#Cornus officinalis Sieb. et Zucc.

[21miki]

Apeace J.D’s instagram seoul,KOREA

[maoyeamh]

[markunsan]

Cornus officinalis

[yopparainokobito]

Sanshuyu,Kyoto Botanical Gardens,Kyoto by Yopparaino Kobito

[healthtimetaylor]

Undescribed morroniside-like secoiridoid diglycosides with α-glucosidase inhibitory activity from Corni Fructus.

PMID:  Phytochemistry. 2020 Jan 3 ;171:112232. Epub 2020 Jan 3. PMID: 31911266 Abstract Title:  Undescribed morroniside-like secoiridoid diglycosides withα-glucosidase inhibitory activity from Corni Fructus. Abstract:  Corni Fructus, also known as the fruit of Cornus officinalis Sieb. et Zucc., has long been used as a traditional Chinese medicine and is widely consumed as a nutritional food in the form of function drink and wine. Recently, Corni Fructus has attracted considerable interest because of its anti-diabetic effects. A systematic phytochemical investigation of Corni Fructus was performed to find anti-diabetic components, which led to the isolation of 10 unreported iridoid glycosides, cornusdiglycosides A-J (1-8, 9a/9b and 10a/10b). Their chemical structures were determined through spectroscopic analysis (ultraviolet [UV], infrared [IR], high-resolution electrospray ionisation mass spectroscopy [HRESIMS], one-dimensional [1D] and two-dimensional [2D] nuclear magnetic resonance [NMR]). Such morroniside-type diglycosides were first reported from natural sources, and all isolates were evaluated forα-glucosidase inhibitory activity. The results showed that all compounds (1-10) exhibited α-glucosidase (from Saccharomyces cerevisiae) inhibitory activities with ICvalues ranging from 78.9 ± 4.09 to 162.2 ± 9.17 μM, whereas acarbose, the positive control, displayed α-glucosidase inhibitory activity with ICvalue of 118.9 ± 7.89 μM.

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[krs955]

san-shuyu, Japanese cornel or Japanese cornelian cherry or Cornelian cherries, (Cornus officinalis Sieb. et Zucc., サンシュユ, 山茱萸, ハルコガネバナ, アキサンゴ, ヤマグミ), ミズキ科ミズキ属.

[yopparainokobito]

Sanshuyu,Kitano-tenmangu,Kyoto by Yopparaino Kobito