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#L-polylactic acid (PLLA)
qingzinano · 2 years
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Electrospinning series you want to know - L-polylactic acid (PLLA)
Catalog:
1. Properties of PLLA materials
2. Application of PLLA nanofibers in tissue engineering
3. Experimental parameters of electrospun PLLA
4. Common problems and solutions
1. Properties of PLLA materials
Since there is an asymmetric carbon atom in the lactic acid molecule, which has optical activity, polylactic acid can also be divided into dextral polylactic acid (PDLA), left-handed polylactic acid (PLLA), racemic polylactic acid (PDLLA), and non optical polylactic acid (Meso PLA). PLA is an important biodegradable polymer material, characterized by non-toxic, non irritating, biodegradable absorption, high strength, good plasticity, and easy processing and molding. The degradation cycle is 2~12 months.
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Fig. 1 Enantiomeric form of lactic acid
2. Application of PLLA nanofibers in tissue engineering
PLLA is one of the first synthetic polymer materials recognized as suitable for tissue engineering due to its non-toxic, non irritating, biodegradable absorption and high strength. The nanofiber scaffold produced by the invention can be used for specific tissue engineering applications, including bone, cartilage, blood vessel and skin tissue regeneration.
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Fig. 2 Application of PLLA stent in tissue engineering
(1) Bone tissue
In bone tissue engineering, electrospinning has been widely used to prepare nanofiber scaffolds, whose structure is close to the nano collagen fibers of bone. In actual preparation, electrospun PLLA scaffold will be prepared in combination with surface modification to guide cells to differentiate into bone lineage and achieve the best bone regeneration performance.
A research team successfully modified the surface of PLLA nanofibers prepared by electrospinning through the surface deposition of osteogenic ECM. These scaffolds were then used to detect the response of mouse bone marrow stromal cells after implantation of the scaffold. The results showed that compared with pure PLLA nanofibers, the mineral growth, ALP activity and cell morphology of the modified structure were in the best state.
(2) Cartilage tissue
Although PLLA nanofiber scaffolds have shown significant effects on cartilage repair, their fine fibers lead to limited bearing capacity.
PLLA nanofiber scaffold made by phase separation and pore forming agent leaching has been proved to be the optimal scheme for cartilage repair in vivo and in vitro. This is due to the high porosity and interoperability of these scaffolds, as well as their good degradability. In addition, the appropriate size of the scaffold hole also improves the functional characteristics of cartilage, thus providing some different solutions for the regeneration and repair of cartilage tissue.
(3) Vascular tissue
Recently, a research team has made multi-layer scaffolds for vascular tissue engineering: PCL, collagen and PLLA nanofibers are used to simulate the inner membrane, middle membrane and outer membrane respectively. These nanofibers were made into three-layer tubular scaffolds by continuous electrospinning, and cultured endothelial cells and smooth muscle cells for biological activity evaluation. The final evaluation experiment results showed that the collagen in the middle layer significantly improved the adhesion and proliferation of SMC, and the proliferation of endothelial cells increased significantly with culture, indicating the non cytotoxicity of the construct.
(4) Skin tissue
In dermal fibroblasts culture in vitro, the mixed scaffold induced higher cell seeding efficiency and improved fibroblast adhesion and proliferation compared with collagen sponge. On the other hand, in vivo wound healing evaluation showed that the composite scaffold healed faster and more effectively than the collagen scaffold. In most cases, PLLA, collagen and gelatin are often combined to produce nanofiber scaffolds, which show physical and biological characteristics matching with skin substitutes.
PLLA is also used to produce multilayer scaffolds that are very similar to natural skin structures. A research team has developed a new type of double-layer scaffold, which is composed of chitosan/PCL nanofiber pad on the surface and PLLA microporous disk on the bottom. In this work, keratinocytes and fibroblasts were cultured as epidermal equivalent and dermal equivalent respectively. The final results showed that the cell proliferation in the double-layer scaffold was higher than that in the single-layer CP nano pad and PLLA microdisk. In addition, the evaluation of genes and proteins showed that the wound healing was active, which again confirmed that the double-layer scaffold could provide a suitable microenvironment for stimulating skin regeneration.
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Fig. 3 Small Aperture (125-250 μ m) In vitro cartilage differentiation of human bone marrow mesenchymal stem cells induced by β - lactamase scaffold Large specific aperture (425-600 μ m) The stents in our body better support cartilage formation.
Cited by: Capuana, E; Lopresti, F.;  Ceraulo, M.;  La Carrubba, V. Poly-l-Lactic Acid (PLLA)-Based Biomaterials for Regenerative Medicine: A Review on Processing and Applications.  Polymers 2022, 14, 1153.  https://doi.org/10.3390/polym14061153
3. Experimental parameters of electrospun PLLA
3.1 Experimental parameters for preparation of poly (L-lactide)/hydroxyapatite (PLLA/HA) nanocomposite scaffold
Material configuration: Dissolve 1g of PLLA (intrinsic viscosity 0.90-1.20dL/g) in 5mL of dichloromethane, and disperse 0.1g of nano HA powder (particle size<200nm) in the polymer solution under stirring, and transfer the obtained suspension to the medical syringe.
Electrospinning experiment parameters: positive voltage 15kV, liquid supply speed 1.5mL/h, needle 23G, spinning distance 15cm.
Reference: Rainer A, Spadaccio C, Sedati P, et al. Electrospun Hydroxapatite Functionalized PLLA Scaffold: Potential Applications in Sternal Bone Healing [J] Annals of Biomedical Engineering, 2011, 39(7):1882-1890.
3.2 Experimental parameters for preparation of PLLA/PCL oriented fiber scaffold
Material configuration: PLLA is dissolved in chloroform first, then in dimethylformamide (DMF) (4.25:0.75), while PCL is dissolved in chloroform/DMF (8:2). They were stirred for 3 hours, and then the polymer solution was loaded into the syringe by applying a positive voltage between the needle and the collector. The solution droplets leave the needle to form nanofibers and deposit at the same time. The percentage of PLLA/PCL is 47/53 wt%. The needle tip is placed 15 cm from the collector for PLLA and 20 cm for PCL, while rotating the disk at a linear rate set at 2800 rpm to collect parallel nanofibers.
Electrospinning test parameters: 5ml plastic syringe, 21 # needle, positive voltage (18 kV for PLLA, 24 kV for PCL)
Reference: Mashhadikhan M, Soleimani M, Parivar K, Yaghmaei P. ADSCs on PLLA/PCL Hybrid Nanoscaffold and Gelatin Modification: Cytocompatibility and Mechanical Properties Avicenna J Med Biotechnol.  2015 Jan-Mar; 7(1):32-8. PMID: 25926950;  PMCID: PMC4388888.
3.3 Experimental parameters for preparation of pure PLLA nanofibers
Material configuration: dissolve PLLA in hexafluoroisopropanol, with the mass fraction range of 8%~10%, 20G (1/2 inch, flat mouth) stainless steel needle, the needle is connected to the positive pole of high-voltage power supply, and the receiving roller is connected to the negative pole of high-voltage power supply
Electrospinning experiment parameters: the liquid supply speed is 0.5~3mL/h (depending on the electrospinning process), the roller speed is 300 rpm, the slide travel is 20cm, and the spinning voltage is positive 15kV and negative 5kV
4. Common problems and solutions
(1) The boiling point of the solvent is low, so it cannot be spun at high temperature to avoid the blockage of the needle tip due to the rapid evaporation of the solvent. 
(2) The solution shall be prepared by gradually adding particles or powders to prevent the dissolution rate from decreasing due to particle agglomeration and suspension.
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envil22100 · 1 year
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Middle East & Africa polylactic acid (PLA) market is expected to grow significantly in the forecast period of 2022 to 2029. Data Bridge Market Research analyses that the market is growing with a CAGR of 10.8% in the forecast period of 2022 to 2029 and is expected to reach USD 140,283.72 thousand by 2029.
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surajmarathedb1 · 2 years
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Polylactic Acid Market To Be Driven By The Rising Demand In The Industrial Sector In The Forecast Period Of 2022-2030
Polylactic Acid (PLA) can be synthesized by condensation as well as polymerization process. Polymerization technique is also known as ring-opening polymerization. It belongs to the family of aliphatic polyester commonly made from alpha-hydroxy acids and is considered as thermoplastic polyester. It possess superior characteristics such as biodegradability and recyclability, which make it suitable for the various end use applications such as consumer goods, electrical & electronics, automotive, textile, packaging, and others.
Polylactic Acid Market is projected to be worth USD 1500 Million by 2030, registering a CAGR of 16.3% during the forecast period (2021 - 2030).
Some of the prominent factors that positively influence the growth of Polylactic Acid Market are increasing demand for household appliances, improving standard of living, and rising consumption of PLA in consumer goods. Additionally, increasing production & sales in the automotive industry and shifting manufacturers focus towards manufacturing light weight and fuel-efficient vehicles are anticipated to propel the growth of the market over the forecast period 2021-2030. Furthermore, booming textile sector and rising trend of sportswear & attractive clothing in developed and developing countries are predicted to fuel the demand for Polylactic Acid during the review period.
Market Segmentation:
The Global Polylactic Acid Market is classified on the basis of type, application, and region.
On the basis of type, the market is categorized into PLLA (Poly-L-lactic Acid), PDLA (Poly-D-lactic Acid), PDLLA (Poly-DL-lactic Acid). All of them possess slightly different characteristics but are produced from renewable resource. On the basis of application, the market is categorized into automotive, textile, packaging, consumer goods, electrical & electronics, and others. Other applications include agriculture and pharmaceutical.  Among these, packaging holds the maximum share ~ 35% and is expected to continue its dominance over the forecast period on account of increasing awareness among consumers and plastic manufacturers regarding the environment. Growth in the production of passenger vehicles and heavy duty vehicles are expected to propel the lightweight automobile parts, likely to propel the Polylactic Acid Market growth. Additionally, the robust growth of the electrical & electronics industry in developing countries is estimated to fuel the growth of the market. Moreover, technological transfer from developed countries along with high consumer demand in emerging economies are responsible for upcoming new set ups in the packaging, automotive, textiles and electronics industries. 
Regional Analysis:
Europe is predicted to dominate the PLA market followed by North America and Asia Pacific due to increasing demand from electrical & electronics, textile, and consumer goods. In Europe, countries such as Germany, Spain, and the UK are expected to dominate the regional market share due to significant demand from prominent automobile manufacturers. North America PLA market is estimated to witness a moderate growth since the U.S, Canada, and Mexico are the major contributors due to improving health care sector and expanding automotive sector. Numerous countries of Asia Pacific such as India, China, Vietnam, Malaysia, and South Korea are the fastest growing PLA market across the globe, and is estimated to grow with the same pace over the assessment period. Various factors that are attributed to the growth of the market in Asia Pacific are rising middle class population, increasing number of working professionals, competitive manufacturing costs, and ease in availability of raw material.
Competitive Analysis:
The major players operating in the Polylactic Acid Market are BASF SE (Germany), The DOW Chemical Company (U.S.), Corbion (the Netherlands), TEIJIN LIMITED. (Japan), NatureWorks LLC (U.S.), Synbra Technology bv (the Netherlands), Galactic (Belgium), Sulzer Ltd (Switzerland), Hitachi, Ltd. (Japan), Musashino Chemical Laboratory, Ltd. (Japan), and others.
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thetejasamale · 3 years
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Polylactic Acid Market Growth | Segments, Size, Share, Trends, Demand, Key Player profile and Regional Outlook by 2030
Polylactic Acid (PLA) can be synthesized by condensation as well as polymerization process. Polymerization technique is also known as ring-opening polymerization. It belongs to the family of aliphatic polyester commonly made from alpha-hydroxy acids and is considered as thermoplastic polyester. It possess superior characteristics such as biodegradability and recyclability, which make it suitable for the various end use applications such as consumer goods, electrical & electronics, automotive, textile, packaging, and others.
Some of the prominent factors that positively influence the growth of Polylactic Acid Market are increasing demand for household appliances, improving standard of living, and rising consumption of PLA in consumer goods. Additionally, increasing production & sales in the automotive industry and shifting manufacturers focus towards manufacturing light weight and fuel-efficient vehicles are anticipated to propel the growth of the market over the forecast period 2017-2023. Furthermore, booming textile sector and rising trend of sportswear & attractive clothing in developed and developing countries are predicted to fuel the demand for Polylactic Acid during the review period.
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Competitive Analysis:
The major players operating in the Polylactic Acid Market are BASF SE (Germany), The DOW Chemical Company (U.S.), Corbion (the Netherlands), TEIJIN LIMITED. (Japan), NatureWorks LLC (U.S.), Synbra Technology bv (the Netherlands), Galactic (Belgium), Sulzer Ltd (Switzerland), Hitachi, Ltd. (Japan), Musashino Chemical Laboratory, Ltd. (Japan), and others.
Market Segmentation:
The Global Polylactic Acid Market is classified on the basis of type, application, and region. On the basis of type, the market is categorized into PLLA (Poly-L-lactic Acid), PDLA (Poly-D-lactic Acid), PDLLA (Poly-DL-lactic Acid). All of them possess slightly different characteristics but are produced from renewable resource. On the basis of application, the market is categorized into automotive, textile, packaging, consumer goods, electrical & electronics, and others. Other applications include agriculture and pharmaceutical.  Among these, packaging holds the maximum share ~ 35% and is expected to continue its dominance over the forecast period on account of increasing awareness among consumers and plastic manufacturers regarding the environment. Growth in the production of passenger vehicles and heavy duty vehicles are expected to propel the lightweight automobile parts, likely to propel the Polylactic Acid Market growth. Additionally, the robust growth of the electrical & electronics industry in developing countries is estimated to fuel the growth of the market. Moreover, technological transfer from developed countries along with high consumer demand in emerging economies are responsible for upcoming new set ups in the packaging, automotive, textiles and electronics industries.
Access Complete Report @ https://www.marketresearchfuture.com/reports/polylactic-acid-market-4557
Regional Analysis:
Europe is predicted to dominate the PLA market followed by North America and Asia Pacific due to increasing demand from electrical & electronics, textile, and consumer goods. In Europe, countries such as Germany, Spain, and the UK are expected to dominate the regional market share due to significant demand from prominent automobile manufacturers. North America PLA market is estimated to witness a moderate growth since the U.S, Canada, and Mexico are the major contributors due to improving health care sector and expanding automotive sector. Numerous countries of Asia Pacific such as India, China, Vietnam, Malaysia, and South Korea are the fastest growing PLA market across the globe, and is estimated to grow with the same pace over the assessment period. Various factors that are attributed to the growth of the market in Asia Pacific are rising middle class population, increasing number of working professionals, competitive manufacturing costs, and ease in availability of raw material.
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contactvishalkadu · 4 years
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Bioresorbable Implants Market - Global Forecast to 2026
BIORESORBABLE IMPLANTS MARKET ANALYSIS
By Material Type (Metallic and Polymer), by Application (Orthopedic, Cardiovascular, and Others), by End User (Hospitals, Ambulatory Surgical Centers, and Others), and by Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) - Size, Share, Trends, and Forecast to 2026
Bioresorbable implants are prosthetic in nature and are made from polymer having a property to gradually decompose with the passage of time. It is used to support, enhance, and regularize the physiological function in the human body. Different types of material used in bioresorbable implants are Poly lactic-co-glycolic acid (PLGA), Poly L-lactide (PLLA), and others. The PLGA bioresorbable implant are actively used in periodontal therapy.
Market Dynamics
Increasing prevalence of trauma injuries, osteoporosis, and cardiovascular diseases is a major factor driving bioresorbable implants market growth. According to World Health Organization (WHO) factsheet in 2018, annually there are around 37.3 million falls, which require medical attention whereas an estimated 646,000 individuals die annually from falls globally. Moreover, advantages of bioresorbable polymer implants over metallic implants are expected to boost the market growth. Bioresorbable implants degrade after completion of its function, which is considered as the major advantage of bioresorbable implants over the permanently installed devices. Bioresorbable implants also bypasses the need of second surgery for the removal of the implant, making the process cost effective as compared to the non-biodegradable implants. However, bare metal implants or inert metallic implants lead to serious and life threating conditions such as neoatherosclerosis, late stent thrombosis, and local inflammation due to the presence of a foreign body.
Key features of the study:
This report provides in-depth analysis of the bioresorbable implants market and provides market size (US$ million) and Compound Annual Growth Rate (CAGR %) for the forecast period (2018 – 2026), considering 2017 as the base year
It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends,  regional outlook, and competitive strategy adopted by key players
It profiles key players in the global bioresorbable implants market based on the following parameters – company overview, financial performance, product portfolio, market presence, distribution strategies, key developments, strategies, and future plans
Key companies covered as a part of this study include, Bioretec Ltd., CONMED Corporation, Depuy Synthes, Stryker Corporation, Zimmer Biomet Holdings, Inc., Smith & Nephew Plc., and Boston Scientific Corporation.
Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, technology up-gradation, market expansion, and marketing tactics.
The global bioresorbable implants market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the bioresorbable implants market
Detailed Segmentation:
PLGA- Poly lactic-co-glycolic acid
PLLA- Poly L-lactide
PGA- Polyglycolic Acid
PLA- Polylactic Acid
Others
Orthopedic
Cardiovascular
Others
Hospitals
Ambulatory Surgical Centers
Others
PLGA- Poly lactic-co-glycolic acid
PLLA- Poly L-lactide
PGA- Polyglycolic Acid
PLA- Polylactic Acid
Others
Orthopedic
Cardiovascular
Others
Hospitals
Ambulatory Surgical Centers
Others
U.S.
Canada
PLGA- Poly lactic-co-glycolic acid
PLLA- Poly L-lactide
PGA- Polyglycolic Acid
PLA- Polylactic Acid
Others
Orthopedic
Cardiovascular
Others
Hospitals
Ambulatory Surgical Centers
Others
Brazil
Mexico
Argentina
Rest of Latin America
PLGA- Poly lactic-co-glycolic acid
PLLA- Poly L-lactide
PGA- Polyglycolic Acid
PLA- Polylactic Acid
Others
Orthopedic
Cardiovascular
Others
Hospitals
Ambulatory Surgical Centers
Others
Germany
U.K.
France
Italy
Spain
Russia
Rest of Europe
PLGA- Poly lactic-co-glycolic acid
PLLA- Poly L-lactide
PGA- Polyglycolic Acid
PLA- Polylactic Acid
Others
Orthopedic
Cardiovascular
Others
Hospitals
Ambulatory Surgical Centers
Others
China
India
Japan
Australia
South Korea
ASEAN
Rest of Asia Pacific
PLGA- Poly lactic-co-glycolic acid
PLLA- Poly L-lactide
PGA- Polyglycolic Acid
PLA- Polylactic Acid
Others
Orthopedic
Cardiovascular
Others
Hospitals
Ambulatory Surgical Centers
Others
Ambulatory Surgical Centers
Specialty Clinics
GCC
Israel
Rest of Middle East
PLGA- Poly lactic-co-glycolic acid
PLLA- Poly L-lactide
PGA- Polyglycolic Acid
PLA- Polylactic Acid
Others
Orthopedic
Cardiovascular
Others
Hospitals
Ambulatory Surgical Centers
Others
South Africa
Central Africa
North Africa
Company Overview
Product Portfolio
Financial Performance
Key Highlights
Market Strategies
“*” marked represents similar segmentation in other categories in the respective section.
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ratiram · 5 years
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According to study, “World Polylactice Acid (PLA) Market Research Report 2024(Covering USA, EU, China, South East Asia, Japan and etc)” the key companies operating in the world polylactice acid market areNatureWorks LLC, BASF SE, Teijin Ltd., Thyssenkrupp AG, Synbra Technology B.V, Zhejiang Hisun Biomaterials Co., Ltd., Uhde Inventa-Fischer, Danimer Scientific, Sulzer Ltd., Yangtzelabre, Jiuding Biological Engineering, Shenzhen Esun Industrial, Corbion, Hitachi Ltd., Futerro, Shanghai Tongjieliang. Key companies are undertaking many initiatives for instance product accreditation and strengthening product length to increase its performance over the coming years.
Polylactic acid or PLA is a type of thermoplastic aliphatic polyester produced from wide variety of renewable feedstock for instance wheat, corn, starch, sugarcane and tapioca roots. It is made through two different processes such as condensation and polymerization. It is soluble in solvents, tetrahydrofuran, hot benzene, and dioxane. It is eco-friendly as well as biocompatible in nature. It is used to produce microwaveable containers and engineering plastics such as food containers and disposable cutlery. The key properties are better aesthetic appeal, better printability and good resistance to oil & grease.
Based on type, polylactice acid market is segmented into PLLA (Poly-L-lactic Acid), PDLLA (Poly-DL-lactic Acid) and PDLA (Poly-D-lactic Acid). Based on raw material, market is segmented into sugarcane, cassava, corn, and other crops (wheat, potato, rice, and sweet sorghum). Sugarcane segment is estimated to witness a high demand during the forecast years owing to various research & development (R&D) initiatives conducted in order to extend innovative manufacturing processes to support the manufacture of bioplastics & biochemical made from sustainable feedstock. In addition, based on application, market is segmented into transport, packaging (food & beverages), textile, electrical & electronics, consumer goods, and others. Packaging segment holds major share due to increase in consumer awareness regarding the need to decrease dependency of fossil fuel reserves.
The polylactice acid market is driven by growth in demand for flexible packaging market, followed byincrease in demand for bioplastics packaging, rise in demand for cellulose derived fibers in textile industry, easy availability of raw materials, increase in personal or skin care industry, rise in drug manufacturing, introduction of innovative products, increase in consumption of biodegradable polymers, presence of leading manufacturing companies, rise in use of the product in shopping bags & disposable cutlery, growth in composting infrastructure, inherent features such as flavor and odor barrier characteristics, increase in technological advancement, government incentives and rise in consumer preference towards green packaging& recyclability. However, inferior performance compared to conventional plastics and price competitiveness may impact the market. Moreover, rise in usage D printing and growth in production of genetically modified corn are key opportunities for market.
Based on geography, EU holds major share in polylactice acid market owing to implementation of strict regulations by government body for instance REACH and continuous growth in transportation sector in the region. China, Japan and USA countries are expected to witness higher growth rate due to rise in production facilities, large production capacity, supportive legal framework, feedstock abundancy, and rise in consumer awareness for sustainability over the forecast period. It is anticipated that future of the market will be bright on account of rise in demand for packaged foods including ready-to-eat meals and frozen meals.
For more information on the research report, refer to below link:
Global Polylactice Acid (PLA) Market
Related reports
Polylactice Acid (PLA) Market Research: Global Status & Forecast by Geography, Type & Application (2015-2025)
World Polylactice Acid (PLA) Market Research Report 2024
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Polylactic Acid Market Size, By Regional Outlook Research Report, Services by Application Forecast To 2023
Polylactic Acid Market - Overview
Global polylactic acid or PLA demand is expected to remain moderate over the next couple of years. Market Research Future (MRFR) projects that the global polylactic acid market will witness a steady growth during the review period (2017-2023). The majority of the polylactic acid produced is derived from renewable feedstock such as corn, wheat, sugarcane, tapioca roots and starch. Production procedures may vary; however, polymerization and condensation remain the two core techniques.  
The Global Polylactic Acid Market include continuous growth of the automotive industry, rapid urbanization, and increasing demand for biodegradable plastic. Furthermore, polylactic acid Market is being applied in packaging industry which propels the growth of the market over the forecast period. The introduction of bio-based plastics and their increased usage in the electrical & electronics industry, increasing production of passenger cars and rising disposable income of consumer in developing economies drives the growth of the polylactic acid market.
Competitive Landscape:
Some of the prominent players operating in the Global Polylactic Acid Market are BASF SE (Germany), The DOW Chemical Company (U.S.), Corbion (the Netherlands), TEIJIN LIMITED. (Japan), NatureWorks LLC (U.S.), Synbra Technology bv (the Netherlands), Galactic (Belgium), Sulzer Ltd (Switzerland), Hitachi, Ltd. (Japan), Musashino Chemical Laboratory, Ltd. (Japan), and others.
Market Segmentation:
The global polylactic acid market is segmented based on type and application.
Based on type, the market is segmented into PLLA (poly-L-lactic acid), PDLA (poly-D-lactic acid), and PDLLA (poly-DL-lactic acid).
Based on application, the market is segmented into automotive, textile, packaging, consumer goods, electrical & electronics, and others. Because of better wicking, drape and excellent crease resistance polylactic can be used in various applications like wipes, and geotextiles, etc. It has a good UV resistance and superior resilience which brings its application in furnishing like carpet tiles, industrial wall panels, automotive furnishing.
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Industry Overview:
The Dow Chemical Co. is expanding into eastern Canada with its first new sales center with the new Toronto office allowing the company to get closer to its customers and collaborate better as it gears up for growth after its planned spin-off from Midland-based DowDuPont Inc. early next year (2019).
Regional Analysis:
The global polylactic acid market consists of five regions which are Asia Pacific, Europe, Latin America, North America, and the Middle East and Africa. Among these regions, the Asia Pacific region is estimated to surge at the highest CAGR over the estimated period 2019-2023 attributed to stable economy and continuous growth of the automotive as well as packaging industry.
The market is expected to remain somewhat profitable in regions such as North America and Europe. Unlike APAC, market opportunities will remain slim in the West. The rapid shift of manufacturing to developing countries owing higher cost-benefits may have its ramifications on the market scope in advanced countries.
In North America, most of the contribution in terms of revenue comes from the U.S. and this trend is expected to continue throughout the forecast period. Meanwhile, Mexico is likely to gain a healthy ground owing to the fast expansion of the manufacturing sector in the country.
List Of Tables:
Table 1 World Population By Major Regions (2016 To 2023)
Table 2 Global Polylactic Acid Market: By Region, 2016-2023
Table 3 North America Polylactic Acid Market: By Country, 2016-2023
Table 4 Europe Polylactic Acid Market: By Country, 2016-2023
Table 5 Asia-Pacific Polylactic Acid Market: By Country, 2016-2023
To Be Continue………
List Of Figures:
FIGURE 1 Global Polylactic Acid Market Segmentation
FIGURE 2 Forecast Methodology
FIGURE 3 Five Forces Analysis Of Global Polylactic Acid Market
FIGURE 4 Value Chain Of Global Polylactic Acid Market
To Be Continue………
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hyfpack-blog · 5 years
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POLYLACTIC ACID PROPERTIES, PRODUCTION
Poly lactic acid (PLA) is kind of biodegradable thermoplastic derived from renewable sources including corn starch (majorly in U.S & Canada), cassava roots, chips, starch (in Asia) or even from sugarcane (in the rest of the world).
What is Polylactic Acid (PLA)?
PLA material is different from the commonly available form of thermoplastic polymer materials. It is primarily derived from renewable resources like corn starch or sugar cane.
Mostly plastics are derived through a common process termed as polymerization utilizing the non-renewable sources of energy. However, PLA plastic is a form of bioplastic derived from biomass.
It is a kind of biodegradable plastic with the characteristics similar to all other polymers such as Polypropylene (PP), Polyethylene terephthalate or Acrylonitrile Butadiene Styrene (ABS)
Poly lactic acid is applicable for a variety of uses including the production of plastic films, plastic bottles and medical devices (biodegradable in nature). It is even used 3D printing along with producing objects to hold hot liquids (e.g. cups).
Different Types of Polylactic acid
There are many types of polylactic acid available including Racemic PLLA (Poly-L-lactic Acid), Regular PLLA (Poly-L-lactic Acid), PDLA (Poly-D-lactic Acid), and PDLLA (Poly-DL-lactic Acid).
Each of them is slightly different in their characteristics but are produced in a similar way from renewable sources (lactic acid).
History of Polylactic Acid
PLA was first discovered by Wallace Carothers (who also invented nylon) in 1920. He was aiming to produce an environmentally-friendly plastic for DuPont. In initial days the commercial use of PLA material was very costly.
Further, in 1989 Dr. Patrick R. Gruber along with his wife Sally, discovered the process of producing this material by corn on his stove at home, which reduced the manufacturing cost.
Nowadays this is the most commonly used environment-friendly thermoplastic at the global level.
How is Polylactic Acid Produced?
This material is produced by usage of two basic monomers which are lactic acid and lactide (cyclic de-ester). Two different processes are involved in producing PLA are condensation and polymerization.
The most commonly used process is polymerization process. It is termed as ring-opening polymerization of lactide with various metal catalysts (tin octane) in solution, melt form or even as suspension. This process results in metal catalyst combining with lactide to form larger pla molecules.
The condensation process is very similar to the polymerization process. The principal difference in both the processes is temperature during the process and the by-products (condensates) released after the reaction.
This process is carried out at less than 200°C, as above this temperature entropically favored lactide is generated. At initial level of the process lactic acid is first oligomerized to PLA oligomers. Afterwards, poly-condensation is done in melt or solution where short oligomers combine and produce high molecular weight PLA.
Properties of Polylactic Acid
PLA plastic biodegradable nature and suiting optical, physical and chemical properties prove it to be an ideal choice of material for a number of applications including dyeing for textiles, packaging, medical devices (stents & sutures) even for diapers and many others.
Basic Properties Include:
● High mechanical strength
● Low toxic level
● Good Barrier properties (moisture, heat etc.)
● High mechanical resistance
● Good and smooth appearance
● Resistant to chemicals
● UV resistant
● Low flammability & smoke formation
Physical Properties of Poly Lactic Acid:
● PLA Density- 1.210–1.430 g·cm−3 [1]
● Melting Point- 150 to 160 °C (302 to 320 °F; 423 to 433 K)[1]
● Specific Gravity- 1.27
● Glass Transition Temperature- 55°C
Mechanical Properties of Poly Lactic Acid:
● Tensile Strength- 59MPa
● Flexural Strength- 106MPa
● Elongation at break- 7.0%
● Rockwell Hardness- 88HR
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Video
**T H R E A D L I F T** Theadlifting is an awesome option for those of you who want to LIFT without needing the extra volume! Threadlifting is another non-surgical solution to enhance your beauty by lifting areas that have descended due to the natural aging process. Most threads are made of PLLA (polylactic acid) or PDO (polydiaxanone) which are complex sugar compounds that the body slowly dissolves over time. The results are immediate, and they continue to improve as the body produces its own collagen to surround the inserted threads. It usually takes 6-8 months for the threads to fully dissolve, but the lift remains for an average of 12 months due to new collagen formation. Although threadlifting does not replace surgery, it is a great noninvasive alternative with minimal discomfort and downtime!! (at Bella Tu Med Spa) https://www.instagram.com/p/BqqneFKAQf5/?utm_source=ig_tumblr_share&igshid=1c5xnvgdxo3if
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surajmarathedb1 · 2 years
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Polylactic Acid Market Share, Growth by Manufacturers, Revenue, Demand, Segments and Forecast 2030
Polylactic Acid (PLA) can be synthesized by condensation as well as polymerization process. Polymerization technique is also known as ring-opening polymerization. It belongs to the family of aliphatic polyester commonly made from alpha-hydroxy acids and is considered as thermoplastic polyester. It possess superior characteristics such as biodegradability and recyclability, which make it suitable for the various end use applications such as consumer goods, electrical & electronics, automotive, textile, packaging, and others.
Some of the prominent factors that positively influence the growth of Polylactic Acid Market Share are increasing demand for household appliances, improving standard of living, and rising consumption of PLA in consumer goods. Additionally, increasing production & sales in the automotive industry and shifting manufacturers focus towards manufacturing light weight and fuel-efficient vehicles are anticipated to propel the growth of the market over the forecast period 2017-2023. Furthermore, booming textile sector and rising trend of sportswear & attractive clothing in developed and developing countries are predicted to fuel the demand for Polylactic Acid during the review period.
Market Segmentation:
The Global Polylactic Acid Market Share is classified on the basis of type, application, and region.
On the basis of type, the market is categorized into PLLA (Poly-L-lactic Acid), PDLA (Poly-D-lactic Acid), PDLLA (Poly-DL-lactic Acid). All of them possess slightly different characteristics but are produced from renewable resource. On the basis of application, the market is categorized into automotive, textile, packaging, consumer goods, electrical & electronics, and others. Other applications include agriculture and pharmaceutical.  Among these, packaging holds the maximum share ~ 35% and is expected to continue its dominance over the forecast period on account of increasing awareness among consumers and plastic manufacturers regarding the environment. Growth in the production of passenger vehicles and heavy duty vehicles are expected to propel the lightweight automobile parts, likely to propel the Polylactic Acid Market Share growth. Additionally, the robust growth of the electrical & electronics industry in developing countries is estimated to fuel the growth of the market. Moreover, technological transfer from developed countries along with high consumer demand in emerging economies are responsible for upcoming new set ups in the packaging, automotive, textiles and electronics industries.
Regional Analysis:
Europe is predicted to dominate the PLA market followed by North America and Asia Pacific due to increasing demand from electrical & electronics, textile, and consumer goods. In Europe, countries such as Germany, Spain, and the UK are expected to dominate the regional market share due to significant demand from prominent automobile manufacturers. North America PLA market is estimated to witness a moderate growth since the U.S, Canada, and Mexico are the major contributors due to improving health care sector and expanding automotive sector. Numerous countries of Asia Pacific such as India, China, Vietnam, Malaysia, and South Korea are the fastest growing PLA market across the globe, and is estimated to grow with the same pace over the assessment period. Various factors that are attributed to the growth of the market in Asia Pacific are rising middle class population, increasing number of working professionals, competitive manufacturing costs, and ease in availability of raw material.
Competitive Analysis:
The major players operating in the Polylactic Acid Market Share are BASF SE (Germany), The DOW Chemical Company (U.S.), Corbion (the Netherlands), TEIJIN LIMITED. (Japan), NatureWorks LLC (U.S.), Synbra Technology bv (the Netherlands), Galactic (Belgium), Sulzer Ltd (Switzerland), Hitachi, Ltd. (Japan), Musashino Chemical Laboratory, Ltd. (Japan), and others.
Access Complete Report @ https://www.marketresearchfuture.com/reports/polylactic-acid-market-4557
NOTE: Our team of researchers are studying Covid19 and its impact on various industry verticals and wherever required we will be considering covid19 footprints for a better analysis of markets and industries. Cordially get in touch for more details.
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thetejasamale · 3 years
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Polylactic Acid Market- Key Player profile, Regional Outlook, Size, Growth, Trends, Demand, and Industry Analysis by 2030
Polylactic Acid (PLA) can be synthesized by condensation as well as polymerization process. Polymerization technique is also known as ring-opening polymerization. It belongs to the family of aliphatic polyester commonly made from alpha-hydroxy acids and is considered as thermoplastic polyester. It possess superior characteristics such as biodegradability and recyclability, which make it suitable for the various end use applications such as consumer goods, electrical & electronics, automotive, textile, packaging, and others.
Some of the prominent factors that positively influence the growth of Polylactic Acid Market are increasing demand for household appliances, improving standard of living, and rising consumption of PLA in consumer goods. Additionally, increasing production & sales in the automotive industry and shifting manufacturers focus towards manufacturing light weight and fuel-efficient vehicles are anticipated to propel the growth of the market over the forecast period 2017-2023. Furthermore, booming textile sector and rising trend of sportswear & attractive clothing in developed and developing countries are predicted to fuel the demand for Polylactic Acid during the review period.
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Competitive Analysis:
The major players operating in the Polylactic Acid Market are BASF SE (Germany), The DOW Chemical Company (U.S.), Corbion (the Netherlands), TEIJIN LIMITED. (Japan), NatureWorks LLC (U.S.), Synbra Technology bv (the Netherlands), Galactic (Belgium), Sulzer Ltd (Switzerland), Hitachi, Ltd. (Japan), Musashino Chemical Laboratory, Ltd. (Japan), and others.
Market Segmentation:
The Global Polylactic Acid Market is classified on the basis of type, application, and region. On the basis of type, the market is categorized into PLLA (Poly-L-lactic Acid), PDLA (Poly-D-lactic Acid), PDLLA (Poly-DL-lactic Acid). All of them possess slightly different characteristics but are produced from renewable resource. On the basis of application, the market is categorized into automotive, textile, packaging, consumer goods, electrical & electronics, and others. Other applications include agriculture and pharmaceutical.  Among these, packaging holds the maximum share ~ 35% and is expected to continue its dominance over the forecast period on account of increasing awareness among consumers and plastic manufacturers regarding the environment. Growth in the production of passenger vehicles and heavy duty vehicles are expected to propel the lightweight automobile parts, likely to propel the Polylactic Acid Market growth. Additionally, the robust growth of the electrical & electronics industry in developing countries is estimated to fuel the growth of the market. Moreover, technological transfer from developed countries along with high consumer demand in emerging economies are responsible for upcoming new set ups in the packaging, automotive, textiles and electronics industries.
Access Complete Report @ https://www.marketresearchfuture.com/reports/polylactic-acid-market-4557
Regional Analysis:
Europe is predicted to dominate the PLA market followed by North America and Asia Pacific due to increasing demand from electrical & electronics, textile, and consumer goods. In Europe, countries such as Germany, Spain, and the UK are expected to dominate the regional market share due to significant demand from prominent automobile manufacturers. North America PLA market is estimated to witness a moderate growth since the U.S, Canada, and Mexico are the major contributors due to improving health care sector and expanding automotive sector. Numerous countries of Asia Pacific such as India, China, Vietnam, Malaysia, and South Korea are the fastest growing PLA market across the globe, and is estimated to grow with the same pace over the assessment period. Various factors that are attributed to the growth of the market in Asia Pacific are rising middle class population, increasing number of working professionals, competitive manufacturing costs, and ease in availability of raw material.
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Global Biodegradable Stents Market to Surpass US$ 0.8 Billion by 2026
Stents are metal scaffolds used for opening the blocked vessel to optimize the flow of biliary fluid or blood through the vessel. Biodegradable stents also called as bioresorbable stents are type of stents made from special biodegradable material such as polymers and metal, eliminating the stents removal and side-effects of conventional stents. Biodegradable polymers evaluated for stent manufacture are polylactic acid (PLA), poly-DL-lactic acid (PDLLA), poly-L-lactic acid (PLLA), poly-DL-lactide-co-glycolide (PDLGA), poly-lactic-co glycolide (PLGA), polycaprolactone (PCL), polylactic acid/polycaprolactone (PLA/PCL), whereas biodegradable metal are made up of magnesium, stainless steel, and cobalt chromium. Biodegradable material hydrolyze in presence of water and convert into simple biological compounds.
Click To Continue Reading on Global Biodegradable Stents Market
High risk of developing cardiovascular disease is expected to fuel the biodegradable stents market growth over the forecast period. For instance, according to American Heart Association, cardiovascular disease is a leading cause of death worldwide, owning for more than 17.3 million deaths per year in 2013, comprising around 31% and number is expected to grow to more than 23.6 million by 2030.
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priya6007-blog · 6 years
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Polylactic Acid Market - Opportunity Analysis and Forecasts to 2023
Global Polylactic Acid Market 2018 to 2023 focus on business Intelligence for revenue-generating processes, market research future illustrated some of the typical ways that is used to improve key revenue generation processes. Fundamentally, Polylactic Acid market analysis, new technology, scope, stake, progress, trends and opportunities are about using detailed and specific business information about client. Global Polylactic Acid Market research report spread across 138 Pages consist 35 Tables and 12 Figures  also include Top 10 Global key players that sharing latest types, technology, application by 2023.
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Polylactic Acid Market- Top 10 Global key Players & Their Strategy
Some of the prominent players operating in the Global Polylactic Acid Market are
BASF SE (Germany),
The DOW Chemical Company (U.S.),
Corbion (the Netherlands),
TEIJIN LIMITED. (Japan),
NatureWorks LLC (U.S.),
Synbra Technology bv (the Netherlands),
Galactic (Belgium),
Sulzer Ltd (Switzerland),
Hitachi, Ltd. (Japan),
Musashino Chemical Laboratory, Ltd. (Japan), and others.
Polylactic acid is a type of thermoplastic polyester obtained from wide variety of renewable feedstock such as wheat, corn, sugarcane, starch, and tapioca roots. PLA is made through two different processes namely condensation and polymerization. It is biodegradable as well as biocompatible in nature. PLA is a thermoplastic material and find its utilization in numerous application such as automotive, packaging, textile, electrical & electronics, consumer goods, and others.
Target Audience
Polylactic Acid Manufacturers
Traders and Distributors of Polylactic Acid
Production Process Industries
Potential Investors
Raw Material Suppliers
Nationalized Laboratory
For Technical and Professional Details Book Complete Polylactic Acid Market Report at https://www.marketresearchfuture.com/reports/polylactic-acid-market-4557
Polylactic Acid Market – Competitive Analysis
Stringent regulations implemented by various government bodies regarding the use of non-biodegradable plastic is estimated to propel the growth of the market. Moreover, depleting oil reserves coupled with increasing awareness regarding the benefits offer by the PLA is expected to drive the market growth. However, high cost associated with the production of PLA as compared to conventional plastics is anticipated to hamper the growth of the market during the review period.
Polylactic Acid Market – Segmentation Analysis
The Global Polylactic Acid Market is categorized on the basis of type, application, and region. On the basis of type, the market is classified into PLLA (Poly-L-lactic Acid), PDLA (Poly-D-lactic Acid), PDLLA (Poly-DL-lactic Acid). On the basis of application, the market is segmented into automotive, textile, packaging, consumer goods, electrical & electronics, and others. On the basis of regions, the market is categorized into Asia Pacific, Europe, Latin America, North America, and the Middle East & Africa.
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neulookmedspa · 7 years
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What is Sculptra?
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If you are over the age of 45, Sculptra is definitely a treatment that will be recommended for you by Gita Izadi, NP here at Neu Look Med Spa. But it can be confusing to understand what this product really is and what it can do. According to Skintour.com “Sculptra is an injectable liquid used to add volume to areas of the face to create a soft, natural, more youthful recontouring of the face. It builds your own collagen while it gradually disappears. When done well, it doesn’t have that “over stuffed” look that is all too common with other injectables”.
Sculptra Treatment
It is most commonly used to add volume to hollow cheeks, add definition to the jawline, and smooth nasal labial folds. It also can be used to get rid of wrinkles on the chest, knees, and elbows. But what makes this injectable unique? Sculptra (generic name is “poly-L-lactic acid” or PLLA) is a synthetic of lactic acid. Lactic acid is made in our muscles after exercise. Polylactic acid is lactic acid molecules stuck together in strings (a polymer). It is made in a laboratory and contains no animal products and no human DNA. It very gradually disappears by the action of your own cell enzymes” states Skintour.com. Many patients want a very gradual change when getting injectable treatments, and Sculptra is perfect for them. On average 3 treatments of 1-2 vials are needed about 5-10 weeks apart for the initial correction of volume loss. After that, one treatment per year will maintain the results. Sculptra lasts about 2 years verses many injectables that only last 6-12 months. Another treatment that Neu Look Med Spa offers is Buttock Augmentation with Sculptra. Its a great non surgical way to lift and contour your bum. Due to the area being larger, most patients will need at least 10-15 Vials in the first treatment and may need more depending on the look they want to achieve. But again this procedure can last for 2 years, which makes it a smart investment. Gita Izadi welcomes you to come in for a complimentary consultation to see if this treatment is right for you! Read the full article
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