notebooks-and-coffeecups

[notebooks-and-coffeecups]

do it scared

[notebooks-and-coffeecups]

i've been mixing flesh, wax, chemicals and dyes for months to obtain these images

[notebooks-and-coffeecups]

[notebooks-and-coffeecups]

💗📑STUDY LIKE YOUR FAVORITE CHARACTER💗📃

Source : Pinterest

[notebooks-and-coffeecups]

cozy studies

[notebooks-and-coffeecups]

I saw a TikTok recently that really changed my view on education and learning. I forget the exact quote but it said something along the lines of “learn in good faith, and the grades will come”

So often I find myself obsessing over getting an A and not taking time to enjoy the fact that I am studying what middle school/high school me dreamed of. My younger self would hear about the things I am accomplishing and would be so excited. So that raises the question, if I picked these classes, why should my desire for a 4.0 outweigh letting myself enjoy the learning process and just doing the best I can? Good grades come to those who like and resonate with the material being taught. Maybe instead of focusing on memorization for some topics, emphasizing and spending time on relating the content and deepening my understanding is better. I've found that my chem lecture is so fascinating and just having the opportunity to learn more about the complexity of the world around us is so cool. While reaction rates can be boring, when thinking about it, catalysts have huge biological impacts in our body's daily functioning. Life simply would not be able to do what it does without these reactions. I am learning about details that relate to the reactions that allow me to have the energy to move. Learning becomes more valuable when you don't focus on the destination( a grade) but think about it as a journey.

[notebooks-and-coffeecups]

Day 12/13

I’m combining yesterday and today because exam revisions consumed my life and I’m just now finding a moment to take a breath and post. I spent my day writing a lab report about aspirin synthesis for my lab tomorrow. The lab part itself was actually really cool and I learned a lot, but the 10 page lab report was definitely a bit excessive for a summer course that is condensed into 5 weeks. I’m slowly getting a grove and figuring out my professors exam vibe so I’m hoping my exam score will reflect how hard I’ve been working. For whatever reason I’m struggling to pick up content but I’m hoping that my hard work pays off.

[notebooks-and-coffeecups]

I start my diy post-bacc this fall and I’m so excited to be back in school! I took two years off to deal with some health issues but I’m so ready to start working towards med school again!

[notebooks-and-coffeecups]

As a very chronically ill non-trad student, ask me questions!

SPOONIE QUESTIONNAIRE

[notebooks-and-coffeecups]

Back in the 1960s, the U.S. started vaccinating kids for measles. As expected, children stopped getting measles.

But something else happened.

Childhood deaths from all infectious diseases plummeted. Even deaths from diseases like pneumonia and diarrhea were cut by half.

“So it’s really been a mystery — why do children stop dying at such high rates from all these different infections following introduction of the measles vaccine,” says Michael Mina, a postdoc in biology at Princeton University and a medical student at Emory University.

Scientists Crack A 50-Year-Old Mystery About The Measles Vaccine Photo credit: Photofusion/UIG via Getty Images

[notebooks-and-coffeecups]

balls

[notebooks-and-coffeecups]

GABA

γ-Aminobutyric acid (GABA) is the principal inhibitory neurotransmitter known to counterbalance the action of excitatory glutamate, and is responsible for at least 40% of inhibitory synaptic processing throughout the central nervous system (CNS) (Bowery and Smart, 2006). 

Binds to transmembrane receptors 

Initiates the opening of ion channels

allowing either Cl- ions to flow into the��cell, or K+ ions to flow out. 

This results in a negative change in the transmembrane potential, and usually consequent hyperpolarization. Hyperpolarization increases the threshold which must be reached before firing, in turn reducing the probability of action potential initiation, and causing neuronal inhibition.

Due to the wide distribution and utilization of GABA, early GABAergic drugs had very generalized effects on CNS function. More recently, at least two distinct classes of GABA receptor, GABAA and GABAB, have been identified (Olsen and DeLorey, 1999). 

GABAB receptors 

G protein-coupled

indirectly link to K+ channels

can decrease Ca2+ conductance and inhibit cAMP production 

via intracellular mechanisms linked to their G protein. 

The GABAA receptor

exists as part of a larger, ligand gated macromolecular complex 

with five major binding domains for a variety of neurotransmitters.

GABA also has roles outside of the CNS, which made it difficult initially to define as a neurotransmitter. It is secreted in pancreatic β-cells, where it binds to GABA receptors on the neighbouring islet α-cells. This inhibits them from secreting glucagon, which would counteract the effect of the insulin produced by the β-cells (Rorsman et al., 1989). GABA has also been detected in many peripheral tissues, and immune cells can express receptors for GABA.

[notebooks-and-coffeecups]

Cool science post!!! Please enjoy! And keep in mind just because something has a higher LD50 (more needed to kill you, less toxic) doesnt mean it's magically Better. Aspirin has a lower LD50 than hydrochloric acid, vitamin D has a lower LD50 than cocaine, and nicotine has a lower LD50 than heroin. Also, this chart doesn't take into account chronic health effects or sub-lethal toxicity. Just how much is needed to kill you in one dose.

A few things that stood out to me (assuming a statistically average, 70kg adult):

>MSG is 5 times less toxic than table salt, per gram (it has 5 times less sodium per gram). And it tastes better, too! The long term health effects (other than specific allergies, which are immediate) are minimal, its a misconception that it's extremely unhealthy.

>Botox will kill at 0.000000002 grams. And we inject it into our faces to look younger. What the heck, guys.

>LSD is dosed in increments of 100μg, or at about 11,000x BELOW its acute toxic dose. This is known as a "therapeutic window", how far is the useful dose from the toxic dose. LSD has a fantastic therapeutic window compared to many medicines, but its still so small (similar EFFECTIVE dose to fentanyl, 5000% higher LD50) that extreme caution must be taken in dosing. A toxic but nonlethal dose of LSD is gonna leave some bad psychological damage.

>you can eat twice as much Magic Eraser as you can table salt before dying. I have no idea what to do with this information, but there you go.

>you'll die if you drink 10% of your body weight in water. This is pretty hard to do, but there are vanishingly rare cases where people drink so much water that their blood cells explode.

>CBD technically has a lower LD50 than THC? Both are pretty non-toxic, it'd take 70 GRAMS of CBD at once to kill you, and it's usually dosed in MILLIgrams. However, a quarter of the LD50 of THC would be a very very bad time (ever had too many edibles?) while a quarter of the LD50 of CBD would likely just feel drunken.

[notebooks-and-coffeecups]

Productivity (Day 4/10)

October 30th, 2018

I was able to work on Microbiology Lecture notes, and supplemented them with Osmosis Med videos. Found this local coffee shop and I could really embrace the fall vibes here 🍂☕️

[notebooks-and-coffeecups]

Almost done planning my first LSAT tutorial video. The lesson will cover question types, and routing the questions for max speed. Stay tuned!

[notebooks-and-coffeecups]

[ 25.02.19 ] “have some fire. be unstoppable. be a force of nature.”

[notebooks-and-coffeecups]

Innate and Adaptive Immunity

There are 2 systems of immunity - innate immunity and adaptive immunity. Thank you @coffeeloveinglazyfox, for the suggestion!

Keep reading