larkral

[larkral]

eternal debotion

but what if i read one of your fanfics and then went to your ao3 accounts and read all of your fanfics and left a comment on every single chapter of every single one and you got spam emails from all of my kudos and comments and it made you smile, what then? what if i brighten your day with my words like you did mine, what then???

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when i say “that reminds me” & theres zero connection you just have to take my word for it theres no time to explain

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Harvard University

launched a free college course online that covers basic U.S. Government, understanding the constitution and how to recognize a dictatorship takeover.

Here is the link to the free course "We the People: Civic Engagement in a Constitutional Democracy"

https://pll.harvard.edu/course/we-people-civic-engagement-constitutional-democracy.

We understand that the current catalog of FREE COURSES at Harvard is being EXTENSIVELY EXPANDED, so you'll want to check their website from time to time to see which new courses are being added.

Government Courses | Harvard University

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Part 17 in my weekly poster series of 2025

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Yey finally I joined to the Artist’s starter pack trend ⭐️

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My bind of @facewithoutheart's fic This Will All Go Down In Flames

❤️‍🔥

This was my first time binding a fic and many mistakes were made but I'm really happy with how it turned out!

Some details:

I listened to @facewithoutheart's playlist for this fic almost the entire time I worked on this (and I watched 9-1-1 which was also @facewithoutheart's influence)

Cover created in Procreate using the studio pen

Font used for author's name on cover is Pilot Light

Book cloth made of out Heat n Bond, tissue paper, and Essex Cotton/Linen blend black fabric

Title design on front cover and stars on back cover made using Cricut holographic heat transfer vinyl in red

Flames on front cover and text on back cover made using Cricut iron on foil in red, spine in gold

Headband made out of excess Cricut holographic vinyl ironed onto excess fabric

End papers made out of 65lb black card stock and Cricut gold foil, font is Viktorie

Chapter title font: PF Fuel in Decay

Paragraph font: Minion Pro in Book

Twitter font: Roboto

Text message font: DINOsaur in Book

News article font: Times New Roman

Paper used was Hammermill 20lb paper in Cream

I used InDesign, InCopy, Illustrator, Photoshop (because I am a masochist)

The most EXTRA thing I did was the end papers. I wanted to use the same font I used on the back cover but based on the way the Cricut Design Space works, it wasn't as simple as just turning the font into an SVG so I hand traced each letter 🙃 (worth it)

You can check out my WIP posts here, here, and here.

Thank you everyone who weighed in each week and who helped me with formatting! Thanks for coming on this journey with me! ❤️‍🔥❤️‍🔥❤️‍🔥

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I know most people don't care about anything unless it has to do with the U.S. but can we please start talking about the Canadian election.

Please don't vote for Poilievre. He's basically the Canadian Trump and plans to put in place laws that harm trans youth, and lots of other shit.

Please vote istg this is the only way anything will get better. Poilievre has been kissing millionaires and billionaires asses. He'll make life even harder, and he loves Trump.

Reblogs are appreciated, especially if you aren't Canadian.

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If you see this you’re legally obligated to reblog and tag with the book you’re currently reading

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common spiny flower mantis, as an apology for the hiatus🌷

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"Two researchers in the US and Australia have discovered important mechanisms that prevent B cells from attacking the body’s own tissues in autoimmune diseases like arthritis, lupus, and multiple sclerosis—and in the process have won a prestigious prize.

Normally, the body’s immune system protects us from viruses, bacteria, and foreign substances. However, in autoimmune diseases, the immune system starts attacking tissues in the body instead.

Researchers had long tried to discover the cause of autoimmune diseases. But, Christopher Goodnow and David Nemazee, independently of each other, adopted a new approach.

They asked why we do not all develop these diseases. Their focus was on B cells which, together with white blood cells and T cells, are the building blocks of our complex immune system.

“They have given us a new and detailed understanding of the mechanisms that normally prevent faulty B cells from attacking tissues in the body, explaining why most of us are not affected by autoimmune diseases,” says Olle Kämpe, member of the Royal Swedish Academy of Sciences and chair of the Crafoord Prize committee that awarded the pair 6 million Swedish kronor ($600,000).

Neutralize B cells

In recent years, physicians have started to experiment by using existing drugs to neutralize B cells for patients with severe autoimmune diseases, including lupus, rheumatoid arthritis, and multiple sclerosis, which has proven to be very effective at improving their quality of life.

Thanks to this year’s Crafoord Prize Laureates, we have gained fundamental new knowledge about what is happening in the immune system during autoimmune disease attacks.

“This also paves the way for development of new forms of therapies that eventually can cure these diseases—or might prevent them in the future,” said one professor of clinical immunology at the Royal Swedish Academy of Sciences...

More details from the video, since the article glosses over the particulars:

"The laureates discovered what is now called B cell tolerance.

When B cells develop in the bone marrow, not all of them are perfect. To remove the faulty ones, a mechanism starts, in which defective cells are programmed to destroy themself through apoptosis.

The laureates discovered two new mechanisms that are used if some of the bad cells are left. Re-editing, where the immune system alters the combination of receptors, and anergy, that silences B cells with self-reactive receptors.

The laureates were able to demonstrate that these mechanisms sometimes fail. This means that faulty B cells can cause an attack on the body's own tissues – leading to autoimmune diseases.

Thanks to the laureate’s discoveries, doctors like Anders Bengtsson soon felt able to start treating patients with lupus, arthritis, multiple sclerosis, and many other autoimmune diseases, with medicines that eradicated B cells.

Anders Bengtsson: "I'm very happy that B cells has gotten so much attention because of the laureates. I have seen my patients getting so much better and getting a better life."

Autoimmune patient: "Today, I feel very good. I really have hope in the research that it will revolutionise things and perhaps even cure it all. That’s what I want, hope for, and believe in.""

-Article via Good News Network, April 6, 2025. Video via The Royal Swedish Academy of Sciences, January 29, 2025.

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Please call this recession the Trump Slump.

We need to put Trump's name on this.

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Updated version of Boy Who Cried Wolf but there are actual wolves every single time and no one ever believes the boy - they get closer and closer every time he tries to warn them, until it's too late and the whole town screams at the boy for not warning them "enough", and blame him for the wolves at their door.

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I want a story about a king whose son is prophesied to kill him so the king is like “whatever what am I supposed to do, kill my own kid wtf is wrong with you” so he just raises him as normal, doesn’t even tell him about the prophecy, and instead of some convoluted twist of events that leads to the king’s murder the son grows up and when the king is very old and dying and in excruciating pain the kid is just like alright I'mma put him out of his misery.