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Statement from FDA Commissioner Scott Gottlieb, M.D., on agency’s efforts to advance new ways to increase the availability of naloxone as one means for reducing opioid overdose deaths

With the number of overdose deaths from prescription and illicit opioids doubling from 21,089 in 2010 to 42,249 in 2016, it’s critical that we continue to tackle this human tragedy from all fronts – including, and importantly, looking at new ways to increase the availability of naloxone.

This potentially life-saving treatment is a critical tool for individuals, families, first responders and communities to help reduce opioid overdose deaths. We recognize that emergency treatment of known or suspected opioid overdose is an urgent public health priority. And to advance these efforts, there is still a need to improve access to naloxone.

To that end, we’re announcing today an upcoming two-day advisory committee meeting in December to solicit input and advice on strategies to increase the availability of naloxone products intended for use in the community.

At this meeting, we’ll be asking our external advisors from the FDA’s Anesthetic and Analgesic Drug Products and the Drug Safety and Risk Management Advisory Committees to consider various options for increasing access to naloxone. They will help us weigh logistical, economic and harm reduction aspects of different strategies. And we will consider whether naloxone should be co-prescribed with all or some opioid prescriptions to reduce the risk of overdose death.

There is the potential for significant costs and burdens that may be associated with naloxone co-prescribing. These include the direct economic costs to consumers and health systems. They also include practical considerations such as the need for manufacturing volume growth for naloxone, and the risk of drug shortages of this product that could come from a sudden spike in prescribing.

The committee will be asked to evaluate these and other considerations, as part of our effort to consider any potential challenges to wider co-prescribing of naloxone for all or some prescription opioid patients.

December’s public meeting builds on the ongoing work that we’ve undertaken to get this life-saving medication into the hands of those who need it most. When someone overdoses on an opioid, it can be difficult to awaken the person and breathing may become shallow or stop. This can lead to death if there is no medical intervention.

But, if naloxone is administered quickly, it can counter the overdose effects, usually within minutes. Naloxone can save lives. But it’s not a substitute for immediate medical care for a patient who is overdosing on an opioid. Moreover, the person administering naloxone should seek further immediate medical attention on the patient’s behalf.

We’ve been working hard to improve the availability of naloxone products.

In addition to the approval of injectable naloxone for use in a healthcare setting and both prescription auto-injector and intranasal forms of naloxone, which facilitate use by laypersons, we’ve also released draft guidance for industry to facilitate the development of generic naloxone hydrochloride nasal spray.

We’ve also made progress on our work to advance the development of an over-the-counter (OTC) naloxone product as a way to promote wider access to this medicine. Although the auto-injector and nasal spray formulations have instructions for use, they don’t have the consumer-friendly Drug Facts Label (DFL), which is required for OTC drug products. Before submitting a new drug application or supplement for an OTC drug product, companies need to develop this DFL and conduct the required studies to show that consumers can understand how to use the product without the help of a health care professional. We recognized the important public health opportunity to bring naloxone OTC. So, to further encourage companies to enter this space, the FDA created a model DFL and simple pictogram. And we are in the process of conducting label comprehension testing for this product. This is the first time the FDA has proactively developed this OTC framework for a drug as a way to help activate the advance of OTC products. Using this information, naloxone manufacturers could focus their efforts on final label comprehension testing of how well consumers understand product-specific information that hasn’t been already tested on the more general model DFL. We plan to release the results of this work soon.

We plan on discussing the potential development of OTC naloxone at the upcoming meeting. Another topic we plan to discuss is the work that many organizations and local municipalities across the U.S. have done to develop programs for making naloxone available in the community. We hope to glean insight from these efforts to further our own goals at expanding naloxone availability.

We look forward to this important discussion on ways to make naloxone more available to treat opioid overdose. And we are committed working with other federal, state and local officials, health care providers, patients and communities across this country to combat the staggering human and economic toll created by opioid abuse and addiction.

The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nation’s food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.

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Source: https://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm624053.htm

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Frozen Banana “Ice Cream”

Frozen banana ice cream is an excellent alternative to sugary desserts for those who’d like to transition their children to a lower-sugar diet. The natural sugars in the bananas make it sweet enough to pass as dessert for those used to eating sweets, while the complete lack of processed sugars makes it better for our bodies. Try some of the different flavor combinations below–or invent your own!–until you find one that you and your kiddos like. You will be so thankful to have a food that your kids crave and is actually good for them!

Sometimes we eat it as a snack and sometimes it is simply part of lunch, but one thing is always for certain: the bowls are licked clean! It is one of the easiest treats in the world to make: simply peel 2-3 bananas, cut or break them into 1-2 inch pieces, freeze the pieces, and put them in a blender or food processor, and puree until smooth (this amount will make about 2 servings).

If you have a single-serving processor such as a Magic Bullet, like I do, you may have to puree, then stop and shake the container, then puree, then shake the container, and so on until all of the bananas are blended.

It will take the banana pieces at least 4 hours to freeze, so I generally put them in a container in the freezer the day before I plan to make the ice cream. If you’re not the plan-ahead type, simply cut up several bananas once you’re done reading this post and store them in the freezer so they’ll be ready whenever you want to give it a try! Once you use up those banana pieces, refill the container with more pieces and put it back in the freezer for the next time you get a hankering.

My girls and I love to add nut butter to our banana ice cream. We’ve discovered peanut butter and sunflower seed butter to be especially delicious. Adding a tablespoon or two of nut butter to the blender along with the banana pieces adds a bit of fat and protein to make the snack more satiating. Half an avocado, virgin coconut oil, and/or coconut flakes will have the same effect. Other frozen fruits such as blueberries and strawberries taste good too. If you’re sticking with plain bananas, adding a 1/2 teaspoon of vanilla extract and a touch of heavy cream or whole milk will enhance the flavor.

Source: https://www.westonaprice.org/frozen-banana-ice-cream/

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Breakfast cereals: 'Almost zero correlation' between health claims and nutritional content

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Source: https://www.medicalnewstoday.com/articles/325148.php

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Beyond fat and sugar: Diets low in whole grains, fruit and nuts associated with 1 in 5 deaths

The Global Burden of Disease report​​, which tracked consumption trends of 15 dietary factors in 195 countries between 1990 to 2017, concluded that one in five deaths are associated with poor diet.

In 2017, this figure equated to 11 million deaths. More than five million of these occurred among adults under 70 years of age.

In addition, poor diet was associated with 25 million of all disability-adjusted life years (DALYs) among adults during this time.

According to the World Health Organization (WHO), one DALY can be thought of as one year of ‘healthy life’. 

“This study affirms what many have thought for several years – that poor diet is responsible for more deaths than any other risk factor in the world,” ​stated study author Dr Christopher Murray, who heads up the Institute for Health Metrics and Evaluation at the University of Washington.

However, where ‘poor diet’ in the western world has typically been associated with diets high in fat, salt and sugar (HFSS) in recent years, Murray suggested the findings encourage a shift of focus.

“While sodium, sugar, and fat have been the focus of policy debates over the past two decades, our assessment suggests the leading dietary risk factors are high intake of sodium, or low intake of healthy foods, such as whole grains, fruit, nuts and seeds, and vegetables.”​

Expanding policy beyond fat and sugar​

“The paper…highlights the need for comprehensive interventions to promote the production, distribution, and consumption of healthy foods across all nations,” ​according to Murray.

The question here lies in what specific type of ‘intervention’. Campaigns aimed at reducing the consumption of foods high in fat, salt and sugar (HFSS) are already widespread in the western world.

Policymakers in the UK, for example, have challenged food and beverage manufacturers to reduce sugar content in certain processed foods by 20%, and a number of governments across the EU have implemented sugar taxes on sugar-sweetened beverages.

This latest study, however, suggests that greater governmental interest in increasing intake of certain foods – such as whole grains, fruit, seeds and nuts, vegetables and omega-3 fatty acids – could be a valid tool in improving global health.

“Dietary policies focusing on promoting the intake of components of diet, for which current intake is less than the optimal level, might have a greater effect than policies only targeting sugar and fat, highlighting the need for a comprehensive food system interventions to promote the production, distribution, and consumption of these foods across nations,” ​write the study authors.

What are we eating too much of? And too little of?

Per the report findings, 11 million deaths and 255 million DALYs were attributable to dietary risk factors in 2017:

High intake of sodium​ was associated with three million deaths​ and 70 million DALYs​

Low intake of whole grains​ was associated with three million deaths​ and 82 million DALYs​

Low intake of fruits was associated with two million deaths​ and 65 million​ DALYs​

At the other end of the spectrum, 2017 saw daily intake of unhealthy foods exceed optimal levels around the world:

Consumption of sugar-sweetened beverages​ was an alarmingly 49% higher​ than the optimal intake (3 g)

Intake of processed meat​ was 90% greater​ than the optimal amount (4 g)

Consumption of sodium​ was 86% higher​ than the optimal intake (6 g)

Intake of red meat​ was 18% higher​ than the optimal intake (27 g)

A call for governmental action has also been made by health campaign group Action on Salt, which suggested The Lancet ​publication was a “wakeup call” ​for policymakers. The group has similarly urged the food industry to play its part in reducing salt intake globally.

“We’ve known the impact of salt on health for a long time now, but it is inexcusable that three million deaths each year are still caused by a high salt diet.​

“Reducing salt is the most effective measure to reduce the number of people dying or suffering from strokes or heart disease,” ​said nutritionist and campaign manager Sonia Pombo.

Source: The Lancet​Published online: 3 April 2019‘Health effects of dietary risks in 195 countries, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017’DOI: https://doi.org/10.1016/S0140-6736(19)30041-8​Authors: GBD 2017 Diet Collaborators (full list available here​​) Source: https://www.foodnavigator.com/Article/2019/04/05/Beyond-fat-and-sugar-Diets-low-in-whole-grains-fruit-and-nuts-associated-with-1-in-5-deaths

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Gist of Yojana, October 2018

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Source: http://www.xaam.in/2018/11/gist-of-yojana-october-2018.html

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i ♥ mascarpone

тръгнах да правя крем с маскарпоне и уиски от syl, после хванах ключовата дума strachatela от salted lemons и ... накрая забърках импровизация;;

1/2 кг

маскарпоне 4 жълтъка 4 белтъка 30 гр захар мус от сини сливи шоколадови перли, филирани бадеми маскарпонето се разбива с миксер жълтъците се разбиват със захарта белтъците се разбиват на пяна и всичко се бърка

украсата е въпрос на въображение. аз обичам мус от сини сливи, затова избрах него, заедно с филирани бадеми и шоколадови перли. а да, и шоколадова бисквита като stylish attachment.

Source: http://byplay.blogspot.com/2010/08/i-mascarpone.html

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BioActor study: Evidence so far suggests citrus flavanones, metabolites benefit gastrointestinal function

The researchers, affiliated with Maastricht University in the Netherlands and Ghent University in Belgium, wanted to provide a detailed overview specifically of the intestinal metabolism of citrus flavonoids and their interaction with the gut microbiota composition.

“Following oral ingestion, citrus flavanones reach the distal part of the small intestine and the colon almost completely intact, where they interact with the microbiota,”​ they reported in their paper​​, published recently in the journal Nutrients.​

Important to keep in mind, however, was that most of the studies on the subject that have been published so far were in vitro ​(observations on a petri dish) or on animals.

“Therefore, more research focusing on bioavailability and on effects in human subjects may help to improve our understanding of the effects of citrus flavanones in the human gut,”​ they added.

The research was funded in part by BioActor BV, a Dutch functional ingredients manufacturer that makes a branded citrus extract called MicrobiomeX. Lead researcher Yala Stevens, affiliated with Maastricht University, is also head of clinical research at BioActor.

In the US, the ingredient is distributed by Seppic, a division of French chemicals giant Air Liquide.

Human clinical trial​

Among the few human clinical trials included in the systematic review was one done on MicrobiomeX. It was a 12-week randomized, parallel, double-blind, placebo-controlled study on 50 overweight but otherwise healthy participants.

“The results showed MicrobiomeX anti-inflammatory activity as a result of a cross-talk between the active citrus flavonoids and the gut microbiome composition,”​ according to a press release circulated by BioActor announcing results of the systematic review.

“Indeed, a significant increase in the butyrate proportion of total SCFA was measured, and an almost significant reduction in calprotectin levels are signs of the positive contribution of MicrobiomeX to a balanced microbiome and host gut health.”​

Worldwide, the MicrobiomeX ingredient can be found as a stand-alone ingredient in some finished products, or in combination with different probiotic strains.

Source: ​Nutrients​ Published online, doi:10.3390/nu11071464 The intestinal Fate of Citrus Flavanones and their Effects on Gastrointestinal Health​​ Authors: Yala Stevens, et al.

Source: https://www.nutraingredients-usa.com/Article/2019/07/18/BioActor-study-Evidence-so-far-suggests-citrus-flavanones-metabolites-benefit-gastrointestinal-function

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Canadian supplement maker AOR launches ‘retail-ready’ DNA test kit

The Canadian dietary supplement and nutrition company, which started ramping up efforts for distribution and brand awareness in the US around 18 months ago, announced the DNA test kit launch at the Natural Products Expo West show earlier this month.

The product is slated to be ready for consumers to purchase by May of this year, according to the company.

“MyBlueprint looks at 85 of the key gene variations that are associated with health conditions and disease,”​ Dr Traj Nibber, founder, CEO, and director of research at AOR​​, told NutraIngredients-USA at the show. “There are so many genes, one of the challenges is how do you associate which gene with what health condition. In other words, there is so much noise.”​

‘Retail-ready’ DNA Kits are booming​

To develop the testing kit, AOR, which has been around for 20 years, partnered with fellow Canadian company DNA Labs​​.

“Typically, most DNA test kits are designed for the physician,”​ Dr Nibber said.

“This is designed for the retailer or a physician or naturopath that can offer it to a consumer. The customer takes it [using] an easy cheek swab, sends it off themselves, then they get their results through an e-portal,”​ he added.

In 2013, around 330,000 Americans had their DNA tested. This number jumped to 12 million by 2017, according to a report by the MIT Technology Review​​.

Ancestry, as opposed to health care, makes up the bulk of DNA testing kit sales and positioning.

Companies are spending millions of dollars in advertising DNA kits. Data from Kantar Media, an advertising research firm, revealed that the two largest DNA testing companies, Ancestry.com and 23andMe, spent $32 million and $11.5 million respectively in advertising for the first three quarters of 2018.

This in turn has increased overall awareness around DNA test, and healthcare-positioned DNA testing companies are following suit. TeloYears and Helix, two health-focused DNA companies, are among the five biggest advertisers in the DNA test kit space, according to Kantar Media’s latest data.

Will more supplement companies launch at-home test kits?​

Results from an AOR MyBlueprint test will help inform consumers about recommended diets and what increased risks his or her genetic variants suggest, such as an increased risk of obesity or diabetes.

It can also provide information on exercise amd specific nutrient needs, which is how the DNA test kit finds a place within AOR’s portfolio of products.

While there are many start-ups that have launched at-home testing kits as their flagship product, like Baze​​ and InsightTracker​​, AOR is one of few supplement companies launching its own branded at-home test kits. Another more established supplement company to get into the at-home testing kit space is Thorne Research, which launched GutBio earlier this year​​ and a handful of tests, ranging from thyroid to heavy metal level tests​​, last year.

Dr Nibber characterized the current landscape of research regarding the link between nutrition and genetic variants as having made “significant steps forward towards personalized nutrition, which is the holy grail, but still in its infancy.”​

Source: https://www.nutraingredients-usa.com/Article/2019/03/20/Canadian-supplement-maker-AOR-launches-retail-ready-DNA-test-kit

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Las mejores pastillas y medicamentos para el dolor de muela

Elegir pastillas para el dolor de muelas debe hacerse con cuidado. Los analgésicos pueden ser un asunto delicado. Medicamentos como la hidrocodona (nombre comercial Vicodin) y la oxicodona (nombre comercial Percocet) son opioides peligrosos y altamente adictivos que las personas pueden utilizar para un dolor dental sin saber a lo que se exponen. Lo mejor es evitarlos y utilizar otros analgésicos de venta libre.

El peligro de uso de pastillas para el dolor de muelas de tipo opioide

Las muertes relacionadas con estos opioides han alcanzado niveles muy altos. Así lo reporta el Centro para el Control y Prevención de Enfermedades Estadounidense (Referencia).

A pesar de que este estudio revela que el aumento más grave de esas muertes está relacionado con drogas ilegales como la heroína, más de un tercio de esta estadística se asocia a opioides de venta con prescripción como el Oxycontin, el Percocet y el Vicodin.

También se demuestra qué la fuente más común para que la gente pueda obtener estos medicamentos es su dentista.

Más de la mitad de estos opioides son recetados por un médico a personas que tienen problemas con las muelas del juicio y les quedan pastillas después del tratamiento (Referencia).

El peligro con el mal uso de las pastillas para el dolor de muelas

Investigadores de la Universidad de Pensilvania estiman que recetar pastillas innecesariamente termina por añadir 100 millones de pastillas en los gabinetes de medicinas de los norteamericanos cada año.

El resultado de esto es un mal uso de estos medicamentos, que terminan siendo consumidos por los pacientes, amigos y su familia de forma perjudicial. De hecho se considera que una vasta mayoría de personas con problemas dentales hacen uso de medicamentos analgésicos sin prescripción. (Referencia)

Los dentistas deben reconocer que este problema de prescripciones innecesarias tiene un impacto importante en el incremento del abuso de los opioides.

Lee nuestra guía sobre el dolor de muelas: Causas, qué puede hacerse y cómo aliviar el dolor

¿Cuáles son los tipos de medicamentos analgésicos para quitar el dolor de muelas?

Existen dos tipos mayoritarios de analgésicos, diseñados para calmar los dolores: (Referencia) (Referencia)

Analgésicos a base de opioides.

Analgésicos sin opioides.

Los analgésicos con opioides

Los analgésicos con opioides suelen llamarse narcóticos. Uno de los más conocidos es la morfina y son producidos con opio. Son analgésicos muy poderosos que, al incrementar la dosis, aumenta el bienestar y contrarresta el dolor en gran medida.

Sin embargo, estos analgésicos son potencialmente peligrosos a causa de sus efectos secundarios, que aumentan entre mayor sea su consumo.

Estos analgésicos no son comunes en la práctica odontológica, pero pueden recetarse para tratar ciertos malestares, pero siempre por cortos períodos de tiempo para evitar efectos secundarios o su adicción.

Analgésicos sin opioides para quitar el dolor de muelas

Los analgésicos sin opioides se utilizan para tratar los dolores en los dientes. Suelen recetarse mientras se consigue el tratamiento apropiado para lidiar con condiciones odontológicas, antes y después de una operación.

Existe suficiente evidencia científica para aceptar que tomar una dosis de ibuprofeno antes de una operación odontológica, puede reducir de forma considerable el dolor que se produce después de la operación.

Esto se logra gracias al efecto del ibuprofeno para evitar la producción de sustancias que el cuerpo genera para inducir el dolor.

Los analgésicos cumplen su función, ya sea reduciendo la inflamación o disminuyendo la respuesta del cerebro frente al dolor, a través del sistema nervioso.

A veces, es bastante útil utilizar dos tipos de analgésicos para aumentar los efectos que contrarresten el dolor y mantener los efectos secundarios al mínimo.

Nuestra advertencia es que cumplas al pie de la letra las indicaciones de tu médico y, en el resto de los casos, las indicaciones señaladas en la caja del medicamento.

Existen fármacos que no pueden ser tomados por cualquiera, sobre todo si estás en algún tratamiento o si tienes alguna condición médica.

Lee nuestra guía sobre los 20 remedios caseros para aliviar el dolor de muelas

¿Cuáles son los tipos principales de analgésicos sin opioides?

Analgésicos salicílicos

En este grupo, la aspirina es el analgésico más conocido y usado con mayor frecuencia. Además de ayudar a reducir la inflamación, también contrarresta la fiebre.

Otra de sus propiedades tiene que ver con su efecto en la coagulación de la sangre. Al momento de extraer una muela es necesario reducir esa coagulación y la aspirina puede lograrlo.

Por esto, la aspirina no suele recomendarse para tratamientos postoperatorios, ya que en estos casos se busca generar el efecto contrario para una recuperación más rápida.

Analgésicos antiinflamatorios no esteroideos (NSAID por sus siglas en inglés)

Este grupo de analgésicos son similares a la aspirina en su forma de actuar, sus efectos farmacológicos y reacciones secundarias.

Estos analgésicos tienen un efecto poderoso para aliviar el dolor, al tiempo que actúan de forma antiinflamatoria en el organismo.

Son mucho más seguros que los opioides y pueden utilizarse para controlar dolores que van de bajo a moderado, lo que los convierte en los más efectivos para problemas dentales.

Los analgésicos antiinflamatorios sin esteroides se encuentran en un rango de acción que varía según su intensidad.

La dosis más alta que se puede tomar de ibuprofeno es de 400-800 miligramos. Una dosis mayor deja de tener beneficios en cuanto al alivio del dolor de los dientes.

Generalmente, un dentista solo recetaría dosis más altas si hay hinchazón.

Al igual que su efecto para aliviar el dolor, su acción antiinflamatoria también es importante.

El ibuprofeno suele usarse en un tratamiento combinado con el paracetamol para aliviar los dolores de muela, o incluso dolores bastante severos, añadiendo un efecto antiinflamatorio mayor.

Debido a que el paracetamol funciona de manera diferente, puede combinarse con analgésicos sin esteroides como el ibuprofeno.

El ibuprofeno generalmente suele ser bien tolerado y, en algunos casos, llega a producir malestar gastrointestinal. (Referencia)

El ibuprofeno puede contrarrestar el efecto anticoagulante de la aspirina, por lo tanto, aquellos que toman aspirinas como tratamiento cardiovascular deberían evitarlo.

Otro analgésico antiinflamatorio sin esteroides es el diclofenaco, al igual que el aceclofenaco, los cuales pueden causar menos efectos gastrointestinales.

Acetaminofen o paracetamol para quitar el dolor de muleas

El acetaminofen o paracetamol actúa de forma más central y se enfoca en bloquear las señales de dolor que recibe el celebro. Tiene poco efecto en reducir la inflamación, pero es un medicamento altamente efectivo para tratar el dolor de muelas. (Referencia)

Es bastante útil para quienes no pueden tomar aspirinas y puede combinarse con analgésicos antiinflamatorios sin esteroides para amplificar sus efectos.

Una dosis de 400-500 miligramos suele utilizarse comúnmente, aunque la mayor dosis efectiva para tratar un dolor de muelas es de alrededor de 1000 miligramos.

El uso excesivo del acetaminofen puede causar potencialmente daños en el hígado, lo cual debe tomarse en cuenta, especialmente cuando se combina con dos o tres analgésicos. El uso de terapia combinada de analgésicos también se ha propuesto en algunos casos (Referencia)

Solo cuando la dosis de analgésicos antiinflamatorios sin esteroides o paracetamol está en su nivel más óptimo y sigue sin ser efectivo, se vuelve necesario un analgésico a base de opio.

Pero esto suele ser raro en la mayoría de los casos de problemas odontológicos.

Lee nuestra guía sobre le paracetamol: Para qué sirve, efectos secundarios, usos y dosis

Conclusión

El dolor en los dientes puede hacerte sentir miserable y debilitarte de forma considerable. Puede hacer qué comer o dormir se vuelvan tareas complicadas, por lo tanto, el alivio del dolor se convierte en algo esencial.

No siempre es posible conseguir tratamiento médico inmediato, así que debemos sentirnos afortunados de tener medicamentos efectivos y extremadamente útiles para controlar estas situaciones y hacerlas llevaderas.

Los analgésicos son altamente necesarios para controlar el dolor en los dientes, luego de un procedimiento quirúrgico odontológico.

La clave para manejar exitosamente un dolor de muelas es diagnosticar correctamente la causa y aplicar el tratamiento apropiado, junto con medicamentos para aliviar el dolor mientras sea necesario.

En general, los analgésicos antiinflamatorios sin esteroides y el paracetamol pueden controlar el dolor de muelas con muy pocos o ningún efecto secundario, siempre que se cumplan las dosis recomendadas. (Referencia)

¿Qué medicamento es para el dolor de muelas?

El medicamento para el dolor de muela ideal es aquel que tenga una potencia suficiente como para producir un alivio rápido y a su vez, no tenga mayores efectos secundarios. De esta manera se pude control ese síntoma tan desagradable hasta que se puede hacer una consulta con sus dentista de confianza

Pero, qué tomar para dolor de muela, lo ideal es tomar un analgésico no opioide, como los antiinflamatorios no esteroideos, como ibuprofeno o ketorolaco. Hay que tomar en cuenta, que es importante conocer los antecedentes de alergias a medicamentos y enfermedades que puedan ser una contraindicación para determinados analgésicos

UN antiinflamatorio no esteroideo sirve también como medicamento para el dolor de encías o gingivitis. En estos casos hay también pastillas para desinflamar las encías, de uso tópico o masticables.

¿Cuál es el mejor analgésico para el dolor de muelas?

El mejor medicamento para dolor de muela y también el mejor medicamento para inflamación de encías, son los antiinflamatorios no esteroideos. Es siempre recomendable iniciar con analgésicos simples como el acetaminofen y luego avanzar a ibuprofen, diclofenac o ketoprofeno. Los opioides se reservan para casos muy severos o tratamientos postoperatorios, siempre bajo prescripción médica.

¿Cuántas pastillas de ketorolaco de 10 mg puedo tomar?

El ketorolaco forma parte de las pastillas para el dolor de muela, gracias a su efecto analgésico rápido y potente. También hay presentaciones de absorción rápido en la mucosa oral que permiten un efecto analgésico aun más rápido.

La dosis máxima de ketorolaco al día es de 120 mg, que se pueden repartir en 30 mg cada 6 horas. Sin embrago, la mayoría de la personas, suelen mejorar con 10 mg o máximo 20 mg en cada dosis. Inicie con dosis bajas y puede incrementar la dosis de acuerdo a la respuesta.

Para un dolor de muela analgésico debe ser administrado de acuerdo a la  necesidad de cada persona.

¿Qué se puede tomar para el dolor de muela estando embarazada?

El embarazo condiciona toda una serie de cambios que pueden afectar la salud oral. Es importante acentuar las medidas de higiene oral para evitar problemas odontológicos.

Si estás embarazada siempre la hay dudas acerca de que que puedo tomar para dolor de muela, que no afecte al feto.

En el caso de los analgésicos más seguros está el acetaminofen y el ibuprofen, que se consideran categoría B en el embarazo, según la FDA. (Referencia)

¿Qué pastillas son buenas para el dolor de muelas?

Un buen medicamento para dolor de muela y desinflamar es el ibuprofeno y otros medicamentos antiinflamatorios como el ketoprofeno, ketorolac o diclofenac.

¿Qué es bueno para el dolor de muelas?

La mejor forma como calmar el dolor de muela, mantener una higiene bucal adecuada, usar analgésicos de venta libre como el acetaminofen o el ibuprofen, en forma temporal hasta la visita al odontólogo.

Se puede aplicar una compres fría en la parte exterior de la mejilla en forma intermitente.

¿Qué es mejor para el dolor de muelas paracetamol o ibuprofeno?

Entre las pastillas para el dolor de muelas se encuentran toda una serie de analgésicos y antiinflamatorios que tienen una potencia variable de acción. En general, el ibuprofen tienen un efecto analgésico y antiinflamatorio mayor que el acetaminofen, puede ser una elección adecuada en la mayoría de los casos.

Sin embrago, en personas con problemas gástricos, es mejor usar el acetaminofen.

¿Cómo calmar el dolor de las muelas del juicio?

Las pastillas para el dolor de muela del juicio son las mismas que para otro tipo de dolor de origen dental. El dolor de las muelas del juicio suele ser moderado a fuerte intensidad, por ello sería conveniente elegir un medicamento potente como el diclofenaco o el ketorolaco.

¿Qué pasa si tomo 30 mg de ketorolaco?

En caso de que se necesite que tomar para el dolor de muela intenso, es mejor iniciar con medicamentos como el ketorolaco, que tiene una acción potente y a su vez rápida. No aconsejamos usar drogas como los opiáceos, que suelen ser efectivos pero se deben comprar con receta médica y tienen otros efectos indeseables.

¿Qué es bueno para el dolor de muelas remedios caseros?

Si quieres evitar tomar pastillas para dolor de dientes, hay opciones más tradicionales y naturales sin necesidad de medicamentos. Vale la pena probar y apreciar su eficacia.

Enjuagues de agua con sal

Enjuagues con agua oxigenada, y luego refrescar con enjuagues de agua fresca

Morder ajo que tiene  efecto antiinflamatorio.

Extracto de vainilla en gotas y aplicar sobre el área del dolor

¿Qué hacer para el dolor de muela en casa?

como aliviar el dolor de muela

¿Cómo calmar el nervio de una muela?

El producido de muela puede estar originado por las encías, por procesos inflamatorios o también por afección del nervio que se encuentra en la pulpa de los dientes. Este sitio es particularmente molesto cuando está inflamado.

Saber qué medicamento sirve para el dolor de muela cuando está afectado el nervio siempre es una solución temporal y parcial. Los medicamentos que tienen acción a este nivel son los opiáceos y el ketorolaco a dosis mayor de 20 y 30 mg.

Lo importante del dolor de muelas por afección del nervio es acudir lo más pronto posible al odontólogo para resolver el origen ya que puede traer consecuencias mayores.

Pastillas para dolor de muela picada

Una pastilla que se puede tomar para el dolor de muela picada, es el acetaminofen, la dosis regular es entre 500 y 650 mg. por dosis. También puede usarse el ibuprofen con una dosis de 400 hasta 800 mg por dosis.

Estos tratamientos son provisionales hasta la consulta con el odontólogo.

¿Cuáles son los medicamentos para dolor de muela y desinflamar?

Los medicamentos ideales para el dolor de muelas y desinflamar son los antiinflamatorios no esteroideos. Estos medicamentos son ibuprofeno, diclofenaco sódico y potásico, ketoprofeno y ketorolac, entre otros.

Tienen efecto antiinflamatorio y analgésico. Sin embrago, su uso debe ser limitado por efectos vasculares, renales y gastrointestinales, además la mejoría del dolor e inflamación de origen dental se resuelve con el tratamiento del origen que lo realiza el odontólogo.

Pastillas para el dolor de muela del juicio

El medicamento para dolor de muela del juicio, puede ser cualquier tipo de analgésico de venta libre, desde acetaminofen hasta antiinflamatorios no esteroideos como ibuprofeno, diclofenaco y el ketorolaco. No se recomienda el uso de aspirina ni de opiáceos como el tramadol.

Antibiótico para el dolor de muela

Hay tipos de antibióticos para dolor de muelas, los más usados son la amoxicilina, ampicilina y amoxicilina con ácido clavulánico. Cualquiera de estas opciones u otras deben ser indicadas por el odontólogo en caso que sea estrictamente necesario.

¿Qué tomar para el dolor de muela muy fuerte?

Hay varias opciones qué tomar para el dolor de muela fuerte. Una posibilidad es el tramadol o medicamentos opiáceos que no los aconsejamos como primera opción, por sus efectos indeseables y además necesitan receta médica.

Mejor alternativa representan los antiinflamatorios no esteroideos, entre los cuales el ketorolaco tiene una acción muy rápida y potente. Las dosis no deben exceder los 30 mg.

¿Qué hacer con el dolor de muelas insoportable?

Un medicamento fuerte para el dolor de muela insoportable, es el ketorolaco de 30 mg o el ketoprofemo de 100 mg. Son medicamentos de acción rápido y efectiva.

Insistimos que aconsejamos la pronta visita al odontólogo que resuelve el origen del problema sin necesidad de prolongar el uso excesivo de analgésicos que tienen sus efectos secundarios.

¿Qué es bueno para el dolor de muela fuerte?

La mejor forma cómo calmar el dolor de muela es acudir lo más pronto posible al odontólogo y resolver el origen del dolor. Mientras tanto, se puede usar antiinflamatorios no esteroideos, como el ibuprofeno 600 mg por dosis o el ketorolaco 10 mg por dosis.

Antibiótico para el dolor de muela

La medicina para el dolor de muelas está condicionada al origen del dolor, en ocasiones es necesario usar antibióticos, entre lso que se eligen la amoxicilina 500 mg cada 8 horas o bien amoxicilina con ácido clavulánico 850 mg cada 12 horas.

La visita al odontólogo no se debe postergar, y por tanto, lo mejor sería esperar la indicación del dentista y no automedicarse.

Antibiótico para infección de muelas amoxicilina

En la visita al odontólogo se podrá determinar exactamente el origen del dolor de muelas. El remedio del doctor para el dolor de muelas va a depender  si hay o no alguna infección de mayor consideración que amerite antibióticos. Si los pacientes no son alérgicos a la penicilina, el uso de la amoxicilina está muy difundido para las infección de la cavidad oral. La amoxicilina puede tomarse sola o en combinación con el ácido clavulánico.

Remedios científicos para el dolor de muelas

Un remedio científico para el dolor de muelas es un antiinflamatorio que cumpla un función analgésica y que no interfiere en posibles tratamientos posteriores que necesite realizar el odontólogo. En ocasiones se necesitan antibióticos que se eligen de acuerdo a cada caso.

Hay varias alternativas de pastillas para el dolor de muelas que puedes usar antes de ir al odontólogo.

Ver también:

Referencias

Brandon C. Maughan, Elliot V. Hersh, Frances S. Shofer, Kathryn J. Wanner, Elizabeth Archer, Lee R. Carrasco, Karin V. Rhodes. Unused opioid analgesics and drug disposal following outpatient dental surgery: A randomized controlled trial. Drug and Alcohol Dependence 2016. 168:328-334. Disponible en: https://doi.org/10.1016/j.drugalcdep.2016.08.016.

Centers for Diseases Control and Prevention. Increased in drug and opioid involved overdose deaths. United States 2010-2015. Disponible en: https://www.cdc.gov/mmwr/volumes/65/wr/mm655051e1.htm.

Hargreaves K y Abbott PV. Drugs for pain management in dentistry. Aust Dent J. 2005 Dec;50(4 Suppl 2):S14-22. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/16416713.

Heard, K. J., Ries, N. L., Dart, R. C., Bogdan, G. M., Zallen, R. D., & Daly, F. (2008). Overuse of non-prescription analgesics by dental clinic patients. BMC oral health, 8, 33. Disponible en: https://doi.org10.1186/1472-6831-8-33.

Moeller, J., Farmer, J., & Quiñonez, C.  Patterns of analgesic use to relieve tooth pain among residents in British Columbia, Canada. PloS one. 2017, 12(5), e0176125. Disponible en: https://doi.org10.1371/journal.pone.0176125.

Mehlisch DR. The efficacy of combination analgesic therapy in relieving dental pain. J Am Dent Assoc. 2002 Jul;133(7):861-71. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/12148679.

Pozzi, A., & Gallelli, L.  Pain management for dentists: the role of ibuprofen. Annali di stomatologia. 2012, 2(3-4 Suppl), 3–24. Disponible en: h https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414241/.

Deshpande, A., Bhargava, D., & Gupta, M. (2014). Analgesic efficacy of acetaminophen for controlling postextraction dental pain. Annals of maxillofacial surgery, 4(2), 176–177. Disponible en: https://doi.org10.4103/2231-0746.147117.

Becker, D. E., & Phero, J. C. (2005). Drug therapy in dental practice: nonopioid and opioid analgesics. Anesthesia progress, 52(4), 140–149. Disponible en: https://doi.org10.2344/0003-3006(2005)52[140:DTD]2.0.CO;2.

Vt, H., T, M., T, S., Nisha V, A., & A, A. (2013). Dental considerations in pregnancy-a critical review on the oral care. Journal of clinical and diagnostic research : JCDR, 7(5), 948–953. Disponible en: https://doi.org10.7860/JCDR/2013/5405.2986.

Source: https://laguiadelasvitaminas.com/pastillas-para-dolor-de-muela/

[bushstory61-blog]

The Eatwell Guide

Sheila Dillon questions whether the government's Eatwell Plate that's issued to the medical profession and used as public guidance for a balanced diet could actually be harming us. An increasing number of medics are abandoning the plate because they say it still promotes dangerously high levels of starchy carbohydrates and processed foods that contain high levels of the sugars that cause many of today's chronic diseases such as obesity, diabetes and heart disease. Cardiologist Dr Aseem Malhotra author of the Pioppi diet is campaigning to change the official advice and says that a healthy diet and lifestyle are the key to reducing disease and the need for medication, but he says that vested interests from the food and pharmaceutical industries make some of these healthier choices more difficult to achieve. Dr David Unwin is a GP who has seen a huge spike in patients presenting with Type 2 Diabetes since he began practicing forty years ago. He advises lifestyle changes that include abandoning the Eatwell Guide and cutting out the starchy carbohydrates, processed foods and sugars and has seen a reversal of the disease in a significant number of patients. Sheila also visits Tameside Hospital in Greater Manchester which is overhauling its canteen food and vending machine produce to reduce processed carbohydrates and sugary drinks and snacks. In celebration of the 70th anniversary of the NHS the hospital will go completely sugar free on July 4th. Is it time to revise the Eatwell Guide and what will it take to do so?

Producer: Maggie Ayre.

Source: https://www.bbc.co.uk/programmes/b0b86702

[bushstory61-blog]

This Is the Best Time of Day to Take Vitamin C - Reader's Digest

irishe4kaaa/ShutterstockVitamin C is an antioxidant powerhouse that may help shorten the duration of common colds and improve healing after surgery and that’s not all—checkout 13 more potential health benefits of vitamin C. But to get the most from your supplements, you have to take C at the right time of day.

Also known as L-ascorbic acid, vitamin C is a water-soluble vitamin. This means it is easily absorbed into body tissue. Unlike fat-soluble vitamins, water-soluble vitamins can’t be stored by your body, so you need to replenish vitamin C regularly by eating C-rich foods or by taking supplements. Excess C and other water-soluble vitamins are cleared from your blood by your kidneys and excreted in your urine.

The National Institutes of Health experts recommend that men get 90 milligrams of vitamin C a day; women should aim for 75 milligrams. If you smoke, add 35 mg to those values. Smoking can deplete vitamin C; these are the signs you may be deficient in vitamin C.

So what’s the best time of day to take your vitamin C supplements? That’s simple, says Robert Zembroski, DC, MS, a functional medicine specialist in Darien, CT, and the author of several books including Rebuild: Five Proven Steps to Move from Diagnosis to Recovery and Be Healthier Than Before: Aim to take it at the same time every day, he says—but take it after a meal. Vitamin C is highly acidic so it may cause nausea when taken on an empty stomach. Some experts suggest pairing it with a meal to stave off nausea.

Another option is to split up your doses, says Zembroski: This can improve absorption, reduce the chance that it will make you nauseated, and it can help keep your blood levels high all day as you won’t be excreting as much of it in urine. Scheduling your dose after the same meal (or meals) each day will help you remember to take it, he says.

If you are thinking about taking C supplements, Zembroski suggests a powdered form of vitamin C called NutraMetrix Isotonix® Vitamin C or Ultra Potent-C. Before you take the first dose, read up on ways to make vitamins more effective.

Source: https://www.rd.com/health/wellness/vitamin-c-time-day/

[bushstory61-blog]

Vitamin K2 Status May Impact Blood Pressure and Pulse Wave Velocity

The American Heart Association has published a new study examining the effect excessive inactive Matrix Gla Protein (MGP) has on cardiovascular health, namely increased stiffening and calcification of large arteries. This stiffening increases cardiovascular stress, which can be accurately assessed using pulse wave velocity measurements, and can be alleviated by improving one’s vitamin K2 status. 

The study, “Central Hemodynamics in Relation to Circulating Desphospho-Uncarboxylated Matrix Gla Protein: A Population Study”, evaluated vitamin K status (dp-ucMGP) in 835 randomly recruited Flemish individuals. The researchers found that higher inactive dp-ucMGP was associated with greater pulse wave velocity (PWV), central pressure, forward pulse wave, and backward pulse wave.

The authors wrote: “Stiffening and calcification of the large arteries are forerunners of cardiovascular complications. MGP, which requires vitamin K–dependent activation, is a potent locally acting inhibitor of arterial calcification. We hypothesized that the central hemodynamic properties might be associated with inactive desphosphouncarboxylated MGP (dp-ucMGP).”

The authors concluded that, along with the current body of literature, the study’s findings show “In people representative for the general population, higher inactive dp-ucMGP was associated with greater PWV, central pulse pressure, forward pulse wave, and backward pulse wave. These observations highlight new avenues for preserving vascular integrity and preventing cardiovascular complications (eg, by improving a person’s vitamin K status)."

The paper is significant because it articulates the importance of pulse wave velocity measurements in gauging cardiovascular impact, and adds to the significant body of evidence NattoPharma has cultivated showing that improving K status can provide true health benefits, according to NattoPharma Chief Medical Officer Dr. Hogne Vik. 

“This research again confirms a link to vitamin K status and risk of cardiovascular health. NattoPharma's research has shown that vitamin K2 supplementation can halt and even regress progression of arterial stiffness. This paper recognizes that stiffening and calcification of the large arteries are forerunners of cardiovascular complication, and the mechanism to prevent this is the vitamin K-dependent activation of MGP.”

“Importantly,” Vik continued, “only vitamin K2 intake has been linked to cardiovascular benefit as K2 is the most bioactive and longest-lasting form of vitamin K. Vitamin K1, for example, has not been linked to cardiovascular benefit as K2 seems to be the form of K active outside of the liver for cardiovascular health.”

Source: https://www.nutraceuticalsworld.com/contents/view_breaking-news/2019-05-02/vitamin-k2-status-may-impact-blood-pressure-and-pulse-wave-velocity/

[bushstory61-blog]

SPOTTED ON SHELVES – 10/3/2018

Here are some interesting new and limited edition products found on store shelves by your fellow readers. If you’ve tried any of the products, share your thoughts about them in the comments.

(Spotted by Sarah R at Whole Foods.)

(Spotted by Robbie at H-E-B.)

(Spotted by John R at Walmart.)

(Spotted by Robbie at H-E-B.)

(Spotted by Robbie at H-E-B.)

(Spotted by Deborah S at H-E-B.)

If you’re out shopping and see an interesting new product on the shelf, snap a picture of it, and send us an email (theimpulsivebuy@gmail.com) with where you found it and “Spotted” in the subject line. Or reply to us (@theimpulsivebuy) on Twitter with the photo, where you spotted it, and the hashtag #spotted. If you’ve tried the product, share your thoughts about it in the comments.

Also, if you want to send in photos and are wondering if we’ve already covered something, don’t worry about it. Let us worry about it.

Here are a few posts that might interest you:

Source: https://www.theimpulsivebuy.com/wordpress/2018/10/03/spotted-on-shelves-10-3-2018/

[bushstory61-blog]

Dr. Coimbra interview covering Vitamin D, Magnesium, Folate, Vaccines - Oct 2018

YouTube in Portuguese

23 minute interview in Portuguese

A few Dr. Coimbra items on VitaminDWiki

Translation by Google to English today I again called Professor cícero coimbra because're again that he was with us and brought a given so interesting that we ask for it back and tell all to you the teacher reminds thank you for your generous availability tac us our listeners more health of the whole Brazil and beyond Brazil taking advantage of already sending hi to our our Portuguese brothers we watch also not only what's going on that today we are with so much infertility but after this woman can get pregnant as she could be helping that baby since the middle bb environment is she optimize improve throughout not only the cognitive part but emotionally also that child first gratitude is all my guarantees to make sure I am very grateful for the opportunity you offer to bring this information public it should feel that way too so it are many factors not are many factors but I think there are factors is that are critical we could mention one by one from among these criticisms in a way summed up to a critical point i am are the two major shortcomings of the world's population and mostly or accidental vitamin D deficiency is a something very important people today are not exposed to the sun they live and work in environments confined not supplementation with vitamin d the fact that vitamin d have that name wrong vitamin is because it is much more than a hormone people find you will find vitamin d in food that has a balanced diet but did not finish the amount which has the food should end and whimsy the result is because of the change of the population habits is not because the vitamin D produced in the leg when you expose one individual habits postponing changes fast the population that have occurred in recent decades but generation malls in people abandoned parks start using sunscreen listening to a adding to plenty of fun in between four walls in confined environments such as the internet and videogame is and similar to today we have nine out of ten people on disability with planet vitamin D that is made worse by its own factors of diet that people gradually acquired able to diet wrong that people gradually acquired along these same decades in reducing the consumption of greens leaves raw green that has a reason folate that vitamin b9 natural as important to maintain the altered genes that all we have silent and bb own in that when forming in the womb mother he received the genes both changed both the father and the mother and he needs natural vitamin b9 to increase folate to keep silent these altered genes in such a way that it does not develop a training with birth defects and has the development of optimized brain so it's important that we talk numbers I think it's something objective is not mine and I have insisted and will avail new this opportunity you me always offers all the other should take 10,000 units of vitamin d per day this is far from a dose toxic is recognized by all researchers of this vitamin area d as a a free dose effects toxic since that the person has at least 50 kilos there is no problem in taking 10,000 units of vitamin D per day and we could not because of the habits of modern urban modern life to get this through sun exposure is virtually impossible right because the only natural source of vitamin D in the skin exposure to the sun the aam then 10 000 units per day is half the maximum you produce for a few minutes of sun exposure so it is very important that we say that imagine a person who has fair skin who is young has fur young is lying in the pool under the sun strong right with almost all your body exposed to the sun is able to produce 20 to 25 thousand units of vitamin d then no one will ever be intoxicated with vitamin d by sun exposure are 10,000 units of vitamin d is half the maximum you produce in ten minutes of sun exposure this way without using sunscreen then and we have observed that mothers who take 10,000 units of vitamin d during pregnancy them on rules give birth to babies who shows the psychomotor development out of the ordinary are actually children I am very hesitant to use this expression but in this case I have no doubt they are gifted children we agree We have beautiful experiences in the office just as well because as a dose that nutritionist can not pass so thank God I have doctors who can sustain that this dosage and have seen people things very interesting that we then is exchanging experiences is fabulous a child gestated in the middle atmosphere where the mother is 10,000 units International daily of vitamin d is another child you even one day can suddenly do not you can not really do all that we want but it was very interesting you can see the difference but still the teacher has a lot to talk it is important you dream is not true then you might think if you're you need magnesium to activate vitamin D for you do not ingest or produce the skin vitamin D on the inactive form then the population in the western population we have 80% of disabled population magnesium because the foods that are consumed are foods that is that foods are rich in magnesium are not consumed came imagines hissing if you want to have a baby with brain development to optimized that will actually take will show whether a child It has a potential emotional cognitive instability emotional unusual that surprises the parents you have to give mainly vitamin D magnesium proper doses you have to give up these habits such as in managing soft glue that dramatically damaged the absorption of magnesium you have to have vegetables in their food vegetables raw in bringing methyl folate and vegetables in general already bring a sliver crowns or no longer bring magnesium but you can implement magnesia you can implement magnesium you can further folate vitamin b9 natural you can take the 10 000 vitamin d units you should not should not take acid folic during pregnancy not to harm including the development of the child brain and overall health ah and prevent this child has to express genes that cause the sam that cause diseases that cause congenital malformations so if we could dream so with a with that all pregnant women and follow that this view is exactly you imagine what would happen 20 years from now with this country will be wonderful but you are here to attend teacher who left thank god we will be here we will see a wonderful generation coming up you are having A paper fantastic in promoting that this birth of these perez and people that just can because this vehicle communication network new song 've talked to you if I can bring people like Professor cícero with an international genius is because here we can talk about all that our commitment is to the truth and the truth will set you free teacher what else I say today that we will change now the next generation good think it's important we talk about this big problem on autism explosion will not have to and all these guidelines we mentioned in the administration sacked folate and not folic acid administration of 10,000 units during pregnancy effectively prevents the emergence of born the birth of autistic children today there are very clear data demonstrating that autism optimism is an autoimmune disease Community industry it can be even treated with vitamin d in when we settled I think one thing a true crime is not we let so many people with vitamin deficiency to vaccinate these children because I am not against the vaccine only for the vaccine but vaccinate a population that disability and efficient and vitamin d that is so important vitamin D based mental for you and your immune system work in your favor and not against you in so you have a low level of vitamin D allows you to trigger the immune system for example through another time vaccination until a opposition denies one there such a virus situation and bacteria in an infection I wanted to tell you trigger the system immune deregulated by a lack of vitamin immune system to can attack your own body and often you notice that sometimes days after a vaccination the child changes his behavior and months later is characterized as having an autistic behavior is against non vaccine is to vaccinate without the protection of vitamin D speaking children it takes we will leave this mother a given what the vitamin D dose for children for example is calculated per kilogram of weight right we a generally have suggested that children at birth right is not being breastfed by mothers taking adequate doses of vitamin d that are miguel 10min that chicken during the entire period of breastfeeding which has to be kept exactly but if the child child must receive it is not the case and even if it would that is being nursed by the mother who takes 10,000 units no problem no she said birth already receive thousand units are independent of the weight that it has a tinge thousand by 15 thousand international units per day and from then when it reaches 10 kilos of weight it starts to take two thousand units 15 000 3000 units ie five kilos more adds another thousand units we go for a quick break and we came back because today Dr. coimbra will give us the recipe to have a generation here 20 years wonderful program and wait for more health today marking history for all this new generation what we can do to improve health behavior cognition finally change this generation that I am well even said that they are having another problem in school learning right now is but the endocrinology society that Brazil launched a documentation and reported that 20 kg per deciliter of vitamin blood d is already considered good this is half the minimum which is a dock on its website that the technology company north American recommended as the minimum then again pregnant woman what she needs to do 10,000 units vitamin d have to take a day magnesium magnesium supplementation least 800 milligrams have to take care of this issue 800 milligrams to for example 500 milligrams of magnesium chloride has only 60 milligrams of magnesium is then so must be if a magnesium already capsule has to look have to note this is not only a magnesium chloride recipe on the radio for us is how chloride magnesium have and have sachets of 33 grams available in any ordinary drugstore dirt - cheap $ 10 for seven days of treatment you put a known content a sachet one liter of water and 50ml you take four times a day is a day to be an American cup or so but will decide it at the time - it's a little bit I want it but it's her he must take before an hour before the power not to cause diarrhea is due to reduce the dose we have recommended that one take the highest dose of magnesium can do that it will include every day always with the gut every day without having diarrhea that is not there you that this is what has been recommended to the literature because the use of laboratory tests magnesium do not reflect their need anne so no use looking exams lab on the issue of vitamin D if you take 10 to 10 thousand units per day people of lower weight as we have 50 fifty-odd kilos may even spend a little of what the laboratory considers as normal so in grams per ml but see search the fishermen have 160 9 grams per ml called up here is a natural question is not is not really toxic dose just above 100 not grams per ml but if we really say that 20 on the long but a little more than twenty- nine grams per ml is the correct dose is a full right concentration better off than if they touch by tax 30 is for people in risk groups is the love of God people with the risk group is totally another story right teacher come is that part emotional as we may be showing to the people especially for these next mothers are carriers of these super bbc the future what they need to take care of is the emotional is critical not have experiments that are even made with mice in which you submit both rats males and females to stress using the noise that the biggest most stressor mice for rats and after subjecting them to a period where a high noise level you put these animals to mate and you see that the offspring is born with several various malformations congenital conclusion is the father of stress is the mother's stress that you alter the genetics of shirts of performances brothers and egg and bringing those that child then not having to silence their altered genes because stress takes but from what we could say it's just so the public could understand right we have the ability if we have methyl folate natural vitamin b9 and is not the acid folic not acid folic our body has the ability to place as were tape strips in the mouth of nice they are changed so that they do not express causing things like congenital malformations to the same thing happens during pregnancy if you have a couple who are in discussions frequently keeping with the mother maintaining a high level of stress you unfairly prejudice the system and genetic silencing of genes altered the bbi and bb so much need of gene silencing right and you would change the development of the baby brain development you predict we saw early in pregnancy you will cause congenital malformations by pure emotional stress so the mother needs peace she needs a balanced emotional throughout pregnancy to give the allus is a healthy child emotionally balanced with great optimized brain development is not beyond all factors with vitamin d magnesium issue folate we need an emotional well balanced during pregnancy and today as everybody's stressed think today is the enemy is a number all because they do not have a disease autoimmune I take the office that I will make an assessment it does not It has so aroused after stress yes that was published in more than six thousand scientific life events articles and stressful precede the appearance the autoimmune disease outbreaks including multiple sclerosis is then that in fact is one thing an already critical factor it affects their genetic it affects behavior of your immune system it favors the emergence of diseases italy autoimmune is this going black with a pregnant woman who is going through all this stress thousand situations but whether it is making use of issue folate melt finally mine magnesium it can help this baby to start some young people by stress the undoubtedly heavy inclusive is important to remember that it is magnesium is a factor of let's say a very important emotional stabilization is that magnesium reticence and produces depression and hyper real activity emotional about the problems that you face cognitive impairment that leads you have difficult to take forward decisions to stressful situations so I can even say it by experience itself doses such that we recommended magnesium 800 milligrams of magnesium daily food fractionated into four doses giving to you one tranquility in coping their big problems I'm wrong when I say so nutrient of intelligence our emotions without doubt if completely why I love this footprint program teacher process here to steal Professor Coimbra several times more health by radio that we are close to where he's he promised he will get time for us please and last considerations there his deeply the opportunity is here .........................

Source: https://vitamindwiki.com/tiki-index.php?page=Dr.+Coimbra+interview+covering+Vitamin+D%2C+Magnesium%2C+Folate%2C+Vaccines+-+Oct+2018

[bushstory61-blog]

Dr Nadia Pateguana & Dr Jason Fung – Polycystic Ovary Syndrome

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Dr Nadia Pateguana and Dr Jason Fung look at PCOS and argue that it is an endocrine and metabolic disorder closely tied to insulin resistance.

Presentation slides are available here to download in PDF format

Dr. Nadia Pateguana was born in Mozambique, but raised in Canada, where she completed her studies. She graduated from The Canadian College of Naturopathic Medicine in 2004 and also has a Degree in Honours Biology from McMaster University.

Dr. Pateguana returned to her home country for a few years where she ran a multidisciplinary clinic as the Medical Director and Naturopathic Doctor. She currently, and proudly, works as a Dietary Educator with Dr. Jason Fung and Megan Ramos at the Intensive Dietary Management Program. Her special focus is on helping women with PCOS overcome infertility through dietary modifications.

Dr. Jason Fung completed medical school and internal medicine at the University of Toronto before finishing his nephrology fellowship at the University of California, Los Angeles at the Cedars-Sinai hospital.

He now has a practice in Ontario, Canada where he uses his Intensive Dietary Management program to help all sorts of patients, but especially those suffering from the two big epidemics of modern times: obesity and type 2 diabetes.

Dr. Fung uses innovative solutions to these problems, realising that conventional treatments are not that effective in helping people.

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Source: https://denversdietdoctor.com/dr-nadia-pateguana-dr-jason-fung-polycystic-ovary-syndrome/

[bushstory61-blog]

Tackling inequity in education

The educational inequity in our country has hindered the right of education for all. The multi-fold socio-political and economic problems encumber the growth of the nation by keeping education missing from its seekers.

In order to challenge this inequity, Avanti Fellows, an NGO founded by the alumini of IIT Bombay, has been working on improving access to premium STEM college courses for the under-served, by addressing the systemic bias which exists against low-income students. They select the concerned students from Narvodhya Public Schools and provide free tuition for NEET and IIT-JEE examinations in order to make them at par with the competition.

Grassroot solution

“The rural students are unable to aspire to pursue a career in medical, engineering, or even commerce. As one not only has to be exceptionally smart but also fortunate enough to come from a strong economic background,” said Avanti Fellows’ Director, Deepak Kamble.

“There is a seven times lesser chance of a rural student making it to a good institution as compared to his urban counterpart due the lack of facilities. The vast gap between the education offered at private schools and the public schools deplete the chances of a bright student making it to the top notch colleges as they stand nowhere near the expected markers of qualification,” he adds.

According to him, the need of the hour is to work at the grassroot level and raise the quality of schooling in order to prepare students to fight the inequity of the educational system. “This is the beginning of a long battle, as the chances are very less that these students would be able to pay the tuition fees as even the most premium colleges of the country are unaffordable for many.”

Another initiative to bridge educational inequity is taken up by Prabudh, a PH.D student in sociology who gives free coaching classes for NET in Delhi. According to him, the commercialisation of education is hindering the right to education of students.

“The ‘eligibility’ paper of NET has become a tough competitive exam. In order to get into the academic system of the country, one has to splurge thousands on private coaching centres for learning the basic skills and qualify this arbitrary examination. The ones who are able to spend lump sums are at an advantage as compared to the ones who cannot,” he said. “The intervention of the government to formulate effective policies becomes important. However, these initiatives are only gaining momentum, the inequity in education system is yet far-fetched and hence needs to be raised and challenged.”

Source: https://www.thehindu.com/education/tackling-inequity-in-education/article25585274.ece?_escaped_fragment_=

[bushstory61-blog]

Nestlé’s new Ireland R&D centre to focus on infant nutrition

The Limerick-based €27m manufacturing facility marks the culmination of a three-year building project in which forty research staff are now employed at the research facility.

“Our Irish R&D Centre will benefit from Nestlé’s global R&D network and help to position Nestlé at the fore of infant and maternal nutritional product development, one of Nestlé’s most important growth drivers,”​ said Thomas Hauser, head of global product and technology development for Nestlé.

“With this new centre, we will increase the pace of our innovation capacity by enabling our scientists to explore innovative nutritional solutions for the crucial first 1,000 days of life.”​

Along with Danone, Mead Johnson (now RB), Abbott, FrieslandCampina, and Heinz, these firms represent the six main infant-formula manufacturers in Europe, heading up an industry worth €41bn in 2015.

According to Euromonitor International, the sector is predicted to increase by around 50% in the next three years. Currently, the Swiss-based giants are the world’s biggest infant formula maker, with around a 21% share of the market.

The market research analysts also place Nestlé number one in China, which accounts for a third of a global market worth $68bn.

Co-located with Wyeth Nutrition​

The R&D Centre is co-located with Nestlé’s Wyeth Nutrition manufacturing plant. Wyeth Nutrition’s Infant Formula business, which Nestle acquired back in 2012, produces a range of premium milk powder products for infants, young children and mothers for export to world markets.

In a press release, Nestlé said the R&D Centre would concentrate on “developing premium, science-based products for mothers and infants. ​

“It incorporates state-of-the-art laboratory facilities as well as a full pilot-scale manufacturing line to facilitate the development, and testing of new products from initial concept through to product deployment. The project investment was supported by Enterprise Ireland,” ​the statement added.

“Michael Creed, minister for agriculture, food and the marine, added, “This is a strategically important investment for Ireland by the world’s largest food and beverage company.​

“Nestlé’s decision to invest and open this centre further places Ireland internationally as a location that offers quality raw dairy materials combined with a highly educated and skilled workforce. It is a major signal of confidence in the future and quality of the Irish dairy industry.”​

Infant formula business ‘highly profitable’​

The investment comes as Nestlé looks to reorganise its infant nutrition unit to compete with regional rivals and boost sales.

Speaking to Reuters​​ back in 2017, the firm said it would hire regional managers for the €8.8bn ($10bn) business to respond to regional trends faster.

The switch in strategy comes five months after Nestlé's new CEO identified its highly profitable infant formula business as a priority.

“The new organisation will allow Nestlé's infant nutrition business to deliver accelerated organic growth and realise further efficiency gains,”​ Nestlé said, adding it would allow it to be more “agile and efficient”​ in responding to local demands.

Source: https://www.nutraingredients.com/Article/2019/01/21/Nestle-s-new-Ireland-R-D-centre-to-focus-on-infant-nutrition