#Protac

[eurofinsadvinus]

Excited to share an example of our expertise in designing skills to create novel analogues and scaffolds for PROTAC programs. To speak with our team, write to us at bd@advinus.com

Follow us on for more updates.

[cdmoservices]

[johniac]

SciTech Chronicles. . . . . . . . .April 19th, 2025

[expopeak]

Discovery on Target 2024: Your Roadmap to Breakthrough Therapies

[attackcopterblog]

STREAMLIGHT ANNOUNCES THE PROTAC HL 6 FLASHLIGHT

Streamlight has announced their latest in illumination with the new ProTac HL 6 flashlight. Streamlight states “Streamlight® Inc., a leading provider of high-performance lighting and weapon light/laser sighting devices, introduced the ProTac HL® 6, the newest and brightest addition to the ProTac® series of tactical lights. Delivering up to 5,300 lumens and an extraordinary beam reach, the…

[technoclubstar]

EMF Protection with Defense Bracelet Deliverable

A Shield of Style: My Experience with the Defence Bracelet

In today's tech-driven world, we're constantly surrounded by electromagnetic fields (EMFs) emitted by our phones, laptops, and even household appliances. While the science on the long-term effects of EMF exposure is still evolving, concerns about potential health risks are on the rise. This is why I decided to try the Defence Bracelet, a product designed to offer protection from these invisible waves.

Advanced Technology, Stylish Design

The Defence Bracelet boasts a sleek and stylish design that complements any outfit. It's more than just a protective accessory; it's a conversation starter. The materials feel high-quality and comfortable against the skin. I opted for the classic black band, but the bracelet comes in a variety of colours and styles to suit individual tastes.

Beyond aesthetics, the Defence Bracelet incorporates advanced technology to create a protective shield. The details on the exact workings are proprietary, but the brand claims the bracelet utilizes a blend of materials and potentially specific frequencies to neutralize EMF waves. While I can't speak to the specific scientific mechanisms, the focus on innovative materials is reassuring.

Improved Wellbeing: More Than Just EMF Protection

While EMF protection was the primary reason I tried the Defence Bracelet, I've noticed some unexpected benefits. Since wearing it consistently, I've experienced a noticeable improvement in my sleep quality. I fall asleep faster and wake up feeling more refreshed. Additionally, I seem to have more sustained energy levels throughout the day. Whether this is a direct result of the bracelet or a placebo effect, I'm happy with the outcome.

It's important to note that the Defence Bracelet doesn't claim to be a cure-all. It's a tool for proactive wellness alongside a healthy lifestyle. However, the combination of improved sleep and increased energy has certainly had a positive impact on my overall well-being.

Peace of Mind in a Digital Age

Perhaps the greatest benefit of the Defence Bracelet is the peace of mind it offers. Knowing I'm taking a proactive step to mitigate potential EMF risks allows me to embrace technology without unnecessary worry. This is especially important as our reliance on electronic devices continues to grow.

The Defence Bracelet is a small investment that can have a big impact on your well-being. It's stylish, comfortable, and – based on my experience – offers a range of benefits beyond just EMF protection. Whether you're concerned about the potential health effects of EMFs or simply looking for ways to improve your sleep and energy levels, the Defence Bracelet is definitely worth considering.

[recoiloperated]

You don't need to EDC an entire toolbox, but the things that I find myself reaching for essentially constantly in my EDC is my flashlight, my pen, and my knife.

So, go out and get yourself a compact pocket light. A pen that's durable enough to carry but cheap enough to lose, (I am personally a fan of the pokka brand folding pens) and a decent folding knife.

If you are unfortunate enough to have girl pockets, My go-to light is going to be the streamlight microstream. It's tiny.

If you have bigger pockets, the macrostream/Protac 1L-1AA is a great choice. The 1L- 1aa is a triple fuel flashlight, accepting standard AA batteries, CR123, and 14500's.

Honestly, even though I have carried a 21700 light in the past, I wouldn't suggest going anything larger than an 18650 light. And I would probably suggest going smaller than that even.

[moshieee]

What does M.o.s.h.i.e. Stand for??

You are attempting to access a restricted file

Activating TFOV safety protacal . . .

Enter authority level and I.D number

_ _ _ _ _ _ _ _ _ _ _ _ _

[eurofinsadvinus]

We are happy to announce our participation at the upcoming 4th Annual TPD (Targeted Protein Degradation) Europe. Our team will be at the conference from the 19-21 March 2024 in London, UK. We are eager to engage with fellow industry leaders, scientists, and experts at this prestigious event. Join us as we delve into the latest advancements and strategies shaping the future of targeted protein degradation. Connect with our team and explore how Eurofins Advinus can support your journey towards groundbreaking therapies. See you there! To schedule a meeting, email us at bd@advinus.com

[cdmoservices]

Advantages of PROTACs over traditional drugs

(PROTAC) can overcome most of the limitations of small molecule inhibitors, and they offer several advantages of the traditional concepts of drug discovery by targeted protein degradation.

[scientificchina]

Scientists from prestigious institutions in Beijing, including Tsinghua University and Beijing Normal University, have developed a pioneering method to selectively degrade multimeric proteins. Published in Cell, the study introduces TRIM21-based molecular glues and PROTACs as advanced tools for tackling diseases such as cancer, neurodegeneration, and autoimmunity.

[ptpgunmedia]

F4 Defense F4-15 For Sale

I am cycling out part of my collection and today I am selling my home defense weapon that I have had the last four years.

F4 Defense is a local (but world recognized) veteran owned firearms manufacturer based out of Leonardtown, Maryland. These firearms have been reviewed by the likes of Garand Thumb, Mrgunsngear, and Colion Noir.

Check out this product on their website CLICK HERE

This is a solidly built handgun and is on the Maryland Handgun Roster. This handgun is paired with the Magpul MBUIS Pro (front and rear), Streamlight ProTac Rail Mount HL-X Light/Laser with pressure pad, and Sig Romeo5 red dot.

Highly portable, the F4 PDW performs flawlessly as a compact, ergonomic personal defense weapon. The F4 PDW provides self-defense minded civilians, a compact and reliable CQB weapon chambered in 5.56 or .300 Blackout.  The F4 PDW runs effortlessly with or without a suppressor.

Receivers: Precision CNC Machined F4-15 Matched Billet 7075-T6

Controls: Full Ambi Bolt Catch and Mag Release

Barrel: 7.5 or 8″(300BO)

Caliber: .223 Wylde or .300 Blackout

Fire Control Group: TriggerTech Competitive AR Primary Trigger, 2-Stage: 3.5lb

Handguard: Adaptive Rail System (ARS) 9” or 6.5″

Gas System: Pistol

Charging Handle:  Radian Raptor (AMBI)

Selector: Radian Talon Short-throw Ambi Selector

Bolt Catch – Billet Titanium – DLC Coated

BCG: Black Nitride BCG – MPI Bolt (158 Carpenter Steel)

Muzzle Device: Linear Comp

Stock: SB Tactical Pistol Brace SBA3 (The PDW brace is pictured but is not longer included)

Overall Length: 23.5″

Weight: 5.79lbs

Finish: Type III Class II Anodized Black

This sale will not come with magazines. Asking price is $2200. Ammunition available for additional costs. All state and federal laws will be followed with this sale, Maryland HQL needed for a Maryland buyer. You can use an FFL of your choosing. Free feel to email me at ryan@ptpgun.com

I will delete this blog once it is sold. If you are reading this- its still available.

Original Sources: https://www.ptpgun.com/post/f4-defense-f4-15-for-sale-1

[kyledefoor]

Essentials -

@staccato2011 CS, @tenicorusa Certum

@harley_elmore Rat

@sangin.instruments Neptune

@streamlightinc Protac 1L

@ridgewallet

@prometheusdesignwerx mats

…..sunglasses unreleased but coming soon

#defoor #defoorproformanceshooting #kd4