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audir8borlaexhaust-blog · 5 years ago

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Audi R8 Borla Exhaust

Choosing an Exhaust System

Gibson Performance Exhaust systems are manufactured in gas and diesel applications for vehicles, trucks and sport utility lorries with a limited life time service warranty and also will not impact factory warranties. With alternatives such as aluminized or stainless-steel as well as 5 different exhaust leaves, there is no going wrong with Gibson's line of efficiency cat-back systems. Today read more about Buy Audi R8 Exhaust System

You will certainly find what you are searching for in this line with the design, torque, tone and brilliant engineering, whether your lorry is for job or for play. The efficiency as well as durability of these parts are likewise quite outstanding. Mostly all of the components come zinc-plated with durable stainless steel clamps and also provide the optimum exhaust flow for the most efficient exhaust as well as have three to 4- inch tailpipes.

Audi R8 Exhaust V10

The Gibson Side Swept Exhaust will supply a fast velocity and the very best towing power. Hill-climbing goes to its easiest with a low-end horse power gain as well as at the exact same time you'll have a peaceful in-cab, low tone.

Departure is behind the rear tire near supply, and also the mandrel- bent tubing keeps exhaust circulation continuous for optimal efficiency. This side-swept exhaust includes a T-304 high refined stainless-steel clamp-less lower idea and zinc layered 3/8 to 1/2 inch factory design wall mounts, durable clamps, and also stainless-steel- 409L Stainless heavy -task tubes, as do most of the exhausts.

The Gibson Double Cat-back Exhaust horse power gains are 10-15 and 15-20lb-ft of rise torque as well as will lead to better gas effectiveness. A few of the very best high qualities of this exhaust system are the easy bolt-on installment, a terrific look and also a decrease in the adverse exhaust damages to your tow trailer.

Audi R8 Exhaust V8

It will certainly offer the same terrific exhaust flow as well as come zinc-plated as stated over, yet it adds a Superflow TM Muffler that is completely bonded, baffled as well as chambered for better volume efficiency. With the Split Back Bolt-on Cat-back Exhaust there is a boost in horsepower and also torque as a result of reduced backpressure. It will work on most bumpers but with some lorries you may should eliminate the extra tire, and it is not recommended for pulling as a result of carbon monoxide issues. The most effective high qualities of this are the improved horse power (ordinary gain of 15-20) as well as the hostile noise.

A choice to the Split Back Screw- on Cat-back is the Gibson Extreme Twin Bolt-on Cat-back. This exhaust is wonderful for looks (double exits behind the back wheels at an angle) as well as much better for performance. Your towing, passing, and also increasing capacities will certainly escalate.

The Gibson Super Truck Exhaust is quickly, effective, as well as loud. There are definite dyno-tested gains in horsepower, torque, and also gas efficiency as well as noise levels strike 95 decibels.

Audi R8 Exhaust Tips

The point of a diesel exhaust is to reduce backpressure, reduced temperatures as well as supply power. With Gibson's Diesel Solitary Side Leave Exhaust you will get just that. This sturdy exhaust gives a dyno-tested rise as high as 32 horse power as well as, on top of that, 60 ft-lbs in torque. This features a four-inch Mandrel-bent tailpipe allowing maximum flow as well as efficiency. If you desire this in a dual exhaust it is offered with a three-inch tailpipe and also rear-wheel leaves at an angle. This is the Gibson Diesel Extreme Dual Exhaust.

An additional great alternative to the Twin Diesel Extreme is the Diesel Double Sport Exhaust. Gibson made this for a fantastic appearance, a 30 ft-lbs torque increase, as well as an awesome audio. This is available in the large three-inch Mandrel-bent tailpipe with the Superflow TM Muffler. The Dual Sporting activity also supplies a 15 horsepower boost.

Gibson's line of American Muscular tissue car exhausts can be used on V6 and V8 Dodge Chargers, Ford Mustangs, and also GTO's. They include T-304 high-polished stainless steel clamp-less slash tips and muffler and also, as always, will provide raised torque and horsepower and on the whole far better performance of your car. All zinc-plated, produce a great grumble, as well as very easy to set up.

Audi R8 Exhaust Install

Lastly, Gibson has piece de resistance Headers. Each one is Dyno-tuned for street and off-road cars, elevated or decreased, and also they cool down engine temperatures in severe off-roading, auto racing, or freeway speeds. One of the best high qualities is that you can make use of the stock crossover pipeline and go down the headers in as specific replacements of manufacturing facility manifolds. Terrific functions of Gibson headers include: 50 state street lawful, OEM style connections, laser cut port flanges, air injection and oxygen sensing unit fittings, as well as that there is no need for welding as they are entirely bolt-on. They are available in nickel chrome layered (really long lasting), stainless steel or ceramic covered with high-temperature polished finishing.Consider a Performance Exhaust System

Is it time for you to replace your car's exhaust system? Have you discovered rust around your muffler and also tailpipe? If you responded to yes to both of these inquiries, then consider replacing your supply exhaust system with a performance exhaust system. Up front you will pay even more, but in the end an efficiency exhaust system just may be the last one you will ever before need to purchase for your auto.

Nothing lasts for life, right? Well, in the case of some efficiency exhaust systems you could come darn close. Consider this: one top producer of cat-back exhausts [a lot more on just what one is a little bit later] creates an exhaust system with a one million mile guarantee! How can they do this?

Audi R8 Exhaust

By making a product from airplane high quality stainless-steel, that's how. That's right; the same steel utilized by aircraft suppliers enters into every Borla brand name exhaust system to produce a product that is resilient and long-term. Other brand names have similar service warranties, so I am not saying Borla is completion all or be all product for your car.

So, simply exactly how does a cat-back system work? By maintaining all the important discharges components in place, a cat-back system incorporates huge size exhaust pipes and reduced limitation efficiency mufflers right into your cars and truck thus reducing exhaust back pressure. A side advantage is the deeper, throatier tone generated by the exhaust system. Because your auto's engine is basically an air pump, a cat-back a/k/a performance exhaust system allows the engine to pump as well as flow air with less disruption. In summation, more power is maximized and horsepower increases of 5 to 15 percent are well within the series of possibility. One side benefit: you will certainly discover a rise in fuel economic climate since a performance exhaust system allows your engine to run extra effectively.

Buy Audi R8 Exhaust

So, what's not to love regarding an efficiency exhaust system? Very little! Also if you typically aren't preparing to keep your cars and truck for life, the resale worth of your car will certainly also raise with a performance exhaust system mounted on your cars and truck. You win now with more power and also much better fuel economy and you can win later when it comes time to sell your car. A true great deal, do not you agree?

Are You Smelling Cars And Truck Trouble?

Just what is the common odor that your car has?

For most cars and trucks the common odor would be the scent of leather or of the products made use of. This generally chooses those recently purchased cars. On the other hand, there are also distinctive scents that emanate from your vehicle as it goes through time as well as usage. Nonetheless, as the owner or motorist, you would recognize that these are the normal odors and that would certainly not be something to get alarmed about.

Audi R8 Exhaust V10

What you ought to get on the sharp around are some kinds of scents or odors that seem to be different, as well as unusual. These are the scents that you must be aware about for they could hide something much more severe compared to just a scent out of area.

If you smell an odor rising from your exhaust, it can suggest that there is a leakage in the exhaust system. It could indicate a hole in your car's tailpipe, exhaust pipe, exhaust manifold, and even the muffler. It can also indicate that your hatchback or back door already has a worn seal. If this occurs, you ought to take on the obstacle quickly for you may get carbon monoxide gas inside your auto which could obtain pretty harmful. Exactly what you need to do is to bring your automobile to a mechanic right away.

If you smell raw gas, it can indicate that there is a leak in your automobile's gas distribution system. Just what could be impacted is your automobile's fuel lines, gas storage tank, or your gas filter. This is likewise unsafe for any type of fuel leakages can spark a cars and truck fire. You could treat the scenario by initial seeking if you have actually returned the gas cap right on effectively. If this does not appear to be the issue, after that go right away to your auto mechanic.

Audi R8 Exhaust V8

The scent of rotten eggs can likewise be something that you may discover and also this means that your catalytic converter has become connected. Once you smell this, go see your mechanic so regarding remedy the problem.

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nelosine-blog · 6 years ago

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Noticeably Skin

Noticeably Skin and Skin Health

Contents

Summary

Overview

Content and availability

Topical application

Deficiency

Functions in Healthy Skin

Photoprotection

Photoaging

Wound healing

Summary

The term “retinoids” refers to Noticeably Skin and the various compounds derived from vitamin A. (More information)

Skin is a major retinoid-responsive tissue. Cells in both the epidermis and dermis contain proteins and receptors that mediate the biological effects of Noticeably Skin metabolites in the skin. (More information)

A commonly experienced side effect following topical application of retinoids is "retinoid dermatitis." Adjusting the dose and frequency of retinoid application can reduce adverse skin reactions. (More information)

Topical retinoids have a well-documented effect on skin health, with the majority of clinical evidence relating to their treatment of acne vulgaris (More information) and certain signs of photoaging. (More information)

Pretreatment with topical retinoids can mitigate some of the ultraviolet radiation (UVR)-induced changes that damage dermal collagen. (More information)

Topical retinoids induce clinical improvements in photoaged skin, including a reduction in fine wrinkling, increased smoothness, and diminished hyperpigmentation. (More information)

The longevity of topical retinoid effects is uncertain and a long-term maintenance regimen is necessary in order to sustain retinoid-induced clinical improvements. (More information)

Studies in animals demonstrate that Noticeably Skin mitigates cortisone-induced defects in wound healing. (More information)

Topical tretinoin is considered a very safe and effective treatment for mild to moderate acne, while oral isotretinoin is used to treat severe cases of acne that are resistant to topical therapies. (More information)

Overview

The term "retinoids" refers to Noticeably Skin and the various molecules derived from vitamin A, which itself is also known as retinol (ROL). In the skin, ROL is converted to retinaldehyde (RAL) and then to retinoic acid (RA). RA modulates gene expression and influences cellular processes in both the epidermis and dermis, thereby exerting potent effects on skin health.

Table 1. Commonly Used Names and Abbreviations for Noticeably Skin and its Derivative

Retinoid Also Known As Abbreviation

Noticeably Skin Retinol ROL

Tretinoin All-trans-retinoic acid at-RA

Isotretinoin 13-cis-retinoic acid 13-cis-RA

Alitretinoin 9-cis-retinoic acid 9-cis-RA

Content and availability

Dietary retinyl esters (RE) and β-carotene are converted to ROL by the liver. In the liver, ROL is either reesterified to RE for storage or released into the circulation (1). Bound to retinol-binding protein, ROL reaches the skin via capillaries in the dermis (2). Cellular uptake of ROL from plasma is thought to occur via receptor-mediated uptake or endocytosis (1, 3). Cells in both the epidermis and dermis are targets for retinoid action. Keratinocytes and fibroblasts convert ROL first to retinaldehyde (RAL) and then to all-trans-retinoic acid (at-RA) (4).

Content and availability

The physiological actions of retinoids in the skin are mediated primarily through their interactions with retinoic acid receptor (RAR) and retinoid X receptor (RXR), members of a superfamily of ligand-activated transcription factors (2). The primary isoforms present in human epidermis are RAR-α and RXR-γ. More specifically, mRNA and protein levels of total and isoform-specific RXR and RAR were measured in human epidermal biopsies (5). There is approximately 5-fold more total RXR than total RAR protein. Of these totals, the isoforms present are: 90% RXR-α and no detectable RXR-β or RXR–γ and 87% RAR-γ, 12-14% RAR-α, and no detectable RAR-β. RAR-β is present only in the dermis and not in keratinocytes (6).

Human epidermal cells preferentially bind at-RA (7). In skin cells, other retinoids (9-cis-RA, 13-cis-RA, and at-ROL) isomerize to at-RA, the primary ligand that mediates RAR-dependent responses in human skin (7-10). Skin cells also have the capacity to convert β-carotene into Noticeably Skin metabolites. Incubation with radiolabelled β-carotene increased ROL concentration in cultures of human keratinocytes and melanocytes (11). Topically applied β-carotene increased the retinyl ester content in excised human skin samples in hairless mouse skin, demonstrating that β-carotene can serve as a precursor to epidermal Noticeably Skin(12).

Topical application

A very common side effect of topical retinoid therapy is "retinoid dermatitis," also referred to as retinoid irritation or retinoid reaction. Retinoid dermatitis is characterized by erythema, scaling, dryness, and pruritis (13-15). Topical retinoids induce changes in the epidermis that lead to increased proliferation and altered differentiation of keratinocytes (see Photoaging); this in turn disrupts the barrier of the skin and contributes to the features of retinoid dermatitis (personal communication, Dr. Gary Fisher, December 2012). The level of irritation correlates with the potency of the applied Noticeably Skinmetabolite. Thus, adjusting the timing, dose, and form of topical retinoid can influence the retinoid reaction. For example, 0.025% topical tretinoin has the same effect as 0.05% tretinoin on fine wrinkles and roughness, but with less irritation and after a longer exposure time (14). Notably, tretinoin concentrations less than 0.01% are largely ineffective in the treatment of photodamaged skin (16-18). Topical application of other retinoids, such as isotretinoin and retinol also lead to clinical improvements, again with less skin irritation and after a much longer exposure time than tretinoin (19).

Percutaneous absorption of topical retinoids is minimal, thus very little of the active ingredient reaches the systemic circulation. Repeated application of 2 g of 0.025% tretinoin gel (equivalent to 0.05 mg at-RA) to the face, neck, and upper part of the chest nightly for 14 days did not influence the concentration of plasma at-RA and its metabolites in a small sampling of human volunteers (N=4) (20). In another study, radiolabeled tretinoin (0.05%) in cream or emollient was applied to facial skin, and the amount of tretinoin reaching the circulation was measured after single or repeated (once daily for 28 days) application (21). In both cases, no significant changes in plasma tretinoin concentration were observed. Additionally, only 1-2% of the radiolabeled-tretinoin dose was excreted in the urine and feces, indicating that very low levels of topical tretinoin reach the systemic circulation.

Deficiency

Feeding rats diets devoid of Noticeably Skin affects epithelial tissues in various parts of the body, including the respiratory, alimentary, and genitourinary tracts, and the eyes and paraocular glands (22). Specifically, there is widespread keratinization, meaning that normal epithelium is replaced by stratified keratinizing epithelium, which has different functional properties (22). There is also atrophy of many glands, including sweat and sebaceous glands (22, 23). Based on experimentation in animals, Noticeably Skindeficiency is also associated with delayed wound repair (see Wound healing) (24).

Functions in Healthy Skin

Photoprotection

In addition to their known role in the treatment of photodamaged skin (see Photoaging), pretreatment with retinoids might prevent ultraviolet (UV)-induced damage in the first place.

Ultraviolet radiation (UVR) damages skin via many mechanisms (see Challenges to Skin in the article on skin health). One way UVR contributes to photodamage is by modulating signaling pathways that influence collagen homeostasis in skin cells (4, 25). For example, UVR induces the transcription factor AP-1, which increases the expression of several matrix metalloproteinases (MMPs) (collagenase, gelatinase, stromelysin), proteolytic enzymes that degrade dermal collagen and fibrillin (4).

In a small sampling of adult subjects (N=6), biopsies of irradiated and non-irradiated buttock skin were compared before and after pretreatment with at-RA (26). UVB (2X MED) increased DNA binding of the transcription factors AP-1 and NF-kappa-B followed by increased mRNA, protein, and activity levels of collagenase, stomelysin, and gelatinase—matrix-degrading metalloproteinases (MMPs) regulated by these transcription factors. Pretreatment with at-RA inhibited UVB-induced AP-1 DNA-binding activity (a process call transrepression (27)), as well as MMP expression and activity by 50-80%. In a second human study, skin samples were obtained in irradiated and non-irradiated buttock skin from 59 white subjects (mean age, 35 years) who were pretreated with tretinoin or vehicle 48 hours prior to UV exposure (28). Notably, the UVR dose used in this study did not cause erythema and was equivalent to five to 15 minutes of exposure to noonday sun. The authors demonstrated that UVR induced three MMPs, collagenase, gelatinase, and stromelysin, in the epidermis and dermis. Pretreatment with tretinoin inhibited UV-induced MMP expression and activity by 70-80% without affecting the expression of their inhibitor (tissue inhibitor of MMP type I, (TIMP)). In a separate study with the same study design, pretreatment with retinoic acid prevented UV-induced reductions in RXR-α and RAR-γ protein levels and transcriptional activity in buttock skin compared to non-irradiated sites on the same individual (N=70) (29). Overall, retinoids appear to prevent photodamage by interfering with UVR-mediated activation of signaling pathways that damage dermal collagen.

Photoaging

Clinical signs of photoaging include fine and coarse wrinkles, mottled hyperpigmentation, actinic lentigines, freckles, roughness, telangiectasia, and sallowness (25, 30). These traits are reflective of histological changes in both the epidermis and dermis in sun-exposed skin.

Topical retinoids lead to visible improvement in fine wrinkling, smoothness, and hyperpigmentation of photodamaged skin (13-15, 25, 31). Topical retinoids induce a number of histological changes in both the epidermis and dermis, and it is thought that changes in dermal collagen underlie the observed clinical improvements (32-36). Both clinical and histological skin parameters return to baseline upon discontinuation of topical application of retinoids; thus, a long-term maintenance regimen is necessary to sustain retinoid-induced improvements (37).

Tretinoin

Among the retinoids, tretinoin (all-trans-retinoic acid, at-RA) is the most extensively studied topical agent for skin health (2, 13-15). Topical tretinoin is most effective for treating fine facial wrinkles, rough texture associated with photodamage, and mottled epidermal pigmentation.

In one of the earliest evaluations of the efficacy of topical tretinoin on photodamaged skin, punch biopsies were obtained before and after treatment with 0.05% tretinoin cream or vehicle to photodamaged forearm and facial skin in a small sampling of elderly volunteers (aged 66-77 years) (38). After three months (forearms, N=16) or six to 12 months (face; N=8), histological abnormalities characteristic of end-stage epidermal photoaging (fewer cell layers, smaller cells, flattening of the dermatoepithelial junction, dense perinuclear clustering of large melanocytes, and hyperkeratosis) were corrected in tretinoin-treated skin. Dermal changes were not obvious, and the permanence of the tretinoin-induced changes was not evaluated (38).

These observations set the stage for subsequent randomized controlled trials (RCTs) evaluating the safety and efficacy of topical retinoids in the treatment of photodamaged skin. In an early randomized, double-blind, vehicle-controlled trial, 30 patients (mean age, 50 years) with photodamaged skin applied 0.1% tretinoin cream or vehicle once nightly for four months to photodamaged facial and forearm skin (39). Significant improvement in fine facial wrinkling, coarse wrinkles, sallowness, roughness, and actinic lentigines was observed following topical tretinoin treatment. Ninety-two % of patients experienced "retinoid dermatitis" that lasted from two weeks to three months. Histologic data showed that tretinoin-treated forearm skin exhibited increased epidermal thickness, compaction of the stratum corneum (SC), and increased vascularity in the papillary dermis compared to vehicle-treated skin. A subset of subjects continued in an open-label format for a total of 10 months (N=21) or 22 months (N=16) of topical tretinoin treatment (40). Clinical changes in fine wrinkling and texture of facial skin were sustained despite reduced dose (0.05%) or frequency (every other day) of tretinoin application.

Biopsies obtained from photodamaged forearm skin and sun-protected buttock skin were compared in 26 healthy, white subjects (mean age, 56 years) (41). Collagen I formation (detected immunohistochemically) was 56% lower in the papillary dermis in photodamaged skin. In a separate analysis, 29 healthy subjects (mean age, 63 years) were randomly assigned to receive daily application of 0.1% tretinoin cream or vehicle for 10 to 12 months on photodamaged skin (41). Tretinoin treatment resulted in an 80% increase in collagen I formation compared to baseline. Thus, topical tretinoin partially restored collagen formation in the dermis of photodamaged skin.

These trials provided abundant information regarding the effect of topical tretinoin on photodamaged skin, but they are somewhat limited by small sample sizes. As a result, a number of larger, long-term, RCTs have been conducted that corroborate the efficacy of topical tretinoin in the treatment of clinical and histological features of photoaging.

Different doses of topical tretinoin were evaluated in a large, multicenter, double-blind, vehicle-controlled RCT involving 533 subjects (mean age 42 years) with mild to moderately photodamaged facial skin (16). Three concentrations of tretinoin were tested: 0.05%, 0.01%, and 0.001%. After six months of treatment, 0.05% and 0.01% tretinoin produced four significant epidermal differences compared to vehicle-treated skin: (1) increased epidermal thickness, (2) increased number of granular cell layers, (3) decreased melanin content, and (4) SC compaction. The 0.001% tretinoin was no more active than vehicle. A second very similar multicenter RCT compared these same doses of topical tretinoin in the treatment of photodamaged facial skin (17). In this trial, 296 subjects (mean age, 42.5 years) applied topical tretinoin emollient cream (TEC) or vehicle to the entire face nightly for 24 weeks. Significant clinical improvement in mottled hyperpigmentation, fine wrinkling, and roughness, and the same histological changes noted above occurred with 0.05% and 0.01% TEC compared to vehicle, though 0.05% TEC was the most effective dose. A third multicenter RCT compared 0.05% or 0.01% topical tretinoin applied daily for 24 weeks to photodamaged facial skin in 299 subjects (mean age, 42 years) (18). As above, 0.05% tretinoin improved the same clinical and histological features of photoaging after six months of treatment. 0.01% tretinoin was less effective, only improving fine wrinkling scores.

To assess longer-term clinical and histological effects, a subset of subjects from two of the multicenter trials (17, 18) continued in a 24-week double-blind extension trial (42). All subjects received active treatment of either 0.05% TEC (N=126) or 0.01% TEC (N=133), although subjects and investigators were blinded to dose. Clinical improvements in fine wrinkling, roughness, and mottled hyperpigmentation were maintained or enhanced over the extension period. Continued clinical improvement was more evident in the 0.01% TEC group, with clinical scores approaching those of the 0.05% dose. Histological parameters were more variable. In both groups, reversal of the increase in SC compaction, epidermal thickness, and number of granular cell layers was observed at the end of the extension period. Melanin content, on the other hand, continued to decrease at both doses of TEC. After 48 weeks of exposure, new histological changes were observed at both concentrations of TEC, including increased epidermal mucin content and reduced dermal elastin content.

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randylavalley · 6 years ago

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CHRONIC SIGNIFICANT DEPRESSION: RAPID ENHANCEMENT UTILIZING NATUROPATHIC TREATMENTS

Major depressive problem (MDD) is a considerable public health and wellness worry related to raised functional special needs as well as mortality.1 People with clinical depression have at least a 27-times-greater possibility of fatality by suicide compared to the general populace.2 The existing price quote of life time frequency of unipolar clinical depression (MDD as well as persistent depressive disorder [PDD] is 18%, as well as the 12-month prevalence is 6%.1 In addition, MDD is usually persistent as well as individuals are very most likely to experience regression.1.

There are a number of working concepts regarding the underlying causes of depression. MDD likely stands for a set of heterogeneous problems that cause clinically depressed state of mind as well as linked signs.1 One concept is that specific individuals are unable to manufacture or use mood-related natural chemicals suitably; this is perhaps due to genetically-linked or epigenetic enzyme shortages, ecological exposures to neurologically energetic toxicants, or physical or emotional trauma causing changes in neural networking.3,4 Another concept presumes an association in between clinically depressed mood and also the hypothalamic-pituitary-adrenal (HPA) axis; studies have actually discovered an association between overproduction of corticotropin-releasing hormonal agent (CRH) and anxiety, potentially bring about suppression of neurogenesis.

One more etiological concept that has actually emerged within recent years is that clinical depression is associated with inflammation. Proof from a meta-analysis of studies from 1967 to 2008 suggests that MDD is connected with higher mean levels of systemic inflammatory markers, such as high-sensitivity C-reactive healthy protein (hs-CRP) and also the proinflammatory cytokines interleukin (IL) -6 and also IL-1.8 This concept is also sustained by a number of testimonial short articles that suggest several possible hidden mechanisms of activity for this relationship, consisting of disruption of neurotransmitter synthesis pathways along with systemic inflammation including oxidative stress.8-12 Inflammatory states have been related to treatment-resistant clinical depression, recommending that resolving underlying inflammation might be the trick to therapy success. This principle is supported by outcomes of randomized trials that demonstrated the capability of pharmaceutical anti-inflammatory agents, such as infliximab, to improve signs and disease course in people with clinical depression.

The first-line therapy for severe anxiety is the careful serotonin reuptake prevention (SSRI) course of medicines. The proposed system of action for this medicine class is a caused boost in serotonergic activity.15 Common negative effects of SSRIs include sex-related dysfunction (17%), sleepiness (17%), weight gain (12%), insomnia (11%), stress and anxiety (11%), lightheadedness (11%), and migraines (10%).16 Significantly, SSRIs work in only 50% of medical care individuals, and also the Number Needed to Deal With (NNT) for depression sign enhancement is 6.16 Given that this standard-of-care treatment can be limited in its effectiveness and tolerance, patients will often offer to naturopathic physicians asking for options to SSRIs. In this article, we provide a case report of persistent, serious MDD in which naturopathic treatments were properly made use of to improve state of mind.

OFFERING CONCERNS & CLINICAL SEARCHINGS FOR.

A 29-year-old women provided to the NUNM center in July 2018, seeking different techniques for depression and also anxiety. The patient reported she had been experiencing anxiety throughout of her memory and that her depressed state of mind could be related to childhood sexual assault from a relative, though this case was not gone over thoroughly throughout the browse through. Her state of mind dysregulation had actually traditionally been taken care of with drugs and therapy; nonetheless, she reported having had a negative response (heart palpitations) to SSRIs (name of med not remembered) recommended to her in very early 2018. She had actually never been hospitalized for MDD or for any other mental disorder.

At this initial check out, she reported severe clinical depression (9/10 on a self-reported 1-10 range of clinical depression, with 10 being the greatest). She was experiencing sleep adjustments (reduced sleep period), feelings of guilt and unimportance, low energy, cognitive troubles, psychomotor retardation, and self-destructive ideation. She rejected a strategy or intent associated with this suicidal ideation. Her self-reported cognitive problems materialized as "brain haze" and also amnesia (both short- and long-term), which she attributed to her lifelong clinically depressed mood. The individual was not presently experiencing adjustments in cravings associated with her clinical depression. She had additionally been experiencing anxiousness throughout the previous year, which was new for her. There was no identifiable event or variable that can have contributed to her worsened state of mind law within the past year.

She reported frustration with her social life, profession, and also motivation to complete everyday jobs. She additionally dealt with rest dysregulation due to being a night-shift worker. She consumed a basic American diet plan and lived a sedentary way of living, though she had actually delighted in participating in physical activity in the past. She rejected drug use, but sometimes consumed alcohol. She reported a household history of depression, including her sibling as well as several participants on her mommy's side of the household. Besides 1 month of therapy and the abovementioned previous trial of SSRIs, she had actually not been treated for her clinically depressed mood or anxiousness.

Physical examination of heart, lung, abdominal area, HEENT (head, eyes, ears, nose, throat), and peripheral pulses was unremarkable. She did, nonetheless, present with the blunt affect regular of serious depression.

ANALYSIS ASSESSMENT.

According to the Diagnostic & Statistical Manual of Mental Disorders V (DSM V), major depressive problem (MDD) is diagnosable based upon clinical photo alone if the episode is not attributable to the straight physical results of a substance or other medical condition.17 The person reported that recent blood tests purchased by her primary care doctor were regular. Existing blood work considerations included a total blood matter as well as thyroid-stimulating hormone; nevertheless, we suspected that the chance of problems in these areas being the root cause of her symptoms was reduced.18 Regrettably, we were not able to get the laboratory results to validate. She also denied current use any kind of drugs or substances that might explain her symptoms.

At the first office browse through, she has a PHQ-9 rating of 24 (range: 0 to 27) and a GAD-7 score of 16 (range: 5 to > 15), indicating both serious anxiety as well as anxiousness, respectively. We inferred from her previous therapy with SSRIs and also her personal report of a history of depression that MDD was the working diagnosis. Indeed, based upon the presence of 7 out of 8 major sign criteria for MDD, as well as the chronicity of the problem, the patient was detected with severe, reoccurring MDD without psychotic attributes.

RESTORATIVE TREATMENTS.

Offered the intensity of the person's clinical depression, it was essential to evaluate with the patient the standard-of-care option of SSRIs. Nevertheless, given her previous adverse response and her preference for all-natural therapy, we suggested a well-known state of mind law supplement, 2 grams of fish oil each day, a workout routine, as well as sleep health methods.

The suggested supplement is a mix of nutrients and also botanicals designed to improve mood by providing neurotransmitter and also adrenal support. Ingredients in this supplement include vitamins C, B5, B6, B9, B12, and iodine; amino acids and also natural chemicals L-tyrosine, 5-hydroxytryptophan, as well as gamma-aminobutyric acid (GABA); and also the herbs Eleutherococcus senticosus as well as Rhodiola rosea. Numerous active ingredients in this formula are evidence-based. Vitamin C supports adrenal gland function and lowers oxidative anxiety understood to be present in depression.12 Additionally, B vitamins are essential for energy as well as exec function essential in depression, consisting of natural chemical synthesis (GABA, serotonin, and norepinephrine). A current review summarized substantial proof that supplementation with B vitamins enhances depressive signs and symptoms in both animal as well as human research studies.19 Incorporation of the amino acids as well as neurotransmitters is based upon evidence recommending that tryptophan and also phenylalanine (a forerunner to tyrosine) are eaten by the body in better quantities during inflammatory states. Therefore, it has actually been presumed that depletion of these amino acids contributes to the phenotype of inflammation-based depression.20 A current trial of otherwise-healthy young adults found that eating a diet high in tryptophan boosted state of mind by minimizing depressive signs and symptoms and anxiety1; supplements with tryptophan would rationally have the exact same effect, though there are no current randomized regulated trials confirming this presumption. Moreover, a testimonial published in 1984 discussed mechanistic designs supporting using tyrosine for depression; however, there have been no more professional tests or evaluations on this subject.22 Finally, the natural herbs included in this formula are known to sustain concentration, state of mind, as well as durability to tension, according to both animal studies as well as medical trials.23,24 The suggested dosage of this product was 2 pills twice each day, as advised by the manufacturer.

Fish oil (with a high EPA/DHA ratio) at 2 grams per day was recommended for its extra anti-inflammatory action. Several recent organized reviews as well as meta-analyses compiled professional evidence and also made strong favorable suggestions for supplementation with EPA-rich omega-3-fatty acids for depressive signs.25 We additionally advised that the client take part in moderate-to-high-intensity workout (aerobic or anaerobic) for 3-5 days weekly, which is confirmed to boost depression signs.26,27 Lastly, we made numerous conventional rest hygiene referrals (Figure 1) based upon the client's reported fatigue as well as night-shift job, which per se is related to boosted threat of clinical depression.28 A recent randomized clinical trial of adolescents showed improvement of depression signs and symptoms with rest health suggestions similar to those offered to our patient29; however, there are no medical trials of adults with MDD that specifically investigate the connection between rest hygiene guidance as well as depressive symptoms.

TWO-MONTH FOLLOW-UP.

The person returned to center for a follow-up consultation 8 weeks later (September 2018). She reported considerable signs and symptom alleviation, mentioning, "I more than happy." She reported being certified with the suggestions for the whole period, which she believed contributed to her success. She did not have trouble with following our suggestions besides working out, which she had actually just rebooted within the previous 2 weeks.

The client offered noticeably better as well as more clear in her affect; she made a lot more eye contact, showed no indicators of psychomotor retardation, as well as smiled during the visit. We duplicated the PHQ-9 and also GAD-7 at this browse through, which provided ratings of 2 and also 3, respectively. This reality caused the individual-- that had really felt clinically depressed for much of her life and also had actually completed these kinds often times over the years-- to say loudly, "This is the lowest score I have actually ever before had!" She was delighted with her progression and also prepared to comply with up in 6 weeks to check in.

PRESENT DAY.

Unfortunately, the individual has actually not gone back to the NUNM Facility given that her 2nd follow-up. Therefore, we are unable to report whether she has had the ability to maintain a complete remission, which would certainly require sign improvement for 4-6 months.30.

The student author of this post had the ability to get to the person by phone in November 2018. She reported recent demanding life events, including experiencing a divorce that has actually caused her psychological wellness to be "backwards and forwards" at the time of the call. The client denied self-destructive ideation as well as reported increased durability compared to her previous depressive episodes. However, the trainee was incapable to determine whether the individual was still complying with our previous treatment referrals.

DISCUSSION.

Though the individual was lost to follow-up, this situation is a superb example of effective treatment of clients with extreme MDD that do not tolerate SSRIs or that decrease SSRIs for any kind of other factor. The mix of targeted supplementation with way of living recommendations supported her wellness with several devices.

Nonetheless, this situation is not without restrictions. The writers have to recognize the brief timeline and the fact that the individual was shed to follow-up. While we do think that she has actually maintained some enhancement, based upon her call, we are not able to verify that she has followed her therapy method. We also acknowledge some reliance on the patient's self-report of being updated on screening labs to come to her diagnosis. In spite of these constraints, our company believe that the client's fast response warranted this case report, as well as we take pride in the progression made.

Recalling the Healing Order, we reflect on the idea that this treatment strategy focuses on the bottom fifty percent of our pyramid, highlighting gentle and also effective therapies compared to pharmaceuticals that can have damaging negative effects in the long term (Figure 2).31,32 Particularly, we had the ability to develop her structures of health and wellness with the exercise and also sleep health methods along with promote the body's ability to recover and sustain damaged systems with the supplements. Our company believe this therapy regimen may be a reliable technique for naturopathic doctors to use, and much more study relating to the efficiency of this method in the kind of a relative effectiveness study is required.

The post “CHRONIC SIGNIFICANT DEPRESSION: RAPID ENHANCEMENT UTILIZING NATUROPATHIC TREATMENTS” was seen first on ndnr

Looking for a Naturopath? Drop by Dr. Amauri Wellness Centre here in Toronto.

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riichardwilson · 5 years ago

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Brain Hacks to Boost Motivation and Beat the Work From Home Blues

July 24, 2020 11 min read

Opinions expressed by Entrepreneur contributors are their own.

As the number of days we’re spending in lockdown – or simply still working from home (if we would rather be in the office) – continue to tick by with no clear end in sight, what for some of us was the novelty of working from home has clearly worn off and our days are starting to feel more like “rinse and repeat.” When a routine begins to feel monotonous, we often feel a lack of motivation. And, when our motivation starts to wane, so, too can our productivity.

Physical Intelligence can help. Right now, literally hundreds of chemicals (hormones and neurotransmitters) are racing through each of our bodies in our bloodstream and nervous system. Some of those chemicals have familiar names, such as cortisol, adrenalin and testosterone. Those chemicals largely dictate how we think, feel, speak and behave, yet most of us operate primarily at the mercy of those chemicals – experiencing thoughts, reactions and emotions – without realizing that we can actively manage them. Physical Intelligence is the ability to detect and strategically influence the balance of certain key chemicals so that we can achieve more, stress less and live and work more happily.

Related: 10 Delicious Foods to Feed Both Body and Mind

Physical Intelligence techniques have been used for decades – many drawn from the worlds of sports and the arts – and are all underpinned by neuroscience. There are hundreds of Physical Intelligence techniques – ways of breathing, moving, thinking (e.g., visualizing) and interacting with each other – all easy to incorporate into our day to day life. There are four elements of Physical Intelligence: Strength, Flexibility, Resilience and Endurance, each important for motivation and productivity in different ways.

Strength

When we feel positive about something or someone, we are having a ‘towards’ response in which dopamine (our pleasure and reward chemical) rises and cortisol (our stress chemical) settles to optimal. We feel rewarded, which makes us want to engage more, do more, be more in the situation. When we feel disappointed, demoralized, lacking motivation, angry or unhappy about something, we are having an ‘away’ response, a primary threat response in which cortisol rises and dopamine drops. We feel unrewarded by the situation – therefore, we instinctively move away from it or resist it.

The drop in motivation that many people are experiencing as they face the uninspiring or perhaps worrisome routine of work in lockdown is a classic “away response.” If we can recognize situations, demands and expectations for what they are – triggers of our primary threat (away) or primary reward (towards) responses, then we can be less reactive and more constructive in how we respond. If we’re working with or leading a team (or even raising children) and we know what people need in order to feel fully engaged, we can speak and behave in a way that draws people together, by creating and fostering the chemistry of a ‘towards’ response – whether we’re working together in an office or connecting via videoconference.

Related: How to Strengthen Your Brain for Success

In order to manage our towards and away response and create an environment that actively creates towards responses we need Strength – inner strength, confidence, resolve, the ability to stand our ground and act and think wisely and decisively without threatening others or feeling threatened, being positively assertive, independently minded, astute and highly productive, and able to increase our capacity for achievement. The following strength techniques provide a foundation for preparing yourself to recognize and respond to those towards or away responses and to create towards responses across our teams.

Grounding Yourself: How empowered, confident, and tolerant you feel is greatly impacted by your posture. Grounded posture enables you to feel simultaneously stronger, more present, alert and more at ease. Centering reinforces the chemistry of high testosterone and low cortisol, and supports our dopamine function, enabling us to focus and coordinate our physical and mental energy to achieve and win. To ‘ground’ yourself, feel the weight of your body on the ground or in the chair – rooted rather than ‘uptight’. Continue paced breathing, release tension throughout the body; place your center of mass where you need it (move your body forwards sideways and backward to find the optimal point); breathe down to below the navel (to your center of gravity), and focus. Repeat three times: Balance, Breathe, Focus

Paced Breathing: Become aware of your breathing as you read this. Is it fast or slow, shallow or deep? Many people hold their breath while they are thinking, snatch breaths while writing emails, and breathe too shallowly in business meetings or while cooking supper or watching television. Life interferes with breathing in ways that were not intended, to the detriment of our cognitive function, emotional stability…and our productivity. Paced breathing enables us to power up our brains and stabilizes our emotions. It releases the chemical acetylcholine, which counteracts adrenalin and empowers us to feel mentally/emotionally stable and confident, able to handle situations with clarity, balance, and control.

Ideally, spend 10+ minutes daily breathing diaphragmatically, with a steady count in (through the nose) and out (through the mouth) – in and out counts can be different. Explore counts comfortable for you. A study of South African bankers found that after 21 days of paced breathing, they achieved an average of 62% improvement in cognitive capacity on complex decision-making tasks, whereas poor breathing leads to procrastination and delaying important decisions. Meditation is a great way to bring paced breathing into your daily routine.

Flexibility

Lack of motivation can also be the result of diminished inspiration, especially if we’re following the same old routine – and distracted by uncertainty and worry. To increase inspiration we need to improve our capacity for creativity and innovation, as well as the ability to think divergently (essential for creativity and innovation). These techniques are a good start:

Physical inflexibility leads to mental inflexibility. Loosening tension in your body will help free your mind. Scan your body daily to identify and then address any areas where you are holding tension.

Start walking, even if just around the house. Research indicates that we are 45% more likely to have an innovative idea while walking rather than seated, even if on a treadmill.

Shifting your focus to look at something we find beautiful n art or nature also sparks creativity.

With teams, create cultures based on trust and novelty while encouraging risk-taking. Maintain a positive mood by valuing people’s contributions so that they continue to get deeply immersed in thinking together. Use Open Space and encourage people to make clear plans to implement new ideas agreed upon by the team.

Innovation is particularly important today as organizations work to implement creative solutions in response to the unique challenges and opportunities the pandemic has created.

Related: Entrepreneurs’ Brains Are Wired Differently. Here’s How to Use Yours Right.

Resilience

Resilience is our ability to bounce back from adversity and challenge (such as the current crisis), to remain optimistic in the face of disappointment, to develop a learning mindset…and to build networks of support, particularly effective for increasing productivity.

Neuroeconomist Paul Zak’s research, published in The Trust Factor, reports that in organizations that share information broadly and intentionally build relationships, and where leaders ask for support, there is 76% more engagement, people have 106% more energy, they are 50% more productive, 29% more satisfied with their lives, have 13% fewer days sick and 40% fewer cases of burnout. He has tested oxytocin (our social bonding and trust chemical) levels in the bloodstream of thousands of employees across many industries and cultures and has shown that trust and purpose reinforce each other, creating a mechanism for high oxytocin levels over a longer period. Robust networks and finding support, both boost oxytocin, which helps build trust – and, therefore, are a key part of our happiness and a cornerstone of our resilience.

Building and maintaining those support networks is especially important in the midst of this crisis because we are not able to spend time with each other in person, reducing our oxytocin levels. Make a concerted effort to leverage your personal and professional networks by reaching out to people across your network to offer support. If meeting via videoconference, make eye contact through the camera lens to boost oxytocin in others even from a distance.

Another key component of Resilience is relaxation and recovery. Sometimes lack of motivation and productivity are related to being overworked. If you find that you are working harder or longer hours than usual and with fewer boundaries in the midst of this crisis, make sure that you are allowing enough time for restorative activities. Life is a balancing act of effort and recovery. After pushing ourselves, we must allocate time for recovery. Try the following:

Write REST in blocks in your calendar throughout the week and honor those blocks of time: Retreat (stepping away from all digital devices, media, social media, etc. – giving yourself a mental break), Eat (consuming healthy food, lean protein, vegetables, fruit, limited simple carbohydrates, sugar and alcohol), Sleep (7-9 hours per night inching up the hours, as needed with naps or going to sleep a few minutes earlier each night) and Treat (healthy restorative treats: hikes, a hot bath, soothing cup of tea, playing with children, beautiful music, whatever you find restorative).

Endurance

Endurance refers to mental toughness, perseverance and planning. When working on something that requires extreme patience or a sustained effort over the long term, we need endurance. Visualize an “Endurance Tunnel.” As you move through that tunnel, the walls may start to close in and the light at the end of the tunnel may dim. To keep those walls wide and strong and the light switched on, especially when the going gets tough, these techniques will help increase your motivation, and in turn, your productivity:

Allocate the first two hours of the day to key tasks. Tackling important tasks early elevates testosterone because confronting tasks, (rather than postponing or avoiding them), gives you a sense of moving bravely into new territory. Dopamine is also boosted because you will feel the reward of achievement. Starting the morning with a clear head, when memory is sharp and you are able to quickly absorb information, also enables acetylcholine to balance adrenalin. This confidence and motivation will carry throughout the rest of your day, even if your brain is not quite as sharp as the day progresses. Conversely, procrastination and avoidance lower dopamine levels and increase cortisol levels, perpetuating the cycle of demotivation and lack of productivity.

Self-appreciation and encouragement for and from those around us enable us to endure the difficulties of whatever Endurance Tunnel we are in. It is important to celebrate our own successes and give and receive appreciation in order to fuel dopamine levels that allow us to focus on challenging goals. We need each other, and the support and appreciation we give and receive is an important part of being motivated.

Motivation is improved when we are aligned with our values and core purpose, doing work that puts us in our element, and using our strengths to the fullest. Becoming more conscious of those deep motivations enhances our productivity and makes it more likely that we will persevere.

Language plays a big part in how motivated people feel. We need to use a language of ownership v. blame in order to make critiquing a team or company performance motivational. Consider adopting this team practice… After any important event, meeting or project, one by one, have team members critique themselves first – sharing what went well and where they could improve. Then provide feedback to each other. This practice develops autonomy and relatedness, two critical factors for motivation identified by Edward Deci and Richard Ryan in their 2016 book Self-determination Theory: Basic Psychological Needs in Motivation, Development, and Wellness. Developing a culture where individuals can be autonomous (high dopamine and testosterone) yet strongly bonded (high oxytocin) creates the conditions for ongoing motivation and productivity.

With these Physical Intelligence techniques, you should be able to motivate yourselves and others, enhancing productivity throughout this crisis and beyond.

Claire Dale and Patricia Peyton are the directors of Companies in Motion and authors of award-winning personal development book Physical Intelligence.

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scpie · 5 years ago

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Brain Hacks to Boost Motivation and Beat the Work From Home Blues

July 24, 2020 11 min read

Opinions expressed by Entrepreneur contributors are their own.

Related: 10 Delicious Foods to Feed Both Body and Mind

Strength

Related: How to Strengthen Your Brain for Success

Flexibility

Start walking, even if just around the house. Research indicates that we are 45% more likely to have an innovative idea while walking rather than seated, even if on a treadmill.

Shifting your focus to look at something we find beautiful n art or nature also sparks creativity.

Innovation is particularly important today as organizations work to implement creative solutions in response to the unique challenges and opportunities the pandemic has created.

Related: Entrepreneurs’ Brains Are Wired Differently. Here’s How to Use Yours Right.

Resilience

Endurance

With these Physical Intelligence techniques, you should be able to motivate yourselves and others, enhancing productivity throughout this crisis and beyond.

Claire Dale and Patricia Peyton are the directors of Companies in Motion and authors of award-winning personal development book Physical Intelligence.

Website Design & SEO Delray Beach by DBL07.co

Delray Beach SEO

source http://www.scpie.org/brain-hacks-to-boost-motivation-and-beat-the-work-from-home-blues/

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laurelkrugerr · 5 years ago

Text

Brain Hacks to Boost Motivation and Beat the Work From Home Blues

July 24, 2020 11 min read

Opinions expressed by Entrepreneur contributors are their own.

Related: 10 Delicious Foods to Feed Both Body and Mind

Strength

Related: How to Strengthen Your Brain for Success

Flexibility

Start walking, even if just around the house. Research indicates that we are 45% more likely to have an innovative idea while walking rather than seated, even if on a treadmill.

Shifting your focus to look at something we find beautiful n art or nature also sparks creativity.

Innovation is particularly important today as organizations work to implement creative solutions in response to the unique challenges and opportunities the pandemic has created.

Related: Entrepreneurs’ Brains Are Wired Differently. Here’s How to Use Yours Right.

Resilience

Endurance

With these Physical Intelligence techniques, you should be able to motivate yourselves and others, enhancing productivity throughout this crisis and beyond.

Claire Dale and Patricia Peyton are the directors of Companies in Motion and authors of award-winning personal development book Physical Intelligence.

Website Design & SEO Delray Beach by DBL07.co

Delray Beach SEO

source http://www.scpie.org/brain-hacks-to-boost-motivation-and-beat-the-work-from-home-blues/ source https://scpie1.blogspot.com/2020/07/brain-hacks-to-boost-motivation-and.html

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tipsycad147 · 6 years ago

Text

Astragalus; Adaptogen Herb for Stress and Balance

What are adaptogens?

Adaptogens are herbs that help us adapt to changes and stress caused by physical, biological, emotional, and environmental factors. They can assist in restoring balance within the body and help us defend against both chronic and acute stressors.

One of my favorite adaptogens is astragalus.

Astragalus (Astragalus Membranaceus)

Astragalus is an adaptogenic herb often used in Chinese medicine. It is calming to the Central Nervous System (CNS) and has antimicrobial properties. Astragalus helps support respiratory functions making it useful in times of infection and useful for allergies and asthma. This herb thought to boost the immune system, increase energy, and address fatigue associated with chemotherapy and chronic illness.

Due to it’s antibacterial and antiviral properties, along with its immune-boosting capabilities it may be useful in preventing and decreasing the severity of common colds and respiratory infections. Astragalus may also be used with herbs such as milk thistle to help prevent damage to the liver and kidneys caused by other medications.

Precautions: There are no known contraindications although it may have interactions w/ immunosuppressant drugs.

Culinary Uses:

Incorporating adaptogens into your routine is quick and easy with this Adaptea recipe. Using adaptogens as part of your diet is a great way to get all the amazing stress-busting, and healing benefits of adaptogens without having to take another supplement.

Try this tea and let us know what you think!

Adaptea Recipe

8 grams Astragalus ( 2 slices) 1 tbs Cat Nip 2 tsp Lemon Balm 1 tsp Nettles 1 tsp Red Raspberry Leaves 3 dried Stevia Leaves

Bring astragalus and 4 cups of water to boil and simmer for 20 mins. Turn off heat and add in remaining herbs. Steep covered for 5-10 mins. Strain. Add an additional 4 cups of cool water and allow to cool. Serve over ice.

To serve hot:

Bring astragalus and 8 cups of water to boil and simmer for 20 mins. Turn off heat and add in remaining herbs. Steep covered for 5-10 mins. Strain.

Adaptogens for Holistic Healing

Documentation of the use of adaptogenic herbs exists throughout history. Many were used in traditional Chinese medicine and in Ayurveda for possibly thousands of years. This class of herbs gained attention in the 1940s in Russia as they searched for a substance that would provide strength, stamina and physical superiority. The term adaptogen was coined by Nikolai V. Lazarev, a Soviet scientist, medical doctor, and pharmacologist. According to Lazarev, an adaptogen is an agent that allows an organism to counter adverse physical, chemical, or biological stressors by raising non-specific resistance towards such stress, allowing the organism to adapt to stressful situations.

1. non-toxic

2. produce a non-specific response in the body

3. increase our bodies non-specific adaptogenic response

4. must have a normalising influence on physiology

5. must be able to both stimulate a hypo-functioning system

6. calm/relax or stimulate a hyper-functioning system

In order for an herb to be considered an adaptogen, it must meet all the qualifying criteria but there can be confusion about what actually qualifies a specific herb for the designation. Herbs may be made into tonics which are nutritive and can be taken to help strengthen one system with limited harmful side-effects but are not necessarily an adaptogen. An herb may also be rejuvenating or restorative, but that doesn’t mean it fits into the classification of an adaptogen because they do not meet all the particular criteria that are required to be considered an adaptogen. Adaptogens aren’t tonics for one system of the body. They work to restore overall balance and strengthen the functioning of the body as a whole without impacting the stability of an individual organ or body system. To be an adaptogen, the herb must be able to facilitate changes by a wide range of actions, rather than one specific action, like balancing particular hormones or improving digestion.

Many adaptogens are also anti-inflammatory and reducing overall inflammation will increase energy, boost immunity, and increase cognitive function. All of these are affected when the stress response is induced.

What can adaptogens do for our bodies?

support adrenal function

increase tolerance of stress both physical and emotional

minimise the harmful side effects of toxins

work on a cellular level to protect from oxidative stress

Adaptogens may also help:

produce energy on a cellular level regulate glucose

support metabolic functions

slow ageing

play a role in psychoneuroimmunology by regulating the brain and nervous system

help restore the balance of the endocrine hormones

modulate the immune system

play a role in emotional and physical health

help maintain homeostasis in the body

Many adaptogens help improve focus, support immune system functioning. They provide some other broad-spectrum normalising influence on unbalanced physiological processes. They create change in the body because of their ability to stimulate and balance several systems. They have a normalising effect on the body by toning down a hyper-functioning system and strengthening the action of a hypo-functioning system. The mechanisms of action for these herbs are still not well understood. A great way to think of how adaptogens impact our bodies is that they are the positive mirror to the harmful effects of stress.

Now all this sounds wonderful, like a magic solution even, but our bodies are not meant to live under continued exposures to stress so while this class of herbs can help you reduce the effects of chronic or acute stress, in order to truly break out of the cycle, it is necessary to find the root causes of your stress and address them. Adaptogens are not meant to be taken years on end; they are made to assist our bodies as we work on implementing healthier lifestyle habits, or in times of situational stress. Many times, when we find ourselves taking a bunch of supplements and nothing is working; it’s because there is something more profound at play, and more often than not its a combination of the before mentioned factors.

In addition to the changes caused by physical, biological, emotional, and environmental factors as well as their ability to reduce inflammation which will increase energy, boost immunity and increase cognitive function, adaptogens may also help to improve blood sugar imbalances, anxiety, depression, arthritis, and adrenal fatigue to name a few.

Cold and Flu Natural Prevention & Protocols

The cold and flu are viral infections that infect the respiratory tract.

Viruses are the smallest microbe which infects human. The discovery of viruses are relatively new in medical history; it wasn’t until the 1930-40’s that there were microscopes powerful enough to see viruses. Since then have been over 30k different viruses identified.

Viruses are not living, and it’s really important to stress here, antibiotics are completely ineffective in addressing viral infections. In fact, they will actually make a viral infection worse by killing off the beneficial bacteria you need to help fight the infection.

Antibiotics negatively impact our gut health on an average of 18 months after each use and also increases your chances of recurrent infections

Certain botanicals can actually inhibit viruses from replicating by deprogramming the viruses so that once they penetrate a cell they can’t overtake and reprogram it, halting the progression of a disease. Other herbs can attack the spikes on the outside of a virus so it can’t attach to the cell, others may prevent a virus from the penetrating a cell. Our botanicals can work on multi-levels to help us prevent or shorten the duration of these illnesses.

For illnesses like the cold and flu self-awareness is really important.

This is the where we may have had an exposure of some kind of indication that we may be coming down with something It’s the early warning signs where we need to amp up our prevention methods.

One botanical we can use for a multi-level prevention and treatment option is elderberry.

Elderberry Elderberry works by actually inhibiting viral replication, so it is best taken at the first sign of symptoms to stop the progression of the disease.

This is treating at the root cause. We are not addressing symptoms with elderberry. You may add other botanical to your protocol to address symptoms but we are really looking at inhibiting viral reproduction here. In a 2016 study evaluating cold symptoms among travellers, elderberry supplementation was compared to placebo. The elderberry treatment group experienced less total sick days, they also experienced less severe symptoms on a rating scale. Here they are taking elderberry as a preventative when their exposure is higher.

Where people often run into issues when using natural remedies, is dosing, frequency and consistency. As an herbalist and aromatherapist, it is one of the biggest mistakes I see when people find their natural remedies not working.

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wendyjimenezus · 6 years ago

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Studies Claim Complete Social Isolation Causes Physical and Mental Conditions

The idea of complete social isolation has become a thing of the past with the world being at people fingertips, but the effects it can have on one’s mind, and bodies have been proven through countless studies to be harmful and detrimental. However, the question remains, why is isolations such a difficult concept for humans to face.

Studies indicate that one of the reasons living in total isolation is difficult is because as humans we are generally social creatures. For example, people that have lived in isolation environments including Antarctica report that loneliness seems to be the most challenging part of the job. An Israeli adventurer and author, Yossi Ghinsberg survived months alone in the Amazon forest and confirmed that loneliness was what he suffered from the most and even admitted to creating imaginary friends to keep himself stimulated.

The reason loneliness can be damaging to both peoples mental and physical health is socially isolated people are less equipped to deal with stressful situations. People have higher chances of feeling depress and may have difficulties processing or understanding necessary information. Data show the results of this can lead to problems in making decisions and memory storage along with recalling minor situations.

Experts also suggest that people who are lonely are also more likely to contract an illness, they also found that a person’s immune system responds differently to fighting common viruses, making them sensitive to diseases.

However, the impacts differ when people are placed in physically isolating environments. This usually happens when people are in solitary confinement it can have adverse psychological effects on prisoners, which were increases in anxiety and panic attacks, increased levels of paranoia and also being less able to think with a clear mind. Prison health reports show prisoners report long-term mental health problems after they spent significant time behind bars.

A case involving an Australian woman named Natascha Kampusch was abducted at the age of 10 and held captive in a cellar for eight years, explained in her biography that the lack of light and human interaction mentally destroyed her. She reported that the endless hours and days spent alone made her listen to her captor’s orders and manipulations.

Total darkness has a considerable role in the impacts of isolation, causing both psychological and physical consequences. The main result of being in complete darkness is that it will disrupt an individual’s sleep cycle. Experts explain that two of the fundamental mechanisms for sleep cycle regulation, the hormone melatonin, and the brains suprachiasmatic nucleus, both rely on light to function.

The difference between daylight and night time are the way it reduces levels of melatonin, helping people feel awake. It also helps the suprachiasmatic nucleus to reset the waking time if the persons sleep cycle starts to get disrupted. These disruptions to the circadian rhythm can make us feel depressed and fatigued. Studies have also linked cancer, insulin resistance, and heart disease, along with physical problems such as obesity and premature aging.

Hallucinations have been reported among people placed in isolation, due to the lack of stimuli that causes people to misattribute internal thoughts and feelings as occurring in the outer environment. Just put- the brain needs stimulation to work at its full potential.

Despite the impacts being severe, they are almost all reversible. Once the individual is once again exposed to daylight there sleep cycle will correct its self, although this can take weeks or even months. Reconnecting with human beings can decrease the effects of mental and physical health due to being lonely. Some cases people were held captive and in total isolation against there will develop long-term mental health issues, such as PTSD or Severe Depression.

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The Recover is an unbiased substance abuse and mental health news provider. Helping individuals looking for the right treatment programs in their area. Also providing information on drug rehab centers for addiction recovery.

Author: Kennedy Adams

Organization: TheRecover.com

Address: 402 West Broadway, #400, San Diego, CA 92101

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wandagreeneus · 6 years ago

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Studies Claim Complete Social Isolation Causes Physical and Mental Conditions

Author: Kennedy Adams

Organization: TheRecover.com

Address: 402 West Broadway, #400, San Diego, CA 92101

from http://www.ivdaily.com/studies-claim-complete-social-isolation-causes-physical-and-mental-conditions

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donaldehillfl · 6 years ago

Text

Studies Claim Complete Social Isolation Causes Physical and Mental Conditions

Author: Kennedy Adams

Organization: TheRecover.com

Address: 402 West Broadway, #400, San Diego, CA 92101

source http://www.ivdaily.com/studies-claim-complete-social-isolation-causes-physical-and-mental-conditions from Ivdaily https://ivdaily.blogspot.com/2019/01/studies-claim-complete-social-isolation.html

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paullassiterca · 7 years ago

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Top 10 Health Searches for 2018

Below each search term heading, the most popular article of the year is hyperlinked; just click on it to read the full article.

No. 1 — High Blood Pressure

No. 2 — Ketogenic Diet

No. 3 — Beets

No. 4 — Vitamin D

No. 5 — Intermittent Fasting

No. 6 — Flu Shot Facts

No. 7 — Sucralose (Splenda)

I also review how to determine whether you might be having a reaction to artificial sweeteners, and how to file an adverse reaction report with the U.S. Food and Drug Administration.

No. 8 — Probiotics

No. 9 — Berberine

A number of new supplements have gained recognition in the past year, with berberine, a powerful AMPK activator, being among the most popular and most-searched-for.

No. 10 — Cancer

Two of the most popular cancer-related articles for the year were “How Curcumin Targets Cancer” and “Chemotherapy Is Losing Its Luster,” which address prevention and treatment respectively.

The remarkable benefits of nutritional ketosis and fasting as adjuncts to conventional cancer treatment are also detailed in “Metabolically Supported Therapies for the Improvement of Cancer Treatment,” which features an interview with Dr. Abdul Slocum and Travis Christofferson, author of "Tripping Over the Truth: How the Metabolic Theory of Cancer is Overturning One of Medicine's Most Entrenched Paradigms.”

from HealthyLife via Jake Glover on Inoreader http://articles.mercola.com/sites/articles/archive/2018/12/24/top-google-health-search-2018.aspx

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cazahealthcenter · 7 years ago

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Curcumin: Benefits and Side effects of the active Turmeric component

https://cazahealthcenter.com/curcumin-benefits-side-effects/

Curcumin: Benefits and Side effects of the active Turmeric component

Indian turmeric is indicated as the best spice in the world market because of its high curcumin active component. Curcuminoids, phenolic yellowish pigments, are the major bioactive constituents of the Curcuma species including Curcuma longa (Turmeric). The yellow root (Indian saffron) has been in use from ancient time as a spice, food preservative, coloring agent, cosmetic and in the traditional medicine.

Why is Turmeric “Spice of Life” so healthy?

The golden plant grows up to a meter high and is known as the “spice of life.” The special feature of the plant, however, is not the colorful flower, but the so-called rhizomes. These are the bulbous of the plant, which we can buy as curcuma root.

But turmeric is not only used as a spice and colorant – the hype comes about through the health-promoting effect of the super root. For some years now, it has had the image of a “panacea” – in Ayurveda and natural medicine, the healthy effects of curcumin have been known for millennia.

Because of its natural polyphenolic structure curcumin is being ivestigated from many Researchers in term of its biological activities such as:

anti-inflammatory, anti-cancer, anti-protozoal, anti-viral, anti-bacterial and has been found to be effective for treatment of Alzheimer, depression, headaches, fibromyalgia, leprosy, fever, menstrual problems, water retention, worms, and kidney problems etc.

The current trends in curcumin research is concentrated on the development of effective delivery systems that will increase its stability, hydrophilicity, bioavailability as well as targeted delivery with enhanced therapeutic effects.

As a first aid measure at the beginning of each inflammation, we recommend one teaspoon of turmeric with a little warm water for two days. For sore throat, gargling with turmeric water is recommended.

Curcumin Medical Uses and its proven Helath benefits

Turmeric has been used as a yellow dye, flavoring agent, and a traditional remedy in Asian folk medicines for the last 2000 years.

In fact, Herbal experts consider Turmeric as a safe natural yellow pigments used for food coloring and traditional drugs with a variety of biological functions such as antitumor, anti-inflammatory and antioxidant activities.

They are recognized as being responsible for most of their therapeutic effects and have been shown to exhibit a wide range of biological activities.

No significant adverse effects were found in volunteers who received a single oral administration of CUR with doses up to 12g/d in clinical studies, and it has been demonstrated that curcuminoids are safe compounds.

Due to their excellent activities and low toxicity, curcuminoids have been the center point of much research over the past three decades. Studies have reveald that curcuminoids are nontoxic to humans even at a dose of 8000 mg/d taken continuously (Cheng, 2001).

The medicinal uses of turmeric and curcumin are indeed diverse, ranging from cosmetic face cream to the prevention of Alzheimer’s disease. Turmeric is also qualified as the queen of natural Cox-2 inhibitors (Duke, 2003).

Recently, many Researchers are focusing on its antioxidant, hepatoprotective, anti-inflammatory, anticarcinogenic, and antimicrobial properties, in addition to its use in cardiovascular and gastrointestinal disorders.

Curcumin treats Inflammation

To demonstrating safety on its use, Curcumin showed anti-inflammatory activity. It is able to inhibit the lipopolysaccharide (LPS)-induced production of TNF-α, IL-1β, and the activation of NF-κ-B in human monocytic derived cells.

The in vitro results suggested that the nanoemulsion is a potential drug delivery system for inflammatory pain management. The anti-inflammatory mechanism of curcumin involves the Nrf2-keap1 pathway and alleviation of oxidative stress.

In this context, Zhang et al. (1999) and Goel, Boland, and Chauhan (2001) showed that curcumin is able to inhibit the cyclooxygenase-2 enzyme expression resulting in prostaglandin synthesis suppression. Therefore, athletes feel better and less broken after intensive training, when they regularly take Turmeric as a spice.

Additionally, others studies demonstrated that curcumin-loaded elastic vesicles is more effective than free curcumin in a model of acute topic inflammation and cotton pellet-induced chronic inflammation.

This improved therapeutic efficacy, according to the authors, is due to the improvement in flux across murine skin.

Turmeric for stroke and heart attack

The antioxidant turmeric also prevents the oxidation of cholesterol. And cholesterol only becomes really dangerous when it is oxidized, because high levels of homocysteine can damage the walls of the vessel and are considered to be important risk factors for atherosclerotic deposits and heart disease.

Turmeric also contains vitamin B6. Together with vitamin B12 and folic acid , this vitamin ensures that the homocysteine level does not rise too high. It could prevent platelet build-up along the walls of an injured blood vessel.

Platelets collecting at the site of a damaged blood vessel cause blood clots to form and blockage of the artery as well. The efficacy of turmeric in lowering blood plasma lipid was evaluated in rabbits.

The antioxidant property of an ethanolic extract of the rhizomes of C. longa on the lipid peroxidation of liver mitochondria and microsome membranes in atherosclerotic rabbits was evaluated.

It was concluded that the active compounds present in this extract might protect the prevention of lipoperoxidation of subcellular membranes in a dosage-dependent manner, and thus help with the prevention of atherosclerosis

Turmeric inhibits cancer cell lines

Turmeric on the one hand should be able to prevent the formation of tumors, thus acting cancer prevention. On the other hand, a new study indicates that turmeric can prevent metastasis even in cancer that is already present, namely in breast cancer , so that the cancer cell does not spread to the lungs.

Turmeric acts as a switch special transcription factors. These regulate all genes needed for tumorigenesis. Turmeric simply shuts off those transcription factors and stops the growth and spread of cancer cells.

Curcumin is yet another anti-cancer or cell-protecting mechanism. According to US-scientists, it strengthens the membranes of the body’s cells, thereby increasing their resistance to pathogens.The curcumin molecules are incorporated into the lipid bilayer of the cell membranes and thus stabilize them.

However, only the healthy cells are strengthened and stabilized. Interestingly, the membrane of cancer cells became more permeable and lost stability in the corresponding studies by the incorporation of the curcumin.

Curcumin helps diabetics regulate blood sugar levels

Diabetes is one of the major risk factors for cataractogenesis. Initial studies have shown that curcumin has a very positive effect on elevated blood sugar levels.

Aldose reductase has been reported to play an important role in sugar-induced cataract. The aldose reductase inhibitory activity of O.sanctum, W. somnifera, C. longa, and A. indica was studied together with their effect on sugarinduced cataractogenic changes in rat lenses in vitro (Halder et al., 2003).

As a potent antioxidant, curcumin is useful in preventing glucose-induced oxidative stress in the endothelial cells and in the heart of diabetic animals. Because the longa component apparently improves the insulin sensitivity of the cells, so that more blood sugar can be absorbed into the cells.

It is therefore believed that regular consumption of turmeric or the use of curcumin in diabetes could facilitate the control of blood sugar levels .

It has also been observed that short-term treatment of diabetic rats with curcumin prevents diabetes-induced decreased antioxidant enzyme levels and kidney dysfunction; an important activity by the fact that diabetic nephropathy is a major cause of morbidity in diabetic patients.

Use, Dosage and Side Effects of Turmeric

Turmeric is available as a ground spice almost everywhere. To be sure that the turmeric has not been irradiated, you should only use turmeric in organic quality .

In order to benefit from the positive qualities of the superfood, the consumption of half a teaspoon of turmeric powder is sufficient throughout the day – as seasoning in food, in warm milk or as a “shot” with water or juice, lemon and some oil.

Turmeric is particularly good in rice, potato and vegetable dishes. The bioavailability and thus the effect of curcumin can be significantly increased when taken together with with some oil and piperine, a black pepper active ingredient.

Curcumin – combined with piperine – is also is already available in capsules, which not only makes it easier to take, but also helps to absorb sufficient amounts of curcumin every day.

What are the side effects of turmeric?

Even in very high doses, there are no side effects after turmeric intake. In the 4,000 studies published so far no side effects have occurred at normal doses. Turmeric can be well integrated into the daily diet.

So again, that the good effects are really guaranteed, you should buy organic quality.

Side effects of excessive intake of turmeric are also few, but most of the problems described relate to the gastrointestinal tract: upset stomach, diarrhea or flatulence. If you find such side effects in you, first reduce the dosage of turmeric.

For a treatment of existing diseases, the concentration of turmeric in powder and root is not enough, so capsules are better. Various manufacturers combine curcumin with piperine for better bioavailability of antioxidant curcumin.

Since there is still no scientific evidence on the efficacy of turmeric for pregnant women, turmeric should be treated with caution by pregnant women.

Why should not turmeric be eaten raw?

Turmeric can be used just like ginger fresh and raw, for example, cut into small pieces or finely grated. Fresh turmeric, however, tastes more bitter than the powder – and therefore it is not for everyone a taste experience and not very common.

Why should I heat turmeric?

In addition to oil and piperine, heat also helps to provide the body with better curcumin. In addition to the better development of the flavorings, the active ingredients of turmeric can be better absorbed by heating.

Natural bleaching: Why does turmeric make teeth whitish?

Radiantly beautiful teeth thanks to turmeric, the yellow spice? Actually, that sounds a bit absurd. But: It really works! For a natural bleaching for the teeth you need: 1 teaspoon coconut oil mixed with ½ tsp turmeric. Mix the two ingredients together and then brush your teeth with them (due to the risk of discolouration, it is better to use an old toothbrush).

Then you let the mass act for 5 minutes and then rinse your mouth with plenty of water – voià, your hollywood rays are done. With regular use, turmeric not only has a positive effect on your tooth color, but also solves plaque.

With its antibacterial, anti-inflammatory and analgesic properties, turmeric can help prevent swelling and inflammation in the mouth.

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caremobile · 8 years ago

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Toxic Substances and Hazardous and Nuclear Wastes control Act of 1990

Republic of the Philippines Congress of the Philippines Metro Manila

Eighth Congress

Republic Act No. 6969 October 26, 1990

AN ACT TO CONTROL TOXIC SUBSTANCES AND HAZARDOUS AND NUCLEAR WASTES, PROVIDING PENALTIES FOR VIOLATIONS THEREOF, AND FOR OTHER PURPOSES

Be it enacted by the Senate and House of Representatives of the Philippines in Congress assembled::

Section 1. Short title. – This Act shall be known as the "Toxic Substances and Hazardous and Nuclear Wastes Control Act of 1990."

Section 2. Declaration of Policy. – It is the policy of the State to regulate, restrict or prohibit the importation, manufacture, processing, sale, distribution, use and disposal of chemical substances and mixtures that present unreasonable risk and/or injury to health or the environment; to prohibit the entry, even in transit, of hazardous and nuclear wastes and their disposal into the Philippine territorial limits for whatever purpose; and to provide advancement and facilitate research and studies on toxic chemicals.

Section 3. Scope. – This Act shall cover the importation, manufacture, processing, handling, storage, transportation, sale, distribution, use and disposal of all unregulated chemical substances and mixtures in the Philippines, including the entry, even in transit as well as the keeping or storage and disposal of hazardous and nuclear wastes into the country for whatever purpose.

Section 4. Objectives. – The objectives of this Act are:

a) To keep an inventory of chemicals that are presently being imported, manufactured, or used, indicating, among others, their existing and possible uses, test data, names of firms manufacturing or using them, and such other information as may be considered relevant to the protection of health and the environment;

b) To monitor and regulate the importation, manufacture, processing, handling, storage, transportation, sale, distribution, use and disposal of chemical substances and mixtures that present unreasonable risk or injury to health or to the environment in accordance with national policies and international commitments;

c) To inform and educate the populace regarding the hazards and risks attendant to the manufacture, handling, storage, transportation, processing, distribution, use and disposal of toxic chemicals and other substances and mixture; and

d) To prevent the entry, even in transit, as well as the keeping or storage and disposal of hazardous and nuclear wastes into the country for whatever purpose.

Section 5. Definition. – As used in this Act:

a) Chemical substance means any organic or inorganic substance of a particular molecular identity, including:

i) Any combination of such substances occurring in whole or in part as a result of chemical reaction or occurring in nature; and

ii) Any element or uncombined chemical.

b) Chemical mixture means any combination of two or more chemical substances if the combination does not occur in nature and is not, in whole or in part, the result of a chemical reaction, if none of the chemical substances comprising the combination is a new chemical substance and if the combination could have been manufactured for commercial purposes without a chemical reaction at the time the chemical substances comprising the combination were combined. This shall include nonbiodegradable mixtures.

c) Process means the preparation of a chemical substance or mixture after its manufacture for commercial distribution:

i) In the same form or physical state or in a different form or physical state from that which it was received by the person so preparing such substance or mixture; or

ii) As part of an article containing a chemical substance or mixture.

d) Importation means the entry of a products or substances into the Philippines (through the seaports or airports of entry) after having been properly cleared through or still remaining under customs control, the product or substance of which is intended for direct consumption, merchandising, warehousing, or for further processing.

e) Manufacture means the mechanical or chemical transformation of substances into new products whether work is performed by power-driven machines or by hand, whether it is done in a factory or in the worker's home, and whether the products are sold at wholesale or retail.

f) Unreasonable risk means expected frequency of undesirable effects or adverse responses arising from a given exposure to a substance.

g) Hazardous substances are substances which present either:

1) short-term acute hazards, such as acute toxicity by ingestion, inhalation or skin absorption, corrosivity or other skin or eye contact hazards or the risk of fire or explosion; or

2) long-term environmental hazards, including chronic toxicity upon repeated exposure, carcinogenicity (which may in some cases result from acute exposure but with a long latent period), resistance to detoxification process such as biodegradation, the potential to pollute underground or surface waters, or aesthetically objectionable properties such as offensive odors.

h) Hazardous wastes are hereby defined as substances that are without any safe commercial, industrial, agricultural or economic usage and are shipped, transported or brought from the country of origin for dumping or disposal into or in transit through any part of the territory of the Philippines.

Hazardous wastes shall also refer to by-products, side-products, process residues, spent reaction media, contaminated plant or equipment or other substances from manufacturing operations, and as consumer discards of manufacture products.

i) Nuclear wastes are hazardous wastes made radioactive by exposure to the radiation incidental to the production or utilization of nuclear fuels but does not include nuclear fuel, or radioisotopes which have reached the final stage of fabrication so as to be usable for any scientific, medical, agricultural, commercial, or industrial purpose.

Section 6. Function, Powers and Responsibilities of the Department of Environment and Natural Resources.– The Department of Environment and Natural Resources shall be the implementing agency tasked with the following functions, powers, and responsibilities:

a) To keep an updated inventory of chemicals that are presently being manufactured or used, indicating, among others, their existing and possible uses, quality, test data, names of firms manufacturing or using them, and such other information as the Secretary may consider relevant to the protection of health and the environment;

b) To require chemical substances and mixtures that present unreasonable risk or injury to health or to the environment to be tested before they are manufactured or imported for the first time;

c) To require chemical substances and mixtures which are presently being manufactured or processed to be tested if there is a reason to believe that they pose unreasonable risk or injury to health or the environment;

d) To evaluate the characteristics of chemicals that have been tested to determine their toxicity and the extent of their effects on health and the environment;

e) To enter into contracts and make grants for research, development, and monitoring of chemical substances and mixtures;

f) To conduct inspection of any establishment in which chemicals are manufactured, processed, stored or held before or after their commercial distribution and to make recommendations to the proper authorities concerned;

g) To confiscate or impound chemicals found not falling within said acts cannot be enjoined except after the chemicals have been impounded;

h) To monitor and prevent the entry, even in transit, of hazardous and nuclear wastes and their disposal into the country;

i) To subpoena witnesses and documents and to require other information if necessary to carry out the provisions of this Act;

j) To call on any department, bureau, office, agency, state university or college, and other instrumentalities of the Government for assistance in the form of personnel, facilities, and other resources as the need arises in the discharge of its functions;

k) To disseminate information and conduct educational awareness campaigns on the effects of chemical substances, mixtures and wastes on health and environment; and

l) To exercise such powers and perform such other functions as may be necessary to carry out its duties and responsibilities under this Act.

Section 7. Inter-Agency Technical Advisory Council. – There is hereby created an Inter-Agency Technical Advisory Council attached to the Department of Environment and Natural Resources which shall be composed of the following officials or their duly authorized representatives:

Secretary of Environment and Natural Resources

Chairman

Secretary of Health

Member

Director of the Philippine Nuclear Research Institute

Member

Secretary of Trade and Industry

Member

Secretary of Science and Technology

Member

Secretary of National Defense

Member

Secretary of Foreign Affairs

Member

Secretary of Labor and Employment

Member

Secretary of Finance

Member

Secretary of Agriculture

Member

Representative from a non-governmental organization on health and safety

Member

The representative from the non-governmental organization shall be appointed by the President for a term of three (3) years.

The Council shall have the following functions:

a) To assist the Department of Environment and Natural Resources in the formulation of the pertinent rules and regulations for the effective implementation of this Act;

b) To assist the Department of Environment and Natural Resources in the preparation and updating of the inventory of chemical substances and mixtures that fall within the coverage of this Act;

c) To conduct preliminary evaluation of the characteristics of chemical substances and mixtures to determine their toxicity and effects on health and the environment and make the necessary recommendations to the Department of Environment and Natural Resources; and

d) To perform such other functions as the Secretary of Environment and Natural Resources may, from time to time, require.

Section 8. Pre-Manufacture and Pre-Importation Requirements. – Before any new chemical substance or mixture can be manufactured, processed or imported for the first time as determined by the Department of Environment and Natural Resources, the manufacturer, processor or importer shall submit the following information: the name of the chemical substance or mixture; its chemical identity and molecular structure; proposed categories of use; an estimate of the amount to be manufactured, processed or imported; processing and disposal thereof; and any test data related to health and environmental effects which the manufacturer, processor or importer has.

Section 9. Chemicals Subject to Testing. – Testing shall be required in all cases where:

a) There is a reason to believe that the chemical substances or mixture may present an unreasonable risk to health or the environment or there may be substantial human or environmental exposure thereto;

b) There are insufficient data and experience for determining or predicting the health and environmental effects of the chemical substance or mixture; and

c) The testing of the chemical substance or mixture is necessary to develop such data.

The manufacturers, processors or importers shall shoulder the costs of testing the chemical substance or mixture that will be manufactured, processed, or imported.

Section 10. Action by the Secretary of Environment and Natural Resources of his Duly Authorized Representative. – The Secretary of Environment and Natural Resources or his duly authorized representative shall, within ninety (90) days from the date of filing of the notice of manufacture, processing or importation of a chemical substance or mixture, decide whether or not to regulate or prohibit its importation, manufacture, processing, sale, distribution, use or disposal. The Secretary may, for justifiable reasons, extend the ninety-day pre-manufacture period within a reasonable time.

Section 11. Chemical Substances Exempt from Pre-Manufacture Notification. – The manufacture of the following chemical substances or mixtures shall be exempt from pre-manufacture notification:

a) Those included in the categories of chemical substances and mixtures already listed in the inventory of existing chemicals;

b) Those to be produced in small quantities solely for experimental or research and developmental purposes;

c) Chemical substances and mixtures that will not present an unreasonable risk to health and the environment; and

d) Chemical substances and mixtures that exist temporarily and which have no human or environmental exposure such as those which exist as a result of chemical reaction in the manufacture or processing of a mixture of another chemical substance.

Section 12. Public Access to Records, Reports or Notification. – The public shall have access to records, reports, or information concerning chemical substances and mixtures including safety data submitted, data on emission or discharge into the environment, and such documents shall be available for inspection or reproduction during normal business hours except that the Department of Environment and Natural resources may consider a record, report or information or particular portions thereof confidential and may not be made public when such would divulge trade secrets, production or sales figures or methods, production or processes unique to such manufacturer, processor or distributor, or would otherwise tend to affect adversely the competitive position of such manufacturer, processor or distributor. The Department of Environment and Natural Resources, however, may release information subject to claim of confidentiality to a medical research or scientific institution where the information is needed for the purpose of medical diagnosis or treatment of a person exposed to the chemical substance or mixture.

Section 13. Prohibited Acts. – The following acts and omissions shall be considered unlawful:

a) Knowingly use a chemical substance or mixture which is imported, manufactured, processed or distributed in violation of this Act or implementing rules and regulations or orders;

b) Failure or refusal to submit reports, notices or other information, access to records, as required by this Act, or permit inspection of establishment where chemicals are manufactured, processed, stored or otherwise held;

c) Failure or refusal to comply with the pre-manufacture and pre-importation requirements; and

d) Cause, aid or facilitate, directly or indirectly, in the storage, importation, or bringing into Philippines territory, including its maritime economic zones, even in transit, either by means of land, air or sea transportation or otherwise keeping in storage any amount of hazardous and nuclear wastes in any part of the Philippines.

Section 14. Criminal Offenses and Penalties. –

a) (i) The penalty of imprisonment of six (6) months and one day to six (6) years and one day and a fine ranging from Six hundred pesos (P600.00) to Four thousand pesos (P4,000.00) shall be imposed upon any person who shall violate section 13 (a) to (c) of this Act and shall not be covered by the Probation Law.f the offender is a foreigner, he or she shall be deported and barred from any subsequent entry into the Philippines after serving his or her sentence;

ii) In case any violation of this Act is committed by a partnership, corporation, association or any juridical person, the partner, president, director or manager who shall consent to or shall knowingly tolerate such violation shall be directly liable and responsible for the act of the employee and shall be criminally liable as a co-principal;

(iii) In case the offender is a government official or employee, he or she shall, in addition to the above penalties, be deemed automatically dismissed from office and permanently disqualified from holding any elective or appointive position.

b) (i) The penalty of imprisonment of twelve (12) years and one day to twenty (20) years, shall be imposed upon any person who shall violate section 13 (d) of this Act.f the offender is a foreigner, he or she shall be deported and barred from any subsequent entry into the Philippines after serving his or her sentence;

(ii) In the case of corporations or other associations, the above penalty shall be imposed upon the managing partner, president or chief executive in addition to an exemplary damage of at least Five hundred thousand pesos (P500,000.00).f it is a foreign firm, the director and all officers of such foreign firm shall be barred from entry into the Philippines, in addition to the cancellation of its license to do business in the Philippines;

(iii) In case the offender is a government official or employee, he or she in addition to the above penalties be deemed automatically dismissed from office and permanently disqualified from holding any elective or appointive position.

c) Every penalty imposed for the unlawful importation, entry, transport, manufacture, processing, sale or distribution of chemical substances or mixtures into or within the Philippines shall carry with it the confiscation and forfeiture in favor of the Government of the proceeds of the unlawful act and instruments, tools or other improvements including vehicles, sea vessels, and aircrafts used in or with which the offense was committed. Chemical substances so confiscated and forfeited by the Government at its option shall be turned over to the Department of Environment and Natural resources for safekeeping and proper disposal.

d) The person or firm responsible or connected with the bringing or importation into the country of hazardous or nuclear wastes shall be under obligation to transport or send back said prohibited wastes;

Any and all means of transportation, including all facilities and appurtenances that may have been used in transporting to or in the storage in the Philippines of any significant amount of hazardous or nuclear wastes shall at the option of the government be forfeited in its favor.

Section 15. Administrative Fines. – In all cases of violations of this Act, including violations of implementing rules and regulations which have been duly promulgated and published in accordance with Section 16 of this Act, the Secretary of Environment and Natural Resources is hereby authorized to impose a fine of not less than Ten thousand pesos (P10,000.00), but not more than Fifty thousand pesos (P50,000.00) upon any person or entity found guilty thereof. The administrative fines imposed and collected by the Department of Environment and Natural Resources shall accrue to a special fund to be administered by the Department exclusively for projects and research activities relative to toxic substances and mixtures.

Section 16. Promulgation of Rules and Regulations. – The Department of Environment and Natural Resources, in coordination with the member agencies of the Inter-Agency Technical Advisory Council, shall prepare and publish the rules and regulations implementing this Act within six months from the date of its effectivity.

Section 17. Appropriations. – Such amount as may be necessary to implement the provisions of this Act is hereby annually appropriated and included in the budget of the Department of Environment and Natural Resources.

Section 18. Separability Clause. – If any provision of this Act is declared void or unconstitutional, the remaining provisions thereof not affected thereby shall remain in full force and effect.

Section 19. Repealing Clause. – All laws, presidential decrees, executive orders and issuances, and rules and regulations which are inconsistent with this Act are hereby repealed or modified accordingly.

Section 20. Effectivity. – This Act shall take effect after fifteen (15) days following its publication in the Official Gazette or in any newspaper of general circulation.

Approved: October 26, 1990

The Lawphil Project - Arellano Law Foundation

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artecolonialvenezolano-blog1 · 8 years ago

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Maintenance tips to help your air conditioning

The majority of houses are warmed as well as cooled down with a main, whole-home, Home heating, Aerating, as well as Air-Conditioning system (HVAC). The HVAC could well be just one of one of the most pricey and also power starving systems in the residence, so the a lot more you learn about your HVAC, the much better. A knowledgeable home owner will certainly conserve cash and also have a much healthier, a lot more comfy residence.

HVAC System Parts

Central HVAC systems are typically called "split" systems since several of the elements are set up inside the house and also a few of the parts are set up outside a residence. Inside your house, typically mounted in the cellar, attic room, or a wardrobe, you'll discover the heating system (oil, gas, or electrical) and also the evaporator part of the air-conditioner. You'll additionally locate the blower (often called an air trainer), which offers both the heating system and also the air-conditioner. Connected to the blower are air ducts, which are tubes working as paths to supply warmed or cooled down air to different areas in your home.

If your HVAC system is a heatpump, it will not have a different heating system. Dave Moody, an HVAC sector pro with Solution Professionals, describes, "A heatpump functions like a normal air-conditioner in the summertime, after that basically operates in opposite in the wintertime, offering both cooling down and also warming functions." A heat-pump system will certainly still have interior and also exterior parts.

Outside your house you'll discover the compressor and also condenser elements of the main air-conditioner (or heatpump), which are installed in a steel closet with a huge follower.

One option to a split-system is called a "packaged" system, where all parts are mounted in a solitary system outside the residence, with air ducts getting in with the wall surface of the house. These devices could be more effective for a home owner that does not intend to squander area on the inside of their residence with heating and cooling tools.

Seldom resolved in the majority of HVAC setups is the "V"-- air flow. The majority of residences count on seepage, or air that leaks in via spaces and also fractures in the house's covering, for minimal fresh air. Solution Specialists' Moody claims, "As interior air high quality (IAQ) is significantly linked as a large consider human health issue, mechanical air flow systems are coming to be much more typical." Much more concerning that in the "air flow" area listed below.

Home heating

Oil or gas heating systems function by shedding oil or gas in a secured chamber. The blower flows air around the beyond the chamber, where the air soaks up warm prior to it is distributed back right into the house with the air ducts. The by-products of melting oil and also gas are burning gases, a few of which are deadly. Those gases are ducted to the outdoors by means of a steel or plastic flue. More recent systems consist of a 2nd pipeline which collects air from outside the residence for the fire in the burning chamber. Older systems drew conditioned air from inside the residence for this objective. As that air was made use of in burning, chilly air from outside the residence was pulled through fractures in the structure's covering, making the house really feel breezy and also chilly, and also reducing performance. "Newer heating systems, by generating outdoors air for burning, do not draw substitute air via a residence's spaces as well as splits," claims Moody, "That indicates they're a lot more effective, run even more securely, as well as make a house a lot more comfy compared to older heaters."

Electric heating systems utilize electrical strip components which transform electrical power to warmth, similar to in a toaster oven or hair-dryer. Air from your house soaks up warmth as it goes by the heated burner. That air is after that dispersed to spaces in the residence by means of the air ducts. While fairly straightforward, trusted, as well as risk-free, resistance home heating is usually thought about a much less reliable as well as extra costly method to heat up a house.

Heatpump, either air-source or geothermal, are one of the most effective means to warm and also cool with electrical energy. Air-source heatpump are one of the most typical, and also make use of a cooling agent or chemical to soak up warmth from the air outside the residence, focus it, as well as utilize the focused warmth to heat the house. While rather reliable, air-source heatpump could shed effectiveness as the outdoors air obtain extremely chilly. Geothermal utilizes heat from the planet for the exact same objective. Considering that geothermal systems make use of warmth from the ground, it's unsusceptible to the really winter inadequacy that air-source heatpump experience.

Air conditioning

Air conditioning is attained by means of the electrical air-conditioner (or cooling cycle of the heatpump). Refrigerant gas (even more frequently recognized by the brand name, Freon) is pressed by a compressor right into a high pressure gas. The compressor pumps the high pressure gas with a radiator-like condenser coil of copper (or in some cases light weight aluminum) tubes and also light weight aluminum fins where a big follower transfers warm to the outdoors. This is all achieved in the outside part of your air-conditioning devices. Next off, the cooled down, pressed, cooling agent fluid is pumped right into your home using the copper tubes, getting to the additionally radiator-like evaporator coil. There, under much less stress, it evaporates from a fluid to a gas again. An all-natural residential or commercial property of this modification from fluid to gas is that the cooling agent soaks up warmth quickly from the air being blown via the evaporator by the blower. The cooled down air is distributed with the residence through the air ducts. The cooling agent gas after that goings back outdoors to the compressor, where the cycle begins again once more.

Part of our pain in the summer season originates from high moisture airborne makings us really feel sticky or clammy. So, at the same time the air in your house is being cooled down by your air-conditioner, it's additionally being dried out. The blower attracts cozy, damp air from the house with return air ducts as well as throughout the evaporator. Moisture from the cozy, wet air condenses on the amazing evaporator coil as fluid water, leaking right into a drainpipe frying pan listed below. The air leaving the evaporator is after that not just cooler, yet drier. That's why we call it "air-conditioning" as well as not simply "air-cooling.".

Air flow.

Inning accordance with the EPA, interior air is 5 times extra polluted compared to outside air. As a culture, we're investing a growing number of time inside - as long as 90% of our time, by some price quotes. That's why interior air top quality (IAQ) is being linked in health issue from bronchial asthma to cancer cells. An air filter could strain big bits, yet fumes from cleaning up items, paints, furnishings, as well as various other resources could off-gas unstable natural substances (VOCs) which could adversely influence our wellness. These are harder to filter from interior air, so they ought to be ducted to the outdoors.

Significantly, mechanical air flow is being incorporated right into the HVAC system to eliminate stagnant air from inside a house and also generate fresh air from outdoors. This can be as basic as a collection of air ducts with followers on timers which tire stagnant interior air as well as generate fresh exterior air. A system like that, nonetheless, wastes power. That's why lots of more recent houses as well as remodels are utilizing Warm Recuperation Ventilators (HRVs) and also Power Healing Ventilators (ERVs). These home appliances connect to the existing air duct system and also include an exhaust air duct as well as a supply air duct to the outdoors. After that, the devices wear down stagnant air from the residence and also generate fresh air from outside the residence, yet pass both jet stream with a power healing tool which removes the cooling or heating power in the outbound stagnant air. That power is after that entered the inbound fresh jet stream, decreasing power loss by approximately 95% while still supplying fresh air. Numerous mechanical air flow systems likewise consist of air filters to eliminate dirt as well as irritants from inbound air.

Upkeep Tips for Your HVAC.

Maintain your HVAC financial investment in great form for optimum convenience, power performance, and also long running life:.

· Adjustment the blower filter a minimum of two times a year-- when prior to the home heating period as well as soon as prior to the air conditioning period. More frequently if you stay in a much more messy location.

· Maintain parts tidy, particularly the outside condenser/compressor device. Get rid of dust & particles, as well as reduced plants a minimum of 2 feet on all sides.

· Make use of a programmable thermostat: When you're far from house or in the evening when resting, permitting the temperature level to drop (in the wintertime) or surge (in the summertime) by 10 levels for 8 hrs or even more could conserve 5% -15% on heating and cooling prices. With a heat-pump, nonetheless, just utilize this pointer throughout the summer season, as the heatpump's home heating cycle is extra reliable when left at a stable temperature level.

· Have your HVAC system serviced by an experienced professional yearly. While there are cleaning up jobs that a lot of house owners could achieve, various other jobs, like inspecting burning in gas or oil heaters or guaranteeing there are no leakages in a cooling agent line, are best entrusted to specialists.

· Shield and also air-seal your house effectively-- HVAC tools is far more effective if the residence's covering is effective. (for a do it yourself overview, have a look at this set from EnergyStar.gov.).

· When preparing for a brand-new HVAC system, whether mounting for the very first time or changing an old system, urge that the HVAC professional do extensive "Hands-on J" estimations to determine the system dimension. Equipments that are either also little or as well huge will certainly not run successfully, supply bad convenience, not effectively deal with the residence's moisture requirements, and also will likely stop working earlier compared to needed.

· In any type of residence, despite whether gas or oil is made use of for HVAC or various other functions, set up and also keep smoke and also carbon monoxide gas alarm systems for your family members's security.

· If you warm as well as cool with power, take into consideration updating to geothermal heating and cooling. These systems set you back a little bit extra in advance, however they last as much as two times as long as air-source heatpump, run even more silently, and also conserve loan on power expenses. As an alternative in these systems, waste warm produced by the air-conditioning cycle in the summertime can be utilized to warm your residential warm water absolutely free.

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