Since Megamind is becoming more appreciated as the masterpiece of cinema it is, here are my favorite lines in no particular order:
Metroman’s mom: “Oh, wow! A baby!”
Metroman’s dad: “Ah yes, I saw it and thought of you.”
Metroman’s mom: “Our baby is flying!”
Metroman’s dad: “Yes, yes, only the best for you.”
Megamind: “He would win some. I would almost win others.”
Roxanne: “His heart is an ocean, inside another ocean.”
Roxanne: “Is there some kind of nerdy super-villain website where you get tesla coils and blinky dials?”
Minion: “Actually, most of it comes from an outlet store in-”
Megamind: “Don’t answer that!” *
Minion: *whispers* “Romania”
Megamind: “Oh I’m shaking in my custom baby seal leather boots!”
Minion: “It’s warming up.”
Megamind: “The sun is warming up?!”
Roxanne: “Can someone stamp my frequent kidnapping card?”
Megamind: *laughs* “You of all people know we discontinued that promotion!”
Megamind: “Not now Minion, I’m in a heated existential discussion with this dead-eyed plastic desk toy.”
Roxanne @ Metroman: “Without you, evil is running rampant through the streets!”
Megamind: “I’m so tired of running rampant through the streets.”
Minion: “Good luck on your date!”
Megamind:“I will!”
Minion: “That doesn’t make any sense!”
Megamind: “I know!”
Megamind: “Now it’s time for some witty back and forth banter! You go first!”
Titan: “AHHHHH”
Megamind: “Okay, look, I’m not sure where to go with that!”
Roxxane @ Metroman: “You left us in the hands of….him! No offense.”
Megamind: “No, no, I’m with you.”
Megamind: “Get back you savages!”
Roxanne: “Sorry! Sorry! He’s just not used to positive feedback!”