cfsremission

[cfsremission]

Discussion with a Long COVID patient on using Microbiome Prescription

Today I had a nice 70 minute discussion with a user. This shows pretty much all of the new features and options for building your own plan. This applies also for ME/CFS. In fact, the top forecasted symptom for him was ME/CFS without IBS. He has no IBS. Issues are discussed on many choices.

[cfsremission]

Reviewing recent study on Fibromyalgia

This is based on this April 24,2035 paper: The gut microbiota promotes pain in fibromyalgia. There are two interesting finings: “transplantation of a healthy microbiota [FMT] is associated with reduced pain and improved quality of life. ” This option is rarely available since FMT is only authorized for  recurrent Clostridioides difficile infections And  “Since mice transplanted with the FM gut…

[cfsremission]

Virus, Microbiome and ME/CFS - a connected story

When it comes to virus and ME/CFS there are several schools of belief. A Virus caused ME/CFS and thus eliminating the virus should cause remission Virus are re-activated (or no longer suppressed) by the immune changes associated with ME/CFS De-activating the virus may improve (but not cure) ME/CFS Past Posts on Virus EBV, HHV5 and other virus in CFS [2016] Viruses, Retrovirus and Chronic…

[cfsremission]

Comparing AI Answers on ME/CFS Microbiomes

My focus for the last few years has been on the ME/CFS Microbiome. I decided to test a variety of AI sites for their answering of the question below. Why do I ask this question? Simple, the rate of ME/CFS is very different between men and women, hence the differences of the microbiome may account for this. What is the difference of reference ranges between 30 year old men and women…

[cfsremission]

CFS, Long COVID and progress!

This is part of a series on Analysis Posts on Long COVID and ME/CFS Back Story I’d love some additional help, please. I’ve done two BiomeSight.com tests. I followed the suggestions after the first test and my microbiome has changed and some of my symptoms are improving. However, I couldn’t tolerate any of the bifidobacterium strains I tried, all of them caused very painful long-lasting…

[cfsremission]

Your next symptom?

First, apologies to people over the microbiome prescription site being up, then down, then up, then down. The hosting company that I am using (and 900,000 other customers!) having been dealing with issues with their cloud provider. As I write this on Saturday, March 8th 2025, evening — it is back up. Today, I reworked some old page concepts, improving the mathematics and the presentation. The…

[cfsremission]

Bacteria Associated with ME/CFS

For any one that is interested, bacteria with P < 0.005 significance to 324 symptoms and diagnosis is now available (with source data) at https://microbiomeprescription.com/sample/FrequencySome items of interest to the ME/CFS Community are below

[cfsremission]

Metabolites [Enzymes] and ME/CFS

In my last post on MRI Scans, I felt the best model is based on Evidence of widespread metabolite abnormalities in Myalgic encephalomyelitis/chronic fatigue syndrome: assessment with whole-brain magnetic resonance spectroscopy [2020]. Metabolite abnormalities can be a direct result of microbiome dysfunctions. Those abnormalities are very treatable using microbiome tests and expert systems such as…

[cfsremission]

Update on ME/CFS Brain Scans: Part 1 - MRI

This is an update of my post from 10 years ago, CFS: Appropriate Brain Scans. I will focus on studies in those 10 years. Short version of these studies below. Data showed that MRI studies frequently reported structural changes in the white and gray matter. Abnormalities of the functional connectivity within the brainstem and with other brain regions have also been found. The studies have…

[cfsremission]

Bacteria Shifts that are Statistically Significant for ME/CFS

The process is very simple, for a condition like ME/CFS, we compute the expected number of samples reporting this bacteria (based on people without Long COVID) and compare it to the actual number seen. This can be used to compute a statistical value called Chi-Square (χ²), This is then used to compute the chance of it happening at random. This is possible because we have over 3600 samples from…

[cfsremission]

An Affordable Smartwatch for ME/CFS?

Recently I have seen advertisements for smart watches for ME/CFS. The price would be challenging for many people. I suspect that it also has a poor return for the costs. This post is about the watch family that my wife and I have been using for a few years. The current version is below. On occasion, I have seen the price under $20.00 People who know me, knows that I prefer to work off objective…

[cfsremission]

Statistically Significant Bacteria shifts seen in ME/CFS

Statistics is fun because there many paths. Most studies using the microbiome uses the easy, but naïve, path of computing averages and standard deviation. As my dataset has grown, I have been travelling some less traveled path, for example: Visual Exploration of Odds Ratios, and a patent pending method termed “Kaltoft-Moltrup”. One of the frequent decisions that I see in studies is to limit…

[cfsremission]

Visual Exploration of Odds Ratios

This is a “scribe notes” post. I am working on implementing odds ratio as a forecaster for ME/CFS and encountered some issues. In my work experience, this means taking a significant step backwards to look at the data better. I will look at the bacteria with a high frequency of being reported in tests first. The genus of greatest interest from preliminary work…

[cfsremission]

ME/CFS: The Evils of Lactobacillus Probiotics?

A reader wrote me today with the following question I read your article on microbial involvement, can you explain in more detail why you recommended cutting out Lactobacillus? If I interpreted your analysis, you said lactobacillus was rare in ME/CFS, doesn’t that mean increasing it could be beneficial? “..lactobacillus shows up barely in only one result..”.Meaning lactobacillus is rare for…

[cfsremission]

Odds Ratios for Metabolites and ME/CFS

This post extends the analysis of microbial involvement in ME/CFS pathophysiology by focusing on metabolites produced or consumed by bacteria, rather than on individual bacterial species seen in the earlier post Microbial involvement in myalgic encephalomyelitis/chronic fatigue syndrome pathophysiology. . This shift in perspective is valuable because: Metabolite-Centric Analysis Bacterial…

[cfsremission]

Microbial involvement in myalgic encephalomyelitis/chronic fatigue syndrome pathophysiology

This is the title of a new publication in Microbes & Immunity, available here. Microbiome fluctuations or metabolic endotoxemia are proposed as possible disorder biomarkers. Based on the fact that gut microbiota dysbiosis reverts to a state of eubiosis in long-term patients with this condition, it may be hypothesized that disease progression begins with the loss of beneficial gut microorganisms,…

[cfsremission]

ME/CFS Patient continues the trek to recovery

Prior Posts Dealing with ME/CFS and many microbiome dysfunction is rarely a short journey ME/CFS Continues Improvement + Lab Read Quality Issues [Feb 2024] Update on ME/CFS Person [Sep 2023] Follow up Microbiome Analysis from a prior post [Apr 2022] Rosacea, Circulation and mild CFS [Dec 2021] Recent Story Some supplements that I have been taking since the last…