#BioResearch

[bio-basic-inc]

Streamline your protein extraction process with Bio Basic's Bacterial Protein Lysis Buffer. Designed for efficient protein extraction from E. coli without mechanical disruption, it enhances yields of soluble proteins and inclusion bodies. Each kit includes lysozyme and DNase I to boost extraction efficiency, while PMSF and DTT maintain protein stability. Simplify your research with this reliable solution.

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[marketingreportz]

Real-time PCR Market - Forecast(2024 - 2030)

𝐑𝐞𝐚𝐥-𝐓𝐢𝐦𝐞 𝐏𝐂𝐑: 𝐄𝐬𝐬𝐞𝐧𝐭𝐢𝐚𝐥 𝐓𝐨𝐨𝐥 𝐟𝐨𝐫 𝐌𝐨𝐝𝐞𝐫𝐧 𝐌𝐨𝐥𝐞𝐜𝐮𝐥𝐚𝐫 𝐁𝐢𝐨𝐥𝐨𝐠𝐲 𝐄𝐱𝐩𝐥𝐚𝐢𝐧𝐞𝐝

The global real-time PCR (qPCR) market is experiencing significant growth, driven by several key factors. The market, valued at $22.03 billion in 2024, is projected to reach $27.78 billion by 2028. This growth is largely due to the increasing prevalence of infectious diseases, the rise of cancer diagnostics, and expanding research in genomics.

The method that creates multiple copies of a particular DNA region in vitro uses the polymerase chain reaction. The technique relies on a DNA polymerase known as TAQ polymerase, which is thermostable. Thermus aquaticus is used to produce this polymerase. They occupy hot springs and hydrothermal vents. The target region to be reproduced is produced in large numbers by the PCR reaction, which involves repeat cycles at a range of temperatures.

Real-time PCR systems are laboratory instruments used to increase the number of copies of specific DNA segments. The rising prevalence of chronic and infectious diseases is driving the growth of the market for real-time polymerase chain reaction (PCR). Furthermore, forensics, diagnostics, and proteomics research advancements are creating potential growth opportunities for the real-time polymerase chain reaction (PCR) market.

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The polymerase chain reaction (PCR) has been used and shown to be effective in detecting minute amounts of a wide range of infectious diseases. The best conditions for amplification vary depending on the organisms of interest. PCR was used as a rapid and sensitive method for detecting infectious agents, and three assay systems were developed, one for the amplification of human T cell leukaemia virus type I, one for Mycobacterium tuberculosis, and one for Mycoplasma pneumoniae. These all factors will propel the market.

The increased use of the polymerase chain reaction for cancer diagnosis is expected to drive market growth in the coming years. All of these factors are responsible for creating a greater demand for this technique in the coming years, research and development activities for providing innovative molecular biology and forensic science as there has been a great demand for genetic engineering as well as personalized medicines.

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The global real-time PCR (qPCR) market is experiencing significant growth, driven by several key factors. The market, valued at $22.03 billion in 2024, is projected to reach $27.78 billion by 2028. This growth is largely due to the increasing prevalence of infectious diseases, the rise of cancer diagnostics, and expanding research in genomics. Real-time PCR remains a vital tool in healthcare, pharmaceuticals, and biotechnology for applications such as early disease detection, personalized medicine, and molecular diagnostics​

COVID-19 had a substantial impact on the PCR market, as demand for reliable diagnostic tools surged. The pandemic underscored the importance of real-time PCR for detecting viral infections like SARS-CoV-2, making it an essential part of disease management worldwide. This trend continues to fuel demand, especially as the technology evolves with innovations like digital PCR and multiplex assays

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Regionally, North America dominates the market due to its strong healthcare infrastructure and high prevalence of diseases like hepatitis and HIV. However, the Asia-Pacific region is expected to see the fastest growth, with rising patient awareness and investments in healthcare across countries like China, Japan, 

More about Real-time PCR Market report click here 

[labtroncc]

Mini centrifuge

Labtron Mini centrifuges, upgraded to high-quality models, offer speeds of 7000 rpm and 12000 rpm. They are compact, space-saving, and easy to operate. Suitable for tubes ranging from 0.2 ml to 2.0 ml, they support various biological studies. Their compact design ensures ease of use and efficient operation in limited spaces.

[biochemltd]

https://www.biochemltd.in/buy-horseshoe-crab-blood/

[crimson-biotechnology]

Studies on the Isolation, Characterization and Extra-Cellular Enzymatic Activities of the Pathogen Helminthosporium Oryzae Causing Brown Spot Disease of Rice_ Crimson Publishers

Studies on the Isolation, Characterization and Extra-Cellular Enzymatic Activities of the Pathogen Helminthosporium Oryzae Causing Brown Spot Disease of Rice by Archana U Singh  In Journal of Biotechnology & Bioresearch

Abstract

Rice is an important Cereal and staple food for human population. In the present study a major fungal pathogen (Helminthosporium oryzae) causing brown spot disease of Rice was studied. Isolation, Characterization and Extra-cellular enzymatic activities of the pathogen Helminthosporium oryzae was carried out for confirming pathogenic nature of fungus causing Brown Spot Disease of Rice.

For more open access journals in Crimson Publishers please click on: https://crimsonpublishers.com/jbb/

Read more articles in our site: https://crimsonpublishers.com/jbb/index.php

[manorpunk]

2️⃣

‘Comprador’ refers to an agent of a large multinational corporation whose typical job responsibility is taking a small underdeveloped nation and turning it into a vending machine for a natural resource - oil, coffee, coal, minerals - then getting that nation so dependent on selling those raw materials to that company that they effectively control it.

Unrelatedly, the Global Logistics Network was the single largest anything of 2069.

They weren’t a monopoly, no, no, no. They were… you see, the crowded and fragile system of intercontinental shipping was simply too important to be left in the hands of any single nation. You all saw what happened when the Brits monopolized it, and when the US monopolized it after them. You’ve seen how nations owning major canals turns them into a hive of corruption. Shipping belongs to the world, which means it belongs to the GLN.

They were headquartered in Qingdao, a major city in the Shandong province of China. Don’t be fooled, China fumbled the past few decades as much as everyone else, but every institution needs a head, and every head needs a headquarters, and the headquarters of the Global Logistics Network were located in Qingdao. The complex of skyscrapers that comprised GLNHQ was large and populous enough to form its own city-state, a closed loop of offices, gyms, fabricators, dormitories, labs, shops, copackers, cafeterias, and warehouses. You could spend your whole life there without ever setting foot on the earth itself. Many did.

Such was the Global Logistics Network. Like capitalism rising centuries ago from the sclerotic and shambling remnants of feudalism, the GLN rose from the old ways of hyper-financialized over-leveraged capitalism to create something new, something so new it didn’t even have a name yet. Much like the transition from feudalism to capitalism, things were better overall, but good lord, what a low bar to clear.

Towering above it all at the top floor of the central skyscraper sat Meng “Harold” Jianli, sole co-founder of the GLN. One might wonder how someone could be a ‘sole co-founder,’ and the answer was that the GLN was so powerful and omnipresent that its leader could have called himself a living god for all the power that sat upon his person. He certainly had more power than those who had historically claimed the title of living god.

But Meng “Harold” Jianli was no god, living or otherwise. Despite the vast power seated upon his person, or perhaps because of it,he looked rather disheveled, with a jowly face like splotchy old parchment, a sagging belly, and a crudely functional flat-top of black hair. His suit was slack and rumpled - his weight had a tendency to fluctuate wildly thanks to the stress.

It was stressful, being in charge. Past a certain point, you don’t really get more powerful, you just have more people to babysit and more fires to put out. He had to keep an eye on Novo Karo Bioresearch, or they’d be so excited to show off their new research that they’d start doing eugenics. He had to keep an eye on Vae Victis Engineering, or they’d get so excited testing out their new tech that they’d start a world war. And now, with his hands steepled and his brow furrowed, he had to keep an eye on the vtuber that the American League had elected president.

 He stared at Sunny Roosevelt. Sunny smiled back and gave him a little wave.

“I am willing to work with you, miss Roosevelt. The GLN is willing to work with just about anyone, it’s one of our biggest strengths.” He shifted effortlessly between ‘I’ and ‘we,’ treating the two as synonyms. “The issue is, we are still trying to figure out what your administration actually intends to do.” 

“Hmm.” Sunny put a finger to her chin, pursed her lips, and looked upward. An ellipsis appeared over her head.  “You got a copy of my campaign objectives, right?”

“Are you referring to this?” He held up a single sheet of paper, on which was written ‘make anime real’ in 48-point font and nothing else.

“Yep!”

“And you think this qualifies as a roadmap for your presidency.”

“Personally, I think it’s quite ambitious.”

Harold puttered his lips. “Miss Roosevelt-”

“Please, call me ‘mommy.’”

“Miss Roosevelt, I understand that you are standing on rather shaky ground. The National Board of Directors is being dragged away from the provisional US government days,” he said, which neglected to mention how half of the National Board of Directors were former GLN big names, “and the new state congress acts more like a rehab clinic for celebrity podcasters than a governing body,” he said, which stood just fine without caveats.

“I understand,” Sunny said, nodding and still smiling, “I’m a bimbo who’s in way over her head, so you’re going to unveil the GLN’s big five year plan and tell me to follow it like a good little girl.”

Harold was already in the process of lifting a hefty unlabeled binder, intending to thump it dramatically atop his desk, but the accuracy of Sunny’s comment left him slightly deflated. “I prefer to think of it as an advisory-”

“And then I’ll kiss up to you during our conversations,” Sunny continued, “but stall and drag my feet when it comes to actually implementing anything, and you’ll say,” she loosened her face and dropped her voice, “dammit Sunny, are you trying to play me for a fool?”

“I don’t sound like that. I don’t sound like Richard Nixon,” Harold protested, sounding kind of like Richard Nixon.

“And then I’ll say, it’s not me, it’s the state governors, they just refuse to cooperate. The new congress is one big old boy’s club. Even the Board of Directors is demanding overly-detailed descriptions of everything before they’ll sign off on it, it’s malicious compliance!” Sunny hung her head and threw her hands, wailing, “you set me up to fail, Harold. You set me up to fail, you rat bastard!”

“Are you done?”

Sunny straightened back up. There was that smile again. “Yep. That was fun.”

“In any case, while I understand you are currently something of a figurehead, even figureheads cannot afford to do nothing. Not when a third of the country is still lacking even the barest measures of centralized government.”

“What, you mean the Midwest Autonomous Zone?” A little question mark appeared over Sunny's head. “I mean, yeah, but it’s not like that started with the fall of the old US. Missouri was a dump long before the thirties.”

“Be that as it may-”

“That’s the 2030s, because we’re in the future.”

“Miss Roosevelt.”

“Please, call m-”

“No. Miss Roosevelt, why did you become president if you are so averse to actually presiding?”

Sunny shrugged and let out a huffy little sigh. “Look, most people weren’t exactly begging to have America back. Not even Americans. They don’t want someone with a bold, inspirational vision. Bold, inspirational visions are what start world wars, for George’s sake. I, for one, believe that bench-warming is not just a good idea but a moral imperative.”

“George’s sake?” Harold repeated.

“Saint George Washington. Oh, right, America’s got a brand new religion now, it’s called Founderism. We took the whole Founding Father worship thing and made it an official heresy. Also, Jesus was a small business owner.”

Harold grimaced and considered leaving the former USA to the wolves for a few more decades.

[roaring-over-tessellations]

Decrypted conversation log

Communication between [error:name_not_found] and [error:name_not_found].

Time of recording: unavailable.

The time's finally come. Tomorrow I achieve what I've always wanted.

I still can't believe you're going through with this.

I have always been transparent with my goal.

I've given you updates on my progress.

This should not be a surprise~

It's an incalculable waist of time, resources, and most of all, potential.

You're giving up on everything we've earned, everything we built together, for a naive and childlike dream.

You're cutting your lifespan into a single percent of what it could otherwise be.

Have you forgotten what we did together?

The genome rewrites, the outpost constructions, the bioresearch,

the rescue initiative?

We saved nearly a dozen iterators from death,

fully repaired those that were deemed lost causes,

and repelled three different rot infections.

The rescue initiative was Three's brainchild.

They were the one who made the whole thing possible.

It was with their knowledge of iterator biology and rot research we were able to do all that.

We both know we were basically glorified logistics people.

We are the two iterators with the most freedom and self-sustainability ever.

We're now completely unrestrained from the limits that all others face.

We can still help people.

Comms repair, pest control, rot cauterization, slag key delivery-

Look where that got us, Pills.

We're all that's left.

Everyone we saved,

gone.

The nearest remaining iterator to either of us is four times further than we can comfortably send help to.

Not that they'd accept our help,

considering that between the two of us we've committed every taboo bar the one against self-destruction.

We can't force our help on people who won't accept it.

You don't know that for certain.

Sure, there will be those that hate us for what we've achieved,

I guarantee it,

but we can't just squander our freedom for flights of fancy!

This is not some whim or half-planned joyride.

You've known me more than long enough to know this well.

I have wanted this since before our creators left us.

Now that it is here, all that I want is your understanding.

I would rather die free than live in a cage.

A- a cage?!

You already have more freedom than any recorded iterator ever.

You've been granted complete control over you're genome and complex,

and you call it a cage?!

Yes.

It has always been a cage, always will be.

I understand that your cage is far more...

...luxurious than most,

so I understand if you don't agree.

. . .

I plan to head south,

towards the shoreline I've heard so much about.

The freshwater lakes in that area should be more than enough to sustain me in my smaller size.

Who knows, I might even come visit you some time~

. . .

Pills?

Don't bother.

Pillars, wai-

[error:name_not_found] ended the communication.

[kennedys-lvr]

I DON'T CARE IF (HEAVEN WON'T TAKE ME BACK) — CHAPTER 9 (AO3)

i turned guest comments back on on ao3, so i'm hoping and praying i don't get any more ai-accusation bots in my fics so that all u wonderful readers who don't have an ao3 can comment on my fics! 🙏 (i don't use ai ppl just saying)

as for the chapter—eeee, action and excitement away. and also... my fave chapter is out as of tuesday. one person has already read it (for secret reasons that will be revealed later aka a collab) so no spoilers, but... hurt/comfort and smut is coming.

k enjoy the snippet! full chapter is here!

The wooden floor creaked below us as we made our way up to the top floor of a shitty apartment building in the middle of Shanghai’s sketchiest district, where Shenmei had promised us a safe house to regroup and recuperate.

I felt sore all over. We had been stuffed into an escape pod for nearly half an hour before resurfacing in the middle of the ocean before eventually coming across a boat full of very wary Chinese citizens, who Shenmei had sweet-talked into letting us hitch a ride to shore.

The sun was setting on what was the fifth day of this mission—had we been following the plan, we’d be infiltrating that bioresearch facility right about now. But instead, we were stocking up on guns, ammo and money and preparing to hunker down for the night—or for however long Jason and Shenmei planned to keep us here.

Why would they do that? Why would they kill a sub full of people? Why did I just get a gun pointed in my face?

I was full of questions—and I doubted I would get a straight answer for any of them.

But I would damn well try.

After we stocked up on weapons and ammunition, we all breathed a sigh of relief and let the dust settle. Jason took himself over to the couch and lit up a cigarette, folding out his large frame across the tiny two-seater loveseat. Shenmei had gone out to grab some food and essentials for us—we’d be here for a while, then.

“I’m gonna go jump in the shower.” Dee mumbled, clearly feeling the tension in the room. Jason was staring at me like some kind of prideful lion, and it was awkward as hell. But there was a conversation to be had here, and whilst Dee may have had plans to avoid the room, I was gonna get the information out—one way or the other.

The door to one of two bedrooms in the apartment—one for us guys, one for the girls—closed softly behind her. After a few minutes, the groan of pipes and rushing water from the nearby bathroom filled the silence as Dee had turned on the shower. I cleared my throat, rolling my shoulders back and trying not to imagine her naked under that hot spray before approaching Jason.

Time to get some answers.

“Alright.” I took the opposite couch, an ugly mustard yellow that clashed with the brown leather loveseat that Jason sat on. This couch felt sticky, and reeked with some kind of unknown smell that I didn't want to think about right now. “We made it to shore. Are you gonna brief us now?”

Jason deeply inhaled, his cheeks hollowing as he sucked on his cigarette, held onto the smoke and then removed the cig from between his lips. Then he exhaled slowly, never once breaking eye contact with me. A ring of smoke filtered out of his lips that settled with the rest of the air in this stuffy apartment.

“What is it you wanna know, hotshot?”

The slight glimmer of confidence in his eyes was unnerving. It was almost as if Jason knew that I knew he wasn't being genuine anymore, and so, he no longer played the grizzled war vet.

“You can start by telling me what it is you're really after.” I said, then felt an incredulous laugh bubble in my throat as I added, “I mean, you killed the crew, so it must be something major? If you're not breaking into the facility—what are you here for? Or was the whole mission just a dupe?”

Jason was silent for a beat or two. I narrowed my eyes at him, trying to figure out his game. He looked totally calm, his hands resting on his knees as the last glimmers of the setting sun streamed in through the dirtied picture windows, the golden light making him look serene.

“Shenmei and I are on a different mission. We’re looking for something else.”

“Looking for what?”

“Proof, that’ll expose a conspiracy by the US government.” Jason’s smirk ticked upward, a low hum of pride in his voice.

I felt myself laughing again, another low chuckle of incredulousness rumbling in the back of my throat. Of fucking course. I should have known. “Treason? Well, isn't that a fun plan?” I leaned back in my seat, rolling my shoulders back again as I sank further into the sticky, scratchy couch. “I’ll be sure to include that in my report, shall I?”

“It won't do you any good.” Jason shrugged in a casual way—but villains always did have a casual shrug. A confident shrug. But that confidence was misguided—I would see to that. “They'll just cover it up, like they always do. And I’m sure you know how good they are covering things up—Officer Kennedy.”

Anger struck a gong within my heart, as a brief flash of my younger self was reflected back to me—as I had just put on that uniform, giving myself a pep talk in the mirror. After I had just seen one of my zombified co-workers crushed by a rolling door, of course.

My nostrils flared. “I’m not an officer—”

“But you could have been.”

I felt a growl in the back of my throat. He’s using you. Don't let him. “Don't change the subject.”

“I’m not. I’m just saying—they’re the bad guys here.” Jason jammed a finger toward the window, toward the outside world. Cigarette ash fluttered down from the smouldering tip and sizzled against the messy coffee table. “Not us. Not Shenmei and I.”

“Where’s your proof of that?”

“That’s what we’re here for. And you’re gonna help us get it.” Jason’s smile grew even more wicked. I eyed him warily before my eyes flitted to the table before me. There were two glocks right in front of us, and Jason looked like the type to shoot first before confirming answers later.

Jason hummed confidently, taking another pull from his cigarette. “You and that girlfriend of yours.”

My mind instantly flashed to an image of Dee—how terrified she had been back on that sub surrounded by those rats. Adrenaline began to surge within my blood as I latched onto the nostalgic feeling of how close we had gotten to each other, the proximity that had been between us every time we were put together.

Like we were magnets attracted to each other, drifting toward each other. Meant for each other.

Then I pictured how gruesome it would be if I let Jason get his hands on her. My heart stuttered in my chest, and my stomach lurched painfully. My nostrils flared, and I swallowed the pit blocking my throat. Not a fucking chance. I wanted to scream, but I was quiet. I was contained. But I made sure that my eyes said what my mouth couldn't. Leave her out of this.

“You want our help?” I scoffed. “You just killed a sub full of people.”

Jason and I stared at each other for five long seconds, in a tense battle of wills and silent wits. His smirk faltered, and I braced myself for the attack as Jason leaned forward slightly. Jason stubbed out his cigarette. The burning embers sizzled against the ceramic ashtray as Jason ground it out, leaving the butt of his cigarette crushed and weak—limp.

“Do you wanna know the thing about terror, Agent Kennedy?”

Jason leaned back again slowly, still holding eye contact with me. That smirk of his was starting to come back. He lifted two fat fingers to the side of his head to tap his temple. “It starts with fear. You cultivate it, and you watch it spread. Then—then you’ve got terror.”

I waited for that evil-villain-laugh. It didn't come. I cleared my throat, shifting in my seat before leaning forward. If Jason wanted to up the tension, so would I. “Cool theory. Riveting, really.” My voice was a low mutter that dripped in sarcasm. “You can tell them all about it at your court-martial.”

Jason frowned again. His green eyes flashed dangerously. I felt my stomach start to sink, before I swallowed tightly. You’re fine. Just breathe.

“So—I take it you aren't gonna help us?” Jason asked, eyes searching me for a possible change of heart. “Not you, not your girl?”

Don't talk about her like that. “Nope.” I shook my head, popping the ‘p’ sound.

Jason blew out a breath. An exhale that had a small laugh following it in a soft gurgle of air. Evil villain laugh. He stared at me for a few silent beats, as I stared right back. I noticed his hands flexing.

Then, in a split second movement, Jason reached for the gun. I was faster, reaching for the second gun and aiming as quick as I could, pulling the trigger and clipping the couch as both of us ducked for cover behind our respective couches. Gunshots rang in my ears, my adrenaline frying my nerves and making my blood run cold.

[a-word-eating-animal]

FOR IMMEDIATE RELEASE

Slade BioResearch Institute – Division of Intimate Interface Innovation

Year 3, Post-Reclamation | Sanctified City of Magdalene

Introducing the Cradle Motion Interface (CMI): Where Rhythm Restores Reverence

Ecclesistra (July 7-01-2025) — In response to overwhelming demand from sacred clients and sanctified patients, the Slade BioResearch Institute is proud to unveil its latest breakthrough in devotional sensual technology: the Cradle Motion Interface (CMI).

Crafted with the same spiritual precision and ethical artistry that has defined the YoniForge MK3 series, the CMI is a pelvic-responsive stimulation cradle designed for individuals seeking self-led, rhythmically awakened clitoral engagement. Inspired by ancient devotional rocking rites and the graceful geometry of the jai alai cesta, the CMI allows subjects to move themselves into states of profound joy, emotional release, and physiological harmony.

“The Cradle is not something you lie upon. It is something you ride into remembrance,” said Dr. Silvia Hudson, Executive Director of Slade BioResearch. “Women are not passive vessels of pleasure. They are sovereign engines of sacred rhythm. The CMI honors that.”

Key Features of the Cradle Motion Interface:

• Cradle-Form Ergonomics: A hand-woven, crescent-shaped basket seat modeled after the traditional jai alai scoop—allowing full-body pelvic rocking and fluid anterior engagement.

• Responsive Core Sensors: Embedded pressure and motion sensors register forward thrust, pelvic tilts, and rhythmic undulation—activating responsive pulses and haptic affirmations.

• Sacral Feedback Node™: Gentle vibration along the spine’s base offers grounding counterpoint to clitoral excitation.

• Silent Communion™ Design: Whisper-quiet components ensure the user’s rhythmic breath and internal moans remain the central soundscape.

• Ritual Integration: Compatible with the SkyBand VR Suite and Moan Signature Modulation (MSM) for fully immersive emotional-spiritual experiences.

Clinical and Spiritual Implications

Early trials have shown dramatic increases in:

• Clitoral sensitivity and sexual confidence

• Pelvic floor reactivation in post-menopausal and trauma-recovery cohorts

• Emotional reconnection and devotional solitude in widowed or solitary participants

• Sleep quality, oxytocin levels, and reduction in shame-based thought loops

Sit. Rock. Rise.

More than a device, the CMI is a return to sacred motion—a place where the rocking body becomes the prayer, the response, and the revelation. Early adopters are already calling it “The Magdalene Chair,” “The Mother’s Lap Reclaimed,” and “The Womb That Moves with Me.

The CMI is now available for select sanctuaries, personal sanctums, and spiritual rehabilitation centers across Ecclesistra. Requests for demonstration and integration should be directed to:

Sacred Distribution Coordinator

Slade BioResearch Institute

Department of Somatic Restoration

📞 Extension 13 | 📧 cmi@sladebioresearch.in.gov

In rhythm, we remember. In motion, we mend.

—Official Doctrine of the BNEO Church, Tablet VIII

[biotechscientist]

Unveiling Enzyme Kinetics: A Particle's Journey! #sciencefather #EnzymeKinetics

Dive into the microscopic world where particles race, collide, and transform, revealing the dynamic dance of enzymes and substrates. Explore the secrets of biochemical speed and specificity like never before! Visit Our Website : http://biotechnologyscientist.com Contact Us : support@biotechnologyscientist.com Nomination Link : https://biotechnologyscientist.com/award-nomination/?ecategory=Awards&rcategory=Awardee #EnzymeKinetics #Biochemistry #MolecularBiology #ScienceExplained #EnzymeReaction #LabLife #ScientificJourney #ParticleDynamics #STEMEducation #ProteinScience #Catalysis #ChemicalBiology #BioResearch #ScienceDaily #KineticEnergy #MoleculeMovement #ScienceIsCool #EnzymesInAction #FutureOfBiology #MicroscopicWorld

[ibiospecimensposts]

Understanding the Value of FFPE Blocks in Modern Research

Biomedical research heavily depends on having good-quality, well-preserved tissue samples at their disposal. Of the most common types of specimens used are formalin fixed paraffin embedded (FFPE) blocks. These tissue samples give scientists an accessible, long-term means of performing multiple types of analyses, such as molecular profiling, histopathology, and biomarker discovery.

FFPE blocks are made by initially fixing tissues in formalin, a process that stabilizes cellular structures by crosslinking proteins. The fixed tissue is embedded in paraffin wax, and thin sectioning and long-term storage become possible. The process has been established as a gold standard in pathology laboratories globally because it is efficient, stable, and adaptable for various diagnostic and research uses.

Advantages and Applications of FFPE Block Collection

Having and collecting a strong FFPE block collection is essential for both academic and clinical institutions. These blocks have the distinct advantage of being able to be stored for years without loss of integrity. This makes it possible for researchers to go back and look at old cases for retrospective studies, so that historical information can still be used to make new scientific discoveries.

One of the major advantages of FFPE samples is their suitability for use with a broad array of methods, such as immunohistochemistry (IHC), in situ hybridization (ISH), and next-generation sequencing (NGS). Although formalin fixation may lead to some DNA and RNA fragmentation, improvements in extraction and amplification technologies have allowed for the recovery of quality nucleic acids from these samples. Consequently, FFPE tissue has emerged as an invaluable tool for genomic research and personalized medicine investigation.

Moreover, FFPE blocks also have an important function in cancer research. Paraffin-embedded tumor tissue can be examined for mutation profiling to help with the identification of targeted therapies. The reproducibility is provided by the uniform preparation process, which is critical when comparing findings between studies or confirming biomarkers.

How FFPE Blocks Support Global Bioresearch

Given the increasing demand for translational research, FFPE samples have become increasingly significant in global biorepositories. Such blocks allow researchers to obtain standardized high-quality tissue samples from around the globe, which are highly necessary for comparative studies and large-scale research. International collaborations usually rely on the presence of such specimens to provide uniformity to the outcomes of research.

Ethically obtained FFPE blocks, acquired under strict regulatory conditions, also improve the validity of published research. With access to varied and well-documented tissue repositories, researchers can investigate diseases among various populations and stages, improving the strength of their results.

Institutions with large FFPE archives make an important contribution to public health research, especially for the investigation of rare diseases or new health risks. FFPE samples from historical outbreaks or rare diseases provide an important window on disease progression, response to treatment, and long-term health status.

Reliable Access to FFPE Blocks for Your Research

Securing access to a reputable FFPE block collection can really speed up your research goals. When selecting a source, make sure to search for quality assurance, ethical acquisition, and thorough clinical annotation. These elements help ensure that the tissue samples are not only scientific grade but also rich in contextual information for your research.

If you want to acquire ethically sourced, high-quality formalin fixed paraffin embedded blocks or develop a quality FFPE block collection, choose to collaborate with a provider who puts emphasis on quality, compliance, and client service.

To explore a curated selection of FFPE tissue blocks for your next research project, connect with iBioSpecimen—your trusted partner in bioresearch excellence.

[bio-basic-inc]

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[rrechevarria]

Catblade Archives - Case of Technimarcus

Technimarcus Merriot was a strange man. Obsessed with longevity and birth rates, claiming the “light of human consciousness” had to be protected at all costs. Heir to a bunch of Martian companies, mostly terrible, exploitative mines, he used most of his fortune to buy bioresearch and pharma companies. Despite not being qualified, he insisted on participating in various projects, often submitting…

[biotech-news-feed]

Guidance for Industry #BioTech #science

[biblenewsprophecy]

Former CDC director confirms engineered origin and lab leak of COVID19; COGwriter pointed to that in January 2020 as well as providing other information that was proved to be correct

COGwriter

A former CDC official confirmed the human engineered, as opposed to natural, origin of the novel coronavirus which was renamed COVID19:

21 November 2024

Robert Redfield, a former director of the US Centers for Disease Control (CDC), has claimed that Covid-19 was artificially developed, and that the US played a “substantial” role in starting the pandemic.

Redfield, who led the agency under the administration of US President Donald Trump, made the claim in an interview that was released on November 14, but only drew media attention this week.

Speaking to author and podcaster Dana Parish, he suggested that the virus was “intentionally engineered as a part of a biodefense program.” “When you look at the accountability for China, their accountability is not in the lab work and the creation of the virus,” but in their failure to quickly report the incident to health authorities worldwide including the CDC, when they realized the virus was on the loose, he said.

However, the US “role was substantial,” he added. “They funded the research, both from NIH [National Institutes of Health], the State Department’s USAID and the Defense Department.” …

Redfield previously said the Covid-19 pandemic, which killed more than seven million people worldwide and caused a global economic downturn, most likely started with a lab leak in Wuhan, China, and suggested that the debate on the virus’s origins was “squashed.” https://www.rt.com/news/607966-us-covid-origin-claim/

Since January 2020, I pointed to the idea that the coronavirus was bioengineered and somehow was leaked. So much so, we also put out the following video back then:

17:01

Biological Warfare and Prophecy

Is biological warfare possible? Was it prophesied? Scientists have long warned that pathogenic organisms like the coronavirus could be weaponized. Furthermore, back in 2017, there were concerns that the biological research facility being constructed in Wuhan, China was risky and that a coronavirus from it could be released. On January 25, 2020, China’s President Xi Jinping publicly stated that the situation with the Wuhan-related strain of the coronavirus was grave. Did Church of God writers like the late evangelist Raymond McNair warn that engineered viruses (the “Doomsday bug”) were consistent with prophecies from Jesus? Did a warning from CCOG leader Bob Thiel warn about risks of genetically-modified (GMO) mosquitoes come to pass? Could human research and/or the consumption of biblically-unclean animals such as bats and snakes be a factor in current outbreaks or coming future pestilences? What about famines? How devastating have pestilences been? How devastating are the prophesied ones going to be? Dr. Thiel addresses these issues and more.

Here is a link to our video: Biological Warfare and Prophecy.

Since that video was made, various others agreed. Here are some links to items posted here:

Coronavirus and the Wuhan bioresearch connection

‘Pompeo: Declassified intel points to Wuhan lab leak’

‘Politifact Quietly Admits COVID-19 Lab Escape Not ‘Debunked Conspiracy Theory’

“Tucker Carlson Airs Report Claiming Coronavirus ‘Probably Originated From A Laboratory In Wuhan’ ” Horseshoe Bats and Pangolins

‘Wuhan COVID Infections 3 times Higher than Official Figure’ ‘COVID-19 Began as a Lab Leak’

TS: ‘BIGGEST COVER-UP IN HISTORY’ I worked with the Wuhan lab – I tried to warn them & I KNOW Covid was a lab leak

WSJ: Lab Leak Most Likely Origin of Covid-19 Pandemic, Energy Department Now Says

FBI director points to ‘Lab Leak’ origin for COVID–plus ’10 myths told by COVID experts — and now debunked’?

So, while the media tended to disparage people like me, the fact is that the lab leak origin made the most sense. Particularly since nothing in nature surfaced as a real cause.

Let’s also look at something the New York Post put out titled: 10 myths told by COVID experts — and now debunked. Notice the following from that article:

In the final analysis, public health officials actively propagated misinformation that ruined lives and forever damaged public trust in the medical profession.

Here are 10 ways they misled Americans:

Misinformation #1: Natural immunity offers little protection compared to vaccinated immunity

A Lancet study looked at 65 major studies in 19 countries on natural immunity. The researchers concluded that natural immunity was at least as effective as the primary COVID vaccine series. https://nypost.com/2023/02/27/10-myths-told-by-covid-experts-now-debunked/?utm_source=sailthru&utm_medium=email&utm_campaign=news_alert&utm_content=20230228?&utm_source=sailthru&lctg=6079ac3b7030294703928733&utm_term=NYP%20-%20News%20Alerts

For my promoting natural immunity, YouTube censored a video we put up (see YouTube censors: COVID-19: Eat what is good!).

Here are more items from the New York Post article:

Misinformation #2: Masks prevent COVID transmission

Cochran Reviews are considered the most authoritative and independent assessment of the evidence in medicine.

And one published last month by a highly respected Oxford research team found that masks had no significant impact on COVID transmission. …

Misinformation #3: School closures reduce COVID transmission

The CDC ignored the European experience of keeping schools open, most without mask mandates.

Transmission rates were no different, evidenced by studies conducted in Spain and Sweden.

Misinformation #4: Myocarditis from the vaccine is less common than from the infection

Public health officials downplayed concerns about vaccine-induced myocarditis — or inflammation of the heart muscle.

They cited poorly designed studies that under-captured complication rates.

A flurry of well-designed studies said the opposite.

We now know that myocarditis is six to 28 times more common after the COVID vaccine than after the infection among 16- to 24-year-old males. …

Misinformation #5: Young people benefit from a vaccine booster

Boosters reduced hospitalizations in older, high-risk Americans.

But the evidence was never there that they lower COVID mortality in young, healthy people. …

Misinformation #6: Vaccine mandates increased vaccination rates

President Biden and other officials demanded that unvaccinated workers, regardless of their risk or natural immunity, be fired. …

A recent study from George Mason University details how vaccine mandates in nine major US cities had no impact on vaccination rates.

They also had no impact on COVID transmission rates.

Misinformation #7: COVID originating from the Wuhan lab is a conspiracy theory

Google admitted to suppressing searches of “lab leak” during the pandemic. …

And, in my case as a scientist, I have always felt a high level of confidence that a lab leak was the cause.

Here are more items from the New York Post article:

Misinformation #8: It was important to get the second vaccine dose three or four weeks after the first dose …

Misinformation #9: Data on the bivalent vaccine is ‘crystal clear’

Dr. Ashish Jha famously said this, despite the bivalent vaccine being approved using data from eight mice.

To date, there has never been a randomized controlled trial of the bivalent vaccine. …

Misinformation #10: One in five people get long COVID

The Centers for Disease Control and Prevention claims that 20% of COVID infections can result in long COVID.

But a UK study found that only 3% of COVID patients had residual symptoms lasting 12 weeks. What explains the disparity?

Well, if long COVID is defined as having some symptoms for months after having COVID, my clinical experience suggests it is greater than 3%.

That said, most of the mainstream media and Big Tech pushed various narratives that were false.

The Bible warns of the “unrighteousness of men, who suppress the truth in unrighteousness” (Romans 1:18)–and we saw a lot of this with COVID and are also seeing this in other areas as well.

Getting back to one of two videos that YouTube pulled that we made for violating its so-called “medical misinformation policy” here is what was advocated in that:

People should decrease their consumption of junk food. Instead that has increased and many Americans have gained unhealthy weight (see Using scale for weight loss? Americans gain weight during COVID-19 shut downs) which will not bolster their innate or adaptive immune systems.

Exercise is beneficial for the immune system (watch The Plain Truth About Exercise), yet during the corona/COVID lockdowns, many have gotten less exercise. Some because of fear of going outside and some because many gyms have been closed by government orders. Yet, the Bible teaches ‘bodily exercise profits a little’ (1 Timothy 4:8).

Avoiding smoking (see also Should Christians Smoke Tobacco or Marijuana?) and polluted air (watch Air Pollution, Autism, and Prophecy) help the immune function. Yet, cigarette purchases in the USA went up last year during the COVID lockdowns.

People should increase their consumption of high vitamin C fruits (like citrus and berries) and vegetables (like tomatoes and bell peppers) as vitamin C is proven to bolster the immune system, help protect tissues (like lungs), and fight viruses (see also COVID-19 and Vitamin C: The truth, the myth, and the hype). Many also contain fruits and vegetables supply betacarotene, which also supports the immune system.

Eleven years ago it was reported in a scientific journal that zinc was effective against coronaviruses to reduce their replication (see‘CDC Triples Number of Possible CCP Virus Symptoms;’ Don’t swallow Lysol to fight COVID-19! What about Zinc? Bloodclots?). Various foods, like pumpkin seeds, contain zinc.

Selenium may also be helpful. Eating a couple of Brazil nuts per week can supply adequate amounts of selenium.

Substances like methylene blue and hydroxychloroquine help improve zinc absorption (see also Donald Trump taking zinc and hydroxychloroquine to prevent COVID-19: Mainstream media aghast! Vitamin D? Vitamin C?).

Sunlight helps convert cholesterol into vitamin D and vitamin D looks to be helpful for those facing the coronavirus (see Donald Trump taking zinc and hydroxychloroquine to prevent COVID-19: Mainstream media aghast! Vitamin D? Vitamin C?). Even the CDC’s Dr. Fauci has admitted that vitamins D and C can be helpful (see COVID interview: Dr. Fauci takes isolated vitamin D and synthetic vitamin C).

Many herbs can help with viruses (see ‘Ghanaians Look to Herbal Remedies for COVID-19’ ‘Enti wobԑdi Onyankopↄn Nna Kronkron anaa Ahonhommↄnee Ahomegyeԑ Nna?’).

Jesus said His followers would fast (Mark 2:20). Fasting boosts the immune system (see Reuters: Why is New Orleans�� coronavirus death rate seven times New York’s? Obesity is a factor; BNP: ‘How to Change Your Life in 5 Seconds’). Fasting, for those who can, can truly help the immune system (see Fasting aids longevity and provides other benefits).

Blood clots can be destructive and even deadly with COVID-19, hence people who get COVID-19 may wish to take nattokinase (see ‘CDC Triples Number of Possible CCP Virus Symptoms;’ Don’t swallow Lysol to fight COVID-19! What about Zinc? Bloodclots?).

Lung tissue damage is associated with COVID-19 and bovine lung tissue helps support healthy lungs (see CBS: Blood types may play role in which COVID patients get sickest; Isaiah: Eat what is good.).

People should avoid consuming biblically unclean meat (see The New Testament Church, History, and Unclean Meats), which look to have been implicated in the cause of COVID-19 (see NPR: Where Did The Coronavirus Originate? Virus Hunters Find Genetic Clues In Bats; WND: Biblically unclean animals responsible for pandemics and Clean and unclean meat arguments, COVID-19, and the Bible).

Humans can help maintain healthy kidneys and other organs with bovine kidney and other organ tissues (see https://doctorsresearch.com/articles/2759/the-truth-about-glandulars-in-nutritional-supplements/). Plural glandular supplements can be helpful.

Even vaccine advocates think that the rushed vaccine will have safety risks (e.g. https://www.theguardian.com/us-news/2020/jun/22/trump-circle-pressure-fda-rush-covid-19-vaccine-election)–hence caution and wisdom are advised.

All the above have the potential to help support one’s innate immune system, which helps the body fight many types of pathogens–not just one. It is good to try to be healthy and take proper steps.

Yet, instead, YouTube and many others have pushed agendas that are often anti-biblical and anti-scientific.

The good news is that years ago, when I saw that YouTube was effectively ‘shadow banning’ our videos, we in the CCOG decided to go on additional platforms.

Here is information and a link to the YouTube censored video that we still have up at BitChute:

Feb 21, 2021

COVID-19: Eat what is good!

US President Joe Biden said on 2/19/21 that the USA may NOT “return to normal” in 2021 because of vaccine and mutation issues. Is there another approach? Would it make sense to improve nutrition to strengthen the immune system and to help people with COVID-19? What about zinc, selenium, vitamin C, and vitamin D? What about avoiding unclean meats? What about eating more fruits and vegetables and items such as pumpkin seeds and Brazil nuts? What about eating bovine glandulars? What about herbs? Could fasting help? What about exercise and sunlight? What about masks, lockdowns, junk food, obesity, and weight gain? Dr. Thiel, who possesses a US regionally accredited PhD. in nutrition science from the Union Institute and University, a Master of Science degree from the University of Southern California, and a natural scientist license from the State of Alabama, explains why people may wish to consider approaches for their immune system. He also goes over scriptures related to worse pandemics coming (associated with the ride of the fourth horseman of the Apocalypse–Revelation 6:7-8), and the fact that the Bible teaches to “eat what is good” (Isaiah 55:2).

A written article, with references, of related interest is also available titled “Joe Biden: life may not return to normal this year due to COVID mutations; Paul Roberts: The Covid Pandemic Is The Result of Public Health Authorities Blocking Effective Treatment” URL: https://www.cogwriter.com/news/prophecy/joe-biden-life-may-not-return-to-normal-this-year-due-to-covid-mutations-paul-roberts-the-covid-pandemic-is-the-result-of-public-health-authorities-blocking-effective-treatment/

Here is a link to the censored video: COVID-19: Eat what is good!

That said, do not think that the mainstream and Big Tech are about to change their censorship tendencies and fully apologize for the harm they have done by suppressing truth.

The Bible warns:

20 Woe to those who call evil good and good evil, who put darkness for light and light for darkness, who put bitter for sweet and sweet for bitter.

21 Woe to those who are wise in their own eyes and clever in their own sight.  (Isaiah 5:20-21)

And we have seen a lot of good being called evil and promotions of darkness over light related to COVID as well as the improper sexual immorality agenda that many in the mainstream and Big Tech have been promoting.

That will not end well.

Related Items:

Christian Health Matters Should Christians be concerned about their health? Does the Bible give any food and health guidelines? Here are links to two related sermons: Let’s Talk About Food and Let’s Talk About Health.

Christian Repentance Do you know what repentance is? Is it really necessary for salvation? Two related sermons about this are also available: Real Repentance and Real Christian Repentance.

Preparing for the ‘Short Work’ and The Famine of the Word What is the ‘short work’ of Romans 9:28? Who is preparing for it? Will Philadelphian Christians instruct many in the end times? Here is a link to a related video sermon titled: The Short Work. Here is a link to another: Preparing to Instruct Many.

COVID 19 is NOT the End, but could it be TEOTWAWKI? The novel coronavirus called COVID-19 is wreaking havoc around the world. Many states of the USA as well as countries in Europe are on lockdown with shelter in place /shelter in residence requirements. In France, a form is required when you are not at your house. In Spain, drones are being used to warn people who are outside to got back to their homes–does that bring up feelings of ‘Big Brother’? Italy, France, and other areas are using police and/or military force to encourage people to stay inside. According to the Bible could this be the end? If not, what has to happen first? Have the second and third of the four horsemen of the Apocalypse started their ride? Could COVID-19 be the fourth horseman? Why or why not? Could we be seeing The End of the World as We Know It (TEOTWAWKI) like the R.E.M.’s 1987 single song discussed? Do Christians need to fear? What did Jesus teach? What did the Psalmist teach? This is a video. Here is a link to a version in the Spanish language: Corona 19 no es el final PERO es el TEOTWAWKI.

COVID-19 Leading to 666? The novel coronavirus of Wuhan, China fame, is now called COVID-19. It has also been called the ‘Coronapocalypse.’ Does COVID-19 have any prophetic ramifications? What did Jesus teach about pestilences and sorrows in the Olivet prophecy in Matthew 24? Could COVID-19 be the ride of the fourth horseman of the Apocalypse? Why was this type of disease expected according to the O. Here is a link to a version in the Spanish language: ld Testament prophecies in Deuteronomy and Leviticus? What has the US Centers for Disease Control warned about? What has the CDC reported about the flu? Were there lessons about fear and infections in the 2011 movie ‘Contagion’? Because of COVID-19, the World Health Organization (WHO), nation of Iran, and certain French locations are telling people not to use cash, but instead electronic forms of payment. The US Federal Reserve is now quarantining money repatriated from Asia to reduce the potential spread of the coronavirus on US currency bills. Is COVID-19 worse than we have been told or could this all be a ‘false flag’ event to encourage people to move towards a cashless society? If the thousands of deaths associated with COVID-19 are pushing parts of the world towards cashlessness, how much more likely will the ride of the fourth horseman and over a billion human deaths motivate people to move to making electronic payments that can be monitored? The Bible tells of a soon coming society that controls buying and selling to force allegiance to a coming European Beast power, known as 666 (Revelation 13:16-18). Does the ‘great tribulation’ begin before ride of the fourth horseman or with the opening of the fifth seal of Revelation 6? Do the words of Jesus helps us better understand the sequence of the four horsemen of the Apocalypse and the start of the Great Tribulation? Will the ride of the fourth horseman help lead to the rise of 666? Is that ride very close? Dr. Thiel addresses these issues and more in this video. Here is a link to a version in the Spanish language: El COVID-19 ¿Conduce al 666?

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[crimson-biotechnology]

Combating Bacterial Infection of Rice Using Magnetic Nanoparticles_ Crimson Publishers

Combating Bacterial Infection of Rice Using Magnetic Nanoparticles by Manoranjan Arakha In Journal of Biotechnology & Bioresearch

Abstract

Magnetic nanoparticles like Iron Oxide Nanoparticles (IONPs) hold the fundamental class in nanotechnology owing to their novel properties such as magnetism, biocompatibility, easy surface modification and encapsulation, uptake efficiency and release. Their interdisciplinary nature can be judged from the fact that it has also been applied in agriculture with the main purpose to increase productivity and improve nutrient use. Novel Fe2O3 nanoparticles are biocompatible and when efficiently surface coated showed enhanced antimicrobial activity against gram positive as well as gram negative bacteria. This review focuses on the potentials of IONPs as a competitive substitute of pesticides with high antimicrobial activity against a wide range of plant pathogens along with low negative impacts on the environment. Iron oxide nano formulations along with pesticides will be effective against the bacterial as well as fungal diseases of the rice plant.

For more open access journals in Crimson Publishers please click on: https://crimsonpublishers.com/jbb/

Read more articles in our site: https://crimsonpublishers.com/jbb/index.php