#NecrotizingFasciitis

[omanxl1]

This Is How We Get Down! (Part Five)

This is how we get down on this Saturday afternoon but the science dropped is appropriate for any time frame;  bear witness to how we put it down like this! Digital Crate Digging Continues usually accompanied by this good word; check us out as we bring insight like this! How will we get down? it’s a silhouetted hello live and direct from behind the scenes of the ongoing smoke and…

[taimoorkhan]

Title: Necrotizing Fasciitis: An In-Depth Exploration of Pathogenesis, Clinical Presentation, Diagnosis, and Therapeutic Approaches

Introduction:

Necrotizing fasciitis, commonly referred to as the "flesh-eating disease," stands as a formidable entity within the realm of infectious diseases. This comprehensive discourse delves into the intricacies of its pathogenesis, clinical presentation, diagnostic nuances, and the evolving therapeutic strategies employed to combat this insidious affliction.

I. Pathogenesis: Deciphering the Intricacies

The origins of necrotizing fasciitis lay in the complex interplay of bacterial virulence factors and host immune response. The inciting events often involve polymicrobial or monomicrobial infiltration of subcutaneous tissues. Bacteria such as Streptococcus pyogenes secrete destructive enzymes, including hyaluronidases and proteases, which facilitate tissue degradation. The ischemic environment resulting from these processes allows anaerobic bacteria to thrive, further compounding the tissue devastation. Notably, the proclivity of Group A Streptococcus to exploit immunological naivety reinforces its virulence, rendering this organism a significant pathogenic protagonist.

II. Clinical Presentation: A Spectrum of Manifestations

The clinical portrait of necrotizing fasciitis is marked by a complex spectrum of manifestations. The initial mimicry of cellulitis gradually unfolds into a constellation of symptoms including fever, tachycardia, and disproportionate pain. Erythema rapidly escalates, often betraying the underlying seriousness of the condition. Notably, the presence of cutaneous anesthesia serves as a characteristic hallmark. Inspection of the skin reveals a transition from edema to a glossy, tense, and darkened appearance – an ominous harbinger of impending necrosis. This transformation is accompanied by the palpable wooden-hard consistency of subcutaneous tissue, often coupled with crepitus due to gas accumulation.

III. Diagnosis: A Precarious Balance

Diagnostic strategies for necrotizing fasciitis embrace a multi-faceted approach. Blood cultures are pivotal, as they often reveal the microbial culprit, with Streptococcus pyogenes occupying a predominant role. Elevated C-reactive protein levels and coagulation profiles serve as indices of the systemic inflammatory response. Radiological imaging, namely X-ray, computed tomography (CT), and magnetic resonance imaging (MRI), serve to visualize subcutaneous emphysema and ascertain the extent of tissue involvement. Biopsy augments diagnostic precision, enabling differentiation from conditions such as cellulitis.

Recent advancements have introduced point-of-care ultrasound (POCUS) as a pivotal adjunct in the diagnostic armamentarium for necrotizing fasciitis. POCUS, often wielded by skilled practitioners at the bedside, engenders real-time visualization of tissue planes, facilitating early detection and accurate assessment of disease extent. This non-invasive modality offers remarkable precision, enabling differentiation between superficial cellulitis and the deeper involvement characteristic of necrotizing fasciitis. Moreover, POCUS aids in discerning subcutaneous emphysema, a cardinal feature of gas-forming infections. By appraising the subcutaneous tissue architecture, POCUS mitigates the diagnostic challenge posed by cutaneous anesthesia, substantiating the clinical diagnosis with objective imaging evidence. The integration of POCUS augments diagnostic confidence, expediting prompt therapeutic intervention and potentially mitigating disease progression. As POCUS continues to be harnessed in clinical practice, its utility as a veritable extension of the clinician's diagnostic acumen underscores the ongoing evolution of diagnostic paradigms in the realm of necrotizing fasciitis.

IV. Therapeutic Approaches: Navigating the Complex Landscape

The management of necrotizing fasciitis necessitates a multidisciplinary approach encompassing resuscitation, surgical intervention, and pharmacotherapy. Swift resuscitation addresses hemodynamic instability, aiming to restore tissue perfusion. Surgical debridement remains the cornerstone of intervention, seeking to halt disease progression and remove necrotic tissue. The pharmacological arsenal integrates clindamycin or lincomycin to counteract streptococcal exotoxins, supplemented by broad-spectrum antimicrobials targeting polymicrobial involvement. Meropenem emerges as a preferred choice due to its expansive coverage, while clindamycin synergizes by mitigating toxin production.

V. Current Research and Future Horizons: Hyperbaric Oxygen and Immunotherapy

The role of hyperbaric oxygen therapy and intravenous immunoglobulin (IVIG) in necrotizing fasciitis management remains subjects of ongoing investigation. Hyperbaric oxygen demonstrates potential benefits in select cases, particularly those involving anaerobic pathogens. IVIG, administered during the early phase, potentially mitigates the exuberant inflammatory response observed in necrotizing fasciitis associated with Group A Streptococcus.

Conclusion:

Necrotizing fasciitis, a complex amalgamation of microbial virulence and host immunology, continues to intrigue and challenge medical practitioners. This compendium illustrates its multifaceted dimensions, bridging the chasm between pathogenesis, clinical presentation, diagnosis, and evolving therapeutic modalities. As medical science evolves, the collective pursuit of unravelling this clinical enigma persists, exemplifying the symbiotic convergence of scientific advancement and clinical application. The saga of necrotizing fasciitis continues to underscore the indomitable spirit of human endeavor against the backdrop of microbial persistence.

[drmilindcom]

Ayurvedic Remedies for Flesh-Eating Bacteria: Nature’s Defence Against a Menacing Threat

[cornpone]

[iamrichmothy]

[Comedy / True Crime / Society & Culture] Eerie Education | Episode 1 - Our Very First Episode!

Website // Spotify

Twitter // Facebook // Instagram

This week is our very first episode! Today we discuss the mysterious case of Brandon Swanson, the first female serial killer of Italy, Leonarda Young and discuss the crippling disease, Necrotizing fasciitis.

We are two Yorkshire folk and an American who enjoy researching and talking about true crime and other strange/creepy things!

[physio4themind]

#climatechange has bothered me before i had my daughter and son i actually wasnt going to have children my daughter is 28 my son 23 they are the blessings. I am glad i changed my mind but i am saddened that the earth is in this state. But i have been concerned since i was 13 am 46 now 47 in nov. I support the generation standing up we should be proud I AM PROUD TO BE A #GLOBALCITIZEN PARTOF THE #TREECHARTER WILL spread the message as much as i can for no discrimination. To stop hate in all form, to stand together with people who r different because i am different and i am proud of that i went vegetarian at 13. Lets lead strong lets lead to make a diffrance lets stand together lets grow in strength. Together we can i cant always go to marches so lets spread a march on hear. We all have to try to help are beautifful mother home. Blessed be. #forthefuture #climatechange #LGBTQ #8secondstobenice #enchantedrealms+indivisiblereal #globalcitizen #TREECHARTER #necrotizingfasciitis #p.t.s.d #mentalhealthawarness #suicideawarness #mind #suicidewatch LETS DO R BIT. XXX https://www.instagram.com/p/B2xLTXiHLbZ/?igshid=1esvwn9f919m2

[doyouthatknow]

What is Necrotizing Fasciitis?

Necrotizing fasciitis (NF) is an infection that affects the fascia and leads to rapidly spreading tissue death and rapidly spreading to include adjacent soft tissue. It is also called meat-eating disease (bacteria). Several different types of meat-eating bacteria can cause life-threatening conditions that affect both healthy and individuals with underlying medical problems. Although rare, there has been an increase in the incidence of necrotizing fasciitis in the last decade. Although probably not adequately reported, the annual incidence of necrotizing fasciitis is estimated to be approximately 500-1,000 cases per year with a prevalence of 0.40 cases per 100,000 populations per year. Early diagnosis and emergency treatment of necrotizing fasciitis is critical to managing the potentially devastating consequences of this medical emergency. What is the history of necrotizing fasciitis? One of the first definitions of necrotizing fasciitis was the diagnosis of erysipelas. It came from Hippocrates in the 5th century. Although necrotizing fasciitis has existed for centuries, more detailed explanations of this condition have been reported in the early 19th and early 20th centuries. In 1952, B. Wilson first used the term necrotizing fasciitis to describe this condition, and it remained the term most commonly used in modern medicine. Other terms used to describe this same condition include meat-eating bacterial syndrome, necrotizing soft tissue infection, suppurative fasciitis, dermal gangrene, streptococcal gangrene, hospital gangrene, necrotizing cellulitis, Melener's ulcer and Melener's gangrene. When necrotizing fasciitis affects the genital area, it is often referred to as Fournier's gangrene. What Causes and Risk Factors of Necrotizing Fasciitis?

Most cases of necrotizing fasciitis are caused by bacteria, but fungi can rarely cause it. Most cases of necrotizing fasciitis originate from group A beta-hemolytic streptococci, but many bacteria may be isolated and associated with other bacterial pathogens. Group A is the same bacterium responsible for streptococci, strep throat, impetigo (skin infection) and rheumatic fever. In recent years, there has been an increase in intravenous drug addicts in cases of necrotizing fasciitis caused by community-acquired methicillin-resistant Staphylococcus aureus (MRSA). Most cases of necrotizing fasciitis are polymicrobial and include both aerobic and anaerobic bacteria. Additional bacterial organisms that may be isolated in cases of necrotizing fasciitis include Escherichia coli, Klebsiella, Pseudomonas, Proteus, Vibrio, Most cases of necrotizing fasciitis have a previous history of trauma, such as cuts, abrasions, insect bites, burns or needle sores. These lesions may initially appear insignificant or small. Surgical incision sites and various surgical procedures may also serve as a source of infection. In most cases, however, there is no obvious source of infection or entry portal to explain the cause. https://www.orak11.com/index.php/how-to-make-money-from-home/ Once the bacterial pathogen has gained entry, the infection can spread from subcutaneous tissues to involve deeper facial planes. Infection spreads progressively rapidly, sometimes involving adjacent soft tissues, including muscle, fat and skin. Various bacterial enzymes and toxins cause vascular obstruction, resulting in tissue hypoxia and tissue necrosis. In most cases, these tissue conditions allow the proliferation of anaerobic bacteria, allowing the progressive spread of infection and the continued destruction of tissue. There is also a risk of developing necrotizing fasciitis in people with underlying medical problems and a weak immune system. Various medical conditions such as diabetes, renal failure, liver disease, cancer, peripheral vascular disease and HIV infection are frequently present in patients who develop necrotizing fasciitis, such as those receiving chemotherapy. In addition, patients undergoing organ transplants and receiving corticosteroids for various reasons, alcoholics and drug addicts are at risk. However, most cases of necrotizing fasciitis occur in a healthy individual and in healthy cases without predisposing factors. For classification purposes, necrotizing fasciitis is divided into three groups, primarily based on the microbiology of the underlying infection. Type 1 NF is caused by multiple bacterial species (polymicrobial), type 2 NF is caused by a single bacterial species (monomicrobial), typically Streptococcus pyogenes; type 3 NF (gas gangrene) is caused by Clostridium spp, type 4 NF is caused by fungal infections, particularly Candida spp. And infection caused by Zygomycetes Vibrio spp. (Often Vibrio vulnificus) is a variable form that is frequently seen in people with liver disease. It usually occurs after eating seafood or exposing skin wounds to sea water contaminated by this organism.

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Is Necrotizing Fasciitis Infectious?

Necrotizing fasciitis is not considered an infectious disease. However, it is theoretically possible that an individual is infected with the same organism, for example an MRSA infection, which causes necrotizing fasciitis in a person in direct contact with them. Although it is possible for the exposed individual to continue to develop necrotizing fasciitis, it is very rare and unlikely. What are the symptoms? Symptoms of necrotizing fasciitis vary according to the degree and progression of the disease. Necrotizing fasciitis usually affects the extremity or genital area, although it is in any part of the body. During the course of the disease, patients with necrotizing fasciitis may initially look deceptively good and may not show any superficial signs of an underlying infection. Some people may complain of pain similar to the muscle initially taken. However, as the infection spreads rapidly, symptoms of serious illness become apparent. Necrotizing fasciitis usually appears as a localized area of ​​redness, warmth, swelling and pain that resembles a superficial skin infection. Often, patients' pain and tenderness are not commensurate with visible signs of the skin. There may be fever and chills. The skin's redness spreads rapidly over hours and the skin can be dark, purplish or dark. Overlapping blisters, necrotic siblings (black shells), skin hardening, skin deterioration and wound drainage may develop. Sometimes a subtle crackling sensation can be felt in the tissues under the skin. Severe pain and tenderness may be reduced due to subsequent nerve damage and may lead to localized anesthesia of the affected area. If left untreated, infection continues to spread and generalized physical detention, it can often lead to sepsis and often death. Other symptoms associated with necrotizing fasciitis may include malaise, nausea, vomiting, weakness, dizziness, and confusion. When to seek medical help? Immediate identification and treatment of necrotizing fasciitis is critical to increase the likelihood of a positive outcome. Due to the rapid progression of this condition, detailed screening and early diagnosis are required to initiate immediate treatment immediately. Individuals with underlying medical problems or a weak immune system should be particularly vigilant. If any of the following symptoms occur, a healthcare professional should be consulted:  • An unexplained skin rash, temperature, tenderness or swelling area with or without a history of skin trauma •  Changes in skin color or skin texture  • Drain from an open wound  • Fever or chills • Intense pain or discomfort of the body area that has previously been traumatized or not traumatized  If a person has previously been evaluated by a healthcare professional and the above symptoms have progressed or the person cannot recover, an antibiotic treatment at home should be re-evaluated immediately. If necrotizing fasciitis is suspected, an accelerated surgical consultation is needed. Tests and Inspection

Diagnosis of necrotizing fasciitis is usually predicted initially based on the patient's history and physical examination findings. Although there are several laboratory tests and imaging studies that can help make the diagnosis, immediate results may not be immediately available. Therefore, in any patient with signs or symptoms suggestive of necrotizing fasciitis, a high index of suspicion should be promptly discussed with a surgeon to accelerate management. The tests are as follows:  • Laboratory tests: include various blood tests, such as a complete blood count, which may reveal an elevated number of white blood cells. Electrolyte panels, blood cultures and other blood tests are also generally obtained. However, the results of these blood tests cannot be used solely for an immediate diagnosis. • Imaging studies such as CT scan, MRI and ultrasound: These imaging studies have been used successfully to identify cases of necrotizing fasciitis. It can be used when symptoms are equivalent or when the diagnosis is suspicious. These methods can help determine the degree of infection, as well as identify fluid areas, inflammation, and gas fields within the soft tissue. Although occasional plain radiographs may show gas in soft tissue, they are considered less useful and less valuable. Imaging studies in cases suggesting necrotizing fasciitis should not delay the definitive treatment.  • Tissue culture, tissue biopsy and gram staining results: It can help to accurately identify the organisms responsible for infection, and this can help guide appropriate antibiotic therapy. Are There Home Remedies for Necrotizing Fasciitis? • Necrotizing fasciitis is an emergency that cannot be managed at home.  • Patients with necrotizing fasciitis require hospital admission, appropriate IV antibiotics, surgical debridement, and close observation in the intensive care unit. What are Necrotizing Fasciitis Treatments? • When the diagnosis of necrotizing fasciitis is suspected or confirmed, urgent measures should be taken to promptly intervene treatment to reduce Necrotizing analytes. Medical treatment of necrotizing fasciitis mainly involves the use of much less used antibiotics, hyperbaric oxygen therapy and intravenous immunoglobulin. Definitive treatment for necrotizing fasciitis ultimately requires surgical intervention.  • Initial treatment includes patient stabilization, including additional oxygen, cardiac monitoring, and intravenous fluid delivery.  • Some patients with sepsis may require the administration of intravenous medications to increase blood pressure and require a breathing tube in case of serious illness or respiratory failure.  • Intensive care requires close monitoring and supportive care. Antibiotics of Necrotizing Fasciitis • Broad-spectrum antibiotics should be started immediately. Since responsible organisms are not initially known, antibiotics should cover a wide variety of organisms including aerobic gram-positive and gram-negative bacteria, as well as anaerobes. Consideration of infection caused by MRSA should also be considered.  • There are various antibiotic regimens that may include monotherapy or multidrug regimens. Commonly recommended antibiotics include penicillin, ampicillin-sulbactam, clindamycin, aminoglycosides, metronidazole, carbapenems, vancomycin and linezolid. Most clinicians treat multiple IV antibiotics because bacteria that cause necrotizing fasciitis are usually resistant to more than one antibiotic and some infections are caused by more than one bacterial species. • Antibiotic coverage can be adjusted when culture results, causative organisms, organisms are identified and antibiotic susceptibility results are found. Antibiotic susceptibility testing is required to properly treat MRSA and new NDM-1 antibiotic-resistant bacteria species. https://www.orak11.com/index.php/balance-diet-plan/ Hyperbaric Oxygen Therapy (HBO) This therapy gives patients in a special room a high concentration of oxygen, thereby increasing tissue oxygenation. This inhibits anaerobic bacteria and promotes tissue healing. Some researchers believe that HBO reduces mortality in some patients when combined with an aggressive treatment regimen including surgery and antibiotics. HBO is not commonly available, so consultation with a hyperbaric specialist may be necessary. However, this should not delay definitive surgical treatment. Intravenous Immunoglobulin (IVIG) Some investigators believe that IVIG may be a useful adjunctive treatment in some cases of streptococcal necrotizing fasciitis, as it has been shown to successfully neutralize streptococcal ecotoxins in Streptococcal toxic shock syndrome. However, its use in necrotizing fasciitis is controversial and is therefore not considered a standard of care. Surgical intervention Rapid surgical debridement of infected tissue is the cornerstone of treatment in cases of necrotizing fasciitis. Early diagnosis and emergency surgery have been shown to reduce morbidity and mortality, which emphasize the importance of early surgical involvement and consultation. Comprehensive surgical debridement is required in all necrotic tissues. Infected all tissues, fascia, muscle, skin and so on. Large and deep incisions may be required to excise until healthy, viable tissue appears. Repeated surgical debridement is required between the following hours and days after the first surgical intervention, because the progression of the disease may not be sudden, severe and stubborn. Sepsis may lead to other sites of infection, and surgical intervention may be required in these areas, which may also require some patients to require amputation. In some cases, despite repeated surgical debridement, Follow-up After Treatment Patients recovering from necrotizing fasciitis usually require follow-up with various specialists depending on the complications encountered during hospital stay and subsequent outcomes. Many patients require physical therapy and rehabilitation with skin graft and reconstructive surgery. Sometimes psychological intervention is required for some patients who may experience depression, anxiety, or other psychological repercussions. Disease Prevention

Preventive measures may be taken to reduce the likelihood of necrotizing fasciitis, however, not all cases may be completely preventable, as the underlying cause is usually not identified. Since many cases start after some kind of skin trauma, proper wound care and treatment are important. All wounds should be kept clean and any signs of infection should be observed. Early detection and treatment of infection may be the best measure to prevent necrotizing of this disease. If any signs of infection occur, seek medical attention immediately. Patients with underlying medical problems, such as diabetes, should pay attention to any signs of infection, and people with weakened immune systems should take precautions to avoid exposure to potential infections. For people with liver disease it is recommended to avoid seafood and direct contact with hot sea water potentially contaminated with Vibrio species. People with active skin infections or open wounds should be avoided in jacuzzis, swimming pools and natural water sources. Good personal hygiene and frequent handwashing can prevent infection and control the spread of infection. Compliance with the appropriate sterile surgical technical rules and gloves, gowns, masks, etc. in hospitals. strict barrier measures should be observed. And the implementation of isolation measures may also prevent health personnel from preventing the development and spread of infection. What is the Prognosis of Necrotizing Fasciitis? Prognosis for patients with necrotizing fasciitis depends on many factors such as patient age, underlying medical problems, causal organisms, the extent of infection, and the duration of diagnosis and onset of treatment. Early diagnosis and aggressive surgery and medical treatment are the most important factors in determining the outcome. Necrotizing fasciitis is a life and limb threatening condition with poor prognosis if left untreated. Complications and potential outcomes may include limb loss, scarring, deformity and disability, while many patients continue to develop sepsis, multiple system organ failure and death. Disease rates are as follows:  • Combined morbidity and mortality rates have been reported to range from 70% to 80%.  • Mortality rates in the scientific literature range from 8.7% to 76%. • The mortality rate for untreated necrotizing fasciitis approaches approximately 100%. https://www.orak11.com/index.php/hair-follicle-infection-folliculitis-and-treatment/ References: cdc.gov sepsis.org drugs.com Read the full article

[aeysheajones]

#Watercolour of #necrotizingfasciitis under the microscope #boutiqueofthekitschandstrange #art #scienceandart #science #paintersgunnapaint #painting

[sickstayhome]

Today is #necrotizingfasciitisawarenessday Bringing #awareness to #necrotizingfasciitis . . . . #sickstayhome #sick #coldandflu #coveryourmouth #washyourhands #health #etiquette #bookstagram #book #comingsoon

[thunderwishes]

I am probably going to get a lot of creeps for this post (I will keep them to myself) but I feel like I have been holding back on Shelby love lately. It’s been. Year since I have gotten this tattoo, I still love it as much. I want to add blue and purple feathers to it. #amputee #amputeegirl #amputeelife #disabled #crohnsgirl #crohnslife #necrotizingfasciitis #tattoo #tattoos #tattooedgirls #tattooedamputee

[laocommunity]

How One Man Survived a Flesh-Eating Illness and What You Need to Know to Stay Safe

How One Man Survived a Flesh-Eating Illness and What You Need to Know to Stay Safe How One Man Survived a Flesh-Eating Illness and What You Need to Know to Stay Safe When Jason McClellan of Michigan noticed a small red bump on his leg, he thought it was nothing more than a spider bite. However, within days, the bump had grown into a massive wound that continued to deteriorate despite antibiotics. Eventually, McClellan learned that he had contracted a flesh-eating bacterial infection called necrotizing fasciitis. He underwent a series of surgeries and months of intense rehabilitation to survive. McClellan's case was a rare and extreme example of the dangers of skin infections. But it serves as a reminder that even seemingly minor skin conditions can quickly spiral out of control without proper attention. Here's what you need to know to stay safe: What is Necrotizing Fasciitis? Necrotizing fasciitis is a rare but deadly bacterial infection that can quickly destroy muscles, skin, and tissue. It typically begins as a small cut or scrape and can be spread through contact with contaminated water or soil. Early symptoms may include fever, chills, and pain in the affected area. As the infection progresses, the skin may turn red and blister, and large areas of tissue may begin to die off. In some cases, the infection can spread rapidly throughout the body and cause sepsis, which can lead to organ failure and death. #necrotizingfasciitis #flesheatinginfection #bacterialinfection How to Prevent It The best way to prevent necrotizing fasciitis is to practice good hygiene and avoid contact with contaminated water or soil. Make sure to wash your hands regularly and keep any wounds or cuts clean and covered. Avoid swimming or soaking in untreated water, especially in warm, stagnant areas. If you have an underlying condition that weakens your immune system, it's important to take extra precautions to avoid skin infections. #skincare #prevention #hygiene When to Seek Medical Attention If you notice any signs of a skin infection, it's important to seek medical attention as soon as possible. Early treatment with antibiotics or surgery can help prevent the infection from spreading and causing serious damage. Pay attention to any changes in the affected area, such as redness, swelling, pain, or discharge. If you develop a fever or other symptoms, seek medical care immediately. #medicalattention #earlytreatment #skininfection Jason McClellan's Story Jason McClellan's experience with necrotizing fasciitis is a cautionary tale about the dangers of skin infections. After being misdiagnosed several times, McClellan finally received the correct diagnosis and underwent a series of surgeries to remove the infected tissue. He spent months recovering, learning to walk again, and dealing with the physical and emotional scars of his ordeal. But McClellan feels fortunate to be alive and hopes that his story will encourage others to take skin infections seriously. #cautionarytale #survivor #flesheatingillness Summary: Necrotizing fasciitis is a rare but deadly bacterial infection that can quickly destroy muscles, skin, and tissue. To stay safe, practice good hygiene, avoid contact with contaminated water or soil, and seek medical attention for any signs of a skin infection. Jason McClellan's story serves as a reminder of the importance of taking skin infections seriously. #skincare #prevention #medicalattention #cautionarytale #survivor #flesheatingillness #HEALTH Read the full article

[drmilindcom]

Rare Flesh-Eating Bacteria: What You Need to Know 

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[lokeshbhadra-blog]

Necrotizing Fasciitis Treatment Market describes its growth, size, share, Forecast and trends to 2025

Necrotizing Fasciitis Treatment Market Production and Demand Analysis 2019 to 2025

Necrotizing Fasciitis Treatment Market 2019 Manufacturing Analysis and Development Forecast 2025

Necrotizing Fasciitis Treatment Market 2019: Recent Study Including Growth Factors, Regional Drivers, Forecast 2025

Necrotizing Fasciitis Treatment Market to Insight By 2025: Top Key Vendors

Necrotizing fasciitis NF, commonly known as flesh-eating disease, is an infection that results in the death of the bodys soft tissue. It is a severe disease of sudden onset that spreads rapidly. Symptoms include red or purple skin in the affected area, severe pain, fever, and vomiting. The most commonly affected areas are the limbs and perineum.

Necrotizing fasciitis affects 0.4 to 1.0 person per 100,000 per year. Both sexes are affected equally. It becomes more common among older people and is very rare in children. Surgical debridement cutting away affected tissue is the mainstay of treatment for necrotizing fasciitis. Early medical treatment is often presumptive; thus, antibiotics should be started as soon as this condition is suspected. Cultures are taken to determine appropriate antibiotic coverage, and antibiotics may be changed when culture results are obtained. Besides blood pressure control and hydration, support should be initiated for those with unstable vital signs and low urine output.

Download free PDF Sample copy of Necrotizing Fasciitis Treatment Market at https://www.qandqmarketresearch.com/report-sample/118597

Key Stakeholders of Necrotizing Fasciitis Treatment Market:

Necrotizing Fasciitis Treatment (Drugs/Medicine) Manufacturers

Necrotizing Fasciitis Treatment (Drugs/Medicine/Medical Equipment) Distributors/Traders/Wholesalers

Necrotizing Fasciitis Treatment Sub Component Manufacturers

Industry Association

Downstream Vendors

The Necrotizing Fasciitis Treatment Market continues to witness a major demand-supply gap, with one of the major impediments being absence of certified Necrotizing Fasciitis Treatment Producers are continuing to innovate and invest at the mill level, meanwhile partnering with relevant industries for addressing the rising requirement.

A quick look at the industry trends and opportunities:

The Researches find out why sales of Necrotizing Fasciitis Treatment is projected to surge in the coming years. The study covers the trends that will strongly favor the industry during the forecast period, 2019 to 2025. Besides this, the study uncovers important facts associated with lucrative growth and opportunities that lie ahead for the Necrotizing Fasciitis Treatment industry.

In this study, the years considered to estimate the market size of Necrotizing Fasciitis is as follow:

History Year: 2018

Base Year: 2018

Estimated Year: 2019

Forecast Year 2019 to 2025

Download free PDF Sample copy of Necrotizing Fasciitis Treatment Market Research Report at https://www.qandqmarketresearch.com/report-sample/118597

Key Points from TOC:

2 Global Growth Trends

2.1 Necrotizing Fasciitis Market Size

2.2 Necrotizing Fasciitis Growth Trends by Regions

2.2.1 Necrotizing Fasciitis Market Size by Regions 2014-2025

2.2.2 Necrotizing Fasciitis Market Share by Regions 2014-2019

2.3 Industry Trends

2.3.1 Market Top Trends

2.3.2 Market Drivers

2.3.3 Market Opportunities

 3 Market Share by Key Players

3.1 Necrotizing Fasciitis Market Size by Manufacturers

3.1.1 Global Necrotizing Fasciitis Revenue by Manufacturers 2014-2018

3.1.2 Global Necrotizing Fasciitis Revenue Market Share by Manufacturers 2014-2018

3.1.3 Global Necrotizing Fasciitis Market Concentration Ratio CR5 and HHI

3.2 Necrotizing Fasciitis Key Players Head office and Area Served

3.3 Key Players Necrotizing Fasciitis Product/Solution/Service

3.4 Date of Enter into Necrotizing Fasciitis Market

3.5 Mergers & Acquisitions, Expansion Plans

 4 Breakdown Data by Type and Application

4.1 Global Necrotizing Fasciitis Market Size by Type 2014-2019

4.2 Global Necrotizing Fasciitis Market Size by Application 2014-2019

Continue......

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[megaslicedmango]

Flesh-Eating Bacteria and Floodwaters

BACKGROUND Hurricane Harvey inundated Houston with 9 trillion gallons of water. Equivalent with a 1,000-year flood, this amount of water could be used to fill 14 million Olympic-sized swimming pools. With floodwaters carrying contaminants from superfund sites, dry cleaners, and sewer treatment facilities into residential areas, the risks of contracting a bacterial infection are heightened. With survival and preservation on the minds of the victims, many of them willingly expose themselves to contaminated waters without taking precautions. Four weeks after the storm, a 77-year-old woman contracted a flesh-eating disease after she fell helping clear out her son’s home. The woman did not survive and her cause of death was necrotizing fasciitis. Nearly two months later, a 31-year-old man succumbed to a wound on his arm while helping repair building infrastructure in Galveston county, about 50 miles away from Houston. Again, the cause of death of necrotizing fasciitis. 

FLESH-EATING DISEASE Nectrotizing fasciitis is a bacterial skin infection that kills soft tissue. The disease is caused by multiple bacteria types including Group A Streptococcus, Klebsiella, Clostridium, Escherichia coli, Staphylococcus aureus, and Aeromona hydrophila. According to the CDC, Group A streptococcus is the most common cause of necrotizing fasciitis and is transmitted via inhalation or mucous membrane transmission of infectious droplets. When the bacteria infects connective tissue, or fascia, and produces toxins, it causes necrotizing fasciitis. Even though the CDC considers this a rare phenomenon, those with compromised immune symptoms are more susceptible. 

YOU SHOULD BE WORRIED ABOUT NECROTIZING FASCIITIS WHEN... Although the 77-year-old woman was in good health and making positive progress after being hospitalized, her death was abrupt and unexpected. The doctors had thought they had treated the infection and were optimistic about her prognosis.  After two weeks in the ICU, she had suddenly passed. According to the CDC and Dr. David Persse (public health authority for Houston), the most worrisome indicator would be an increase of more than 0.5 inches of redness/swelling from the wound site in a two hour timespan. 

THIS IS IMPORTANT BECAUSE... Since 2010, the incidence rate is 600 to 1200 per year. Given a US population of 324 million, the odds of each of these cases happening was .0004%. Compare this to being struck by lightning, which is 0.0001%. With the idea that necrotizing fasciitis could be prevented with proper wound care, the disease should be at least less likely than being struck by lightning!

SOURCES http://www.cnn.com/2017/09/28/health/houston-flood-flesh-eating-bacteria/index.html

time.com/4996593/flesh-eating-bacteria-hurricane-harvey/

http://www.npr.org/2017/08/28/546831703/hurricane-harvey-dumps-trillions-of-gallons-of-water-on-texas

https://www.cdc.gov/features/necrotizingfasciitis/index.html

https://www.cdc.gov/groupastrep/index.html

https://www.washingtonpost.com/news/energy-environment/wp/2017/08/29/houstons-flood-threatens-to-turn-polluted-superfund-sites-into-a-toxic-gumbo/?utm_term=.220f724aeb7b

http://www.cnn.com/2017/09/01/health/houston-flood-water-contamination/index.html

[aeysheajones]

Some paintings of bacteria and viruses I created this week for one of my lovely friends birthday, had such fun painting these! #boutiqueofthekitschandstrange #painting #paintersgunnapaint #virus #bacteria #underthemicroscope #biology #science #necrotizingfasciitis #meningicoccal #hpv #tonsillitis #herpes #ebola #watercolourpaintings #viruspaintings