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spacenutspod · 2 years ago

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After more than six months in space, four people are set to splashdown in the waters near Florida. The SpaceX Crew-6 mission, which launched on March 2 and docked with the International Space Station (ISS) the following day, will undock on Sept. 3 at 7:05 EDT (11:05 UTC). Recovery vessels are ready to retrieve the crew and their capsule, Crew Dragon Endeavour (C206), the Atlantic Ocean with the help of support vessel Megan in the early morning hours of Sept. 4. The four people returning to Earth, who were members of both Expedition 68 and 69 aboard the ISS, include Commander Stephen Bowen, Pilot Warren “Woody” Hoburg, both from NASA, Russian cosmonaut Andre Fedyaev, and Sultan AlNeyadi, the first long-duration crew member from the United Arab Emirates and only the second Emirati to fly in space. The four crewmembers of Crew-6 in their SpaceX suits aboard the ISS. (Credit: NASA) Undocking Crew Dragon Endeavour initially docked to the zenith port of the Harmony node of the ISS back in March. However, it was moved to the forward docking port of the same module in May to allow an incoming Cargo Dragon capsule to be closer to the station’s robotic arm, Canadarm2. It is from this forward port where Endeavour‘s onboard computers will autonomously back the capsule away from the orbiting laboratory. Dragon uses its built-in Draco thrusters over the course of two separate burns, known as burn zero and burn one, to maneuver outside of an area known as the “Keep-Out Sphere.” This imaginary circle, which extends 200 meters around the ISS, officially denotes when NASA and other ISS partner nations are involved with the mission. Once it leaves that sphere, mission control in Houston will only monitor the progress of reentry, while all aspects of control switch over to SpaceX. Crew Dragon Endeavour undocks from the ISS during the Crew-2 mission. (Credit: NASA/SpaceX) This is followed approximately one hour later by burn two, a longer burn that helps place the capsule in a lower orbit below and away from the ISS. SpaceX and NASA have seven splashdown sites with four located in the Gulf of Mexico and three in the Atlantic Ocean. The primary and secondary landing sites are typically selected two weeks in advance. Teams actively monitored Hurricane Idalia as it came through the Gulf, making landfall on Florida’s “big bend” region on Aug. 30, before proceeding northeast and into the Atlantic. Splashdown of this mission was initially scheduled for Sept. 3, however, NASA delayed it due to weather. It is unclear if the weather delay was a direct result of the hurricane. The seven possible splashdown locations for Crew-6. (Credit: NASA) See AlsoCrew-6 UpdatesNSF StoreL2 SpaceX SectionClick here to Join L2 SpaceX crew recovery ship Shannon was docked in Tampa along the west coast of Florida both in anticipation of the hurricane and for the crew splashdown. The second recovery vessel, Megan, was relocated to Port Everglades to ride out the storm before moving to its splashdown location near [xxx]. Megan, named after astronaut Megan McArthur, and Shannon, named after astronaut Shannon Walker, have been used on other Crew and Cargo Dragon missions to retrieve the spacecraft and crew members. Both ships are equipped with a helipad for astronauts to be transported to shore shortly after splashdown, a medical facility for observing and assessing astronauts’ conditions, and radar to track the spacecraft. The back of the boats also contains a lift. It attaches to special points on the capsule prepared by a fast response team that will take a smaller boat out and jump onto the freshly returned capsule. Once hooked up, it is lifted onto a “donut” stand and retracted underneath a covering on the ship. A Dragon capsule returns to Port Canaveral onboard one of SpaceX’s recovery ships. (Credit: Sawyer Rosenstein for NSF) The weather requirements for Crew Dragon splashdowns are as follows: no lightning within 10 miles, waves with no greater than a seven-degree slope, wind speed no greater than 12 miles per hour, less than a 25 percent chance of rain, and at least one-half mile visibility in the daytime or one mile at night. Entry Approximately one hour prior to splashdown, Endeavour will jettison its unpressurized segment known as the “trunk”, which will reveal Dragon’s tiled heat shield. This is followed shortly after by a deorbit burn, slowing the spacecraft down just enough that it will re-enter Earth’s atmosphere, which will then be used to help slow the craft down dramatically. The forward thrusters around the docking ring are used for this burn. Following completion of this burn, the nose cone closes and locks. This protects the just-used thrusters and docking ring in addition to other communication and rendezvous equipment which is no longer needed. Splashdown As plasma builds around the capsule, mission controllers will lose contact with the crew for a brief time known as a loss of signal, sometimes referred to as LOS. The SpaceX Crew Dragon Freedom returns to Earth following the Crew-4 mission. (Credit: NASA/Bill Ingalls) Once Endeavour has detected that it is at a certain altitude and velocity, it deploys its two drogue parachutes and slows down to around 560 kilometers per hour (350 miles per hour). The parachutes partially deploy at first before fully inflating in a process known as reefing. Reefing allows parachutes to open in a slower and more controlled manner to avoid higher loads on the vehicle and crew during descent. Shortly after full drogue inflation, the drogue parachutes are cut and the main parachutes are deployed. The four main parachutes also reef to ease the loads on the capsule and crew. The main parachutes slow Dragon down to around 24 kilometers per hour (15 miles per hour) for splashdown. Crew-6 Mission The crew contributed to hundreds of different science experiments and technology demonstrations according to NASA. These included human health experiments, such as BFF-Meniscus-2, which printed knee tissue in microgravity as an experiment in bioprinting. During a spacewalk, the crew helped install more of the Station’s new ISS Roll-Out Solar Arrays (iROSA). Once all are installed, these are expected to enable a 30% increase in power for operations and scientific investigations on the orbiting lab. The crew also conducted science involving our own planet, photographing and documenting the planet along with connecting with and talking to students across the globe from space. This mission marks SpaceX’s sixth operational crew mission to the ISS under NASA’s Commercial Crew Program. (Lead image: Crew Dragon Endeavour docks to the ISS during the Crew-6 mission. Credit: SpaceX) The post SpaceX crew to return to Earth after six-month ISS Stay appeared first on NASASpaceFlight.com.

#space #astronomy #news #science

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sere22world · 4 years ago

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Soft Serve 101: Significant Features, Benefits And Ways To Save

If you are considering buying a soft serve ice cream machine for the restaurant, dinner, buffet or convenience shop, there are a couple of crucial things to make note of.

Soft serve is a kind of ice cream or frozen dessert, like yoghurt, custard, sorbet, which haven't really been hard frozen but instead is produced with the addition of air to the ice cream mixture, increasing its volume by up to 45 percent. The combination of greater temperature (approximately 18º F) and more air gives the ice cream a creamier consistency and makes it simple to dispense.

Energy Efficiency

Soft serve ice cream machines operate effectively to freeze and include air (quantity ) to specific liquid soft serve ice cream mixtures. Machines run in a temperature around 18 degrees Fahrenheit, keeping the ice cream not just frozen but at appropriate storage temperatures. Because of this, these machines need to run both day and night to protect against any changes in consistency or health code violations.

Various Sizes

Smaller service operations which need to being offering soft serve ice cream often own small counter machines, allowing a worker to refill and create new batches as required. Buffet and sundae pubs are often self-service, and these operations typically purchase large secondhand machines to keep a higher volumes of ice cream. Bigger machines, but cost more to buy, operate and maintain as well.

Features & Options

There are a variety of features and options that are analyzed when exploring soft-serve ice cream machines:

Soft serve Machines come with either a gravity-feed or even a pressurized feed. Pressurized machines utilize pumps to supply the freezing cylinder.

The freezing cylinder as well as the dasher bar that mixes the product are at the heart of the soft-serve ice cream machine's functionality. Look closely at your machine's design and how these two features work together.

Newer machines can come with optional touch-pad LED displays to place warmth and consistency of the ice cream. Once installed, the system automatically adjusts to save time when switching mixtures.

Some machines comprise a safety mechanism to prevent compressor burnout. Some components shut down if no one responds to the awake within a certain period of time, along with others yet to shoot hot refrigerant gas from the condenser into the barrel to keep it from freezing solidly when the mix is too low.

General Specs

Soft Serve Ice Cream portions with fruit

Programs:

Soft serve ice cream and desserts may be served straight up in a cone or bowl, or as a foundation for desserts like banana spilts, milkshakes and rootbeer floats.

Size:

Machines can be found in counter-top and floor versions. Even footprints of large machines are relatively compact, using high volume twin barrel machines being about 26" wide and 36" deep.

Ability:

As with several different types of equipment, one important point to consider when selecting a soft serve machine will be capacity. Machine capacity is measured in quantity, either gallons per hour or two servings per minute. Reduced volume is usually 2-3 serving each second, medium is 4-5 parts and high quantity is 7 servings.

Counter Top 7 Quart 4oz Serving 2-3 parts

Counter Top 20 Quart 4oz Serving 3-7 servings

Characteristics:

Soft serve machines are self contained unit that will store blend, then churn and freeze it in ice cream, and dispense it. Retrieval time is therefore important. If you take a moderate or higher volume machine for manufacturing, the machine needs to have the ability to freeze additional product to replenish what's being dispensed.

Pressurized machines pumps to supply the freezing cylinder.

Many versions have signature pad LED displays to place the warmth and/or consistency of the final product. Once installed, the machines automatically adjust for whatever mix is utilized.

Other controls include a low-mix light which indicates when it is time to replenish the mixture hopper. If the barrel isn't full, the mix can freeze strong, preventing the dasher pub from turning. A suspended cylinder can split the bladesand bend the dasher bar, or burn the breaker.

Many models have a security mechanism to stop compressor burnout. On some, the compressor automatically shuts down if you do not reply to the low-mix alarm in just three minutes. Other models take hot refrigerant gas from the condenser to the barrel to keep it from freezing solidly when the blend amount is too low.

Energy Supply:

To ensure widespread compatibility with most foodservice situations, most smaller units operate on single phase 115 volts and larger units 208-230 volts.

Temperature Range:

A temperature-controlled machine allows the ice cream to distribute as it reaches a certain temperature, usually 18º F to 19º F. Many machines have a"night" or"sleep" switch that lets you conserve energy where permitted by local health programs. In this mode, the ice cream is allowed to thaw and be stored at 38º F till you're ready to restart the machine.

Construction:

The center of all soft-serve machines is that the barrel where the ice cream is generated. Each manufacturer uses its own layout for both the freezing cylinder itself as well as the beater or dasher pub that mixes and pushes the ice cream into the dispensing head.

There are two varieties of dasher bar designs: low and higher displacement. But some manufacturers use them in soft-serve machines to enhance the machine's efficiency.

Depending on the type of product that you need to function as dasher bar engine speed should be considered. If you plan to use a product with greater butterfat a higher rpm motor can churn the mixture a lot in the barrel.

Blades connected to the dasher bar scratch mixture off the walls of the cylinder as it stinks. Most are created with some type of plastic, nevertheless they really do wear, and when worn blades depart frozen mixture on the walls of the barrel, the machine will function less and less efficiently.

To continue to keep blades sharp some manufacturers have"self-sharpening" blades. Others attach blades to the dasher using a calibrated spring. Blades normally require replacing every six months or so based on quantity. To signify when a blade is ready to be replaced some have use lines to reveal employees when to change them. Others are designed to prevent workers from installing them improperly when they are washed or changed.

The ability of any machine ought to match the type of production you need for your own operation. Dasher bar engines, by way of instance, include 1/2 hp and higher. Compressor motors begin at 1 HP on small machines, while most machines have 2 HP compressors to swiftly pull product from 38º F to 18º F, and also dispense cone after cone. Many versions currently use Scroll compressors, which can be more energy-efficient than conventional compressor motors.

Though these powerful components are in operation the system will throw off a lot of heat. Since most soft-serve machines are behind the counter or out in serving areas, that heat can affect both workers and clients in addition to how challenging the machine itself functions.

You have a few choices on the best way best to deal with this warmth.

Air-cooled units provide positioning flexibility as they don't expect a water hook-up, only an electrical outlet. Allow about 3" of clearance around the entire machine, and intend to provide air conditioning to dissipate heat from the compressor, dasher motor and condenser.

Water-cooled machines really are a good option if you purchase a model that has a self indulgent recirculating system so that you're not paying for water to go down the drain. As an alternative, you may use the waste heat from the water which cools the soft-serve system to warm water in the rest of your operation.

Soft serve machines using a remote condenser, generally roof-mounted, will dissipate some of the heat outside. However, you must have a relatively short run to the roofing to the refrigerant lines.

Care:

Before buying a soft serve machines, check with your regional inspector or health department to be aware of the rules for your area.

Several methods have been developed to ease the cleaning procedure, including washout kits, which can be essentially faucet hookups for the top of the machine which enables you to turn on the water directly into the hopper. Most providers also provide parts trays that provide employees molded spaces to store components since they disassemble and clean them. This helps employees monitor parts to properly compress the system.

Other versions have an auto-cleaning manner that flushes and cleans the machine innards at the push of a button. These models need disassembly occasionally to wash and sanitize parts which might not get a thorough cleaning. Auto-cleaning can save employees a lot of time, and companies labour price, if it considerably reduces the amount of times the machine needs to be eliminated for cleaning.

Certifications:

Components must be NSF listed under standard No.7, and UL Safety and UL Sanitation listed.

Have questions on purchasing a soft serve machine? Contact Hommy ice cream machine manufacturer!

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dorcasrempel · 6 years ago

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High-precision technique stores cellular “memory” in DNA

Using a technique that can precisely edit DNA bases, MIT researchers have created a way to store complex “memories” in the DNA of living cells, including human cells.

The new system, known as DOMINO, can be used to record the intensity, duration, sequence, and timing of many events in the life of a cell, such as exposures to certain chemicals. This memory-storage capacity can act as the foundation of complex circuits in which one event, or series of events, triggers another event, such as the production of a fluorescent protein.

“This platform gives us a way to encode memory and logic operations in cells in a scalable fashion,” says Fahim Farzadfard, a Schmidt Science Postdoctoral Fellow at MIT and the lead author of the paper. “Similar to silicon-based computers, in order to create complex forms of logic and computation, we need to have access to vast amounts of memory.”

Applications for these types of complex memory circuits include tracking the changes that occur from generation to generation as cells differentiate, or creating sensors that could detect, and possibly treat, diseased cells.

Timothy Lu, an MIT associate professor of electrical engineering and computer science and of biological engineering, is the senior author of the study, which appears in the Aug. 22 issue of Molecular Cell. Other authors of the paper include Harvard University graduate student Nava Gharaei, former MIT researcher Yasutomi Higashikuni, MIT graduate student Giyoung Jung, and MIT postdoc Jicong Cao.

Written in DNA

Several years ago, Lu’s lab developed a memory storage system based on enzymes called DNA recombinases, which can “flip” segments of DNA when a specific event occurs. However, this approach is limited in scale: It can only record one or two events, because the DNA sequences that have to be flipped are very large, and each requires a different recombinase.

Lu and Farzadfard then developed a more targeted approach in which they could insert new DNA sequences into predetermined locations in the genome, but that approach only worked in bacterial cells. In 2016, they developed a memory storage system based on CRISPR, a genome-editing system that consists of a DNA-cutting enzyme called Cas9 and a short RNA strand that guides the enzyme to a specific area of the genome.

This CRISPR-based process allowed the researchers to insert mutations at specific DNA locations, but it relied on the cell’s own DNA-repair machinery to generate mutations after Cas9 cut the DNA. This meant that the mutational outcomes were not always predictable, thus limiting the amount of information that could be stored.

The new DOMINO system uses a variant of the CRISPR-Cas9 enzyme that makes more well-defined mutations because it directly modifies and stores bits of information in DNA bases instead of cutting DNA and waiting for cells to repair the damage. The researchers showed that they could get this system to work accurately in both human and bacterial cells.

“This paper tries to overcome all the limitations of the previous ones,” Lu says. “It gets us much closer to the ultimate vision, which is to have robust, highly scalable, and defined memory systems, similar to how a hard drive would work.”

To achieve this higher level of precision, the researchers attached a version of Cas9 to a recently developed “base editor” enzyme, which can convert the nucleotide cytosine to thymine without breaking the double-stranded DNA.

Guide RNA strands, which direct the base editor where to make this switch, are produced only when certain inputs are present in the cell. When one of the target inputs is present, the guide RNA leads the base editor either to a stretch of DNA that the researchers added to the cell’s nucleus, or to genes found in the cell’s own genome, depending on the application. Measuring the resulting cytosine to thymine mutations allows the researchers to determine what the cell has been exposed to.

“You can design the system so that each combination of the inputs gives you a unique mutational signature, and from that signature you can tell which combination of the inputs has been present,” Farzadfard says.

Complex calculations

The researchers used DOMINO to create circuits that perform logic calculations, including AND and OR gates, which can detect the presence of multiple inputs. They also created circuits that can record cascades of events that occur in a certain order, similar to an array of dominos falling.

“This is very innovative work that enables recording and retrieving cellular information using DNA. The ability to perform sequential or logic computation and associative learning is particularly impressive,” says Wilson Wong, an associate professor of biomedical engineering at Boston University, who was not involved in the research. “This work highlights novel genetic circuits that can be achieved with CRISPR/Cas.”

Most previous versions of cellular memory storage have required stored memories to be read by sequencing the DNA. However, that process destroys the cells, so no further experiments can be done on them. In this study, the researchers designed their circuits so that the final output would activate the gene for green fluorescent protein (GFP). By measuring the level of fluorescence, the researchers could estimate how many mutations had accumulated, without killing the cells. The technology could potentially be used to create mouse immune cells that produce GFP when certain signaling molecules are activated, which researchers could analyze by periodically taking blood samples from the mice.

Another possible application is designing circuits that can detect gene activity linked to cancer, the researchers say. Such circuits could also be programmed to turn on genes that produce cancer-fighting molecules, allowing the system to both detect and treat the disease. “Those are applications that may be further away from real-world use but are certainly enabled by this type of technology,” Lu says.

The research was funded by the National Institutes of Health, the Office of Naval Research, the National Science Foundation, the Defense Advanced Research Projects Agency, the MIT Center for Microbiome Informatics and Therapeutics, and the NSF Expeditions in Computing Program Award.

High-precision technique stores cellular “memory” in DNA syndicated from https://osmowaterfilters.blogspot.com/

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adanzampa-blog · 7 years ago

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EML to NSF Conversion - EML to IBM Lotus Notes Converter

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worldupdatereviews2017-blog · 8 years ago

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The way to prevent apps from amassing your e-mail statistics

New Post has been published on https://worldupdatereviews.com/the-way-to-prevent-apps-from-amassing-your-e-mail-statistics/

The way to prevent apps from amassing your e-mail statistics

On Sunday, the NY Times reported that analytics employer Slice cold facts about Lyft riders gleaned from their electronic mail receipts to Uber. Slice owns Unroll.Me, a provider for organizing and deleting subscription emails out of your inbox.

Unroll.Me customers grant the provider permission to get admission to emails and different personal information. The service then takes records about their purchases, anonymizes it, and sells it to other groups. People had been amazed and outraged to discover this changed into how Unroll.I used their facts. The service becomes based in 2011, and bought by means of Slice in 2014.

On Monday, Unroll.Me co-founder and CEO Jojo Hedaya replied, pronouncing he is “heartbroken” Humans “had been disenchanted to study how we monetize our loose service.”

The non-apology further fanned the flames. The business enterprise stated it will make its regulations approximately facts series cleaner going forward. (It became within the carrier’s privacy coverage, amidst all of the other nice print that few consumers take the time to examine.) The Significance of Capturing Purchaser e-mail data Client e-mail statistics is one of the most valuable sources available to manufacturers within the advertising subject. accumulating and being on top of things of a Consumer database no longer only affords your business enterprise with an immediate link to your most dependable consumers, it permits your brand to communicate in a manner this is non-public and rather powerful. e-mail verbal exchange together with your customers can take much paperwork – whether you clearly want to preserve your customers up to date on what’s occurring on your company or whether or not you operate their records to create perfectly customized promotional campaigns – the fact remains that your business enterprise database is the gas that drives the maximum powerful engine in digital marketing: email.

Why email continues to be the fine

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