hihelloheyyyy

[hihelloheyyyy]

[hihelloheyyyy]

Been getting really into orange juice lately

[hihelloheyyyy]

[hihelloheyyyy]

[hihelloheyyyy]

"The first modern attempt at transferring a uterus from one human to another occurred at the turn of the millennium. But surgeons had to remove the organ, which had become necrotic, 99 days later. The first successful transplant was performed in 2011 — but even then, the recipient wasn’t immediately able to get pregnant and deliver a baby. It took three more years for the first person in the world with a transplanted uterus to give birth. 

More than 70 such babies have been born globally in the decade since. “It’s a complete new world,” said Giuliano Testa, chief of abdominal transplant at Baylor University Medical Center.

Almost a third of those babies — 22 and counting — have been born in Dallas at Baylor. On Thursday, Testa and his team published a major cohort study in JAMA analyzing the results from the program’s first 20 patients. All women were of reproductive age and had no uterus (most having been born without one), but had at least one functioning ovary. Most of the uteri came from living donors, but two came from deceased donors.

Fourteen women had successful transplants, all of whom were able to have at least one baby.  

“That success rate is extraordinary, and I want that to get out there,” said Liza Johannesson, the medical director of uterus transplants at Baylor, who works with Testa and co-authored the study. “We want this to be an option for all women out there that need it.”

Six patients had transplant failures, all within two weeks of the procedure. Part of the problem may have been a learning curve: The study initially included only 10 patients, and five of the six with failed transplants were in that first group. These were “technical” failures, Testa said, involving aspects of the surgery such as how surgeons connected the organ’s blood vessels, what material was used for sutures, and selecting a uterus that would work well in a transplant. 

The team saw only one transplant fail in the second group of 10 people, the researchers said. All 20 transplants took place between September 2016 and August 2019.

Only one other cohort study has previously been published on uterus transplants, in 2022. A Swedish team, which included Johannesson before she moved to Baylor, performed seven successful transplants out of nine attempts. Six women, including the first transplant recipient to ever deliver a baby back in 2014, gave birth.

“It’s hard to extract data from that, because they were the first ones that did it,” Johannesson said. “This is the first time we can actually see the safety and efficacy of this procedure properly.”

So far, the signs are good: High success rates for transplants and live births, safe and healthy children so far, and early signs that immunosuppressants — typically given to transplant recipients so their bodies don’t reject the new organ — may not cause long-term harm, the researchers said. (The uterine transplants are removed after recipients no longer need them to deliver children.) And the Baylor team has figured out how to identify the right uterus for transfer: It should be from a donor who has had a baby before, is premenopausal, and, of course, who matches the blood type of the recipient, Testa said...

“They’ve really embraced the idea of practicing improvement as you go along, to understand how to make this safer or more effective. And that’s reflected in the results,” said Jessica Walter, an assistant professor of reproductive endocrinology and infertility at Northwestern University Feinberg School of Medicine, who co-authored an editorial on the research in JAMA...

Walter was a skeptic herself when she first learned about uterine transplants. The procedure seemed invasive and complicated. But she did her fellowship training at Penn Medicine, home to one of just four programs in the U.S. doing uterine transplants. 

“The firsts — the first time the patient received a transplant, the first time she got her period after the transplant, the positive pregnancy test,” Walter said. “Immersing myself in the science, the patients, the practitioners, and researchers — it really changed my opinion that this is science, and this is an innovation like anything else.” ...

Many transgender women are hopeful that uterine transplants might someday be available for them, but it’s likely a far-off possibility. Scientists need to rewind and do animal studies on how a uterus might fare in a different “hormonal milieu” before doing any clinical trials of the procedure with trans people, Wagner said.

Among cisgender women, more long-term research is still needed on the donors, recipients, and the children they have, experts said.

“We want other centers to start up,” Johannesson said. “Our main goal is to publish all of our data, as much as we can.”"

-via Stat, August 16, 2024

[hihelloheyyyy]

[hihelloheyyyy]

yeah im “transitioning” *dissolves into tiny pieces as i click to the next slide*

[hihelloheyyyy]

Posting all of the pills that make you green comics here now, enjoy? I guess?

regret rates

proof

talking points

you problem

owned

modern invention

unethical experiments

typology

think of the children

side effects

facts

making sense

rushing

drawings

research

this rocks

valid

Next

[hihelloheyyyy]

thank god im aromantic. i think everyone should get more aromantic

[hihelloheyyyy]

terfs would lose their minds if they were exposed to 2000s-2010s "a girl can do anything a boy can do, including beating them at sports" messaging like why are you all acting like nobody has ever said this and that it's radical to think that women aren't inherently worse at things. open your mind. read some feminist theory. touch some grass. the most basic banal middle-class white woman feminism of the 2010s looks fucking radical and visionary compared to the misogynistic victimization complex y'all are peddling

[hihelloheyyyy]

this is so real, and I feel like no one ever talks about it. I love watching anime and I like to turn on the dub along with the subtitles since just reading the subtitles. It’s hard for me to keep up with, but just listening to the dub. It’s hard for me to hear the combination of them is very helpful for me to understand what is being said. What I’ve noticed for a lot of anime dubs is that they’ll use the subtitles for the other language that it’s in, but they won’t subtitle the English dub. It’s very disorienting and it takes me a lot longer to understand what’s going on in a show. This doesn’t just go for anime, but any show that has an English dub. Almost every time the dub will not have its own subtitles and since the dub can’t always follow the direct translation of the original audio, the words are going to be different in the subtitles so when they use the subtitles for the original audio on the dub, the words do not lineup. There have been times where the subtitles will tell a completely different story than what the dub tells. It’s one of the most frustrating things for me while watching a foreign show and makes them very inaccessible. 

happy disability pride month and once again, FUCK lazy subtitles. fuck the [speaks foreign language] instead of actually transcribing the words, fuck shortening sentences and changing whats been said for no reason, fuck censoring swearing in captions but not in audio and fuck anyone who says youre being 'too sensitive' for being upset about a lack of accessibility

[hihelloheyyyy]

happy disability pride month and once again, FUCK lazy subtitles. fuck the [speaks foreign language] instead of actually transcribing the words, fuck shortening sentences and changing whats been said for no reason, fuck censoring swearing in captions but not in audio and fuck anyone who says youre being 'too sensitive' for being upset about a lack of accessibility

[hihelloheyyyy]

[hihelloheyyyy]

i cant believe that there's still gamergate STANK on games that women enjoy. NASTY misogyny residue. stardew valley is in fact a video game. animal crossing is also a video game. so are otome games and dating sims and twee little cozy games. sometimes a bitch doesnt wanna play bloodborne that shit's hard

[hihelloheyyyy]

cure of ra

[hihelloheyyyy]

Have a Good Morning ever day forever no matter what!!!

[hihelloheyyyy]

I know this is going to make me sound pretensions but I have to get it off my chest. I feel an unimaginable rage when someone posts a photo and is like "this picture looks like a renaissance painting lol" when the photo clearly has the lighting, colors and composition of a baroque or romantic painting. There are differences in these styles and those differences are important and labeling every "classical" looking painting as renaissance is annoying and upsetting to me. And anytime I come across one of those posts I have to put down my phone and go take a walk because they make me so mad