#BIOENGINEER.ORG

[biglisbonnews]

Transport, domestic activities and agriculture are the main contributors to air pollution related mortality in European cities Air pollution is the largest environmental cause of death. Now, a study led by the Barcelona Institute for Global Health (ISGlobal), a centre supported by the “la Caixa” Foundation, has estimated which sources contribute most to the mortality associated with two air pollutants – PM2.5 and NO2 – in 857 European cities. Credit: ISGlobal Air […] https://bioengineer.org/transport-domestic-activities-and-agriculture-are-the-main-contributors-to-air-pollution-related-mortality-in-european-cities/

[perfectlydangerousarbiter]

Science Media Notes UMaine's Role in Study of Early Hunting in North America - UMaine News

Science Media Notes UMaine’s Role in Study of Early Hunting in North America – UMaine News

science daily, scienmag and Bioengineer.org noted that Brian McGill, a professor of biological sciences in the University of Maine School of Biology and Ecology, co-authored a University of Nebraska-Lincoln-led study of how early hunting homogenized mammalian communities in North America. The researchers conducted an analysis of 8,831 fossils representing 365 species of mammals from 366 sites…

[biotechworld]

Estonian Biobnk launches a large study on mental health genetics

Estonian Biobnk launches a large study on mental health genetics

Credit: University of Tartu Nearly every second individual is affected by a mental health problem in their lifetime, but the exact mechanisms causing these problems remain unclear. To bring more clarity to the field of mental health, the Estonian Biobank at the University of Tartu has launched a large study, which is unique in the world. The results of this study will contribute towards the…

[bioengineered]

Deep in the weeds: Using eDNA sequencing to survey pondweed diversity https://bioengineer.org/deep-in-the-weeds-using-edna-sequencing-to-survey-pondweed-diversity/

[biotechworld]

Prehistoric killing machine exposed

Prehistoric killing machine exposed

Previously thought of as heavy, slow and sluggish, the 260-million-year-old predator, Anteosaurus, was a ferocious hunter-killer Credit: Alex Bernardini (@SimplexPaleo) Judging by its massive, bone-crushing teeth, gigantic skull and powerful jaw, there is no doubt that the Anteosaurus, a premammalian reptile that roamed the African continent 265 to 260 million years ago – during a period known…

[biotechworld]

Oncotarget: Phase 1 study of Z-Endoxifen in patients with solid tumors

Oncotarget: Phase 1 study of Z-Endoxifen in patients with solid tumors

The Oncotarget article provides evidence that antitumor activity and prolonged stable disease are achieved with Z-endoxifen despite prior tamoxifen therapy. Credit: Correspondence to – Alice P. Chen – chenali@mail.nih.gov Oncotarget published “Phase 1 study of Z-Endoxifen in patients with advanced gynecologic, desmoid, and hormone receptor-positive solid tumors” which reported that Z-endoxifen…

[biotechworld]

Electrochemical synthesis of formate from CO2 using a Sn/reduced graphene oxide catalyst

Electrochemical synthesis of formate from CO2 using a Sn/reduced graphene oxide catalyst

Credit: Kanazawa University [Background] Decreasing the emission and efficient utilization (fixation) of carbon dioxide (CO2) are worldwide issues to prevent global warming. Promotion of the use of renewable energy is effective in reducing CO2 emissions. However, since there are large time-dependent fluctuations and large regional differences in renewable energy production, it is necessary to…

[biotechworld]

Oncotarget: Hispanic Chronic myelomonocytic leukemia patients

Oncotarget: Hispanic Chronic myelomonocytic leukemia patients

This Oncotarget study had significantly lower mutation rates in ASXL1 and SETBP1, and a higher rate of muTET2/wtASXL1 Credit: Correspondence to – Jie-Gen Jiang – jj688@njms.rutgers.edu Oncotarget published “Cytogenetic and molecular landscape and its potential clinical significance in Hispanic CMML patients from Puerto Rico” which reported that one hundred and eleven Hispanic CMML patients from…

[biotechworld]

A project by Russian scientists will help create capsules for targeted drug delivery

A project by Russian scientists will help create capsules for targeted drug delivery

Credit: Authors of the article from ITMO Scientists from MIPT and ITMO University and their colleagues have studied the formation and growth of crystals from simple organic molecules into large associations. These experiments will help create capsules for targeted drug delivery to specific tissues in the human body. The scientific paper was published in the journal Crystal Growth &…

[biotechworld]

Oncotarget: Predictors of immunotherapy benefit in Merkel cell carcinoma

Oncotarget: Predictors of immunotherapy benefit in Merkel cell carcinoma

Dr. Glenn J. Hanna from CCR/NCI in Bethesda, MD as well as The Dana-Farber Cancer Institute in Boston Massachusetts said, “Merkel cell carcinoma (MCC) is a relatively rare cancer, with roughly 400 cases per 100,000 persons each year in the United States” Credit: Correspondence to – Glenn J. Hanna – glenn_hanna@dfci.harvard.edu Oncotarget published “Predictors of immunotherapy benefit in Merkel…

[biotechworld]

Oncotarget: Ibuprofen disrupts protein complex in colorectal cells

Oncotarget: Ibuprofen disrupts protein complex in colorectal cells

The Oncotarget data shed new light on the biochemical mechanisms behind ibuprofen’s action on alternative spliced RAC1B and may support its use in personalized approaches to CRC therapy or chemoprevention regimens. Credit: Correspondence to – Peter Jordan – peter.jordan@insa.min-saude.pt Oncotarget published “Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of…

[biotechworld]

Oncotarget: Quantitative proteome profiling stratifies fibroepithelial lesions of the breast

Oncotarget: Quantitative proteome profiling stratifies fibroepithelial lesions of the breast

The present Oncotarget work shed light on a brief mechanistic framework of PTs aggressive nature and present potential biomarkers to differentiate overlapping FELs that would be of practical utility in augmenting existing diagnosis and disease management Credit: Correspondence to – Lekha Dinesh Kumar – lekha@ccmb.res.in and Prashant Kumar – prashant@ibioinformatics.org Oncotarget published…

[biotechworld]

Oncotarget: Genomic and neoantigen evolution in head and neck squamous cell carcinoma

Oncotarget: Genomic and neoantigen evolution in head and neck squamous cell carcinoma

In this Oncotarget study, the authors characterized the mutational and neoantigen burden between primary and first recurrence tumors in 23 patients with HNSCC Credit: Correspondence to – Brian A. Van Tine – bvantine@wustl.edu Oncotarget published “Genomic and neoantigen evolution from primary tumor to first metastases in head and neck squamous cell carcinoma” which reported that prior work has…

[biotechworld]

‘Time lost is brain lost’

‘Time lost is brain lost’

Study finds mobile stroke units improve outcomes and lessen rates of disability in stroke patients. Credit: UCLA Health A new study involving UCLA researchers finds that mobile stroke units (MSUs) – state-of-the-art ambulances built to provide stroke patients with emergency neurological diagnosis and treatment prior to hospital arrival — improve patient outcomes and lessen the chance for…

[biotechworld]

Semiconductor nanogrooves enhanced broad spectral band mmW and THz detection

Semiconductor nanogrooves enhanced broad spectral band mmW and THz detection

Credit: by Jinchao Tong, Fei Suo, Tianning Zhang, Zhiming Huang, Junhao Chu and Dao Hua Zhang Millimetre and terahertz wave detectors have a wide range of applications in areas such as communications, security, biological diagnosis, spectroscopy, and remote sensing. They are the components that can transform light information loaded by long-wavelength millimetre and terahertz waves into…

[biotechworld]

Crystal structure prediction of multi-elements random alloy

Crystal structure prediction of multi-elements random alloy

Credit: POSTECH Alchemy, which attempted to turn cheap metals such as lead and copper into gold, has not yet succeeded. However, with the development of alloys in which two or three auxiliary elements are mixed with the best elements of the times, modern alchemy can produce high-tech metal materials with high strength, such as high entropy alloys. Now, together with artificial intelligence, the…