#adjustable micropipettes

[liquidhandlingproduct]

Adjustable vs. Fixed Volume Micropipettes - Which is Right for Your Lab?

In the precision-centric world of laboratory science, the choice of pipetting tools is crucial to the efficiency and accuracy of experiments. Among the essential tools in any lab are micropipettes, specifically adjustable and fixed volume micropipettes. Each type has its unique advantages, and choosing between them depends on your lab's specific needs. Let's delve into the characteristics of variable volume micropipettes, Microlit micropipettes (a renowned brand known for its precision tools), fixed volume micropipettes, and adjustable micropipettes to help you make an informed decision.

Variable Volume Micropipettes

Variable volume micropipettes are versatile tools that allow researchers to adjust the volume of liquid dispensed, making them suitable for a wide range of applications. This adjustability is particularly beneficial in experimental setups that require different volumes or in labs with varied pipetting needs. Variable volume micropipettes ensure that you can perform multiple tasks with the same pipette, reducing the need for multiple fixed volume pipettes and saving space and resources.

Microlit Micropipette

Microlit is a brand known for its high-quality, ergonomic pipettes designed to provide accurate and precise liquid measurement with reduced user fatigue. They offer both adjustable and fixed volume micropipettes, catering to the diverse needs of laboratories. Microlit micropipettes are engineered with user comfort in mind, featuring lightweight designs and easy volume adjustments. Their products are an excellent choice for labs looking for reliable, ergonomic pipetting solutions.

Fixed Volume Micropipettes

Fixed volume micropipettes are designed to dispense a specific volume of liquid. These pipettes offer simplicity and speed, as they eliminate the need to adjust the volume for each use, making them ideal for repetitive tasks requiring the same volume. Fixed volume micropipettes are known for their reliability and consistency, providing precise measurements every time. They are particularly useful in high-throughput settings where the same procedure is repeated multiple times.

Adjustable Micropipettes

Adjustable micropipettes combine the versatility of variable volume pipettes with the precision and ease of use characteristic of fixed volume models. They allow for quick adjustments of the dispensed volume, catering to a broad range of tasks within a single experiment. Adjustable micropipettes are perfect for labs that handle complex protocols requiring different volumes but still demand the precision and accuracy that fixed volume pipettes offer.

Which is Right for Your Lab?

Choosing between adjustable and fixed volume micropipettes depends on your lab's specific needs:

For Versatility and Broad Application Range: If your lab performs a wide variety of experiments that require different volumes, variable volume or adjustable micropipettes are the way to go. They offer the flexibility needed to accommodate diverse protocols.

For Repetitive Tasks and High Throughput: If you're working in an environment where speed and consistency are paramount, and the tasks involve repetitive pipetting of the same volume, fixed volume micropipettes offer the efficiency and reliability you need.

For Precision and Comfort: Brands like Microlit offer both adjustable and fixed volume micropipettes designed with ergonomic features to reduce fatigue and improve accuracy, making them a good choice regardless of the type you choose.

In conclusion, the decision between adjustable and fixed volume micropipettes should be guided by the specific requirements of your laboratory. Consider the nature of your experiments, the importance of versatility versus speed, and the ergonomic needs of your team. By carefully assessing these factors, you can select the pipetting tools that will best support your research and ensure the success of your lab's operations.

[labotronicsscientific]

Adjustable Volume Micro Pipette

Adjustable Volume Micro Pipette LB-10AVP is a single-channel micropipette with a pipetting range of 0.1 to 2.5 µL. It is autoclavable at 121℃ under 1 bar pressure for 20 minutes. Features a push-button for volume adjustment and offers comfortable finger support. Equipped with a low-force tip ejector for easy pipetting. The tip cones are constructed with chemical-resistant material for extended service life.

[sscientifique]

SScientifique: India's Leading Micropipette Manufacturer Empowering Precision in Every Drop

In the intricate world of scientific research and diagnostics, accuracy isn’t optional—it’s essential. At the heart of most lab processes lies the need for consistent and ultra-precise liquid measurement. This is where micropipettes play an irreplaceable role. As a cornerstone tool in laboratories worldwide, micropipettes enable researchers to handle fluids with micro-level precision.

Among India’s most trusted names in this space is SScientifique, a leading manufacturer of micropipettes and scientific instruments based in Uttar Pradesh, India. For over a decade, SScientifique has dedicated itself to developing world-class lab tools that combine innovation, affordability, and uncompromising quality.

This article explores why SScientifique stands out as the preferred choice for Indian and global laboratories alike, especially when it comes to micropipettes.

Understanding the Importance of Micropipettes in Laboratories

Micropipettes are precision instruments used to aspirate and dispense accurate volumes of liquid, usually in the microliter (µL) range. They are widely utilized across:

Molecular biology

Biochemistry

Clinical diagnostics

Pharmaceutical research

Academic and teaching labs

Environmental science labs

A variation of even 1 µL in measurement can lead to significant discrepancies in experimental outcomes. Hence, researchers rely heavily on micropipettes that offer reproducibility, ergonomic design, and easy calibration.

SScientifique: A Pioneer in Indian Micropipette Manufacturing

With headquarters and manufacturing units located in Uttar Pradesh, SScientifique has positioned itself as a leading force in laboratory instrument production, particularly in the realm of micropipettes. Here's why they are a top choice:

1. Indigenous Design & Engineering

Unlike many Indian suppliers who import and rebrand products, SScientifique develops and manufactures its micropipettes domestically. This allows for complete control over product quality, innovation, and cost.

2. Wide Range of Products

SScientifique offers an extensive selection of single-channel and multi-channel micropipettes, catering to varying needs:

Fixed volume micropipettes for repetitive tasks

Adjustable volume micropipettes for versatile applications

Low-retention tips and accessories

Each pipette is tested rigorously to comply with ISO 8655 standards for accuracy and precision.

3. Ergonomic and User-Friendly Design

Designed with laboratory professionals in mind, SScientifique micropipettes feature:

Lightweight construction

Comfortable grip

Smooth plunger mechanism

Convenient volume setting with clear digital display

This ergonomic build reduces hand fatigue during prolonged pipetting sessions.

4. Affordable Without Compromise

SScientifique provides laboratory tools that rival international brands in performance—yet are priced to suit Indian budgets. The brand's commitment to affordability empowers even small-scale laboratories to access high-precision tools.

5. Customer-Centric Service

Beyond manufacturing, SScientifique is recognized for its stellar support services:

Calibration and maintenance

Spare parts availability

Technical support and training

Their responsive team ensures clients receive fast, reliable assistance post-purchase.

Why Choose SScientifique Micropipettes?

Here are the key benefits that make SScientifique micropipettes the instrument of choice for laboratories:

✅ High Accuracy: Every unit is factory calibrated and tested to ensure minimal error and maximum repeatability.

✅ Ease of Operation: Easy volume setting, tip ejection, and lightweight handling improve efficiency.

✅ Universal Compatibility: Compatible with standard pipette tips available in the Indian and global markets.

✅ Durable Construction: Built with high-grade plastics and corrosion-resistant internal parts.

✅ Customization Options: Available in bulk with private branding and special configurations for institutional buyers.

What Customers Say

"We transitioned to SScientifique micropipettes last year, and the improvement in handling and accuracy was immediate. Highly recommended for research use." — Dr. Shalini Prasad, Biotech Researcher, Delhi

"Affordable and sturdy, SScientifique's pipettes are ideal for educational institutions like ours. We no longer depend on overpriced imports." — Prof. Ramesh Yadav, Department of Chemistry, Lucknow

Other Lab Instruments by SScientifique

SScientifique is more than just a micropipette manufacturer. Their extensive catalog includes:

Centrifuges (manual and digital)

Incubators and Hot Air Ovens

Compound and Digital Microscopes

Lab Glassware and Plasticware

Surgical Instruments

Digital Balances

This makes SScientifique a one-stop destination for laboratory procurement needs across education, research, healthcare, and diagnostics.

Bulk Orders & Distribution

SScientifique welcomes institutional buyers, resellers, and government tenders. The company provides:

Special pricing for large orders

Institutional branding on products

Timely delivery across India

PAN India dealership support

Future Innovations: What’s Next?

With the growing demand for automated and digital lab tools, SScientifique is actively investing in R&D to introduce:

Electronic micropipettes with digital calibration

Multi-channel pipettes for 96-well plate handling

Eco-friendly lab consumables

The brand envisions becoming India’s most innovative and trusted lab instrument supplier by 2030.

How to Order

Ordering SScientifique micropipettes is quick and hassle-free:

☎⃣ Call: +91-73747707507 📧 Email: sales.sscientifique@gmail.com 🌐 Website: www.sscientifique.com

Customer inquiries are usually answered within 24 hours. Shipping is available across India and select global markets.

Final Thoughts

In the competitive world of scientific instruments, SScientifique stands out by combining reliability, affordability, and innovation. Their micropipettes are built to serve the precise demands of Indian researchers, educators, and scientists.

Whether you're equipping a high-tech biotech lab or a college practical classroom, choosing the right pipette is crucial—and with SScientifique, you're choosing excellence made in India.

Empower your research with precision you can trust. Choose SScientifique Micropipettes today.

[accumax]

Micropipette Accuracy vs. Precision: What’s the Difference? | Accumax

It is essential to achieve dependable and reproducible outcomes while working in a laboratory. The two main focal points that concern the performance of micropipettes are accuracy and precision. Even though these terms are used as synonyms quite often, there is a difference particularly with respect to liquid handling devices such as micropipettes.  

We develop and manufacture micropipettes with the best accuracy and precision. In this blog we will discuss how Accumax micropipettes achieve accuracy and precision in the laboratory.  

Accuracy vs. Precision: The Discrepancies

Accuracy: Accuracy describes how close a measured value is to a benchmark. E.g,. For Pipettes, this means delivering the exact volume of liquid specified. A precise pipette will dispense 100 µL if set to dispense 100 µL. An accurate pipette will dispense 100 µL (or very close to it) while adjusted to 100 µL

Precision: Precision is better described as the repeated consistency of measurements. A precise pipette will dispense a certain quantity repetitively. That certain amount of liquid may not be the target amount, but a precise micropipette will always dispense that amount consistently.

Example Scenario

High Accuracy, Low Precision: The pipette delivers volumes close to the target (e.g., 99 µL, 101 µL, 100 µL) but with variation.  

High Precision, Low Accuracy: The pipette consistently delivers the same volume (e.g., 95 µL every time) but is far from the target.  

High Accuracy & High Precision: The pipette consistently delivers the exact target volume (e.g., 100 µL every time).  

You need both Accuracy and Precision to arrive at reliable lab results. 

How Accumax Ensures Accuracy and Precision at the Same Time

Our Micropipettes are built to provide optimal performance. This is how we achieve optimums:  

Superior Calibration & Quality Control: We calibrate our Micropipettes through rigorous processes to ensure that they comply with international requirements (ISO 8655) and they are tested for accuracy and precision before they leave the factory. 

Ergonomic & Consistent Design Accumax Micropipettes offer:   

One of the lowest plunge force action to improve liquid handling

The magnet-assisted piston mechanism ensures a distinct separation between the first and second stop without relying on a heavier spring.

It requires lower insertion and injection forces for tips to attach and detach. 

Lightweight, Autoclavable and fits universal tips:  With Accumax Micropippettes unlike standard type, there is increased repeatability and decreased variation which provides reliable results in important tasks such as PCR, ELISA, and cell culture.

Why Accumax Micropipettes?

Built for Precision – Ensures accurate and reliable liquid handling.

Lowest Plunge Force – Crafted to ensure smooth and effortless operation.

Magnet Assisted Piston – To deliver unmatched precision and consistency.

Easy Tip Ejection – Shock proof tip ejection with unique shock absorbing mechanism.

Versatile range – You can get single-channel or multi-channel types that handle different amounts.

Accuracy and precision are both essential for reliable pipetting. While accuracy ensures you’re close to the target volume, precision guarantees consistency across multiple uses. Accumax Labs micropipettes are designed to excel in both, making them an excellent choice for laboratories that demand precision, reliability, and efficiency.

Upgrade your lab with Accumax micropipettes and experience the difference in performance!

Also Read: Micropipette Guide: Types, Applications and More

Blog Source -- Micropipette Accuracy vs. Precision: What’s the Difference?

[microlitseo]

How to Train New Lab Staff in Proper Pipetting Techniques?

Accuracy and precision are a paramount in any laboratory environment. Research, diagnostics, or industrial processes depend on proper pipetting skills for reliable results and reproducible tests. However, new lab personnel typically have difficulty with the right technique for handling liquids, and it can lead to problems and inefficiency.

To assist novice trainees to become skilled and confident, there needs to be a carefully planned training program. This blog guides you through training practices on how to instruct lab staff in proper pipetting techniques using liquid handling instruments including micropipettes, bottle top dispensers, and pipette fillers.

We also discuss how to choose the most suitable mechanical pipette suppliers to supply high-quality instruments to maximize laboratory efficiency.

Training procedures of new Lab Staff in Pipetting Techniques

Understanding the Basics of Pipetting

Before exposing trainees to equipment, it is necessary to establish a fundamental knowledge of pipetting. These are:

Why is pipetting done in the lab?

The need for precision and accuracy.

The different types of liquid handling devices used in a lab.

Introduction to Different Pipetting Tools

A key element of training involves introducing new laboratory members to a range of pipetting instruments, their uses, and appropriate usage situations.

a) Micropipette

A micropipette is a delicate instrument for the movement of extremely minute amounts of liquid, usually between microlitres and millilitres. Training should comprise:

Correct handling and grip.

Choosing the appropriate volume.

Correct aspirating and dispensing liquid technique.

Prevention of contamination using sterile tips and backflow prevention.

b) Bottle Top Dispenser

For larger quantities, a bottle top dispenser is an essential equipment that enables efficient and safe dispensing of liquids from bottles. Trainees need to learn:

Installation and setting up of a dispenser in the right way.

Liquid volume adjustments.

Maintenance and cleaning of the lab instruments.

c) Pipette Filler

A pipette filler is used to support the pipetting process by managing quantities of fluids, utilizing plastic or glass pipettes. Training must include:

Selecting the right pipette for the experiment.

Regulation suction rate.

Hold firmly to prevent breakage.

Hands-on Training: Pipetting Practice Step-by-Step

Now, after learning about the instruments, it's time to shift to hands-on training. These steps will ensure trainees cultivate proper pipetting techniques:

Correct Setup

Ensure the workplace is clean and neat.

Choose the right instrument micropipette, pipette filler, or bottle top dispenser for the procedure.

Utilize all the calibrated pipettes correctly throughout the experiment.

Hold and Handle

Demonstrate how to hold a micropipette almost vertically.

Teach how to place tips without touching them.

Significant usage of smooth and even plunger pressure.

Aspirating Liquid

Let the pipette tip below the surface of the liquid.

Push and release in movement to move the plunger slowly and smoothly.

This aspirating process will reduce the formation of bubbles in the solution.

Dispensing Liquid

Hold the tip through the brim of the receiving vessel.

Dispense the liquid slowly and withdraw the tip smoothly.

Utilize the second stop of the plunger to provide a complete liquid release.

Proper Disposal and Cleaning

Properly dispose of tips in appropriate biohazard waste.

Clean and store liquid handling equipment properly to prolong its lifespan.

Common Pipetting Mistakes and How to Prevent Them

During training, some required points must be highlighted among the common pipetting mistakes and solutions. Such as,

Unreliable Pipetting Techniques

This results in variations in volume and incorrect results. To counter this, it is important to get lab staff to develop a habit of maintaining a consistent grip, maintaining a constant angle of pipetting, and consistent speed in aspirating and dispensing liquids. These small yet important habits can enhance reproducibility and reduce errors.

Picking the Wrong Volume

During pipetting, no one desires to jeopardize experimental outcomes. To answer this, students should be instructed on how to properly set and calibrate volumes on micropipettes and bottle-top dispensers. Demonstrations by hand can reinforce correct techniques so that the desired volume is precisely measured each time.

Using the Wrong Type of Pipette

This is also a frequent problem that compromises accuracy. Laboratory procedures demand certain pipettes, and making the right choice is imperative. Training must incorporate learning how to select the correct pipette filler or mechanical pipette supplier equipment for the requirements of the experiment. Know-how about the differences among various pipetting equipment avoids unwarranted mistakes and proper use in laboratory operations.

Sample Contamination

It can be a severe issue that would undermine results and impact research integrity. While experimenting, contamination may often result from the repetition of using a single pipette tip for several samples, if liquid is touched, or while pipetting in a non-sterile area.

This way of contamination can be prevented by following best practices such as replacing the pipette tip between experimenting samples, not touching liquids directly, and working within the sterility wherever needed. 

Choosing the Appropriate Mechanical Pipette Supplier

Maintaining accuracy and longevity of equipment in the lab can be helpful for seamlessly conducting experiments. Pipette vendor selection can overview different factors to consider, including precision and calibration requirements, longevity, ease of maintenance, and availability of instrument spares.

Compatibility with laboratory protocols also allows for smooth integration into workflows. Proper selection of vendors by laboratories allows for the use of reliable equipment to support accurate experimentation.

Embracing Regular Competency Assessments

Of all the options, routine testing of the equipment is necessary. The routine tests can be followed as practice drills with dye solutions to check pipetting procedures, observation and feedback training to correct in real time.

Conducting these tests in between the experiment workflow, may ensure laboratory personnel remain competent and constantly improve their pipetting techniques, leading to more enhanced experimental results.

Conclusion

The training for pipetting techniques of new lab staff is fundamental to maintaining the efficiency and accuracy of laboratory operations. Properly laid out training programs on different instruments for handling liquids, such as micropipettes, bottle top dispensers, and pipette fillers, to prevent duplicate errors and confidence among trainees.In addition, sourcing high-quality instruments from reputable mechanical pipette companies like Microlit can play a significant role in providing accuracy in lab operations. Through support of best practices, provision of hands-on training, and regular competency assessment, labs are able to maintain high levels of accuracy and reliability in their research and testing activities.

[elizashields]

Micropipette NMP-200

Labnics Micropipette provides an adjustable volume range from 1000 to 10,000 μL, ensuring precise liquid dispensing for various lab applications. It features smooth plunger action, ergonomic design, and easy calibration and complies with ISO8655/DIN12650 standards for reliable performance.

[zjhq]

1. Precise and accurate. This laboratory instrument is designed with an advanced spring mechanism for unimpeded movement. It provides clear, smooth liquid release with high precision.

2. Ergonomic and intuitive operation. Transfer liquids with ease with our lightweight micropipettes. Its large grip provides a great grip. In addition to the soft grip, our laboratory pipettes have a soft plunger for increased user comfort when pipetting for extended periods of time.

3. Clean, reliable results. Our laboratory pipettes are half autoclavable at 121°C and 15 PSI for 10-15 minutes. They ensure maximum sterilization to prevent any cross-contamination in precision laboratory applications.

4. Complete packaging. Each pipette box includes a calibrated micropipette, 1-2 compatible pipette tips, calibration tools, ISO 8655 calibration certificate (valid for 1 year), micropipette holder and complete user manual .

5. Quality History. With more than 30 years of experience in the life science industry, SHENGCHUANG has created reliable products such as micropipettes, bottle top dispensers, electronic burettes and other laboratory instruments and equipment used by professionals in over 45 countries .

[microlitusa]

Micropipette Set | Pipette Starter Kit | Microlit USA

Microlit offers you a set of compact micropipette that is used as a adjustable volume pipette. The set includes 3 adjustable micropipette having different range of liquid volume, universal top cone compatible with most internationally accepted tips and fully autoclavable at 20° C, 15psi. For details, call us at +1(732) 321-0852 or visit the website https://www.microlit.us/product-category/pipette-sets-kits/

[angiplastpvtltd]

Adjustable Micropipette Manufacturers in India

Angiplast Pvt. Ltd. is one of the best Adjustable Micropipette Manufacturers, Exporters, And Suppliers in India at a reliable rate. Our adjustable micropipette is sturdily designed with different volumes and sizes. It is easy to use, highly accurate, and uses standard micropipette tips. The volume is easily selected by twisting the top. The lightweight design and tip ejector make operation fast & easy.

[labotronicsscientific]

Adjustable Volume Micro Pipette

Labotronics adjustable volume micro pipette is a single-channel micropipette with a pipetting range 0.1~2.5 µL.It offers adjustable volume with a push-button and comfortable finger support.Disposable tips are attached securely to the tip cones and it is constructed with chemical-resistant materials to ensure durability.It has 2 press clicks for extracting specific volume of liquid and dispense it at desired location. It is autoclavable at 121℃ under 1 bar pressure for 20 minutes. Read more

[lab-instrument]

Manual Digital Adjustable 12 Channel Option Multichannel Pipette MicroPipette Lab Equipment M12 Series https://a.aliexpress.com/_mMV5cEO https://www.instagram.com/p/CqHeguzpTb5/?igshid=NGJjMDIxMWI=

[accumax]

Micropipette Guide 2024: Types, Applications and More

Micropipettes or pipettes, are instruments used to measure liquid ranging between volumes of 1-10000 µl and transfer it from one sample container to another. This is a basic liquid-handling instrument for almost all scientific laboratories.

Types of Micropipettes

There is no 1 way to classify micropipettes. It can vary in a number of ways.

1. Number of Channels

Single Channel Micropipettes

A single-channel micropipette has only 1 channel to aspirate and dispense the liquid. It means you can handle only one sample at a time.

Multi-Channel Micropipettes

Multi-channel micropipettes can handle 8, 12 or 16 samples in one go. It can attach multiple tips at the same time and you can get the work done faster especially if working in high-throughput labs.

2. Volume Adjustment

Fixed Volume Micropipettes Here the volume a pipette can aspirate and dispense remains the same and you don’t have the option to adjust or choose between a range. They offer consistent and accurate results for repetitive pipetting.

Variable Volume Micropipettes

Variable volume pipettes give you the flexibility to choose the volume you want to pipette (within the given range). You need to set the volume manually on the dial. High-performance pipettes also come with a volume lock feature for enhanced safety and reliability.

3. Operating Mechanism

Mechanical Pipettes

These are the standard pipettes widely used in all laboratories. Mechanical micropipettes operate on a piston-driven system, where users manually set the desired volume using a dial and apply thumb pressure on the plunger to aspirate and dispense liquids.

Electronic Micropipettes

Electronic micropipettes are more expensive than mechanical ones because they have digital controls, programmability and eliminates the element of human error to a certain extent. It has an electronic display and is ideal for high-throughput labs where reproducibility is paramount.

Components of Micropipette

Plunger

The plunger is one of the main components of the micropipette. Use your thumb to press down on the plunger to aspirate and dispense the liquid.

Then, with a firmer push, sometimes called the “blow-out stop,” it ensures a thorough expulsion of any remaining liquid, guaranteeing accurate measurements—a two-step process of liquid control.

Ergonomics are a key point here since lab professionals will be pipetting repeatedly for long hours. A low-force mechanism which does not require excessive plunge force, will minimize the RSI.

Volume Adjustment Dial

By twisting the volume adjustment dial, you dictate the micropipette’s plunger movement, determining your experiment’s liquid dosage. In micropipettes with adjustable volumes, this feature offers precise measurement control, no matter how small or large the quantity is.

Tip Ejector

Keep your hands and micropipette clean by disposing of used tips promptly. Utilize the convenient tip ejector button to effortlessly remove micropipette tips, ensuring a fuss-free and contamination-free experiment environment.

Tip Cone The tip cone, also known as the shaft, is the crucial component of a micropipette where the disposable tip is inserted. Its primary function is to ensure a snug fit for the tip, ensuring precision in measurements and preventing air leakage. Its adaptable shape accommodates various sizes and styles of tips, allowing for versatile and secure usage without concerns of detachment or disruptions.

Calibration Screw Inside the micropipette lies a crucial component, the calibration screw. This is what makes accuracy possible. Twisting this tiny screw adjusts the liquid output, fine-tuning the micropipette’s performance. Regular checks and tweaks, as advised by the manufacturer, ensure precision in your measurements, keeping everything flowing smoothly.

Applications of Micropipettes in Laboratory

Micropipettes are used to measure any small amount of liquid samples for testing and research. They are crucial in lab settings like molecular biology and diagnostics, precisely transferring tiny liquid volumes, facilitating diverse experiments. Mastery of their principles is key to effective scientific research and analysis.

Some common applications include:

1. Molecular Biology 2. Biochemistry 3. Cell Culture 4. Microbiology 5. Analytical Chemistry 6. Clinical Diagnostics 7. Pharmaceutical Research

How does a Micropipette work?

Micropipettes operate on the principle of air displacement. They consist of a plunger connected to an internal piston, which moves to two distinct positions: Filling Position: When the plunger is depressed to the first stop, the internal piston displaces a volume of air equal to the desired volume shown on the volume indicator dial. This creates a vacuum, drawing the liquid into the tip. Dispensing Position: The second stop on the plunger is used solely for dispensing the contents of the tip without drawing in additional air.

How to use a micropipette?

1. Start with choosing the right micropipette and micropipette tips

Select the one that is best for your application. While pipettes are similar in the way they function, what sets them apart is the accuracy and precision of the measurement, ergonomics and general durability of the instrument.

Set the volume based on your requirement and ensure the tips match the volume of the pipettes.

2. Attach the micropipette tip to the micropipette

Don’t use excessive force here because good quality pipettes will be quick and seamless to attach to the tips and should provide a leak-proof seal.Immerse the pipette in the liquid at 90 degrees Be mindful of your posture and keep the position upright. Aspirate and dispense 2-3 times before actually measuring the liquid

3. Forward or Reverse Pipetting

First let’s talk about forward pipetting:To aspirate the liquid in the tip, press the plunger to the first stop. Immerse the pipette tip vertically in the liquid. Slowly release the plunger while the tip is immersed. The liquid will be aspirated into the pipette tip. To dispense the liquid, place the tip on the inner wall of the receiving vessel at a steep angle Slowly press the plunger to the first stop to dispense the liquid. To empty the tip completely, press the plunger to the second stop.

Now for reverse pipetting

The reverse technique is suitable for dispensing reagents/solutions that have high viscosity or a tendency to foam easily. It is also recommended for dispensing very small volumes.To aspirate the liquid in the tip, press the plunger to the second stop and immerse the pipette tip vertically in the liquid. Slowly release the plunger while the tip is immersed. The liquid will be aspirated into the pipette tip. To dispense the liquid, place the tip on the inner wall of the tube at a steep angle. Slowly press the plunger to the first stop. Finally, eject the tip and dispose it off

Calibration of Micropipettes

Calibration is conducted through gravimetric testing, which involves weighing the amount of pure water delivered in a single operation of the pipette. The obtained mass is divided by the density of water to determine its volume. Variable volume pipettes should undergo testing at three or more points across their designated range, typically at maximum volume, 50% of maximum volume, and the lower limit of their range.

Here’s a general guide on how to calibrate a micropipette:

1. Gather MaterialsMicropipette(s) to be calibrated Appropriate pipette tips Distilled water or a calibration solution Weighing balance with appropriate accuracy (usually in milligrams) Gloves and lab coat for safety

2. Prepare the Micropipette Ensure the micropipette is clean and free from any residue. Attach a fresh and compatible pipette tip to the micropipette.

3. Pre-Wet the Pipette Tip (Optional) For some micropipettes, pre-wetting the tip with the liquid being used can help ensure accuracy. Follow the manufacturer’s recommendations regarding pre-wetting.

4. Prepare the Calibration Solution Use distilled water or a calibration solution recommended by the micropipette manufacturer.

Ensure the calibration solution is at room temperature to minimize density variations.

5. Set the Micropipette to the Desired Volume Adjust the micropipette to the volume you want to calibrate (e.g., if calibrating a 10-100 μL micropipette, set it to 50 μL).

6. Dispense Liquid into a Weighing Boat or Container Dispense the liquid from the micropipette into a weighing boat or a container placed on a weighing balance.

Note down the initial weight (W1) of the liquid dispensed.

7. Weigh the Dispensed Liquid Carefully weigh the liquid dispensed using the weighing balance. Ensure the balance is calibrated and accurate.

Record the final weight (W2) of the liquid.

8. Calculate the Dispensed Volume Subtract the initial weight (W1) from the final weight (W2) to determine the weight of the liquid dispensed (W).

Convert the weight of the liquid dispensed to volume using the density of the liquid or the known density of the calibration solution.

Calculate the actual volume dispensed using the formula:

9. Compare with Expected Volume Compare the calculated volume dispensed with the expected volume (e.g., 50 μL for a 10-100 μL micropipette). Calculate the percent error to assess the accuracy of the micropipette calibration:

10. Adjust if Necessary If the percent error is within an acceptable range (typically ±2-5%), the micropipette is calibrated. Otherwise, adjustments may be needed. Consult the micropipette’s user manual for instructions on how to adjust the volume settings. Adjust carefully and recheck the calibration until the desired accuracy is achieved.

11. Record Calibration Data Keep a record of the calibration process, including the micropipette serial number, date of calibration, volume settings, calibration solution used, measured weights, calculated volumes, and any adjustments made.

12. Final Checks After calibration, perform a final check to ensure the micropipette is dispensing accurately and consistently across the volume range.

When is micropipette calibration required?

Micropipette calibration is typically required in the following situations:

Initial Use

New micropipettes should be calibrated before their initial use to ensure accuracy and precision.

Scheduled Calibration

Regular calibration intervals are recommended to maintain the accuracy of micropipettes over time. The frequency of calibration depends on factors such as the frequency of use, the criticality of the measurements, and the manufacturer’s recommendations.

After Maintenance or Repair

Calibration should be performed after any maintenance or repair work on the micropipette to verify that it meets the required specifications.

Change in Operating Conditions

If there is a significant change in the operating conditions, such as temperature or altitude, recalibration may be necessary to account for these factors’ effects on the micropipette’s performance.

Compliance Requirements

Laboratories may have regulatory or quality assurance requirements that mandate regular calibration of micropipettes to ensure traceability and compliance with standards.

Where do we get the best micropipette for the lab?

When purchasing a micropipette for your lab, consider key factors such as accuracy, precision, ergonomics, and ease of maintenance. Research the brands and models, compare specifications, and read user reviews to make an informed decision. Evaluate additional features like adjustable volume settings and compatibility with automation systems. Set a budget and balance costs with desired features. Check warranty coverage and customer support options for added peace of mind.

Cleaning and Maintenance of Micropipettes

1. External CleaningRemove and Clean the Tip Ejector: Begin by detaching the tip ejector and giving it a thorough wipe-down.

Wipe Down All Exposed Surfaces: Take a lint-free cloth or tissue and carefully wipe all visible parts of the micropipette, including the body, buttons, operating rod, and tip holder. Be diligent in cleaning any scuffs, marks, or accumulated debris in hard-to-reach areas.

Use a Brush for Stubborn Debris: If there are persistent stains or dirt, consider using a soft-bristled brush to gently scrub the affected areas.

Reassemble and Allow to Dry: Once the exterior surfaces are clean, reattach the tip ejector and ensure it is securely in place. Leave the pipette to air dry completely before further use. Final Wipe with Cleaning Solution: Finish the cleaning process by wiping down the outer surfaces once more with a cleaning solution to remove any remaining residue. Allow the alcohol to evaporate fully before returning the pipette to service.

2. Internal Cleaning

Cleaning the inside of a pipette should be handled by trained personnel to avoid incorrect reassembly, which can damage the micropipette and affect its performance, leading to decreased accuracy and potential leakage.Disassemble the Micropipette: Carefully take apart the pipette, placing the upper part in a clean, dry area.

Wipe with Alcohol-Coated Wipes: Use alcohol-coated wipes to thoroughly clean the entire interior, including the body, connecting nut, tip holder, O-ring, seal, and the stainless steel surface of the piston. Ensure the piston is completely dry to prevent corrosion.

Allow Alcohol to Evaporate: Let the alcohol evaporate fully from the interior of the pipette. Check for Lubrication Needs: Refer to the instruction manual to determine if any parts, like the piston assembly and seals, require lubrication. Follow the manual’s guidance for reassembly, ensuring proper alignment and placement of components.

Maintaining Micropipettes

When the pipette is not in use it should be stored in an upright position. The pipette should be inspected prior to use each day for any dust or contamination on outside surfaces. Special attention should be given to the tip cone. No solvent other than isopropanol should be used to clean the pipette. If the pipette is used daily, an internal parts inspection should be performed every three months.

Choosing the right micropipette for your applicationEnsure that the micropipette can accommodate the desired range of liquid volumes for your pipetting needs.

Verify if the micropipette features a universal tip cone to accommodate various types of pipette tips.

Check if the micropipette is autoclavable at the necessary temperature to ensure proper sterilization.

Check if the micropipette is UV resistant so that they can be kept inside the hood even when the UV mode is on.

Assess the ergonomic design of the micropipette for smooth and comfortable handling during use. Confirm if the micropipette is calibrated to guarantee precise dispensing of liquids.

Evaluate the accuracy and precision of the micropipette’s readings to ensure compliance with ISO standards.

Ergonomics is a key factor in choosing a pipette because repetitive strain injury is common amongst lab personnel who pipette regularly. Low-force tip ejection and minimal plunge force are crucial.

Accumax Lab Devices specializes in manufacturing high-precision liquid handling instruments for top-tier laboratories worldwide. With a focus on innovation, it offers an advanced range of micropipettes designed to enhance user experience within real-world laboratory settings. Especially our range of FAB and FAB LF pipettes, which are specially designed for accuracy and precision with excellent ergonomics to elevate your pipetting experience like never before.

Micropipette FAQs

1. Can I use any brand of pipette tips with my micropipette?

Whether you can use any brand of pipette tips with your micropipette depends on its tip cone design. If your micropipette has a universal tip cone, it means it’s compatible with a wide range of international pipette tip brands, as long as they’re suitable for your micropipette’s volume capacity.

2. What’s the best way to sterilize my pipette before use?

To clean your micropipette before using it, first, check if it can be sterilized using an autoclave. If it can, follow the instructions in the manual to know the right temperature and duration for sterilization. Make sure to consider the type of liquid you’ll be using it for.

3. Is there a simple way to check if my micropipette is calibrated correctly?

Set it to the usual volume, then dispense water five times. Weigh what you piped out on a scale. If it matches up nicely with the ISO standard, your micropipette is good to go. If not, it’s time for a recalibration.

4. How frequently should I recalibrate my micropipette?

For regular use, it’s good to check your micropipette’s calibration every 3 to 6 months. Following the ISO 8655 standard, it’s recommended to have it calibrated annually.

5. How to adjust the volume of a micropipette?

To adjust the volume on your micropipette, look for the display showing numbers indicating the volume range. If you have a fixed-volume micropipette, the range is predetermined. However, if you have a variable volume micropipette, you can adjust it within the given range by using the rotational dial located at the top of the micropipette plunger. Alternatively, you can consult the manual for specific instructions on changing the volume.

6. Why is it important to avoid touching the tips of the micropipette?

When you touch the tips of a micropipette, you risk transferring oils and other substances from your fingers onto them. This can interfere with the accuracy of volume measurements and potentially contaminate your samples. To maintain precision and avoid contamination, it’s best to handle the micropipette tips only with the instrument itself.

7. What happens if I release the plunger of the micropipette too quickly?

Releasing the micropipette plunger too quickly can lead to inadequate liquid draw up and dispensing, causing potential inaccuracies in your measurements.

8. What should I do if my micropipette isn’t working right?

If your micropipette isn’t working properly, it’s time for some troubleshooting. Start by double-checking if it’s properly calibrated and if the volume setting is correct. Ensure that the pipette tips are securely attached and not damaged. If the issue persists, you might need to clean or maintain the micropipette according to the manufacturer’s instructions. If all else fails, it might be time to consult with a colleague or contact technical support for further assistance.

9. Can my micropipette handle different types of liquids?

Your micropipette is designed to handle a variety of liquids, whether they’re watery solutions, viscous substances, or even oils. As long as you’re using the appropriate tip size and technique, your micropipette can smoothly pipette different types of liquids.

This blog originally posted here: Micropipette Guide 2024: Types, Applications and More

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The Future of Pipetting: Trends and Innovations in 2025

While working in a laboratory, pipetting is observed as a simple yet crucial laboratory technique. This has also undergone a remarkable evolution over the years. In the initial introduction of micropipettes, it was a mouth pipetting technique to the advent of manual and electronic pipettes. 

This has also been observed with evolution, the quest for accuracy widened. This also made lab technicians crave for accuracy, efficiency, and user-friendliness. It also played a major role in driving innovation in this field. 

As we step into 2025, there are several exciting trends and innovations which will reshape the overall future of pipetting. This blog is all about the new innovations that are integrated in the laboratory for pipetting which makes experiment procedures easy and seamless for the technicians.

Innovations in Laboratory projecting Future of Pipetting

Without further ado, let's have a look on a latest additions in the laboratory liquid handling equipments for the future of pipetting, 

Smart Pipettes

One of the most significant trends in pipetting is the emergence of smart pipettes. These advanced pipettes are equipped with sensors, microprocessors, and wireless connectivity, enabling lab technicians to collect and transmit data in real-time. This data can include information about pipetting volumes, speeds, and even the type of liquid being handled.

Smart pipettes offer several advantages such as enhancing accuracy and reducing errors by providing feedback to the user and automatically adjusting for variations in liquid viscosity or density. They can also align workflows by integrating with laboratory information management systems and other software platforms. This can also further allow for seamless data transfer and analysis, reducing the need for manual record-keeping.

In the coming future, as observed, smart and mechanical pipette are likely to become even more sophisticated, with features such as voice control, augmented reality interfaces, and artificial intelligence-powered guidance. These advancements will further enhance the user experience and make pipetting more efficient and intuitive.

Automation

Among all the innovations, automation can be termed as one of the key trends that can play a significant role in transforming the landscape of pipetting. Automated liquid handling systems are now widely used in high-throughput applications like drug discovery, genomics, and proteomics.

You might think that automated pipetting systems might affect experiment procedures. But these systems can perform a variety of pipetting tasks with minimal human intervention, freeing up researchers and technicians to focus on more complex and creative aspects of their work.

The future can observe development of more compact and affordable systems, as well as the integration of robotics and artificial intelligence. These advancements will make it possible to automate even more complex pipetting tasks, such as cell sorting and sample preparation for next-generation sequencing.

Miniaturization

Similar to automation, it is miniaturization which makes research more focused on analyzing smaller and smaller samples. There is a growing need for pipetting solutions that can handle microliter and nanoliter volumes with precision. 

Their micropipette devices can be helpful devices to manipulate and analyze tiny volumes of liquids, opening up new possibilities in fields such as single-cell analysis and point-of-care diagnostics. In future, we can expect observations on further development of the smallest of all pipetting technologies. 

The future of pipetting can be perfect with the use of acoustic dispensing and inkjet printing. These techniques will enable even more precise and efficient handling of small volumes, paving the way for new discoveries in various fields of research.

Ergonomics and User Experience

The accuracy and efficiency can be seen as critical points while working on pipetting methods in the laboratory. Along with this, the importance of ergonomics and user experience should not be overlooked. If the pipetting tasks are not in an ergonomic situation, this can lead to musculoskeletal disorders and other health problems. 

Looking towards ergonomic structure and user experience can play a significant role in designing pipettes that are comfortable to use. In the coming years, we can observe more emphasis on ergonomic design in pipetting. This can further include features like adjustable pipetting force and intuitive user interface, it can also keep the hand movement ergonomic and keep your wrist safe from jerks and muscle tension.

Sustainability

World is moving towards sustainability, this is also developing awareness of environmental issues, which is further increasing the focus on sustainability even in the laboratory. This also includes reducing the use of disposable plastics and minimizing waste. 

In the laboratory while using pipettes, this translates to the development of more sustainable pipettes and tips. Manufacturers are exploring the use of biodegradable and recyclable materials as well as developing systems for reusing pipette tips. Along with this, using them can save much time in preparing new setup, at times which can affect the experiment accuracy.

This is also projecting towards the future, which is to expect innovations in sustainable pipetting that includes the use of closed-loop systems that minimize waste and conserve resources. It is also an enhanced way to pipetting, further improving the laboratory standards.

Conclusion

With all the innovations and transformations, the future of pipetting seems bright. There are various trends and innovations while projecting a transformation that is also elevating the experiment procedures conducted by the lab technicians. 

The process of including smart pipettes with suitable automation, and following ergonomic techniques, these can drive progress in the laboratory industry. Further they can also play a major role in enhancing the accuracy and efficiency throughout the experiment procedure. 

As we move forward, we can expect to see pipetting become more accurate, efficient, user-friendly, and environmentally responsible. These advancements will not only benefit researchers and laboratory professionals but also contribute to breakthroughs in various fields of science and medicine. Are you a laboratory technician and looking for pipetting techniques that can improve your precision standards in the laboratory. Without roaming in the maze of searching for perfect instruments, check out the best micropipette brand in India, Microlit for your suitable pipettes. They can provide you with a wide range of pipettes, which can enhance your experiment standards.

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Micropipette NMP-113

Labnics Micropipette ensures precise liquid handling with a volume range of 0.1-2.5 μL and 0.05 μL increments. Key features include a low-force tip ejector, easy calibration, ISO 8655 compliance, a plunger button for volume adjustment, and ergonomic finger support for comfort.

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(1)Before cleaning the micropipette, ensure that it is not in use and that there is no liquid in the tip.

(2)Disassemble the micropipette by removing the tip, and then remove the plunger mechanism and shaft from the body of the pipette.

(3)Clean the exterior of the micropipette body with a damp cloth or a cotton swab soaked in a mild detergent solution. Be careful not to get any liquid inside the micropipette.

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Angiplast Pvt. Ltd. is one of the best Adjustable Micropipette Manufacturers, Exporters And Suppliers in India at reliable rate.