#water filtration system manufacturers in Hyderabad

[sewagetreatmentplant]

Sewage Treatment Plant Manufacturers In Hyderabad

The sewage treatment plant is one of the feasible and cost-effective ways to treat reusable water. Our high-quality biological sewage treatment plant effectively removes the varied contaminants from the sewage water. The sewage treatment plant is manufactured from the premium quality raw materials that add efficiency. Rugged structure, easy installation and excellent performance are the salient features of our sewage treatment plant that makes it perfect for gardening or toilet flushing purposes. We have firmly positioned ourselves as one of the major sewage treatment plant suppliers in India.

There are different Products in Sewage Treatment Plant Those are,

1. pp wound filter cartridges.

2. mini ro water treatment plant.

3. effluent water treatment plant.

4.demineralization water treatment plant.

5. water softening plant.

6. multimedia filtration system.

[halar-antistatic-coating]

Advanced Expertise Technology Leaders in Fluoropolymer Coating, Lining, and Pharma Machinery

Advanced Expertise Technology Pvt. Ltd. (ADVETPL) is a leading manufacturer and supplier of pharmaceutical machinery and Fluoropolymer Coating. We are the leaders in designing and manufacturing machinery related to the supply of Fluoropolymer Lining and coating which is utilized in the manufacturing of Active Pharmaceutical Ingredient, Medications, Food and food products, synthesized chemicals, fine chemicals, petrochemical and for treatment of surface and ore.

We provide different types of coating like HALAR, PVDF, ETFE, PFA,PP and PTFE. These coatings prepare the material against factors like abrasion and corrosion. Our coatings can be applied on various materials of processing appliances such as Tanks, Receivers, Agitated Nutshe filters, Centrifuge Machines, Agitators, Heat exchangers, Strainers, Rotary Vacuum cone dryers, Valves, etc.

Our team constantly works to deliver the best quality products and services. We believe that accuracy and quality are the most important factors that are needed to be delivered to our customers. Our clients are spread around the world, ranging from small-scale industries to MNCs.

We are the sole competitors in the market, who provide a comprehensive solution to customer queries, with our committed and skilled service crew being available on sites in Vizag, Chennai, Mumbai, Gujarat, and Hyderabad. We also provide services to existing machinery recoating, lining, and centrifuge.

Using advanced technology, high-end tools, exceptional quality management system, we work towards providing our customers with products of the highest quality which give optimum performance with cost-effectiveness.

The ultimate goal of our company is complete profitability and satisfaction for our customers.

Workshop and Plan Details

The Fluoropolymer coating industry workshop of our company is one of the largest in India with its area spread across 28,000 Sq.ft.

We offer Electro conductive and Anti-static coating for HALAR, PFA, and ETFE. Our processes are designed in a manner that offers no harm to people and plants, and our coating is also compatible with food.

Our groups of companies are spread out all over India, they are India glass-lined equipment, Porima Technology Pvt.Ltd., Synovatic India Machinery Pvt Ltd., Leborn Technomach, and last but not the least Advanced Expertise Controlling System. Together we work to meet the International standards and design, market, and manufacture products of premium quality with high performance to our clients.

Our products come in a wide variety.

Filter Equipment - Filters are used to separate the solid molecules from liquid or gas. Either the filtrate or the solid particles removed may be the desired product. We are a leading supplier of different varieties of a filter.

Our products include, Centrifuge filters used in pharmaceutical, fine chemical, dye intermediates, and chemical industry. Sparkler filters are used in biotech, bulk drugs, food distilleries, and API industries, a candle filter is used where polishing and low moisture cake filtration is required. Pressure Nutsche filter these handle variety of flow rated and work on the principle of pressure and volume, a Cartridge filter is used in beverage, alcohol, solvent, chemical and cosmetics industry. Basket filter is used for separating contamination from fluids

Drying Equipment - Removes moisture from the material, making it safe for storage and processing. We provide a variety of drying equipment, Vacuum Tray dryers are used in the herbal, chemical, food products, and healthcare industries. Air tray dryers are used in the automobile and chemical industry, and Rotary cone vacuum dryer food and pharmacy industry.

Heavy Engineering-We design and build large units of machinery according to regulated codes and standards. Our product range includes receivers, heat exchangers, pressure vessels, and reactor storage tanks.

We provide different types of Fluoropolymer Coating and Lining Service

The most notable and highly acclaimed work of our company is Fluoropolymer Coating. These coatings are used diligently in different environments. The most prominent attribute of these coating are, that they are heat-proof, non-stick , and resistant to corrosion and chemicals.

Few listed advantages of PTFE, HALAR, ETFE, and PFA coating and lining services.

It can be cleaned effortlessly.

Does not require care and keep-up.

Safe to operate on hazardous substances.

We are a leading brand in India for Fluoropolymer Coating and Lining. Our coating products , PVDF, HALAR (ECTFE), ETFE, PP, and PFA are used in machinery for Pesticide, API, Cryogenics Corrosion, BULK Drug, Fluorine, and Bromine Handling, Pharmaceutical, Fine Chemical, Chemical, Inorganic Chemical, Surface treatments, Petrochemical, Powder Industry, Paper Industry, Bio Diesel Industry, etc.

HALAR Antistatic Coating (ECTFE Coating)

Industries in which resistance and protection from corrosion and high temperature are required Ethylene chlorotrifluoroethylene coating is applied. ECTFE coating provides high resistance from chemicals and elevated temperature conditions. These are most suited for appliances with a full vacuum.

PFA Coating (Perfluoroalkoxy Alkane Coating)

Perfluoroalkoxy Alkane coating provides extensive protection in adverse environments involving chemicals at high temperatures, from inorganic oxidizers and bases, strong mineral acids, inorganic and organic compounds, mechanical and thermal stress. PFA coatings have similar characteristics to PTFE. These coatings are applied on stainless steel and carbon steel varying temperature surrounding.

ETFE and PTFE Coating

Ethylene tetrafluoroethylene coating is highly robust and resistant to chafing. It provides high corrosion resistance, protection from radiation, and wear over a varied range of temperatures, also because of its high melting point, it prevents the emission of harmful gases when burnt. ETFE coating is known for its adaptability and rare features. This coating is used in the petrochemical and chemical industries.

PTFE coating is a thin layer of film and very durable. It is generally known as Teflon. It is highly resistant to water and can work in extreme weather conditions. Polytetrafluoroethylene coating is commonly used to apply Non-stick coating for cookware and pans. Teflon Coating is non-reactive, chafing resistant, thus it is used in lining pipes and containers where corrosive and reactive chemicals are used.

PP Coating (Polypropylene Coating)

Polypropylene coating is used for storing hydrochloric, hydrofluoric, and sulfuric acids, caustics, corrosives, etc. It belongs to the group of partially crystallized and non-polar. Polyolefins. It is a thermoplastic polymer also known as a polyprotein.

PVDF Coating (Polyvinylidene Fluoride Coating)

Polyvinylidene Fluoride coating is used in places that require robustness, purity, resistance to acids, solvents, and bases. These coatings can melt easily due to their low melting point. It is light in weight and cost-effective in comparison to other fluoropolymers. PVDF coating is widely used in the semiconductor, defense, and medical industries. It is used in the manufacturing of appliances like pipes, valves, tubes, sensors, etc.

Peek Coating

Fluoropolymer contains molecules of fluorine and carbon. Peek coating demand is high in industrial coatings because they provide low friction, corrosion, chemical, water, and abrasion resistance.

Our company goal is to manufacture reliable, durable, and cost-effective products. We try to reach the highest standard while manufacturing our products to satisfy our customer base. We work towards the overall profitability of our clients, and we constantly grow ourselves to work with changing and emerging technologies to fulfill our customer needs.

[smartroservice]

Need For The Water Purification Technology And Their Advancements : Aquaguard Service gurgaon

Increasing demand and lower availability of water is that the common problem everywhere the planet as many parts of the world don't have the water even for drinking purposes. As we all know that just one percent of earth’s water is prepared for drinking because the remainder of the rain falls within the category of saltwater, which is sweet for nothing without proper cleaning and softening. If you're living within the city that features a n adequate amount of water but has a problem in its quality, then the RO water purification system is that the only option which will be proved to be beneficial during a low effort.

Lowering water quality raises the water purification business at another level and continuously growing. you've got chosen any of the available options among all which suits you the simplest after having a water quality check at your home. Request a free water quality on any of the registered water purifier manufacturers which are within the business for long years. this provides you a rough idea about what you've got to shop for and why it's needed. They also suggest the simplest suitable water purification system among all the available models. Some popular water purification technologies are reverse osmosis, ultraviolet, TDS, and water softeners.

Why we'd like Water Quality Check Before Purchasing:

Water Purification Technology Plant

After browsing all the available models, you would like to select the simplest brand from the present market. As we all know, leading water purifier maker brands like Aquaguard. This company has countless models specialized for all regions of water consistent with their complexity. Water manufacturing companies also are making series filtration technologies for complete removal of undesired components like microorganisms, soils, chemicals, and excess salts. Series filters like RO for pollutant removal, UV for microbe’s degradation, TDS controller for excess minerals removal, and softener for creating it sweet and pleasant.

DIY Detox Water Drinks for Weight Loss and Cleansing

Choosing a water purifier for you domestic purpose offers you numerous benefits like complete protection from deadly waterborne diseases, low tide wastage, minimum effort, and save tons of cash . people that prefer drinking water over RO purified water. they're making an enormous mistake because they are doing not follow any water purification laws and standards. it's to not believe blindly on the packaged water because it could also be loosely filtered or packaged by unprofessional workers. Their water jars are always dirty, and wrong gestured that permits all the germs to grow in it.

Ancient Technology VS Modern Technologies:

There are several water purification technologies utilized in old-time like boiling at 100 degrees Celsius, filtering with clean clothes, sand filtration, and lots of others by natural herbs. that point pollution isn't at this level where most of the water bodies are filled with human-made chemicals that's a results of development and urbanization. Human-made chemicals are hard to filter by these simple technologies because it demands more specific water purification technologies which will filter dissolved compounds during a single treatment cycle. Developed technologies are high yielding and time-saving techniques due to highly particular technologies.

As per the planet health organization report, half the world’s population is suffering from the water crisis. India is additionally facing an equivalent problem in many of the cities like Delhi, Mumbai, Hyderabad, Gurgaon, et al. . Always choose the leading brand of water purifier which will offer you one hundred pc pure and clean water during a single cycle. Water purifier models are available in electric and non-electric models also that you simply can choose as per your requirement.

Also Read: Best Infused Water Recipes to Relish Through The Summer Days

Causes Behind the need Of Water Purifier:

There are various reasons that are liable for the depletion of the water quality like cutting of trees, urbanization, factory establishment near the rivers, and improper disposal of water in natural water bodies. Manufacturing factories are employing a great quantity of unpolluted water within the ir cleansing and production purposes and vomit in the rivers. It makes water bodies good for nothing and makes aquatic life much harder. Leading human-made chemical usage depletes water quality and makes it unhealthy.

The demand for a contemporary water purification system is getting higher a day as manufacturing companies also are increasing. thanks to an uncountable number of local filter manufacturers, it's hard to seek out the authentic product and their spare parts. Local service providers are making cheap products to offer fierce competition to the worldwide manufacturers. you simply got to check the specified filter, required size of the cistern , technology, and annual plans offered by them. you'll also contact the Aquaguard RO service Gurgaon provider as they supply the trusted and excellent quality product.

Conclusion:

These are some things that are bound to be in your mind while buying a water purifier for any purpose. it's always found useful and saves tons of cash and time-wasting in checking out a water purifier.

[latestmarketresearch]

Get a Market Research Report on Water Purifier Market 2020

JUNE 12, 2020: India water purifier market

Water purifiers are no longer considered to be consumer durables limited to affluent households. Increasing awareness coupled with lower prices have increased the penetration of water purifiers across lower income groups and rural households in the country. Reverse osmosis (RO) technology embedded in modern water purifiers is the most popular category.

Water purifiers range from simple water filters to advanced purifiers using membrane technology for water filtration followed by disinfection with ultraviolet (UV) lamp filters. Water purification has evolved, from using clay to filter out the sediments, to advanced water purification technologies that use electricity and the internet.

To Request A Sample Copy Of This Report @:   https://www.radiantinsights.com/research/water-purifier-market-in-india-2018-2023/request-sample

Import of household type water filters by value has grown at a compound annual growth rate (CAGR) of ~15.2%, where in terms of volume, it has gone down at a CAGR of ~21.5% during FY 2014 to FY 2018 due to a reduction in customs duty. Bangladesh is the largest importer of water filters for homes both in terms of value and volume for FY 2017 and FY 2018, followed by Philippines, Indonesia and Sri Lanka among others.

Key growth factors

• Manufacturers are producing affordable water-purifying units in order to penetrate the market. The price of water purifiers range from INR 500 - INR 20,000. Low-cost purifiers are easy to maintain and the refilling/refurbishing cost is also not very high.

• India has the world's highest number of people who are without access to clean water. Moreover, challenges such as acute shortage, excessive salinity, and depleting underground water reserves plague the water distribution system. The proportionate levels of total dissolved solids (TDS), hardness, chlorides, and nitrates among others responsible for water contamination, have exceeded the permissible limits in certain parts of Mumbai, Delhi, Bangalore, Lucknow, Pune, Hyderabad, Kolkata and Chennai.

Threats and key players

• Water purifiers are considered to be a push product requiring considerable concept selling in rural markets, and penetration of water purifiers in rural India is also lower due to economic factors, poor sales and lack of distribution networks

• Eureka Forbes Limited, KENT RO Systems Limited, Blue Star Limited, Hindustan Unilever Limited and Tata Chemicals Limited are some of the major players operating in the Indian water purifier market

What is covered in the report?

1. Overview of the Indian water purifier market

2. Historical, current and forecasted market size data for the Indian water purifier market (2016 to 2023)

3. Qualitative analysis of the Indian water purifier market and its segments (by company- Eureka Forbes, Kent Ro, Livpure and others)

4. Trade analysis of the water purifier market in India

5. Qualitative analysis of the major drivers and challenges affecting the market

6. Analysis of the competitive landscape and profiles of major players operating in the market

7. Key recent developments associated with the water purifier market in India

Why buy?

1. Get a broad understanding of the water purifier market in India, the dynamics of the market and current state of the sector

2. Strategize marketing, market-entry, market expansion and other business plans by understanding the factors driving growth in the market

3. Be informed regarding the key developments in the water purifier market in India

4. Understand major competitors' business strategies and market dynamics and respond accordingly to benefit from the market

To Browse Full Research Report @: https://www.radiantinsights.com/research/water-purifier-market-in-india-2018-2023

Table of Contents

Chapter 1: Executive summary

Chapter 2: Socio-economic indicators

Chapter 3: Introduction

3.1. Water purifier market definition and structure

Chapter 4: Water purifier market - overview

4.1. Residential water purifier market size & growth forecast - value-wise

4.2. Porter’s five forces analysis

Chapter 5: Water purifier market - segmentation

5.1. Company-wise market share - percentage split

• Eureka Forbes

• Kent RO

• Livpure

• Others

5.2. Organized vs unorganized – percentage split

Chapter 6: Trade analysis

6.1. Export of home insecticides

• Value-wise

• Volume-wise

• Country-wise

6.2. Import of home insecticides

• Value-wise

• Volume-wise

• Country-wise

 Chapter 7: Key growth drivers of the market

Chapter 8: Key deterrents to the growth of the market

Chapter 9: Competitive landscape

9.1. Product benchmarking – Top five players

9.2. Blue Star Limited

• Corporate information

• Business description

• Products and services

• Key people

• Financial snapshot (total income, net profit/loss)

• Key ratios

• Business segments, geographical segments

9.3. Hindustan Unilever Limited

• Corporate information

• Business description

• Products and services

Continued………………

To See More Reports of This Category by Radiant Insights: https://latestmarkettrends.news.blog/

About Radiant Insights: Radiant Insights is a platform for companies looking to meet their market research and business intelligence requirements. It assist and facilitate organizations and individuals procure market research reports, helping them in the decision making process. The Organization has a comprehensive collection of reports, covering over 40 key industries and a host of micro markets. In addition to over extensive database of reports, experienced research coordinators also offer a host of ancillary services such as, research partnerships/ tie-ups and customized research solutions.

Media Contact: Company Name: Radiant Insights, Inc Contact Person: Michelle Thoras Email: sales@radiantinsights.com Phone: (415) 349-0054 Address: 201 Spear St #1100, Suite #3036 City: San Francisco State: California Country: United States

[hydromo]

Top Global Water Management Companies in India

Top Global Water Management Companies in India

Today, one out of nine individuals needs access to safe water. As per the reports, 900 million people are living without access to safe water and this clearly reveals that it is still one of the issues that should be taken care of. Water crisis is also a health crisis as access to safe water means an opportunity for improved health to fight diseases causing trouble. Water Treatment Companies play a vital role when it comes to the health of individuals. Usually, Water Treatment does not solely involve in the method of purifying water to make it drinkable but also involves in industry level processing of water to utilize it for varied Industries.

Water Treatment Includes purifying methods like Filtration, chemical treatments like Reverse Diffusion & Sedimentation that make the water the most essential Components for everything to neutralize the water quality.

So, let’s have a glance at top Water Treatment Co-operations that offer domestic as well as industry level water solutions in India.

GE Water

GE Water process and technology is part of the GE group founded in the year 1892 and focused to fulfill the requirement of drinking water for the people in India. The Company has 50 projects and 20 undertaking projects in India to develop the municipal water treatment, industrial water treatment, metal removal and also monitor the quality of drinking water. It’s providing comprehensive Solutions for all Water and Waste Water treatment, water recycling needs and customized solutions for customer’s Solutions with high potency and low operation prices.

Thermax India

The corporate company has over 40 years of contribution in the field of treating waste matter for a sustainable environment. The company has 19 international offices, 11 manufacturing units and 12 sales offices and provides water solutions that include water treatment, effluent treatment, desalination and much more. Thermax provides cost-effective raw water treatment solutions for the reduction of suspended solids in surface water.

VA Tech Wabag GMBH

The Organization VA Tech Wabag GMBH is an Indian multinational company with headquarters in Chennai, India established and commencing its pursuit in the year of 1996 offering its services such as municipal water treatment and industrial wastewater treatment facility in Metros like Delhi, Kolkata, Pune, Vadodara and also countries like Austria, Algeria, Tunisia, Romania, Turkey etc., and Substantially more. The company Founded in Breslau in 1924 which is a pure-play water technology company concentrated on Water Treatment for Metropolitan and Industrial clients and is recognized for its quality and divine service in the field of water treatment. This is an Association which offers Water treatment, Industrial water treatment, sea water desalination, wastewater treatment and sludge treatment services.

SIMENS water technologies

SIEMENS Water Treatment Company provides qualitative service in the field of Water Treatment and Sewage Treatment in India since the year of 1969. It mostly focuses and has its expertise in water treatment through electrification, automation and digitization techniques of water treatment as well as sewage treatment. Specializes in providing world-leading water treatment products, system and services for agricultural and industrial applications.

Volta’s Water Management and Treatment Limited

The company commences its pursuit in India in the year of 1977 as a joint endeavor with Ames Crosta Babcock, UK. The company provides wastewater treatment and sewage treatment for public water supply and few ventures for sustainable development in the environment. Voltas Water management is the Maker of full range water, wastewater and Sewage Water Treatment equipment’s utilizing strategies that are of top-notch standards.

Hindustan Dorr-Oliver Limited

Hindustan Dorr-Oliver Limited is the sole Indian based pioneer company providing water and wastewater treatment in India. It provides numerous products and services like design, building, operating, maintaining, upgrading and proper Management of Water and Wastewater Plants. It additionally provides desalination of sea water in order to provide drinking water in the areas of acute shortage of drinking water. Engaged in providing engineering and turnkey solutions & technologies across diverse business verticals such as Environmental, Paper & Pulp, Hydrocarbon Sector and more.

W.O.G. Technologies

W.O.G. Technology is the global water treatment or sewage Treatment Company operating from the USA, Thailand, Singapore, Pakistan, Portugal and other countries. The company provides sustainable and eco-friendly solutions for Wastewater Treatment withholding utmost expertise & skillful professionals and technocrats which help the company to provide the technology-based solutions to water and sewage treatment.

UEM Clean Solution

The UEM Clean Solution is a Global environmental service company providing safe drinking water since the year 1973. The company’s main focus is providing a genuine solution to wastewater treatment in addition to end-to-end services like the collection of wastewater, treatment of the wastewater, disposal by designing, construction, maintenance and operation of wastewater treatment plants. UEM Clean Solutions focuses on the areas of surface, ground, and sea Water Desalination and alternative water treatment services.

SFC Environmental Technologies Private Ltd.:

SFC Environmental Technologies Private Ltd. is equipped with most cutting edge machinery and technology towards water treatment with Numerous Advance techniques such as C-Tech a radar technology for treating of waste, C-MEM (micro/ultra filtration), C-FLOC, C-Filt, and C-RO (reverse osmosis) for the treatment of sewage and industrial waste. The company is operating in multiple countries as India, Egypt, Vietnam, China, Czech Republic, Austria and Poland. Due to its methods and scientific way of treating the waste, it has gained the preferences of most people. Usage of different contemporary technologies like C-MEM, C-FLOC, C-FILT and C-RO, water treatment is ensured with a noteworthy degree of quality.

ION Exchange India Ltd:

The company was an associate to Asian nation subsidiary of the Permutit Company UK who sold their holding to India and now, primarily it’s an Indian based company. The company is providing services like water treatment, water recycling, Wastewater Treatment and other services which include central drinking water treatment system, rehabilitation and plant automation since its incubation i.e. from the year 1964. The company has many years of experience and the group of experts are delivering their service in a most sincere and decent manner. ION exchange is a Supplier of a wide range of environmental solutions that include Water Treatment, liquid waste treatment & recycle, air pollution management, solid & hazardous waste management and more.

Conclusion

Today, significant innovative progressions in water treatment including monitoring and assessment help to ensure supply of high-quality safe drinking water. The source of the raw water and its Fundamental conditions generally determine the design and the steps needed in the Water Treatment Process.

Water treatment technology adopted the nature’s purifying process and enhanced it by cleaning water at a faster rate with greater control over finished quality and efficiency. When the water quality needs to be high, further treatment procedures would be applied. Hydromo is one of the major water and waste water treatment companies situated in Hyderabad specialized in planning, generation and supply of treatment systems, industrial machinery and luxury amenities for the water sector, custom-made to suit the client’s requirements. Hydromo is structured to supply propelled water treatment plants, RO systems, Sewage treatment plants, effluent treatment plants, water softeners, pumps, rain water systems and a lot more.

[ijprsteam-blog]

Formulation and Evaluation of Bilayer Tablets of Sustained Release Microspheres of Anti Diabetic Drugs

INTRODUCTION The oral route is the most commonly used route for drug administration. Although the different route of administration is used for the delivery of drugs, oral route remain the preferred mode. The oral route is one of the most popular routes of drug delivery due to its ease of administration, patient compliance, least sterility constraints and flexible design of dosage form1. Introduction to Sustained Release Formulation2, 3, 4 For decades an acute or chronic illness is being clinically treated through the delivery of drugs to the patients in form of some pharmaceutical dosage forms like tablets, capsules, liquids, creams, pills, aerosols, injectable, and suppositories. However, these conventional dosage forms have some drawbacks. When conventional immediate release dosage forms are taken on schedule and more than once daily, there are sequential therapeutically blood peaks and valley associated with taking each dose. It should be emphasized that the plasma level of a drug should be maintained within the safe margin and effective range. For this proper and calculated doses of the drug need to be given at different time interval by conventional dosage form (Fig. 1.1). To achieve and maintain the concentration of administered drug within a therapeutically effective range, it is often necessary to take drug dosage several times and these results in a fluctuating drug level in plasma.

Figure 1: Drug levels in the blood with I.V. administration and Controlled release deliver Mainly greater attention has been focused on the development of controlled or sustained release drug delivery systems with concomitant recognition of the therapeutic advantages of controlled drug delivery. Controlled drug delivery systems have been introduced to overwhelm the drawback of fluctuating drug levels associated with conventional dosage forms.   Terminologies5 Extended-release dosage form Delayed release dosage form Modified release dosage form Microspheres6 The term Microsphere is defined as a spherical particle with size varying with diameters in the micrometer range (typically 1μm to 1000μm (1mm), containing a core substance. The microspheres are characteristically free flowing powders consisting of proteins or synthetic polymers, which are biodegradable in nature, and ideally having a particle size less than 200 micrometers. Microsphere has been extensively studied for use as drug delivery systems, where they have been shown to protect sensitive macromolecules from enzymatic and acid degradation, and allow controlled release and tissue targeting of the formulated drug. Bilayer Tablet7 Dual release tablet is a unit compressed tablet dosage form intended for oral application. It contains two layers in which one layer having conventional or immediate release part of single or multiple actives; another layer is sustained or controlled release part of single or multiple actives‖. They are also called as Bilayer tablet, multi-layer matrix tablet. MATERIALS AND METHODS The following materials of Pharma grade or the best possible Laboratory Reagent (LR) were used as supplied by the manufacturer. MHCl, PHCl were obtained from Wanbury Ltd., Mumbai. HPMC 15K was obtained from Shreeji chemicals, Mumbai. Acetone, Methanol, Ethanol, Light liquid paraffin oil, Span 80 were obtained from SDFCL Mumbai. Petroleum Ether, Talc, Hydrochloric acid, MCC, Lactose were obtained from Pharma Link Hyderabad. Potassium Dihydrogen Phosphate, Sodium Hydroxide Pellets, Calcium Stearate were obtained from Amishi Drugs and Chemicals Ltd, Ahmedabad. RESULTS AND DISCUSSION Preformulation Studies Preformulation testing is the first step in the rational development of dosage forms of a drug substance. It can be defined as an investigation of physical and chemical properties of a drug substance alone and when combined with excipients. The overall objective of preformulation testing is to generate information useful to the formulator in developing stable and bioavailable dosage forms, which can be mass-produced. Identification of MHCl and PHCl Identification of MHCl and PHCl was carried out by FTIR spectrophotometry. pH Determination pH of MHCl and PHCl was determined using potentiometer by digital pH meter. Melting Point Determination The melting point of MHCl and PHCl was determined by taking a small amount of drug in a capillary tube closed at one end. The capillary tube was placed in a melting point apparatus and the temperature at which drug melts was recorded. This was performed thrice and an average value was noted. Solubility Studies An excess amount of the drug was taken and dissolved in a measured volume of distilled water in a glass vial to get a saturated solution. The solution was sonicated and kept at room temp for the attainment of equilibrium. The concentration of MHCl and PHCl of in the filtrate was determined spectrophotometrically by measuring at 233 nm and 269 nm respectively. Drug Excipient Compatibility Testing FTIR spectroscopy was performed on Fourier transformed infrared spectrophotometer (IR-Affinity-1, Shimadzu, Japan). The pellets of drug and potassium bromide were prepared by compressing the powders at 20 psi for 10 min on KBr-press and the spectra were scanned in the wave number range of 4000- 400 cm-1. FTIR study was carried out on MHCl, PHCl, Polymer, physical mixture of PHCl and polymer and MHCl and polymer. Preparation of Standard Calibration Curves Preparation of Standard Calibration Curves of MHCl Metformin calibration curve in water at 233 nm 100 mg of MHCl was dissolved in small amount of water and volume was made up to 100ml using the same. From the stock solution, serial dilutions were done to obtain solutions in the concentration ranging from 10 to 100 mcg/ml. The absorbance of the solution was measured at 233 nm using a UV-visible spectrophotometer. A graph of concentration v/s absorbance was plotted. Similarly, a standard calibration curve of MHCl was prepared in Phosphate buffer pH6.8 and Hydrochloric acid buffer pH 2 by using above said method. Preparation of Standard Calibration Curve of PHCl at 269nm PHCl calibration curve in pH 2 buffer at 269 nm 50 mg of PHCl was dissolved in small amount of water and volume was made up to 100ml using the same. From the stock solution, serial dilutions were done to obtain solutions in the conc. ranging from 10 to 50 mcg/ml. The absorbance of the solution was measured at 269 nm using a UV-visible spectrophotometer. A graph of concentration v/s absorbance was plotted. Similarly, a standard calibration curve of PHCl was prepared in Phosphate buffer pH6.8 and Hydrochloric acid buffer pH 2 by using above said method. Selection of Directly Compressible Material for Preparation of Bilayered Tablets of MHCl Microspheres and PHCl2, 8, 9 The bilayered tablets were prepared by direct compression method.  Blends for both layers were prepared separately by weighing and mixing a required quantity of ingredients in geometric proportions for 10 mins. Two different directly compressible materials viz. microcrystalline cellulose and dibasic calcium phosphate were used to compress microspheres to prepare bilayered tablets. The MHCl layer was pre-compressed by hydraulic pellet press by compression force 5 kg/cm2. Then the PHCl layer was added and the tablet was finally compressed with compression force 25 kg/cm2 and dwell time 15 secs. The formula for the composition of MHCl layer and PHCl layer is given in Table 1. Table 1: Composition of bilayer tablet of MHCl microspheres and PHCl Ingredient quantity in mg/tablet MP1 MP2 M1 P1 M2 P2 MHCl PHCl 130 25 130 25 HPMC 15k HPMC 15k 25 60 25 60 MCC MCC 100 - - 40 DCP DCP - 40 100 - Lactose Lactose 35.5 65 35.5 65 Ca Stearate Ca Stearate 3.5 6 3.5 6 Talc Talc 10 4 10 4 Avg. wt. bilayer tablet in mg/tablet 500 500 Evaluation of Bilayered Tablets of MHCL Microspheres and PHCL 8 Weight Variation Test

20 tablets were weighed individually, the average weight of tablets was calculated and their upper and lower limits were calculated and Percentage weight variation was calculated using the following formula 1.  Drug Content

The drug content is determined spectrophotometrically. The tablets were weighed and powdered. An accurately weighed quantity of the sample was taken and extracted in Hydrochloric acid buffer pH 2 and the content was determined using a UV spectrophotometer at 233nm and 269nm. The amount of drug entrapped in the microspheres was calculated using the formula. Hardness The Pfizer hardness tester was used to determine the tablets hardness. The tablets were held between a fixed and moving jaw, the body of the Monsanto hardness tester carrier an adjustable scale which was set zero against an index mark fixed to the compression plunger when the tablets were held between the jaws. The load was gradually increased until the tablets fractured. The value of the load at that point gave a measure of the tablets hardness. Hardness 5 tablets were determined and the average result was tabulated. Disintegration Time The test was carried out on 5 tablets using tablet disintegration tester ED-20 distilled water at 370C± 20C  was used as disintegration media and the time in seconds taken for complete disintegration of the tablets with no palpable mass remaining in the apparatus was measured in seconds. Friability

The friability of the tablets was measured in a Roche friabilator. Tablets of a known weight (W0) or a sample of 20 tablets are deducted in a drum for a fixed time (100 revolutions) and weighed (W) again. Percentage friability was calculated from the loss in weight as given in a formula 2. The weight loss should not be more than 1%. In vitro Drug Release Study of Bilayered Tablets of MHCl and PHCl 7, 10 In vitro drug release study of bilayered tablets was carried out using USP XXIII basket type dissolution apparatus in two stages. Stage I : Medium: pH 2 hydrochloric acid buffer Time: 2 hours RPM: 100 Stage II : Medium: Phosphate buffer pH 6.8. Time: 10 hours RPM: 100 Samples of 10 ml each were withdrawn at 1 hr intervals for 12 hours. and analyzed spectrophotometrically at first derivative at 269 nm to determine the concentration of PHCl present in the dissolution medium. And samples were analyzed spectrophotometrically at 233nm to determine the concentration of MHCl in the dissolution medium. The initial volume of the dissolution fluid was maintained by adding 10 ml of fresh dissolution fluid after each withdrawal. Kinetics of Drug Release The dissolution profile of all the batches was fitted to Zero order, First order and Higuchi to ascertain the kinetic modeling of the drug release. The method of Bamba et al. was adopted for deciding the most appropriate model. Zero-order In many of the modified release dosage forms, particularly sustained or controlled release dosage forms (those dosage forms that release the drug in planned, predictable and slower than the normal manner), is zero-order kinetic and can be calculated by formula 3, m = k x t …………..3 Korsmeyer Peppa's equation: Mt/M∞ = Ktn……..4 Where Mt is the amount of drug released at time t, M∞ is the amount of drug released after an infinite time, k is a kinetic constant incorporating structural and geometric characteristics of the tablet, and n is the diffusional exponent indicative of the drug release mechanism. In short, the results obtained from in vitro release studies were plotted in four kinetics models of data treatment as follows: Cumulative percentage drug release Vs. Time (zero order rate kinetics) Log cumulative percentage drug retained Vs. Time (first-order rate kinetics) Cumulative percentage drug release Vs. √T (Higuchi’s classical diffusion equation) Log of cumulative percentage drug release Vs. log Time (Peppa’s exponential equation) Evaluation of Bilayered Tablets of MHCL Microsphere and PHCL The selection of directly compressible material is critical in case of tableting of microspheres. Two directly compressible materials were taken in the study described in Table 1 and the tablets were evaluated for drug content, hardness, disintegration time, weight variation and friability. The results of these tests are shown in Table 3. Drug Content                                                             The drug content was found to be in the desired limit for all the tablets. MHCl drug content was found to be higher (82.61%) in case of batch MP2 containing DCP as the directly compressible material and batch MP1 containing MCC as directly compressible material showed 81.54% drug release. In case of PHCl content batch, MP2 showed maximum drug content at 94.35%. Disintegration Time The disintegration time was found to be higher in case of Batch MP1 was 65 sec. and batch MP2 was found to be 56 sec. Friability Friability was found to be less in case of tablets prepared with directly compressible material MCC than DCP. Hardness The hardness of all the tablets was found to be around 4-4.1 Kg/cm2. In vitro Dissolution Study

Figure 2: IR Spectrum of MHCl The results of the dissolution of bilayered tablets were shown in Table 4 and 5 and Fig. 2. All the tablets showed good release in case of PHCl layer. Batch MP2 were showing the maximum release of MHCl from microspheres layer containing DCP direct compressible material. Results Preformulation Studies Identification The IR spectrums of pure drugs were found to be similar to the standard spectrum of MHCl and PHCl. The spectrum of MHCl and PHCl shows the following functional groups at their frequencies as shown in Fig. 3 and Table 6. pH Determination The pH of MHCl and PHCl was found to be 6.68 and 5.5 respectively. Melting Point Determination The melting point of MHCl and PHCl was found to be 222ºC and 188ºC respectively. Solubility Study MHCl was found freely soluble in water; soluble in ethanol and methanol; sparingly soluble in chloroform and practically insoluble in acetone. PHCl was freely soluble in N-N dimethylformamide and 5N acetic acid; slightly soluble in ethanol, acetone, and acetonitrile and practically insoluble in water. Drug Polymer Interaction (FTIR) Study The results of FTIR study for MHCl, HPMC 15k, a combination of MHCl and HPMC 15k, PHCl, and the combination of PHCl and HPMC. Table 2: Results of IR interpretation from spectra Sl. No. IR Spectrum Peaks cm-1 Groups Stretching / Deformation 1 MHCl 2814.24 C – H Stretching 1629.9 C = N Stretching 1577.82 N – H Bending 1386.86 C – N Stretching 729.12 Cl Stretching 2 Physical mixture of MHCl and polymer 2939.61 C – H Stretching 1570.11 N – H Bending 1415.80 C – N Stretching 1267.27 C – O Stretching 3373.61 O – H Stretching 3 PHCl 2924.18 C – H Stretching 1614.47 C = N Stretching 1504.53 N – H Bending 1390.72 C – N Stretching 717.54 Cl Stretching Evaluation of Bilayered Tablets of MHCl Microspheres and PHCl Table 3: Evaluation data of bilayered tablets of MHCl microspheres and PHCl Batch Weight variation (mg) mean ±SD (n=10) Hardness (kg/cm2) (n=5) Friability (%) D.T (sec) (n=5) MHCl content (%) PHCl content (%) MP1 500.2±1.48 4 0.87 59 81.54 92.10 MP2 500.4±2.07 4 0.73 63 82.61 94.35 In vitro dissolution study of bilayered tablets of MHCl microspheres and PHCl Stage 1: In vitro release study for PHCl in pH 2 hydrochloric acid buffer and Phosphate buffer pH 6.8. Table 4: In vitro release data of PHCl layer from bilayered tablets Sl.No. Time (min) % Cum. drug release   MP1±SD MP2±SD 1 0 0 0 2 20 31.66±0.56 43.94±0.47 3 40 41.22±0.88 57.27±0.98 4 60 44.03±1.35 63.03±0.85 5 80 52.58±0.65 76.74±1.20 6 100 77.11±0.75 81.75±1.12 7 120 89.45±1.25 85.02±0.65 Stage 2: In vitro release study for MHCl in pH 2 hydrochloric acid buffer and Phosphate buffer pH 6.8. Table 5: In vitro release study Sl. No. Time (hrs) % Cum. drug release MP1±SD MP2±SD 1 0 0 0 2 1 12.63 ± 0.35 13.16 ± 1.16 3 2 21.92 ± 0.40 26.03 ± 0.98 4 3 28.74 ± 0.80 30.53 ± 0.80 5 4 30.85 ± 0.98 35.71 ± 1.25 6 5 37.76 ± 0.75 41.24 ± 1.30 7 6 43.68 ± 1.20 48.15 ± 0.75 8 7 48.36 ± 0.90 51.58 ± 0.35 9 8 52.29 ± 0.85 56.74 ± 0.45 10 9 57.50 ± 1.12 61.71 ± 0.20 11 10 62.33 ± 1.35 67.37 ± 0.50 12 11 68.18 ± 0.60 72.31 ± 0.65 13 12 70.69 ± 0.75 78.90 ± 1.13 CONCLUSION

Figure 3: In vitro release profile of bilayered tablets of MHCl microspheres and PHCl The present investigation showed that the HPMC can be used to encapsulate MHCl by a solvent evaporation method. The effect of the drug to polymer ratio was studied and form the results, the following conclusions can be made: On the basis of in vitro release studies, E3 was selected as an optimized formulation for designing sustained release formulation. And For further study batch, E3 was used for tableting. For the immediate release PHCl layer it can be concluded that 4% of the HPMC (batch T2) showed maximum drug release hence batch T2 was selected for further process. Studies on the directly compressible materials revealed that DCP was the best directly compressible material than MCC for compressing of MHCl microspheres. The results of the kinetic study showed that the compressed bilayered tablets followed zero order kinetics and coupling of diffusion and erosion mechanism so-called anomalous diffusion mechanism. REFERENCES Gilbert S. Banker, Neil R. Anderson., tablets. In Leon Lachman, Herbert Liebermann, Joseph L Kanig. (Edition), the theory and practice of Industrial Pharmacy, 3rd ed. Lea and Febiger, Philadelphia, 1987, 293-94. PMid:3580553 Chien, Y. W. (1990). Controlled and modulated-release drug delivery systems, In Swarbrick and JC Boyland (Ed.). Encyclopedia of Pharmaceutical Technology. New York: Marcel Dekker, Inc; 281-313. Brahmankar, D. M., Jaiswal, S. B. (2000). Biopharmaceutics and Pharmacokinetics-A treatise. 1st Ed. Delhi: Vallabh Prakashan; 335-75. Gudsoorkar, V. R., Rambhau, D. (1993). Sustained release of drugs. The Eastern Pharmacist, 36(429), 17-22. Robinson, J. R., Lee, L. H. (1987). Controlled Drug Delivery: Fundamentals and Applications, 2nd Ed; 312-31. Available on online URL; wikipedia.com Gilbert S. Banker, Neil R. Anderson., tablets. In Leon Lachman, Herbert Liebermann, Joseph L Kanig. (Edition), the theory and practice of Industrial Pharmacy, 3rd ed. Lea and Febiger, Philadelphia, 1987, p. (a) 293-94, (b) 330-31, (c) 430-31. Watts, P. J., Davies, M. C., & Melia, C. D. (1990). Microencapsulation using emulsification/solvent evaporation: an overview of techniques and applications. Critical reviews in therapeutic drug carrier systems, 7(3), 235-259. PMid:2073688 Paint and Coatings Industry Magazine, January 1st, 2010: Opaque Polyethylene Microspheres for the coatings applications. Vyas S, Khar R. Targeted and Controlled drug delivery: Novel carrier systems. First edition, CBS Publishers; New Delhi; 2006. p. 417-57. PMid:17722276 , PMCid:PMC2676632 Read the full article

[uniquequeenkryptonite-blog]

Construction Sand and Gravel

You probably don’t have a great deal of attention that you can devote to studying about sand and gravel. However, a brief examine of sand and gravel can display lots about the difficulty. Sand and gravel deposits come from river channels, river floodplains, and glacial deposits. HMR Traders Sand Suppliers produce sand and gravel, where more than one thousand million heaps are produced each 12 months. The Hyderabad has good sized, first-class deposits of sand and gravel, together with the generation that permits it to system the fabric into nearly any fine for nearly any utility.

As one of the most reachable herbal resources, sand and gravel has been used since the earliest days of civilization by and large as a construction fabric. At the start of the twentieth century, the production of production sand and gravel turned into surprisingly small and its makes use of restricted. Today, annual sand and gravel manufacturing tonnage ranks second within the non-gas minerals enterprise after overwhelmed stone. Sand supplier in Hyderabad one of the main sand and gravel producers, predominantly sells cloth to the development enterprise.  Production sand and gravel are used to make concrete, for road creation, for blending with asphalt, as creation fill, and inside the production of creation substances like concrete blocks, bricks, and pipes. Sand and gravel also can use to make roofing shingles; on icy roads inside the iciness for more advantageous traction; as panorama material; on driveways or parking lots; and also for water filtration.

The sand itself comes in numerous sizes of grain. It's miles used for normal functions and is derived from many assets. Sand from the seaside comes in very first-rate grains and is utilized in playgrounds, volleyball courts, golfing direction bunkers and sandboxes. It may additionally be used in sandbags or to line the floors of arenas and different surfaces. Sand is primarily quartz, formed via weathering of igneous rocks like granite. Quartz is floor down, however it doesn’t destroy down chemically. After a while, all that’s left are the tiny grains which might be deposited in riverbeds and beaches. For more information, please visit our site http://www.sandsuppliers.in/

[filtration-products]

5 groups advance to last spherical of $1.75M Water Abundance XPRIZE

LOS ANGELES, CA, MARC 28, 2018 — XPRIZE — the world’s leader in building and working incentive competitions to fix humanity’s grand difficulties — has named the five finalist groups advancing in the $1.75M Water Abundance XPRIZE, a two-calendar year competition aimed at tackling world wide drinking water scarcity.

Sponsored by Australian Assist and the Tata Team, the Water Abundance XPRIZE incentivizes groups from all-around the environment to make and produce groundbreaking systems that can extract a least of 2,000 liters of drinking water for each working day from the atmosphere employing 100 percent renewable vitality, at a price tag of two cents for each liter.

“Water is our lifeblood. With alarming drinking water shortages impacting livelihood all-around the environment, we are in dire will need of decentralized and democratized drinking water breakthroughs now more than at any time,” claimed Zenia Tata, vice president of Worldwide Effects Method at XPRIZE. “The promising prototypes presented by these five finalist groups bring us a person phase nearer in direction of discovering a price tag-productive resolution for extracting drinking water from thin air and providing on-demand accessibility to drinking water, anytime and anyplace.”

[Native Advertisement]

The five finalists ended up selected primarily based on submissions of complex documentation, check outcomes, and video clip of a resolution prototype that can extract drinking water from the atmosphere employing any source of vitality and without any requirement for least drinking water output price tag for each liter. The finalists consist of startups, professors, expert experts and engineers. The five finalists will share a $250,000 milestone prize purse.

The five advancing groups are:

Hydro Harvest Procedure (Newcastle, Australia) – Led by the College of Newcastle’s Professor Behdad Moghtaderi, the team is likely again to basic principles to produce a easy, vitality-efficient and price tag-productive unit — offering communities throughout the world the ability to harvest their possess clean drinking water.

JMCC WING (South Position – Island of Hawaii) – Led by James McCanney, M.S., the team is powering the JMCC WING, LLC line of industrial Atmospheric Water Generators (AWGs) with the JMCC WING, a higher effectiveness wind vitality technique, to extract drinking water from the atmosphere.

Skydra (Chicago, IL) – Led by Jacques Laramie, Nathan Taylor, and Chris Wlezien, the team has utilized a hybrid resolution that makes use of equally pure and engineered programs to condense drinking water out of the air.

Uravu (Hyderabad, India) – Led by Swapnil Shrivastav, the team is acquiring a fully off-grid drinking water from air unit, spinning alongside one another the magic of product sciences and solar thermal vitality.

The Veragon & ThinAir Partnership (London, United Kingdom) – Led by Laura Dean, the team has formulated a partnership with the vital goal of revolutionizing the functionality of Atmospheric Water Generators to produce higher good quality, mineralized consuming drinking water at the issue of will need, in an economically and environmentally sustainable manner.

The Water Abundance XPRIZE finalists ended up selected from a industry of 98 groups by an worldwide and independent judging panel of seven market industry experts in mechanical engineering, drinking water treatment, ocean vitality, strategic style and design and emerging systems. Judges consist of: Mike Claerhout, RGL Reservoir Management Nicholas Davis, Globe Economic Discussion board David Ginley, Ph.D., Countrywide Renewable Energy Laboratory Eric Hoek, Ph.D., Water Earth David Eire, Ph.D., ThinkPlace Purnima Jalihal, Ph.D., Countrywide Institute of Ocean Technological know-how, India and Matthew Stuber, Ph.D., College of Connecticut and WaterFX.

The finalists will start out spherical 2 tests in July 2018 at a area to be identified. Through this period, groups must absolutely reveal that their unit can extract a least of 2,000 liters of drinking water for each working day from the atmosphere employing 100 percent renewable vitality, at a price tag of no more than two cents for each liter. At the stop of this tests period, the team whose resolution allows the finest ability to make decentralized accessibility to drinking water – offering people the energy to accessibility clean drinking water anytime and anywhere they will need it – will receive the Grand Prize of $1.5 million, to be introduced in August 2018.

For more data about the competition construction, vital dates, and the finalist groups be sure to go to drinking water.xprize.org.

About XPRIZE XPRIZE, a 501(c)(3) nonprofit, is the world wide leader in building and implementing ground breaking competition designs to fix the world’s grandest difficulties. XPRIZE makes use of a one of a kind mixture of gamification, group-sourcing, incentive prize theory, and exponential systems as a formula to make 10x (vs. 10%) influence in the grand obstacle domains experiencing our environment. XPRIZE’s philosophy is that—under the ideal circumstances— igniting fast experimentation from a wide variety of varied lenses is the most efficient and productive approach to driving exponential influence and methods to grand difficulties. Energetic competitions consist of the $30M Google Lunar XPRIZE, the $20M NRG COSIA Carbon XPRIZE, the $15M Worldwide Learning XPRIZE, the $10M ANA Avatar XPRIZE, the $7M Shell Ocean Discovery XPRIZE, the $7M Barbara Bush Foundation Adult Literacy XPRIZE, the $5M IBM Watson AI XPRIZE, the $1.75M Water Abundance XPRIZE and the $1M Anu and Naveen Jain Women’s Basic safety XPRIZE. For more data, go to www.xprize.org.

Summarization of our web-site: Filtration-Items.com web web-site captures the clean tales, investigate and separation advancements ideal from the purification trade. Filtration-Items keeps you savvy on treatment and all the related complex split throughs which include wound filter cartridges, pleated filter cartridges, soften blown depth cartridges, sock filtration, Pre-RO filtration, from manufacturers this kind of as Lakos utilised in air treatment, and just about anything else the separation vocation has to announce.

from Filtration Products https://ift.tt/2pNDSww