#kwangcheol

[tarosucheon]

How To Become A Dragon As Tumblr Text Posts Pt. 1

[auro-cyanide]

Dragons! Some of whom are better at pretending to be human than others. (Actually only one is a real dragon)

[bpod-bpod]

Shoot Out

Bacteria often use sophisticated weaponry to pump human cells full of toxins. Legionella pneumophila (among other bacterial invaders) use this ‘Type IV secretion system’ to inject their hosts with around 300 molecules per 'shot'. This 3D computer model pieces together clues from electron cryotomography – examining the molecular mechanics in detail – followed by fluorescence microscopy to watch how they assemble and move. With its artificially-coloured red 'barrel' imbedded in a host cell, chambers around the outside of the tiny protein machine help to trigger the release of toxins. Knowing more about how all these mechanisms work together, scientists are developing new antibiotics to specifically disarm these bacterial 'guns' in the fight against Legionnaire’s disease, whooping cough and certain types of cancer.

Written by John Ankers

Video from work by Debnath Ghosal and Kwangcheol C. Jeong, and colleagues

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, and Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA

Video copyright held by Nature Publishing Group 2019; reproduced with permission

Published in Nature Microbiology, April 2019

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[thatisprettysmart]

Shoot Out

Bacteria often use sophisticated weaponry to pump human cells full of toxins. Legionella pneumophila (among other bacterial invaders) use this ‘Type IV secretion system’ to inject their hosts with around 300 molecules per 'shot'. This 3D computer model pieces together clues from electron cryotomography – examining the molecular mechanics in detail – followed by fluorescence microscopy to watch how they assemble and move. With its artificially-coloured red 'barrel' imbedded in a host cell, chambers around the outside of the tiny protein machine help to trigger the release of toxins. Knowing more about how all these mechanisms work together, scientists are developing new antibiotics to specifically disarm these bacterial 'guns' in the fight against Legionnaire’s disease, whooping cough and certain types of cancer.

Video from work by Debnath Ghosal and Kwangcheol C. Jeong, and colleagues

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, and Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, USA

Image copyright held by Nature Publishing Group 2019; reproduced with permission

Published in Nature Microbiology, April 2019

from BPoD - Biomedical Picture of the Day http://bit.ly/2N97faH

[zeaships-blog]

switch - kwangcheol

He always loved the way he danced. The way he appeared on stage, talked his face off, smiled at the camera. He loved how he admitted he had plastic surgery and lived with it. He loved the way he sang and didn't care if people hated it - it was obvious he wasn't a lead singer so why should people judge him on his singing ability when he was really just having fun? He loved it when he made fun of the other members constantly on shows. He was mad at him for calling him one of the unimportant members, but soon forgave him, too in love with his smile to let him pout at him for too long. He loved the way he spoke, especially, with such confidence that lacked in a lot of the members of their nine-member group.