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Vitreous Tamponades Market Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2018 – 2026
Vitreous tamponades are essentials used in vitrectomy procedures for healing or reattachment of retina and in vitreous dysfunction. They are majorly used in various retinal disorders such as retinal detachment, diabetic retinopathy, retinitis pigmentosa, retinal degeneration, vascular occlusion, macular hole, epiretinal membrane, macular edema, uveitis, and retinopathy of prematurity. Vitreous humor is clear and colorless fluid made up of 99% water. It occupies the space between retina and lens of the eye. Vitreous protects the eye by holding their spherical shape and helps to stay retina in place. In vitreous dysfunction, vitreous gets liquefied and shrinks in size, which eventually leads to visual impairment. As vitreous humor cannot regenerate, the cavity must be filled with substitutes by vitrectomy surgery to treat vitreous dysfunction. They are replaced with artificial substitutes, which closely resembles the native vitreous in both function and structure. The ideal vitreous substitutes should be transparent, biocompatible and elastic. Vitreous substitutes such as Semi fluorinated alkanes tamponades and silicone oil/semi fluorinated alkanes combinations are more superior physically and chemically than conventional gas or liquid tamponades. Natural polymers, hydrogel, transplant/implants, and vitreous regeneration are new vitreous substitutes in developmental stage.
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Vitreous substitutes are used as intraoperative and postoperative tool for surgical treatment of vitreoretinal disease. They are used as temporary fillers, permanent fillers or used as surgical tool during short intraocular surgery.
According to the data published by National Center for Biotechnology Information (NCBI) in January 2014, retinal detachment is the most common vision-threatening retinal condition, with an incidence of 1 in 10,000 individual annually, which corresponds to around 8,000 new cases in Germany annually. Moreover, according to the study findings by Journal of Ophthalmology in 2016, the prevalence of retinal detachment ranges from 6.3 to 17.9 per 100,000 people annually. Increasing incidences of retinal detachment, ophthalmic conditions, and retinal disease are expected to drive the growth of vitreous tamponades market in near future. However, complications associated with the conventional vitreous substitutes hamper the vitreous tamponades market growth. The intraocular gases have high risk of elevating intracellular pressure on the surrounding retinal membrane. The widely used silicone oil shows short life cycle and needs to be removed early, due to the complications such as emulsification, band keratopathy, and secondary glaucoma. Heavy silicone oil leads to significant intraocular inflammatory reactions and may cause severe complications than conventional silicone oil. Although polymer appears to be more biocompatible, they biodegrade quickly. Hence, long term biocompatibility of existing vitreous substitute material and need to develop more suitable materials is expected to replace the existing vitreous humor, in turn boosting the growth of vitreous tamponades market.
Vitreous tamponades market taxonomy:
By type:
Gaseous tamponades
Sulfur hexafluoride (SF6) gas tamponade
Perfluoropropane (C3F8) gas tamponade
Liquid tamponades
Silicone oil liquid tamponade
Perfluorocarbon liquid tamponade
Balanced salt solution
Quick filling hydrogel is expected to replace conventional vitreous tamponades in near future
According to the recent finding by the University of Tokyo in March 2017, new hydrogel-elastic gel was introduced in the vitreous tamponades market. The new hydrogel is administrated in liquid form behind the retina, which then turns into jellylike substance in just 10 minutes. The conventionally available vitreous substitute such as silicone oil and gas do not mix well with water, hence they are not suitable for long term application and require long period for gels formation, thereby making them impractical to use during the surgery. The hydrogels have high water content and composed of similar materials those found in soft tissue of eye. Conventional hydrogels absorb water and swell resulting into pressure on the surrounding retinal tissues, which eventually cause damage. The study carried out on hydrogel implanted rabbits showed no adverse effects even after 410 days of treatment.
The unique ability of newly developed hydrogel to transform into gel form in very short period and low polymer concentration makes it suitable for broader applications to treat trauma, tumors, and vitreoretinal disease. Potential development in vitreous substitutes are further expected to drive growth of the vitreous tamponades market in near future.
The major players operating in the global vitreous tamponades market includes Alcon, Inc., Carl Zeiss Meditec AG, Fluoron GmbH, D.O.R.C. Dutch Ophthalmic Research Center B.V., AL.CHI.MI.A.SRL, CROMA-PHARMA GmbH, and Valeant Pharmaceuticals International, Inc.
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Intravenous Solutions Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2026
Intravenous solutions are the chemically prepared fluids, which are administered in the body through venous circulation to maintain or replace the lost body fluid level. There are various types of IV solutions that have different effects on a human body. Majority of intravenous solutions constitute of solvent and solute out of which solvents are sterile water and solutes are electrolytes such as sodium, potassium, and chloride. Intravenous solutions market is expected to grow at high rate over the forecast period, owing to increasing diseases causing fluid loss, dehydration and malnutrition, increasing rates of chronic diseases, and surgeries.
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Increasing prevalence of Diarrhea is expected to boost the growth of intravenous solutions market in near future
According to World Health Organization (WHO) in 2017, diarrhea is the second largest cause of death around the globe. Around 1.7 billion people suffers for diarrhea every year and causes around 525,000 deaths. IV solutions are given to the patients suffering to maintain their body fluid level as diarrhea causes dehydration, malnutrition, and excess fluid loss from the body. Thus, increasing prevalence of diarrhea is expected to rise demand for IV solutions and fuel its market growth in near future. According to WHO in 2017, around 180,000 people suffer from burns yearly and between 20 and 50 million people suffers from severe injuries and blood loss due to road accidents. Burns, shocks and blood loss due to trauma or road accidents causes severe fluid loss from body, which can be retained by giving IV solution to patients. Increasing incidents of burns, shocks and excess fluid loss due to trauma and accidents are expected to boost the growth of IV solutions market in near future. Rising prevalence of chronic diseases and surgeries are also expected to fuel IV solution market as IV fluids are given to the patients suffering from chronic diseases for recovery after the surgery. However, the presence of domestic players which provide low quality products that does not provide optimum results are hampering the market growth.
Market Taxonomy
The intravenous solutions market is segmented on the basis of solution type, composition, and end user
On the basis of solution type, the intravenous solutions market is segment into:
Crystalloid solutions
Colloid solutions
Free H 2O solutions
Blood products
On the basis of composition, the intravenous solutions market is segment into:
Normal Saline (0.9% Normal Saline (0.9% NaCl)
Hypertonic saline (3, 5, & 7.5%)
Lactated Ringer’s
Dextran
D5W (5% dextrose in water)
Whole blood
Platelets
Others
On the basis of end user, the intravenous solutions market is segment into:
Hospitals
Clinics
Ambulatory surgery centers
Others
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Asia Pacific is expected to dominate IV solution market due to high ratio of diseases related to fluid loss
Regional market for the intravenous solutions market by Coherent Market Insights is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. Asia Pacific expected to hold the dominant position in market due to highest rate of diarrhea, chronic diseases, and increasing rate of surgeries. According to the United Nations International Children's Emergency Fund (UNICEF) in 2016, every two children out of four in Asia is suffering from diarrhea and malnutrition. Rate of diarrhea is very high in Bangladesh, China, and Pakistan. The rate of chronic diseases in Asia is high with increasing population in China in India. Africa is expected to be the second largest contributor to the IV solution market, owing to high ratio of diseases such as metabolic acidosis, hyponatremia, and fistula drainage due to poor sanitation and improper healthcare system. Prevalence of road accidents and trauma is very high in Africa that resulting excess loss of body fluid, which can be retained with IV solutions. According to WHO in 2015, Africa had highest prevalence of road accidents among all others regions.
Key players are collaborating with different organizations to increase the market penetration of products
Major players in global intravenous solutions market are B. Braun Melsungen AG, Baxter, Fresenius Kabi AG, Grifols, ICU Medical, Inc., Omnicare, JW Life Science, Hospira Inc, Sichuan Kelun Pharmaceutical, and Vifor Pharma. Key players are collaborating with different organizations and working with them to reduce malnutrition by supplying their product. In 2017, Baxter collaborated with American Society for Parenteral and Enteral Nutrition (ASPEN) an organization, which drives the science and practice of clinical nutrition to reduce the incidents of malnutrition in America.
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Laxatives Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2018 –2026
Pigmented lesion is a skin disease usually referred to as melanocytic proliferations. Pigmented lesions are brown, black or blue in color, due to melanin, blood, or exogenous pigment. Spreading or growing lesions, pigmented lesions on exposed skin can be a symptom of skin cancer. Pigmented lesion are classified as non-melanocytic lesions and melanocytic lesions, and further classified as benign and malignant. Malignant lesion is a tissue, which appears abnormal under microscopic examination, and is more likely be cancer tissue. Therefore, removal of premalignant lesion reduces proliferation and occurrence of malignant skin diseases. Early diagnosis and complete removal of lesions can prevent occurrence of all types of skin cancers. Factors for pigment lesion are natural and environmental that includes, photodamage i.e. constant exposure to ultraviolet (UV) radiation, which leads to skin problems, early skin aging.
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Almost all age group population are susceptible to pigment lesion. There are wide range of laser treatments available for pigmented lesion such as ErYAG, MedLite laser, which are effective and relatively affordable.
Increasing laser systems for treatment of pigmented lesion favors growth of the pigmented lesion treatment market
Manufacturers are focusing on innovation to deliver new and advanced treatment options for pigmented lesion. For instance, in 2014, Syneron Medical Ltd. launched PicoWay picosecond device at the 23rd European Academy of Dermatology and Venereology (EADV) Congress in Amsterdam for pigmented lesion treatment and tattoo removal. PicoWay is a dual wavelength device, with 532nm and 1064nm wavelength. Furthermore, in 2014, Lutronic Corporation launched Lutronic XT Q-Switched, frequency doubled Nd:YAG laser, known as the Spectra XT, the system includes several treatment application such as pigmented lesion, tattoo removal, melisma, pore-size reduction, and skin-rejuvenation.
Cutera, Inc. introduced two new laser systems at the 72nd American Academy of Dermatology conference, 2014 in the U.S. Both the lasers, named excel HR and Enlighten, are targeted for hair removal, tattoo removal, and benign pigmented lesion. In 2016, Cynosure received FDA clearance to market PicoSure Energy delivery system for tattoos and pigmented lesions.
Pigmented Lesion Treatment Market taxonomy
By Laser Type:
Fractional CO2
Diode
Infrared
Alexandrite
Nd:YAG
Pulsed
Potassium-Titanyl-Phosphate
By Indication Type:
Non-melanocytic lesions
Inflammatory
Hamartomas
Benign neoplasms
Malignant neoplasms
Melanocytic lesions
Benign
Malignant
By End User
Hospitals
Skin Clinics
Others
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Asia Pacific is expected to show significant growth in the pigmented lesion treatment market over the forecast period
On the basis of region, the global pigmented lesion treatment market can be segmented into North America, Europe, Asia Pacific, Latin America, Middle East, and Africa. North America is expected to account for the largest share, followed by Europe and Asia Pacific, respectively over the forecast period. Growth of the pigmented lesion treatment market in North America is driven by factors such as increasing aesthetic awareness and growing prevalence of pigmented lesion. According to Skin Cancer Foundation, yearly over 5.4 million cases of non-melanoma skin cancer are reported in the U.S. and over 3.3 million people receive treatment, which in turn favors growth of pigmented lesion treatment market in North America. Pigmented lesion treatment market in Asia Pacific is expected to witness high growth owing to factors such as increasing government support for treatment of lesion. For instance, the New South Wales (NSW) Government selected 12 innovative tech start-ups to exhibit at CeBIT Australia. Among these companies, Dermaspec, which is a high-quality, color calibrated low-cost camera for dermatoscopic imaging of pigmented skin lesions. at a modest cost, which in turn will favor the growth of pigmented lesion market in Asia Pacific region.
Furthermore, the growth of Asia Pacific is supported by the Syneron Medicals Ltd. revenue of 2016 as the North America product revenue of the Syneron was up approximately 20% Y-o-Y, Asia-Pacific product revenue was up approximately 25% Y-o-Y, and EMEA region product revenue was up approximately 9% Y-o-Y.
Increasing competition in the product space is driving innovation in treatment systems, which is expected to fuel growth of the global pigmented lesion treatment market
In September 2017, Fotona — a company based in the U.S. and Europe — received FDA clearance for its new StarWalker MaQX Q-Switched laser system for treating tattoos, pigmented and vascular lesions, acne and scar revision, and even for permanent hair reduction. Such constant product approval increases the competition between key market players in pigmented lesion treatment market.
Key players operating in the global market of pigmented lesion treatment market include Lutronic Corporation, Fotona d.d., Alma Lasers, Ltd., EL.En. S.p.A., Solta Medical Inc., Cynosure, Inc., Syneron Medical Ltd., Sciton, Inc., Cutera Inc., Lumenis Ltd., Strata Skin Sciences, Inc., and Lynton Lasers Ltd.
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Laxatives Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2018 –2026
Laxatives are chemical substances that are helpful in increasing stool motility and bowel movement, and are thus, used to treat and/or prevent constipation. Increasing incidences of medical disorders such as eating disorders where laxatives are overused and increasing incidences of constipation for which laxatives are primarily used for treatment may lead to increased consumption of laxatives, and hence, can result in laxatives market growth. Exceeding the prescribed dose of laxatives leads to various health complications such as chronic constipation, diarrhea, dehydration, and blood in the stool. In spite of this, laxative abuse is rather common. According to a study published in National Center for Biotechnology Information (NCBI) in 2010, people abusing laxatives can be categorized into four groups. The largest group constitutes individuals suffering from eating disorders such as anorexia or bulimia, and prevalence of abuse in this group ranges from 10% to 60%, according to the same study. The remaining three categories are - individuals who began using laxatives when constipated but didn’t after getting better; individuals who are involved in sports activities such as weight lifting, and surreptitious laxative abusers. .
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Increasing incidence of constipation is expected to drive laxatives market growth
Constipation is one of the most frequently diagnosed gastrointestinal disorders globally. However, incidence rates vary by region. According to a report published by Canadian Digestive Health Foundation in 2014, 1 out of 4 people living in Canada recorded to have symptoms of constipation in 2014. Chronic constipation rates for women were almost twice as high as for men in Canada.
Increasing incidence of constipation were also recorded in other developed economies such as the U.S. and UK. According to a report published by Coloplast—a global leading player in ostomy care, urology and continence care, and wound and skin care, 1 in 7 adults were affected by constipation during 2014 - 2015 in the UK. The condition was even worse for children, wherein 1 in 3 were affected by constipation during 2014-2015.
The scenario is similar in emerging economies such as India, Brazil, and China. According to Abbott Gut-Health Survey, around 14% of the urban population in India suffered from chronic constipation in 2015. As these people are living in urban area where access to healthcare services is rapidly improving, the number of diagnosed patient will increase which in turn will result in laxatives market expansion.
Increasing incidence of eating disorders and increasing availability of over-the-counter laxatives are expected to drive market growth
Developed economies such as the U.S, UK, Australia, and Germany have witnessed continuous rise in incidence of eating disorders. A report commissioned by Beat in 2015, estimated that over 725,000 people were affected by the disease in UK. According to South Carolina Department of Mental Health (DMH) around 8 million people, including seven million women and one million men in the U.S. were recorded suffering from an eating disorder, in 2015. .
Patients suffering from eating disorders are more likely to overuse laxatives. Also, laxatives as over-the-counter (OTC) drugs, have influenced in the excessive overuse. This overuse of laxatives has significantly contributed to growth of the laxatives market.
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Negligence and/or unwillingness among patients to talk to doctor about constipation has limited the growth of laxatives market
Majority of the people suffering from constipation are embarrassed to consult their general practitioner (GP) regarding constipation, even in developed economies such as the UK. According to the study released by Coloplast in 2015, around 1 in 5 (i.e. 20%) people in UK, reportedly felt embarrassed to talk to their GP about constipation. This has resulted in underreporting of the people suffering from this condition.
Majority of the population, especially in rural areas of emerging economies such as India, do not feel the need to consult a doctor for constipation. This negligence is due to lack of literacy, low accessibility to healthcare facilities, low per capita income, and higher self-medication practices in such regions. This has proven to be detrimental to growth of the laxatives market, as people who really require laxatives for treatment are not actually taking it.
Key companies operating in the global laxatives market include AstraZeneca plc, Boehringer Ingelheim GmbH, Bayer AG, GlaxoSmithKline plc, Abbott Laboratories, Takeda Pharmaceutical Company Ltd, Teva Pharmaceutical Industries Ltd., Mylan N.V., and Purdue Pharma L.P.
Global Laxatives Market Taxonomy:
By Drug Type:
Bulk-forming Agents
Emollients (Stool Softeners)
Lubricating Agents
Stimulating Agents
Hyperosmotic Agents
Saline Laxative Agents
Chloride Channel Activators
Others
By Availability:
Over-the-counter (OTC)
Prescription
By Drug Type:
Generic
Branded
By Route of Administration:
Oral
Rectal
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Also, Coherent Market Insights has a proprietary database of pipeline biologics and biosimilars, called PHASE-XS. This database provides analytical data in addition to the clinical information of ongoing trials for biologics and biosimilars. An amalgamation of more than 30 parameters, PHASE-XS helps biotechnology and pharmaceutical companies to analyze the market trend, competition, and market potential. For more information or to access this database, kindly click on the below link or contact at [email protected]
https://www.coherentmarketinsights.com/phase-xs/
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Laboratory Filtration in Health Care Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2018 – 2026
Filtration has a wide laboratory-scale applications as it is used in various fields, such as research laboratories, microbial analysis, discovery and development of drugs and vaccines, and virus removal. Laboratory filtration is used in sample preparation prior to the analysis by using an instrumental analytical method such HPLC/UHPLC. Laboratory filtration is also used in instrument protection. For instance, hydrophobic filter in the pipette. Furthermore, analytical filtration are used in water quality testing to determine the microbial content of samples. Considering the wide application for laboratory filtration products, increase in the usage of analytical instruments, and introduction of advance filters is expected to drive the growth of laboratory filtration in healthcare market during the forecast period.
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Technological advancement is expected to boost the growth of the laboratory filtration in healthcare market
The laboratory filtration market has witnessed new product launches and innovative technologies. The technological advanced product provides high reliability and throughput as compared to conventional methods. For instance, Merck KGaA Durapore 0.22 µm hydrophilic Polyvinylidene fluoride (PVDF) membranes is used in endotoxins removal and is designed for sterile filtration. Durapore also provides high protein recovery with minimal loss of valuable product. Durapore is also used for filtration of lipids in small and large volume system. Reverse Osmosis systems is an another technique that provides various benefits and widely used in laboratories as it is a physical process, which does not uses regenerating chemicals and hence, provides excellent defense against viruses, pyrogens, and bacteria making reverse osmosis systems cost-effective technique. Technological advancements in filtration products have resulted in an increase in the adoption rate, which in turn is expected to result in growth of the laboratory filtration in healthcare market.
Increasing focus towards the development of biopharmaceutical molecules and the rising application of filtration techniques are expected to contribute for the growth of the laboratory filtration in healthcare market
Companies are developing advance products for the treatment of various diseases and to develop this molecules wide range of laboratory filters are used in clinical and research institutes, which are expected to increase the demand for laboratory filtration. For instance, Ultrafiltration (UF) are widely used for the removal of suspended solids like bacteria, high-molecular-weight molecules, and endotoxin. The robust ultrafiltration processes plays crucial role in the development of bio-pharmaceutical products. Cellulose nitrate membrane filters are prepared by the reaction of nitric acid and cellulose. This filters are widely used for the filtration of peptides and proteins in molecular biology. Thus, increasing use of filtration technique in research and development of molecules is expected to support the growth of the laboratory filtration in healthcare market.
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The key players operating in the global laboratory filtration in healthcare market include Merck Millipore, 3M Purification, Inc., Thermo Fisher Scientific, Inc., Sigma-Aldrich, Pall Corporation, Cantel Medical Corp, Sartorius Group, Macherey-Nagel Gmbh & Co., and GE Healthcare.
Global Laboratory Filtration in Healthcare Market Taxonomy –
The global laboratory filtration in healthcare market is segmented on the basis of product, technology, and end user
By Product–
Filtration Assemblies
Microfiltration Assemblies,Reverse Osmosis Assemblies,Ultrafiltration Assemblies,Vacuum Filtration Assemblies,Others
Filtration Media
Filter Papers ,Cellulose Filter Papers,Glass Microfiber Filter Papers,Quartz Filter Papers,Membrane Filters,Syringe Filters,Syringeless Filters,Capsule Filters,Filtration Microplates,Others
Filtration Accessories
Filter Holders,Filter Funnels,Filter Dispensers,Filter Flasks,Filter Housings,Cartridges,Vacuum Pumps,Seals,Other Accessories
By Technology–
Microfiltration,Ultrafiltration,Reverse Osmosis,Vacuum Filtration,Nano filtration
By End User –
Pharmaceutical & Biopharmaceutical Companies,Academic & Research Institutes,Hospital & Diagnostic Laboratories
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ECG Cable and ECG Lead Wires Market – Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2018–2026
Electrocardiograph machines are used to measure the electrical activity of a patient’s heart. The electrical activity of the heart is recorded with the help of 12-lead ECGs and 10 electrodes placed on patient’s limbs and surface of the chest. Furthermore, ECG applies to monitor the patient’s emergency situation to obtain quick results of heart’s size, position of heart chambers, the rate of the heart, rhythm, and any damage to heart muscles and effect of cardiac drugs.
According to the World Health Organization (WHO), cardiovascular diseases (CVD) is a number one leading cause of morbidity and mortality worldwide. The data represents high prevalence and incidence of CVD worldwide, which may need advance preventive measures and treatment. Thus, this factor may favor the growth of ECG cable and ECG lead wires market during the forecast period.
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Increasing high prevalence and incidence of cardiovascular associated diseases expects fuel the growth of ECG Cable and ECG Lead Wires Market
According to the World Health Organization (WHO), approximately 17.7 million people died due to CVD in 2015. Moreover, according to the Centers for Disease Control and Prevention (CDC), around 630,000 people in the U.S. die due to heart diseases every year and approximately 366,000 people died due to coronary heart disease (CHD) in 2015.
According to the British Heart Foundation (BHF), in 2014, cardiovascular disease (CVD) is the second leading cause of death in the UK. As per BHF, approximately 69,000 people died due to coronary heart disease (CHD) in 2014. Furthermore, according to European Heart Network, 2017, every year around 3.9 million deaths occur owing to CVD in Europe and approximately 1.8 million deaths in the European Union (EU).
Besides, according to Population Reference Bureau (PRB), in 2016, around 46 million people are aged 65 years and older in the U.S. and it is predicted that, by 2060 this population will be 98 million. High prevalence and incidence of CVD and rising geriatric population is a major driving factor that may boost the growth of ECG Cable and ECG Lead Wires Market.
Revolution of wires to wireless technology in ECG monitoring system may reshape the healthcare delivery in near future
Emerging IoT healthcare technology is transforming the healthcare monitoring system, to reduce the health risks and ensure optimal patient care. In present scenario, wireless monitoring system took over ECG cables and lead wires. For instance, by removing ECG associated multitude wires, Peerbridge Health improved ECG monitoring efficiency by making of wireless electrocardiogram monitor – Peerbridge Cor which was patented in 2012 and cleared by the Food and Drug Administration (FDA) in October 2017. Cor devices have smallest on-body footprint for any wearable monitor which provides wireless multi-channels of ECG by water resistant electrodes for continuous remote monitoring of patient. Such products will transform the demand for ECG cable and lead wires significantly during the forecast period.
Global Key Players:
The major key players in the global ECG cable and ECG lead wires market include, Curbell Medical Products, Inc., 3M Company, Medtronic plc, Becton, Mindray Medical International Limited, Dickinson and Company, Koninklijke Philips N.V. and Welch Allyn, Inc
Global ECG Cable and ECG Lead Wires Market Taxonomy
On the basis of materials, product type, usability and application, the global ECG cable and ECG lead Wires market is segmented into:
By Materials
TPU (Thermoplastic Polyurethane)
TPE (Thermoplastic Elastomer)
Others (Silicone, PVC)
By Product Type
Single-Lead ECG Lead Wire
3-Lead ECG Lead Wire
5-Lead ECG Lead Wire
6-Lead ECG Lead Wire
12- Lead ECG Lead Wire
Others
By Usability
Reusable
Disposable
By End User
Hospitals
Clinics
Ambulatory Services
Home-Care
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Antidiabetic Biosimilars Market by Product, End-user and Geography - Trends and Analysis till 2024
Antidiabetic biosimilars market overview
Antidiabetics help control blood glucose levels in diabetic patients. Various types of antidiabetics include biguanides, thiazolidinediones, DPP-IV inhibitors, α-glucosidase Inhibitors, sulfonylureas, insulin, and GLP-1 receptor agonists such as exenatide. A biosimilar product is biological product that is approved on the basis that it is highly similar to a FDA approved biological product known as a reference product. Biosimilar manufacturers need to generate data from lab testing and clinical testing to demonstrate that the biosimilar developed provides the same therapeutic benefit to patients as the reference product.
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Patent expiries to drive growth of the global antidiabetic biosimilars market
The global antidiabetic biosimilars market is driven by increasing number of diabetes mellitus patients. According to World Health Organization (WHO) the number of people suffering from diabetes stood at 422 million in 2014. The global prevalence of diabetes among adults above 18 years increased to 8.5% in 2014 from 4.7% in 1980. Increasing incidence of lifestyle disorders such as obesity, increases the risk of diabetes and in turn drives growth of the antidiabetic biosimilars market. In June 2014, the European Medicines Agency authorized the first biosimilar of insulin Glargine, Abasaglar from Eli Lilly and Company and Boehringer Ingelhim International Gmbh, for treatment of diabetes mellitus. The biosimilar received U.S. FDA approval in 2016, which would fuel growth of the antidiabetic biosimilars market.
Furthermore patent expiry of insulin aspart and insulin lispro is projected to propel growth of antidiabetic biosimilars market. Biosimilar insulin have potential to reduce diabetes treatment costs, increase accessibility of insulin treatment and expand the number of insulin brands.
Constraints for growth of the antidiabetic biosimilars market
Biosimilars would have to face stringent regulatory requirements that would focus on their production before entering into major markets such as the U.S. While biosimilars have marked successful entry in the European markets, entry in the U.S. market is still a challenge due to stringent regulatory norms. Furthermore, biosimilars would need to gain favorable reimbursement to gain market traction.
Increasing number of diabetes patients driving the antidiabetic biosimilars market globally
Increasing incidence of diabetes, complexities in alternative diabetic therapies, and government incentives for introduction of low cost therapies are collectively creating a conducive environment for growth of the market. According to the International Diabetes Federation (IDF), there were around 59.8 million diabetic patients in Europe in 2015. The market for antidiabetic biosimilar is expected to be high in near future in Asia Pacific due to increase in research activities related to antidiabetic products and supportive government funding. North America region is projected to represent a lucrative market for antidiabetic biosimilar in the near future, as prevalence of diabetes is increasing in this region. According to the International Diabetes Federation, in 2015, over 29.1 million people in the U.S. suffered from diabetes.
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Tooth Regeneration Market - Insights, Opportunity Analysis, and Industry Forecast till 2024
Tooth regeneration market has been abuzz for a while with various new developments reported, commercialization of which is expected to transform whole dental industry. Though the development in tooth regeneration has been on upward growth trajectory since 1980s, it gained momentum post-2013. Many research institutes are focusing on conducting studies to understand the feasibility of tooth regeneration. While Asia Pacific is expected to dominate the addressable market, North America and Europe are expected to witness early launch of tooth regeneration products in near future. Asia Pacific market is expected to expand at the fastest CAGR, followed by Latin America and Middle East, respectively over the forecast period (2016-2024).
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Market Dynamics
With changing dental industry landscape, companies are emphasizing on product innovation in order to sustain and expand their business reach worldwide. Tooth regeneration is one such disruptive technology wherein early entrants are expected to capture major share of the dental market. Moreover, commercialization of tooth regeneration will lead to slowdown in the dental implant and equipment landscape. As such, tooth regeneration industry will dominate the whole dental market. Though the tooth regeneration holds immense potential to generate high ROI and at same time benefit society, high R&D cost and stringent regulations are key challenges being faced by the industry players. Tooth regeneration is expected to be commercialized on large scale post-2024.
Geriatric population demographics has emerged as the highest revenue contributor among population demography segment
Geriatric segment is expected to dominate the dental implants market throughout the forecast period. The segment accounted for 66.8% of global industry revenue in 2015. According to NIH, geriatric population have average 18.9 remaining teeth. Around 23% of geriatric population have no teeth, creating favorable market scenario for industry players. Over 18 million dental procedures are expected to be carried out among geriatric population between 2017 and 2024. Commercialization of tooth regeneration is expected to create lucrative market opportunity for industry players. North America and Europe are expected to collectively account for major share of global procedures by 2024.
Asia Pacific is expected to dominate the tooth regeneration market revenue post 2020
Tooth regeneration addressable market is expected to be highest in Asia Pacific, with China and India positioned as the major growth engines. Emergence of tooth regeneration is expected to capture this market. Also, the number of dental procedures is expected to grow at the highest CAGR of 9.7% in Asia Pacific between 2016 and 2024.
North America and Europe are expected to lose position to Asia Pacific by 2020. It is primarily attributed to increasing healthcare spending coupled with significant geriatrics population presence in Asia Pacific.
Tooth regeneration market players need to invest in R&D to harness stem cell technology to develop and commercialize tooth regeneration technology
Tooth regeneration market players are focused towards research and development to commercialize the target industry. Companies such as Straumann and DENTSPLY are working closely with some of the leading universities to understand the project feasibility. In 2015, researchers at University of Southern California (U.S) created gel to regrow enamel. Moreover, nanoparticles is also gaining momentum to boost dental tissue engineering. Various institutes such as Nova Southeastern University, Tufts School of Dental Medicine, University of Southern California, Wyss Institute at Harvard University, University of Nottingham, Institute National de la Sante et de la Recherche Medicale (France), etc are engaged in tooth regeneration technology. Various products are in the pipeline, commercialization of which is expected to happen post-2024. Most of these companies are focused towards enamel regeneration. Unilever UK developed ‘Regenerate Enamel Science’. The company holds 5 international patents for its NR-5 technology. The brand claims to regenerate 82% of the eroded enamel within 3 days. Many products are expected to emerge in near future creating exponential market opportunity for industry players.
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Market Taxonomy
This report segments the tooth regeneration market on the basis of application and population demographics. On the basis of application, the market is segmented into enamel, dentin and pulp. On the basis of population demographics, the tooth regeneration market is segmented as geriatric, middle aged, adults and others.
Detailed Segmentation:
Global Tooth Regeneration Market, By Application:
Enamel
Dentin
Pulp
Global Tooth Regeneration Market, By Population Demographics:
Geriatrics
Middle Aged
Adult
Others
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Antibiotics and Corticosteroids Market — Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2018–2026
Antibiotics are used to terminate the bacterial growth or bacteria itself in the case of bacterial infection, whereas, corticosteroids are used to treat the allergy and inflammatory condition. There are some functions which corticosteroids can perform while antibiotics cannot perform and vice-versa. At times, the physician prescribes the dose of antibiotics in addition with corticosteroids so that antibiotic will help attack the microorganism cell wall whereas the inflammatory process can be tackled by the corticosteroids. Corticosteroids also decreases the pain related to inflammation by inhibiting chemical mediators. Over dosage or misuse of both compounds might lead to adverse effects such as failure of immune system.
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Efficacy of combine treatment of antibiotics and corticosteroids on several chronic diseases is the major factor for growth of antibiotics and corticosteroids market
The use of antibiotics with the combination of corticosteroids has proven effective in the treatment of human respiratory syncytial virus (hRSV) infection, Cepacia syndrome, S. Aureus arthritis, pneumonia, Zika Virus, and Ebola. According to the data published in Journal of Tropical Diseases and Public Health, in 2016, around 6.3 million children died in 2013, wherein 51.8% died due to infectious diseases and largest was accounted due to pneumonia for around 935,000 deaths. However, around 3.4 million children are infected with the human Respiratory syncytial virus (RSV) which is associated to acute lower respiratory infections (ALRI). Supportive government activities in the favor of antibiotics and corticosteroids production is helping to boost the antibiotic and corticosteroids market. For instance, introduction of Antibiotics Incentives Now (GAIN) act which has the provisions to facilitate the development of therapy against antigen resistant pathogens is expected to propel the approval for antibiotics.
However, some of the restraints which are likely to hamper the growth of antibiotics and corticosteroids market include the adverse effect on high intake or misuse of both antibiotics and corticosteroids, use in animals which are later consumed by humans, and regulations and policies on use of antibiotics and corticosteroids.
Rising cases of infectious diseases and established healthcare sector is fuelling to the growth of antibiotics and corticosteroids market in North America
Regional segmentation of antibiotics and corticosteroids market by Coherent Market Insights comprises of North America, Latin America, Europe, Asia Pacific, the Middle East and Africa. North America hold the major share in the antibiotics and corticosteroids market due to the high prevalence rate of respiratory syncytial virus (RSV) infection and the need of antibiotic and corticosteroids treatment of such diseases. For instance, the data given by Centers for Disease Control and Prevention (CDC), around 2.1 million children are diagnosed with RSV and 14, 000 adult population die due to this disease annually. Latin America also hold the large share in the antibiotics and corticosteroids market followed by Asia Pacific due to the progress in pharmaceutical industry.
Industry players are involved in the regional expansion and collaborations with other companies to hold the larger share in the antibiotics and corticosteroids market
Key industry players operating the global antibiotics and corticosteroids market include Novartis, Pfizer, GlaxoSmithKline (GSK), Abbott Laboratories, Sanofi, Johnson & Johnson, Merck, Sumitomo, AstraZeneca, Cipla, and Astellas Pharma. The generic drug manufacturers are dominating in the antibiotics and corticosteroid market due to the presence of key drugs that are helping to generate the revenue with availability of few patent products. Adoption of various strategies such as regional expansion, novel product development, collaborations, and partnerships by the industry players to hold the major share in the antibiotics and corticosteroids market. For instance, Pfizer made an agreement with AstraZeneca in 2016, which has helped to acquire the commercialization and development right to the Pfizer’s business mostly outside the U.S.
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Rise in population with pneumonia is contributing to the growth of this disease segment in antibiotics and corticosteroids market
The global antibiotics and corticosteroids market is segmented by application, by antibiotics type, by end user, by disease type, and by region
On the basis of application, the antibiotics and corticosteroids market is segmented into
Humans
Veterinary
On the basis of antibiotic type, the antibiotics and corticosteroids market is segmented into
Macrolides
Tetracycline
Beta-lactams
Lincosamides
Glycopeptides
Aminoglycosides
Sulfonamides
Others
On the basis of end user, the antibiotics and corticosteroids market is segmented into
Hospitals
Medical clinics
On the basis of disease type, the antibiotics and corticosteroids market is segmented into
Pneumonia
Cepasia Syndrome
Human Respiratory syncytial virus (RSV) infection
Aureus Arthritis
Sinus Infection
Others
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Gaucher Disease Treatment Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2018-2026
Gaucher disease is an autosomal recessive inherited metabolism disorder where a type of fat (lipid) called glucocerebroside is unable to degrade. Body synthesis enzyme called glucocerebrosidase, which breakdowns and reprocesses glucocerebroside. Gaucher disease is caused by mutations of a single gene called GBA, which leads to very low levels of glucocerebrosidase enzyme leading to low degradation of glucocerebroside. There are three types of Gaucher disease namely: type 1, type 2, and type 3. Type 1 is the most common type of Gaucher disease while Type 2 and 3 are not as common as type 1.
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Approval of novel drugs is expected to boost growth of Gaucher disease treatment market
U.S. Food and Drug Administration (FDA) has approved multiple drugs in last few years for the treatment of disease. In 2010, FDA approved Vpriv (velaglucerase alfa), an enzyme replacement therapy (ERT), for type 1 Gaucher disease. In 2012, Elelyso (taliglucerase alfa) and in 2014, Cerdelga (eliglustat) was approved by FDA for type 1 Gaucher disease. These drugs offer variety of options based on their requirements, in turn is expected to boost the growth of the market.
In July 2017, The European Medicines Agency (EMA) and the United States Food and Drug Administration (FDA) collaborated to promote the use of innovative approaches in the development of medicines for Gaucher disease. Such strategic collaboration of regulatory bodies for the development of novel innovative drugs is expected to boost the growth of Gaucher disease treatment market in near future. Lack of awareness regarding the symptoms, diagnosis, and treatment of disease among rural population is a major factor restraining market growth.
North America is expected to hold dominant position due to increasing research activities and drug development for Gaucher disease
North America is expected to hold the dominant position in the Gaucher disease treatment market due to increasing research activities for the development of novel drugs. In 2016, the scientist from National Institutes of Health researchers collaborated with National Institute of Neurological Disorders and Stroke (NINDS) and the National Center for Advancing Translational Sciences (NCATS). Researchers identified a new molecule that shows promising approach for treatment of the rare Gaucher disease. Europe is expected to be the second largest market for Gaucher disease treatment due to the initiative taken by European organizations to spread awareness about Gaucher disease among the population. For instance in 2014, European Gaucher Alliance launched Gaucher Awareness Day aiming to spread awareness about this rare disease among the European population.
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Global Key Players:
Key players operating in global Gaucher disease treatment market include Genzyme Corporation, Pfizer, Inc., Shire Human Genetics Therapies, Inc., and Actelion Pharmaceuticals Ltd. (acquired by Johnson & Johnson in June 2017). There are various drugs in pipeline of companies such as Lixte Biotechnology Holdings Inc, JCR Pharmaceuticals Co Ltd, Pharming Group NV and Orphazyme ApS, for Gaucher disease treatment.
Gaucher Disease Treatment Market Taxonomy
The Gaucher disease treatment market is segmented on the basis of disease type, treatment type, and distribution channel.
On the basis of disease type, the Gaucher disease treatment market is segmented into:
Type 1 Gaucher disease
Type 2 Gaucher disease
Type 3 Gaucher disease
On the basis of therapy type, the Gaucher disease treatment market is segmented into:
Enzyme Replacement Therapy (ERT)
Substrate Reduction Therapy (SRT)
On the basis of distribution channel, the Gaucher disease treatment market is segmented into:
Hospitals
Retail Pharmacies
Online Pharmacies
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Medical Gas Analyzers Market - Global Industry Insights, Trends, Outlook and Opportunity Analysis, 2018-2026
Medical gas analyzers are used in hospital settings to keep a track of various gases that are used in different medical therapies. These medical gases include oxygen, carbon dioxide, nitrogen dioxide, and medical air. Medical gases have therapeutic advantages as it enables easy penetration through natural physiological barriers. Different gases have different therapeutic effects for various disease condition. Medical gases can be administered through inhalation, drinking hydrogen water, and through injections with hydrogen saturated saline.
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After administration in the system, the concentration of these gases is measured and analyzed so that patients’ condition is kept stabilized. Medical gas analyzers may be hand operated or automatic and they function on different methods such as optical, infrared, and electrochemical. Components of medical gas analyzers include pressure and flow regulators, pneumatic connexions, charging devices, filters, vacuum systems, and flow meters.
Advancements in technology in medical gas analyzers and increasing medical procedures are expected to boost the medical gas analyzers market growth
According to National Center for Health Statistics, 48 million surgical procedures were performed in the U.S. in 2009 and cardiovascular disease surgeries accounted for 7.3 million. The burden of diseases for is increasing rapidly, which is leading to increasing number of medical procedures. This has also fuelled growth of the medical gas analyzers market.
Applications of medical gas therapies in critical surgeries such as cerebrovascular and in cardiac strokes is another factor for growth of the market. Oxygen therapy is reported to be very effective and can be used in thermotoxicosis and hyperthermia. According to Centers for Disease Control and Prevention, 130,000 people in the U.S. die due to stroke each year and every year 795,000 of the population suffers from strokes indicating the need for medical gases for therapy in turn supporting growth of medical gas analyzers market. Medical gases have been proven effective in treatment of diseases such as cardiovascular, neurobiology, and respiratory inflammation in turn increasing the need for medical gases and analyzers.
Factors such as advancements in technology, new product launches, increasing prevalence of chronic diseases such as cancer, strokes, and respiratory diseases are expected to accelerate the medical gas analyzers market growth. New gas delivery techniques such as microbubbles and liposomes are expected to drive market growth.
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Medical Gas Analyzers Market Taxonomy:
The global medical gas analyzers market is segmented on the basis of analyzer type, by technology, end user, and geography
On the basis of analyzer type, the global medical gas analyzers market is segmented into:
Single Gas Analyzer
Multiple Gas Analyzer
On the basis of technology, the global medical gas analyzers market is segmented into:
Optical
Infrared
Electrochemical
On the basis of end user, global medical gas analyzers market is segmented into:
Hospitals
Ambulatory surgical centers
Diagnostic Centers
Research Institutes and Laboratories
Others
Regional segmentation of the Medical Gas Analyzers market by Coherent Market Insights comprises, North America, Europe, Latin America, Asia Pacific, Middle East, and Africa. North America market is expected to be dominant over the forecast period due to robust investment in healthcare infrastructure, competitors constantly striving to improve the technology and healthcare reimbursements. Asia Pacific market is expected to exhibit highest growth rate over the forecast period due to factors such as large customer base, local manufacturers producing low cost devices, increasing air pollution in countries such as Japan, India, and China. Government initiatives such as National Urban Health Mission (NUHM) and reducing stringency of government rules and regulations to set up hospitals in various Southern Indian States are expected to in turn aid in growth of the market.
Key Competitors
Competitors are focusing on continuous innovations and product launches and this is expected to aid in growth of the market. Gasera launched a new multiple gas analyzer in 2016. Furthermore, the company received US$ 2.74 million from the EU Horizon Framework Programme for development of modern analyzer capable of detecting hidden drugs and toxic substances.
Key players operating in the medical gas analyzers market include The Linde Group, Airgas, Praxair, Novair Medical, Matheson Tri-Gas, Air Products and Chemicals Inc., and Fluke Inc.
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Cardiac Marker Testing Devices Market - Global Industry Insights, Trends, Outlook and Opportunity Analysis, 2018-2026
Cardiac markers are diagnostic tool, which are associated for diagnosis and risk detection in patients suffering from chest pain, acute coronary syndrome (ACS), and acute myocardial infraction (MI). Cardiac marker test detects the endogenous substances, which are released during the blood circulation mainly when the heart is damaged or stressed, thereby, assessing risk and directing appropriate therapy that improves clinical outcome in high-risk patients. Cardiac markers are used in hospitals to either detect cardiac injury or to evaluate future risk of cardiovascular disease.
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Myoglobin, homocysteine, troponin T (cTnT), troponin I (cTnl), creatine kinase-MB (CK-MB), and C-reactive protein (CRP) are cardiac markers used for assessment of acute myocardial infraction. However, CK-MB, cTnl, and cTnT are used to identify and manage acute coronary syndrome in high-risk patients. Cardiac troponin I and T are most preferred and extensively used cardiac marker for myocardial injury, due to their higher sensitivity and specificity for diagnosis of myocardial infraction.
According to Journal of the American Medical Association (JAMA), in 2016, acute coronary syndrome is estimated as the major cause of morbidity and mortality worldwide. It is also responsible for over 1 million hospital admissions in the U.S. annually. Increasing incidence of myocardial infraction (MI) or heart attack, acute coronary syndrome, and consistent development in cardiac markers by existing market players are some of the factors fueling growth of the cardiac marker testing devices market. Moreover, high blood pressure, high LDL cholesterol, smoking, unhealthy diet, diabetes, obesity, physical inactivity, and excessive alcohol consumption are some other factors which cause coronary heart disease and associated disorders. This in turn, is expected to drive growth of the global cardiac marker testing devices market in the near future.
According to a report by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP), in 2016, around 47% of geriatric population in U.S. have at least one of three major risk factor of cardiovascular disease (CVD), which includes uncontrolled high blood pressure, uncontrolled high LDL cholesterol, and smoking. However, controlling these factors could reduce the risk of heart attack by 80%. BBI Solutions- a developer and manufacturer of raw material and finished test platforms for the in-vitro diagnostic tests, in 2017 announced to launch myoglobin antibiotics as a cardiac marker. These cardiac marker have been tested in ELISA assay before using it in commercial assay procedures and patient’s screening processes. The launch of new cardiac marker allows expansion of BBI solution’s antibodies portfolio in the global cardiac marker testing devices market.
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According to American Heart Association (AHA), around 790,000 people in U.S. have heart attack every year. Furthermore, an estimated annual incidence of heart attack in the U.S. are around 580,000 cases and 210,000 recurrent cases. According to AHA 2017 report, myocardial infraction diagnosis cost around US$ 11.5 billion and coronary heart disease cost around US$ 10.4 billion, were estimated as the most expensive hospital discharge diagnosis. The number of cardiovascular disease cases is expected to increase to 131.2 million by 2035, accounting to nearly 45% of the total U.S. population, with expected cost to reach US$ 1.1 trillion, which in turn, is expected to drive growth of the cardiac marker testing devices market.
Cardiac Marker Testing Devices Market Taxonomy:
By marker type:
Lactate Dehydrogenase
Creatine Kinase (CK)
CK-MM
CK-MB
CK-BB
Myoglobin
Natriuretic Peptides
Aspartate Aminotransferase (AST)
Cardiac Troponin
C-reactive Proteins
Others (galectin-3, myeloperoxidase, homocysteine, H-FABP, and ischemia-modified albumin)
By product type:
Instruments
Chemiluminescence
Immunofluorescence
Immunochromatography
ELISA
Reagents and kits
By application:
Acute Coronary Syndrome (ACS)
Myocardial Infraction (MI)
Cardiac Heart Failure
Others
By testing type:
Laboratory testing
Pont-of-care testing
By end user:
Hospitals
Diagnostic Laboratory
Home care setting
Major acquisitions are expected to drive growth of the cardiac marker testing devices market
In 2017, U.S. Federal Trade Commission (FTC) allowed US$ 5.3 billion of acquisition of Alere’s point-of-care cardiac marker testing business to Abbott Laboratories. The deal between Abbott Laboratories and Alere created the world’s largest point-of-care testing business, which significantly strengthen and grow Abbott’s diagnostic presence in cardiac marker testing devices market.
Moreover, in 2017, FTC approved the deal of Alere’s Triage B-type Naturietic Peptide (BNP) assay business and Triage MeterPro toxicology and cardiovascular business with Quidel Corporation. The acquisition of Alere’s point-of-care cardiac marker testing business is expected to improve Quidel’s portfolio of rapid diagnostic testing solutions.
Key players in the cardiac marker testing devices market
Some of the key players operating in the global cardiac marker testing devices market are Bio-Rad Laboratories, Inc., Siemens Medical Solutions USA, Inc., Randox Laboratories Ltd., Abbott Laboratories, Becton, Dickinson and Company, Helomics Corp., LSI Medience Corporation, F.Hoffmann-La Roche Ltd., Enzo Biochem Inc., Ortho Clinical Diagnostics, Danaher Corporation, and bioMerieux SA.
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Cardiac Monitoring Devices Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2018–2026
Cardiac monitoring devices enable continual observation of patients with heart disorders. These devices are commonly used in emergency rooms and critical care units and primarily in arrhythmias to monitor the rate of heartbeats. Common types of cardiac monitoring devices include holter monitors, event monitors, loop monitors, and insertable cardiac monitors. The additional parameters monitored noninvasively by cardiac monitors include blood pressure, cardiac output, intravascular pressures, arterial blood oxygen saturation, and blood temperature.
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Rise in incidence of cardiovascular diseases such as cardiac arrthymia, ischemic heart disease, and hypertension is expected to fuel growth of the cardiac monitoring devices market. According to World Health Organization (WHO), 2015, cardiovascular diseases was the leading cause of deaths accounting for 17.7 million deaths, globally. Furthermore, increasing applications of cardiac monitors in continuous monitoring for patients with severe electrolyte imbalances and for postoperative observation is expected to augment the market growth over the forecast period.
Development of technologically advanced cardiac monitoring devices is expected to boost the cardiac monitoring devices market growth over the forecast period
Development of advance cardiac monitoring devices such as remote cardiac monitoring devices and wireless cardiac monitoring devices providing early detection is a major factor expected to boast the cardiac monitoring devices market growth over the forecast period. For instance, ZywiePro, the next-generation cardiac remote monitoring solution launched in 2015, leverages mobile and cloud technology to facilitate detection of cardiovascular arrhythmias. ZywiePro enables physicians to provide more personalized and effective patient care by detailed diagnostic insight into the cardiovascular health of the patients. However, factors inhibiting the cardiac monitoring devices market include high cost of device and lack of knowledge about advance cardiac monitoring devices.
Advance cardiac monitoring devices enable physician to make accurate diagnosis and determine a treatment plan. For instance, the Reveal LINQ Insertable Cardiac Monitor manufactured by Medtronic, approved by FDA in 2014, is currently the smallest heart monitor in the market. It can diagnose the cause of infrequent, unexplained fainting spells better than conventional testing.
North America is expected to dominate the cardiac monitoring devices market over the forecast period, owing to increasing prevalence of cardiovascular diseases in the region
Regional segmentation of cardiac monitoring devices market by Coherent Market Insights comprises North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to hold a dominant position in global cardiac monitoring devices market over the forecast period, due to increasing prevalence of cardiovascular diseases in the region. According to the American Heart Association (AHA), 2017, about 92.1 million adults in the U.S. are suffering from some form of cardiovascular disease or the after-effects of stroke. AHA also stated in its report, that direct and indirect costs of cardiovascular diseases and stroke are estimated to account for US$ 316 billion, including health expenditures and lost productivity. Growth in Europe market is driven by emergence of innovative cardiac solutions offered by regional manufacturers and rising cases of cardiovascular diseases. For instance, LifeWatch —manufacturer of two innovative Mobile Cardiac Telemetry (MCT) solutions — LifeWatch MCT 3 Lead and LifeWatch MCT 1 Lead Patch detects, records, and wirelessly transmits asymptomatic and symptomatic arrhythmia to clinicians for analysis. According to European Heart Network and European Society of Cardiology 2015, over 85 million people suffer from cardiovascular disease (CVD) every year, causing over 4 million deaths in Europe.
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Asia Pacific is also expected to witness high growth. This is attributed to availability of technological advanced products and rising healthcare concern for stroke prevention associated with atrial fibrillation. According to the Japanese Heart Rhythm Society in 2017, the Asian population with atrial fibrillation (AF) is estimated to reach 72 million by 2050, of whom 2.9 million may suffer from AF-associated strokes.
Increasing FDA clearance for new and innovative products is a major factor fueling cardiac monitoring devices market growth
In 2016, the FDA approved wireless continuous non-invasive 'Beat-by-Beat' blood pressure and heart rate monitor manufactured by CareTaker Medical based on patented finger cuff technology. The device allows physicians to remotely monitor medical-grade continuous blood pressure and heart rate from anywhere, using only a patient friendly-finger cuff. Key players in cardiac monitoring devices market are Philips Healthcare, Medtronic, Boston Scientific, Cardiac Science, LifeWatch, CareTaker Medical, Spacelabs, St. Jude Medical, Kohden, CardioNet, and Mortara Instrument.
Market Taxonomy:
The global cardiac monitoring devices market is segmented on the basis of product type, application, end user, and geography.
On the basis of product type, the cardiac monitoring devices market in segmented into:
Holter Monitor
Event Monitor
Loop Monitor
Insertable Cardiac Monitor (ICM)
Mobile Cardiac Telemetry Devices
On the basis of application, the cardiac monitoring devices market in segmented into:
Arrhythmia
Coronary Artery disease
Hypertension
Ischemic Heart Disease
On the basis of end user, the cardiac monitoring devices market in segmented into:
Hospital
Diagnostic Centers
Ambulatory Surgical Centers
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Cannula Market – Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2018–2026
Cannula is a thin tube which is inserted in to the human body veins or body cavity to introduce medication, removal off fluid or to insert the surgical instrument. Cannula is usually surrounded by the trocar needle with inner and outer surface, which allows puncturing of the body in order to get enough space, it is also named as intravenous IV cannula. The normal cannulas size mainly ranges around 14 – 24 gauge. There are various types of cannula such as venous cannula, arterial cannula, nasal cannula or an oral-nasal cannula. The venous cannula is used for inserting in veins for the removal of blood samples and for administering medicines. An arterial cannula is used to insert in the artery of human body commonly in the radial artery during major operations such as bypass surgery and are also used to measure beat to beat blood pressure this is a painful procedure that leads to stress and anxiety. The nasal cannula or the oral nasal cannula used in the insertion into nostrils and mouth and also for delivering oxygen or to measure the airflow into the nose.
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On the basis of the sizes they are differentiate with colors such as orange (14G), grey (16G), green (18G), pink (20G), blue (22G), yellow (24G), violet (26G) this various sizes of cannula depends on the patient age, physique and the application of the cannula. Smaller gauge cannula as large diameter and the flow of fluid is faster. The materials that are used to make cannulas are plastic, metal and silicon as the silicon material is expected to support the growth of cannula market as this type of cannula are more flexible and soft to use.
Rise in general surgical procedures and increase in geriatric population around the globe expected to favor the demand for cannula market in the near future
North America is expected to contribute the major market share followed by Asia Pacific to the increase in the rate of geriatric population due to the increase in population size, increase in number of patients undergoing various surgical procedures and increase change in lifestyle related diseases such as obesity. Cannulas which are used in healthcare for surgical use in the major factor driving the growth of cannula market.
As per the data published by Organization for Economic Co-operation and Development (OECD), the geriatric population in 2014, was around 17.26% and 14.50% of the overall population in the U.K. and U.S. respectively, and the number is expected to increase steadily in the near future.
Also, the growth in number of surgical procedures around the globe expected to support the cannula market in the near future. As per the stats published by Organization for Economic Co-operation and Development (OECD), in 2014, around 814,969 total surgical procedures were performed around the globe. According to the American Society of Plastic (ASPS) in the U.S. there were around 15.9 million cosmetic surgeries were performed in the year 2015 were as the top 5 minimally invasive procedures such as soft tissue fillers was around 2.3 million and chemical peel were around 1.2million in 2014.
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Key players of cannula market includes:
Smith & Nephew, Maquel Holding B.V. & Co. KG., Sorin Group, Edward Lifescience Corporation, Medtronic plc, Terumo Corporation, Boston Scientific Corporation, Teleflex Incorporated, Conmed Corporation, Dolphin Surgicals, Micromed International, Goodhealth Inc., and Biotek (Chetan Meditech Pvt. Ltd.).
Cannula market taxonomy
Cannula Market by Type:
Cardiac cannula
Vascular cannula
Arthroscopy cannula
Dermatology cannula
Nasal cannula
Floating spinal cannulas
Vitreoretinal cannulas
Hysterosalpingography cannulas
Cannula Market by Application:
Cardiovascular Surgery
Oxygen Therapy
Orthopedic Surgery
Diabetes treatment
Neurology
General Surgery
Cosmetic/Plastic Surgery
Cannula Market by End-User:
Hospitals
Ambulatory Surgical Centers
Blood Banks
Home Healthcare Facilities
Cannula Market by Geography:
North America
Latin America
Europe
Asia Pacific
Middle East
Africa
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Apheresis Market – Global Industry Insights, Trends, Size, Share, Outlook, and Opportunity Analysis, 2018–2026
Apheresis is a procedure of blood purification and blood component separation by using centrifugation or membrane filtration technology. This procedure is performed for blood donation component or for the treatment of disease. In this procedure, the blood is extracted from the patient or from the donor’s body with the help of the apheresis machine and desired blood components are separated on the basis of their molecular size and weight. The remaining blood is transferred back to the patient’s or to the donor’s body. Apheresis procedure is performed for various diseases such as neurological, cardiovascular, renal, autoimmune, hematological and other diseases.
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The devices used in apheresis procedure are centrifugation and membrane filtration devices. The centrifuge therapeutic apheresis device is used in the separation of plasma or blood components from the whole blood. These devices are automated continuous-flow systems and are used to perform therapeutic plasma exchange, to remove plasma components or fluids, furthermore these devices are used to perform red blood cells exchange.
The various procedures performed in apheresis are plasma (plasmapheresis), platelets (plateletpheresis) and leukocytes (leukapheresis). Among these procedures, the plateletpheresis is the most common procedure performed for supplying human leukocyte antigen (HLA) platelets to the patient who have become HLA sensitized. In plasmapheresis procedure the plasma can be removed to supply blood components, such as red blood cells, white blood cells and platelets. The leukapheresis is the procedure in which white blood cells (WBC) are either separated or decreased from the blood sample of the patient for the blood cell count. It is also performed to obtain the patient's own blood cells for later transplant to use in chemotherapy treatments. The above reasons are expected to favor growth of the apheresis market.
Rise in incidence of chronic disease cases such as cancer inadvertently augments growth of the apheresis market. For instance, as per stats released by WHO, around 14 million new cases of cancer were reported in 2012. Plasma therapeutic products such as immunoglobulin, albumin, platelets and plasma are widely used for treatment of cancer.
The apheresis market has been segmented as follows:
Increase in number of chronic disease cases and blood donation rate around the globe expected to support the growth of therapeutic apheresis procedure market in the near future
North America is expected to contribute major market share in apheresis as increase in number of chronic disorders in this region, such as heart disease, diabetes and arthritis. As per Center for Disease Control and Prevention (CDC), in 2012, around 117 million adults were suffering from one or more chronic conditions. Furthermore, in the U.S., out of all adult population, 1 of 4 adult had 2 or more chronic health conditions.
Also, the high growth rate of therapeutic apheresis procedure is expected from Asia Pacific region in the near future, supported by rise in chronic disorder cases and due to unhealthy habits, such as feeding on junk food, physical inactivity and poor nutrition habits among rural population.
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Also, the increase in blood donation rate is projected to support the demand for therapeutic apheresis procedure market in the near future. As per World Health Organization (WHO), in 2013, 112.5 million blood donations were collected globally and around half of these were collected in the developed countries such as the U.S. and Canada.
Furthermore, the blood donation rate was around 35.0 per 1000 population in developed countries such as the U.S. and 11.7 per 1000 population in middle-income countries such as India and 4.6 per 1000 population in low-income countries such as Afghanistan. Also, the blood donations rate increased by 10.7 million in between 2008 to 2013.
Key Players In Apheresis Market Includes:
Some major companies operating in apheresis market are Kawasumi Laboratories Inc., NIKKISO CO. LTD., Therakos, Inc., Medica S.p.A., Asahi Kasei Medical Co. Ltd., Cerus Corporation, B. Braun, Melsungen AG, HemaCare Corporation, Haemonetics Corporation and Fresenius Kabi AG.
Apheresis Market, by Procedure:
Erythrocytapheresis
Leukapheresis
Plasmapheresis
Erythrocytapheresis
Photopheresis
LDL-apheresis
Apheresis Market, by Technology:
Membrane Filtration
Centrifugation
Apheresis Market, by Application:
Cancer
Autoimmune disease
Cardiovascular disease
Renal diseases
Neurology
Hematology
Apheresis Market, by Geography:
North America
Latin America
Europe
Asia Pacific
Middle East
Africa
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Medical Suction Units Market - Global Industry Insights, Trends, Size, Share, Outlook, and Opportunity Analysis, 2018–2026
Medical suction devices are important part of procedure followed in healthcare industry. It is essential for clinicians to have the reliable, accurate and safe medical suction devices in the hand. The accurate medical suction devices provide controllable suction level and enhances the safety requirements in hospital wards, operatory theaters, pathology laboratories, dental departments, mortuary, and postmortem rooms. The device is used to remove infectious material from wounds or some fluids from patient’s airways or respiratory system. The device might be used during the surgery in the operating room or at bedside of patients.
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The increasing prevalence of chronic respiratory diseases driving the medical suction units market
According to World Health Organization (WHO) facts sheet 2015, it was estimated that about 3 million people died due to chronic obstructive pulmonary disease (COPD), which is 5% of all deaths globally are caused by COPD. The increasing incidences of chronic respiratory diseases, such as chronic obstructive pulmonary diseases, asthma, and lung cancer is owing to increase the medical suction units market globally. The regulations provided by the government bodies driving the medical suction units market. For instance, the government bodies like Ministry of Health and Family Welfare (MOHFW), central Drugs standard control Organization (CDSCO) and Association of Indian Medical Device Industry (AIMED) providing the regulatory structure for medical devices, which has positive impact on the medical suction units industry. Advancements in technology help improve the medical devices, collaboration between companies producing the medical devices is boosting the growth of the medical suction units market. The portability, and user friendliness of some of the models of medical suction devices is enhancing its use in medical sector which is also helping to grow the market.
However, the high cost of the suction devices and reimbursement coverage for the homecare suction units are some of the restraints for the medical suction units market.
The adoption of technologically advanced medical devices in the patients will aid to boost the growth in the medical suction unit market
Regional segmentation of medical suction units market according to Coherent Market Insights comprises of North America, Europe, Asia Pacific, Latin America, Middle East, and Africa. The existence of leading market players, the presence of established healthcare infrastructure is helping North America region to dominate in the regional segment of medical suction unit market. Asia Pacific region is also one of the fastest growing markets for medical suction units. The growing trends in adoption of technologically advanced devices in the people, the untapped customers are some of the reasons which might help to drive the suction unit market in this region.
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The market players to focus on cost reduction and innovation to sustain in the highly fragmented medical suction units market globally
Key players operating the highly competitive medical suction units market includes Allied Healthcare Products Inc., Zoll medical Corporation, Amsino International Inc., Medicop, Precision Medical, SSCOR, Drive Medical, Learl Medical, INTEGRA biosciences, and others. The standard set by regulatory authorities like U.S. Food and Drug Administrations (FDA) for manufacturing of medical devices must be followed by the industries so that high quality product reach patients. For instance, the medical suction device can be used in dental, baby delivery, respiratory tract disease treatments, thus the suction units must be designed according to requirements, and this will be must for the industries to hold the medical suction units market. The market players such as Olympus Corporation, Drive Medical, and Siemens Healthcare GmbH are using the collaboration and partnership strategy to expand their market share.
The increasing homecare market and growing number of pre-hospital will help the dual powered units segment to grow in the future
The global medical suction units market is segmented on the basis of product type, portability, end user, and region
On the basis of product type,
AC-powered units
Battery powered units
Dual powered units
Manually operating units
On the basis of portability,
Hand-handled units
Wall-mounted units
On the basis of end user,
Clinics
Home Care Settings
Hospitals
Pre-Hospitals
Others
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ALK Positive Lung Cancer Treatment Market - Size, Share, Outlook, and Opportunity Analysis 2018 – 2026
ALK positive lung cancer treatment is used for people suffering from lung cancer with Anaplastic Lymphoma Kinase (ALK) mutation (the EML4-ALK fusion gene). This gene mutation is due to gene rearrangement by fusion of two genes called as ALK and Echinoderm Microtubule-associated protein Like 4 (EML4). The ALK gene fusion was first reported in 2007, in Non-small cell lung cancer (NSCLC) patients.
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ALK Positive Lung Cancer Treatment Market Drivers
New drug approvals for treatment of ALK positive lung cancer is expected to drive growth of the market. For instance, in August 2018, China National Drug Administration (CNDA) approved Alecensa (alectinib) of F. Hoffmann-La Roche Ltd., for treatment of ALK-positive lung cancer. Moreover, CNDA granted marketing authorization for Alecensa (alectinib), as monotherapy treatment for patients with anaplastic lymphoma kinase (ALK)-positive and advanced non-small cell lung cancer (NSCLC).
ALK Positive Lung Cancer Treatment Market Restraints
Development of rapid resistance to drugs is expected to limit growth of the ALK positive lung cancer treatment market. For instance, according to an Oncology Live February 2018 report, major challenge in drug development is rapid growth in resistance, which is responsible for slow patient recovery from disease. Moreover, according to an article published in Cancers journal, in August 2017, the mechanisms for resistance in drugs is tyrosine kinase mutations, and Epidermal Growth Factor Receptor (EGFR) activation. These bypass mechanisms of resistance are aggravating tumor cells, which in turn is restraining growth of the market.
ALK Positive Lung Cancer Treatment Market – Regional Analysis
On the basis of region, the global ALK positive lung cancer treatment market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America region is expected to witness significant growth in the market, owing to increasing number of clinical trials operating in the U.S. For instance, TP Therapeutics, Inc., is undergoing clinical trial for TPX-0005 drug for treating ALK mutations. The study is expected to complete in December 2021.
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Asia Pacific region is expected to witness the significant growth in the market, owing to increasing use of tobacco and smoking leading to lung cancer. According to an article published in Eastern Journal of medical Sciences 2017, lung cancer contributes around 6.8% of all cancers in India, representing the significant burden of lung cancer on country, which is contributing towards the cancer morbidity and mortality.
Global Key Players:
Key players operating in ALK positive lung cancer treatment market include F. Hoffmann-La Roche Ltd., Pfizer Inc., Novartis AG, TP Therapeutics, Inc., Bristol-Myers Squibb Company, and Eli Lilly and Company.
ALK Positive Lung Cancer Treatment Market – Taxonomy
By Drug
Crizotinib,Alectinib,Brigatinib,Ceritinib
By Distribution Channel
Hospital Pharmacies,Retail Pharmacies,Clinics
By Region
North America,Europe,Asia Pacific,Latin America,Middle East,Africa
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