#factorV

[indiaivfsurrogacy-blog]

Recurrent Miscarriage https://drrichikasahayshukla.com/ It can be heartbreaking to miscarry one baby after another. Each new pregnancy brings both hope and anxiety. And each new loss may be harder to bear, especially if you feel that time is running out. The experience can place great strain on even the strongest relationships. You and your partner might react differently from each other and that can cause great tension. Family and friends may find it harder to support you with each miscarriage; they may even think you’re getting used to loss and able to cope. And all the time there may be a sense that your life is on hold while you try – and try again – for a baby. What is recurrent miscarriage? Recurrent miscarriage means having three or more miscarriages in a row. It affects about one in every hundred couples trying for a baby. Sometimes a treatable cause can be found, and sometimes not. But in either case, most couples are more likely to have a successful pregnancy next time than to miscarry again. Testing after recurrent miscarriage If you have had three miscarriages in a row, you should be offered tests to try to find the cause. This should happen whether or not you already have one or more children. Testing is not usually offered after one or two early miscarriages (up to 14 weeks) because these are often due to chance. But you might be offered tests after two early miscarriages if you are in your late 30s or 40s or if it has taken you a long time to conceive. If you had a late (second trimester) miscarriage, where your baby diedafter 14 weeks of pregnancy, you should be offered tests after this loss. Why recurrent miscarriage happens Your risk of recurrent miscarriage is higher if: you and your partner are older; the risk is highest if you are over 35 and your partner over 40; you are very overweight. Being very underweight may also increase your risk. Each new pregnancy loss increases the risk of a further miscarriage. But even after three miscarriages, most couples will have a live baby next time Known causes Antiphospholipid syndrome (APS) This blood clotting problem is the most important treatable cause of recurrent miscarriage. It happens when your immune system makes abnormal antibodies that attack fats called phospholipids in your blood. This makes the blood more ‘sticky’ and likely to clot, which is whyAPS is sometimes called ‘sticky blood syndrome’. It is also known as ‘Hughes syndrome’ after the expert who named it. It is not clear why these antibodies cause miscarriage. They may stop the pregnancy embedding properly in the uterus (womb);or they may interfere with blood flow to the placenta, which supports the baby. APS can also lead to problems in later pregnancy, including the baby not growing enough, pre-eclampsia or stillbirth. Other blood clotting problems Some inherited blood clotting disorders can cause recurrent miscarriage, particularly after 14 weeks. These include factorV Leiden, factor II (prothromobin), gene mutation and protein S deficiency Abnormal chromosomes The chromosomes in every cell of your body carry hereditary information in the form of genes. Everyone has 23 pairs of chromosomes, and 22 of these are the same in men and women. The 23rd pair are different because they determine gender. Men normally have one X and oneY chromosome and women two X chromosomes. A baby inherits half its chromosomes from each parent. About half of all miscarriages happen because the baby’s chromosomes are abnormal. This is not usually an inherited problem: it happens when the egg and sperm meet or soon after the egg is fertilised. The older you are the more likely this is to happen. Much less commonly (in less than five in one hundred couples with recurrentmiscarriage), one partner carries a chromosomal defect called a ‘balanced translocation’. This doesn’t cause a problem for the parent, but it can be passed on to the baby as an ‘unbalanced translocation’. This means that some genetic information is duplicated and some is missing. Cervical weakness (also known as ‘incompetent cervix’) Some women – probably less than one in a hundred – have a weakness in the cervix that allows it to dilate too early. This is a known cause of late (second trimester) miscarriage. Possible causes Abnormally-shaped uterus Some miscarriages, particularly late ones, are thought to happen because the uterus (womb) has an abnormal shape. It may be divided down the centre – known as ‘bicornuate’ or ‘septate’ uterus;or just one half of the terus may have developed – known as ‘unicornuate’ uterus. It is not clear from research how many women with recurrent miscarriage have these abnormalities. Also we don’t know how common these problems are in women who don’t miscarry. This makes it impossible to be sure that they cause miscarriage Polycystic ovary syndrome (PCOS) Women with this condition have many small cysts in their varies. They also tend to have hormonal problems, including high levels of insulin and male hormone in the blood. It is these problems that are thought to play a part in recurrent miscarriage, but it is not clear how. Infection Some serious infections can cause or increase the risk of single miscarriages. These include toxoplasmosis, rubella, listeria and genital infection. But it is not clear whether infection plays a role in recurrent miscarriage. Immune problems Raised levels of uterine NK (uNK) cells may increase the risk ofrecurrent miscarriage, ut more research is needed to prove this. It’s important to know that these uNK cells are different from he NK cells found in general circulating blood (e.g. from your arm). Diabetes and thyroid problems Uncontrolled diabetes and untreated thyroid problems can cause miscarriage. But well-controlled diabetes and treated thyroid problems do not cause recurrent miscarriage.

[factorvleiden]

Birth Control

Women's Health

Many popular birth control methods increase the likelihood of blood clots. Therefore those of us with Factor V Leiden have to find alternatives. It is important to consult with your doctor/gynecologist about birth control methods, but here are a few options to bring up when you go in!

Dawn Stacey M.Ed, LMHC lists the following progestrogen-only birth control methods:

Depo Provera “The Shot” - Slowly releases progestestin medroxyprogesterone acetate and prevents pregnancy for 11-14 weeks. Users typically receive 4 injections a year.

IUD -  Small, t-shaped device that is inserted into the uterus with strings hanging down through the cervix. It continually releases progestin up to 5 years. Can be removed before the 5 year limit.

Implanon/Nexplanton - Thin, flexible, and small piece of plastic that is inserted into the arm. Continually releases progestin and etonogestrel and protects against pregnancy for up to 3 years. Procedure requires anesthetic, but only takes a few minutes.

Progestin-Only Birth Control Pills “The Mini Pill” - Oral contraceptive with no estrogen. Comes in packs of 28, which must be taken every day for a continuous 4-week cycle. No placebos, all pills are active, and must be taken at the same time every day to ensure effectiveness.

[factorvleiden]

Heterozygous Vs. Homozygous

Medical

Each person has 2 copies of the The Factor V protein gene, which are inherited from both parents. To get the disorder at least one of those genes must have the Factor V Leiden mutation.

Heterozygous Factor V Leiden

The type of Factor V Leiden where you have inherited 1 mutated Factor V Leiden gene and 1 normal Factor V gene

Occurs in about 5/100 people of Caucasian decent

What does this mean for you? Above average risk of developing blood clots in your legs (DVT) and lungs (PE)

Homozygous Factor V Leiden

The type of Factor V Leiden where you've inherited 2 mutated Factor V genes (For this to occur you must have one parent that's homozygous and the other heterozygous or both homozygous)

Occurs in about 1/100 people of Caucasian decent

What does this mean for you? Greatly increased risk of developing blood clots in your legs (DVT) and lungs (PE)

Source: Stoptheclot.org

[factorvleiden]

Nutrition

Vitamin K is most commonly found in dark, green foods. It is essential for most people's coagulation of blood, AKA clotting.

However, people who have Factor V Leiden already have increased blood coagulation, and extra clotting can lead to serious health risks. Vitamin K intake should be monitored and limited, but not necessarily cut out of one's diet. It is also important for healthy bones, and can potentially decrease the risk for Alzheimer’s, cancer, and heart disease. If you have Factor V Leiden it is recommended that you limit your intake of foods high in vitamin K and keep the amount consistent from day-to-day.

According to HealthAliciousNess the top 10 foods with Vitamin K are:

1. Herbs: Basil, Sage, and Thyme (1715μg per 100g serving)

2. Dark Leafy Greens: Kale (882μg/100g) and Collards, Cress, Spinach Turnip/Mustard Greens, Swiss Chard, and dark green Lettuce (62.5μg/100g)

3. Spring Onions aka Scallions (207μg/100g)

4. Brussels Sprouts (194μg/100g)

5. Broccoli (141μg/100g)

6. Chili Powder (106μg/100g)

7. Asparagus (80μg/100g)

8. Cabbage (76μg/100g)

9. Pickled Cucumber (77μg/100g)

10. Prunes (60μg/100g)

Some other foods with Vitamin K:

Sun-Dried Tomatoes

Okra

Soybean Oil

Carrots

Celery

Edamame

Dry Roasted Cashews

Fruit: Blackberries, Blueberries, Mulberries, Raspberries, Figs, and Pears

Herbs: Parsley, Coriander, Marjoram, Oregano, and Basil

Spices: Curry Powder, Paprika, and Cayenne

Onions

Peas

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For those on the drug Warfarin (which is used as a blood thinner) it is recommended that they monitor Vitamin K by:

Eating no more than 1 serving of food 160μg+ a day (Broccoli, dark greens, brussel sprouts, scallions, green herbs)

Eating no more than 3 servings of of foods 45μg-160μg a day (Asparagus, cabbage, cucumbers, prunes, okra, ect...)

Keeping their intake similar day-to-day

*These numbers are for those taking Warfarin, but can still help guide dietary needs for unmedicated people with Factor V Leiden and other blood clotting disorders. Consult with your doctor or hematologist if you have any further questions!

For more information, visit: LIVESTRONG and HealthAliciousNees

[nekomimikyuuu]

So excite!

I got a call yesterday from the rheumatologist. Turns out they got a cancelation and called me first so instead of having to wait till June to get this ball rolling I go in today! So nervous. So much blood to be drawn. Not a happy time for my asshole veins.