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Florence Nightingale, first practicing nurse epidemiologist. Developed the first organized program for training nurses, the Nightingale Training School for Nurses (St. Thomas' Hospital, London). Established the first health-maintenance-and-restoration-based nursing philosophy. Known as the "lady with the lamp" during the Crimean War (1853) where she volunteered, traveling the battlefield hospitals nightly to treat the wounded.

Clara Barton, founder of the American Red Cross (1881). She risked her life provided self-taught nursing aid to wounded soldiers on the battlefields during The Civil War (1860-1965), and became referred to as the "Angel of the Battlefield". One of the first women to work for the federal government, she made the Office of Missing Soldiers to aid in the reunion of more than 20,000 soldiers with their families. While providing aid during the Franco-Prussian War (1869), the Red Cross movement was first brought to her attention, inspiring her to bring the movement to America.

Dorothea Lynde Dix, an advocate of indigenous people and the mentally ill. She visited multiple mental institution, reporting her findings and advocated for better managed institutions, eventually establishing asylums of her own. During The Civil War (1860-1865), she aided the Union army by recruiting more than 3,000 nurses and was designated as the Superintendent of Army Nurses. She was known and respected for providing aid to the wounded soldiers from both Confederate and Union sides.

Mary Ann Ball, aka Mother Bickerdyke. She was a hospital administrator for the Union soldiers during The Civil War (1860-1865), regulating supplies and provision for the troops. Referred to as one of the best "generals" during the war for her efforts and organizations of military hospitals, following the war she remained an advocate for veterans - becoming an attorney for those who faced legal issues. 300 hospitals were built to aid the wounded over 19 different battlefields from her involvement.

Harriet Tubman, provided safe passage for slaves during the Underground Railroad movement. Known as the "Moses" of her people, her actions resulted in more than 300 slaves being lead to freedom. She provided nursing aide to the Union forces during The Civil War (1862-1865). Following the war, she played in active role in causes including the Womens Suffrage, and created the "Harriet Tubman Home for Indigent Aged Negroes" where orphans and the elderly could be taken in and care for.

Mary Mahoney, brought awareness to the cultural and racial diversity in nursing, emphasizing respect and the inclusion of all in the profession. The first African-American to receive an official education for the nursing profession (New England Hospital for Women and Children, Boston - 1874). She became the first African-American member of what is now referred to as the American Nurses Association, and helped start up the National Association for Colored Graduate Nurses in 1908.

Isabel Hampton Robb, a large influence in the advancement of the nursing social status in society. She influenced the system of nursing education by implementing a grading policy in the program to improve the quality of the students graduating from the program. She authored the comprehensive and foundational text, Nursing: Its Principles and Practice (1893), and helped to standardize the nursing education all around. She served as president of both the National League for Nursing Education and what is now referred to as the American Nurses Association.

Lillian Wald, opened the Henry Street Settlement (1893) with her fellow nurse graduate, Mary Maud Brewster. Addressed the health needs of poor immigrant families residing in tenements of New York City's Lower East Side. Coined the term "public health nurse", she fought for public health care, women's rights, and children's rights. Her and Mary Brewster started the Visiting Nursing Service of New York. During her work at the Henry Street Settlement, she established one of the earlier playgrounds and aided in paying salary to the first Public School Nurses in NYC. She had a hand in starting up the United States Children's Bureau, the National Child Labor Committee, and the National Women's Trade Union League.

Mary Adelaide Nuting, known for becoming the first nursing professor in 1906 (Columbia Teachers College), and assisted in getting nursing education in Universities across the states. She attended the first nursing training following Florence Nightingale's inflence (John Hopkins Hospital Training School - 1889). Throughout her advancement in the nursing profession working at the school, she assisted in advancing the program - brought in scholarships and on-the-field experience; her work influencing other Universities create and better their own nursing programs. Founder of the American Journal of Nursing (1900), she also became the first registered nurse in the state of Maryland. Several of her authored and coauthored books are still implemented today in nursing programs throughout the nation.

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