#human papillomavirus

[millennialskin]

Warts: Are They Contagious?

Warts are a common skin condition that affects many people at some point in their lives. Despite their prevalence, myths and misconceptions about what causes warts and how to get rid of them abound. In this blog post, we’ll clear up the confusion, delve into the science of warts, and explore proven treatment options as well as preventive measures. What are Warts? Warts are growths on the skin…

[familydocblog]

Gardasil: Your Superhero in the Battle Against HPV

Unlock the Power of Gardasil: Your Shield Against HPV! Dive into a world where prevention meets empowerment. Stay informed, stay protected!

HPV (human papillomavirus) is the most common sexually transmitted infection. Nearly all sexually active individuals will contract one or more strains of HPV at some point. While most HPV cases resolve on their own, infections from high-risk strains can lead to serious health issues if left untreated. This is where the Gardasil vaccine comes in. HPV is a Common Virus HPV is primarily spread…

[worldhepatitisday]

Hepatitis C and HIV detection by blood RNA-sequencing in cohort of smokers.

Studies of viruses in human tissues have helped to better understand the human virome and its role in human disease. Through secondary use of human RNA and DNA sequencing to detect viruses, evidence has emerged regarding a healthy human blood virom. In a study of the peripheral blood DNA virome in 8,240 individuals, Moustafa and colleagues repurposed human WGS data and were able to map the WGS data to sequences of 94 different viruses, including 19 human viruses, and observed differences in virus profiles across age, sex and ancestry. Human Cytomegalovirus (CMV), HHV-6A, HHV-6B, Epstein–Barr virus (EBV) and Torque Teno Virus (TTV), Anellovirus) were among those detected. In a multi-tissue study repurposing RNA sequencing (RNA-seq) data by Kumata and colleagues, EBV, CMV, TTV and human papillomavirus were among the viruses observed in blood.

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Original article submitted:

“Let’s stop spreading fake news.”

This is the appeal of the panel of doctors and specialists who spearheaded the freshly held health talk on cervical cancer titled #TimeToTalkAboutHPV: A health forum on HPV prevention and cancer control. Organised by the Cervical Cancer Prevention Network of the Philippines (CECAP), together with the Asia & Oceania Federation of Obstetrics & Gynecology (AOFOG), the Philippine Obstetrical and Gynecological Society (POGS), and MSD in the Philippines, the media forum aims to serve as a reminder that cervical cancer is preventable with regular screening tests and the HPV vaccination.

“We should stop spreading wrong information that cervical cancer immediately means a death sentence. We must stop encouraging wrong beliefs about the disease, screening and the vaccine,” patient advocate Carmen Auste appealed to the media.

Cervical cancer is largely preventable through both vaccination and screening for precursor lesions (pap smear at least every three years and HPV DNA testing for women starting age 30), with appropriate follow up and treatment. With access to accurate information, preventive services, and routine gynecological care, most cases of the disease can be prevented and successfully treated at an early stage.

In spite of this, cervical cancer ranks as the 2nd most frequent cancer among women in Philippines and the 2nd most frequent cancer among women between 15 and 44 years of age. Current estimates indicate that every year 7,897 women are diagnosed with cervical cancer and 4,052 die from the disease.

Cervical cancer develops at the entrance to the uterus from the vagina and around 99 percent of the cases are linked to HPV or human papillomaviruses. Modes of transmission include sexual contact, skin-to-skin contact and rarely, through objects exposed to the virus. 

It’s a highly-treatable disease if detected at its early stages. The precancerous stage provides ample window for detection and treatment, and it could take as long as 30 years before it reaches malignancy.  However, it is one of the most common type of cancers and common cause of cancer-related deaths worldwide, affecting mostly young, uneducated women from poor countries. 

But more recently, COVID-19 has taken a toll on women’s health as studies have shown a gap in missed routine preventative exams and screening visits. “I think the world has been focused on Covid for the past 2 ½ years and we have overlooked other health concerns,” said Dr. Anna Lisa Ong-Lim, professor and chief of division of infectious and tropical disease in Pediatrics University of UP Manila College of Medicine. “It is only recently when vulnerabilities to vaccine-preventable diseases are being noticed once again.”     

Things you need to know about HPV

One life-altering issue that deserves focus is the huge burden that continues to threaten women and men, including teenagers worldwide, caused by the human papillomavirus (HPV). “HPV is a virus that causes a wide-range of diseases,” said MSD executive director of medical affairs for vaccines and infectious disease Dr. Mel Kohn.

“Apart from cervical cancer, the 2nd leading cancer for Filipinas, HPV can give men head and neck cancer, anal cancer for both sexes and a variety of less common but also devastating kinds of cancers,” he enumerated. Examples are vaginal and vulvar cancers, and penile cancer.

“Genital warts, while it doesn’t kill you, can be quite devastating,” interjected Dr. Kohn. “It is quite common and very difficult to eradicate. Imagine the psychological toll on the patient. Again, prevention is the best approach here.”

HPV is common. It is passed from one person to another during sexual contact. “It’s a quiet epidemic unlike COVID,” he warned. Unlike the measles that have obvious expression, “you don’t immediately see it when you meet somebody but it’s there and has been growing rather insidiously.”

The Philippines has a population of 37.8 million women ages 15 years and older who are at risk of developing cervical cancer. About 2.9% of women in the general population are estimated to harbor cervical HPV-16/18 infection at a given time, and 58.6% of invasive cervical cancers are attributed to HPVs 16 or 18.

Although some of the infections from this commonly occurring virus with more than 100 types usually go away on their own, at least 14 types of HPV have been found to be cancer-causing.

The age indication for HPV vaccines is as young as nine years old to both girls and boys. Teens and young adults through age 26 years who didn’t start or finish the HPV vaccine series also should have HPV vaccination. Women up to age 45 may be eligible for vaccination after discussing with their provider.

According to Dr. Ong-Lim, they are targeting the young ones because of their increased susceptibility to infections.

“That particular age group demonstrates optimal immune response. Also, only two doses are needed to achieve protection,” she shared.

But more importantly, giving the vaccine at a younger age ensures that they are already protected before they become sexually active. “HPV vaccines work best when given before exposure to the virus. We must try to catch that window when the immune system really responds very well to it,” explains Dr. Ong-Lim

Manila Declaration: Call to Action Against Cervical Cancer chair and practicing OP-Gynecologist Dr. Jean AnneToral mentions that the young and adult fertility study done recently, indicates that the average age Filipina women become sexually active is 18.2 years old. “Giving the vaccine at age 9-15 would be beneficial as there is no life event that exactly pinpoints exposure to HPV apart from age of sexual debut,” she said.

There will be seven to eight out of 10 women who would be exposed to HPV at one point in their life, “But not all women will develop cervical cancer,” assures Dr. Toral. The probability of HPV exposure developing into cancer increases if a patient smokes, is exposed to other sexually-transmitted diseases and has HIV.

School-based HPV vaccination

As part of the government’s effort to protect children and adolescents from vaccine-preventable diseases, the Department of Health together with partner agencies, rolls out the School-Based Immunization (SBI) Program.

The SBI Program includes measles, rubella, tetanus, diphtheria (MR-TD) and human papillomavirus (HPV) vaccines that are administered to eligible students in public elementary schools. The inclusion of HPV vaccination in the SBI Program aims to protect young women from cervical cancer later in life, among other diseases associated with HPV.

Under the DOH’s SBI Program, HPV vaccination is given to grade 4 based on DOH’s recommended age group to receive the two doses of HPV vaccine, six months apart, for protection against cervical cancer.

Prior to administering the vaccine, parents’ consent must first be obtained by school officials. That is why vaccination education campaigns usually highlight the role of parents in fortifying the health shield of their children through timely vaccination against diseases.

Due to the COVID-19 pandemic, the HPV vaccination, which was formerly delivered through the SBI Program is now being shifted as part of the Community-based Immunization to be able to still deliver HPV vaccination to young girls amidst the pandemic to protect them against cervical cancer and other HPV-related diseases and cancers.

Towards a cervical cancer-free future

The elimination of cervical cancer has been defined as achieving an incidence rate low enough for the disease to be considered controlled as a public-health problem; this threshold has been defined by the WHO as fewer than 4 cases per 100,000 women per year.

To accomplish this, every country must reach and maintain three key targets, within the lifetime of today’s young generation. The first is for 90 per cent of girls to be fully vaccinated against the human papillomavirus (HPV) by the age of 15. The second is to ensure that 70 per cent of women are screened using a high-performance test by the age of 35, and again by age 45. The final target is for 90 per cent of women with pre-cancer to receive treatment and for 90 per cent of women with invasive cancer to have their condition properly managed.

Achieving this vision and each of the elimination targets will require a whole-of-society and multisectoral approach to ensure health systems prioritize women and girls. Individuals, families, communities, , civil society, and government agencies at all levels have a role to play in championing greater awareness, education, and social support.

Auste said that the Philippines is among the countries that declared commitment together with WHO to finally eradicate cervical cancer in the country by 2040, and by 2030 worldwide. “There is already one type of cancer that we can delete or ‘block’ like social media,” she humored. “To attain that goal, we must augment HPV vaccine uptake and educate the Filipinos on HPV, vaccines and cancers caused by HPV,” she said.

Auste mentioned SUCCESS ('Scale-up Cervical Cancer Elimination with Secondary prevention Strategy') project as one of the advocacies recently launched in selected barangays. Led by Expertise France and delivered in collaboration with Jhpiego and Union for International Cancer Control (UICC) in support of WHO, the project aims to deploy innovative solutions to fight cervical cancer in four countries, including the Philippines.

At this critical juncture, we must empower women and rally our neighbors, community leaders, and governments to take action and save thousands of lives. If widespread, high coverage of these interventions can be achieved by 2030 and maintained, research predicts cervical cancer can be eliminated in most countries globally by 2120—avoiding over 63 million deaths of women globally.

Together, let’s commit to women everywhere to end cervical cancer. ###

[lifohealth]

"Understanding Human Papillomavirus Infection: Causes, Symptoms, Treatment, and Prevention"

I. Introduction Human Papillomavirus Infection “HPV infection” is a common sexually transmitted infection caused by a virus that affects both men and women. It is estimated that approximately 79 million people in the United States are currently infected with HPV, with 14 million new infections occurring each year. HPV is spread through skin-to-skin contact during sexual activity, including…

[msdindia]

Types of HPV and what they result in

Each type or quantity of human papillomavirus is distinct. A specific kind of wart that develops from particular HPV kinds is referred to as a “papilloma.”

[shadihelal]

Human papillomavirus (HPV)

Human papillomavirus (HPV) is the most common STD, according to CDC, affecting 79 million Americans, with an estimated 20 million people infected every year. It’s transmitted through skin-to-skin contact and can cause genital warts and cervical cancer. While it’s possible to have HPV without any symptoms, some infected persons experience symptoms; that range from mild to severe. those with no…

[todayhealthlife]

HPV genital warts or the human papillomavirus are among the most common sexually transmitted diseases that infect one’s genital virus. There are more than 40 strains of HPV genital warts.

for more info : https://www.todayhealthlife.com/

[alysonpappas]

How is HPV caused? What precautions to take?

HPV, or human papillomavirus, is currently one of the most common STIs (Sexually transmitted infection) globally. It is usually asymptomatic, and almost everyone (eighty per cent of all sexually active humans) contracts it at some point in their lives.

Contracting HPV increases your risk of developing various types of genital and throat cancers in the future. To protect yourself from this danger, you should take certain precautions while staying protected from other partners who have been exposed to this disease as well. Let us understand HPV and how we can protect ourselves better against it.

What is HPV? HPV stands for human papillomavirus. This is a group of over 100 different types of viruses that spread through sexual activity in humans. In most cases, the body’s immune system clears the virus within a maximum of two years. However, some people who contract this virus will continue to have recurring infections throughout their lives. This is especially common among those who have compromised immune systems like those with HIV/AIDS or undergoing chemotherapy.

Some cases with persistent infections are at a high risk of developing cancer, especially in women. HPV is responsible for virtually all cervical cancer cases. It also contributes 5 per cent to the overall global cancer case count every year.

Types of HPV There are currently over 100 types of HPV identified, and around 80 per cent of all sexually active people will have exposure to at least one type of the virus. Most of these types cause no symptoms, while some are linked to cancers of the cervix, genital areas, mouth, and anal area. Milder forms of infection may not even produce any symptoms. However, if left untreated, some types of HPV can lead to genital cancers.

There are two main types of HPV that are linked to cervical cancer: type 16 and 18. HPV 16 is mostly associated with cervical intraepithelial neoplasia (CIN) or cervical dysplasia, which is a precursor to cervical cancer. CIN is an abnormal growth of cervical tissue that is usually caused by HPV infection. Types 16 and 18 can also cause cancers in the oropharyngeal (back of the throat) and anal areas. Types 6 and 11 are most commonly linked to genital warts.

How do you get HPV? HPV is very easily passed from one person to another during sex, as well as by skin-to-skin contact. You can also get HPV from intimate contact with genital warts or from a wart infection in an HPV-positive partner. This can occur during oral sex, fingering, or even through a wound on your own genitals. If you are not wearing protection, you could get genital HPV infection as well.

Signs and symptoms of HPV infection If you have HPV, there is a chance that you may not even know that you have the virus. The first signs of an HPV infection are usually common genital warts. These may appear as small pink bumps or skin lesions on the vulva, anus, penis, or scrotum. If you experience any of these symptoms, it is important to visit your doctor as soon as possible. These may be signs of more serious conditions like cancers.

Cervical cancer is the most common type of HPV-related cancer. It is caused by types 16 and 18 and typically occurs during the late stages of the virus. Symptoms of cervical cancer include a persistent painful or abnormal discharge from the cervix. Both oropharyngeal and anal cancers are caused by HPV, although the signs and symptoms vary greatly. Oropharyngeal cancer typically causes a sore or lump in the back of your throat, while anal cancer causes a persistent discharge or itching.

Steps to reduce your risk of HPV infection If you have not been diagnosed with HPV, there are certain precautions that you can take to reduce your risk of contracting the virus. These include using condoms every time you have sex, avoiding oral sex with multiple partners, and staying up-to-date on your vaccinations.

If you have been diagnosed with HPV, there are still certain things that you can do to reduce your risk. These include getting your partner diagnosed with the virus, abstaining from sex, and getting vaccinated against the virus.

Conclusion STD/STI prevention is a crucial part of staying healthy, and preventing the contraction of HPV is the only way to protect yourself from this disease. If you have been diagnosed with HPV and want to reduce your risk of contracting other STIs in the future, there are certain precautions that you can take. These include wearing condoms, avoiding oral sex with multiple partners, and getting vaccinated against the virus. Don’t wait; start the preventive process by getting in touch with your doctor today!

[hpv-treatment]

Human papillomavirus is a group of viruses that can lead to skin or soft tissue infections, known as cutaneous HPV.

[wizbloggers-blog]

The study focused on women with a minimum two-year history of persistent high-risk HPV. Patients in the treatment group received an AHCC supplement for six months, followed by six months of placebo. Patients in the placebo group received a placebo for 12 months. The study found that 14 of 22 patients (63.6%) became HPV-negative in the treatment arm.

[korethekiller]

Another one!

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