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[thxnews]

WHO Approves Safer Polio Vaccine for Children

WHO's Endorsement of nOPV2: A Leap in Child Health Safety

The World Health Organization (WHO) has recently prequalified the novel type 2 oral polio vaccine (nOPV2), a significant advancement in the global fight against polio. The safer Polio Vaccine was developed by a team including scientists from the Medicines and Healthcare Products Regulatory Agency (MHRA), this prequalification marks a crucial milestone in making the vaccine more accessible worldwide.  

MHRA's Pivotal Role in Developing nOPV2

After three years of Emergency Use Listing (EUL) and the successful distribution of 950 million doses globally, WHO's analysis confirmed nOPV2's strong safety profile and effectiveness. Dr. Andrew Macadam, a Principal Scientist at the MHRA, emphasized the continuous global threat of polio and the need for widespread immunization. This prequalification, according to Dr. Macadam, signifies a major step in increasing access to this safer vaccine, especially in developing countries.   Eradicating Polio: A Global Health Priority Polio, an infectious disease caused by the poliovirus, primarily affects children under five and can lead to permanent paralysis or death. The original oral polio vaccines (OPVs) have been instrumental in reducing polio cases by over 99% since 1988. However, the risk of vaccine-derived outbreaks remains in under-immunized populations, making the development and distribution of nOPV2 vital.  

nOPV2: A Safer Alternative in Polio Prevention

nOPV2 stands out for its reduced risk of causing vaccine-derived polio outbreaks. Unlike traditional OPVs, which can mutate and become harmful in low-immunization areas, nOPV2's genetic modifications significantly lower this risk. This makes it a safer and equally effective option for protecting against polio, especially in hard-to-reach regions.   Expanding Global Access to Polio Immunization The WHO's prequalification of nOPV2 not only endorses its safety and efficacy but also simplifies the process for member countries to obtain and use the vaccine. This eliminates the need for stringent readiness and monitoring requirements previously mandated under EUL, ensuring broader and long-term accessibility.  

A New Era in Polio Eradication

The WHO's decision to prequalify nOPV2 clearly demonstrates the need for a safer Polio Vaccine and the concerted efforts of global health organizations and scientists in combating polio. Significantly, it represents a major stride in ensuring children worldwide have access to safer and more effective immunization against this debilitating disease. Furthermore, this development is a key milestone in the ongoing journey to completely eradicate polio, ultimately safeguarding future generations from its impact.   Sources: THX News & Medicines and Healthcare products Regulatory Agency. Read the full article