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#2022 ACE Anhui
hypeptide 9 months
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Major Advancements in Asymmetric Radical Acylation Unveiled by Anhui Provincial Peptide Drug Lab and Nanjing University in Nature
The Anhui Provincial Peptide Drug Engineering Laboratory (University of Science and Technology of China), in collaboration with a team from Nanjing University, has reported the latest advances in the field of asymmetric radical acylation achieved through photoenzyme catalysis in the journal "Nature."
In recent times, the team led by Professor Tian Changlin from the Anhui Provincial Peptide Drug Engineering Laboratory (Biomedical Department, University of Science and Technology of China, and the High Magnetic Field Science Center, Chinese Academy of Sciences) collaborated with Professor Huang Xiaoqiang's team and Professor Liang Yong's team from Nanjing University to make significant strides in the field of photoenzyme catalysis.
In response to the developed dual catalytic system involving thiamine diphosphate (ThDP)-dependent enzymes and photocatalysis using phosphorus-amino acid (ThDP) as the catalyst, various reaction intermediates, such as free radicals in many reaction processes, changes in the oxidation state of metal catalysts involved in the catalytic reaction, and electron transfer processes during oxidation-reduction, were identified and analyzed using electron paramagnetic resonance (EPR) methods. Professor Tian Changlin's team at the School of Life Sciences, University of Science and Technology of China, has long been engaged in research at the High Magnetic Field Science Center of the Chinese Academy of Sciences, focusing on the identification of free radicals and analysis of electron transfer in research related to high-field EPR equipment setup, low-temperature EPR method development, and the mechanisms of chemical catalysis and enzyme catalysis, achieving a series of research results (Nat Catalysis 2023; Angew Chem Int Ed 2023, PNAS, 2023, 2022; ACS Catalysis 2023, 2021; Chem Commun, 2022, 2021; Science 2018, etc.). Recently, Professor Tian Changlin's team collaborated with Professor Huang Xiaoqiang's team and Professor Liang Yong's team at Nanjing University to make significant progress in the field of photoenzyme catalysis. Using EPR methods, they identified the free radical intermediates in the newly developed catalytic system and the electron transfer mechanism in the catalytic reaction. The research results, titled "A light-driven enzymatic enantioselective radical acylation," were published in Nature (DOI: 10.1038/s41586-023-06822-x).
Biomanufacturing is one of the most promising green technologies for transforming industrial sustainability and is a core aspect of enzyme catalysis in synthetic biology. The combination of enzyme catalysis and photocatalysis, known as photoenzyme catalysis, integrates the diverse reactivity of photochemistry with the high selectivity of enzymes, making it the forefront strategy for developing new enzyme functions. The collaborative research team, using a combination of biomimetic and chemical simulation approaches (Figure 1), harnessed visible light excitation and directed evolution to extend enzyme catalytic functions to radical-radical cross-coupling. Additionally, by using directed evolution to modify ThDP-dependent enzymes, they reshaped ThDP-dependent benzaldehyde lyase into a radical acyl transferase (RAT), achieving a non-natural high enantioselective radical-radical coupling reaction.
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The collaborative team explored the catalytic system of organic dye Rose Bengal and ThDP-dependent enzyme using 4-methoxybenzaldehyde 1a and free radical precursor oxidation-reduction active ester 2a as template substrates. Subsequently, a small and refined mutant library was constructed through molecular dynamics simulations and semi-rational design. The optimal mutant enzyme with high substrate tolerance and substrate selectivity (enantioselectivity up to 97% ee) was obtained, highlighting the finely tuned role of the enzyme's adjustable active pocket in the stereochemical control of free radical stereochemistry (Figure 2).
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For the photoenzyme dual catalytic system, Professor Tian Changlin's team applied low-temperature (80K) electron paramagnetic resonance (EPR) experiments, capturing the ThDP-derived ketyl free radical (Int. B). Through EPR spin trapping experiments, they detected characteristic six-line splitting spectra in the standard reaction system, confirming it as an intermediate benzylic radical (Int. C) and the free radical product after addition with the capture agent. This provided direct evidence for unraveling the key to the new enzyme reactivity and the source of high stereochemical selectivity.
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The collaborative development of a dual catalytic system combining ThDP-dependent enzyme catalysis and organic photosensitizer Eosin Y catalysis, led by Nanjing University and involving the team from the University of Science and Technology of China, not only transformed natural benzaldehyde lyase into a light-driven radical acyl transferase but also achieved excellent stereochemical control of a challenging prochiral free radical. Nanjing University is the first and last corresponding author unit, and the University of Science and Technology of China and the Anhui Provincial Peptide Drug Engineering Laboratory are co-corresponding author units. The aforementioned research work received funding from the National Natural Science Foundation of China's Outstanding Youth Fund, major instrument development projects, and the Ministry of Science and Technology's key research and development program.
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jiannguo 3 years
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Ace Troops on Anhui Sattelite TV 馃コ
Anhui Satellite TV announced the broadcast of Xiao Zhan鈥檚 Ace Troops on 3/20/2022 at 19:30. You can make reservations by clicking on the calendar on Anhui鈥檚 post.
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researchvishal 2 years
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Automotive Oil Strainer Market SWOT Analysis, Dynamics, Drivers, Key Indicators and Forecast to 2022-2032
In accordance with a new FMI report, the automotive oil strainer market is estimated to reach US$ 215.9 million in 2022 and grow at a CAGR of 8.4% from 2022 to 2032. In 2032, the automotive oil strainer market is predicted to be worth US$ 657.1 million.
The rapid expansion of the automotive industry around the world is anticipated to boost the automotive oil strainer market. Rising fuel economy regulations and increasing vehicle emission stringency are predicted to stimulate sales of automotive oil strainers in the coming years.
Intense Competition for Safe Transportation Services May Compel the Expansion of the Automobile Oil Strainer Market
Rising demand for passenger cars, endorsed by the entry of various international automobile manufacturers into largely untapped markets, as well as heavy investments in the development of luxurious and safe transportation systems, are expected to spur market growth. Another important factor that is likely to strengthen the market is increased awareness about the importance of maintaining a healthy air cabin quality.
Due to the technological developments in filter media types, the replacement cycle of automotive oil strainers is points higher. The urgent need to boost oil quality by separating the oil from contaminants to keep it safe and pure is also expected to propel the market during the period of assessment.
Intensity of Rivalry among Top Names and IAM Companies to Stymie the Growth of the Automotive Oil Strainer Market
The automotive transmission oil filter market is made up of various Original Equipment Suppliers (OES) and Independent Aftermarket Suppliers (IAS) (IAM). Several IAM companies that specialize in manufacturing automotive oil strainers are scheduled to compete vehemently with industry giants.
It is likely to occur since IAM players can satisfy customer needs by delivering higher-quality products at a lower cost than Tier 1 companies. The foregoing factors are predicted to push up demand for automotive oil strainers in the years ahead.
North America
According to FMI, North America is projected to stay on top by accumulating the largest automotive oil strainer market share during the assessment period. The increased implementation of stringent regulations as a result of rising awareness about the environmental impact of air pollutants is expected to boost the regional market.
Asia Pacific
A large number of automotive component manufacturers in developing countries is expected to boost sales of automotive oil strainers in the Asia Pacific, according to FMI. Rising demand for synthetic automotive oil strainers due to their high adaptability and reliability to any type of oil is predicted to propel the local market. Furthermore, the rapid expansion of India's automotive industry is expected to bode well for the automotive transmission oil filter market.
聽Key Takeaways
In the year 2029, the automotive transmission oil filter market is expected to be worth US$ 379.71 million.
In the year 2025, the automotive transmission oil filter market is expected to reach US$ 275 million.
The top five players account for more than half of the automotive transmission oil filter market. MAHALE GmbH, AC Delco, Donaldson Company, Tenneco Inc., and Toyota are among them.
North America controls more than 40% of the automotive transmission oil filter market and may maintain its dominance in the future.
Europe's automotive transmission oil filter market is expected to grow at a 3% annual rate.
Japan and South Korea are two of the top five countries propelling the automotive transmission oil filter market forward.
Market Competition
Triple R America, Parker Hannifin Corp., TECNECOFILTRATION, Delphi Auto Parts, Champion Laboratories, Inc., DaikyoNishikawa Corporation, VANTECH CO., LTD., ELOFIC INDUSTRIES LIMITED, ALCO Filters Ltd., Lucas Industries Ltd., and Anhui Meiruier Filter Co. Ltd. are among the key players in the automotive oil strainer market.
The automotive transmission oil filter market is fragmented, with several regional and international companies present. To increase their penetration in highly profitable areas, the majority of the leading players are turning to partnerships with small-scale manufacturers, new product launches, constructive collaborations, and product design changes.
Key Segments Profiled in the Automotive Oil Strainer Industry Survey
By Vehicle Type:
Passenger Cars
Compact Cars
Mid-Sized Cars
Luxury
SUVs
Commercial Vehicles
LCVs (Light Commercial Vehicles)
HCVs (Heavy Commercial Vehicles)
By Cover Type:
Floating Type Automotive Oil Strainer
Fixed Type Automotive Oil Strainer
By Sales Channel:
OEMs
Aftermarket
By Region:
North America
Latin America
Western Europe
Eastern Europe
APEJ
Japan
Middle East and Africa
Recent Development
Agreement
Parker Hannifin Corporation, a global leader in motion and control technologies, announced that it has reached an agreement on the terms of a recommended cash acquisition of Meggitt, a global leader in aerospace and defence motion and control technologies.
Introduction
Delphi Technologies introduces a new global steering and suspension offering for the Tesla Model S, paving the way for a new repair opportunity.
Partnership
Alpine F1 Team is pleased to announce a new partnership with BorgWarner, which expands on the company's long-standing relationship with the Renault Group. BorgWarner purchased Delphi Technologies, and the two companies collaborated on the development of turbochargers and other propulsion technologies, including the current generation of Alpine Cars power units.
For more Information @聽https://www.futuremarketinsights.com/reports/automotive-oil-strainer-market
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ierm-institute 2 years
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Worldwide Transportation Infrastructure Market Size, Share, Trends, Growth, Regional Outlook and Forecast 2017 - Acute Market Reports
In this report, the global Transportation Infrastructure market is valued at USD XX million in 2016 and is expected to reach USD XX million by the end of 2022, growing at a CAGR of XX% between 2016 and 2022.
Browse Full Report Visit - http://www.acutemarketreports.com/report/transportation-infrastructure-market-research
Geographically, this report is segmented into several key Regions, with production, consumption, revenue (million USD), market share and growth rate of Transportation Infrastructure in these regions, from 2012 to 2022 (forecast), covering North America Europe China Japan Southeast Asia India Global Transportation Infrastructure market competition by top manufacturers, with production, price, revenue (value) and market share for each manufacturer; the top players including Bechtel CK Hutchison Group ACS Group Globalvia Inversiones (GVI) VINCI Alstom M+W Group Royal Bam Group Royal Boskalis Westminster CGCOC Group Samsung Engineeringm China Railway Construction POSCO Engineering & Construction Power Construction Corporation of China Anhui Construction Engineering Group Zhejiang Construction Investment Group Zhingding International Engineering On the basis of product, this report displays the production, revenue, price, market share and growth rate of each type, primarily split into Railway Urban Mass Transport Airports Roads and Bridges Ports On the basis on the end users/applications, this report focuses on the status and outlook for major applications/end users, consumption (sales), market share and growth rate of Transportation Infrastructure for each application, including Urban Rural
1 Transportation Infrastructure Market Overview 1.1 Product Overview and Scope of Transportation Infrastructure 1.2 Transportation Infrastructure Segment by Type (Product Category) 1.2.1 Global Transportation Infrastructure Production and CAGR (%) Comparison by Type (Product Category) (2012-2022) 1.2.2 Global Transportation Infrastructure Production Market Share by Type (Product Category) in 2016 1.2.3 Railway 1.2.4 Urban Mass Transport 1.2.5 Airports 1.2.6 Roads and Bridges 1.2.7 Ports 1.3 Global Transportation Infrastructure Segment by Application 1.3.1 Transportation Infrastructure Consumption (Sales) Comparison by Application (2012-2022) 1.3.2 Urban 1.3.3 Rural 1.4 Global Transportation Infrastructure Market by Region (2012-2022) 1.4.1 Global Transportation Infrastructure Market Size (Value) and CAGR (%) Comparison by Region (2012-2022) 1.4.2 North America Status and Prospect (2012-2022) 1.4.3 Europe Status and Prospect (2012-2022) 1.4.4 China Status and Prospect (2012-2022) 1.4.5 Japan Status and Prospect (2012-2022) 1.4.6 Southeast Asia Status and Prospect (2012-2022) 1.4.7 India Status and Prospect (2012-2022) 1.5 Global Market Size (Value) of Transportation Infrastructure (2012-2022) 1.5.1 Global Transportation Infrastructure Revenue Status and Outlook (2012-2022) 1.5.2 Global Transportation Infrastructure Capacity, Production Status and Outlook (2012-2022)
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2 Global Transportation Infrastructure Market Competition by Manufacturers 2.1 Global Transportation Infrastructure Capacity, Production and Share by Manufacturers (2012-2017) 2.1.1 Global Transportation Infrastructure Capacity and Share by Manufacturers (2012-2017) 2.1.2 Global Transportation Infrastructure Production and Share by Manufacturers (2012-2017) 2.2 Global Transportation Infrastructure Revenue and Share by Manufacturers (2012-2017) 2.3 Global Transportation Infrastructure Average Price by Manufacturers (2012-2017) 2.4 Manufacturers Transportation Infrastructure Manufacturing Base Distribution, Sales Area and Product Type 2.5 Transportation Infrastructure Market Competitive Situation and Trends 2.5.1 Transportation Infrastructure Market Concentration Rate 2.5.2 Transportation Infrastructure Market Share of Top 3 and Top 5 Manufacturers 2.5.3 Mergers & Acquisitions, Expansion
3 Global Transportation Infrastructure Capacity, Production, Revenue (Value) by Region (2012-2017) 3.1 Global Transportation Infrastructure Capacity and Market Share by Region (2012-2017) 3.2 Global Transportation Infrastructure Production and Market Share by Region (2012-2017) 3.3 Global Transportation Infrastructure Revenue (Value) and Market Share by Region (2012-2017) 3.4 Global Transportation Infrastructure Capacity, Production, Revenue, Price and Gross Margin (2012-2017) 3.5 North America Transportation Infrastructure Capacity, Production, Revenue, Price and Gross Margin (2012-2017) 3.6 Europe Transportation Infrastructure Capacity, Production, Revenue, Price and Gross Margin (2012-2017) 3.7 China Transportation Infrastructure Capacity, Production, Revenue, Price and Gross Margin (2012-2017) 3.8 Japan Transportation Infrastructure Capacity, Production, Revenue, Price and Gross Margin (2012-2017) 3.9 Southeast Asia Transportation Infrastructure Capacity, Production, Revenue, Price and Gross Margin (2012-2017) 3.10 India Transportation Infrastructure Capacity, Production, Revenue, Price and Gross Margin (2012-2017)
4 Global Transportation Infrastructure Supply (Production), Consumption, Export, Import by Region (2012-2017) 4.1 Global Transportation Infrastructure Consumption by Region (2012-2017) 4.2 North America Transportation Infrastructure Production, Consumption, Export, Import (2012-2017) 4.3 Europe Transportation Infrastructure Production, Consumption, Export, Import (2012-2017) 4.4 China Transportation Infrastructure Production, Consumption, Export, Import (2012-2017) 4.5 Japan Transportation Infrastructure Production, Consumption, Export, Import (2012-2017) 4.6 Southeast Asia Transportation Infrastructure Production, Consumption, Export, Import (2012-2017) 4.7 India Transportation Infrastructure Production, Consumption, Export, Import (2012-2017)
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5 Global Transportation Infrastructure Production, Revenue (Value), Price Trend by Type 5.1 Global Transportation Infrastructure Production and Market Share by Type (2012-2017) 5.2 Global Transportation Infrastructure Revenue and Market Share by Type (2012-2017) 5.3 Global Transportation Infrastructure Price by Type (2012-2017) 5.4 Global Transportation Infrastructure Production Growth by Type (2012-2017)
6 Global Transportation Infrastructure Market Analysis by Application 6.1 Global Transportation Infrastructure Consumption and Market Share by Application (2012-2017) 6.2 Global Transportation Infrastructure Consumption Growth Rate by Application (2012-2017) 6.3 Market Drivers and Opportunities 6.3.1 Potential Applications
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Global Levulinic Acid Market Share, Size, Growth, Trends, Industry Analysis and Forecast 2017 By Acute Market Reports
In this report, the global Levulinic Acid market is valued at USD XX million in 2016 and is expected to reach USD XX million by the end of 2022, growing at a CAGR of XX% between 2016 and 2022.
Browse Full Report Visit - http://www.acutemarketreports.com/report/levulinic-acid-sales-market
Geographically, this report split global into several key Regions, with sales (K MT), revenue (Million USD), market share and growth rate of Levulinic Acid for these regions, from 2012 to 2022 (forecast), covering United States China Europe Japan Southeast Asia India
Global Levulinic Acid market competition by top manufacturers/players, with Levulinic Acid sales volume, Price (USD/MT), revenue (Million USD) and market share for each manufacturer/player; the top players including Biofine International Inc Avantium GFBiochemicals Ltd Langfang Triple Well Chemicals Co. Ltd Simagchem Corporation Hefei TNJ Chemical Industry Co., Ltd Great Chemicals Co. Ltd. Anhui Herman Impex Co Ltd Shandong Zibo Shuangyu Chemical Co., Ltd On the basis of product, this report displays the sales volume (K MT), revenue (Million USD), product price (USD/MT), market share and growth rate of each type, primarily split into Manufactured by Chemical Methods Manufactured by Biological Methods On the basis on the end users/applications, this report focuses on the status and outlook for major applications/end users, sales volume, market share and growth rate of Levulinic Acid for each application, including Plastic Modifier Pharmaceutical Flavors Cosmetics Pesticides Solvent Other Chemical Additives
1 Levulinic Acid Market Overview 1.1 Product Overview and Scope of Levulinic Acid 1.2 Classification of Levulinic Acid by Product Category 1.2.1 Global Levulinic Acid Market Size (Sales) Comparison by Type (2012-2022) 1.2.2 Global Levulinic Acid Market Size (Sales) Market Share by Type (Product Category) in 2016 1.2.3 Manufactured by Chemical Methods 1.2.4 Manufactured by Biological Methods 1.3 Global Levulinic Acid Market by Application/End Users 1.3.1 Global Levulinic Acid Sales (Volume) and Market Share Comparison by Application (2012-2022) 1.3.2 Plastic Modifier 1.3.3 Pharmaceutical 1.3.4 Flavors 1.3.5 Cosmetics 1.3.6 Pesticides 1.3.7 Solvent 1.3.8 Other Chemical Additives 1.4 Global Levulinic Acid Market by Region 1.4.1 Global Levulinic Acid Market Size (Value) Comparison by Region (2012-2022) 1.4.2 United States Levulinic Acid Status and Prospect (2012-2022) 1.4.3 China Levulinic Acid Status and Prospect (2012-2022) 1.4.4 Europe Levulinic Acid Status and Prospect (2012-2022) 1.4.5 Japan Levulinic Acid Status and Prospect (2012-2022) 1.4.6 Southeast Asia Levulinic Acid Status and Prospect (2012-2022) 1.4.7 India Levulinic Acid Status and Prospect (2012-2022) 1.5 Global Market Size (Value and Volume) of Levulinic Acid (2012-2022) 1.5.1 Global Levulinic Acid Sales and Growth Rate (2012-2022) 1.5.2 Global Levulinic Acid Revenue and Growth Rate (2012-2022)
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2 Global Levulinic Acid Competition by Players/Suppliers, Type and Application 2.1 Global Levulinic Acid Market Competition by Players/Suppliers 2.1.1 Global Levulinic Acid Sales and Market Share of Key Players/Suppliers (2012-2017) 2.1.2 Global Levulinic Acid Revenue and Share by Players/Suppliers (2012-2017) 2.2 Global Levulinic Acid (Volume and Value) by Type 2.2.1 Global Levulinic Acid Sales and Market Share by Type (2012-2017) 2.2.2 Global Levulinic Acid Revenue and Market Share by Type (2012-2017) 2.3 Global Levulinic Acid (Volume and Value) by Region 2.3.1 Global Levulinic Acid Sales and Market Share by Region (2012-2017) 2.3.2 Global Levulinic Acid Revenue and Market Share by Region (2012-2017) 2.4 Global Levulinic Acid (Volume) by Application
3 United States Levulinic Acid (Volume, Value and Sales Price) 3.1 United States Levulinic Acid Sales and Value (2012-2017) 3.1.1 United States Levulinic Acid Sales and Growth Rate (2012-2017) 3.1.2 United States Levulinic Acid Revenue and Growth Rate (2012-2017) 3.1.3 United States Levulinic Acid Sales Price Trend (2012-2017) 3.2 United States Levulinic Acid Sales Volume and Market Share by Players 3.3 United States Levulinic Acid Sales Volume and Market Share by Type 3.4 United States Levulinic Acid Sales Volume and Market Share by Application
4 China Levulinic Acid (Volume, Value and Sales Price) 4.1 China Levulinic Acid Sales and Value (2012-2017) 4.1.1 China Levulinic Acid Sales and Growth Rate (2012-2017) 4.1.2 China Levulinic Acid Revenue and Growth Rate (2012-2017) 4.1.3 China Levulinic Acid Sales Price Trend (2012-2017) 4.2 China Levulinic Acid Sales Volume and Market Share by Players 4.3 China Levulinic Acid Sales Volume and Market Share by Type 4.4 China Levulinic Acid Sales Volume and Market Share by Application
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5 Europe Levulinic Acid (Volume, Value and Sales Price) 5.1 Europe Levulinic Acid Sales and Value (2012-2017) 5.1.1 Europe Levulinic Acid Sales and Growth Rate (2012-2017) 5.1.2 Europe Levulinic Acid Revenue and Growth Rate (2012-2017) 5.1.3 Europe Levulinic Acid Sales Price Trend (2012-2017) 5.2 Europe Levulinic Acid Sales Volume and Market Share by Players 5.3 Europe Levulinic Acid Sales Volume and Market Share by Type 5.4 Europe Levulinic Acid Sales Volume and Market Share by Application
6 Japan Levulinic Acid (Volume, Value and Sales Price) 6.1 Japan Levulinic Acid Sales and Value (2012-2017) 6.1.1 Japan Levulinic Acid Sales and Growth Rate (2012-2017) 6.1.2 Japan Levulinic Acid Revenue and Growth Rate (2012-2017) 6.1.3 Japan Levulinic Acid Sales Price Trend (2012-2017) 6.2 Japan Levulinic Acid Sales Volume and Market Share by Players 6.3 Japan Levulinic Acid Sales Volume and Market Share by Type 6.4 Japan Levulinic Acid Sales Volume and Market Share by Application
7 Southeast Asia Levulinic Acid (Volume, Value and Sales Price) 7.1 Southeast Asia Levulinic Acid Sales and Value (2012-2017) 7.1.1 Southeast Asia Levulinic Acid Sales and Growth Rate (2012-2017) 7.1.2 Southeast Asia Levulinic Acid Revenue and Growth Rate (2012-2017) 7.1.3 Southeast Asia Levulinic Acid Sales Price Trend (2012-2017)
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