conductor, wielding double-stranded RNA molecules as batons. These batons bind to specific messenger RNA (mRNA) molecules, the blueprints for proteins. Now comes the clever part: with the mRNA "marked," special molecular machines chop it up, effectively preventing protein production. This targeted silencing allows scientists to turn down the volume of specific genes, observing the resulting effects and understanding their roles in health and disease.
The intricate dance of RNAi involves several key players:dsRNA: The conductor, a long molecule with two complementary strands. Dicer: The technician, an enzyme that chops dsRNA into small interfering RNAs (siRNAs), about 20-25 nucleotides long. RNA-induced silencing complex (RISC): The ensemble, containing Argonaute proteins and the siRNA. Target mRNA: The specific "instrument" to be silenced, carrying the genetic instructions for protein synthesis.
The siRNA within RISC identifies and binds to the complementary sequence on the target mRNA. This binding triggers either:Direct cleavage: Argonaute acts like a molecular scissors, severing the mRNA, preventing protein production. Translation inhibition: RISC recruits other proteins that block ribosomes from translating the mRNA into a protein.
From Labs to Life: The Diverse Applications of RNAi
The ability to silence genes with high specificity unlocks various applications across different fields:
Unlocking Gene Function: Researchers use RNAi to study gene function in various organisms, from model systems like fruit flies to complex human cells. Silencing specific genes reveals their roles in development, disease, and other biological processes.
Therapeutic Potential: RNAi holds immense promise for treating various diseases. siRNA-based drugs are being developed to target genes involved in cancer, viral infections, neurodegenerative diseases, and more. Several clinical trials are underway, showcasing the potential for personalized medicine.
Crop Improvement: In agriculture, RNAi offers sustainable solutions for pest control and crop development. Silencing genes in insects can create pest-resistant crops, while altering plant genes can improve yield, nutritional value, and stress tolerance.
Beyond the Obvious: RNAi applications extend beyond these core areas. It's being explored for gene therapy, stem cell research, and functional genomics, pushing the boundaries of scientific exploration.
Despite its exciting potential, RNAi raises ethical concerns. Off-target effects, unintended silencing of non-target genes, and potential environmental risks need careful consideration. Open and responsible research, coupled with public discourse, is crucial to ensure we harness this powerful tool for good.
RNAi, a testament to biological elegance, has revolutionized our understanding of gene regulation and holds immense potential for transforming various fields. As advancements continue, the future of RNAi seems bright, promising to silence not just genes, but also diseases, food insecurity, and limitations in scientific exploration. The symphony of life, once thought unchangeable, now echoes with the possibility of fine-tuning its notes, thanks to the power of RNA interference.
#science sculpt#life science#science#molecular biology#biology#biotechnology#dna#double helix#genetics#artists on tumblr#rna#rna sequencing#RNA interference#cell biology#cells#biomolecules#illustrates#scientific illustration#illustration#illustrative art#scientific research
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ok but if cleo was a virud would it be a:
ssDNA
ssRNA
dsDNA
dsRNA
?
Single stranded bc you don't have a partner strand to make a helix no and ssdna bc that it wayyy more coiled like you're wayyy more gay
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RNAi is super cool and has a lot of really neat use cases, especially in treatment of disease. It's a way to protect against viruses by suppressing RNA thought to be viral in nature, especially double stranded RNA (dsRNA). Once those are recognized, and I can not stress the name of the enzyme that does this enough, Dicer cuts up the dsRNA into small chunks and another enzyme breaks them into single stranded RNAs and starts using it as a template to block mRNAs that bind to it (because they are the same) from being made into protein. What happened in the case of these petunias is that by adding an extra copy of the "make purple" instruction, the petunias freaked out and thought a virus did that, because a virus was used to do that, and the petunias stopped making purple because it thought it was a virus. It's currently being investigated for treatments for diseases like macular degeneration, HIV/AIDS, cancer and more! If you'd like to learn more, google "RNA interference" (the "i" stands for interference)
scientists in the 1990s, putting a Get More Purple gene attached to a harmless plant virus into an already purple petunia: please get more purple
the petunia, sensing an apparent honest to god Get More Purple Disease, using the previously undiscovered RNAi antiviral ability to shut down all other purple genes along with it just in case: you put VIRUS in petunia? you infect her with the More Purple?? oh! oh! her children shall bloom white! jail for mother, jail for mother for One Thousand Years!!!!
#science#it was very fun getting to learn about this in my genetics class freshman year#because its very silly how we learned about it but its also like “oh this is actually useful and an up and coming field”
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North America RNAi Therapeutics Market Trends, Size, Segment and Growth by Forecast to 2030
The North America RNAi therapeutics market is experiencing significant growth, projected to nearly double from US$ 302.77 million in 2019 to US$ 598.60 million by 2027, demonstrating a Compound Annual Growth Rate (CAGR) of 9.0% over this period.
Understanding RNA Interference (RNAi)
RNA interference (RNAi) is a fundamental biological mechanism where RNA molecules naturally suppress gene expression by neutralizing specific messenger RNA (mRNA) molecules. This process is invaluable in research, allowing scientists to selectively "switch off" genes using synthetic double-stranded RNA (dsRNA). This capability enables large-scale screens to systematically analyze the function of individual genes, aiding in the understanding of complex cellular events like cell division. Beyond research, RNAi also holds practical applications in medicine, biotechnology, and even as insecticides. 📚Download Full PDF Sample Copy of Market Report @ https://www.businessmarketinsights.com/sample/TIPRE00015136
Market Drivers and Challenges
The robust growth of the North America RNAi therapeutics market is primarily fueled by two key factors:
Growing investments in RNAi therapies: Increased funding and research into RNAi-based treatments are accelerating market expansion.
Rising prevalence of infectious diseases and chronic conditions: The urgent need for novel therapeutic solutions for a wide range of illnesses is driving demand for RNAi therapies.
However, the market faces a notable challenge:
High cost of RNAi therapy development: The significant investment required for research, development, and clinical trials of RNAi therapies can hinder market growth to some extent.
Key Market Segments
In 2019, several segments played a dominant role in the North America RNAi therapeutics market:
Molecule Type: Small interfering RNAs (siRNA) held the largest market share, indicating their prominence in current RNAi therapeutic development.
Route of Administration: Pulmonary delivery was the leading route, suggesting its effectiveness and potential for targeting respiratory and other systemic conditions.
Application: The oncology segment accounted for the largest share, highlighting the significant focus on RNAi therapies for cancer treatment.
End User: Research and academic laboratories were the primary end-users, underscoring the foundational role of these institutions in advancing RNAi research and its therapeutic applications.
Major Sources and Companies Listed
Several major primary and secondary sources associated with the North America RNAi therapeuticsmarket report are theWorld Health Organization (WHO), National Cancer Institute (NCI),Centers of Disease Control and Prevention (CDC),Asthma and Allergy Foundation of America,American Lung Association,the American Cancer Society (ACS), and others.
Reasons to buy report
It provides understanding of the North America, RNAi therapeuticsmarket landscape and identifies RNAi therapeuticsmarket segments that are most likely to guarantee a strong return.
It guides stay ahead of the race by comprehending the ever-changing competitive landscape for the North America RNAi therapeuticsmarket.
It helps efficiently plan merger and acquisition, and partnership deals in the RNAi therapeuticsmarket by identifying market segments with the most promising probable sales
It facilitates knowledgeable business decision-making through perceptive and comprehensive analysis ofRNAi therapeuticsmarket performance of various segments pertaining to the North America RNAi therapeuticsmarket.
It providesRNAi therapeuticsmarket revenue forecast of the market based on various segments for the period from 2019 to 2027.
Strategic Insights for the North America RNAi Therapeutics Market
Strategic insights into the North America RNAi therapeutics market deliver a data-driven analysis of the evolving industry landscape, highlighting current trends, leading players, and region-specific dynamics. These insights are designed to provide stakeholders—whether investors, manufacturers, or partners—with actionable guidance to gain a competitive edge. By uncovering untapped market segments and helping shape distinctive value propositions, these insights enable informed, strategic decision-making. Through the application of advanced data analytics, stakeholders can anticipate market shifts, respond proactively to industry changes, and position themselves for sustainable, long-term success. With a forward-looking approach, these insights support the achievement of business goals and profitability in one of the most dynamic and rapidly advancing therapeutic sectors.
Market leaders and key company profiles Alnylam Pharmaceuticals, Inc
Arrowhead Pharmaceuticals, Inc
Quark
Rexahn Pharmaceuticals, Inc
Arbutus Biopharma North America RNAi Therapeutics Regional Insights
The geographic scope of the North America RNAi Therapeutics refers to the specific areas in which a business operates and competes. Understanding local distinctions, such as diverse consumer preferences (e.g., demand for specific plug types or battery backup durations), varying economic conditions, and regulatory environments, is crucial for tailoring strategies to specific markets. Businesses can expand their reach by identifying underserved areas or adapting their offerings to meet local demands. A clear market focus allows for more effective resource allocation, targeted marketing campaigns, and better positioning against local competitors, ultimately driving growth in those targeted areas.
About Us: Business Market Insights is a market research platform that provides subscription service for industry and company reports. Our research team has extensive professional expertise in domains such as Electronics & Semiconductor; Aerospace & Défense; Automotive & Transportation; Energy & Power; Healthcare; Manufacturing & Construction; Food & Beverages; Chemicals & Materials; and Technology, Media, & Telecommunications Author’s Bio Akshay Senior Market Research Expert at Business Market Insights
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Anti-ADAR2 (480-530) ADARB1 Antibody
Anti-ADAR2 (480-530) ADARB1 Antibody Catalog number: B2020760 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 100 uL Molecular Weight or Concentration: 80.763 kDa Supplied as: Liquid Applications: a molecular tool for various biochemical applications Storage: -20°C Keywords: Double-stranded RNA-specific editase 1;3.5.4.37;RNA-editing deaminase 1;RNA-editing enzyme 1;dsRNA…
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Can We Control Genetic Inheritance? New RNA Research Opens Doors to Possibilities
Researchers at the University of Maryland uncover new pathways for double-stranded RNA (dsRNA) to enter cells, offering insights into gene regulation across generations and advancements in RNA-based drugs.
RNA-based drugs, such as the widely successful RNA vaccines and emerging double-stranded RNA (dsRNA) therapies, represent a groundbreaking approach to combating human diseases. However, a critical challenge remains: efficiently delivering these RNA molecules into cells.
A recent study published in eLife on February 4, 2025, may pave the way for revolutionary developments in RNA therapeutics. Using C. elegans (microscopic roundworms) as a model, researchers at the University of Maryland uncovered natural pathways for dsRNA to enter cells, revealing how RNA can influence gene regulation across multiple generations.
How RNA Shapes Inheritance
"Our findings challenge prior assumptions about RNA transfer," said Antony Jose, lead researcher and associate professor of cell biology and molecular genetics. "We discovered that RNA molecules can transmit specific instructions not just between cells, but also across generations, redefining our understanding of heredity."
A key player in this process is a protein called SID-1, which acts as a gatekeeper for dsRNA transmission. When the researchers removed SID-1, they observed enhanced gene expression changes in the worms, which were passed down for over 100 generations. Remarkably, these changes persisted even after SID-1 was reintroduced.
Implications for Human Medicine
"Proteins like SID-1 are found in humans and other animals," noted Jose. "By understanding its role, we could develop more targeted RNA-based treatments for diseases and potentially influence the inheritance of specific conditions."
The researchers also identified a gene called sdg-1, which regulates "jumping genes"—DNA sequences capable of moving to different chromosome locations. While these genes can introduce beneficial genetic variations, they often disrupt sequences and cause diseases. The team found that sdg-1 helps control the movement of jumping genes, maintaining genetic stability through a self-regulatory loop.
"It's like a thermostat balancing temperature," Jose explained. "The system allows some genetic 'jumping' for flexibility but prevents excessive movement that could harm the organism."
A Future of RNA-Driven Innovation
These findings provide valuable insights into how organisms regulate genes and maintain stability across generations. The study opens possibilities for innovative treatments targeting inherited diseases and improving RNA drug delivery systems.
Next, the research team plans to explore mechanisms related to dsRNA transfer, the location of SID-1, and why some genes are regulated across generations while others are not.
"We’re just beginning to scratch the surface," said Jose. "This work is the foundation for understanding how external RNA can drive heritable changes, with profound implications for the design and delivery of RNA-based therapies."
Discover the full story behind RNA-Based Drugs read the complete article on Hayadan.com.
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I know this post isn't U.S. specific, but it's a good point to remember that red imported fire ants (RIPA) Solenopsis invicta and black imported fire ants (BIPA) Solenopsis richteri are invasive species in the southern United States and play a role in suppressing native species.
HOWEVER, their prevalence as an invasive species worldwide lends itself to the incredibly prolific research done on them! RIPA, as it turns out, prefer disturbed land over undisturbed land and suppress more native species in urban/developed areas over native species in undeveloped areas.
Interestingly, they're considered pests due to their prevalence in these urban areas (and their painful stings) when they're actually beneficial to our agricultural environments by acting as an eco-'friendly' insecticide and beneficial to individuals for their pervasive hunting of ticks and other biting insects that spread disease. Their presence as pests is not invalidated though, as they pose a threat to both native vertebrae (reptiles, avians) and structural security.
We can all agree that insecticides are bad. Commercial insecticides often target organisms non-specifically, negatively affecting beneficial native wildlife as well as pest agricultural insects. Looping back to the extensive research conducted on RIVA and BIVA, a less pervasive method of invasive ant control has been proposed through the application of the SINV-1, a double stranded RNA (dsRNA) to affect target species.
[1]
All to say, it's good to remember that species don't know they're invasive. Organisms do not have a concept of evil, and are being opportunistic by nature - much of which is caused by human interference. Suchlike, elimination of invasive species is not morally "wrong" either and works to undo threats of invasive species to native wildlife! If you live in the south, I highly encourage doing research on invasive species in your area and how to identify them. Oftentimes invasive reptiles can even be kept as pets provided you have the facilities to care for them and ensure they do not have illnesses that your other herps may catch.
Also good to note that, among all the misinformation going around right now (and the. uh. socioeconomic state of the United States), ENTEMOLOGY IS A VERY IMPORTANT FIELD OF STUDY. Without it, we would not have the agricultural advantages we do now, among other important research on virus transmission.
Sorry about the huge tangent, I think knowing bugs on more than a base level lets you appreciate them more. :]
(All this to say, I work at a wildlife rehab facility and I will be blasting RIFAs off of bird feeding platforms with a hose today LMAO, ants are cool but the birds gotta eat)
they say they love insects but they hate wasps and mosquitoes

#gulf coast#gulf coast wildlife#ants#invasive species#rifa#bifa#red imported fire ant#black imported fire ant#Solenopsis invicta#Solenopsis richteri#entemology#conservation
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Reliable Panitumumab ELISA Kits from Krishgen Biosystems for Accurate Research Results
Krishgen Biosystems offers high-quality Panitumumab ELISA KITS designed for precise and reliable quantification of Panitumumab in various samples. Our ELISA kits are ideal for research applications, including pharmacokinetics and drug monitoring studies. With easy-to-follow protocols and robust performance, Krishgen Biosystems ensures that researchers get consistent, reproducible results. Each kit is carefully manufactured to meet industry standards, offering dependable solutions for your laboratory needs. Choose Krishgen Biosystems for your Panitumumab ELISA kit requirements and experience top-tier quality in your research. Achieve accurate and trustworthy results with Krishgen Biosystems today!
#dsrna antibody j2#cytokine elisa#mab-based elisa#panitumumab elisa#semaglutide elisa#roledumab elisa
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カワラタケ由来の糖タンパクであるクレスチンは
経口投与なので使用しやすいが、
レンチナンは静脈注射であり、
それを含むシイタケを食べた場合の効果は明らかでない。
レンチナンとは別の成分であるが
シイタケには微量成分として二重鎖RNA(dsRNA)が含まれている。
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Multifaceted roles of #RNA editing enzyme ADAR1 in innate immunity [Perspective]
Innate immunity must be tightly regulated to enable sensitive pathogen detection while averting autoimmunity triggered by pathogen-like host molecules. A hallmark of viral infection, double-stranded RNAs (dsRNAs) are also abundantly encoded in mammalian genomes, necessitating surveillance mechanisms to distinguish ‘self’ from ‘non-self.’ ADAR1, an RNA editing enzyme, has emerged as an essential safeguard against dsRNA-induced autoimmunity. By converting adenosines to inosines (A-to-I) in long dsRNAs, ADAR1 covalently marks endogenous dsRNAs, thereby blocking the activation of the cytoplasmic dsRNA sensor MDA5. Moreover, beyond its editing function, ADAR1 binding to dsRNA impedes the activation of innate immune sensors PKR and ZBP1. Recent landmark studies underscore the utility of silencing ADAR1 for #cancer immunotherapy, by exploiting the ADAR1-dependence developed by certain tumors to unleash an anti-tumor immune response. In this perspective, we summarize the genetic and mechanistic evidence for ADAR1’s multipronged role in suppressing dsRNA-mediated autoimmunity and explore the evolving roles of ADAR1 as an immuno-oncology target. http://rnajournal.cshlp.org/cgi/content/short/rna.079953.124v1?rss=1&utm_source=dlvr.it&utm_medium=tumblr
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RNA-interference Market Potential Growth Opportunities And Competitive Landscape Report And Forecast 2024-2033
RNA interference (RNAi) is a process in which RNA molecules are used to inhibit gene expression or silence genes. RNAi occurs naturally in plants and animals and has been harnessed as a tool for biotechnology and medicine. RNAi is triggered by the presence of double-stranded RNA (dsRNA). When dsRNA is introduced into a cell, it is processed by an enzyme called Dicer into small interfering RNA (siRNA). SiRNA consists of two strands of RNA that are complementary to each other and bind to each other to form a double-stranded molecule. SiRNA then binds to a protein called RNA-induced silencing complex (RISC), which cleaves the complementary RNA strand. This process leads to the degradation of mRNA and the inhibition of gene expression.
Key Trends
One trend is the increasing use of RNAi in vivo, in animal models of disease, and in agricultural settings. This is driven in part by the development of more effective delivery methods, such as lipid nanoparticles and viruses.
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Another trend is the increasing use of RNAi for target validation, as it provides a quick and efficient way to assess the function of a gene of interest.
Finally, the increasing use of next-generation sequencing (NGS) to generate siRNA libraries is providing a powerful tool for functional genomics studies.
Key Drivers
The key drivers of the RNA-interference market are the increasing demand for RNA-based therapeutics, the rising prevalence of chronic diseases, and the growing investment in RNA-based research.
The demand for RNA-based therapeutics is increasing due to the growing understanding of the role of RNA in disease pathogenesis.
The prevalence of chronic diseases is rising due to the aging population and the growing prevalence of lifestyle diseases. Chronic diseases are often associated with aberrant gene expression, making RNA-based therapeutics an attractive treatment option.
The investment in RNA-based research is growing due to the increasing understanding of the role of RNA in disease pathogenesis and the potential of RNA-based therapeutics.
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Research Objectives
Estimates and forecast the overall market size for the total market, across product, service type, type, end-user, and region
Detailed information and key takeaways on qualitative and quantitative trends, dynamics, business framework, competitive landscape, and company profiling
Identify factors influencing market growth and challenges, opportunities, drivers and restraints
Identify factors that could limit company participation in identified international markets to help properly calibrate market share expectations and growth rates
Trace and evaluate key development strategies like acquisitions, product launches, mergers, collaborations, business expansions, agreements, partnerships, and R&D activities
Thoroughly analyze smaller market segments strategically, focusing on their potential, individual patterns of growth, and impact on the overall market
To thoroughly outline the competitive landscape within the market, including an assessment of business and corporate strategies, aimed at monitoring and dissecting competitive advancements.
Identify the primary market participants, based on their business objectives, regional footprint, product offerings, and strategic initiatives
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Market Segments
The RNA-interference market is segmented by technology, application, and region. By technology, the market is classified into nanoparticle drugs, pulmonary drugs, and others. Based on the application, it is bifurcated into infectious disease, cardiology, and others. Region-wise, the market is segmented into North America, Europe, Asia Pacific, and the rest of the World.
Key Players
The RNA-interference market includes players such as Alnylam Pharmaceuticals Inc., Arrowhead Pharmaceuticals Inc., CureVac AG, Dicerna Pharmaceuticals Inc., Gradalis Inc., Ionis Pharmaceuticals Inc, Merck & Co. Inc., Moderna Inc., Quark Pharmaceuticals Inc, Silence Therapeutics Plc, and others.
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Scope – Highlights, Trends, Insights. Attractiveness, Forecast
Market Sizing – Product Type, End User, Offering Type, Technology, Region, Country, Others
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Business Framework – Case Studies, Regulatory Landscape, Pricing, Policies and Regulations, New Product Launches. M&As, Recent Developments
Competitive Landscape – Market Share Analysis, Market Leaders, Emerging Players, Vendor Benchmarking, Developmental Strategy Benchmarking, PESTLE Analysis, Value Chain Analysis
Company Profiles – Overview, Business Segments, Business Performance, Product Offering, Key Developmental Strategies, SWOT Analysis.
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