Tumgik
hg-pharm · 1 year
Text
Tumblr media
0 notes
hg-pharm · 2 years
Text
LGD 4033 stack: Best stack suggestions
One of the most popular SARMs on the market today, LGD 4033 (also known as Ligandrol) is a non-steroidal oral selective androgen receptor modulator with strong muscle building properties. In recent years, more and more bodybuilding enthusiasts have begun to use LGD 4033 in the process of bodybuilding. With the increase of users, some users are not satisfied with using LGD 4033 alone and begin to use LGD 4033 stack to obtain larger the effect. This article will introduce some LGD 4033 stack recommendations at different times for your reference.
Tumblr media
LGD 4033 Bulking Cycle
The LGD 4033 itself is great for bulking, and many users find that this one SARM alone can meet their bulking needs. Only those looking for more extreme results would want to stack the LGD 4033 with something else in the Bulking Cycle. Our suggestion for this is:
If you are not keen on very extreme bulking needs, then you can only choose to use LGD 4033 to achieve your goals, while in the bulking cycle, you need to ensure a protein rich diet and a higher calorie intake.
If you are keen on very extreme bulking needs, the common bulking stacks are LGD 4033 and RAD 140, the recommended dosage is LGD 4033 10mg per day, RAD 140 10mg per day, while maintaining protein and calorie intake, which will keep you in Gain 20 pounds and above in an 8-week cycle.
LGD 4033 Cutting Cycle
It is well known that LGD 4033 has a strong ability to preserve lean muscle mass. In the cutting cycle, bodybuilders will inevitably lead to the loss of lean muscle mass. Therefore, LGD 4033 can be used in the cutting cycle to stack with other SARMs with strong fat-reducing ability to ensure that the body will not be trapped in muscle while losing fat. catabolic state of energy. Our suggestion for this is:
The dose of LGD 4033 was reduced to 5 mg per day, and it was stacked with GW 501516 (cardarine) and MK 2866 (Ostarine). This ensures that you avoid the loss of lean muscle mass during the fat loss process.
LGD 4033 Recomping Cycle
LGD 4033 is one of the most suitable SARMs for Recomping Cycle. Many users report that they have observed an increase in lean body mass and a loss in fat during use. In this process, you can stack it with GW501516 (Cardarine) for maximum effect The above contents are LGD 4033 Stack recommendations for users at different times. Since the emergence of SARM, there are many different stacking methods, and users can stack according to their actual situation.
0 notes
hg-pharm · 2 years
Text
How much weight will I gain on LGD 4033?
How much weight will I gain on LGD 4033? Seeing this title, I believe many people will want to know in detail, this article will give you the answer.
When people use a drug or supplement, they often focus on what kind of benefits they will get after using the product. Different drugs or supplements have different benefits, and some drugs are used to prevent certain diseases. , Some drugs are used to treat certain diseases, some drugs such as SARM LGD 4033 are used to Build Muscle.
Tumblr media
Benefits of LGD 4033
LGD 4033, also known as Ligandrol, is a non-steroidal oral selective androgen receptor modulator (SARM), which was originally developed for the treatment of muscle wasting and osteoporosis caused by certain diseases, etc., due to LGD 4033 Powerful efficacy in the bodybuilding process, it is popular with bodybuilders and known as one of the most powerful SARMs. It is well known that LGD 4033 can selectively bind to androgen receptors in muscle tissue, thereby promoting protein synthesis, and protein is an important part of muscle, so one of the benefits of LGD 4033 is to accelerate muscle growth. This is the most important benefit of LGD 4033, if you want to know more, you can click here to learn more.
How much weight will I gain on LGD 4033?
The recommended dose of LGD 4033 is 10mg per day for a 12-week cycle, during which you will gain 12 to 18 pounds of pure muscle and gain 50-60 pounds in all major lifts.
Nearly all of them gained 12 to 18 pounds of lean muscle and got stronger, according to customer feedback they used for 12 weeks.
In my case, when I went through a 12 week LGD 4033 cycle, I gained about 15 lbs of muscle and my strength improved significantly.
During the use of the LGD 4033, my strength has barely diminished, even during prolonged workouts, which allows me to perform repetitively my heavy training.
I also felt a huge increase in stamina during use, my muscles felt and looked much plumper than ever, and the best part was that my gains were very dry. Almost no water storage takes place.
To sum up, regular use of LGD 4033 for a 12-week cycle can allow you to gain 12 esters and 18 pounds of pure muscle and have a significant increase in strength and endurance.
0 notes
hg-pharm · 2 years
Text
Does LGD 4033 Build Muscle?
Does LGD 4033 Build Muscle? This is a question that many beginners will be concerned about, this article will take you to understand in detail.
Tumblr media
  What is LGD4033?
LGD 4033, also known as Ligandrol, is a non-steroidal oral selective androgen receptor modulator (SARM) developed by Ligand Pharmaceuticals, an American biotechnology company, for the treatment of muscle wasting and osteoporosis. As researchers continue to study it, LGD 4033 has gradually been widely used in the field of bodybuilding.
How LGD 4033 Work?
As we all know, the human body is in the process of protein synthesis every day. Protein is an important part of muscle. For anyone who wants to increase muscle mass, protein synthesis is an essential part of the body to build new muscle tissue, LGD 4033 binds to androgen receptors in muscles, thereby triggering protein synthesis in muscle tissue, and increased protein synthesis in muscle tissue, which means faster muscle growth, allowing users to achieve rapid muscle gain. At the same time, compared with anabolic steroids, due to its selectivity, LGD 4033 has almost no affinity for androgen receptors in organs such as prostate and liver, and will not cause side effects to users like anabolic steroids. Not only does LGD 4033 promote muscle growth, it also helps prevent muscle atrophy. Beginners looking to gain weight and build quality muscle should definitely consider LGD 4033.
By understanding the working principle of LGD 4033, you can know the answer to the question Does LGD 4033 Build Muscle?
SARM LGD 4033 can Build Muscle.
in conclusion
LGD 4033 is a powerful SARM that can help you Build Muscle. With its highly anabolic properties, LGD 4033 is also very effective in promoting muscle growth in people who are naturally thin or have difficulty gaining weight.
For women, the recommended dose of LGD 4033 for building muscle is 5 mg once daily for 8-12 weeks as a cycle.
For men, the recommended dose of LGD 4033 for building muscle is 10 mg once daily for 8-12 weeks as a cycle.
After the cycle is completed, users are advised to temporarily stop using LGD 4033 for a few weeks to allow the body to gradually return to normal.
0 notes
hg-pharm · 2 years
Text
LGD 4033 side effects:What you need to know before using it?
Pursuing advantages and avoiding disadvantages is the fundamental principle for the survival and development of organisms. When people use a drug, they often pay attention to its benefits, but its side effects cannot be ignored. LGD 4033 is an oral non-steroidal selective androgen receptor modulator, a compound that targets specific androgen receptors in the body, the main function is to increase muscle growth and bone density, and for Bodybuilders, it has a powerful Therefore, LGD 4033 is becoming more and more popular with Bodybuilders. Although it is powerful, the LGD 4033 side Effects cannot be ignored.
Tumblr media
LGD 4033 side effects
Two known minor side effects associated with LGD 4033 are headache and dry mouth. However, more troublesome side effects can also occur.
1. Cholesterol
LGD 4033 may lead to lower HDL cholesterol. The researchers observed users who used a dose of 1 mg/day and found that the HDL cholesterol in the user's body was reduced by nearly 40% in just 3 weeks, and the reduction in HDL cholesterol may be Increases the risk of arteriosclerosis and harms heart health. This change may be attributed to the need for oral administration of LGD 4033 to pass through the liver by stimulating the enzyme hepatic lipase, thereby causing this change in HDL cholesterol. In this study, researchers found that LDL cholesterol levels remained stable, while serum triglycerides were reduced by 15%, possibly reducing some cardiovascular stress.
2. Testosterone Suppression
Although LGD 4033 is a non-steroidal drug, it still inhibits natural testosterone levels by selectively binding to androgen receptors. In trials where 1 mg/day of LGD 4033 was given, participants' total testosterone levels dropped by 50%. Free testosterone also experienced a similar 40% drop.
The user's endogenous testosterone does not return to normal levels until a period of time after the drug is discontinued.
Therefore, users need to perform PCT with appropriate drugs after using LGD 4033 cycles.
3. Hepatotoxicity
In a phase 1 clinical trial of 76 adult men, through the observation of different doses, the change in the user's net weight gain was positively correlated with the dose, and obvious side effects occurred in the afternoon of the 21-day test, which can be seen the hepatotoxicity of LGD 4033 was minimal.
Through the above introduction, we can understand the side effects of SARM LGD 4033, but due to the difference in human body constitution, different people have different tolerance to LGD 4033. Users can use it according to their own conditions. Once serious side effects are found, please stop the drug immediately and consult a doctor.
0 notes
hg-pharm · 2 years
Text
Mesterolone/Proviron is a proper AAS for stacking
For experienced Bodybuilders, it is rare to use only one AAS in their cycle, and Mesterolone/Proviron is a proper AAS for stacking.
Mesterolone/Proviron act as AI to help other AAS avoid aromatization
Studies have shown that long-term use of high doses of Mesterolone has no serious inhibitory effect on endogenous testosterone. A daily dose of 150mg or less of Mesterolone has no significant inhibiting testosterone results. The normal dose did not inhibit HPTA. As a result, some Bodybuilders try to use Mesterolone during PCTS to maintain revenue. Later studies have shown that Mesterolone inhibits LH(luteinizing hormone) in some cases. Because Mesterolone has a high affinity with aromatase, the use of Mesterolone by bodybuilder during the AAS cycle can act as an anti-estrogen agent. Although Mesterolone is not as active as Aromasin, Arimidex or Letrozole as an aromatase inhibitor, it is still effective and can be used as such. Its strength as an aromatase inhibitor is comparable to that of Arimidex, but slightly lower. Therefore, bodybuilder can use it as an alternative to aromatase inhibitors during the AAS cycle.
Tumblr media
This property makes Mesterolone a proper AAS for stacking . Use Mesterolone stacked with AAS that are easily converted to estrogen by aromatase, such as power tonic, testosterone and its ester compounds, Norone, or Equipoise. bodybuilder can get a stiffer look with more veins. Less swelling of the muscles.
Mesterolone/Proviron prefer to combine with SHBG, helps other AAS act better
Mesterolone also has a very high affinity with sex hormone binding protein (SHBG), a hormone responsible for reducing the amount of free testosterone circulating in the body. When bodybuilder adds Mesterolone to the AAS stack, Mesterolone binds to SHBG preferentially. The release of more free testosterone also increases the activity of other AAS, allowing other AAS to function.
Mesterolone has weak synthetic metabolism and androgen, does not inhibit endogenous testosterone, and does not help muscle gain as much as some other AAS have high synthetic metabolism. As a result, when Mesterolone was used alone, the muscle gain was limited. However, Mesterolone does not aromatize and has a high affinity with aromatase, which prevents other AAS from being aromatized. Mesterolone is preferred to combine with SHBG, so that other AAS can play a better role. Mesterolone does not inhibit endogenous testosterone and does not give bodybuilder symptoms of low testosterone; Mesterolone, as an oral AAS, is easy to use without the pain and risk of infection associated with injection use. Mesterolone brings all kinds of benefits to show that it is a proper AAS for stacking.
Mesterolone acts as oral AAS and is stacked with other AAS or SARMs to avoid water retention for maximum muscle mass gain and a more aesthetically pleasing muscle appearance.
0 notes
hg-pharm · 2 years
Text
LGD 4033 half life:When to take LGD 4033?
LGD 4033 Half life refers to the time it takes for the concentration of LGD 4033 in the blood or the amount of LGD 4033 in the body to decrease to one-half. Knowing the half life of LGD 4033 can help bodybuilders determine the interval and time of use of LGD 4033. Learn about LGD 4033 half life and When to take LGD 4033 through this article.
Tumblr media
LGD 4033 Half life
LGD 4033, also known as Ligandrol, is the strongest orally bioavailable non-steroidal selective androgen receptor modulator (SARM) currently on the market. It was originally developed to treat conditions such as muscle wasting associated with acute and chronic diseases, age-related muscle loss, osteoporosis and cancer. For bodybuilders, LGD 4033 reduces body fat and increases muscle mass.
LGD 4033 has a strong bulking and cutting ability, so it is popular with athletes, powerlifters and bodybuilders. It has the same powerful ability as anabolic steroids, but without the side effects of anabolic steroids.
LGD 4033 is more and more popular with Bodybuilders. Before using LGD 4033, Bodybuilders must know its half-life to determine the usage interval.
To understand the half-life of LGD 4033, researchers have conducted numerous studies and determined that its half-life is 24 to 36 hours, so that a user taking once a day is sufficient to maintain LGD 4033 levels in the blood.
When to take LGD 4033?
Through the above introduction, it can be understood that LGD 4033 users only need to take it once a day to ensure the level of LGD 4033 in the blood. So when should LGD 4033 be taken each day for best results. Therefore, we conducted a large number of return visits, and through the introduction of most of our customers, we learned that the best time to take LGD 4033 is neither morning nor evening, but an hour before training.
why?
Because Bodybulders ingested LGD 4033 one hour after their LGD 4033 levels peaked, after one hour, they gradually began to decline. Through studies of its half-life, the amount of LGD 4033 in the blood will be reduced by 10% after six hours of ingestion of LGD 4033 by users. Therefore, the best practice is to take SARM LGD 4033 an hour before training, day or night (LGD 4033 does not interfere with sleep).
0 notes
hg-pharm · 2 years
Text
What is Mesterolone, the Mesterolone feature?
What is Mesterolone?
It is better known by its brand name Proviron than Mesterolone.
Mesterolone is an oral androgen and anabolic steroid (AAS) drug developed in the 1960s and introduced for medical use by Schering in 1967 under the brand name Proviron. It is a derivative of DHT, does not produce estrogen, has weak androgenic and anabolic effects, is used primarily to treat low testosterone levels, and has also been used to treat male infertility.
Product Name: Mesterolone
Other name: Proviron
CAS : 1424-00-6
MF: C20H32O2
MW: 304.47
EINCES: 215-836-3
Purity: 99%Min
Appearance: White powder
Package: 10g/bag or as customers'request.
Test Method: HPLC
Mesterolone feature
Weak androgenic and anabolic effects of Mesterolone
Mesterolone is an androgen receptor (AR) agonist and has relatively low androgen and anabolic potency due to the inactivation of 3α-hydroxy steroid dehydrogenase (3α-HSD) in skeletal muscle tissue, similar to DHT and Mestanolone. However, it still shows a greater ratio of anabolic activity to androgen activity compared to testosterone.
Mesterolone does not be converted to estrogen
Mesterolone is not a substrate for 5α-reductase because it has been reduced by 5α-reductase. Therefore, there is no enhancement in androgenic tissues such as skin, hair follicles, and prostate.
Mesterolone is not a substrate for aromatase and cannot be converted to estrogen. As a result, Mesterolone is not associated with estrogen side effects, such as gynecomastia and fluid retention.
Mesterolone is not hepatotoxic
Mesterolone is not a 17α-alkyl compound, so it has little hepatotoxicity.
Mesterolone can be taken orally
Mesterolone is not metabolized by the liver and has significant oral activity. Mesterolone is one of the few oral AAS that are either 17 alpha-alkylated or not. Mesterolone can be used in high doses or for longer periods of time depending on the individual situation.
Mesterolone increases serum free testosterone concentration
Mesterolone has a very high affinity for human serum sex hormone binding protein (SHBG), and therefore, it may replace endogenous testosterone in binding to SHBG, thereby increasing serum free testosterone concentration. Similarly, when Mesterolone is preferentially combined with SHBG, the activities of other AAS can be increased to make other AAS play their full role.
0 notes
hg-pharm · 2 years
Text
LGD 4033 Results: What should you know?
When people are using a drug, they always want to see good results. In the process of bodybuilding, in order to obtain better results, they often need the help of some drugs, so SARMs is a good choice, the full name of SARM As a selective androgen receptor modulator, it can target muscle tissue and bone tissue, helping bodybuilders increase muscle mass and improve bone mass. LGD 4033 is one of the best SARMs available for increasing muscle mass, so what are the LGD 4033 Results? Learn more through this article.
What is LGD 4033?
LGD 4033, also known as Ligandrol, is a novel non-steroidal oral selective androgen receptor modulator that was originally developed for the treatment of diseases such as muscle wasting and osteoporosis. With the development of Bodybuilding, LGD 4033 was gradually used Bodybuilders are used in bodybuilding to stimulate muscle growth and have fewer side effects than anabolic steroids. So LGD 4033 is called one of the most popular SARMs on the market today.
LGD 4033 Results: What should you know?
LGD 4033 results during use depend on many factors: the user's genetics, age, gender, quality of LGD 4033, etc., and of course training and diet plans. No two people will get the same results with LGD 4033, nor will everyone experience the same side effects.
1.LGD 4033 Results for Male
Tumblr media
For male Bodybuilders, LGD 4033's strength boost will allow you to break through your previous personal bottlenecks and enter new territory in no time. Plus, it amplifies and accelerates your muscle growth, so when male bodybuilders use LGD 4033, everything starts to happen much faster than usual.
Bodybuilders can notice a noticeable improvement in one to three weeks while training and eating right, and will notice great pumping and vascularity, increased muscle size, and some nice body reorganization.
This is a very important thing when considering LGD 4033 results: poor quality Ligandrol can produce poor quality results (not to mention worse and unintended side effects). So to get good results, you need the best quality Ligandrol.
2.LGD 4033 Results for Female
Tumblr media
It can be difficult for female bodybuilders to choose a good bodybuilding supplement, and LGD 4033 is more suitable for women than anabolic steroids.
Technically, LGD 4033 does not usually cause virilizing side effects in women, but some women have reported it.
LGD 4033 is a SARM used by female bodybuilders to build muscle mass, but it is not a substance for weight loss because LGD 4033 is not good at this area.
More hardcore female bodybuilders may feel comfortable using LGD-4033, but it is not recommended for women who have never used any other SARMbefore.
0 notes
hg-pharm · 2 years
Text
HCG vs SERM
What is a HH?
Pulsating secretion of gonadotropin-releasing hormone (GnRH) in the hypothalamus is necessary for the initiation and maintenance of the human reproductive axis.
Pulsating GnRH stimulates the biosynthesis of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn initiates endogenous testosterone production and spermatogenesis as well as systemic testosterone secretion and masculinization.
Hypogonadotropin hypogonadism (HH) results from an occasional failure of GnRH secretion or interruption of gonadotropin secretion.
The use of anabolic androgenic steroids (AAS) is a functional form that can cause HH, known as secondary acquired hypogonadotropin hypogonadism. It is diagnosed by low testosterone levels, low sperm count, or abnormal serum concentrations of LH and FSH.
There are usually two treatments for HH symptoms in this condition. Gonadotropin therapy and selective estrogen receptor modulator (SERM) therapy.
Gonadotropin therapy
In this treatment, human chorionic gonadotropin (hCG) is the first choice.
hCG acts in the same way as the pituitary LH. Stimulation of testosterone production by the testes with hCG occurs independently of exogenous hormones and/or the inhibition of HPTA that has been found. As a result, it directly stimulates endogenous testosterone production, spermatogenesis and an increase in testicular volume.
The primary goal of the first few weeks of the pct is to quickly restore testicular volume and function, so hCG is usually used during the first few weeks of the pct cycle.
SERM treatment
Selective estrogen receptor modulators, such as clomid and Nolvadex, increase pituitary secretion of LH by blocking negative estrogen feedback on HPTA. In the case of testicular atrophy, SERM may not be enough to offset the sexual condition caused by the severe imbalance of androgen to estrogen ratio following the steroid cycle. Thus, in the PCT cycle, SERM is used both as an anti-estrogen and to continue stimulating the pituitary to produce LH after hCG is discontinued.
HCG is mainly found in the pct cycle of male bodybuilder. If the inhibitory effect of AAS is not serious, HCG is generally not used. When the endogenous testosterone level of male bodybuilder is recovered, HCG is required. And SERM is a mandatory drug for male bodybuilder pct cycle.
0 notes
hg-pharm · 2 years
Text
Is LGD 4033 Safe?
LGD 4033, also known as Ligandrol, is an oral non-steroidal selective androgen receptor modulator (SARM) that binds with very high affinity to the androgen receptor (AR) and was originally developed to assist Treats muscle wasting common to cancer while helping to reduce muscle loss. When bodybuilders started taking LGD 4033, they found that they could get all the benefits they get when taking testosterone. Due to its tissue selection mechanism, it is able to target muscle tissue and bone tissue, so , LGD 4033 is gaining popularity in Bodybuilding, so Is LGD 4033 Safe? Let us know in detail through this article.
Tumblr media
Clinical studies of LGD 4033
The potential adverse effects of testosterone on the prostate led to the development of selective androgen receptor modulators that show tissue-selective activation of androgen signaling, one of which is LGD 4033. Therefore, in a study of the safety, pharmacokinetics, and effects of LGD 4033, a novel nonsteroidal oral selective androgen receptor modulator, in healthy young men, researchers evaluated 76 A 21-day study in healthy men (21-50 years) who were randomly assigned to either placebo or 0.1, 0.3, or 1.0 mg LGD 4033 per day found that LGD 4033 was well tolerated with no serious drug-related adverse events.
In the Phase 2 clinical trial, which began on November 3, 2015, the researchers tested the drug in 120 patients after hip fracture surgery. The subjects observed changes in net body weight during the 12-week test, Quality of life, safety, and pharmacokinetics all presented satisfactory results, with no drug-related serious adverse events.
Is LGD 4033 Safe?
LGD 4033 is completely safe and will not cause serious side effects after taking it. It has an anabolic ratio of 10:1 to that of testosterone, and when the two are compared, LGD 4033 shows a higher safety profile. From the appearance of LGD 4033 to the present, many studies have indicated that LGD 4033 has minimal physical effects, no drug-related serious adverse events, and increased net body weight and bone density in subjects. Although taking LGD 4033 for a long time will slightly inhibit the secretion of its own testosterone, after a period of time after the drug is stopped, the level of its own testosterone will slowly recover, and it will not affect the user himself.
0 notes
hg-pharm · 2 years
Text
SARM LGD4033:What you need to Know?
Since SARM LGD4033 was developed, researchers have conducted many studies on it, and these studies have pointed out that LGD 4033 has little toxicity to the user's body, the user has increased net body weight (muscle) and bone density, and the user When taken for a long time, the secretion of testosterone will be slightly suppressed.
Regarding its side effects, LGD 4033 does not cause any kind of hair loss or male pattern baldness like some anabolic steroids and in clinical studies the prostate size of the users was not affected. No significant side effects have been reported from users. So SARM LGD 4033 is safe.
Tumblr media
SARM LGD 4033 Benefits
1. Prevent osteoporosis
LGD 4033 has a positive effect on BMD and helps maintain bone mass by increasing periosteal bone formation while reducing muscle loss.
2. Prevent Cancer or Cachexia:
In human Cachexia, cancer, AIDS, and kidney disease, among others, are very common in patients. LGD 4033 prevents them from happening because LGD 4033 increases muscle mass and enhances muscle strength, thereby reducing the occurrence of Cachexia in the body.
3. Build muscle
Several clinical trial studies have confirmed that SARM LGD 4033 can significantly help users increase muscle mass.
4. Fat loss
SARM LGD 4033 can increase the body's metabolism, which means that the user's body will burn more fat, the user will burn more calories, and when they are converted into energy, you can create a more energy deficit, and At the same time, it protects the muscles and prevents them from being broken down during the fat loss process.
5. Increase Strength
Studies have shown that SARM LGD 4033 prevents any muscle loss that can lead to osteoporosis, it works by strengthening bone density, resulting in an increase in body strength.
SARM LGD 4033 Review
Many users of SARM LGD 4033 begin to notice significant results after a few weeks of use. The biggest change is a significant increase in the user's muscle mass. When taking only 1mg of LGD 4033, it will gain about 2.66 pounds. The higher the dose, the greater the gain, but the recommended dose should never be exceeded.
When using SARM LGD 4033 for a period of time, the user's strength and endurance will also be significantly improved, which is not only confirmed by clinical trials, but also confirmed by users who have used SARM LGD 4033.
Another thing about SARM LGD 4033 is that you get a significant change in fat loss. After using it for a period of time, the fat will be significantly reduced and it will be replaced by muscle mass.
Of course, if the SARM LGD 4033 is stacked with other SARMs, the effect will be more pronounced.
0 notes
hg-pharm · 2 years
Text
SERM vs AI - Selective estrogen receptor modulator vs aromatase inhibitor
SERM and AI are Bodybuilders used to reduce and prevent estrogen-related adverse reactions in AAS cycle.
SERM is a modulator of estrogen receptors, including tamoxifen and clomiphene.
AI is an aromatase inhibitor, including exemestane and Arimidex.
AI is divided into two types, one is an irreversible steroid inhibitor, such as exemestane, that forms a permanent binding to the aromatase complex. Another NSAID inhibitor, such as anastrozole and letrozole, inhibits aromatase through reversible competition.
The key difference between SERM vs AI is what they do to the body and how they affect oestrogen. SERM works by blocking the effects of estrogen by binding to estrogen receptors in certain body parts. SERM acts on estrogen receptors, not estrogen itself, and does not reduce serum estrogen levels.
AI works by reducing estrogen levels in the body. AI works by blocking the action of aromatase in the body, preventing the conversion of testosterone by aromatase to estrogen, thereby reducing estrogen levels in the body, increasing testosterone levels, and reducing the incidence of male atrial development.
In short, SERM prevents estrogen from acting on certain parts of the body, and AI prevents the body from synthesizing estrogen, both of which work in completely different ways.
SERM is highly effective in controlling a large number of AAS-induced estrogenic side effects. Serms like tamoxifen and Clomid help control gynecomastia because they are designed to prevent the development of estrogen receptors in breast tissue.
AI is good for water retention, while SERM is not. Therefore, the bodybuilder will choose AI for water retention issues. However, when the bodybuilder faces gynecomastia, it will need to choose SERM.
When to select SERM?
During PCT, SERM is basically chosen over AI because PCT basically addresses the problem of endogenous testosterone inhibition. AI does not address testosterone suppression, SERM does.
When to choose AI?
SARM does not aromatize, so SARM cycle does not require AI.AAS do aromatize, so AAS cycle usually requires AI. But some AAS that do not aromatize, such as DHT derivatives, do not require AI.
It can be seen from the above that the action modes of SERM vs AI are different. AI is mostly used in AAS cycle, while SERM is mostly used in PCT cycle.
0 notes
hg-pharm · 2 years
Text
SARMs PCT:Which SARMs require PCT?
In order to have a good figure, especially men, bodybuilders want steel-like abdominal muscles and arms with blood vessels, but the bad thing is that it is difficult for most people to achieve this level. However, human nature is to take shortcuts, and in the fitness industry it is not exception. SARM, also known as Selective Androgen Receptor Modulator, can help Bodybuilders get twice the result with half the effort in the process of fitness, but some SARMs will more or less inhibit the body's own gonadal axis, so after Bodybuilders use SARMs cycle, SARMs PCT is must be done. It helps restore normal levels of testosterone in Bodybuilders.
Which SARMs require PCT?
PCT is also called Post Cycle Therapy, and its main purpose is to restore your own testosterone from a suppressed state to normal levels. So which SARMs require PCT?
MK2866
If a dose of 25 mg per day is used for 12 weeks (best effect) then a course of PCT should be started after the end of the cycle. But if you complete the cycle within 8 weeks, with a daily dose of less than 20mg, you can recover naturally without the need for PCT.
LGD 4033
PCT is required after a 20 mg per day cycle for 12 weeks, even if only half the dose is used per day during the cycle. When bodybuilders are used at a dose of 20 mg per day for less than 6 weeks, PCT can be omitted.
GW 501516
GW 501516 is a PPARα agonist, in fact it is not SARMs and does not affect the gonadal axis, so PCT is not required.
YK11
PCT is required for any use of YK11, and since YK11 is methylated, liver protection is also required during the cycle of use. At the same time, the PCT must be carried out.
MK677
MK677 is an orally available growth-stimulating hormone secretion that mimics the effects of GH to stimulate endogenous hormones. It will not affect the gonadal axis, so PCT is not required in any mode of use and cycle.
SR9009
SR9009 is a REV-ErbA agonist, it is not strictly a SARM, it does not affect the gonadal axis, so PCT is not required
RAD140
RAD 140 is popular with Bodybuilders for its potent efficacy, it is also by far the most powerful SARMs, PCT is a must, no matter the method and cycle.
SARMs PCT is an issue that Bodybuilders must pay attention to. The above are some of the PCT recommendations of SARMs, and we will continue to organize them. In the PCT process of Bodybuilders, tamoxifen + clomiphene + HCG, this combination is basically a simple PCT applicable to all SARMs Cycle.
0 notes
hg-pharm · 2 years
Text
How does Clomid restore testosterone levels
Men's testosterone levels usually decline slowly as they age. From the age of 40 onwards, testosterone levels in men fall by 1% to 2% a year. However, testosterone levels can also fall rapidly due to conditions such as stroke, trauma, diabetes, liver disease, kidney disease, obesity, heart attack or medication.
Tumblr media
It's not just that people with low testosterone feel bad, have difficulty erecting, have low libido, fatigue, mood changes, sleep problems or have trouble maintaining muscle mass. It can also affect cardiovascular and bone health in middle-aged and older men.
Some men with low testosterone levels take testosterone replacement therapy to boost their overall hormone levels with exogenous supplementation of AAS. This includes injections, gels, etc. However, all exogenously replenished AAS, while increasing overall testosterone levels in men, suppress natural testosterone levels, making endogenous testosterone levels even lower. Testosterone replacement therapy can also cause testicular atrophy and fertility problems.
Clomid is not an AAS, does not suppress natural testosterone levels, and can help restore testosterone levels.
Clomid works by blocking estrogen feedback from the pituitary and hypothalamus. When exogenous AAS is supplemented, large amounts of androgens are aromatic in the body to produce estrogen, which activates a negative feedback mechanism in the hypothalamic-pituitary-testicular axis, stimulating the pituitary gland to stop producing testosterone. When Clomid blocks the effects of estrogen, estrogen's negative feedback mechanism is not triggered and the body makes more testosterone.
Therefore, not only testosterone-suppressed Bodybuilders, but also some non-Bodybuilders with low testosterone levels use Clomid to increase their testosterone levels.
Clomid has been used by a large number of people since it was approved by the FDA for medical use in 1967. A large number of in-person users have shown that Clomid is a safe compound. Side effects are usually mild, such as bloating, nausea or headaches, and few people experience more serious side effects with Clomid.
In the bodybuilder population, Clomid is the drug of choice for post-cycle repair after finishing their AAS cycle and has helped a large number of Bodybuilders restore their normal testosterone levels.
0 notes
hg-pharm · 2 years
Text
LGD 4033 Dosage :Read LGD 4033 Dosage Guide for Bodybuilding
No matter what drug is used, dosage is a user consideration, and when a new drug is used, users often consider: How much should be used each time? Learn more about LGD 4033 Dosage in this article.
Tumblr media
What is LGD 4033?
LGD 4033, also known as Ligandrol, is a non-steroidal oral selective androgen receptor modulator that targets specific androgen receptors in the body, primarily to increase muscle growth and bone density. LGD 4033 has been found in research and user-reported reviews to increase muscle mass, improve strength and endurance, and increase fat loss, making it one of the most popular SARMs for bodybuilders.
LGD 4033 provides so many benefits to Bodybuilders that proper dosage is critical. As we all know, the half-life of LGD 4033 is 24-46 hours, so Bodybuilders can take it once a day to meet your needs, whether you take it with food or on an empty stomach, it doesn't matter if you take it during the day or night, as long as you keep taking it regularly and quantitatively every day.
What is LGD 4033 Dosage?
For male Bodybuilders, a reasonable dose of LGD 4033 is 10 mg per day for 8 to 12 weeks.
For female Bodybuilders, a reasonable dose of LGD 4033 is 5 mg per day for 8 to 12 weeks.
When in the Bulking Cycle, bodybuilders should maintain a protein-rich diet and higher calorie intake while maintaining the above doses.
When in the Cutting Cycle, in order to achieve the best fat reduction effect, Bodybuilders can also try SARM stacking while guaranteeing the daily dose of LGD 4033 to achieve the best fat reduction effect. The recommended stacking is GW 501516, S 4 and LGD 4033 was used concurrently for 8 weeks.
Bodybuilders can also choose to use LGD 4033 when in the Recomping Cycle, as LGD 4033 is one of the best SARMs for Recomping, which can help Bodybuilders increase lean body mass and fat loss.
The right dose of SARM LGD 4033 is non-irritating to the liver and does not cause side effects such as high blood pressure, high cholesterol and prostate problems. Compared with other SARMs, LGD 4033 is more effective in increasing lean muscle mass, increasing bone density and reducing fat.
0 notes
hg-pharm · 2 years
Text
Why does Bodybuilder run pct cycle
Pct cycle or post-cycle treatment refers to the protocol followed by the bodybuilder after completing the anabolic steroid (AAS) cycle.
Although AAS cycle can provide benefits such as amazing muscle growth, AAS can also take a toll on bodybuilder's physical health, especially on testosterone levels. When bodybuilder takes AAS, these AAS drugs provide a large dose of testosterone to the body after they are released in the body. High levels of exogenous testosterone in the body trick the brain into thinking that the body has enough, gradually reducing or even stopping the production of endogenous testosterone. When the AAS cycle is complete, the intake of exogenous AAS is abruptly stopped, and endogenous testosterone production does not keep up, leaving the body in a state of low testosterone.
Tumblr media
This is when the brain realizes that testosterone levels are low and needs to increase its production. But the process is slow and can take months to years to restore normal testosterone levels. At the same time, the body is experiencing the effects of low testosterone levels, such as decreased energy and libido, and decreased muscle mass. A sudden drop in androgen levels can leave a full person with a sudden feeling of exhaustion and, in severe cases, psychological distress such as depression. Post-cycle therapy (pct) can help speed up this process and restore endogenous testosterone levels as quickly as possible because it increases gonadotropin production.
Clomid promotes the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which helps restore testosterone levels.
A large amount of AAS is aromatized by aromatase in the body and produces a large amount of estrogen, which will bring some estrogen side effects to the male bodybuilder, such as gynecomastia and water retention. SERM Clomid regulates estrogen levels to avoid possible estrogen side effects.
Male Bodybuilders must undergo a pct cycle after AAS cycle to restore their testosterone levels and eliminate estrogen side effects. A reasonable pct cycle is essential for male bodybuilder. Clomid will also be used with Nolvadex and hCG for pct cycle in bodybuilder.
0 notes