#Global Nucleic Acid Isolation and Purification Market size

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Nucleic Acid Isolation and Purification Market Size, Key Vendors, Growth Rate, Drivers, and Volume & Forecast Report to 2024-2032

The global nucleic acid isolation and purification market is poised for significant expansion, with its market size estimated to grow from USD 6.60 billion in 2023 to an impressive USD 16.38 billion by 2032. This growth reflects a compound annual growth rate (CAGR) of 11.18% during the forecast period from 2024 to 2032, driven by advancements in molecular biology research, diagnostics, and biotechnological innovations.

Nucleic acid isolation and purification are critical steps in molecular biology and genetic research, enabling the extraction and purification of DNA or RNA from various biological samples. These processes are essential for a wide range of applications, including diagnostics, drug discovery, genomic studies, and the development of personalized medicine.

Key Market Drivers

Advancements in Genomic Research and Precision Medicine: The growing emphasis on genomics, personalized medicine, and gene-based therapies is a significant driver of the nucleic acid isolation and purification market. As scientists explore the human genome for disease markers and potential treatments, the demand for efficient and reliable nucleic acid extraction tools has surged. These processes play a crucial role in understanding genetic diseases, identifying biomarkers, and developing targeted therapies.

Expanding Use in Diagnostics and Infectious Disease Research: The nucleic acid isolation and purification market saw a notable boost during the COVID-19 pandemic, with its application in viral detection and monitoring through PCR (polymerase chain reaction) and other molecular diagnostic techniques. As the world continues to focus on infectious disease control, the need for accurate diagnostic tests, including those for emerging pathogens, remains critical. Nucleic acid isolation is the foundation for such molecular diagnostics, driving growth in this market segment.

Growing Demand in Biotechnology and Pharmaceutical Industries: In addition to diagnostics, biotechnology and pharmaceutical companies are leveraging nucleic acid isolation technologies for drug development and bioproduction. With increased funding for research into biologics, gene therapies, and vaccines, the pharmaceutical sector’s reliance on these processes is expected to continue growing. This demand is particularly significant for companies focused on RNA-based therapies, mRNA vaccines, and CRISPR gene-editing technologies.

Technological Innovations in Isolation and Purification Techniques: Continuous advancements in nucleic acid extraction technologies are transforming the market. Automated systems, high-throughput solutions, and faster, more efficient isolation kits are being developed to meet the needs of researchers and clinicians. These innovations not only reduce manual labor and errors but also improve reproducibility and sample integrity, making nucleic acid isolation and purification more accessible across various fields of study.

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Challenges and Opportunities

The nucleic acid isolation and purification market faces several challenges, including the high cost of automated systems and consumables, particularly for smaller research labs and healthcare institutions. However, the benefits of increased efficiency, accuracy, and scalability are driving wider adoption, while ongoing research into cost-effective solutions presents opportunities for market expansion.

Moreover, the rise of next-generation sequencing (NGS) and its application in cancer research, genetic testing, and rare disease studies presents a growing opportunity for the market. As sequencing technologies advance and become more affordable, the demand for high-quality nucleic acid extraction methods will intensify.

Regional Insights

North America currently holds the largest share of the nucleic acid isolation and purification market, driven by the region’s strong focus on research and development, particularly in the areas of genomics, drug discovery, and molecular diagnostics. The United States, with its leading research institutions and biopharmaceutical companies, is a key contributor to this market growth.

Europe follows closely, with increasing investments in biotechnology and genomics research. The Asia-Pacific region is expected to witness the highest growth rate during the forecast period, driven by rising healthcare infrastructure, growing biotech industries, and increased research funding in countries such as China, India, and Japan.

Future Outlook

As genomic research, molecular diagnostics, and precision medicine continue to advance, the nucleic acid isolation and purification market is expected to see sustained growth. The increasing focus on personalized healthcare, gene-based treatments, and the use of nucleic acid technologies in various therapeutic applications will drive market expansion in the coming years. Furthermore, the growing prevalence of cancer, infectious diseases, and genetic disorders will fuel demand for nucleic acid extraction technologies for research and clinical applications.

In conclusion, the nucleic acid isolation and purification market is set for robust growth, with its value projected to rise from USD 6.60 billion in 2023 to USD 16.38 billion by 2032, at a CAGR of 11.18%. The increasing application of nucleic acid technologies in diagnostics, drug discovery, and genomics will continue to drive market dynamics, making this a vital area of growth within the life sciences and healthcare sectors.

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DNA and RNA Sample Preparation Market is Estimated to Witness High Growth Owing to Increasing Adoption

The DNA and RNA sample preparation market involves processes associated with isolation, extraction, purification and quantification of nucleic acids DNA and RNA from various sources like tissues, blood, sperm, cells etc. for downstream applications in genomics, molecular diagnostics, personalized medicine and others. The sample preparation is a critical and initial step before conducting various genomic tests including Next Generation Sequencing, polymerase chain reaction and other assays. Growing awareness and adoption of precision medicine and genetic/molecular testing is driving demand for efficient nucleic acid isolation and downstream analysis.

The Global DNA and RNA Sample Preparation Market is estimated to be valued at US$ 2262.46 Mn in 2024 and is expected to exhibit a CAGR of 5.8% over the forecast period 2024 To 2031. Key Takeaways Key players operating in the DNA and RNA sample preparation are Agilent Technologies, Inc., Becton, Dickinson and Company, Bio-Rad Laboratories Inc., DiaSorin S.p.A, F. Hoffmann-La Roche, Miroculus, Inc., Illumina, Inc., PerkinElmer, Inc., QIAGEN, Sigma Aldrich Corp., Tecan Group AG, and Thermo Fisher Scientific, Inc. Growing prominence of personalized medicine is creating opportunities for development of new sample preparation methods and kits which can extract nucleic acids from various types of samples. Rising incidence of chronic and infectious diseases worldwide is increasing diagnostic testing which will propel sample preparation market growth. Global expansion of key market players through acquisitions and partnerships with regional diagnostic labs and research institutes will further augment market revenues. Market Drivers Increasing funding for Genomic and genetic research from government bodies as well as private sector is one of the key factors driving the DNA and RNA Sample Preparation Market Size. Government initiatives aimed at large scale population screening and clinical testing for various genetic disorders, infectious diseases and cancers are also creating demand for high throughput nucleic acid preparation. Growing geriatric population and rising healthcare spending in developing nations also provides growth opportunities for market players in the forecast period.

PEST Analysis Political: Laws and regulations imposed by governments for research using DNA and RNA samples could impact the market. Changes in healthcare policies will also have effects. Economic: Factors like GDP growth, income levels, healthcare spending will drive demand. Rise in research activities and focus on precision medicine boost the market. Social: Growing awareness about personalized medicine and importance of genetic testing are important. Social trends also promote preventive healthcare and wellness. Technological: Advancements in fields like next generation sequencing, lab automation, bioinformatics are key for market growth. Miniaturization and portability of equipment expand applications. Developments in sample collection and storage methods improve efficiency. Geographical regions where the market in terms of value is concentrated include North America and Europe. North America accounts for the largest share in the global market due to presence of well-established healthcare industry and research institutes. Europe also captures notable share due to growing biotech sector and research funding. The Asia Pacific region is projected to be the fastest growing market during the forecast period. This is attributed to factors such as increasing healthcare expenditure, growing awareness, expanding biotech industry and rising government investments in research. Countries like China, India offer growth opportunities as they focus on healthcare infrastructure development.

Get more insights on DNA And RNA Sample Preparation Market

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Nucleic Acid Sample Preparation Market Future Trends to Look Out | Bis Research

Nucleic acid sample preparation refers to the set of processes and techniques employed to isolate, purify, and prepare nucleic acids (DNA or RNA) from various biological samples for downstream applications and analysis. 

The global Nucleic Acid Sample Preparation Market is projected to reach $5,615.9 million by 2033 from $2,922.8 million in 2023, growing at a CAGR of 6.75% during the forecast period 2023-2033.

 Nucleic Acid Sample Preparation Overview

This process is critical for ensuring the integrity and quality of nucleic acids, which are essential for reliable and accurate downstream applications such as polymerase chain reaction (PCR), sequencing, and gene expression analysis.

Key Steps in Nucleic Acid Sample Preparation

Sample Collection 

Cell Lysis 

Nucleic Acid Isolation 

Purification 

Quantification and Quality Assessment 

Grab a look at the free sample page for more understanding click here !

Nucleic Acid Sample Preparation Important Considerations 

Contamination - Avoiding contamination with nucleases, other nucleic acids, and environmental contaminants is critical. Use nuclease-free reagents and consumables. 

Sample Handling - Gentle handling minimizes mechanical shearing of nucleic acids. 

Control Samples - Always include control samples to monitor for contamination and process consistency.

Sample Collection and Preparation 

Biological Source  - Samples can be obtained from various sources such as blood, tissue, saliva, buccal swabs, or cultured cells.

Preservation - Immediate and appropriate preservation is crucial. For RNA, samples should be stabilized quickly using RNA stabilizing agents (e.g., RNAlater) to prevent degradation by RNases. For DNA, samples should be kept at low temperatures or preserved in ethanol.

Cell Lysis 

Lysis Buffers: The choice of lysis buffer depends on the sample type and the nucleic acid to be extracted.

Mechanical Disruption: Methods like bead beating, sonication, or homogenization are often used to physically disrupt tough tissue samples.

Nucleic Acid Extraction

Phenol-Chloroform Extraction: This traditional method uses phenol and chloroform to separate proteins from nucleic acids, followed by ethanol precipitation to concentrate the nucleic acids.

Silica Column-Based Extraction: Common in commercial kits, this method involves binding nucleic acids to a silica membrane in the presence of chaotropic salts, followed by washing and elution.

Magnetic Beads: Nucleic acids bind to magnetic beads under specific conditions, allowing for easy washing and elution with the help of a magnetic field.

4. Purification

RNase and DNase Treatment: To remove contaminating RNA from DNA preparations, DNase treatment is applied, and vice versa for RNA preparations.

Column Wash Steps: Additional wash steps in column-based methods help to remove impurities such as proteins, salts, and other contaminants.

5. Quantification and Quality Assessment

Spectrophotometry: Measuring absorbance at 260 nm (A260) provides a quantitative estimate of nucleic acid concentration. The A260/A280 ratio indicates protein contamination, with ideal values around 1.8 for DNA and 2.0 for RNA.

Fluorometry: More sensitive than spectrophotometry, fluorometric assays (e.g., Qubit) use fluorescent dyes that bind specifically to nucleic acids.

Electrophoresis: Agarose gel electrophoresis can be used to assess the integrity and size distribution of the nucleic acids.

6. Storage

Short-Term Storage: Nucleic acids can be stored at 4°C for short-term use.

Long-Term Storage: For long-term preservation, DNA is stored at -20°C or -80°C, while RNA is best stored at -80°C to prevent degradation.

Nucleic Acid Sample Preparation Market Drivers 

Increasing demand for molecular diagnostics 

Advancements in Biotechnology and Genomics 

Rising Research and Development Activities 

Expansion of Biopharmaceutical Manufacturing 

Key Market Players 

 Agilent Technologies, Inc.

 Autogen, Inc.

 Bio-Rad Laboratories, Inc.

Roche AG

Merck KGaA

and many others  

Visit our Precision Medicine Vertical Page Click Here !

Market Segmentation

Product Type 

End Users 

Applications 

Geography 

Various different applications involved are as follows 

Clinical Diagnostics 

Biomedical Research 

Pharmaceutical and Biotechnology Development

Agricultural Biotechnology 

And many others 

Recent Developments in the Nucleic Acid Sample Preparation  Market Market

Qiagen N.V. introduced two groundbreaking additions to its sample technologies portfolio, i.e., the TissueLyser III that facilitates high-throughput disruption of diverse biological samples and the RNeasy PowerMax Soil Pro Kit that isolates high-purity RNA from challenging soil samples using advanced Inhibitor Removal Technology.

PerkinElmer introduced the CHEF Magnetic Bead Cleanup System, providing automated nucleic acid purification through advanced magnetic bead technology. This novel system would help automate the nucleic acid purification process efficiently.

Conclusion

In conclusion, the Nucleic Acid Sample Preparation  market continues to experience significant growth and expansion driven by a multitude of factors. The increasing demand for molecular diagnostics, fueled by the prevalence of infectious diseases and genetic disorders, underscores the importance of nucleic acid-based testing in clinical settings. 

Overall, the Nucleic Acid Sample Preparation  market is poised for continued expansion, driven by ongoing advancements in technology, increasing research and development activities, and the growing demand for molecular diagnostics and personalized medicine. 

[blueweave]

Global Nucleic Acid Isolation and Purification Market size at USD 4.22 billion in 2023. During the forecast period between 2024 and 2030, BlueWeave expects the Global Nucleic Acid Isolation and Purification Market size to expand at a CAGR of 9.23% reaching a value of USD 8.47 billion by 2030. Growing R&D efforts and an increase in the use of sequencing platforms for clinical diagnostics are two key growth drivers for the Global Nucleic Acid Isolation and Purification Market. The is also expected to be driven by an increase in genomics research as well as new product launches.

Opportunity: Rising application for diagnostics

The Global Nucleic Acid Isolation and Purification Market is segmented into drug discovery & development, precision medicine, diagnostics, agriculture and animal research, and other, based on application. The diagnostics segment holds the largest share in the Global Nucleic Acid Isolation and Purification Market. According to research published on ScienceDirect, RNA/DNA genetic tests are the most reliable for identifying infectious illnesses and determining a person's vulnerability to certain diseases, including COVID-19. Drug discovery and development is anticipated to register the highest growth rate during the forecast period.

Impact of Escalating Geopolitical Tensions on Global Nucleic Acid Isolation and Purification Market

The escalating geopolitical tensions restrict the growth of the Global Nucleic Acid Isolation and Purification Market. For instance, Ukraine has been emerging as the leading destination for clinical research and trials of various diseases, particularly cancer. The presence of an organized and digitized health system makes it cheaper to accommodate medical research in Ukraine compared to many other Western European nations. However, Russia’s invasion of Ukraine disrupted the medical research ecosystem in the country. Many reports reveal that Ukraine has a large number of clinical research specialists as well as infrastructure, which directly impacts the demand for nucleic acid isolation and purification, hindering its global market growth.

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[amey-inkwood]

Chromatography Resin Market: Top 5 Industry Applications

According to Inkwood Research, the global chromatography resin market is anticipated to progress with a CAGR of 7.64% during the forecast period of 2024 to 2032. Chromatography resins are emerging as indispensable tools in analytical chemistry and biotechnology, predominantly owing to their remarkable selectivity and versatility. 

The significant rise in research and development (R&D), specifically within the pharmaceutical & biopharmaceutical industries serves as a primary catalyst for the global chromatography resin market’s growth. 

These resins, essential for the refinement as well as the isolation of biotherapeutics, are increasingly essential across applications. These include drug discovery, biopharmaceutical production, and the enhancement of chromatography technologies, among others.

Accordingly, in this blog, we will explore the top five applications of chromatography resins, highlighting their significance across various industries.

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The biopharmaceutical industry relies heavily on chromatography resins for the purification of therapeutic proteins and antibodies. These resins, particularly ion exchange and affinity resins, are designed to selectively bind and separate target proteins from complex biological mixtures, such as cell culture supernatants or fermentation broths. 

Accordingly, let’s take a closer look at major companies engaged in the process of protein purification in the biopharma sector – 

F. Hoffmann-La Roche is a top patent filer in protein affinity chromatography and is active in diagnostic test development, biotechnology, and drug discovery. It employs protein affinity chromatography in its R&D, particularly for purifying and characterizing proteins used in diagnostics and therapeutics. 

E. Merck and Sanofi are also notable patent filers in this field.

In the last four years alone, there have been more than 787,000 patents filed and granted in the pharmaceutical industry, according to a 2023 report on Innovation in Pharma: Protein Affinity Chromatography.

By exploiting the unique physicochemical properties of the target molecules, chromatography resins enable the highly efficient purification of biopharmaceuticals, ensuring product safety, purity, and potency.

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2. Food and Beverage Analysis:

The food and beverage industry relies on chromatography resins for the analysis and quality control of various products. Ion-exchange and size-exclusion resins are utilized for the separation and quantification of sugars, organic acids, and other food components, ensuring product quality and adherence to regulatory standards. Furthermore, affinity resins are employed for the selective removal of undesirable compounds, such as mycotoxins or allergens, from food and beverage products.

Market Position: According to Inkwood Research, food & beverage is set to be a key end use in the chromatography resin market, during the forecast years, 2024 to 2032.

With a growing demand for natural and clean-label products, chromatography resins are invaluable in isolating and purifying bioactive compounds, thereby facilitating the production of top-tier, compliant food and beverage offerings.

3. Biomolecule Separations in Academic and Research Settings –

Chromatography resins are indispensable tools in academic and research laboratories, enabling the separation and purification of a wide range of biomolecules, including proteins, nucleic acids, and carbohydrates. 

These resins are employed in various applications, such as protein structure determination, enzyme purification, and the isolation of biologically active compounds from natural sources. The versatility and selectivity of chromatography resins have facilitated numerous scientific discoveries and advancements in fields like biochemistry, molecular biology, and biotechnology.

Accordingly, Bio-Rad Laboratories Inc introduced EconoFit Low-Pressure Prepacked Chromatography Column Packs in June 2022. These packs are designed to facilitate resin screening experiments during the creation of protein purification workflows.

Stay up-to-date with what’s trending in the Global Chromatography Resin Market

4. Environmental Analysis and Remediation – 

Various World Health Organization (WHO) studies have revealed that over 10% of women face infertility risks due to exposure to prevalent environmental contaminants –  Lead, cadmium, mercury, and other heavy metals are known to cause reproductive disorders. 

Besides, numerous contaminants, such as heavy metals as well as polycyclic aromatic hydrocarbons (PAHs), have been linked to hormone imbalances.

Chromatography resins, in this regard, have emerged as valuable tools in environmental analysis and remediation processes. Ion-exchange resins, for instance, are employed for the selective removal of heavy metals and other contaminants from wastewater and industrial effluents. 

Additionally, specialized resins are utilized for the extraction and concentration of trace organic pollutants from environmental samples, facilitating their subsequent analysis and quantification.

5. Small Molecule Purification in Pharmaceutical Industry – 

Beyond biomolecules, chromatography resins play a crucial role in the purification of small organic molecules, including active pharmaceutical ingredients (APIs) and drug intermediates. Reverse-phase resins, utilizing hydrophobic interactions, are widely employed for the separation and purification of these compounds. This application is particularly important in the pharmaceutical industry, where high purity and consistent quality of drugs are paramount for ensuring patient safety and efficacy.

As the demand for high-purity products and the need for advanced analytical techniques continue to grow, chromatography resins are projected to remain at the forefront of scientific and industrial endeavors. Ongoing research and development efforts are focused on designing novel resins with enhanced selectivity, improved capacity, and greater chemical and physical stability, further expanding the growth potential of the chromatography resin market during the forecast years.

FAQ

What are the main types of chromatography resins?

Common types of chromatography resins include agarose for gel filtration, ion exchange resins, affinity resins, and hydrophobic interaction resins.

How are chromatography resins chosen?

The selection of chromatography resins depends on factors like the target molecule, sample characteristics, desired purity, and the specific interactions needed for separation.

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DNA Extraction Kits Market is Estimated to Witness High Growth Owing to Increasing Demand for Nucleic Acid-Based Molecular Tests

DNA extraction kits are essential tools used to isolate and purify DNA from a variety of biological samples in life science research and clinical diagnostics. DNA extraction kits can purify DNA from peripheral blood, tissue, cells, plasma, serum, saliva, stool, and other biological samples. Purified DNA is then utilized in various downstream applications including PCR, DNA sequencing, molecular testing, and synthetic biology. Common uses of DNA extraction kits in clinical applications include cancer diagnostics, forensic testing, prenatal testing, infectious disease testing, genetic testing, and personalized medicine. The global DNA extraction kits market is estimated to be valued at US$1.2 Bn in 2023 and is expected to exhibit a CAGR of 5.9% over the forecast period 2023-2031, as highlighted in a new report published by Coherent Market Insights. Market Dynamics Increasing demand for nucleic acid-based molecular diagnostic tests is expected to drive growth of the DNA extraction kits market size over the forecast period. Molecular diagnostic testing is gaining immense popularity over traditional diagnostics due to its accuracy, high sensitivity, and specificity. Growing prevalence of cancer and infectious diseases is propelling demand for rapid and accurate molecular testing which require purified DNA obtained from extraction kits. According to WHO, cancer burden is expected to grow to 27.5 million new cancer cases and 16.3 million cancer deaths by 2040. Technological advancements in extraction methods allowing purification of DNA even from complex biological samples is another factor fueling the DNA extraction kits market growth. Automated liquid handling workstations integrated with magnetic bead-based DNA extraction techniques have simplified workflow and increased throughput of purification process. SWOT Analysis Strength: DNA extraction kits provide an easy and efficient way to isolate and purify DNA from various biological samples like blood, saliva, and tissues. These kits use optimized procedures and reagents to reliably extract high yields of pure DNA. They minimize hands-on time and produce consistent results. Some kits are automated and high-throughput, allowing labs to extract DNA from large numbers of samples simultaneously in an easy and standardized manner. Weakness: DNA extraction kits rely on consumables like columns, plates and reagents that need regular replenishment, increasing long-term costs. Additionally, automation requires larger initial investments. The quality of extracted DNA can vary between kits depending on their purification chemistry and protocols. Opportunity: Growth in genomic researchareas like precision medicine, cancer research and genetic testing is driving increased demand for DNA extraction. Rising focus on pharmacogenomics and companion diagnostics also presents commercialization opportunities. Point-of-care extraction devices and portable battery-operated systems allow decentralized testing and expand the addressable market. Threats: Competition from in-house extraction methods developed by research institutes poses a challenge. Stringent regulatory approvals for diagnostic-grade kits increase barriers. Intellectual property disputes between manufacturers also affect commercialization strategies. Key Takeaways The global DNA extraction kits market is expected to witness high growth over the forecast period driven by increasing genomics funding and expanding application areas.

The market is dominated by North America currently due to extensive R&D spending and presence of leading life science companies. Asia Pacific is poised to be the fastest growing regional market due to growing genomics research in countries like China and India as well as increasing healthcare investments. Key players operating in the DNA extraction kits market are Qiagen N.V., Thermo Fisher Scientific, Hoffmann-La Roche AG, Merck KGaA, Agilent Technologies, Bio-Rad Laboratories Inc., Illumina, Inc., Promega Corporation, LGC Ltd., and Takara Bio, Inc. Companies are focused on portfolio expansion through new product launches. For example, in 2021 Thermo Fisher launched the MagMAX Cellular RNA Isolation Kit designed for high-throughput extraction of total RNA from cultured cells.

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[rohit0024]

Nucleic Acid Isolation And Purification Market Worth $9.8 Billion By 2028

Nucleic Acid Isolation And Purification Market Growth & Trends The global nucleic acid isolation and purification market size is anticipated to reach USD 9.8 billion by 2028, based on a new report by Grand View Research, Inc. The market is expected to expand at a CAGR of 11.4% from 2021 to 2028. The growth can be primarily attributed to the technological advancements in molecular detection…

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Nucleic Acid Isolation And Purification Market Worth $9.8 Billion By 2028

The global nucleic acid isolation and purification market size is anticipated to reach USD 9.8 billion by 2028, based on a new report by Grand View Research, Inc. The market is expected to expand at a CAGR of 11.4% from 2021 to 2028. The growth can be primarily attributed to the technological advancements in molecular detection platforms. The technologies such as robotic liquid handling in…

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Global Nucleic Acid Isolation and Purification Market Size and Growth Forecast to 2030 | VynZ Research

The Global Nucleic Acid Isolation and Purification Market size will reach USD 7.9 Billion by 2030 and is expected to develop at a CAGR of 9.2% during the forecast period (2022-2030), according to VynZ Research. For the forecast year 2022-2030, as well as the historical period 2018-2021, the Global Nucleic Acid Isolation and Purification Market has been studied.

The research report provides a comprehensive and insightful examination of the Global Nucleic Acid Isolation and Purification Market and includes market analysis on segmentation, dynamics, competition, and regional development. It considers the Global Nucleic Acid Isolation and Purification Market's CAGR, value, volume, revenue, production, consumption, sales, manufacturing cost, pricing, and other significant parameters. The forecasts in the report are based on well-established research methodology and assumptions.

Explore the recent findings of the Global Nucleic Acid Isolation and Purification Market by purchasing a single user PDF@ https://www.vynzresearch.com/healthcare/nucleic-acid-isolation-and-purification-market/request-sample

Individual strategies were examined in the Global Nucleic Acid Isolation and Purification Market study, followed by business profiles of Global Nucleic Acid Isolation and Purification Market providers. The study includes an 'Industry Landscape' section that provides readers with a comprehensive view and firms’ market share analysis of major industry players in the Global Nucleic Acid Isolation and Purification Market.

Most of the major players in the Global Medication Management Market are profiled in the report. The strengths and weaknesses, business developments, recent innovations, mergers and acquisitions, expansion plans, global footprint, market presence, and product portfolios of key market competitors are all covered in the company profiling section.

The following are some of the major and developing players in the Global Nucleic Acid Isolation and Purification Market:

·         Thermo Fisher Scientific

·         F. Hoffman-La Roche

·         Danaher Corporation

·         Qiagen N.V.

·         Illumina

·         Agilent Technologies

·         Merck KGaA

·         Promega Corporation

·         Bio-Rad Laboratories

·         GE Healthcare

Breakdown of The Segments:

The Global Nucleic Acid Isolation and Purification Market is segmented by Product, Type, Application, End-User, and Geography in this study. This segmentation aids executives in planning their products and budgets depending on each segment's expected growth rates.

Product Insight and Forecast 2018-2030

·         Kits

·         Instruments

·         Reagents

Method Insight and Forecast 2018-2030

·         Column-Based

·         Magnetic Bead-Based

·         Reagent-Based

·         Others

Type Insight and Forecast 2018-2030

·         Messenger RNA

·         Plasmid DNA

·         Circulating Nucleic Acid

·         Total RNA

·         Microrna

·         PCR Cleanup

·         Genomic DNA

·         Others

Application Insight and Forecast 2018-2030

·         Precision Medicine

·         Diagnostics

·         Agriculture and Animal Research

·         Drug Discovery & Development

·         Others

End User Insight and Forecast 2018-2030

·         Contract Research Organizations

·         Academic and Government Research Institutes

·         Hospitals and Diagnostic Centers

·         Pharmaceutical and Biotechnology Companies

·         Other

Geographical Viewpoint:

The research overview provides the major industry trend and the global market's predicted volume based on the regional analysis. The elements that have driven and hampered the market's expansion are also mentioned in this market research analysis. The study is also equipped with the most advanced and effective techniques for gathering, recording, estimating, and evaluating market data.

FAQ

1.      Who are the most dominant players in the global market, and what elements are assisting them in gaining a competitive advantage?

2.      What are the strategies adopted by the key industry players to gain traction in the industry?

3.      By the end of the forecast period, what will the market size and growth rate?

4.      What are the biggest Global Nucleic Acid Isolation and Purification Market trends that are influencing market growth?

5.      In the global market, which segment had the biggest revenue share?

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About VynZ Research

VynZ Research is a global market research firm offering research, analytics, and consulting services on business strategies. VynZ have a recognized trajectory record and our research database is used by many renowned companies and institutions in the world to strategize and revolutionize business opportunities. The company focuses on providing valuable insights on various technology verticals such as Chemicals, Automotive, Transportation, Energy, Consumer Durables, Healthcare, ICT and other emerging technologies.

[123567-9qaaq9]

Nucleic Acid Sample Preparation Market Future Trends to Look Out | Bis Research

Nucleic Acid Sample Preparation  is a process used to extract and refine DNA or RNA molecules from biological samples, such as cells, tissues, or bodily fluids. This procedure is essential for various downstream applications in molecular biology, genetics, and biotechnology.

The global Nucleic Acid Sample Preparation Market is projected to reach $5,615.9 million by 2033 from $2,922.8 million in 2023, growing at a CAGR of 6.75% during the forecast period 2023-2033.

 Nucleic Acid Sample Preparation Overview

Nucleic acid sample preparation is the process of isolating and purifying DNA or RNA from various biological materials.This process ensures that the nucleic acids are free from contaminants and suitable for subsequent analysis of experiments. It involves a series of steps including sample collection and preservation, cell lysis, nucleic acid extraction, purification, quantification, quality assessment, and storage. 

Grab a look at the free sample page for more understanding click here !

Nucleic Acid Sample Preparation Important Considerations 

Contamination - Avoiding contamination with nucleases, other nucleic acids, and environmental contaminants is critical. Use nuclease-free reagents and consumables. 

Sample Handling - Gentle handling minimizes mechanical shearing of nucleic acids. 

Control Samples - Always include control samples to monitor for contamination and process consistency.

Sample Collection and Preparation 

Biological Source  - Samples can be obtained from various sources such as blood, tissue, saliva, buccal swabs, or cultured cells.

Preservation - Immediate and appropriate preservation is crucial. For RNA, samples should be stabilized quickly using RNA stabilizing agents (e.g., RNAlater) to prevent degradation by RNases. For DNA, samples should be kept at low temperatures or preserved in ethanol.

Cell Lysis 

Lysis Buffers: The choice of lysis buffer depends on the sample type and the nucleic acid to be extracted.

Mechanical Disruption: Methods like bead beating, sonication, or homogenization are often used to physically disrupt tough tissue samples.

Nucleic Acid Extraction

Phenol-Chloroform Extraction: This traditional method uses phenol and chloroform to separate proteins from nucleic acids, followed by ethanol precipitation to concentrate the nucleic acids.

Silica Column-Based Extraction: Common in commercial kits, this method involves binding nucleic acids to a silica membrane in the presence of chaotropic salts, followed by washing and elution.

Magnetic Beads: Nucleic acids bind to magnetic beads under specific conditions, allowing for easy washing and elution with the help of a magnetic field.

4. Purification

RNase and DNase Treatment: To remove contaminating RNA from DNA preparations, DNase treatment is applied, and vice versa for RNA preparations.

Column Wash Steps: Additional wash steps in column-based methods help to remove impurities such as proteins, salts, and other contaminants.

5. Quantification and Quality Assessment

Spectrophotometry: Measuring absorbance at 260 nm (A260) provides a quantitative estimate of nucleic acid concentration. The A260/A280 ratio indicates protein contamination, with ideal values around 1.8 for DNA and 2.0 for RNA.

Fluorometry: More sensitive than spectrophotometry, fluorometric assays (e.g., Qubit) use fluorescent dyes that bind specifically to nucleic acids.

Electrophoresis: Agarose gel electrophoresis can be used to assess the integrity and size distribution of the nucleic acids.

6. Storage

Short-Term Storage: Nucleic acids can be stored at 4°C for short-term use.

Long-Term Storage: For long-term preservation, DNA is stored at -20°C or -80°C, while RNA is best stored at -80°C to prevent degradation.

Nucleic Acid Sample Preparation Market Drivers 

Increasing demand for molecular diagnostics 

Advancements in Biotechnology and Genomics 

Rising Research and Development Activities 

Expansion of Biopharmaceutical Manufacturing 

Key Market Players 

 Agilent Technologies, Inc.

 Autogen, Inc.

 Bio-Rad Laboratories, Inc.

Roche AG

Merck KGaA

and many others  

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Market Segmentation

Product Type 

End Users 

Applications 

Geography 

Various different applications involved are as follows 

Clinical Diagnostics 

Biomedical Research 

Pharmaceutical and Biotechnology Development

Agricultural Biotechnology 

And many others 

Recent Developments in the Nucleic Acid Sample Preparation  Market Market

Qiagen N.V. introduced two groundbreaking additions to its sample technologies portfolio, i.e., the TissueLyser III that facilitates high-throughput disruption of diverse biological samples and the RNeasy PowerMax Soil Pro Kit that isolates high-purity RNA from challenging soil samples using advanced Inhibitor Removal Technology.

PerkinElmer introduced the CHEF Magnetic Bead Cleanup System, providing automated nucleic acid purification through advanced magnetic bead technology. This novel system would help automate the nucleic acid purification process efficiently.

Conclusion

In conclusion, the Nucleic Acid Sample Preparation  market continues to experience significant growth and expansion driven by a multitude of factors. The increasing demand for molecular diagnostics, fueled by the prevalence of infectious diseases and genetic disorders, underscores the importance of nucleic acid-based testing in clinical settings. 

Overall, the Nucleic Acid Sample Preparation  market is poised for continued expansion, driven by ongoing advancements in technology, increasing research and development activities, and the growing demand for molecular diagnostics and personalized medicine. 

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Nucleic Acid Isolation And Purification Market Poised To Surge $9.8 Billion By 2028

The global nucleic acid isolation and purification market size is anticipated to reach USD 9.8 billion by 2028, based on a new report by Grand View Research, Inc. The market is expected to expand at a CAGR of 11.4% from 2021 to 2028. The growth can be primarily attributed to the technological advancements in molecular detection platforms. The technologies such as robotic liquid handling in automated DNA extraction systems, have improved the process flow. Such automation has streamlined all the tasks involved in various processes, such as DNA extraction from samples, serial dilution, and picking the desired gene of interest.

The outbreak of SARS-CoV-2 in late 2019 in China quickly translated into a global pandemic, which led to high demand for efficient and affordable diagnostic tests that could be carried out in non-clinical as well as clinical settings. This also led to high demand for nucleic acid extraction kits which in turn has led the key players to increase their manufacturing capabilities. For instance, in March 2020, QIAGEN announced the expansion of its production capacity in the U.S. and Europe to reach 20 million monthly patient tests by the end of 2020.

Moreover, rapid diagnosis, effective treatment options, and future prevention plans are essential in the management of COVID-19. The current race for the development of cost-effective, point-of-contact test kits and efficient laboratory methodologies for the detection of coronavirus infection has driven a new frontier of diagnostic innovation. The increase in adoption of PCR for SARS-CoV-2 detection by a wide range of commercial laboratories drives the market, as nucleic acid isolation and purification is an important step in the PCR workflow.

Request a free sample copy or view report summary: Nucleic Acid Isolation And Purification Market Report

Nucleic Acid Isolation And Purification Market Report Highlights

The kits and reagents segment accounted for the largest revenue share in 2020 owing to the rising number of research studies focused on understanding rare and common genome-based diseases

The RNA isolation and purification segment holds the largest revenue share in 2020 due to its increasing use for the analysis of COVID samples

The DNA isolation and purification segment is expected to witness the fastest growth rate owing to its use in a variety of molecular biology applications

The magnetic beads segment accounted for the largest revenue share in 2020 and is expected to continue the trend owing to the advantage of obtaining the purest possible form of DNA/RNA and excluding other unwanted materials from the sample mixture

The diagnostics segment dominated the market and accounted for the largest revenue share in 2020 owing to the high adoption of NAI and P products for detecting and characterizing microorganisms

The pharmaceutical and biotechnology companies are expected to witness the fastest growth owing to their increasing research and development activities for drug development

North America has emerged as the highest revenue-generating region due to intensive research projects in the region for cancer detection and other chronic disorders

Companies operating in the market are launching new and automated systems for nucleic acid isolation and purification. For instance, in March 2021, QIAGEN N.V. launched an automated sample processing system the QIAcube Connect MDx for molecular diagnostic laboratories

The system helps in the automation of several steps such as lysis, binding, washing, and elution for RNA, DNA, and protein sample processing

Nucleic Acid Isolation And Purification Market Segmentation

Grand View Research has segmented the global nucleic acid isolation and purification market on the basis of product, type, method, application, end-use, and region:

Nucleic Acid Isolation & Purification Product Outlook (Revenue, USD Million, 2017 - 2028)

Kits & Reagents

Instruments

Nucleic Acid Isolation & Purification Type Outlook (Revenue, USD Million, 2017 - 2028)

DNA Isolation & Purification (I&P)

RNA Isolation & Purification

Genomic DNA I&P

Plasmid DNA I&P

Viral DNA I&P

Other

miRNA Isolation & Purification

mRNA Isolation & Purification

Total RNA Isolation & Purification

Other

Nucleic Acid Isolation & Purification Method Outlook (Revenue, USD Million, 2017 - 2028)

Column-based

Magnetic Beads

Reagent-based

Others

Nucleic Acid Isolation & Purification Application Outlook (Revenue, USD Million, 2017 - 2028)

Precision Medicine

Diagnostics

Drug Discovery & Development

Agriculture and Animal Research

Other Applications

Nucleic Acid Isolation & Purification End-use Outlook (Revenue, USD Million, 2017 - 2028)

Academic Research Institutes

Pharmaceutical & Biotechnology Companies

Contract Research Organizations

Hospitals and Diagnostic Centers

Other End-use

Nucleic Acid Isolation & Purification Regional Outlook (Revenue, USD Million, 2017 - 2028)

North America

Europe

Asia Pacific

Latin America

Middle East and Africa (MEA)

U.S.

Canada

Germany

U.K.

China

Japan

Brazil

Mexico

South Africa

List of Key Players of Nucleic Acid Isolation And Purification Market

QIAGEN

Thermo Fisher Scientific, Inc.

Illumina, Inc.

Danaher

F. Hoffmann-La Roche AG

Merck KGaA

Agilent Technologies

Bio-Rad Laboratories, Inc.

Takara Bio, Inc.

Promega Corporation

New England Biolabs

LGC Limited

Abcam plc

Norgen Biotek Corp

AutoGen, Inc.

Biogenuix

PCR Biosystems, Inc.

MagGenome

Apical Scientific Sdn. Bhd

MACHEREY-NAGEL GmbH & Co. KG

About Grand View Research

Grand View Research, Inc. is a U.S. based market research and consulting company, registered in the State of California and headquartered in San Francisco. The company provides syndicated research reports, customized research reports, and consulting services. To help clients make informed business decisions, we offer market intelligence studies ensuring relevant and fact-based research across a range of industries, from technology to chemicals, materials and healthcare.

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Nucleic Acid Isolation And Purification Market Expanding At A CAGR 11.4% For The Forecast Period From 2021 To 2028: Grand View Research Inc.

Nucleic Acid Isolation And Purification Market Expanding At A CAGR 11.4% For The Forecast Period From 2021 To 2028: Grand View Research Inc.

San Francisco, 9 Dec 2021: The Report Nucleic Acid Isolation And Purification Market Size, Share & Trends Analysis Report By Product (Instruments, Kits & Reagents), By Type, By Application, By Method (Column-based, Magnetic Beads), By End-use, By Region, And Segment Forecasts, 2021 – 2028 The global nucleic acid isolation and purification market size is anticipated to reach USD 9.8 billion by…