#Clostridioides difficile and COVID-19

[consultatiiladomiciliu-ro]

Noul vaccin ARNm poate proteja împotriva infecțiilor cu Clostridium difficile

Un grup de cercetători de la Universitatea din Pennsylvania, Philadelphia, a dezvoltat un vaccin cu ARN mesager (ARNm), furnizat prin nanoparticule lipidice (LNP) – același tip ca vaccinul COVID-19 produs de Moderna și Pfizer – care vizează Clostridioides difficile (fostul Clostridium difficile), o bacterie anaeroba care produce in toata lumea civilizata boli intestinale grave (letale) la…

[youngscientist96]

An mRNA vaccine protected mice against deadly intestinal C. difficile bacteria

Clostridioides difficile is a notoriously nasty intestinal bug, with few effective treatments and no approved vaccines. But the same technology that enabled the first COVID-19 vaccines has shown early promise, in mouse experiments, against this deadly infection, which kills 30,000 people in the United States each year.

An mRNA vaccine designed to target C. difficile and the toxins it produces protected mice from severe disease and death after exposure to lethal levels of the bacterial pathogen, researchers report in the Oct. 4 Science. While it will take much more research to see whether the vaccine is safe and effective for humans, the results hint that an mRNA vaccine might succeed where more conventional vaccines have failed.

#MRNAVaccine #ClostridiumDifficile #Cdiff #MedicalResearch #InfectiousDisease #IntestinalHealth #VaccineDevelopment #BiomedicalResearch #GutHealth #Immunotherapy #Biotechnology #AntibioticResistance #HealthInnovation #Microbiology #Vaccines

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[cdifffoundation]

C. diff. Spores and More Live Broadcast Enters Season VI

C. diff. Spores and More Live Broadcast Enters Season VI

Welcome to Season VI on  C. diff. Spores and More Live Broadcast, sponsored by Clorox Healthcare.   With over 260 archived episodes ~ Listen At Your Leisure It’s a new year with an entirely new line up of guests eager to share their C. difficile research, infection prevention methods, clinical trials in progress, the updates in the C. diff. community, and much more.         In March the…

[benefitsofhandsanitizer]

9 Important Benefits of Using Hand Sanitizer

When ran out of hand sanitizer during the COVID-19 pandemic of 2021, The CDC recommends using Hand Sanitizer with Alcohol to help stop the spread of germs.

Hand sanitizer isn’t more effective than washing your hands, but it’s definitely more convenient. Here are 9 benefits of using hand sanitizer.

1. Waterless One of the biggest benefits of using hand sanitizer over soap is that you don’t need to be near a sink. There are many instances where the need to rinse your hands is highly inconvenient.

You might not be near running water or have to wait in long lines at a public restroom to get access to a sink. Hand sanitizer is similar to using lotion in that it requires no other resources or prep work in order to use it.

2. Portable You can never replace the use of hand sanitizer with hand soap while on the go. Soap isn’t portable and won’t remove any pathogens from your hands unless you have water to rinse them off.

Portability makes hand sanitizer a smart choice for protecting your hands from germs throughout the day. Keep a bottle handy in your pocket or briefcase to use after you come in contact with surfaces in public spaces.

Food trucks and other street food vendors won’t have a place for you to wash your hands before eating. Having your own hand sanitizer gives you the option to clean your hands before you eat.

3. Kills Microorganisms It’s very common for bacteria to live on your hands, but not viruses. Still, you want the option to remove both while you’re out on the go.

Bacteria on your hands usually fall into two categories: resident and transient. The resident bacteria lives underneath a thin layer of skin cells on your hands.

Transient bacteria lives just on the surface and is easily removed. When you use hand sanitizer or wash your hands, you’re mostly removing transient bacteria.

According to the CDC, soap and water are better than hand sanitizers at removing germs like norovirus, Cryptosporidium, and Clostridioides difficile, and some harsh chemicals. But hand sanitizers still kill many germs on the surface of your skin.

Unlike soap, hand sanitizers kill germs on contact. The key is making sure your hand sanitizer has at least the minimum amount of alcohol needed to kill as many microorganisms as possible.

4. Good for Sensitive Skin One common complaint about hand soap is that certain formulas are irritating for sensitive skin. Using commercial grade soaps found in public restrooms might contain ingredients that lead to rashes or itching on your skin.

Applying hand sanitizer is usually much better for sensitive skin especially if you’re using your own recipe.

5. Shareable Hand sanitizer is great to have because it’s easy to share in groups. One Harvard study showed that most people aren’t truthful about washing their hands after using public restrooms.

If you’re in a group setting, share your hand sanitizer before sharing a meal with friends or coworkers. This cuts back on having to trust that everyone practices the same level of hygiene.

If you’re especially germaphobic, squeeze the hand sanitizer into the hands of everyone in the group instead of passing the bottle around. This creates a completely touchless situation for everyone.

6. Moisturizing Another important benefit of using hand sanitizer is that it’s more moisturizing than soap. Depending on its ingredients, hand sanitizer can be just as moisturizing as some lotions or oils.

If your skin dries out after washing your hands, create a hand sanitizer recipe to help keep your hands soft throughout the day. 

7. Bacteria Can’t Become Resistant

Bacteria won’t become resistant to the ingredients of hand sanitizer like they can with soap. Antibacterial soaps use an ingredient called Triclosan which has been suspected of worsening the strains of antibiotic-resistant bacteria present on the hands.

There is no similar concerns with hand sanitizer. The active ingredient in hand sanitizers is alcohol.

Alcohol has been used for thousands of years as an antiseptic. It kills bacteria through a process called denaturation. This is just a way of saying alcohol can completely dissolve bacteria.

8. Fast A common reason people don’t wash their hands is that it’s faster just to walk away after using the bathroom. If you’ve got to walk to the bathroom before getting a snack and you’re really hungry, it’s easy to find an excuse to skip hand washing in order to satisfy your hunger faster.

Hand sanitizer is far more convenient because it’s fast. There’s no washing with soap and water for 20 seconds to make sure you’ve removed all germs. Simply, rub for a few seconds and go.

Benefits of Using Hand Sanitizer to Prevent Illness The benefits of hand sanitizer during a viral outbreak are tremendous. Killing pathogens on your hands can be the difference between infecting someone you love with germs or keeping your family safe.

[cardamomoespeciado]

Case fatality rate over 30%, super-resistant bacteria are spreading in the shadow of corona

National Geographic Japan version

Candida auris, difficult to treat and disinfect, warns doctors around the world

Case fatality rate over 30%, super-resistant bacteria are spreading in the shadow of corona

CG illustration of Candida auris. The unicellular fungus Candida auris was first reported in 2009. It has strong drug resistance, is easily spread by nosocomial infections, and has a high mortality rate. (SCIENCE PHOTO LIBRARY / ALAMY STOCK PHOTO)

While the new coronavirus infection (COVID-19) is rampant worldwide, infection with the super (ultra-multidrug) resistant bacterium Candida auris (both Candida auris), which may be resistant to all drugs Is expanding in part, doctors are warning. Candida auris is particularly susceptible to nosocomial infections, which puts a heavy burden on the medical field, which is flooded with corona patients this year.

Candida auris adheres to sheets, bed railings, doors, medical equipment, etc. and survives for a long time, and when touched by human hands, the infection spreads. In addition, there is a high risk of infection when inserting a tube into the body, such as a catheter, ventilator, or liquid food. Patients hospitalized in Corona are often exposed to these measures because of respiratory problems.

"Unfortunately, Candida auris is expanding in some areas," said Tom Chiller, director of mycosis at the Centers for Disease Control and Prevention (CDC). "Some have spread to emergency hospitals and corona wards. Once an infection is discovered, it's difficult to get rid of it completely, so I'm very worried."

The Candida fungus was originally known to cause mild symptoms such as white spots on the tongue and genitals. However, Candida auris has been reported in at least 40 countries since it was first reported by Professor Koichi Makimura of Teikyo University in 2009, and thousands of people have been infected. Although the pathogenicity of the Japanese type is low, there is also a type with a mortality rate of 30 to 60%.

Candida auris is not the only bacterium that is resistant to drugs. Already, millions of people worldwide are infected with various super-resistant strains, and the spread of Candida auris could exacerbate the crisis. In 2019, the CDC positioned Candida auris as one of the greatest threats among drug-resistant bacteria in the United States. By the end of August this year, 1364 cases have been confirmed in the United States. It is more than four times the number of infected people in 2018 as a whole.

However, this year, there are many cases of Candida auris that are overlooked behind the new Corona, and the actual number seems to be much higher than that. Even if the bacteria adhere to human skin, they may not show any symptoms. It is possible that the death toll from super-resistant bacteria is among the excess mortality surges during the new corona epidemic. That's why doctors around the world are ringing the alarm.

Severely ill corona infected in hospital or 6 out of 10 dead

It was 2011. Several blood samples have been sent to Anurada Chaudhry, who worked at a laboratory in New Delhi, India. A mysterious fungal infection was spreading in the intensive care unit and neonatal room of two hospitals in the city.

Mr. Chaudhry, a professor of medical mycology at the Valabby Patel Chest Institute at the University of Delhi, was asked to identify the fungus and propose a therapeutic drug. After seeing the results of the analysis, Mr. Chaudhry twisted his head.

"Candida auris? What's that?"

It's no wonder Mr. Chaudley didn't know. Candida auris was first reported only two years ago. Found in the ears of a patient, it was named "Auris," which means ear in Latin.

What surprised me most was that fluconazole, the first treatment used for fungal infections, had no effect on Mr. Chaudley's blood samples. In 2013, Candida Auris published a paper on the subject, which was later revealed to be resistant to fluconazole and other azoles. Also, even the other two major types of antibiotics may not work.

Currently, Mr. Chowdley is studying a patient with candidaemia among the severely ill patients of the new corona who entered the intensive care unit in Delhi. It is a disease caused by Candida albicans entering the blood.

According to the results of a small study published in the November issue of the medical journal "Emerging Infectious Diseases" by Mr. Caudley et al., Candida auris was found in 10 out of 15 patients. Both are believed to have been infected in the hospital.

All blood samples were resistant to fluconazole, and 4 of the strains isolated from the blood did not respond to the other antibacterial drug amphotericin B. The last hope, Echinocandin, is difficult to obtain in India. Eventually, six people died.

Mr. Chaudley, like the new Corona, argues that testing and contact tracking are important to control the spread of Candida auris. The Candida auris test is done by rubbing the surface of the skin or by collecting blood or urine. Patients who test positive will be examined for the effects of three antibiotics.

In this way, it is possible to identify the number of deaths due to super-resistant bacteria to some extent, but the fact that it is easily infected in the hospital complicates the problem. In hospitals, patients already have other illnesses, such as corona, and it is difficult to determine whether the cause of death is due to the illness or drug-resistant bacteria.

Climate change and pandemics

In 2019, the World Health Organization (WHO) listed drug-resistant bacteria as one of the top 10 threats to human health, returning to a world where tuberculosis and even gonorrhea, which are now easily treated, are out of control. He expressed concern that it would end up.

It is said that the abuse of antibacterial drugs in the medical field of livestock and humans worldwide gave birth to super-resistant bacteria. But climate variability predicts that fungal infections will spread further in the future, said Ramanan Laxminarayan, founder and representative of the Center for Pathological Economic Policy (CDDEP) in Washington, D.C.

A paper published last year in the American Society for Microbiology journal "mBio" stated that "Candida auris may be the first fungal infection born of climate variability."

Humans tend to have a fever as a defensive reaction when they get an infectious disease. This is because the fungus is sensitive to heat. However, if fungi such as Candida auris adapt to hot environments due to global warming, their defenses may be ineffective. This means that in the future, not only will existing fungi expand, but new fungal infections may emerge.

"Just as more bacteria aren't working with antibiotics, fungi that aren't working with antibacterial drugs may threaten humanity," Lacus Minarayan warns. Strong bacteria such as multidrug-resistant M. tuberculosis and Clostridioides difficile, whose cases are rapidly increasing mainly in North America, account for 99% of the 2.8 million super-resistant bacterial infections in the United States annually. The death toll is about 35,000.

India, which has long been said to be a hotbed for fostering drug resistance, is now the center of the epidemic of the new coronavirus disease. In Mr. Chaudley's lab, about half of the staff were also tested positive for corona in recent tests, killing two. Mr. Chaudhry welcomes people as they begin to realize the threat of Candida auris in a difficult personal situation.

"Many people thought it was an Indian problem and had nothing to do with them. So far I've been studying alone and I've had a hard time, but now the world is working on it. Fungal infections are diseases that should never be ignored. "

[simplicitygifts]

Take Care of Yourself with Proper Hand Hygiene

The biggest boon emerging from the Covid-19 pandemic is the way people have come to recognize the value of personal hygiene, especially of hand hygiene. Normally, washing one’s hands thoroughly with soap and water should suffice. However, the experience of these two years has demonstrated that it is not practical to keep washing one’s hands with soap and water every time you touch some kind of surface. Under such circumstances, it makes better sense to use hand sanitizers.

Halt the Spread of Contagious Diseases

When ordering a customized hand sanitizer in Singapore, keep in mind that the CDC recommends the use of a hand sanitizer which has a minimum alcohol content of 60 percent to kill germs which lie on the skin. These exclude norovirus, Cryptosporidium, and Clostridioides difficile, apart from chemicals and heavy metals, which can only be killed or removed from the skin using soap and water. You should use the hand sanitizer correctly to get maximum benefit from it. This means that you must not wipe your hands before they dry as that would reduce its effectiveness in fighting germs. Apply the liquid to the palm of one hand. Then rub it all over both hands until the sanitizer dries.

Keep Hand Sanitizer Bottles Always Accessible

Whether you are at home or in office, a bottle of hand sanitizer should always be kept from where you can reach it easily. Otherwise, if you have to rummage through a drawer of your desk, or through your handbag when you need to sanitize your hands because you had touched a surface which might be contaminated; then the entire purpose will be defeated. You must use a sanitizer immediately after sneezing or coughing. This will help you to ward off the corona virus infection.

Get the Quantity Which Suits You Best

It is not necessary for you to buy a 100 ml. bottle, if you are going to be the only one using the hand sanitizer, especially when you are on the road. Then, you might look at one of the 30 ml. travel hand sanitizer packs. If you are gifting the hand sanitizer, or ordering for your office colleagues, then get the company logo printed on the bottle of the customized hand sanitizer. Just make sure that it contains at least 75% medical grade alcohol.

Caution:  Do not use hand sanitizer after fishing, gardening, camping, or playing outdoors when your hands are likeliest to be dirty or greasy. You must wash your hands with lukewarm water, and soap for at least 20-30 seconds after such activities.

[bhandvalkar94]

Global Antibiotic Resistance Market to Grow at 4% CAGR during 2021-2029

When microbes evolve biological mechanisms that can protect them from elimination by antimicrobial, the danger of antimicrobial resistance (AMR) is visible. AMR are drug-resistant pathogens whose spread is a growing public health concern in many countries. The growth of resistant bacteria usually happens due to overuse of antibiotics, or due to their use being different from what has been prescribed. This renders antibiotics less effective or ineffective. It is believed that by 2050, AMR infections may cause 10 million deaths annually. Increase in hospitalizations and increasing use of antibiotics in COVID-19 treatment are expected to further exacerbate AMR. Hence, the market for antibiotic resistance research and medicines useful for treatment is expected accelerate in the near future.

Tuberculosis (TB) is one of the most dangerous infectious diseases from a single infectious agent and its virus has developed significant antibiotic resistance in the modern times. Multidrug-resistant TB (MDR-TB) is considered a global public health emergency by the World Health Organization. According to 2017 estimates, 465,000 cases of TB were estimated worldwide. 38% people were eligible for MDR/Rifampicin-resistant (RR)-TB. 57% of MDR/RR-TB cases received successful treatment. Mylan has also secured approval from Drugs Controller General of India (DCGI) for Pretomanid, which is useful for treatment for highly drug-resistant forms of tuberculosis. Johnson & Johnson has been in the business of developing and responsibly deploying innovative technologies and treatments to combat the growing threat of AMR on multiple fronts.

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The major factor driving the growth of global antibiotic resistance market is the growing prevalence of hospital-acquired infections. Antibiotic resistant bacteria can spread from person to person in the community. Implementing precautionary infection control procedures can minimize spread of such bacteria in hospitals. From person to person, usually this infection spreads from contact with either contaminated hands of hospital staff, or contaminated surfaces such as door handles, over-bed tables and call bells. Sometimes it also spreads due to contact with contaminated equipment that includes stethoscopes and blood pressure cuffs.

Strategic investments coupled with favorable initiatives by regulatory authorities showcases significant opportunities for the growth of global antibiotic resistance market over the period of next eight years. The Food and Drug Administration (FDA) of the United States of America (USA) and the Centers for Disease Control (CDC) in USA have launched several initiatives to help address antibiotic resistance. FDA is also encouraging new research into effective diagnostic tests, antibiotic regimens, and vaccines. Under qualified infectious disease product (QIDP) program, which is meant to encourage antibiotic development, FDA has also approved new and innovative antibiotics for resistant infections. Such antibiotics include Arikayce (amikacin liposome inhalation suspension), Baxdela (delafloxacin), Nuzyra (omadacycline), Pretomanid, Recarbrio (cilastatin, imipenem, & relebactam), Xerava (eravacycline), and Xepi (ozenoxacin).

The different variants of the coronoavirus has had severe impact on patients. Increased dosage of antibiotics are being prescribed to COVID patients who developed co-infections (bacterial with coronavirus). Increased investments into research and development initiatives towards adequate treatment of the same is anticipated to propel the growth of global antibiotic resistance market over the forecast period.

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 Key Findings of the Report:

·         The global antibiotic resistance market was valued at US$ 8417.36 Mn in 2020 growing at a CAGR of 4% over the forecast period (2021 – 2029).

·         The carbapenem-resistant enterobacteriaceae (CRE) category in the global antibiotic resistance market held the larger market share in 2020. Carbapenem-resistant enterobacteriaceae (CRE) are a family of bacteria that are very difficult to treat due to their highly resistant nature towards antibiotics. They have a reputation of adapting to different types of antibiotic treatments and develop resistance towards them.

·         The complicated urinary tract infections (cUTI) category in the global antibiotic resistance market held the larger share in 2020. Urinary tract infections (UTIs) are considered to be one of the most common types of infections. According to studies, at least one in two women and one in 10 men experience UTI in their life period.

·         Antifolates segment occupied the largest market share in the global antibiotic resistance market in 2020. Antifolate drugs are helpful in the treatment of communicable and infectious diseases such as malaria. Many bacteria and viruses that have developed antibiotic resistance spread diseases similar to malaria, such as dengue and other mosquito-borne diseases.

·         In 2020, North America dominated the global antibiotic resistance market. Availability of advanced medical sector, increasing prevalence of infectious diseases, presence of major market players, numerous drug launches in the market, and rising growth in the pharmaceutical sector amongst other factors have contributed towards the region’s highest share. Infectious Diseases Society of America (IDSA) has approved the use of many new drugs that are expected to offer successful treatment against bacteria and viruses that have developed antibiotic resistance.

·         Some of the major players operating in the global antibiotic resistance market are Allergan Pharma Co., GlaxoSmithKline PLC., Johnson & Johnson Services Inc., MELINTA THERAPEUTICS - THE ANTIBIOTICS COMPANY, Merck & Co. Inc., Mylan N.V., Nabriva Therapeutics PLC, Otsuka Novel Products GmbH, Pfizer Inc., and Sandoz AG amongst others.

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Global Antibiotic Resistance Market:

·         By Resistant Bacteria Type

o   Pseudomonas Aeruginosa

o   Clostridioides difficile (C. difficile)

o   Carbapenem-resistant Enterobacteriaceae (CRE)

o   Streptococcus pneumoniae (S. pneumoniae)

o   Acinetobacter

o   Vancomycin-resistant Enterococci (VRE)

o   Mycobacterium Tuberculosis (TB)

o   Neisseria gonorrhoeae (N. gonorrhoeae)

o   Others

 ·         By Disease Indication

o   Complicated Urinary Tract Infections (cUTI)

o   Complicated Intra-Abdominal Infections (cIAI)

o   Community-Acquired Bacterial Pneumonia (CABP)

o   Acute Skin and Skin Structure Infections (ABSSSI)

o   Multidrug-Resistant (MDR) and Pulmonary Extensively Drug Resistant (XDR) Tuberculosis (TB) (MDR-TB and XDR-TB)

o   Sepsis

o   Clostridium Difficile (C. difficile) Infections

o   Others

 ·         By Drug Class

o   Antimycobacterials

o   Fluoroquinolones

o   Oxazolidinones

o   Tetracyclines

o   Penicillins

o   Antifolates

o   Combination Treatment

o   Others

 ·         By Route of Administration

o   Oral

o   Topical

o   Intramuscular

o   Intravenous (IV)

 ·         By End Use

o   Home Care

o   Healthcare Facilities

o   Others

 ·         By Region

o   North America

§  U.S.

§  Canada

§  Mexico

§  Rest of North America

o   Europe

§  France

§  The UK

§  Spain

§  Germany

§  Italy

§  Nordic Countries

·         Denmark

·         Finland

·         Iceland

·         Sweden

·         Norway

§  Benelux Union

·         Belgium

·         The Netherlands

·         Luxembourg

§  Rest of Europe

o   Asia Pacific

§  China

§  Japan

§  India

§  New Zealand

§  Australia

§  South Korea

§  Southeast Asia

·         Indonesia

·         Thailand

·         Malaysia

·         Singapore

·         Rest of Southeast Asia

§  Rest of Asia Pacific

o   Middle East & Africa

§  Saudi Arabia

§  UAE

§  Egypt

§  Kuwait

§  South Africa

§  Rest of Middle East & Africa

o   Latin America

§  Brazil

§  Argentina

§  Rest of Latin America

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About Us: Absolute Markets Insights assists in providing accurate and latest trends related to consumer demand, consumer behavior, sales, and growth opportunities, for the better understanding of the market, thus helping in product designing, featuring, and demanding forecasts. Our experts provide you the end-products that can provide transparency, actionable data, cross-channel deployment program, performance, accurate testing capabilities and the ability to promote ongoing optimization. From the in-depth analysis and segregation, we serve our clients to fulfill their immediate as well as ongoing research requirements. Minute analysis impact large decisions and thereby the source of business intelligence (BI) plays an important role, which keeps us upgraded with current and upcoming market scenarios.

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[thehygienewarehouse]

Alcohol Gel Hand Sanitiser & COVID-19: The Guide To Prevent The Virus From Spreading

Ever since the outbreak of the Novel Coronavirus, the demand for hygiene products like hand sanitisers has increased massively throughout the world. Using alcohol-based hand sanitisers, in particular, has become part of the ‘new normal’ nowadays and the rising demand for it is an indication that it won’t slow down. Handwashing reduces the amount of all kinds of pesticides, germs, and heavy metals on hands. And knowing when to clean your hands and which method to use can help you prevent sickness.

Germs are everywhere. The WHO recommends washing hands with soap and water whenever possible as handwashing reduces the amount of all kinds of germs, bacteria and chemicals on hands. But, if soap and water aren’t available, using the best alcohol gel in Ireland can help you avoid getting sick and prevent spreading germs to others. Current guidance recommends frequent handwashing – be it with soap and water or sanitiser gel, for at least 20 seconds to avoid catching or spreading the Novel Coronavirus.

Here’s a detailed insight into washing your hands to protect yourself from COVID-19.

Coronavirus Driving The Demand For Hand Sanitiser

The recent outbreak of Novel coronavirus has played a crucial role in driving the dramatic expansion in demand for hand sanitisers and other hygiene products in Ireland and all over the world. Being a respiratory tract infection, COVID-19 primarily spreads from one person to another either through direct contact with an infected person or indirect contact with contaminated surfaces in the immediate environment.  

Abiding by good cleaning and hygiene practices is fundamental to prevent the spread of COVID-19. As a result, the demand for alcohol-based sanitisers has increased globally post the COVID-19 outbreak. This is mainly because alcohol gel sanitisers have proven to be extremely effective against the Novel Coronavirus. Hand sanitisers are a great thing to hand on hand, especially when you do not have access to soap and water.

How Effective Is Alcohol Gel In Ireland For Hand Washing?

When used correctly, hand sanitisers containing at least 60% alcohol can be very effective against microbes. Alcohol hand sanitiser gel can also be effective against the virus responsible for the novel coronavirus. While ethanol, the most common ingredient appears to be the most effective against viruses, propanols are highly effective against bacteria. For this, several hand sanitisers contain a combination of both ethanol and propanol.

When To Use Alcohol-Based Hand Sanitisers?

Even though alcohol hand sanitiser gel can quickly reduce the number of germs and pesticides in several situations, they must be used in the right situation. Here’s when to use hand sanitisers:

·       Before and after visiting someone in a nursing home or hospital, unless the person suffers from Clostridioides difficile (if so, use soap and water for washing hands)

·       If soap and water aren’t readily available, consider using an alcohol-based hand sanitiser that contains at least 60% alcohol

However, make sure you do not use hand sanitisers if your hands are greasy or visibly dirty.  

How To Use Hand Sanitiser?

The best way to use an alcohol gel in Ireland is to place a sufficient amount of gel into the palm and rub it all over. Make sure the amount is sufficient for covering all surfaces of hands and fingers. Rub the gel for at least 30 to 60 seconds since at times the gel can take 60 seconds to be effective. Keep in mind that hand sanitisers need to be rubbed in and left on both hands. Also, never wipe off or rinse the sanitiser before it is dry as it might not work well against germs.

Conclusion:

With COVID-19 cases growing throughout the world, proper handwashing should be every individual’s go-to strategy for prevention. And, washing your hands with a top-notch alcohol gel in Ireland can give you the best chance of preventing sickness. Make washing hands a priority and protect yourself!

[healthcarefoundationus]

Living with recurrent C. diff? 5 tips to enjoying the holidays

Just when we all thought it was still March, the holidays have crept up on us. Let’s face it, we could all use a little joy right now to brighten up our holidays. Although the holidays may look different this year, many of us are hoping to keep a few normal traditions. Whether it’s gathering safely with family or enjoying a special meal, if you’re suffering from a recurrent diarrheal condition like C. difficile infection, those things can be anything but normal. Here are 5 tips Dr. Paul Feuerstadt of the PACT Gastroenterology Center in Connecticut recommends to help people with C. diff enjoy the holiday season.

1) Try your best to decompress

The holidays come with their own set of stressors. Gathering for meals with loved ones shouldn’t be one of them. Feuerstadt explains that those living with recurrent C. diff often show greater signs of stress in general, and frequently when it comes to mealtime.

Many C. diff patients often suffer a range of increased emotions which can be further elevated during the holiday season. Whether it’s grief, anger, fear, depression or anxiety, remember the holidays are a time to be kind to one another, including yourself.1

Take some time for yourself. Each day take 10 minutes to relax. Close your eyes and try your best to clear your mind.

Find outlets to help manage your stress and anxiety, such as through yoga, listening to music, reading a good book or just by getting enough sleep (7-8 hours per night).1

Listen to your body. It will tell you when you may need to take a minute for yourself. If the feelings are more intense than you feel you can consistently handle, follow up with your healthcare provider.

2) Don’t try to do it all yourself

The holidays can be a busy time of year. From picking out gifts for loved ones, to decorating the house, those suffering from C. diff can feel overwhelmed easily.

Rather than trying to do everything this year, why not focus on a couple of fun holiday traditions you enjoy? Maybe your one big activity is family baking and you ask a family member to help you decorate cookies. Whatever it may be, remember you don’t need to do it all. Focus your attention on one or two holiday traditions so you’re able to enjoy them to the fullest.

3) Know what’s on the menu

Whether you’re the chef or guest at a holiday dinner, know what’s on the menu. If there are certain foods or ingredients you must avoid, let your host know.

Although no two people are alike, there are foods that C. diff patients should generally avoid, including dairy products with lactose, greasy foods and any foods that may cause bloating (e.g., broccoli, onions, beans).2

Knowing it’s never good to arrive at a holiday gathering empty-handed, consider bringing a dish that you know will keep your gut calm and that you can eat without repercussions.

Remember to consult your healthcare professional for more information on nutritional advice for foods that are best suited for your body type and C. diff infection.

4) Practice health and safety guidelines

Anyone living with recurrent C. diff knows how contagious it is. That’s why it’s important to ensure you maintain standard health and safety measures, such as frequent handwashing. When using the restroom, be sure to always wash your hands with soap and water before touching surfaces such as doorknobs. Please be aware that alcohol-based hand sanitizer will not kill C. diff spores.3,4

Although already top of mind for most, COVID-19 is still on the rise in many parts of the country. Proper handwashing, social distancing and wearing of face coverings is essential for everyone. Many people living with C. diff have already been practicing many of these universal hygiene measures before COVID-19 so this will be less of an adjustment.

COVID-19 has opened the doors to telehealth, making it even easier and more common for people with C. diff to connect with both their local medical providers but also experts across the country who might be able to help. If you feel that you are not well, you should feel free to utilize these modern tools to communicate with providers to get the proper care you need, when you need it.

5) Try a new tradition

2020 has been a year unlike any other. We’ve all had to reimagine the expectation of being “together” and perhaps this year is the time to try a new tradition — like a virtual meal with family and friends who are far away. If you’re a big football fan, you may consider a Zoom football watch party. Or how about a recipe and meal prep virtual gathering? It’s normal for people with C. diff to feel isolated, so try turning social distancing into an opportunity to be more connected without the stress of, “What if I need to get to the bathroom quickly?” Embrace technologies like Zoom to safely connect with loved ones and take this opportunity to spin this constraint into a positive.

Although the holidays this year will look a little different, consider these tips as a guide to safely connect with your loved ones and enjoy this special season. Above all, continue to talk to your healthcare provider about your symptoms, and potential treatments. There have been a number of important advancements in therapies for recurrent C. diff that may help people feel better and lead better lives.

About C. diff:

Clostridioides difficile (C. diff) is a type of bacteria that can cause diarrhea, fever, abdominal pain, nausea, colitis, and in more serious cases, shock and death. According to the CDC, it’s estimated to cause almost half a million illnesses in the United States each year.5 After initial C. diff infection, up to 35% of patients may experience symptoms again, also known as recurrent C. diff infection.6

To learn more about the power of the microbiome and if it can be unlocked to break the cycle of recurrent C. diff infection, visit http://www.powerofmicrobiome.com/ and on Twitter, follow @FerringUSA.

This piece is sponsored by Ferring Pharmaceuticals, a research-driven, specialty biopharmaceutical group committed to helping people around the world build families and live better lives.

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[nmadhavan]

Anuradha Chowdhary  was struggling and working alone on Candida auris. She is a Professor in the Department of Medical Mycology at Vallabhbhai Patel Chest Institute, University of Delhi, India. Now that the world is working on, why fungal infections shouldn’t be neglected.

Candida auris is a skin bug, a white overgrowth on the tongue or genitals. It can be easily treated with  an antifungal drug fluconazole, if not with amphotericin B, a second-line antifungal drug. Resistance to two classes of drugs is particularly concerning because India has limited access to the third option for antifungal treatment: echinocandins.

Current evidence suggests that SARS-CoV-2, the virus that causes COVID-19, patients to be routinely screened for the Candida auris, which involves collecting a skin swab, blood, or urine to test for the yeast’s DNA. After a patient tests positive for Candida auris, a medical procedure known as susceptibility testing is done to determine if any of the three classes of antifungal drugs can alleviate the infection. Because candidemia is a Candida fungal infection in the bloodstream, now may found in SARS-CoV-2 patients, spreading through the intensive care unit even though the hospital maintained extensive protocols for infection control.

Note: 1. Antimicrobial resistance as one of the top threats to global health. 2. Humanity is returning to a time when easily treatable infections—such as tuberculosis and gonorrhoea—can no longer be kept under control. 3. The global overuse of antimicrobial drugs on farm animals and in human medicine has been pegged as a cause for the emergence of superbugs. 4. The role climate change will play in the spread of fungal infections. 5. Fungal resistance could be as dangerous as antibiotic resistance, such as Clostridioides difficile or multidrug-resistant tuberculosis.

[cottoncare-laundry]

Contamination has been a global concern ever since COVID-19 pandemic has occurred.

We are all wary if there are parts of our home or commercial areas exposed to bio hazard. Recognizing the importance of professional assistance when it comes to disinfection is necessary as these disinfection specialists have the experience and knowledge of eliminating enemies that we can’t see.

However, most people are not aware of the differences of cleaning, sanitizing, and disinfecting and the level of protection it can offer to protect us from acquiring any illness. Below entails the differences among these three:

Cleaning – It is a method of removal of germs through the use of water and typical detergent. Some dangerous microorganisms can be physically eliminated through this cleaning method.

Sanitizing – Uses specialized agents that can help in reducing the number of germs lurking around the surfaces or objects. However, it cannot kill all dangerous virus and bacteria.

Disinfecting – Considers to effectively kill all germs to the extent that the chemical present in the disinfecting detergent can void the existence of any pathogens that can cause harm to the health of any person. Moreover, a quality disinfection service can combat and eliminate the following:

Corona Virus Parvo Virus Noro Virus Rhinovirus Influenza H1N1 Swine flu Staph Scabies Tuberculosis E. Coli Salmonella Listeria MRSA (Methicillin-resistant Staphylococcus aureus) C. Diff (Clostridioides difficile)

Why hire a professional disinfection specialist?

Among are the benefits of hiring a disinfection company:

1. It follows the process of cleaning, sanitizing and disinfecting of areas and may also include deodorization. 2. Uses safe and approved disinfecting detergents to ensure that eliminating of virus and germs follows safety procedures. 3. Uses top line technology to totally eradicate harmful viruses and bacteria in regardless of the location and guarantees 100% coverage of all surfaces and objects.

[cdifffoundation]

World Patient Safety Day 2020

World Patient Safety Day 2020

World Patient Safety Day, is an initiative by the World Health Organisation to raise awareness of the need to continuously improve patient safety, building on the foundations of a safer culture and safer systems.

World Patient Safety Day 2020 will bring together health workers, patients, families, caregivers, communities, health care leaders and policy-makers, all showing commitment to health…

[cdifffoundation]

Data Collected Finding Clostridioides difficile in COVID-19 Patients, Detroit, Michigan, USA

Data Collected Finding Clostridioides difficile in COVID-19 Patients, Detroit, Michigan, USA

Clostridioides difficile in COVID-19 Patients, Detroit, Michigan, USA, March–April 2020 Avnish Sandhu, Glenn Tillotson, Jordan Polistico, Hossein Salimnia, Mara Cranis, Judy Moshos, Lori Cullen, Lavina Jabbo, Lawrence Diebel, and Teena ChopraAuthor affiliations: Detroit Medical Center, Detroit, Michigan, USA (A. Sandhu, J. Polistico, H. Salimnia, M. Cranis, J. Moshos, L. Cullen, L. Jabbo, T.…

[cdifffoundation]

What Is SARS-CoV-2 and the Disease It Causes Named coronavirus disease 2019 or Better Known As COVID-19

      What is Coronavirus?

The virus has been named “SARS-CoV-2” and the disease it causes has been named “COVID-19.”

Coronaviruses are a large family of viruses that may cause respiratory illnesses in humans ranging from common colds to more severe conditions such as Severe Acute Respiratory Syndrome (SARS) and Middle Eastern Respiratory Syndrome (MERS).

‘Novel coronavirus’ is a new, previously…

[cdifffoundation]

The Food and Drug Administration (FDA) Informs Health Care Providers and Patients of the Potential Risk of Transmission of SARS-CoV-2 Virus and COVID-19 By the Use of Fecal Microbiota for Transplantation (FMT)

The global public health community is responding to a rapidly evolving pandemic of respiratory disease caused by a novel coronavirus that was first detected in China.

  The virus has been named “SARS-CoV-2” and the disease it causes has been named “COVID-19.”

The Food and Drug Administration (FDA) is informing health care providers and patients of the potential risk of transmission of SARS-CoV-2…