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Derin, we are on Tumblr.

There will be a legion of gods soon enough.

How can you doubt?

On the other hand, I doubt that would work to ward you away.

You can offer them your Totally Normal Spaceship and convert them.

Your very own gods.

HELLO?????

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Emperor: Do you know your weakness?

Female lead: *overthinking, because politics are complex*

Emperor: LOL. It's not THAT deep! STAMINA! You lack STAMINA! Take up a sport!

FL: *relieved* Thank you for the insight.

- FL and her knight about to leave -

Emperor to her personal knight: YOU.

- This a cliff. Welcome to the cliff! -

On one hand. I totally agree with a commmenter saying "i forgot the emperor is an ass". Because yeah, but it's not like the guy is stupid. He could not have stayed an emperor if he was stupid.

On another hand. The context: Lack of stamina conversation.

From the context and accounting for in-story world building - OMG, I'm about to loose my mind.

THE EMPEROR is about to talk to THE KNIGHT about BEDSPORT??

I need a drink.

And a snack.

I could be wrong. I could be right.

Next chapter's gonna be wild, huh.

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(x)

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K-Pop Demon Hunters + music 🎶

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"A cure for HIV could be a step closer after researchers found a new way to force the virus out of hiding inside human cells.

The virus’s ability to conceal itself inside certain white blood cells has been one of the main challenges for scientists looking for a cure. It means there is a reservoir of the HIV in the body, capable of reactivation, that neither the immune system nor drugs can tackle.

Now researchers from the Peter Doherty Institute for Infection and Immunity in Melbourne, have demonstrated a way to make the virus visible, paving the way to fully clear it from the body.

It is based on mRNA technology, which came to prominence during the Covid-19 pandemic when it was used in vaccines made by Moderna and Pfizer/BioNTech.

In a paper published in Nature Communications, the researchers have shown for the first time that mRNA can be delivered into the cells where HIV is hiding, by encasing it in a tiny, specially formulated fat bubble. The mRNA then instructs the cells to reveal the virus.

Globally, there are almost 40 million people living with HIV, who must take medication for the rest of their lives in order to suppress the virus and ensure they do not develop symptoms or transmit it. For many it remains deadly, with UNAids figures suggesting one person died of HIV every minute in 2023.

It was “previously thought impossible” to deliver mRNA to the type of white blood cell that is home to HIV, said Dr Paula Cevaal, research fellow at the Doherty Institute and co-first author of the study, because those cells did not take up the fat bubbles, or lipid nanoparticles (LNPs), used to carry it.

The team have developed a new type of LNP that those cells will accept, known as LNP X. She said: “Our hope is that this new nanoparticle design could be a new pathway to an HIV cure.”

When a colleague first presented test results at the lab’s weekly meeting, Cevaal said, they seemed too good to be true.

“We sent her back into the lab to repeat it, and she came back the next week with results that were equally good. So we had to believe it. And of course, since then, we’ve repeated it many, many, many more times.

“We were overwhelmed by how [much of a] night and day difference it was – from not working before, and then all of a sudden it was working. And all of us were just sitting gasping like, ‘wow’.”

Further research will be needed to determine whether revealing the virus is enough to allow the body’s immune system to deal with it, or whether the technology will need to be combined with other therapies to eliminate HIV from the body.

The study is laboratory based and was carried out in cells donated by HIV patients. The path to using the technology as part of a cure for patients is long, and would require successful tests in animals followed by safety trials in humans, likely to take years, before efficacy trials could even begin.

“In the field of biomedicine, many things eventually don’t make it into the clinic – that is the unfortunate truth; I don’t want to paint a prettier picture than what is the reality,” stressed Cevaal. “But in terms of specifically the field of HIV cure, we have never seen anything close to as good as what we are seeing, in terms of how well we are able to reveal this virus.

“So from that point of view, we’re very hopeful that we are also able to see this type of response in an animal, and that we could eventually do this in humans.”

Dr Michael Roche of the University of Melbourne and co-senior author of the research, said the discovery could have broader implications beyond HIV, with the relevant white blood cells also involved in other diseases including cancers.

Dr Jonathan Stoye, a retrovirologist and emeritus scientist at the Francis Crick Institute, who was not involved in the study, said the approach taken by the Melbourne team appeared be a major advance on existing strategies to force the virus out of hiding, but further studies would be needed to determine how best to kill it after that.

He added: “Ultimately, one big unknown remains. Do you need to eliminate the entire reservoir for success or just the major part? If just 10% of the latent reservoir survives will that be sufficient to seed new infection? Only time will tell.

“However, that does not detract from the significance of the current study, which represents a major potential advance in delivery of mRNA for therapeutic purposes to blood cells.”"

-via The Guardian, June 5, 2025

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Nosferatu mug set.

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lets be exhausted on mama

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Sucks to see someone else living your dream.

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"Well, you SHOULD approve this information. It's easy - you deal with finance every day."

No, actually.

I'm not qualified to do ANYTHING about a financial audit, except to pass on the audit docs to the financial department WHOSE JOB IT IS TO DEAL WITH FINANCIAL AUDIT INQUIRIES.

FINANCE is literally NOT MY JOB.

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I was more or less stunned by what had happened. I had been prepared for criticism and ridicule - I was accustomed to them. But it had never occurred to me that people might want to hound and persecute me for my change in role. I had lived as a woman because that was my social standing, and had been made fun of and called 'half-man', and now when I had faced the situation and righted the grotesquely false position in which I had lived so long, it seemed that the public would damn me because I had once, perforce [by force, by necessity], worn skirts. I tried to get other hospital work. I went to the men who had been my chiefs and told them the truth and asked their aid in securing another position; to a man they turned me down. I tried to get other sorts of work and failed tor the same reason as soon as I gave my name. Then my family employed counsel and instituted proceedings to have my name legally changed; and the medical school from which I had been graduated served notice on us that if we persisted they would rescind my diploma and have me disbarred from practice.

— excerpt from Letter from Alan Hart to Mary Roberts Rinehart, August 3, 1921, on the subject of his transition from female to male and the impact of being publicly outed by a woman who recognized him. Alan Hart was one of the first men to get a hysterectomy in the US, and pioneered the use of X-rays in the diagnosis of tuberculosis, which ended up being crucial to treatment as the disease was asymptomatic early on.

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someone got really mad at me for being pro-pornography so i'd like to be annoying for a little longer:

-there are enormous problems with exploitation in the porn industry that harm and endanger the people within it, and that harm is carried out mostly against women and minorities

-this is Bad

-however the last century of passing laws against pornography hasn't actually helped any of those problems, and what sex workers tend to advocate for is the legitimization of their labor, so that they can then access the same protections and regulations that people in other industries can access

-for instance football players, miners, roofers, and warehouse workers are also exploited and endangered by their professions, have to work long hours, and can end up traumatized and disabled by unregulated and unsafe working conditions. these people are used up and thrown away by powerful bosses they can't individually challenge.

-however because these industries are not de facto illegal to participate in, when these people form unions and demand better working conditions, they can at least fight for their rights.

-sex workers, who engage in heavily stigmatized work that's also often illegal, have little recourse to demand better treatment.

-even if you don't like porn, and especially if you don't like porn, if you care about the women who are exploited in pornography, you need to advocate for the legality of pornography.

-the more illegal the porn industry is, the less safe and fair it is, and people will still be working in it, no matter how illegal it is.

-again: the porn industry should be regulated like any other industry and subject to laws guaranteeing fair compensation for labor, safe working conditions, and legal resources for workers suffering exploitation and abuse.

-once it is legal to do sex work, then women can bring charges against the men who have broken their contracts and abused them.

-and that is why i push back against posts saying that pornography is evil. it is an entertainment product, made by people, to meet an ongoing demand. criminalizing the consumption and production of it may slightly lessen the demand at the incredible cost of endangering everyone involved. and i think that is what's evil.

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just one of those things that makes me so irrationally angry despite how pointless it is to get worked up about 

ps i’ve just started playing ultra sun and guess who i have on my team

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Drop Dead Gorgeous 1999 | dir. Michael Patrick Jann

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Weird when you first start paying attention to animal noises and realize they don't actually sound like the words we use