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Career as a Dermatologist – How to Become, Courses, Job Profile, Salary & Scope

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Cycle of Malaria

Malaria has remained one of the most severe growing diseases for years, affecting millions of people worldwide. 

Also called the Roman Fever, the disease is often caused by various microorganisms called Plasmodium. 

If you are a medical student, you need to understand the life cycle of Plasmodium, the parasite responsible for humans who have been battling for years. Let's know the cycle of malaria.

What exactly is Plasmodium Protozoa?

Plasmodium represents the genus parasitic protozoa responsible for the deadly disease called malaria. These microscopic organisms go through a complicated life cycle involving two hosts: humans and mosquitoes. 

Malaria symptoms include fever, chills, headaches, and fatigue. In severe cases, the symptoms can worsen, resulting in organ failure, coma, and even death. 

Different types of Plasmodium

There are different types of Plasmodium species affecting humans such as:

P. vivax

P. falciparum

P. ovale

P. malariae

P. knowlesi

Now let's learn more about malaria through its life cycle. 

The basic life cycle of malaria

The Sporogonic Cycle (the mosquito phase):

The sporogonic cycle begins when a female Anopheles mosquito feeds on malaria-infected blood, harboring male and female gametocytes. Within the mosquito's gut, gametocytes develop into gametes: male gametes fertilize female ones to give birth to zygotes. This zygote then matures to produce a motile ookinete that invades the outer gut wall, developing into an oocyst within which the parasites multiply quickly. Thousands of sporozoites spill out of the oocyst when they burst open and migrate to salivary glands in the mosquito. When the next human is bitten, these sporozoites penetrate the skin, eventually entering the bloodstream and travelling into the liver, which initiates the parasite cycle in the human.

 The Asexual Cycle (the human phase):

After the mosquito bites the human, the sporozoites enter the bloodstream. After that, they move straight to the liver of the human body. Once inside the liver, they invade hepatocytes and undertake a phase of asexual multiplication. The sporozoite matures into schizonts in these cells, bursting with thousands of merozoites. At the end of the multiplication process, the schizonts explode, releasing merozoites into the bloodstream. This is where the liver phase ends, and the symptomatic blood phase starts. 

(Erythrocytic Cycle) (the human blood phase):

Released from the liver, merozoites enter the bloodstream and invade RBCs. Once inside the RBCs, they develop through the following stages: ring form, trophozoites, and schizont. Eventually, the schizont matures and divides to cause rupture of the RBC, releasing new merozoites, which will further infect RBCs. This cycle of invasion, multiplication, and RBC lysis leads to various symptoms, such as fever, chills, etc. While feeding, these gametocytes are transferred to another mosquito, which closes the transmission cycle.

Thus, we hope you have now easily understood the malaria life cycle from these life stages.

Conclusion

With such a complex life cycle of malaria, we hope you have found this blog post helpful in understanding how the disease spreads and leads to illness. 

To learn more about this, or if you want to access more resources, visit DigiNerve now!

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Preparing for the USMLE: Study Tips and Resources

As you move towards becoming a licensed doctor and obtaining your exceptional MD degree, you need to do a few essential things that will help you understand where you stand and how much knowledge you possess.

The United States Medical Licensing Examination (USMLE), which must be passed by all US physicians to be licensed, is one such checkpoint. Since the exam goes through different phases, Step 1, Step 2 and Step 3, you must prepare and pass the examination with flying colours.

Therefore, we decided to share some tips so that whenever you prepare for this exam, you’ll have USMLE resources in your hand. 

Let's get started. 

USMLE Preparation: Tips to consider

When preparing a plan for the USMLE exam, you must consider the following tips:

Understand your learning style: Everyone learns in different ways. Some students understand better through pictures and charts, while others like to listen to audio and video lectures. So, it's essential to understand your learning style before you start studying. 

Look at your options wisely: Before spending money on any resource, consider it carefully. Look for reviews and feedback from other students and figure out which option they are choosing to opt for. Don’t just fall for shiny ads; research for the best choice by looking at resources with a 100% success rate.

Opt in engaging courses: The textbooks may not give you precisely what you want. That is why highly engaging and interactive courses include engagement activities, AI chatbots, and other attractive features that make learning more fun and easy.

Below, we have provided a whole section on one such course. Have a look and find out what it is about. 

Join the e-learning course by DigiNerve Now!

Are you gearing up for your final MD examinations? If so, you might want to check out this amazing course by DigiNerve! Created by the team of specialised doctors like Dr. Jyotirmoy Pal and Dr. Shashank R Joshi, along with the input from over 200 experts from this field. 

The course is perfect for those who want a structured learning experience that can assist them in addressing the gaps in their clinical skills. 

Below are the brief features of this Medicine MD course:

The case-based approach allows students to improve their clinical skills as these address several concepts which are not covered in textbooks. 

The course further includes self-assessment and multiple-choice questions that can help you understand how much you are aware of the concepts.

Conventional methods of learning are boring, so the 2D animations in this course make even the boring concepts easy to learn. 

There are well-illustrated lecture notes that are also mentioned at the end of the topic, so you save time making notes.

Engagement activities like regular chat shows, journal clubs and recent updates make learning fun and interactive. 

So, what sets this course apart? It’s the unique blend of evidence-based learning, expert guidance and real-world clinical experience. 

Conclusion

Are you ready to take your MD prep to the next level? Don’t miss out on this opportunity to learn from the best!  Click here to enroll now and start your journey towards MD success.

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