#pca 2015

[noirandchocolate]

RICE Alzheimer's Research Institute

Terry died on 12 March 2015, having given his PCA a run for its money.  Open about his diagnosis, he has helped to unlock the secrecy and stigma that often surrounds dementia.  His legion of fans is undoubtedly grateful that despite the inevitable progression of the PCA he was able to fight his ‘embuggerance’ and continue to produce a number of both well-received and well-reviewed books.  Terry was also a great example to me in emphasizing how important it is that, in caring for people with any type of dementia, we always look for what people with a condition like PCA can still do, rather than what they can’t: by maximizing what is possible, a person can still live well with dementia for a significant time.

–Professor Roy Jones, Director of RICE (taken from “Terry Pratchett: His World”)

I wanted to post something for the Glorious 25th about the Research Institute for the Care of Older People (RICE) in Bath, where Sir Terry Pratchett received treatment for Post-Cortical Atrophy, the type of Alzheimer’s disease that eventually took his life. From the organization’s website:

RICE established one of the first memory clinic services in the UK in 1987 – a service which has since been widely replicated and is now considered standard and best practice by the NHS. In fact, RICE now runs the NHS Memory Clinic in Bath and North East Somerset on behalf of the local clinical commissioning group and local authority through a sub-contract with HCRG Care Group. To date, we’ve assessed, diagnosed, treated and advised 12,000 people with memory problems and their families in our memory clinic. 

Most of RICE’s clinical services and research activities take place in our own purpose built, specialist centre located on the Royal United Hospital site. The building of the RICE Centre was possible as a result of generous donations from major donors, trusts and foundations, and members of the public. RICE moved into the ground and first floor of the centre in 2008. Following the success of the DementiaPlus Appeal and further generous donations from major donors, trusts and foundations and members of the public, RICE converted the attic floor in 2019 to create more office space. This has given us access to much needed additional rooms and offices which will enable us to grow and run more services and activities. We’ve worked hard to ensure that the areas of the centre visited by our patients meets their needs and we regularly receive feedback on how much our patients enjoy their visit to our centre.

RICE not only provides clinical services to patients, but also conducts research into aging and dementia, including performing clinical trials for new drug treatments for memory-related diseases and developing other “techniques for diagnosing, managing, treating and understanding dementia and memory changes in older adults.”

Lady Lyn Pratchett is the patron of the organization, and the website includes a page about how people can donate funds or volunteer at the clinic and participate in fundraising events.

SO, if you’d like to help fund Alzheimer’s research on this Glorious 25th of May–or at any time–in honor of the Man in the Hat, take a look!

[historyofglee]

On this day in 2015:

Glee won Favourite Comedic TV Actor (Chris Colfer) at the 41st annual People’s Choice Awards.

The awards were held at the Nokia Theatre in Los Angeles, California, however this category was not televised and Chris was not in attendance.

Chris did share a celebratory post on Instagram, stating: “Just found out about the #PCA award! Three years in a row?!?! Thank you all so much!!! The category wasn’t televised so let me tell you now I am forever grateful, humbled, and quite spoiled! As promised, here’s a video of Coop, Brian and I dancing to Taylor Swift.”

View this post on Instagram

A post shared by Chris Colfer (@chriscolfer)

[roe-and-memory]

in due honor of darlington throwback weekend and i (memory) attending my first ever nascar race in person, how about piston cup throwback weekend with a couple of the drivers?

throwback weekend in darlington originally started in 2015, and because of its popularity, its made rounds every year since then as a staple in the season. i think for the piston cup, its start should be pushed to around 2008.

for lightnings first ever throwback weekend, happening at the age of 19 (near 20) in 2008, the rusteze crew would go ALL OUT making his car reminiscent of docs. he gets the blue, the accurate colours, and they get “fabulous lightning mcqueen” down the side. they get permission from PCA to move lightnings numbers to the back quarter panel just above the rear wheel well of his car, and they happily place their sponsor on the trunk of the car and on the hood where doc would usually have “twin h power”

cals throwback would probably be something similar, rather, he would do a throwback scheme to his grandfather. dinoco has had roots in his family since the PCA was founded in 1948 and his grandfather raced for the company, the owners of it being longtime family friends (as tex and strip are still to this day). however, in the 50s, dinoco had a green and red scheme that consisted of a stegosaurus. his scheme would end up being simple (akin to lightnings with doc) but rather he’d have a changed number font, a mainly green car with racing stripes up and down the sides in red, and the upper portion of the car would cut off the green and be that cream/white colour. the original dinoco logo would be placed on either of the front quarter panels, and the hood would have his numbers on either side (a red stripe down the center of the car running from the front to the back), completely reminiscent of his grandfathers car (and a wee bit of nostalgia for strip)

bobby’s throwback, since he doesnt necessarily have roots in racing, would be to octane gains original sponsor (as it, as well as dinoco, had a place in the PC in the 50s). octaine gains original colour scheme was orange, black, and white. due to the nature and simplicity of cars from the 50s, it would end up as that orangey-yellow car, with black and white numbers, along with the typical ford trim down the side (the silver trim with the white triangle in the middle as it goes down the side of the car to meet the wheel well), as ford was the make of the original car they had sponsored way back when, and bobbys ride is the COT ford fusion. octane gains logo would end up right above the rear wheel, and like cals car, the upper portion of it (from the window to the top of the car) would be white.

[adeadhorse]

I haven’t gotten a chance to watch the Zoey 102 movie until recently. I walked in with really really low expectations. Some people are definitely trashing it because of the whole controversy with Britney (which is complex and more layer than people would like to believe) and not focusing on the actual film.

It was actually not bad at all. I quite enjoyed it and it was pretty fun compared to most reboots of our childhood shows that I’ve seen. I didn’t love it, but I didn’t hate it. A solid 6/10. The only issue is that I felt that it was a bit rushed (causing hurried explanations and a bit lack of chemistry between certain characters) A one season reboot show would have actually worked better in this case to build the story more carefully.

I know that the director recently said in an interview that they are think about a sequel movie. I wouldn’t be mad at it if they give it a better pace and give the other characters more screen time (especially scenes with Michael, Logan and Chase)

I’m not sure if you watched the movie yet or intend to but someone like yourself (who based on your writing really knows the depth of these characters and their world) I would love to hear your opinion of the movie if you ever do.

Hello, I am glad you enjoyed it! I agree with you that people solely bashing the show because of what happened with Britney and Alexa gets tiresome, because the original show had some merit despite those issues, and because you can just decide to not watch the movie instead of constantly talking about it (it's not like anyone is really on JL's side anyway).

I have no intention of watching it but @queenlova101 kindly gave me an extremely thorough rundown. To be blunt, I hated it. The downside of writing these characters for thousands of words is you do get to "know" them, so I think it's possible that I would have hated a reboot no matter how good it was because it was different to my version of them. Part of that is circumstance - anything is possible in a fanfic, compared to real life where you have budgets and availabilities. But I've seen other people say it didn't really feel like the original show, and to me they just made some baffling choices that shows they had no idea what the fans actually wanted or even liked about the original show.

Zoey should not be the main character to that extent (or at all really. Also why is she a producer), you should pander to the Quogan fans more, and most of all, you should have Chase and Michael (and Logan, but especially those two) interact as much as possible instead of not at all. I hate What Did Zoey Say with a passion, and Dan could not write for shit in 2015, but even he got that right. It feels like they told ChatGPT to write a script only going off the character names and every rom-com that got released c. 2008-2012.

I agree with you about the one-season reboot. Before I started actually writing fanfic I semi-planned out a season and a movie because I was more interested in screenwriting at the time. So again, I feel like I have potentially thought more about this show than anyone actually involved in the movie, so being disappointed was somewhat inevitable. I am also, at my core, a hater.

I personally hope they don't do a sequel movie or anything else. Neither attempt at an "adult" continuation has worked, it's just fallen into the trap most other reboots have of not having them change since high school and undermining a lot of what people liked about the show (I don't love PCA but that's! The main! Draw! You just shot yourself in the foot!). Frankly I would just like them to put the S3 cast (minus JL) in a new show with similar vibes and call it a day. That I think would actually be fun, and would make more sense than whatever they are doing now.

[unicausnews]

Parvathy Sundaram (left) and Venugopal Bhaskaran Nayar (Right). File | Photo Credit: Special Arrangement Indel Money, a gold mortgage NBFC, has introduced the appointment of Parvathy Sundaram, Former Executive Director, Reserve Bank of India (RBI) , and Venugopal Bhaskaran Nayar, former Managing Director of Life Insurance Corporation of India (LIC), as Independent Directors on its Board.  Umesh Mohanan, ED & CEO, Indel Money, mentioned, “Their wealth of expertise in regulatory and monetary companies will likely be instrumental as we chart our subsequent part of progress and proceed constructing management in core retail, secured asset classes.” Ms. Sundaram was straight concerned within the Asset Quality Review (2015–17), the shift to Risk-Based Supervision, and the event of a framework for small international banks on the RBI. She additionally contributed to the revised Prompt Corrective Action (PCA) pointers and took part in RBI working teams on MCLR and the Public Credit Registry. Mr. Nayar has over 38 years of expertise in monetary companies, together with 36 years with LIC. He retired as Managing Director in May 2019. Since retirement, he has served as an Independent Director at SBI Life Insurance and on the boards of establishments together with SBI (as an Independent Director until 2024), NCDEX, LIC Nepal, LIC Bangladesh, and LIC International. Published - July 11, 2025 09:56 pm IST Read More: https://news.unicaus.in/business/indel-money-inducts-ex-rbi-ed-lic-md-into-its-board/

[thecigarguys]

The Premium Cigar Association (PCA) 2025: A Smoky Sanctuary for the Cigar Industry

The Premium Cigar Association (PCA) 2025 Trade Show, held from April 11 to April 14 at the Ernest N. Morial Convention Center in New Orleans, Louisiana, was a triumphant return to the Crescent City for the first time since 2015. As the world’s premier B2B event for the premium cigar and pipe tobacco industry, PCA25 solidified its reputation as a cornerstone of the specialty tobacco world,…

[evoldir]

Fwd: Course: UPretoria_SouthAfrica.ConservationGenetics

Begin forwarded message: > From: evoldir@evol.biology.mcmaster.ca > Subject: Course: UPretoria_SouthAfrica.ConservationGenetics > Date: 1 October 2024 at 07:30:19 BST > To: rdmpage@gmail.com > > > Conservation Genetics and Wildlife Management Course and Workshop: > > Theme: Applications of Genetics in Wildlife Management, Molecular Ecology, > and Conservation Genetics. > > When: December 9-15, 2024 at the University of Pretoria, South Africa. > UP is one of Africa's top universities and the largest university in > South Africa. > > Course Objective: To train participants to understand and use population > genetics principles and DNA-marker data to improve biodiversity > conservation. The course will teach research approaches, monitoring, > data analyses, and interpretation (RADseq, amplicon-seq, targeted > capture, WGseq). The course will help bridge the gap between research > and management to improve conservation (e.g., Allendorf et al. 2022, > Chapter 24). This course is urgently needed and timely given the > extinction crisis and the recent Kunming-Montreal Global Biodiversity > Framework in which 196 parties committed to reporting the status of > genetic diversity for all species wild and domestic (Mastretta-Yates > et al. 2024; Hoben et al. 2024).  For details on ConGen-Africa: see > https://ift.tt/XkYw6iP > > Who should apply: Advanced Undergrads, M.S. & Ph.D. students, post-docs, > faculty, agency researchers, and population biologists. To maximize > benefits from days 3-5, attendees should have taken a course in population > genetics and population ecology - or understand most of Chapters 4-10 in > the book Allendorf et al. 2024). Participation on days 3-5 is limited > to ~30 people to allow efficient instruction with hands-on computer > exercises. > > Dates and Content: Monday - Friday, Dec. 9-13, 2024.  9 am to 4 > PM daily. The first two days include basic concepts (mechanisms of > evolutionary change) and applications of genetics for conservation. Days > 3-5 include hands-on data analysis and interpretation using > microsatellites, SNPs, and next-generation sequence datasets) using > popular programs like Structure, NeEstimator, GeneClass/RUBIAS, and > packages in Rstudio on days 4-5. > > You will learn (or review) the following including real-life examples > (as in the book Allendorf et al. 2022): > >  1.  mechanisms of evolutionary change: genetic drift, gene flow, >      selection, & mutation (days 1-2) >  2.  importance of testing for Hardy-Weinberg proportions and linkage >      disequilibrium (some basic knowledge of HW- and LD-testing is >      recommended mainly for days 3-5) >  3.  basic use of R (writing simple command line arguments to make >      graphs, and conduct statistical tests, including HW tests and PCAs >      for population structure assessment. We'll teach use of R and >      command line programs during an online Zoom lecture one week >      before the course. R is the most widely used software and language >      in statistics and biology and increasingly for population genetics >      (Pardis 2020; Jombart & Ahmed 2011; Kamvar et al. 2015, 2016; >      Kardos & Luikart 2021; Kardos et al. 2022; Hemstrom & Jones 2023; >      Zhang et al. 2023; Yang et al. 2023; Jenkins 2024; Bailey 2024). >  4.  Participants should have an advanced understanding of spoken and >      written English > > Field trips to Kruger National Park & Mabula Hornbill Sanctuary are > possible, including wildlife safari drives (TBA). > > Main Instructors: Gordon Luikart, Will Hemstrom, Other local and > international instructors to be announced > > > "Luikart, Gordon"

[ef-fetto-notte]

Google’s Word2vec Patent

Word2vec is a method of computing vector representations of words introduced by a team of researchers at Google led by Tomas Mikolov. Google hosts an open-source version of Word2vec released under an Apache 2.0 license. In 2014, Mikolov left Google for Facebook, and in May 2015, Google was granted a patent for the method, which does not abrogate the Apache license under which it has been released.

Foreign Languages

While words in all languages may be converted into vectors with Word2vec, and those vectors learned with Deeplearning4j, NLP preprocessing can be very language specific, and requires tools beyond our libraries. The Stanford Natural Language Processing Group has a number of Java-based tools for tokenization, part-of-speech tagging and named-entity recognition for languages such as Mandarin Chinese, Arabic, French, German and Spanish. For Japanese, NLP tools like Kuromoji are useful. Other foreign-language resources, including text corpora, are available here.

Sequence Vectors

Deeplearning4j has a class called SequenceVectors, which is one level of abstraction above word vectors, and which allows you to extract features from any sequence, including social media profiles, transactions, proteins, etc. If data can be described as sequence, it can be learned via skip-gram and hierarchic softmax with the AbstractVectors class. This is compatible with the DeepWalk algorithm, also implemented in Deeplearning4j.

Doc2vec & Other NLP Resources

DL4J Example of Text Classification With Word2vec & RNNs

DL4J Example of Text Classification With Paragraph Vectors

Doc2vec, or Paragraph Vectors, With Deeplearning4j

Thought Vectors, Natural Language Processing & the Future of AI

Quora: How Does Word2vec Work?

Quora: What Are Some Interesting Word2Vec Results?

Word2Vec: an introduction; Folgert Karsdorp

Mikolov’s Original Word2vec Code @Google

word2vec Explained: Deriving Mikolov et al.’s Negative-Sampling Word-Embedding Method; Yoav Goldberg and Omer Levy

Bag of Words & Term Frequency-Inverse Document Frequency (TF-IDF)

Other Deeplearning4j Tutorials

Introduction to Neural Networks

Restricted Boltzmann Machines

Eigenvectors, Covariance, PCA and Entropy

LSTMs and Recurrent Networks

Neural Networks and Regression

Convolutional Networks

[blindmanspuff]

Room101 Johnny Tobacconaut Robusto - Blind Cigar Review

Room101 Johnny Tobacconaut Robusto - Blind #Cigar Review #cigars #blindmanspuff #SmokeBlind

Cigar Info Just over a year after STG (Scandinavian Tobacco Group) acquired Room101 Cigars, Matt Booth decided to re-release the Room101 Johnny Tobacconaut in a new blend at the PCA trade show 2023. Johnny Tobacconaut originally came out in 2015 and production stopped when Matt Booth departed from Davidoff. In 2022, Johnny Tobacconaut made a comeback of sorts as a limited-production cigar for…

[naturecoaster]

Pasco Animal Services Awarded $7,500 for Vet Equipment

Banfield Foundation® grant will help medical team check animals’ vital signs Pasco Animal Services Awarded $7,500 for Vet Equipment Pasco County Animal Services (PCAS) is the proud recipient of a $7,500 grant from Banfield Foundation to pay for lifesaving medical equipment that will help our furry friends in their time of need. “Our medical team’s expertise, skill and compassion allows us to maintain a save rate of more than 90%,” said PCAS Director Mike Shumate.  “We’re grateful to Banfield Foundation for helping us fulfil our mission of providing quality care for the animals in our shelter – when they need it most.” Grant money will be used for the following: - Two portable monitors for observing animal heart rate/oxygen levels after surgery - A tonometer to determine eye pressure Since 2015, Banfield Foundation has been making preventive care possible for the pets that need it most. Through grants and partnerships, the foundation provides medical supplies and resources to nonprofit partners in need; supports pets, people and communities in crisis; and enables veterinary professionals to deliver compassionate and inclusive preventive veterinary care in underserved and diverse areas across the U.S. and around the world. PCAS’ medical team is made up of the veterinary services supervisor, two veterinarians and six veterinary technicians.  In 2022, the team helped care for approximately 6,700 dogs and cats in our shelter. Pasco County Animal Services is dedicated to promoting and protecting the health, safety and welfare of animals and people. For more information, including a full list of programs and services, please visit our website at: MyPasco.net/PAS. Read the full article

[helpagirlout-lander]

Full Eps / HQ Stills / ScreenCaps by EP: 1x01, 1x02, 1x03, 1x04, 1x05, 1x06, 1x07 Parts One & Two & Three, 1x08, 1x09, 1x10, 1x11, 1x12, 1x13, 1x14, 1x15, 1x16

 Dressing Outlander / Making of The Wedding / A Day in the Life of Cait / Boot Camp (w/Italian Subs), (w/ Spanish Subs) / Gag Reel / An Epic Adaptation / Authentic in Design / Table Read // Inside the Ep:  1x07 Wedding / 1x09 (w/Italian Subs) /  1x12 Lallybroch / 1x13 The Watch / 1x16 Ransom 

Extended/Bonus Scenes: 1x06 / 1x07 / Ceremony First Version / 1x08 / 1x09 / Also 1x09 / Also Also 1x09 / Still 1x09 / 1x09 (w/Italian Subs) / 1x10 /  1x12 (w/Italian Subs) / 1x14 

Original Chemistry Test / Two

Trailers: “First Look”, First Look w/ Alternate Ending, Disappearance Trailer,  Claire Trailer, Journey Trailer, Official Trailer, Opening Titles,  Jamie Trailer, Critical Acclaim, Season Preview, Black Jack Randall Trailer, Highlanders Trailer, The Story Continues, In Production Now,  Love Trailer,  Home Trailer, Jamie’s Story Continues,  Claire’s Story Continues, Black Jack’s Story Continues

Time Warner Cable Commercial Spot

Scots Gaelic Pronunciations:  Sassenach / Craigh Na Dun / Mo Nighean Donn / Je Suis Prest / Happy Birthday

Greetings from The Cast: Happy Holidays / Happy New Year / Valentine’s Day / Sam Surprises Fans

Promo Videos w/ Cast Interviews:  New Series, Book to Series w/ Diana, Scotland, Trailer Sneak Peek, A Look Ahead, The Married Life, Meet the Frasers / Casting Sam as Jamie 

Scottish BAFTAs 2013: Daily Record 

The Outlander Fan Gathering (January 2014): Sam, Cait, Ron, & Diana:  Highlights, More Highlights, Q&A

BAFTA LA 2014 (January): w/ Cait: Red Carpet, Anglophile, Black Tree TV, FanVid

Golden Globes 2014 (July): HFPA 

SDCC (July 2014): Sam, Cait, Tobias, Graham, Lotte, Ron, & Diana: Highlights (w/ MBR & Maril) / 92Y+ Full Panel, BookReview /  Outlander Panel Part One, Two*, Three* & Four, Sam / Fan Faves Panel Part One, Two, Three, Four or Full Vid (Sam) /  HFPA / IGN (Sam, Cait, & Tobias) /  EW (w/ French Subs) (Sam, Cait, Tobias, Lotte, & Graham) / TVLine / Yahoo (Sam, Cait, & Tobias)

SDCC Premiere: Seat24F / That’s Normal / Outlander Insider / “TV” / OutlanderTV / Hypable / VisitScotland / TVAddict / Q&A Part One & Two (Sam, Cait, Tobias, Graham, Lotte, Ron, & Diana)

PCA 2015 (January): Sam & Cait:  Red Carpet / Awards / Against the Clock / NoahPopTV (w/ Portuguese Subs) / Chemistry / Fan Support/  Thanks

UK Premiere (March 2015): Sam, Cait, & Ron: Q&A / Red Carpet News

PaleyFest 2015 (March): Seat 42F: Sam & Cait, Sam / Kill Marry Screw / Sam / HitFix / Whedonpolis

The Tartan Affair/ MidSeason Premiere (April 2015): Highlights / Justine Browning (Sam, Cait, & Tobias) / That’s Normal / Q&A (Sam, Cait, Tobias, Graham, Lotte, Gary, & Ron)/ Hypable / TVAfterDark (Cait, Lotte, Tobias, Graham, Gary, and Sam) / RTBookReviews (Lotte, Graham, Gary, Tobias, Cait, & Sam)

Sam: w/ Kristin Dos Santos One & Two / GoldDerby (Trigger Warnings) / Wall St Journal (w/ Tobias) / ColliderExtras / That’s Normal / JustineBrowning / Celebrity Watch List / Drinking With The Stars, Two / Vanity Fair / DP30 / LATimes / FaveMoments / PopSugar / MTV / Be / PeopleNow 

Sam & Cait: AP (Love, Weather, and Stunts) / TV Guide: Cubicle Confessions One & Two (w/ Tobias), Photo Session, Best Fan Encounters, Love Story / Access Hollywood / Fox News Spot (w/ Tobias) / Time Warner Channel / SideWalks, Two / PopSugar, SugarRush / Lucy Tan (w/ Tobias) / BayArea /  E! Photoshoot / Yahoo (w/ Ron) / MorningBlend / Ones to Watch / Fox4 MorningBlend / FresnoBee / DishStudio / CBS This Morning (Sam, Cait, & Diana)) / AP “Downtime on Set” (Sam, Cait, Diana, & Ron) / EP Daily (Cait, Sam, Diana, & Ron)

Games: This or That / Read Your Tweets / Answer Your Questions & More Questions / Fave Moments / Would You Rather / Who Knows Better (w/ French Subs) / CoStar Challenge / Scottish Culture Quiz / Pop Culture Personality test / Season Finale in Three Words / Ten Seconds / Porn Parody Titles (wItalian Subs)

[evoldir]

Fwd: Course: UPretoria_SouthAfrica.ConservationGenetics

Begin forwarded message: > From: evoldir@evol.biology.mcmaster.ca > Subject: Course: UPretoria_SouthAfrica.ConservationGenetics > Date: 1 October 2024 at 07:30:19 BST > To: rdmpage@gmail.com > > > Conservation Genetics and Wildlife Management Course and Workshop: > > Theme: Applications of Genetics in Wildlife Management, Molecular Ecology, > and Conservation Genetics. > > When: December 9-15, 2024 at the University of Pretoria, South Africa. > UP is one of Africa's top universities and the largest university in > South Africa. > > Course Objective: To train participants to understand and use population > genetics principles and DNA-marker data to improve biodiversity > conservation. The course will teach research approaches, monitoring, > data analyses, and interpretation (RADseq, amplicon-seq, targeted > capture, WGseq). The course will help bridge the gap between research > and management to improve conservation (e.g., Allendorf et al. 2022, > Chapter 24). This course is urgently needed and timely given the > extinction crisis and the recent Kunming-Montreal Global Biodiversity > Framework in which 196 parties committed to reporting the status of > genetic diversity for all species wild and domestic (Mastretta-Yates > et al. 2024; Hoben et al. 2024).  For details on ConGen-Africa: see > https://ift.tt/XkYw6iP > > Who should apply: Advanced Undergrads, M.S. & Ph.D. students, post-docs, > faculty, agency researchers, and population biologists. To maximize > benefits from days 3-5, attendees should have taken a course in population > genetics and population ecology - or understand most of Chapters 4-10 in > the book Allendorf et al. 2024). Participation on days 3-5 is limited > to ~30 people to allow efficient instruction with hands-on computer > exercises. > > Dates and Content: Monday - Friday, Dec. 9-13, 2024.  9 am to 4 > PM daily. The first two days include basic concepts (mechanisms of > evolutionary change) and applications of genetics for conservation. Days > 3-5 include hands-on data analysis and interpretation using > microsatellites, SNPs, and next-generation sequence datasets) using > popular programs like Structure, NeEstimator, GeneClass/RUBIAS, and > packages in Rstudio on days 4-5. > > You will learn (or review) the following including real-life examples > (as in the book Allendorf et al. 2022): > >  1.  mechanisms of evolutionary change: genetic drift, gene flow, >      selection, & mutation (days 1-2) >  2.  importance of testing for Hardy-Weinberg proportions and linkage >      disequilibrium (some basic knowledge of HW- and LD-testing is >      recommended mainly for days 3-5) >  3.  basic use of R (writing simple command line arguments to make >      graphs, and conduct statistical tests, including HW tests and PCAs >      for population structure assessment. We'll teach use of R and >      command line programs during an online Zoom lecture one week >      before the course. R is the most widely used software and language >      in statistics and biology and increasingly for population genetics >      (Pardis 2020; Jombart & Ahmed 2011; Kamvar et al. 2015, 2016; >      Kardos & Luikart 2021; Kardos et al. 2022; Hemstrom & Jones 2023; >      Zhang et al. 2023; Yang et al. 2023; Jenkins 2024; Bailey 2024). >  4.  Participants should have an advanced understanding of spoken and >      written English > > Field trips to Kruger National Park & Mabula Hornbill Sanctuary are > possible, including wildlife safari drives (TBA). > > Main Instructors: Gordon Luikart, Will Hemstrom, Other local and > international instructors to be announced > > > "Luikart, Gordon"

[boyneriver-fraser]

Winner — Favourite Cable Sci-Fi/Fantasy TV Show: Outlander

Sam & Cait // PCA’s 2015

[camcabellailla]

[5htimeline]

January 7th

2015:

• People’s Choice Awards

[noirandchocolate]

RICE Alzheimer's Research Institute

Terry died on 12 March 2015, having given his PCA a run for its money.  Open about his diagnosis, he has helped to unlock the secrecy and stigma that often surrounds dementia.  His legion of fans is undoubtedly grateful that despite the inevitable progression of the PCA he was able to fight his ‘embuggerance’ and continue to produce a number of both well-received and well-reviewed books.  Terry was also a great example to me in emphasizing how important it is that, in caring for people with any type of dementia, we always look for what people with a condition like PCA can still do, rather than what they can’t: by maximizing what is possible, a person can still live well with dementia for a significant time.

--Professor Roy Jones, Director of RICE (taken from “Terry Pratchett: His World”)

I wanted to post something for the Glorious 25th about the Research Institute for the Care of Older People (RICE) in Bath, where Sir Terry Pratchett received treatment for Post-Cortical Atrophy, the type of Alzheimer's disease that eventually took his life. From the organization's website:

RICE established one of the first memory clinic services in the UK in 1987 – a service which has since been widely replicated and is now considered standard and best practice by the NHS. In fact, RICE now runs the NHS Memory Clinic in Bath and North East Somerset on behalf of the local clinical commissioning group and local authority through a sub-contract with HCRG Care Group. To date, we’ve assessed, diagnosed, treated and advised 12,000 people with memory problems and their families in our memory clinic. 

Most of RICE’s clinical services and research activities take place in our own purpose built, specialist centre located on the Royal United Hospital site. The building of the RICE Centre was possible as a result of generous donations from major donors, trusts and foundations, and members of the public. RICE moved into the ground and first floor of the centre in 2008. Following the success of the DementiaPlus Appeal and further generous donations from major donors, trusts and foundations and members of the public, RICE converted the attic floor in 2019 to create more office space. This has given us access to much needed additional rooms and offices which will enable us to grow and run more services and activities. We’ve worked hard to ensure that the areas of the centre visited by our patients meets their needs and we regularly receive feedback on how much our patients enjoy their visit to our centre.

RICE not only provides clinical services to patients, but also conducts research into aging and dementia, including performing clinical trials for new drug treatments for memory-related diseases and developing other "techniques for diagnosing, managing, treating and understanding dementia and memory changes in older adults."

Lady Lyn Pratchett is the patron of the organization, and the website includes a page about how people can donate funds or volunteer at the clinic and participate in fundraising events.

SO, if you'd like to help fund Alzheimer's research on this Glorious 25th of May--or at any time--in honor of the Man in the Hat, take a look!