#HighThroughputSequencing

[prateekcmi]

Next Generation Sequencing Revolutionizes Genomics Research

In the late 20th century, Sanger sequencing emerged as the dominant method for determining DNA sequences. However, Sanger sequencing had limitations as it was expensive, time-consuming and could sequence only a small number of DNA fragments in parallel. This changed in the early 2000s with the development of new DNA sequencing platforms that enabled high-throughput or "next-generation" sequencing. Pioneering companies like 454 Life Sciences, Illumina, Applied Biosystems and Helicos developed technologies that could sequence millions of DNA fragments in parallel. This massively increased sequencing output and allowed sequencing entire genomes rapidly and at a fraction of the cost compared to Sanger sequencing.

Get More Insights on Next Generation Sequencing   https://www.patreon.com/posts/promise-of-next-129589930    

[markscherz]

Thrilled to announce the description of one of the largest #frogs in #Madagascar, Mantidactylus radaka! It took a lot of sleuthing, including sequencing 120-year-old specimens, to be able to confidently describe this #newspecies! Its description was important, however, because these are among the frogs that are eaten by people in Madagascar, and they may be at risk of local over-harvesting, in additional to ongoing #deforestation and #habitatloss. You can find a link to get the PDF of the paper at http://www.markscherz.com/publications . . . . . . #science #taxonomy #systematics #museomics #taxonomcis #research #Mantidactylus #naturalhistory #herpetology #wildlife #animals #zoology #Mantellidae #rainforest #frog #diversity #peerreview #vertebrate #highthroughputsequencing #illumina #radaka #Malagasy #Sahona https://www.instagram.com/p/B_2LtWGgGyv/?igshid=ozlvb95cl13c