lucifers-simp

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op made this unrebloggable but i still want everyone to see the trea turner faggot in the back tweet

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i think minecraft could be so much better of a game if they added watermelon in game

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1 second of every star trek tos episode enjoy

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Not to sound like the oldest person ever but I think vaping is so fucking stupid. you wanna smoke? man up and buy a pack of cigarettes. or a bong or something. It's somehow healthier compared to a vape. and like, yeah it's bad for you but you know that already, i just don't think cancer in a box should come in the shape of hello kitty and taste like cotton candy. oh yea let me go get my mlp cocaine with edible glitter. my minecraft movie heroin. my sonic amphetamine. my super mario mushrooms

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I approve of powerscaling discourse only in utterly senseless contexts. I don't give a shit about which shōnen protagonists could beat up which other shōnen protagonists, but I will 100% read your five thousand word essay exploring the subtle nuances of establishing a tiered ranking of the Smurfs.

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*dies hundreds of years ago as the village fool* well that fucking sucked lol let’s try again *reincarnated as a tumblr user* FUUUUUUCK

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WARNING do NOT start reading books and comics or watching movies or looking at art!!! you will start wanting to create art yourself. or god forbid. writing.

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My fave part of this tweet is that even though a lot of people are assuming this was an AI thing or whatever

this is the actual lede of their review of the Super Mario movie

"But it is also, if I check the clock, Mario Time". Poetry

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“X bodily fluid is just filtered blood!” buddy I hate to break it to you but ALL of the fluids in your body are filtered blood. Your circulatory system is how water gets around your body. It all comes out of the blood (or lymph, which is just filtered blood).

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Hey, can you say " " if you support trans rights? :)

‎

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Sound Designer problems.

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"tumblr humor is only funny to tumblr users" NOT true. those bitches on pinterest love us.

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He’s so cool

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i love when ppl draw elias bouchard wearing like anachronistic ass emerald green waistcoats and a monocle in their fanart bc it makes s1 so much funnier to think about. like you know what? yeah actually if i was jonathan sims and my fucking freak of a boss dressed like that and did an evil monologue voice at all times and paid me to read ghost stories in his basement all day, i would also probably be like "yeah this is a deeply unserious job and i am the only normal person here. sick paycheck tho" and then clock the fuck out without ever thinking about those fuckass statements again!! like what are we dunking on him for!! who would chalk that up to anything other than "my weirdass boss has clearly taken his eccentric edwardian magician LARP too far but goddamn if that check doesn't come in every month"

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"Tim Friede’s YouTube channel is home to a collection of videos depicting the Wisconsin-native truck mechanic subjecting himself to purposeful snake bites, blood slowly dripping down his arms.

For the past 20 years, Friede has been one of the most notorious “unconventional” medical researchers, undergoing over 200 bites from the world’s deadliest snakes — and more than four times as many — 850 — venomous injections. 

He did it all in the name of science.

According to the World Health Organization, an estimated 100,000 people are killed by snake bites each year, with countless more being disabled by the venom of the deadly reptiles. 

While life-saving anti-venom is available, very few countries actually have the capacity to produce it properly, given that most bites occur in remote and rural areas, and anti-venom requires arduous sourcing and accuracy. 

But Friede’s blood is now full of antibodies, following decades of strategic exposure to the neurotoxins of mambas, cobras, and other lethal slithering critters.

His blood is now the source material researchers are using to develop an anti-venom capable of neutralizing a broad spectrum of snake bites...

Friede started this hobby — which he is indeed adamant no one else tries at home — out of sheer curiosity in childhood. After playing with harmless garter snakes in his youth, he began keeping more dangerous species of snakes as pets. At one point, he had 60 of them in his home basement.

In 1999, he began extracting venom from his snakes, drying it, diluting it, and injecting himself with tiny doses — keeping meticulous records as he went.

He had one major hospitalization in 2001, when he was paralyzed and in a coma for four days. But instead of giving up, he doubled down. 

“In hindsight, I’m glad it happened,” Friede told The Times. “I never made another mistake.”

Jacob Glanville, an immunologist and founder of biotech company Centivax, stumbled on Friede’s videos.

Now, Friede is the director of herpetology at Centivax and serves as something of a “human lab” to Glanville.

“For a period of nearly 18 years, [Tim] had undertaken hundreds of bites and self-immunizations with escalating doses from 16 species of very lethal snakes that would normally a kill a horse,” Glanville told The Guardian.

“It blew my mind. I contacted him because I thought if anyone in the world has these properly neutralizing antibodies, it’s him.”

To develop the new anti-venom, Glanville and his fellow researchers identified 19 of the world’s deadliest snakes — in the elapid family — which kill their prey by injecting neurotoxins into their bloodstream, paralyzing muscles (including the big, important ones, like the heart and lungs).

The trouble is, each species in the elapid family has a slightly different toxin, meaning they would each require their own anti-venom.

But Friede’s blood contains certain fragments of each of these toxins; protein molecules seen across the various species. Because of his decades of service to science, his blood also contains the antibodies required to neutralize these toxins, preventing them from sticking to human cells and causing harm.

Combining the antibodies LNX-D09, SNX-B03, and a small molecule called varespladib that inhibits venom toxins, Centivax has successfully created a treatment effective against the entire range of 19 species’ toxins.

Their work, which was recently published in the journal Cell, will soon be tested outside of the lab. 

Trials will start with using the serum to treat dogs admitted to Australian veterinary clinics for snake bites. Assuming that goes well, the next step will be to administer human tests.

Researchers also believe that because the serum stems from a human, this should also lower the risk of allergic reactions when being administered to other people. 

“The final product would be a single, pan-anti-venom cocktail,” Professor Peter Kwong of Columbia University, a senior author of the study, told The Times.

Or, he added, they could make two: “One that is for the elapids, and another that is for the viperids, because some areas of the world only have one or the other.”

As for Friede, he maintains his affinity for snakes, though his last bite was in November 2018, when he said “enough is enough,” according to The New York Times.

By then, he had certainly done enough. His pursuit of immunity could feasibly save countless lives.

“I’m really proud that I can do something in life for humanity,” Friede told The New York Times, “to make a difference for people that are 8,000 miles away, that I’m never going to meet, never going to talk to, never going to see, probably.”

-via GoodGoodGood, May 2, 2025

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