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Ethnicity, Alcohol Dependence, and Liver Health: A Revealing Association?

I am French-speaking.

Dataset Selection

For this project, I chose to use the NESARC Wave 1 dataset (National Epidemiologic Survey on Alcohol and Related Conditions). It is particularly relevant because it includes:

Detailed demographic information (race, ethnicity, income, age, etc.),

A DSM-IV diagnosis of alcohol dependence,

Medical data including history of liver and heart diseases.

Research Question and Hypothesis

Research Question:

Is there a link between ethnicity, alcohol dependence, and the prevalence of liver disease among Americans aged 17 and older?

Hypothesis:

I believe that alcohol dependence is strongly associated with liver disease risk, and that this risk varies by ethnicity.

In particular, individuals of Hispanic or European descent with high alcohol dependence are more likely to develop liver disease than those of African American descent.

Literature Review

Identified Scientific References (2 points)

Grant BF et al. (2004) – Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders. ➤ Archives of General Psychiatry, 61(8):807–816 ➤ DOI: 10.1001/archpsyc.61.8.807

Rehm J, Roerecke M. (2013) – Alcohol use and risk of liver cirrhosis: a systematic review and meta-analysis. ➤ American Journal of Gastroenterology ➤ Shows a dose-response relationship between alcohol and cirrhosis.

Chartier K et al. (2016) – Ethnicity and health disparities in alcohol research. ➤ Alcohol Research: Current Reviews ➤ Examines ethnic differences in the health impacts of alcohol use.

Summary of Findings and Variables Considered:

Chronic alcohol use and alcohol dependence are causally linked to liver diseases (including steatosis, alcoholic hepatitis, and cirrhosis).

Significant differences across ethnic groups have been observed in the prevalence and treatment of these conditions.

The conceptual model of this project plans to test an interaction effect between ethnicity and alcohol dependence on liver disease risk, while controlling for age and income.

Personal Codebook

S1Q1E, S13Q6A9, S13Q6B9, S13Q6A7, S13Q6B7, S13Q6A8, S13Q6B8

✅ Conclusion

Through this project, I aim to highlight the link between biological and social factors (ethnicity, alcohol dependence) and a major public health issue: liver and heart disease. It is based on a robust dataset (NESARC) and a rich body of literature. The planned analysis will produce significant and actionable results.