nsft-spin

[nsft-spin]

mm fulled of eggs

[nsft-spin]

“As a biologist, the terms biological woman and man don’t make any sense to me” okay then you’re an idiot and a terrible biologist. I swear to god, morons like you only become biologists just so you can hold it over others, when in reality, if biology deniers like you can become biologists, then being one really doesn’t mean much anyway. But this probably just gave an autogynophile like you a boner to read, anyway.

Oh fun! Haven't gotten one of these in a while. Disregarding the fact that you somehow think the qualification for being a biologist entirely hinges on defining womanhood, I do need to ask some clarification. I know I'm feeding the trolls here, but here we go: does your definition of "biological woman" mean:

Sociological woman? Eh, context dependent, I'm not fully out of the closet, but oftentimes, I am and present femme. So let's call that one 50/50.

Psychological woman? Because I am one.

Neurological woman? Because I am one [1].

Physical woman? My soft tissue redistribution is handling that well.

Hormonal woman? My blood tests are within cis female ranges.

Transcriptional woman? As a signalling molecule, the downstream effects of estrogen have broad transcriptional effects, completely changing the profile of gene expression and functional genomics of my cells. [2]

Genetic woman? I mean, see my above point- as far as my genes that are actually active, I have all of the same transcripts being produced, controlling which genes are expressed.

Karyotypic woman? I actually have a few signs pre-HRT that might point to a non-XY chromosome pair, but I haven't had a karyotype. We'll put that down as unknown. And hell, even if its XY, there's plenty of cis women who are karyotypically XY, with suppressed sry or complete androgen insensitivity. Interestingly enough, a completely androgen insesitive woman can go her whole life without knowing- and functionally, is very similar to a trans woman, actually. Fancy that. [3]

Reproductive woman? I can't produce an egg cell, but neither can significant fractions of cis women. Also, this is all gonna change soon, which is fun. [4]

There's also a lot of understudied aspects to the biology of HRT and even pre-HRT that are emerging, largely demonstrating widespread cellular and genetic remodeling of trans individuals undergoing hormone therapy. The field is a bit behind due to constant political pressure to revoke funding, but a lot of the results are extremely exciting in both testosterone and estrogen hormone therapies. I'm sure that, as a self professed biology As someone who presumably has a lot of expertise in biology, I'm assuming that you're aware of all of this cutting edge research, and are keeping up with modern papers, including but not limited to these cool findings:

Trans men on HRT exhibit significant genetic and transcriptional changes that make them biochemically male. [5][6]. It's a good hypothesis that the same happens with estrogen treatment, but those studies don't exist yet- I'm sure you're reserving judgment until more publications exist, of course.

Trans men on HRT develop male cell types and tissues. [7]

Trans women experience muscular and blood cell changes that align with cis women moreso than cis men [8]

And many, many more! This is an exciting, underserved, and groundbreaking field of research, and I'm sure you're keeping up with the latest in scientific journals about it.

I'm sure, of course, that you understand that it becomes impossible to draw a distinct line anywhere in here, and that words like "woman" are shorthand for the myriad of traits that invisibly synthesize in our mind and in society to represent a concept? I'm sure you understand that science is fundamentally descriptive, not prescriptive? I'm sure that you understand that these findings, while really cool and interesting, actually don't mean jack shit about what the word "woman" means or not?

As someone who is the ultimate decider in what a biologist is, I'm sure you know that bioessentiallism is a childish mindset that completely ignores and disregards the constantly changing, dynamic nature of biological systems, something that extends well beyond biological sex and its relation to gender.

I'm sure that also, that you understand that beyond just this, that the role of science in society is to advise how to achieve our moral principles, not create moral principles in themselves. And I'm sure that understanding means you know that trans affirming healthcare and supportive societal treatment leads to reduced mortality and increased happiness for everyone, right?

So great to talk to someone who is surely a scientist on this. You are a biologist, if you're talking like this, I assume? I assume you're not going to spit complete misreadings of scientific language from the background sections of these papers that only reveal you've never read a scientific paper in your life if you're thinking this way? I assume you have experience interpreting data like this?

Also, imagining my genitalia while writing this? Ew. Please stop projecting your fetishes into my inbox.

Works cited:

Kurth F, Gaser C, Sánchez FJ, Luders E. Brain Sex in Transgender Women Is Shifted towards Gender Identity. J Clin Med. 2022 Mar 13;11(6):1582. doi: 10.3390/jcm11061582. PMID: 35329908; PMCID: PMC8955456.

Fuentes N, Silveyra P. Estrogen receptor signaling mechanisms. Adv Protein Chem Struct Biol. 2019;116:135-170. doi: 10.1016/bs.apcsb.2019.01.001. Epub 2019 Feb 4. PMID: 31036290; PMCID: PMC6533072.

Gottlieb B, Trifiro MA. Androgen Insensitivity Syndrome. 1999 Mar 24 [Updated 2017 May 11]. In: Adam MP, Feldman J, Mirzaa GM, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2024. Available from: https://www.ncbi.nlm.nih.gov/books/NBK1429/

Murakami, K., Hamazaki, N., Hamada, N. et al. Generation of functional oocytes from male mice in vitro. Nature 615, 900–906 (2023). https://doi.org/10.1038/s41586-023-05834-x

Pallotti F, Senofonte G, Konstantinidou F, Di Chiano S, Faja F, Rizzo F, Cargnelutti F, Krausz C, Paoli D, Lenzi A, Stuppia L, Gatta V, Lombardo F. Epigenetic Effects of Gender-Affirming Hormone Treatment: A Pilot Study of the ESR2 Promoter's Methylation in AFAB People. Biomedicines. 2022 Feb 16;10(2):459. doi: 10.3390/biomedicines10020459. PMID: 35203670; PMCID: PMC8962414.

Florian Raths, Mehran Karimzadeh, Nathan Ing, Andrew Martinez, Yoona Yang, Ying Qu, Tian-Yu Lee, Brianna Mulligan, Suzanne Devkota, Wayne T. Tilley, Theresa E. Hickey, Bo Wang, Armando E. Giuliano, Shikha Bose, Hani Goodarzi, Edward C. Ray, Xiaojiang Cui, Simon R.V. Knott, The molecular consequences of androgen activity in the human breast, Cell Genomics, Volume 3, Issue 3, 2023, 100272, ISSN 2666-979X, https://doi.org/10.1016/j.xgen.2023.100272. (https://www.sciencedirect.com/science/article/pii/S2666979X23000320)

Xu R, Diamond DA, Borer JG, Estrada C, Yu R, Anderson WJ, Vargas SO. Prostatic metaplasia of the vagina in transmasculine individuals. World J Urol. 2022 Mar;40(3):849-855. doi: 10.1007/s00345-021-03907-y. Epub 2022 Jan 16. PMID: 35034167.

Harper J, O'Donnell E, Sorouri Khorashad B, McDermott H, Witcomb GL. How does hormone transition in transgender women change body composition, muscle strength and haemoglobin? Systematic review with a focus on the implications for sport participation. Br J Sports Med. 2021 Aug;55(15):865-872. doi: 10.1136/bjsports-2020-103106. Epub 2021 Mar 1. PMID: 33648944; PMCID: PMC8311086.

[nsft-spin]

*horny guy voice* someone pls cut me open and dig around in my guts

[nsft-spin]

I went to go get mail today through the Campus mail center, and I got two packages instead of the one I thought I had. I was like "yipee! More things!" As the person handing me my mail scanned the packages and my student ID. She made a mildly intrigued "hmm" noise and handed me the packages. When I looked at the second package (the one she made the noise at) I fuckin- bro. It was a set of urethral dilators for my fucjing sounding fetish. And it was labeled as such on the package.

I was so ready to disintegrate istg. She fucking saw my fetish stuff - hopefully she thinks I'm just a nursing major 😭😭

[nsft-spin]

the concept of public transport is so sexual OK you "got off" the bus?

[nsft-spin]

I do think it's worth "examining your kinks," at the very least because if you can find an underlying theme you can use it to find other, stranger kinks. Broaden your horizons

[nsft-spin]

Need a mad scientist to kidnap me as a test subject, fascinated by the long term effects of testosterone on a pussy, so they grab me to examine and experiment on

Need to be strapped to a lab table with gloved fingers twisting and pulling my tdick, asking me to rate my pain on a scale of 1-10 and ignoring my cries of “ten ten ten please let go.” want them to hold a vibrator to it and randomly select the speeds for a better sample, recording the time it takes for me to cum over and over. After I’m fucked out and overstimulated, they can take a break by using my mouth to get off, leaving my cunt free to test how long I can take a fucking machine pounding into me before I pass out

[nsft-spin]

Hngghhh- thinking about being used by a doctor. Being tied down on a metal exam table. Hearing the snap of him putting on his gloves. Feeling his cold fingers run over my sensitive skin. He was nice enough to blindfold me because of how bright the lights are. He takes his time performing each and every one of his little tests. How many times can he bring me to the edge of orgasm until I break with frustration? How much can he fuck my hole with bigger and bigger tools until it's too much? How long can he keep control of himself until he breaks, going against his doctor code and fucking me full?

[nsft-spin]

oh to be the research assistant to a monster sexologist who rambles on about their scientific findings about the breeding habits of the monsters mounting me

[nsft-spin]

hmm how about you lock me in a cage w a fuck machine inside of me and go out to run some errands and leave me just like that? coming home after 10 hours just to find me passed out and still cumming

[nsft-spin]

I need to get my pussy railed by a woman with an ovipositor. Bending me over and fucking silicone eggs into my cunt. Fingerfucking me and pushing them in as far as they can go. Watching or even filming me as I push them out and calling me a good pet the whole time. Shoving her genitals into my face as a reward and thrusting into my mouth. God, I would give anything💕

[nsft-spin]

[nsft-spin]

THIS IS THE FUTURE THE LEFT WANTS

[nsft-spin]

I want dirty dungeons and dragons.

I want real seduction instead of rolls. Clothing removal as penalty for failed checks. Cockwarming in exchange for better loot. Vibrators controlled by the DM. A whole room full of horny players squirming in their seats trying to remember simple addition.

I want ‘The BBEG is casting a charm spell- stare into this spiral and edge yourself for the rest of combat.’

And

‘You failed your wisdom save and are now the Naga’s slave- now take off your panties and sit on the battle board, she wants to make use of her new toy’

[nsft-spin]

The thought of waking up to someone fucking roughly into you and proceed to go harder when they realize you are awake just sends me crazy

[nsft-spin]

Hey, hey. Don't be sad. Women spitroasting you until you can't think, okay?

[nsft-spin]

Listen. I do love weird looking monster cocks as much as the next guy, but I genuinely barely see any love for bizarre vagina biology on monsters. Whenever I see monster cunt it's always basically just human, and what's with that?

Hear me out. Here are some suggestions:

Insect monsters whose chitinous underbellies you have to rub and caress to get to their slits/gonopores.

Transmasc werewolves whose bottom growth is exagerrated while transformed, allowing for easy penetration. Knotted tdicks anyone?

Monsters who have claspers in their cunts to keep you locked inside of them while you cum.

Monsters whose wetness has an aphrodisiac quality, making it hard to think of anything but keeping your face and tongue buried inside of them to get more.

Reptile monsters with hemiclitori to make pleasure even more intense as you eat them out.

Monsters with vaginal canals they can restrict and shift around independently, allowing them to form fit themselves perfectly to your fingers or cock.

Robots with slits that vibrate as you grind against or fuck them.

Hyena monster women with pseudo-penises.

PUSSY TENTACLES!!

Idk man like monster cocks are neat but I need to eat out weird monster pussy okay?