#mtor

[medicomunicare]

Finding the Tau of leukemia: the TAUTological focusing on glucose metabolism was not foreseen

A new scientific study identified taurine, which is made naturally in the body and consumed through some foods, as a key regulator of myeloid cancers such as leukemia, according to a paper published in the journal Nature. The Wilmot Cancer Institute investigators at the University of Rochester were able to block the growth of leukemia in mouse models and in human leukemia cell samples by…

[menopaused]

mTOR inhibition improves immune function in the elderly

[hardoctornews]

Obesità e tumore al seno: quale relazione?

Numerose ricerche scientifiche hanno ormai stabilito una stretta correlazione tra obesità e aumento del rischio di sviluppare il diabete mellito di tipo 2 (DMT2). Questo legame si basa sull’effetto dell’eccesso di peso nell’indurre l’insulina-resistenza, nell’elevare i livelli di estrogeni nel sangue attraverso l’up-regolazione dell’enzima aromatasi, e nella confezione del rilascio di specie…

[noname21sstuff-blog]

Al Habtoor Motors and JAC Motors are bringing incredible deals to all with the JAC S3+

The JAC S3+ combines both practicality and style to create the perfect urban crossover in a mid-range size.

The JAC S3+ combines both practicality and style to create the perfect urban crossover in a mid-range size. Al Habtoor Motors, the exclusive distributor of JAC Motors in the UAE, is offering unbeatable deals on the JAC S3+. With excellent servicing and other customer benefits, Al Habtoor Motors encourages all to take advantage of this deal before it ends by the end of September. Prioritising…

[bpod-bpod]

Mushroom for Improvement

Burrowing into the brains of young caterpillars, Cordyceps militaris is a fungus with control in mind. Yet it also produces a “promising” natural chemical, cordycepin, shown to kill certain human cancer cells. Promising chemicals aren’t always practical or free from side effects, though, so establishing the underlying details is essential to their success in treating patients. Although Cordyceps has had a place in Chinese medicine for over 1500 years, cordycepin was first extracted from a bubbling mushroom broth in 1950. The intervening decades have revealed details carefully – challenged by the compound’s fast metabolism; cordycepin breaks down quickly inside living cells. Now, delving deeper into how cordycepin kills cells, scientists find exciting molecular clues: cordycepin is able to block growth factors that might otherwise help cancers grow, by guiding a set of intracellular signals known as mTOR. This information will be vital to fulfilling on the Cordyceps’ promise.

Written by John Ankers

Image by Holger Krisp from Wikimedia Commons

Research from the School of Pharmacy, Biodiscovery Institute, University of Nottingham, UK

Image originally published with a Creative Commons Attribution CC-BY-3.0

Research published in FEBS Letters, November 2024

You can also follow BPoD on Instagram, Twitter and Facebook

[kingme1002]

RADICAL LIFE EXTENSION:

### Key Areas of Research and Approaches:

1. **Genetic Engineering**:

- **CRISPR and Gene Editing**: Technologies like CRISPR-Cas9 allow scientists to modify genes associated with aging and age-related diseases. By editing or repairing genes, it may be possible to slow down or reverse aging processes.

- **Telomere Extension**: Telomeres are protective caps at the ends of chromosomes that shorten with age. Research is exploring ways to extend or maintain telomere length to delay cellular aging.

2. **Senescence and Cellular Repair**:

- **Senolytics**: These are drugs designed to selectively eliminate senescent cells, which accumulate with age and contribute to tissue dysfunction and chronic diseases. Removing these cells can improve health and extend lifespan.

- **Stem Cell Therapy**: Stem cells have the potential to regenerate damaged tissues and organs. Research is ongoing to harness stem cells for repairing age-related damage and restoring function.

3. **Metabolic and Dietary Interventions**:

- **Caloric Restriction**: Studies have shown that reducing calorie intake without malnutrition can extend lifespan in various organisms. Researchers are investigating the mechanisms behind this and developing drugs that mimic the effects of caloric restriction.

- **Rapamycin and mTOR Inhibition**: Rapamycin, a drug that inhibits the mTOR pathway, has been shown to extend lifespan in animal models. It is being studied for its potential to delay aging in humans.

4. **Regenerative Medicine**:

- **Tissue Engineering**: Creating replacement tissues and organs using bioengineering techniques can address age-related degeneration and organ failure.

- **3D Bioprinting**: This technology allows for the creation of complex tissues and organs layer by layer, potentially providing replacements for damaged or aging body parts.

5. **Artificial Intelligence and Biotechnology**:

- **AI in Drug Discovery**: AI is being used to accelerate the discovery of new drugs and therapies for aging-related conditions.

- **Biomarkers of Aging**: Developing accurate biomarkers to measure biological age and the effectiveness of anti-aging interventions.

6. **Cryonics and Mind Uploading**:

- **Cryonics**: The practice of preserving bodies or brains at extremely low temperatures with the hope that future technology can revive and rejuvenate them.

- **Mind Uploading**: A speculative concept where a person's consciousness is transferred to a digital substrate, potentially allowing for indefinite existence in a virtual environment.

### Ethical and Societal Considerations:

- **Equity and Access**: Ensuring that life-extending technologies are accessible to all, not just the wealthy.

- **Overpopulation**: Addressing the potential impact on global population and resources.

- **Quality of Life**: Ensuring that extended life is accompanied by improved health and well-being, not just prolonged existence.

### Current Status:

While significant progress has been made in understanding the biology of aging, most radical life extension technologies are still in the experimental stages. Human trials are ongoing for some interventions, but widespread application is likely still years or decades away.

Radical life extension remains a highly interdisciplinary field, combining insights from genetics, biotechnology, medicine, and computational science. The ultimate goal is to not only extend human lifespan but to ensure that those additional years are lived in good health and vitality.

[medicomunicare]

Omega-6 amici del tumore mammario: ecco come fa l'acido linoleico a stimolare la crescita

L’acido linoleico (polinsaturo omega-6) è un nutriente derivato dalla dieta che è considerato essenziale nei mammiferi per supportare molteplici processi corporei. Tuttavia, l’abbondanza di questo grasso nella dieta “occidentale” è aumentata in modo significativo dagli anni ’50, in concomitanza con il maggiore utilizzo di oli di semi in cibi fritti e ultra-lavorati. Ciò ha portato a…

[imanopossum]

went to a presentation cause i was selected to be on the council of hiring a new biochem faculty and he mentioned dna plasmids in bacteria (and how it relates to beta helicase and its connection to ATR and mTOR kinases cause that’s what his PhD thesis research is on) and remembered i genetically engineered e. coli to be bioluminescent using plasmids a few years ago so here yall go

[ronniesfinalproject]

i jsit realdized its lisk. seven freaking thiirtyb for you. tahdt is crazy ive been up all night im not like up super earldy i just maje bad desicions and do mtor taken care of myself

pls get some aleep tonight king you deserve ut 🫶🫶

[darkmaga-returns]

A major peer-reviewed study has confirmed that the spike protein from Covid mRNA “vaccines” is a rogue operator that infests every cell in the body to rewire human biology, causing deadly cancers, brain disorders, immune system failure, and death.

The alarming findings reveal that the spike protein operates independently from the mRNA shot to hijack human cellular machinery in unexpected ways.

The bombshell study was led by Dr. Giovanni Colonna of the Unit of Medical Informatics at the University of Campania.

The results of the study were published in the leading medical journal Biomolecules.

According to the study, the S1 subunit of the spike protein produced after mRNA injection can operate independently from the rest of the “vaccine.”

Once it enters the body, it continues to spread to every organ, hijacking human cells.

By mapping thousands of experimentally validated protein interactions, Colonna shows that S1 alone may trigger over 2,500 biological processes.

This is more than 40% above its activity when operating as part of the whole viral complex.

Among the most disturbing findings of the study is that S1 directly engages with proteins involved in cancer-related pathways such as mTOR and PI3K.

[armani-customs]

Maputo - Wikipedia

Water-Air with Earth Stars

Cancer Virgo-Libra (Water Warrior Aristocracy)

Cancer Leo Gemini (Water Sun God); Zodiac Sign Obasi Luminary (ASE and ASE Lunar)

Cancer Uranus Saturn (Obasi Conjunction)

Dolphins Spirit Animal with Swan-Eagle Wings

Potamides Urdines 

Shiva Lessons: Angel Equivalent Celestial Deities, Sky Sun-Water God, Warrior Aristocracy, Meditation Yogi; Therapies include herbal medicines, special diets, meditation, yoga, massage, laxatives, enemas, and medical oils; Indian Methods with Jamaican Ingredients Fusion Food (Insulin Sensitivity Anabolic Metabolism Fighters Diet: Leucine (mTOR); Sweet Potatoes, Omega 3; Mollusk and Decapoda, and Iron; Onions-Mushroom-Spinach and Strawberry Dessert); Slum Freedom for Deities

Water Deities Solar Deities Sky Deities Solar Monotheism Goetia Religion SOLAÍ SAÕ; God: SOXAÍ (Sun)

Sun worship, veneration of the sun or a representation of the sun as a deity, as in Atonism in Egypt in the 14th century BCE. Although sun worship has been used frequently as a term for “pagan” religion, it is, in fact, relatively rare. Though almost every culture uses solar motifs, only a relatively few cultures (Egyptian, Indo-European, and Meso-American) developed solar religions. All of these groups had in common a well-developed urban civilization with a strong ideology of sacred kingship. In all of them the imagery of the sun as the ruler of both the upper and the lower worlds that he majestically visits on his daily round is prominent. These qualities—sovereignty, power of beneficence, justice, and wisdom—are central to any elite religious group, and it is within these contexts that a highly developed solar ideology is found. Kings ruled by the power of the sun and claimed descent from the sun. Solar deities, gods personifying the sun, are sovereign and all-seeing. The sun is often a prime attribute of or is identified with the Supreme Deity. 

There are many different and distinct types of religious waters: holy, sacred, neutral, and even evil. The ways various divinities invest waters with specific qualities and capacities depend upon a wide range of ecological, theological, and eschatological factors; some are shaped by the environment while others are purely ontological and concerned with otherworldly realms, and often there is an intimate relation between the mundane and the divine. Rivers, rain, lakes, springs, and waterfalls are some specific forms of religious water, which also relate to seasonality and changing hydrological cycles. All these variations create different dependencies not only to ecological factors but more importantly to divine actors. Religious water may heal and bless individuals and be a communal source for fertility and plentiful harvests, but may also work as a penalty, wreaking havoc on society as floods or the absence of the life-giving rains in agricultural communities. Given the great variation of religious waters throughout history where even the same water may attain different qualities and divine embodiments, divine waters define structuring practices and principles in ecology and cosmology.

Philosophy

the study of the fundamental nature of knowledge, reality, and existence, especially when considered as an academic discipline.

a particular system of philosophical thought.

plural noun: philosophies

"Schopenhauer’s philosophy"

the study of the theoretical basis of a particular branch of knowledge or experience.

"the philosophy of science”

Senate of Escudo Saõ as Topic and Things to Write about:

A senate is a deliberative assembly, often the upper house or chamber of a bicameral legislature.

Escudo is Religious Pendant; Flag; and Crista

Quasi Trade System is Mediterranean Sea (Black Sea; Red Sea Basins and Channels)

Quasi Culture Exchange with Indian Ocean Trade involves the exchange of goods and services between individuals, groups, or regions. Cultural exchange encompasses the sharing of ideas, beliefs, customs, and technologies across societies. Trade routes are established pathways along which goods and people move (Silk Roads, Indian Ocean trade)

Quasi Economy: Blue economy is a term in economics relating to the exploitation, preservation and regeneration of the marine environment. Its scope of interpretation varies among organizations. However, the term is generally used in the scope of international development when describing a sustainable development approach to coastal resources and ocean development. This can include a wide range of economic sectors, from the more conventional fisheries, aquaculture, maritime transport, coastal, marine and maritime tourism,[1] or other traditional uses, to more emergent activities such as coastal renewable energy, marine ecosystem services (i.e. blue carbon), seabed mining, and bioprospecting.

Political Economy with Religious Politics quasi-religions are non-religious movements which have unintended similarities to religions, such as political movements.

A federation (also called a federal state) is an entity characterized by a union of partially self-governing provinces, states, or other regions under a federal government (federalism). Observer status is a privilege granted by some organizations to non-members to give them an ability to participate in the organization's activities. Observer status is often granted by intergovernmental organizations (IGO) to non-member parties and international nongovernmental organizations (INGO) that have an interest in the IGO's activities. Observers generally have a limited ability to participate in the IGO, lacking the ability to vote or propose resolutions. Indigenous Peoples are distinct social and cultural groups that share collective ancestral ties to the lands and natural resources where they live, occupy or from which they have been displaced. The land and natural resources on which they depend are inextricably linked to their identities, cultures, livelihoods, as well as their physical and spiritual well-being. They often subscribe to their customary leaders and organizations for representation that are distinct or separate from those of the mainstream society or culture. Many Indigenous Peoples still maintain a language distinct from the official language or languages of the country or region in which they reside; however, many have also lost their languages or on the precipice of extinction due to eviction from their lands and/or relocation to other territories, and in.

Linguistic Minorities are group or collectivises of individuals residing in the territory of India or any part thereof having a distinct language or script of their own. Fundamental criteria for belonging to a language minority are (1) self-categorization, (2) common ancestry, (3) distinctive linguistic, cultural, or historical traits, and (4) a form of social organization that places the language group in a minority position. Aristocrats, or the ruling elites, tend to enjoy both social and economic prestige as well as political power. They usually have a specific honorary title, such as Duke, Duchess, Baron, Baroness, etc. In addition, children usually inherit aristocratic status from their parents. Feudalism, also known as the feudal system, was a combination of legal, economic, military, cultural, and political customs that flourished in medieval Europe from the 9th to 15th centuries. The aristocracy[1] is historically associated with a "hereditary" or a "ruling" social class. In many states, the aristocracy included the upper class of people (aristocrats) with hereditary rank and titles.[2] In some, such as ancient Greece, ancient Rome, or India, aristocratic status came from belonging to a military class. It has also been common, notably in African and Oriental societies, for aristocrats to belong to priestly dynasties. Aristocratic status can involve feudal or legal privileges.[3] They are usually below only the monarch of a country or nation in its social hierarchy.[4]

The philosopher king is a hypothetical ruler in whom political skill is combined with philosophical knowledge. The concept of a city-state ruled by philosophers is first explored in Plato's Republic, written around 375 BC. Stoicism is a school of Hellenistic philosophy that flourished in Ancient Greece and Ancient Rome.[1] The Stoics believed that the practice of virtue is enough to achieve eudaimonia: a well-lived life. The Stoics identified the path to achieving it with a life spent practicing the four cardinal virtues in everyday life — prudence, fortitude, temperance, and justice — as well as living in accordance with nature. It was founded in the ancient Agora of Athens by Zeno of Citium around 300 BCE.

Warrior Aristocracy (quasi-military organisation has more near-identical to military aspects (i.e., militia, political party, guerrilla, rebel, organized crime, etc.) A navy, naval force, military maritime fleet, war navy, or maritime force is the branch of a nation's armed forces principally designated for naval and amphibious warfare; namely, lake-borne, riverine, littoral, or ocean-borne combat operations and related functions. It includes anything conducted by surface ships, amphibious ships, submarines, and seaborne aviation, as well as ancillary support, communications, training, and other fields. The strategic offensive role of a navy is projection of force into areas beyond a country's shores (for example, to protect sea-lanes, deter or confront piracy, ferry troops, or attack other navies, ports, or shore installations). The strategic defensive purpose of a navy is to frustrate seaborne projection-of-force by enemies. The strategic task of a navy also may incorporate nuclear deterrence by use of submarine-launched ballistic missiles. Naval operations can be broadly divided between riverine and littoral applications (brown-water navy), open-ocean applications (blue-water navy), and something in between (green-water navy), although these distinctions are more about strategic scope than tactical or operational division. The definition of a proto-state is not concise, and has been confused by the interchangeable use of the terms state, country, and nation to describe a given territory.[29] The term proto-state is preferred to "proto-nation" in an academic context, however, since some authorities also use nation to denote a social, ethnic, or cultural group capable of forming its own state.[29] A proto-state does not meet the four essential criteria for statehood as elaborated upon in the declarative theory of statehood of the 1933 Montevideo Convention: a permanent population, a defined territory, a government with its own institutions, and the capacity to enter into relations with other states.[29]

Transnational Capitalist Class

Monopoly Class

Ruling Class

Arithmetic Trades Class

Woven Fabric/Subsistence Farming and Fishing/Metallurgy/Rice Polyculture Indigenous Class

Life Cycle Engineering as Topic and Things to Write about:

Life-cycle engineering (LCE) is a sustainability-oriented engineering methodology that takes into account the comprehensive technical, environmental, and economic impacts of decisions within the product life cycle. Alternatively, it can be defined as "sustainability-oriented product development activities within the scope of one to several product life cycles."[1] LCE requires analysis to quantify sustainability, setting appropriate targets for environmental impact. The application of complementary methodologies and technologies enables engineers to apply LCE to fulfill environmental objectives.

Economics as Topic and Things to Write about:

Life-Cycle Hypothesis (LCH) The life-cycle hypothesis (LCH) is an economic theory that describes the spending and saving habits of people over the course of a lifetime. The theory states that individuals seek to smooth consumption throughout their lifetime by borrowing when their income is low and saving when their income is high.

Behavioral economics is the study of psychology as it relates to the economic decision-making processes of individuals and institutions. Rational behavior is the cornerstone of rational choice theory, a theory of economics that assumes that individuals always make decisions that provide them with the highest amount of personal utility. These decisions provide people with the greatest benefit or satisfaction given the choices available.

Philosopher Kgosi & Warrior Aristocracy Of Saõ as Topic and Things to Write about:

This Antiquity cultural foundation has been immensely influential on the language, politics, law, educational systems, philosophy, science, warfare, literature, historiography, ethics, rhetoric, art and architecture of both the Western, and through it, the modern world. Respect for the ancient people of Greece and Rome affected politics, philosophy, sculpture, literature, theatre, education, architecture, and sexuality.

Cipher Igbo Language

Cultivator Political Science with Maritime Diplomacy for Distribution of Resources and Status Politics

Interpol and Naval Martial Law

Socio-economic status Education

Obasian Philosophy Political Skill is Combined with Philosophical Knowledge; Immoral Acts for Political Glory. Antiquity are Plato and Machiavelli.

Life and Social Sciences

Naval, Raiding, and Siege Warfare

Scientific Objective and Decadence Literature

Sao Civilization Historiography

Warrior Stoicism Ethics

Syncdocu Argot Rhetoric

Harmony and Contrast Painting with Drum Duet

Beaux Arts Architecture

Herbs to Synthetic and Designer Pharmaceuticals

Dolphins as Pack Mentality

Raw Materials, Minerals, Clay-Soil River Bank Agriculture, and Aquaculture Civilization

Solaí BioAesthetics as Topic and Things to Write about:

Hyaluronic Acid Illite Pheomelanin Mid Brown Diamond Face

Grey Eyes with Blonde Hair

Hazel Eyes with Red Hair

Insulin Sensitivity with Anabolic Metabolism

Ambidextrous Hand Eye Foot Coordination

Posterior Gross Motor Skills

Savant Sensory Overload

Sensory Modulits CNS

Omega 3 6 9, Conscientiousness, and Executive Functioning Skills no Amygdala Grey Brain

GABA NMDA Receptors Sensitivity

Palace Structure (Fish Village in a Waterfront Metropolis) as Topic and Things to Write about:

Berry and Citrus Tree Gardners

Tobacco Plantation

Deliriants Fields

Drummer

Kickboxing Triangle Choke Guard Trainers

Chef Yogi Therapist

C-Suite Caretakers

Stylist; Barber; Nose

Cleaning Staff and Dry Cleaners

Potential Psychotherapist

Masculinity Psychotherapist

Organic farming is a cultivation system that prioritizes healthy food, soil, plants, and the environment by avoiding synthetic substances and chemicals. Organic farmers use natural interventions and biological fertilizers to improve soil quality and promote healthy crop growth.

In cryptography, a cipher (or cypher) is an algorithm for performing encryption or decryption—a series of well-defined steps that can be followed as a procedure. An alternative, less common term is encipherment. To encipher or encode is to convert information into cipher or code. In common parlance, "cipher" is synonymous with "code", as they are both a set of steps that encrypt a message; however, the concepts are distinct in cryptography, especially classical cryptography. The Pan-Nigerian alphabet is a set of 33 Latin letters standardised by the National Language Centre of Nigeria in the 1980s. It is intended to be sufficient to write all the languages of Nigeria without using digraphs.[1] History Several hundred different languages are spoken in Nigeria. The different Latin alphabets made it impractical to create Nigerian typewriters. In the 1980s the National Language Centre (NLC) undertook to develop a single alphabet suitable for writing all the languages of the country, and replacing use of Arabic script, taking as its starting point a model proposed by linguist Kay Williamson in 1981.[citation needed] A typeface was developed in 1985–1986 by Edward Oguejofor and Victor Manfredi, in co-operation with the NLC, with technical assistance from Hermann Zapf. The Chadic languages form a branch of the Afroasiatic language family. They are spoken in parts of the Sahel. They include 196 languages[1] spoken across northern Nigeria, southern Niger, southern Chad, and northern Cameroon. By far the most widely spoken Chadic language is Hausa, a lingua franca of much of inland Eastern West Africa, particularly Niger and the northern half of Nigeria. Hausa, along with Mafa and Karai Karai, are the only three Chadic languages with more than 1 million speakers. Igbo (English: /ˈiːboʊ/ EE-boh,[5] US also /ˈɪɡboʊ/ I-gboh;[6][7] Standard Igbo: Ásụ̀sụ́ Ìgbò [ásʊ̀sʊ̀ ìɡ͡bò] ⓘ) is the principal native language cluster of the Igbo people, an ethnicity in the Southeastern part of Nigeria.

Political Religions as Topic and Things to Write about:

Ethics*

Values*

Symbols*

Myths^

Rituals^

Archetypes*

National Liturgical Calendar^

Religious Territory*

Maritime Climate Political Science*

Import Internationalist or Export Nationalist^

Water Sun Goetia Birth (Cancer through Leo Constellation) for Calabar (also referred to as Callabar, Calabari, Calbari, Cali and Kalabar)[3] is the capital city of Cross River State, Nigeria.^

Sociological, political, and economic lens of how public policy, the political situation, and political institutions impact a country's economic standing and future.*

Port, Rivers, and Drainage Basin System Employment for Working Class^

^ Experience and * Knowledge

Ocean Economic Geography as Topic and Things to write about:

Ocean Economy*

Mineral Ocean*

Savagery Primitive Anthropology*

Port Authoritative Regime*

Aquatic Mineral Soil*

Decapod and Mollusk Farms*

Drainage Basin and Rivers*

Aquatic Science*

Waterfront Development*

Aquaculture (less commonly spelled aquiculture[1]), also known as aquafarming, is the controlled cultivation ("farming") of aquatic organisms such as fish, crustaceans, mollusks, algae and other organisms of value such as aquatic plants (e.g. lotus).*

Fishing Village*

Interconnecting Seaport*

Raves, Ocean View Vacation Homes, and Aquatic Fragrances^

Warrior Aristocracy: Port Diplomacy Royal Naval with Kickboxing^

Consumption of Collagen Mineral Water^

Mineral H²O Economy G7^

Port Diplomacy^

^ Experience and * Knowledge

African Currency as Topic and Things to Write about:

Franc Basket as Destabilizer*

Mining Unions within African Union*

Agricultural Pegged Currency*

Mining Regions*

Currency Pair as Trade Agreement Catalyst*

Homestead and Factory Line*

G20 Currency Basket^

G20 FX Counter Trading Party^

Commodity Union Ocean Economic Currency^

President Farmer/Military Naval^

OT Nexus: Intermodal freight transport involves the transportation of freight in an intermodal container or vehicle, using multiple modes of transportation (e.g., rail, ship, aircraft, and truck), without any handling of the freight itself when changing modes. The method reduces cargo handling, and so improves security, reduces damage and loss, and allows freight to be transported faster. Reduced costs over road trucking is the key benefit for inter-continental use. This may be offset by reduced timings for road transport over shorter distances. In the United Kingdom, the county lines drug supply model is the practice of trafficking drugs into rural areas and smaller towns, away from major cities. An account used by a law firm or real estate agent to control funds set aside for costs associated with a real estate transaction. This account also holds any other money put forth by the buyer and seller before the closing. A trade show, also known as trade fair, trade exhibition, or trade exposition, is an exhibition organized so that companies in a specific industry can showcase and demonstrate their latest products and services, meet with industry partners and customers, study activities of competitors, and examine recent market trends and opportunities.*

^ Experience and * Knowledge

Angel Equivalent Drumming Orchestra Development as Topic and Things to Write about:

Chieftaincy Application^

Anthropology Crista Application*

Clan Development within National Tribe^

Ethnic Separatism and Black Separatism*

Left Hand Path Divination System^

Traditional Invocation^

Invocation Psychology*

Goetia Author*

Necromancer Advisor*

Planetary Intelligence Natal Charts*

Astral Body^

Heavenly Realm^

Religions of Choice*

Spiritual Animals (Winged and Jungle Cat)^

Ceremonial Drums with Spirit and Technology*

Yogi Meditation Warrior Pose//Kickboxing Crista^

Iron K2 (Iron Calcium) as Divinity BioMetals*

Lust High and Deliriants Divination Ecstasy^

1 Year Residency for Caribbean Spiritual Development^

Shiva Lessons: Angel Equivalent Celestial Deities, Sky Sun-Water Underworld God, Warrior Aristocracy, Meditation Yogi; Therapies include herbal medicines, special diets, meditation, yoga, massage, laxatives, enemas, and medical oils; Indian Methods with Jamaican Ingredients Fusion Food (Insulin Sensitivity Anabolic Metabolism Fighters Diet: Leucine (mTOR); Sweet Potatoes, Omega 3; Mollusk and Decapoda, and Iron; Onions-Mushroom-Spinach and Strawberry Dessert)

^ Experience and * Knowledge

OBASÍ MYR. CABRAL

[2newbeginnings]

🧬 التغذية، طول العمر، والأمراض:

🎯 الفكرة الرئيسية: ما نأكله، ومتى نأكله، وكيف نحد منه، يمكن أن يؤثر مباشرة على الشيخوخة والأمراض المزمنة.

1. 🧬 كيف تؤثر التغذية على الجسم؟

✂️ إشارات النمو:

IGF‑1 (عامل يشبه الإنسولين - يحفّز النمو)

mTOR (بروتين يتحكم في انقسام الخلايا ونموها)

AMPK (مستشعر لحالة الطاقة في الخلية)

SIRT (مجموعة بروتينات تساعد في إصلاح الخلايا)

🔁 التوازن بين هذه الإشارات يحدد ما إذا كانت الخلايا ستنمو أو تصلح نفسها.

مثال مبسط:

عندما نأكل كثيرًا، IGF‑1 وmTOR يرتفعان = نمو وتسريع الشيخوخة.

وعندما نصوم أو نأكل أقل، AMPK وSIRT ينشطان = إصلاح وتجديد.

2. 🍽️ أنماط الأكل وتأثيرها

✅ التقييد الحراري (Caloric Restriction): تقليل السعرات اليومية مع الحفاظ على العناصر الغذائية المهمة

✨️ ↓ IGF‑1 وmTOR

✨️ ↑ الأوتوفاجي (عملية طبيعية تنظف الخلايا من الأجزاء التالفة)

✨️إبطاء الشيخوخة

✅ الصيام الدوري (مثل صيام 16:8 أو 5:2):

الصيام لفترات محددة يوميًا أو أسبوعيًا

→ ↑ إصلاح الخلايا، ↓ سكر الدم، ↓ الالتهاب

✅ (نظام غذائي يقلد الصيام) FMD:

أكل كمية قليلة جدًا من السعرات والدهون والبروتينات لمدة 4–5 أيام

✨️ الجسم "يعتقد" أنه في حالة صيام

✨️ ↑ تجديد الخلايا الجذعية، ↓ عوامل الشيخوخة

✨️ سهل التطبيق مقارنة بالصيام الكامل

3. 🧠 التأثيرات على الأمراض المزمنة

🍬 السكري النوع الثاني:

↓ مقاومة الإنسولين (الخلية تصبح أكثر استجابة له)

↑ التحكم في مستويات السكر

🫀 أمراض القلب:

↓ الكوليسترول الضار (LDL)

↓ ضغط الدم والالتهاب

🎗️ السرطان:

↓ IGF‑1 = ↓ إشارات تحفيز الأورام

↑ مقاومة الخلية ضد التحوّل السرطاني

🧠 الزهايمر وأمراض الدماغ:

↑ تجديد الخلايا العصبية

↓ تراكم البروتينات المرتبطة بالتدهور العصبي

4. 🥗 توصيات “نظام طول العمر” (Longevity Diet)

🔹 بروتين منخفض إلى معتدل (خاصة من مصادر نباتية) (لأن البروتين الزائد يرفع IGF‑1 ويسرّع الشيخوخة)

🔹 كربوهيدرات معقّدة (حبوب كاملة، خضروات) (للحفاظ على طاقة مستقرّة)

🔹 دهون صحية (زيت زيتون، مكسرات، أفوكادو) (لصحة القلب وتقليل الالتهاب)

🔹 صيام يومي 12 ساعة (لمنح الجسم وقتًا للإصلاح)

🔹 تكرار FMD كل شهرين إلى ثلاثة (لإعادة تهيئة الجسم وتجديد الخلايا)

5. 📌 ما الفائدة؟

✨ الأنظمة التي تحفّز الضغط الخفيف (مثل الصيام) تُنشط إصلاح الخلايا

🧹 تفعيل “الأوتوفاجي” يزيل الخلايا التالفة

🧬 ↓ الإشارات المسرّعة للشيخوخة = ↑ طول عمر صحي

✅ الخلاصة:

🧠 التغذية ليست فقط وقودًا… بل إشارة تحكم داخل الجسم

🕰️ أنماط الأكل الذكية يمكن أن تطيل الح��اة وتؤخر ظهور الأمراض

المصدر: Nutrition, longevity and disease: From molecular mechanisms to interventions: Cell

[medicomunicare]

SAMTOR: the aminoacid naviGATOR making TORC to help cancer cells for their unMET requirements

The mTOR complex (mTORC1) regulates cell growth and metabolism in response to multiple environmental signals. Nutrients signal via Rag proteins (GTPases) to promote the localization of mTORC1 to the lysosomal surface, its activation site. The mTOR1 complex is composed of more than a dozen a subunits and its complexity appears to increase over time. It has sensors for most aminoacids, especially…

[weightloss-hub]

Protein Supplements: Specifications Breakdown, FAQs, and More

Building muscle and optimizing recovery requires more than just hitting the gym consistently. Proper nutrition, particularly adequate protein intake, plays a crucial role in achieving your fitness goals. For many athletes, bodybuilders, and fitness enthusiasts, protein supplements have become an essential tool for meeting their daily protein requirements and maximizing their training results.

This comprehensive guide explores everything you need to know about protein supplements for muscle growth and recovery. From understanding different protein types and their specifications to choosing the right supplement for your specific needs, we’ll cover all aspects of sports nutrition protein supplementation to help you make informed decisions about your fitness journey.

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Understanding Protein Supplements: The Foundation of Sports Nutrition

Protein supplements serve as concentrated sources of high-quality protein designed to support muscle protein synthesis, recovery, and overall athletic performance. These supplements provide essential amino acids that your body needs to repair muscle tissue damaged during intense training sessions and build new muscle fibers for increased strength and size.

The human body requires all nine essential amino acids to effectively synthesize new proteins. Complete protein sources contain all essential amino acids in optimal ratios, making them ideal for muscle building and recovery. Most high-quality protein supplements are formulated to provide complete amino acid profiles, ensuring your muscles receive everything they need for optimal growth and repair.

Modern protein supplements offer convenience, portability, and precise dosing that whole food proteins sometimes cannot match. Whether you’re traveling, training multiple times per day, or simply struggling to meet your protein targets through food alone, supplements provide a practical solution for maintaining consistent protein intake.

Sports Nutrition Specifications: Detailed Breakdown

Protein Content and Quality Metrics

The most critical specification for any protein supplement is its protein content per serving, typically measured in grams. High-quality protein powders contain 20–30 grams of protein per serving, with premium products reaching up to 40 grams per scoop. However, protein quantity alone doesn’t determine effectiveness; the biological value and amino acid profile are equally important.

Protein Digestibility Corrected Amino Acid Score (PDCAAS) measures protein quality on a scale from 0 to 1, with higher scores indicating better amino acid profiles and digestibility. Top-tier protein supplements achieve PDCAAS scores of 1.0, indicating complete amino acid profiles that closely match human requirements. Whey protein isolate, casein, and egg protein typically achieve perfect PDCAAS scores.

Biological Value (BV) represents how efficiently your body can utilize consumed protein for muscle building and repair. Whey protein boasts the highest BV at approximately 104, followed by egg protein at 100, and casein at 77. These metrics help determine which protein sources provide the most effective muscle-building potential per gram consumed.

Amino Acid Profiles and Leucine Content

Essential amino acids, particularly branched-chain amino acids (BCAAs), play crucial roles in muscle protein synthesis. Leucine, the most anabolic BCAA, triggers the mTOR pathway responsible for initiating muscle building processes. Effective protein supplements contain 2.5–3.5 grams of leucine per serving to optimize muscle protein synthesis.

Complete amino acid profiles should include all nine essential amino acids: histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine. Premium protein supplements provide detailed amino acid breakdowns, allowing users to verify they’re receiving optimal ratios for muscle building and recovery.

Non-essential amino acids like glutamine, arginine, and glycine, while not strictly required from dietary sources, can enhance recovery, immune function, and performance when included in protein supplements. Many sports nutrition formulas include these amino acids to provide comprehensive muscle support beyond basic protein requirements.

Absorption Rates and Digestion Speed

Different protein sources exhibit varying absorption rates, affecting their optimal timing for consumption. Fast-absorbing proteins like whey protein isolate reach peak blood amino acid levels within 60–90 minutes post-consumption, making them ideal for post-workout recovery when muscles are primed for protein synthesis.

Medium-digesting proteins such as whole milk protein or whey protein concentrate provide sustained amino acid release over 2–4 hours, suitable for between-meal supplementation or pre-workout nutrition. These proteins help maintain positive nitrogen balance throughout extended periods without food intake.

Slow-digesting proteins like casein or milk protein isolate can provide amino acids for 6–8 hours, making them excellent choices for nighttime consumption. During sleep, when no food is consumed for 7–9 hours, slow-release proteins help prevent muscle breakdown and support overnight recovery processes.

Purity and Processing Specifications

Protein purity indicates the percentage of total weight comprised of actual protein versus fillers, flavoring, and other ingredients. High-quality protein supplements typically contain 80–95% protein by weight, with isolate forms achieving the highest purity levels. Premium whey protein isolates can reach 90–95% protein purity through advanced filtration processes.

Processing methods significantly impact protein quality and functionality. Cold-processed proteins retain more of their natural structure and bioactive compounds compared to heat-treated alternatives. Cross-flow microfiltration and ion-exchange processing preserve protein integrity while removing unwanted fats, lactose, and other components.

Third-party testing certifications ensure products meet label claims and remain free from banned substances. Look for NSF Certified for Sport, Informed Sport, or similar certifications that verify product purity and safety for competitive athletes. These certifications require regular testing for over 200 prohibited substances.

Macronutrient Composition

Beyond protein content, the complete macronutrient profile affects how well a supplement fits into your overall nutrition plan. Low-carbohydrate protein powders contain less than 5 grams of carbs per serving, making them suitable for ketogenic diets or cutting phases when carbohydrate intake is restricted.

Fat content varies significantly between protein types and processing methods. Whey protein isolates typically contain less than 1 gram of fat per serving, while whole milk proteins or less refined powders may contain 2–5 grams. For muscle building phases, moderate fat content can be beneficial, while cutting phases may require minimal fat intake.

Calorie density per serving ranges from 100–150 calories for pure protein powders to 300–400 calories for mass gainer formulations. Understanding calorie content helps ensure your protein supplementation aligns with your overall caloric goals, whether you’re building muscle, maintaining weight, or reducing body fat.

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Types of Protein Supplements: Comprehensive Analysis

Whey Protein: The Gold Standard

Whey protein, derived from milk during cheese production, remains the most popular and well-researched protein supplement for muscle building and recovery. Its complete amino acid profile, high leucine content, and rapid absorption make it ideal for post-workout consumption when muscles are most responsive to protein synthesis signals.

Whey protein concentrate contains 70–80% protein by weight, retaining beneficial compounds like immunoglobulins and lactoferrin while maintaining cost-effectiveness. Whey protein isolate undergoes additional processing to achieve 90–95% protein purity, removing most lactose and fat for those with sensitivities or strict macronutrient requirements.

Hydrolyzed whey protein is pre-digested through enzymatic breakdown, theoretically improving absorption speed and reducing digestive stress. However, the practical benefits over standard whey isolate are minimal for most users, and the significantly higher cost may not justify the marginal improvements in absorption.

Casein Protein: The Nighttime Choice

Casein protein, also derived from milk, forms gel-like structures in the stomach that slow digestion and provide sustained amino acid release over 6–8 hours. This unique property makes casein ideal for nighttime consumption, extended periods between meals, or situations requiring long-lasting protein availability.

Micellar casein represents the highest quality casein form, maintaining the natural protein structure found in milk. This form provides the most sustained release characteristics and contains beneficial bioactive peptides that may support immune function and recovery. Calcium caseinate, while more affordable, undergoes more processing that can alter its natural properties.

Research demonstrates that combining fast and slow proteins can optimize muscle protein synthesis throughout the day. Many athletes use whey protein post-workout for immediate recovery and casein protein before bed to support overnight muscle building and prevent breakdown during extended fasting periods.

Plant-Based Protein Options

Plant-based protein supplements have evolved significantly, now offering complete amino acid profiles and competitive muscle-building potential compared to animal-based alternatives. Pea protein isolate provides excellent leucine content and digestibility while remaining free from common allergens like dairy, soy, and gluten.

Rice protein, particularly brown rice protein, offers good digestibility and amino acid balance when combined with other plant proteins. Hemp protein provides additional benefits through omega-3 fatty acids and fiber content, though it typically contains lower protein concentrations per serving compared to other plant sources.

Comprehensive plant protein blends combine multiple sources like pea, rice, hemp, and quinoa proteins to achieve complete amino acid profiles matching or exceeding animal-based proteins. These blends often include digestive enzymes to enhance absorption and reduce potential digestive discomfort associated with plant proteins.

Timing and Dosage Optimization

Pre-Workout Protein Strategies

Consuming 20–30 grams of easily digestible protein 30–60 minutes before training can enhance muscle protein synthesis during and after exercise. Fast-absorbing proteins like whey protein isolate or hydrolyzed whey are optimal for pre-workout consumption, providing readily available amino acids without causing digestive discomfort during training.

Pre-workout protein consumption helps establish positive nitrogen balance before muscle breakdown occurs during intense training. Research indicates that having elevated blood amino acid levels during exercise can reduce muscle protein breakdown and improve net protein balance post-workout.

Combining pre-workout protein with small amounts of carbohydrates can enhance amino acid uptake and provide additional energy for high-intensity training sessions. However, keep total pre-workout nutrition light to avoid digestive issues during exercise.

Post-Workout Recovery Windows

The post-workout period represents the most critical time for protein consumption, as muscle protein synthesis rates can remain elevated for 24–48 hours following resistance training. Consuming 25–40 grams of high-quality protein within 2 hours post-workout maximizes the muscle-building response to training.

Research suggests that consuming protein immediately post-workout provides minimal advantages over consumption within 2–3 hours, as long as total daily protein intake remains adequate. However, post-workout protein consumption ensures consistent amino acid availability during the peak muscle-building window.

The optimal post-workout protein dose depends on body weight, training intensity, and overall daily protein intake. Larger individuals or those performing high-volume training may benefit from higher protein doses, while smaller individuals or those with adequate daily protein intake may require less.

Daily Protein Distribution

Distributing protein intake evenly throughout the day optimizes muscle protein synthesis compared to consuming large amounts in fewer meals. Aim for 25–40 grams of high-quality protein every 3–4 hours to maintain elevated amino acid levels and support continuous muscle building and recovery.

Research demonstrates that consuming 20–25 grams of protein every 3 hours provides superior muscle protein synthesis compared to uneven distribution or consuming the same total amount in fewer, larger doses. This approach requires strategic use of both whole foods and protein supplements throughout the day.

For individuals with higher protein requirements, such as competitive athletes or those in intensive training phases, protein supplements provide convenient options for meeting elevated needs without excessive food volume or preparation time.

Quality Assessment and Ingredient Considerations

Third-Party Testing and Certifications

Reputable protein supplement manufacturers invest in comprehensive third-party testing to verify product purity, potency, and safety. NSF International, Informed Sport, and BSCG (Banned Substances Control Group) represent the gold standard certifications for sports nutrition products, ensuring products are free from prohibited substances and meet label claims.

Heavy metal testing ensures protein supplements remain free from potentially harmful contaminants like lead, mercury, cadmium, and arsenic that can accumulate in protein sources. Premium manufacturers test every batch and provide certificates of analysis demonstrating compliance with strict safety standards.

Microbiological testing verifies products remain free from harmful bacteria, yeast, mold, and other pathogens that could compromise health or product stability. This testing is particularly important for protein powders, which can provide favorable environments for microbial growth if not properly processed and stored.

Artificial Ingredients and Additives

Many protein supplements contain artificial sweeteners, colors, and flavoring agents to improve taste and appearance. While generally recognized as safe, some individuals prefer natural alternatives or unflavored options to avoid potential sensitivities or long-term health concerns associated with artificial additives.

Natural sweetening options include stevia, monk fruit extract, and coconut sugar, which provide sweetness without artificial compounds. However, naturally sweetened products may have different taste profiles and typically cost more than artificially sweetened alternatives.

Emulsifiers and stabilizers like lecithin help improve powder mixability and texture but aren’t essential for protein function. Some individuals with soy sensitivities should avoid soy lecithin, opting for sunflower lecithin or lecithin-free formulations instead.

Allergen Considerations

Common allergens in protein supplements include milk (whey and casein), soy, eggs, and tree nuts. Individuals with food allergies or intolerances must carefully review ingredient labels and choose appropriate alternatives. Plant-based proteins often provide suitable options for those avoiding animal-derived ingredients.

Cross-contamination during manufacturing can introduce allergens even in products that don’t directly contain them. Facilities that process multiple protein sources may have trace amounts of various allergens, requiring careful consideration for individuals with severe allergies or sensitivities.

Lactose intolerance affects many individuals, making whey protein isolate or plant-based alternatives preferable to whey concentrate or milk-based proteins. Lactase enzyme additions in some products can help individuals with mild lactose intolerance tolerate dairy-based proteins.

Frequently Asked Questions (FAQs)

1. How much protein do I need daily for muscle growth?

Most research suggests consuming 1.6–2.2 grams of protein per kilogram of body weight daily for optimal muscle growth, with athletes and those in intensive training potentially requiring up to 2.5 grams per kilogram. For a 180-pound (82 kg) individual, this translates to approximately 130–180 grams of protein daily. Protein requirements increase during caloric restriction, intense training periods, or when trying to build muscle while losing fat.

2. When is the best time to take protein supplements?

The most important factor is meeting your total daily protein intake rather than precise timing. However, consuming 25–40 grams of protein within 2–3 hours post-workout can optimize muscle protein synthesis. Many people also benefit from protein consumption before bed (casein) or between meals to maintain steady amino acid levels throughout the day.

3. Can I build muscle with plant-based protein supplements?

Yes, plant-based protein supplements can effectively support muscle growth when they provide complete amino acid profiles and adequate leucine content. High-quality plant protein blends combining pea, rice, and other sources can match the muscle-building potential of animal-based proteins. The key is ensuring adequate total protein intake and choosing products with complete amino acid profiles.

4. What’s the difference between whey concentrate and whey isolate?

Whey concentrate contains 70–80% protein by weight and retains more lactose, fat, and beneficial compounds like immunoglobulins. Whey isolate undergoes additional processing to achieve 90–95% protein purity, removing most lactose and fat. Isolate is better for those with lactose intolerance or strict macronutrient requirements, while concentrate offers better value and may provide additional health benefits from retained compounds.

5. Do I need protein supplements if I eat enough protein from food?

Protein supplements aren’t necessary if you consistently meet your protein requirements through whole foods. However, supplements offer convenience, precise dosing, rapid absorption post-workout, and cost-effectiveness compared to some protein-rich foods. They’re particularly useful for busy schedules, travel, or when struggling to meet higher protein requirements through food alone.

6. Can too much protein be harmful?

For healthy individuals, protein intakes up to 2.5–3.0 grams per kilogram of body weight appear safe long-term. However, excessive protein intake may stress the kidneys in individuals with pre-existing kidney disease and can displace other important nutrients if it comprises too much of total caloric intake. Most people don’t need more than 2.2 grams per kilogram unless they’re competitive athletes or in extreme training phases.

7. What should I look for when choosing a protein supplement?

Key factors include protein content per serving (20–30+ grams), complete amino acid profile, third-party testing certifications, minimal artificial additives, and compatibility with your dietary restrictions. Consider your specific needs: fast absorption post-workout (whey isolate), sustained release overnight (casein), or plant-based options for vegan diets. Price per serving and taste preference also matter for long-term compliance.

8. How do I know if a protein supplement is high quality?

High-quality protein supplements feature third-party testing certifications (NSF, Informed Sport), transparent labeling with detailed amino acid profiles, minimal fillers and artificial ingredients, and reputable manufacturing practices. Look for products that specify protein source and processing methods, provide certificates of analysis, and have positive reviews from verified users. Avoid products with proprietary blends that hide specific ingredient amounts.

9. Can women use the same protein supplements as men?

Yes, women can use the same protein supplements as men, as protein requirements are primarily based on body weight, training intensity, and goals rather than gender. Women typically need slightly less total protein due to lower average body weight, but the optimal protein sources and timing remain the same. Some products marketed specifically to women may include additional ingredients like iron or calcium, but standard protein supplements work equally well for both genders.

10. How should I store protein supplements to maintain quality?

Store protein powder in a cool, dry place away from direct sunlight and moisture. Keep containers tightly sealed to prevent exposure to air and humidity, which can cause clumping and nutrient degradation. Avoid storing in refrigerators where condensation can occur when removed. Most protein powders maintain quality for 2–3 years when stored properly, but check expiration dates and look for signs of spoilage like off odors, unusual colors, or texture changes.

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Conclusion: Optimizing Your Protein Supplementation Strategy

Protein supplements represent valuable tools for supporting muscle growth, recovery, and overall athletic performance when used strategically as part of a comprehensive nutrition plan. Understanding the specifications, timing, and quality factors discussed in this guide will help you make informed decisions about incorporating protein supplements into your fitness routine.

Remember that supplements are meant to supplement, not replace, a balanced diet rich in whole food protein sources. The most effective approach combines high-quality protein supplements with nutrient-dense whole foods, proper training, adequate sleep, and consistency in your overall fitness program.

Success in muscle building and recovery depends on multiple factors working together synergistically. While protein supplements can significantly support your goals, they work best when combined with progressive resistance training, adequate caloric intake, proper hydration, and sufficient recovery time between training sessions.

As the sports nutrition industry continues evolving, new protein sources, processing methods, and formulations will emerge. Staying informed about current research and maintaining focus on proven fundamentals will help you navigate these developments and continue making progress toward your fitness goals.

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