mindfulcells

[mindfulcells]

Navigating Mountain Roads To A New Chapter

Mira's life-changing journey with lymphoma warrior - find out how CAR T therapy offers hope for beating Lymphoma. #Lymphoma #lymphomawarrior #lymphomaawareness #carttherapy

[mindfulcells]

Mira's Lymphoma Warrior Journey: Hope and CAR-T Therapy

Estimated reading time: 7 minutes The bold headlines proclaimed the promise of CAR T therapy and its efficacy in combating lymphoma’s relentless grip. Mira – a woman who had weathered the storm of cancer diagnosis, treatment, and remission. She paused to reflect on hope with her life-changing lymphoma warrior journey. As the city’s symphony of car horns echoed outside her window, she stepped…

[mindfulcells]

NexCAR19 CAR T Cell Therapy: Tailoring the Approach to B-Cell Lymphoma Treatment

NexCAR19 CAR T cell therapy is a groundbreaking treatment for B-cell lymphomas that has recently received approval in India. This innovative therapy harnesses the power of the patient's own immune system to fight cancer cells.

NexCAR19 is a CAR T cell therapy product that uses a unique humanized 'h1CAR19-8BBζ CAR' construct.

This construct favors CD4+ and CD8+ T cell subsets, cytokine secretion, and antitumor function.

Preclinical and clinical studies have demonstrated safety and remarkable efficacy in B-cell lymphoma patients.

Read more

[mindfulcells]

Restoring Dopamine Production in Parkinson's Disease?

Replacing Lost Neurons in Parkinson's Disease with Bemdaneprocel and ANPD001 cell therapies

Bemdaneprocel dopaminergic neuron cell therapy by BlueRock Therapeutics, A Bayers company 

Key points 

Focus on Allogeneic therapy – a drug product developed from human embryonic stem cells.

Recently completed Phase I study. 

One-year interim data presents 

Dopaminergic neurons survived and engrafted into the brain upon surgical implantation

High dose cohort presented improvement in "on" status (2.16 hr)

Low dose cohort showed improvement in "on" status (0.72 hr)

BlueRock Therapeutics is starting Phase II very soon.

ANPD001 Dopaminergic neuron precursor cell therapy by Aspen Neuroscience recently received FDA clearance, to begin with clinical trial

Focus on autologous therapy, i.e., collecting patient skin cells, reprogramming them to iPSCs, and developing dopamine neuronal precursor cells as a drug product. 

Phase 1 clinical trial starts soon.

[mindfulcells]

GABAergic interneuron cell therapy reduces 95% of seizures and improves cognitive function—the interim data from Phase 1/2 clinical trial presented by Neurona Therapeutics.

[mindfulcells]

Stemirac® is a PMDA approved stem cell therapy for spinal cord injury that is showing promising results in clinical trials. Mesenchymal stem cells (MSCs), like those used in Stemirac®, can help to repair damaged tissue and improve quality of life for patients with spinal cord injury.

[mindfulcells]

Unleashing the Power Within: A Patient's Guide to CAR-T Therapy

Discover the potential of CAR-T therapy to unleash the power within: Explore ongoing trials, FDA-approved products, and side effect management. #carttherapy, #celltherapy, #cartcelltherapy, #immunotherapy, #USFDA, #FDAapproval, #lymphoma, #lymphomaawareness, #leukemia, #leukemiaawareness, #Myeloma, #myelomaawareness,

Welcome to MindfulCells Blog, your patient ultimate guide to CAR-T cell therapy, a groundbreaking form of immunotherapy revolutionizing cancer treatment. Discover how this incredible FDA approved CAR T treatment harnesses your immune system’s power to combat cancer cells and transform lives. CAR T therapyIt combines cell and gene therapy – T cells and CAR T cells are a type of white blood cells…