An experienced medical professional in New York City, Dr. Timothy Niewold has driven research activities as the Vice Chair of Medicine for Research at the Hospital for Special Surgery since 2022. Dr. Timothy Niewold further serves as the Barbara Volcker Center for Women and Rheumatic Diseases. Dr. Timothy Niewold developed a new grant mentoring program at the hospital, which resulted in a considerable increase in extramural funding for the Department of Medicine. He has also secured funding for his independent research lab at the hospital, which focuses on understanding the disease pathogenesis of autoimmune conditions such as lupus. At the University of Illinois College of Medicine, Dr. Timothy Niewold was a James Scholar for Independent Study. He subsequently completed his residency and fellowship at the Mayo Clinic and the Hospital for Special Surgery, top internal medicine and rheumatology programs. When not engaging with professional organizations such as the American Society for Human Genetics, he enjoys meditating and spending time outdoors.
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The Impact of Lupus on Womens Health

Lupus, a chronic autoimmune disease, disproportionately affects women, with approximately 90% of diagnosed cases occurring in females. This apparent gender disparity influences many aspects of women's physical well-being and health.
One of the primary concerns for women with lupus is its impact on reproductive health. Cytoxan, or cyclophosphamide, can lower fertility when it is used to treat lupus. The medication Lupron can be used to protect ovarian function and lower risks.
Preterm birth and preeclampsia are more common among women with lupus. Rheumatologists and obstetricians have work together to provide care to try to prevent these outcomes.
Systemic inflammation linked to lupus increases the risk of atherosclerosis, raising heart disease risk. At an earlier age, lupus increases women's likelihood of cardiovascular issues. Given their higher risk, women with lupus should routinely check with their doctors about heart disease risk, and modifiable risk factors, including hyperlipidemia and hypertension.
Another critical issue is renal involvement, or lupus nephritis—a disorder in which the kidneys are inflamed—affects a considerable number of women. This problem may lead to kidney failure if not adequately treated. This often appears as proteinuria, hematuria, and hypertension. Kidney function and prevention of long-term damage depend on routine urine tests to detect early kidney disease and immunosuppressive treatment when kidney disease is diagnosed.
Lupus-related myalgias or muscle aches and fatigue significantly affect women's quality of life. Muscle aches, joint pain, and tiredness can impede daily living, work, and socializing. Flares often aggravate these symptoms. To remain functional and healthy, it is important to remain considering with medical therapy, and frequently physical therapy, and lifestyle adjustments can be helpful as well.
Anxiety and depression are common in people with lupus, and this may result from the inflammation in the disease, and the uncertainty and difficulty of the disease contributes as well. Emotional support and coping mechanisms from support groups, counseling, and education, can help manage this chronic illness.
Because of the lupus disease process and therapies like corticosteroids, which, over time, weaken bones, women with lupus are more likely to have osteoporosis. Given a higher risk of fractures, women must actively monitor their bone health. Reducing risk includes weight-bearing activities, calcium and vitamin D supplements, and routine bone density tests. Long-term musculoskeletal health depends on maintaining mobility through physical therapy and a planned exercise program since lupus can cause joint stiffness and pain.
For women suffering from the illness, cognitive dysfunction—often known as "lupus fog— can be another obstacle. Many people struggle with memory, attention, and difficulties with language recall, which can interfere with daily life. Although the specific origin of this neurological disorder are unknown, brain and nervous system inflammation may be responsible. For women with lupus, visits with mental health professionals, consistent routines, planners, and reminders can help.
Emerging studies point to hormonal and genetic elements contributing to the higher prevalence of lupus among women. Variations in estrogen could impact the immune system, either starting or exacerbating lupus symptoms. Designing focused and unique treatments for women depends on an improved understanding of these pathways.
Given the many effects of lupus on the body, women should manage lupus holistically using a comprehensive strategy. This approach should include medical attention, reproductive planning, cardiovascular health, renal surveillance, pain treatment, and psychological support. By customizing treatments to fit lupus women's challenges, healthcare professionals can help to enhance patient outcomes and quality of life.
Understanding how lupus affects women's health requires a thorough and customized treatment plan. Combining medical management with supportive services and gender-specific research can help the healthcare community better serve women with this complicated autoimmune disease.
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ACR - Advancing Professional Excellence

The ACR, American College of Rheumatology, advances rheumatology by empowering its 10,000+ professionals. Guided by innovation, collaboration, and community, the ACR focuses on strategies that drive innovation within the specialty, meeting member needs, and equipping the rheumatology workforce with essential tools.
The Association of Rheumatology Professionals (ARP), an ACR division, serves a diverse membership, including advanced practice nurses, psychologists, researchers, and other allied health professionals. The College established the ARP to increase the pool of qualified rheumatology professionals, enhance their practice environments, promote ARP offerings, and facilitate professional development through educational and volunteer opportunities. The ARP works with the Rheumatology Research Foundation, which spearheads research, supports education and training, and promotes inter-professional collaboration.
The ACR's governing body is its board of directors, composed of medical specialists who oversee the College's business affairs and committees and promote its mission. Specialized ACR committees oversee collaborative initiatives, communications and marketing, corporate relations, ethics and conflicts of interest, finance, education, and specific disease-related areas.
As a professional membership organization, the ACR supports its members with numerous education and networking opportunities. Volunteering advances the College's mission by enabling the contribution of skills, time, and expertise. Opportunities exist across all ACR organizations, including the ARP and the Rheumatology Research Foundation. The Volunteers to Expand Rheumatology Access (VERA) initiative specifically addresses the needs of patients with rheumatic diseases, connecting rheumatology professionals with opportunities to provide care to uninsured and underinsured individuals. Through VERA, volunteers offer remote assessments and mentorship, educate other healthcare providers, and contribute to improved patient outcomes. This involvement provides volunteers with valuable experiences.
The ACR emphasizes education and career development to enhance patient care. Members benefit from meetings and webinars that facilitate learning and networking and online learning programs like the Virtual Lupus Clinic and Rheum4Science. The ACR also supports collaborative and reproductive health initiatives to treat complex illnesses, ensure health equity, and address unmet needs related to fertility and pregnancy. Resources such as continuing medical education, CareerConnect (a platform for job listings and alerts), and a rheumatology curriculum designed for new and transitioning nurse practitioners and physician assistants are also available to support career development.
Advocacy is a key focus area of ACR, with the College working to represent professionals in its field and patients with rheumatic disease. ACR engages with federal and state legislators and policymakers, educating them on the impact of proposed legislation. Each year, its members advocate for key policy priorities, including improved access to quality care, adequate healthcare professional reimbursement, drug pricing transparency, and research funding. The ACR also encourages participation in advocacy efforts by contacting policymakers, attending relevant events, and joining local/state societies.
The ACR website has valuable resources for practitioners and patients. The site offers practice management support for practitioners, including compliance information, coding and billing resources, and fact sheets outlining rheumatology care team roles. On the other hand, patients and caregivers can leverage the "find а rheumatology provider" tool to locate a specialist, access information on rheumatic diseases, and explore disease management and treatment options.
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