biohackerblogger-blog

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Want to get ahead in life and live forever? Biohack your brain and body today!!

Welcome back reader. My previous blog discussed what biohacking is and some aspects of human biology that can be tweaked to great returns. Biohacking is basically tweaking your biology to improve your life.

In my self-improvement adventures I use scientific research to justify whatever changes I make to my lifestyle whenever I can. If the science says something shows promise in improving x, y and z—I test it out for myself and if it works, I keep it. I’ve found that Reddit, the popular discussion platform, is a great place to find aggregations of links to relevant literature and is in of itself a repository of anecdotal evidence.

As promised, I’m going to be going more in-depth into my personal biohacking experience in this article, talking about the specific improvements I’ve made to better myself and the scientific justifications behind them.

Supplementation

My primary goal mentioned in my previous blog was optimising cognition. Supplementation seemed like a good way to tackle this issue.

To begin, I started with the basics. Well-researched, basic micronutrients that many people lack in their diets and provide clearly defined improvements. I went to the lab near my house and got bloodwork done, testing for everything (Thank you Belgian insurance).

Omega 3/6 Fatty Acids

These are one of the most well-researched, beneficial classes of molecules that are lacking in our diets today. Alpha-linolenic acid (ALA), found in plant oils such as flaxseed and canola, is an essential fatty acid—meaning your body cannot synthesize it independently so it needs to come from your diet. Eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) (found in fish) can be produced by conversion of ALA but in minimal amounts—so practically you’re better off getting these from your diet/supplement also.

Omega acids are a critical component of the membranes that make up the surface of each of your cells. They regulate the fluidity of these membranes, the signaling between cells and also maintain cell structure. They’re also involved blood pressure maintenance, the nervous system, regulating inflammation and have been linked to the prevention of alzheimer's (so cognitive benefits too). This study goes more in depth as to the physical benefits these molecules provide.

People don’t eat enough fish especially in western diets to get enough of these on a daily basis so I would strongly recommend a supplement—this is the one I get. The ratio between the amount of omega-3 to omega-6 is also important and is discussed in this study.

Vitamin D

Our skin produces its own vitamin D when exposed to sunlight regularly. A problem with living in a northern country like England is that there’s not a whole lot of sunlight to go around. This isn’t helped by the fact that we’re not naked cavemen anymore who stand outside all day in the sun. Vitamin D is important for calcium absorption into the bones which is why a deficiency can cause malformations such as rickets. Deficiencies can also cause depressive symptoms and exacerbate mental health issues. Decreased sunlight during winter can also increase the incidence in a temporary depressive disorder known as seasonal affective disorder (also known as SAD—ironic, I know). Light therapy has proven an effective way of increasing vitamin D and treating SAD.

I take it on the reg to stave off the winter blues as a supplement-if I’m happier my brain is happier too. When possible, Vit D from sunlight is a much better source than from a supplement. This is the one I take.

Vitamin B complex

B vitamins consist of 8 different vitamins. B12 is likely the most well known and is involved in neurological function and production of DNA. B9 regulates cell division and formation of blood cells. Each vitamin has specific roles in the body that a deficiency could significantly interfere with. Natural sources are typically animal products and high protein plants.

You can conveniently get supplements that contain all 8 in one which simplifies things immensely. They have been linked to reduction of stress, anxiety and depression and I thought that would be of use to me. I take this one.

Zinc, Magnesium, Calcium and others

Each mineral has a different purpose when it comes to human health but all are important. Zinc plays roles in immune function, DNA synthesis, inflammation and much more. It also boosts testosterone, a hormone providing many health benefits for men (and some for women) that I touched upon in the previous article.

Magnesium can significantly improve your sleep if you get enough of it (and good sleep just improves everything) and calcium is important for bone health. These are all very important micronutrients so make sure you’re getting enough in your diet or supplement them.

Probiotics

You know those icky bacteria lining every inch of your body and intestines? What if I told you that they actually affect your life a whole lot more than you think—Especially your mood.

Research into the gut microbiota (community of microorganisms in the gut) is an incredibly hot topic right now. The presence or lack thereof of certain bacteria in the gut can affect your digestion, risk of developing diseases, even your position on the autism spectrum. It sounds crazy but the research is substantial. Many digestive problems and others can be solved by rectifying the ratios of different bacteria in the gut, by introducing healthy bacteria. I’ve tagged along to a couple of conferences with my psychiatrist mother discussing the interaction between the gut microbiota and health (physical and mental) and have also had several assignments on the topic during my time at university.

I now take a probiotic supplement every morning. Probiotics are basically pills containing millions of live, healthy bacteria.

Creatine

This one maybe isn’t as important for most people but I’ll mention it because it’s part of my daily regime. It’s a very well-researched supplement used by athletes to increase performance by increasing water retention in the muscles. With the added benefit of making your muscles look bigger, creatine can improve strength and endurance during sport. I take it to improve my workouts which itself benefits my life. Optimum Nutrition has some really good products, I go with them. Here’s another review article if you’re interested.

Other cognition-enhancing compounds

(I’m not recommending anyone take any of the following as I am not qualified to be giving out advice on scarcely researched compounds but hey, if you do your own digging, decide the science is sound and there’s no risk, you do you.)

Described above are the supplements I use to benefit my life currently. They are all well-researched staples with plenty of studies to support their efficacy. There are, however, less researched compounds that could be potentially beneficial that are hidden from the public eye.

There exist a number of alternative medicines like St. John’s Wort to treat depression that can have beneficial effects on health. Some medicines are alternative for a reason, we don’t really know enough about them to know how they work but we just know that they do for the most part.

Withania somnifera (Ashawagandha) is a herb that reduces stress and has anxiolytic (anxiety reducing) properties by reducing cortisol, the stress hormone. It’s also implicated in helping with neurodegenerative diseases such as Parkinson's, Huntington's and Alzeimer's disease but more large scale studies are needed to prove it’s therapeutic potential. Lion’s mane mushroom is another cool one thought to also help with cognition that I’ve been looking into recently

Nootropics (cognition enhancing compounds) are quite popular in the biohacking community. Many people take so-called “stacks” of supplements that synergize and work well together. A simple example of a stack would be taking L-theanine and caffeine, (caffeine is the most well-known nootropic) where the caffeine works to give you energy and the L-theanine smooths out the “edge” of caffeine, eliminating the crash you get.

This is gonna be an iffy one to talk about in a uni assignment but I already gave my disclaimer at the top of this section. Microdosing is an increasingly popular trend popularized by big innovators such as Steve Jobs and Bill Gates—It involves taking sub-perceptual doses of psychoactive compounds.

Psychedelics such as LSD and MDMA have become very hot topics of research particularly in the psychiatric field. There is an increasing amount of evidence to suggest their utility in treating addiction, depression and anxiety when paired with psychotherapy. Psychedelics have a very impressive safety profile despite the bad rep they get.

David Nutt, a prominent researcher into the field collated the answers of a panel of experts (from law enforcement to doctors) to attempt to objectively rank common drugs in terms of addictive potential and harm. LSD and Ecstasy are significantly less harmful than the legal substances tobacco and alcohol. The 2017 Global Drug Survey also supports this claim.

Don’t get me wrong, there are some risks to psychedelics if used irresponsibly (such as triggering the onset of schizophrenia in those genetically predisposed to it) but overall, they have untapped potential in research as they significantly increase brain plasticity (ability of brain to adapt and change) and connectivity of neural networks. Microdosing them can increase productivity/creativity and allow the formation of novel neural pathways (which is probs why they help with addiction). I was actually considering psychedelic research as a career path as lots of big names like John Hopkins University are heavily involved in research into the field.

Anyway, some may say that all these supplements are a bit excessive, and maybe they’re right. But I say eh, works for me.

Habits and Lifestyle changes

I discussed the benefits of meditation in my last blog already but that is a very useful meta-tool for improving on all aspects of life. There are small ways we can all change our environments to improve our lives depending on our goals.

Procrastination in particular is a huge issue that many people face, students in particular. Many people struggle to understand why we do this but they aren’t aware that our biology isn’t designed to be able to cope with the huge amounts of stimuli that have arisen from the invention of the internet and social media. It’s now well-known that willpower functions similarly to a muscle—we don’t have an unlimited supply of it, it can get tired. What we can do to get around that is reduce the need to strain that muscle by changing our environment.

I’ve personally deleted all forms of social media I’ve found to not contribute anything meaningful to my life and with the rest I’ve unfollowed/unsubscribed to anything I thought would distract me too much. When studying, I use earplugs to block out as much stimuli as possible and I keep my phone off for most of the time.

This is what my phone’s home screen looks like:      

Simple, practical, not distracting. All the distracting applications like social media are kept on a different screen so I have to put in more effort to get to them. My phone’s also in greyscale but the screenshot doesn’t pick that up. Greyscale removes all the bright colors from your phone screen, significantly reducing the addictive potential of your phone. If you find yourself checking your phone too often, this might help you out.

This article from lifehacker talks about it in more detail. Many phone manufacturers have rolled out updates to help people curb their screen time, adding options to put time limits on your apps and overall screen time.

These are only some of the small changes I’ve implemented.There’s plenty of things you could be doing to make your environment facilitate your goals, you just have to be a bit creative.

That's pretty much an overview of my personal experience with biohacking. I hope you found this interesting and informative and it inspired you in some shape or form to read into science more and improve your life in every way you can.

Thanks for reading,

Alex

Stock images all courtesy of google images

Supplements:

Omega acids -

https://www.amazon.co.uk/gp/product/B004MASMXG/ref=ppx_yo_dt_b_asin_title_o06_s00?ie=UTF8&psc=1

Vitamin D -

https://www.amazon.co.uk/gp/product/B072L235Z5/ref=ppx_yo_dt_b_asin_title_o09_s00?ie=UTF8&psc=1

Vitamin B Complex -

https://www.amazon.co.uk/gp/product/B00Z70OUQS/ref=ppx_yo_dt_b_asin_title_o06_s00?ie=UTF8&psc=1

[biohackerblogger-blog]

Biohacking and Science: A solution for most of your problems

In this article I’m going to be discussing biohacking—what it is and the different aspects of human biology an individual can improve (or “hack”, if you want to call it that) to optimise their life and cognition. In the next blog I’ll discuss the specific improvements I’ve made in my life and their scientific justifications—with an in-depth focus on nutrition, supplementation and cognitive-enhancement.

Biohacking as defined by merriam-webster is “biological experimentation done to improve the qualities or capabilities of living organisms especially by individuals and groups working outside a traditional medical or scientific research environment”.

While that sounds dramatic, the term could also be described as do-it-yourself biology—making small, incremental changes to your diet, habits and life to optimise your cognition and life expectancy. This hobby likely originated in Silicon Valley, a place popular in many trendy self improvement hacks: The keto diet, intermittent fasting and microdosing to name a few.

We are living in an era of excess. Western supermarkets are packed full of processed, sugary, fatty products that people cling to as comfort food. Social media and smartphones have been tweaked to be as addictive as possible. Even television has been replaced by on-demand streaming services that provide countless hours of mindless oblivion to addicted viewers—so much so that “binge-watching” is now a recognized term in many dictionaries. This combination and more has led to the shortening of the average attention span.

Coincidentally, it feels like every other person in recent generations seems to suffer from some form of ADHD, depression or other mental health issues.

Me, technically a part of generation z, am no exception.

I’ve been an underperformer most of my school career, with every parent-teacher meeting ending the same way: “Alexandru is a very bright boy but he doesn’t seem to be reaching his potential in class.”

I daydreamed, lost focus often and was often unmotivated when tackling complex tasks. My mom has practiced psychiatry for 2 decades and during my last year of high school I saw one of her colleagues who eventually diagnosed me with ADHD.

This shook me. I had believed that I was just a lazy person, not working hard enough but now this doctor was basically telling me that it wasn’t my fault; That I had a learning disability that would always put me at a disadvantage to other “functional” people.

As I made my way through university the same issues kept coming up over and over again and I started feeling hopeless. Medication seemed to act as a bandaid on the problem, working as intended inconsistently. Is this what the rest of my life was gonna be like?—Craving achievement while lacking the motivation to acquire it?

Nahhhh, I wasn’t going to let some abstract diagnosis prevent me from prospering in life.

Enter biohacking:

In my spare time at uni I began researching ways of “curing” my ADHD. The goal: Improving my attention, motivation and cognition anyway I could. I’m a scientist, so it only made sense to solve my problems with science. Little did I know I wasn’t so much as curing a disorder as I was just finding ways to optimise my life using scientific knowledge. I tried different lifestyle changes and recorded the positive benefits of each one—Basically running my own scientific experiments on a sample size of 1. Biohacking is basically tweaking your biology to improve your life.

Diet

As I mentioned before, supermarkets today are full of horrible, delicious processed food. It’s expensive eating healthy and it’s difficult to resist the allure of a greasy portion of chips. Regardless, I think a large percentage of the population seriously underestimate how much your diet impacts your day-to-day life as a human being. A heavily debated study found that judges tended to give harsher sentences just before lunch due to hunger (This study has argued about for years). If even people who practice being impartial for a living are at the mercy of their own biology—that means so are you.

Your body is a complex machine, requiring certain amounts of macronutrients (protein, carbs, fats) and micronutrients (vitamins, minerals) to carry out all of it’s processes efficiently. If any of these numbers are skewed, the machine won’t run smoothly. You can optimise your diet in a number of ways depending on your goals, but the FDA and similar organizations provide recommendations as to how much of each nutrient an average individual requires in a day.

Many of the micronutrients have important roles in our day-to-day lives which becomes apparent when we are deficient. Magnesium plays a huge role in good-quality sleep while vitamin D is important for healthy bones and mood. The world health organisation provides guidelines for what they consider a healthy diet which contains healthy doses of all these nutrients. Obviously, we’re human, not superhuman and we can’t always have a perfect diet all the time. There’s no shame in supplementing your diet artificially, just don't use pills as a replacement for healthy eating habits. Getting blood work done can help you identify which vitamins and minerals you're deficient to inform your dietary changes or supplement purchases.

If you're looking to improve cognition, omega-3 fatty acids are a well-researched staple supplement that is found in high quantities in fish. I could write a whole article on cognitive enhancement and supplements—so I’ll save it for the next one.

If weight loss is your goal maybe consider reading up on the science of the keto diet (a fat heavy diet that pushes metabolism into burning fat) or experimenting with alternative eating habits like intermittent fasting. Hell, I hear great things about going vegan nowadays and you’d be saving the environment while you’re at it.

Play around with it, optimise it for your goals and give supplements a try.

Exercise

The NHS recommends 75-150 minutes of exercise a week for the average individual. Obesity continues to be a huge issue in this country and others so more still needs to be done to encourage public fitness. It seems that many people make the mistake of thinking of exercise as a distraction from more important things like careers and making money, especially as they get older. They say they’re simply too busy and can’t find the time but in reality they’re decreasing their potential to excel in other aspects of their lives. There’s no point in making money if you’re too fat and achy to enjoy spending it.

Exercise is important. As Socrates eloquently puts it:

“No man has the right to be an amateur in the matter of physical training. It is a shame for a man to grow old without seeing the beauty and strength of which his body is capable.”

Deep.

Endorphins produced by exercise  make us feel great, we sleep better, we have more energy, we are more engaged with our work—Not a whole lot of downsides. For men in particular weight training is a very well-researched method or raising testosterone levels. A hormone my generation seems to be in significant lack of but in need of due to its important properties. Testosterone has anxiolytic properties, lubricates social interactions and is involved in providing an array of physical health benefits too.

Exercise is free, there are no downsides and a plethora of benefits. It doesn’t so much matter what type of exercise you’re doing so much as you’re doing it on a regular basis. It will suck, especially if you’re not accustomed to regular exercise but once you make it a habit (takes around 21 days to make something a habit), you’ll stop thinking about it and it’ll happen automatically.

Biohacking sure sounds a lot like self-improvement eh?

Sleep

In today’s day and age a good night’s sleep has become a rare treat. It’s like taking a gamble every night and hoping you wake up rested. As a student studying in the UK, I feel like I’m probably the most qualified person to say that. Sleep is very important for humans as pretty much all of our physical processes are regulated to some extent by our biological clock. A clock set by our circadian rhythm (Aka sleep cycle). Small perturbations to our sleep can seriously knock our daily rhythm out of line. Memories are written into your long term memory, waste products are flushed from the brain and the body readies itself for the new day. Everyone is aware their performance drops after a poor night’s sleep.

Here are some things you can do:

Humans need to go through about 4-6 sleep cycles per night to function adequately.

                          Sleep cycle = 90 minutes +/-                  5 * 90m = 7.5 hours

Try to wake up after sleeping a multiple of 90 minutes. If you wake up during the middle of a cycle you’re more likely to feel groggy. 6 hours, 7.5 or 9 hours between bed and wake are what you’re looking for.

Avoid blue light before bed. I’m sure you’ve already heard this one but blue light from screens inhibits sleep. Try a blue light filter on your laptop—Flux is the free one I use and recommend.

Avoiding caffeine, sugar and carbs before bed works wonders for your sleep. A magnesium supplement does too.

Going to bed and waking up at the same time consistently will make sleeping easy and soon your whole body will adjust itself to the routine. The human body loves routine.

Anything else worth mentioning

Yes, meditation is a big one. Specifically mindfulness. If you haven’t already been preached to on the internet about the numerous benefits of meditation, it seems to improve pretty much everything about people.—The ultimate meta-habit for improving all aspects of living. It shows promise in ameliorating depressive symptoms, anxiety, self-control and a lot more.

The mobile app headspace provides a great starting point and for those that want a challenge and want to try their hand at a monk’s life check out Vipassana meditation. Their free week-long retreats are a crash course in mindfulness with lifelong benefits. I tried one this summer and was convinced it was a cult for the first 3 days.

I’ve seen huge improvement in my life after I started applying science to fix my problems. I hope I’ve managed to give an effective overview of my experience in biohacking and given you some well-researched places to get started. If you have a biological background I think it’s a shame not to use that background to optimise your life in every way you can.

Thanks for reading,

Alex

P.S. here’s a short rant:

I think (not all, but a lot) of the recent diagnoses of ADHD and depression could be “cured” by not treating it as an isolated malady caused by some bad genes and poor luck—but as a culmination of lifestyle choices and habits that could be improved upon. Exercise and diet should be the FIRST CHOICE intervention when it comes to treating things like ADHD and depression.

I believe diet and exercise should always precede a chemical solution to these ailments. There are hundreds of supplements and activities that have proven psychological benefits that could hugely benefit humans. Thanks again.