thexphial - Tumblr blog

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“Commander Vimes didn't like the phrase 'The innocent have nothing to fear', believing the innocent had everything to fear, mostly from the guilty but in the longer term even more from those who say things like 'The innocent have nothing to fear'.” -- Discworld (Snuff)

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holy shit is this gorgeous.

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oh fuck this is a really good hill i gotta die on this

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🐱 🐦

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all goofing aside I genuinely don't understand the urge to reimagine Taylor Allison Swift as a secretly queer icon when the pop music scene(TM) is like. literally overflowing with women who actually like women. Gaga and Kesha and Miley and Halsey are right there. Rina Sawayama and Hayley Kiyoko and Rebecca Black and Kehlani and Victoria Monét and Miya Folick if you're willing to get slightly less top 100. Janelle and Demi for them nonbinary takes on liking girls. like what are we doing here. like I'm not even saying you can't enjoy Taylor but why would you hang all your little gay hopes on her.

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I laughed so fucking hard at this

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The wildest thing about Burrow's End, is that if Viola had used her Divine Sense even once, she would've had the most horrifying realisation

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i'm sorry but this is the only submission to this trend that i'll consider giving any thought to

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Seeing a post that you know a mutual will like and reblogging it to add enrichment to their dash like giving a tiger in a zoo a cardboard box

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Everything is like “QUEER history” and “List of QUEER young adult books” or “Top 10 QUEER movies” and queer this and queer that and for the love of god please just say LGBT.

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body paintings by Karen Turner

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Okay, this could really be something!

“This is one of the most exciting things we’ve seen in a really long time,” said Shaw. “This is a really finely honed tool. To be able to sit there and say to your patients that you’re offering them something that’s effectively like the Fat Duck at Bray versus McDonald’s – it’s that level of cordon bleu that’s coming to them … The patients are really excited about them.” The vaccine is an individualised neoantigen therapy. It is designed to trigger the immune system so it can fight back against a patient’s specific type of cancer and tumour. Known as mRNA-4157 (V940), the vaccine targets tumour neoantigens, which are expressed by tumours in a particular patient. These are markers on the tumour that can potentially be recognised by the immune system. The jab carries coding for up to 34 neoantigens and activates an anti-tumour immune response based on the unique mutations in a patient’s cancer. To personalise it, a sample of tumour is removed during the patient’s surgery, followed by DNA sequencing and the use of artificial intelligence. The result is a custom-built anti-cancer jab that is specific to the patient’s tumour.

...If your tech vocabulary's up to it, see also the abstract/article in the Lancet.

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Oliver Marinkoski

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Please don’t pay for his music.

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i need like ten more hours of this.

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This is part of my ongoing Discworld jacket embroidery project. Of course Great A'Tuin has to be on there. And of course it has to be the biggest one of them all.

I'm going to put the finished product in my masterpost, but I'm so proud of the thing that I have to put it in an extra post beforehand. Enjoy!