#Accelerometer Overdose
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12:43 AM EDT April 18, 2025:
Working Men's Club - "Accelerometer Overdose" From the album Mojo Presents Handle With Care: New Music 2022 (January 2022)
Last song scrobbled from iTunes at Last.fm
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Electronic pill monitors your breathing and heart rate from your gut
Thanks ; Alice Klein Published ; Nov,22 The device contains an accelerometer that measures breathing and heart rate by detecting vibrations in the gut A smart pill that can measure your breathing and heart rate from inside your gut could potentially diagnose sleep apnoea and even detect opioid overdoses. Sleep apnoea is defined as lapses in breathing during sleep. Diagnosis usually involves…

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Binker & Moses Album Review: Feeding the Machine

(Gearbox)
BY JORDAN MAINZER
It may be time to strip the “honorary” part of Max Luthert’s “honorary third member” title when it comes to Binker & Moses. For their new album Feeding the Machine, the saxophone and drums duo of Binker Golding and Moses Boyd brought their live partner to the studio to add tape loops and electronics to the ingredient list. The result is a major sonic shift, feeding their improvisations through machines, Luthert’s modular synthesis reordering acoustic tracks and drums in a way that’s so distorted it doesn’t even sound acoustic. From the opening moments of “Asynchronous Intervals”, though you recognize Golding’s saxophone, echoing loops clue you into the sea change. This is different, and it’s here to stay.
In essence, Luthert allows Golding and Boyd to do what they’ve always done well--play with volume and tempo and off of each other, with both dexterity and soul--while amplifying new timbres and moods. Their tracks have always been able to be tempered pieces or instantaneously frenetic, and now they have new dimensions. Luthert’s electronics make chaotic flares and subtle grooves sound like they’re being sucked into cyberspace and spat out back on the urgent “Active-Multiple-Fetish-Overlord”. On epics like “Asynchronous Intervals” and “Accelerometer Overdose”, neither of which would be totally out of place composition-wise on previous albums, they provide undercurrents of mood and nature. At the same time, when Luthert takes a step back, Golding and Boyd seem extra forceful by comparison. Boyd especially stands out with meaty hip hop and funk beats; on “Accelerometer Overdose”, he provides the bed for Golding’s polyrhythmic saxophone, looped and distorted lines that sound like everything from harmonium to funk keyboards. At the end, his pitch-shifted horn cuts in and out like a sneaky housefly that keeps buzzing close to your ears.
The album’s back half is novel in the context of Binker & Moses, especially because they embrace the drone aspects of Luthert’s electronics. “Feed Infinite” is minimal, beginning with a wobbly whirr before Golding and Boyd come in, light as feathers. As the song progresses, Golding is consistently expressive, but not overpowering, while Boyd shows off a funk beat with impressive drum fills, and Luthert adds a synth line that wouldn’t sound out of place on Sound of Silver. Similar dreamy hues kickstart the appropriately titled “After The Machine Settles”. As saxophone and drums glitch and disappear, Golding eventually reenters and overpowers the cut-up electronics, he and Boyd clearing Luther’s hazy spiderwebs of noise. And if Boyd shows off his rock chops throughout, closer “Because Because” is a showcase for Golding, his foreboding faraway tenor crisscrossing with funereal soprano. Boyd’s rustling brushwork gives the song a breezy sway for a while, until Golding’s saxophone multiplies seemingly exponentially. The machine has been fed, but the album ends with someone in the studio shouting, “Yup!” satisfied with their statement of mastery.
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#album review#binker & moses#feeding the machine#gearbox#gearbox records#binker and moses#binker golding#moses boyd#max luthert#sound of silver
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How could the HEV perform a diagnostic test of the user to apply medical attention? Using sensors?
Yes, the HEV could perform diagnostic testing of the user with a variety of sensors. In my version of the HEV suit, the sensors and associated health monitoring accessories would be:
“Atmospheric contaminant sensors”
· Sensor for radiation (Geiger counter)
· Sensor for chemical waste
· Sensor for biohazards
· Sensor for acid/corrosive chemicals
· Sensor for heat damage
· Sensor for cold damage
“Vital Signs Monitoring”
· Sensor for electric damage
· Sensor for blood toxins
· Major and minor lacerations detection
· Major and minor fracture detection
· O2 Meter
· Heart Rate
· Blood Pressure (Blood loss and internal bleeding detection)
· Electronics associated with morphine injection mechanism
(Yes, this list is a little longer and differently organized than the one in the first Anatomy of a HEV suit because I’ve double checked a few things and found I was missing a few! By the way, here’s a short video that I thought was relevant: https://www.youtube.com/watch?v=6oPGjA5-4AM. It covers how the HEV handles status and damage conditions in the gameplay of the original Half-Life.)
Instead of having a single diagnostic test, the HEV would constantly monitor the readings from each of its sensors. Should the sensor detect something that falls outside of the threshold of ‘normal’ health, the HEV would then apply the appropriate medical treatment.
More under the cut:
In the case of the electrical, heat, cold, radiation, chemical waste, and biohazard status condition sensors listed, multiple of each kind of sensor would be placed on the outside of the HEV. If the sensors sense a level of radiation/chemicals/biological contaminants that exceeds a set amount, or exposure to electric shock or extreme heat/cold, they would signal the HEV, and the HEV would flash the appropriate status icon to the wearer (in-game the icon shows up on the lower left hand of the screen, but to the wearer it would be on the HUD (Heads Up Display) on the helmet), verbally alert the user of exposure to the substance, and potentially attempt an appropriate treatment based on the situation.
For the blood toxin sensor – there only needs to be one of those, and it would be inside the HEV, with a port into a vein (In my version of the HEV, it would likely be connected somewhere in or around the morphine injection mechanism’s port). Again, if the sensor senses that one or more toxic chemicals has risen above a certain concentration in the blood, it would signal the HEV, which would register that there are toxins in the blood, verbally alert the user, and potentially take immediate medical action.
As for major and minor laceration detection, and major and minor fracture detection, the HEV doesn’t have the opportunity of direct sensing and must infer the state of the user through the data it detects.
To detect lacerations (cuts, scratches, gashes), just off the top of my head, the suit could potentially use a web or mesh of interwoven sensors woven into or in between one of its lower layers. Should the sensor mesh be broken in an area (by a slash or other wound), the loss of a signal in the area would indicate the suit has been breached and the skin has probably been broken. It’s not 100% going to be accurate –there’s always the tiny possibility of the sensor mesh being broken, yet the wearer underneath being miraculously unharmed – but if it’s strong enough to break through all the HEV layers it probably slashed through the wearer too. However, this mesh layer would lose accuracy over time as it gets more and more slashed, so I would have to look a little deeper into the topic of laceration detection before designating a mesh of sensors as the go-to method of detecting cuts/gashes/slashes.
As for fractures (broken bones), it would likely again be more of an inference. There isn’t a way to directly detect fractures outside of X-rays, and an internal X-ray machine is out of the question. The HEV is supposed to prevent you from getting exposed to radiation, not expose you to more of it! So, instead, the HEV would have multiple accelerometers (which measure the speed something is accelerating in) in several orientations and locations, as well as force sensors (to sense if the suit got hit by a force), and potentially gyroscopes (for orientation), would be placed all over the HEV.
Should the HEV detect a force greater than a certain limit on a body part, it would assume that the wearer got a fracture there. For example, if somebody throws a bowling ball at the wearer, once the wearer was hit, the suit would detect the force of the bowling ball hitting the wearer and the location it was hit at, and determine if the force would have broken a bone there.
Alternately, should some part of the wearer suddenly accelerate and then stop suddenly it could also infer that the wearer has probably broken their bones. For example, is the wearer falls from a tower, the suit would measure sudden acceleration, then would detect the force on the suit and sudden deceleration when the wearer hits the ground and infer that the wearer got a fracture and the location of the fracture.
The O2 meter detects remaining oxygen available to the user and alerts the user of the amount left. The HEV does not have a visible oxygen tank, and the wearer does not tend to last long underwater, so it may just be measuring the amount of oxygen circulating within the suit as the wearer breathes in and out the same air. (The HEV could potentially be refreshing/recycling the air with chemical means, but I would have to look more into that.)
Heart rate sensors, of course, detect heart rate. Blood pressure sensors (think blood pressure cuffs), of course, measure blood pressure. These sensors would constantly monitor heart rate and blood pressure and help the suit determine if overall vitals are dropping –obviously, if the wearer flatlines, that’s bad, but even things like erratic heart rate could indicate issues. A sudden drop in blood pressure (especially associated with detection of a sudden force/slash/acceleration) likely indicates to the suit that the wearer has lost a significant amount of blood (both external and internal blood loss will decrease blood pressure), so should the blood pressure sensor sense that, it would alert the suit, which would trigger the suit to verbally alert the user of blood loss and (potentially, in light of the compression suit in my version of the HEV suit) activate compression at an area where the force/slash/acceleration was registered at.
Lastly, the electronics associated with the morphine injection mechanism would be necessary to determine whether or not to inject morphine into the wearer, and the time of last injection (to prevent overdose – if the wearer gets badly hurt a bunch of times in 10 minutes, there’s no point in injecting them with morphine every time they got an injury!).
#courts talks#anatomy of a hev suit#this one ended up kind of long haha#the next couple of answers shouldn't be this long but No Guarantees Since I Like To Ramble
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Album Of The Week: Binker & Moses – Feeding The Machine (Gearbox Records)
Across the LP, the sax & drum duo fuse ambient, minimalist, and experimental electronic music on this new project to form a more futuristic sound. The album features Max Luthert on tape loops and electronics.
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“While Golding still soliloquises with familiar brio, and scene linchpin Boyd ranges from susurrations to swinging breakbeats, especially on the banging Accelerometer Overdose, Luthert contributes an insistent electronic presence throughout, made up of Golding and Boyd’s output manipulated into drones, whirrs and textures.”
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Binker and Moses - Accelerometer Overdose - from Feeding The Machine
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Neuromodulation: Using the brain’s internal language to relieve pain
When a patient walks into Dr. Jason Yong’s clinic at Brigham & Women‘s Faulkner Hospital complaining of pain, his work has just begun.
“Pain is a common symptom and it’s totally generic,” Yong explained to MassDevice. “The other thing that makes it challenging is that it’s so subjective.”
After Yong exhausts the pharmaceutical possibilities for managing his patient’s pain, he turns to technological options such as implantable neuromodulation systems.
Neuromod devices use electrodes to deliver stimulation directly to a patient’s brain, spinal cord or peripheral nerves, inhibiting pain signals or triggering neural impulses. Although commonly associated with managing pain relief, neuromod systems are used to treat an array of conditions, including Parkinson’s disease, incontinence and vascular disease.
“This is a defining moment in neuroscience: for the first time, we are using the ‘language’ of the nervous system to alter its responses. We can now pinpoint pain signals and deliver personalized therapy,” the medical director for Abbott’s neuromod business, Dr. Allen Burton, said in a statement.
The global market’s appetite for these systems shows no signs of slowing down – it’s expected to grow from $8.4 billion last year to $13.3 billion in 2022, according to Neurotech Reports.
The perspective from one industry leader Keith Boettiger, president of Abbott‘s (NYSE:ABT) neuromod division, has been working in the space since 2004. A lot has changed since then, he told us.
“I’ve been in this space for 14 years and in the first 10 years of my career, we really only saw incremental innovation related to hardware or devices, such as increasing the number of electrodes on leads or adding components such as accelerometers and MRI compability,” Boettiger said. “All these things are interesting and can take the technology forward, but none of them had clinical data to support their use and none of these advancements were specifically designed with the patient in mind.
“It was really more about being competitive in the market in the doctors’ eyes versus actually creating better efficacy long-term for the patients with these devices,” he added.
Abbott, which has a number of FDA-approved neuromod systems on the market, decided to rethink how it went about creating these products.
“We sat down in 2013 and we changed our philosophy of how we were going to develop products and we took really this people-centered, patient-centric philosophy around development,” Boettiger said.
As an example, Boettiger pointed toward rechargeable neuromod systems, which were all the rage in the mid-2000’s.
“People sunk a lot of money into rechargeable devices because everybody thought that the longer the battery lasts in the patient, the better. That was the philosophy, but there was no data to support that,” he said. “That was driven by physicians saying, ‘I don’t want to have to manage patients needing a device replacement, so the longer the battery can conceivably last, the better.'”
After surveying the market and studying outcomes, Abbott discovered that the rechargeable systems were being removed from patients at twice the rate as their non-rechargeable counterparts.
So the company moved to a recharge-free platform for its neuromod systems. Abbott was aiming to develop a system that would require minimal interaction, similar to a cardiac pacemaker.
“We drew the conclusion that these devices are going to be better for patients if we’re not drawing attention to their device every day by having them recharge, by giving them a medical grade patient programmer that they pull out of their purse or they pull it out of their pocket and people are staring at them and trying to figure out what’s wrong with them,” Boettiger said. “What was better for the patient was to receive a system they never had to recharge, that would last for years, and that managed their pain in a way they rarely had to think about.”
From a doctor’s point-of-view To treat his patients’ pain, Yong uses what he calls a “step-wise approach.” First, he will try pharmaceutical interventions, like non-steroidal anti-inflammatories, even if medicines haven’t helped in the past for a particular patient.
“As we exhaust all these other steps, we may start to think about the implantable devices. We don’t like to implant a device in someone if we can avoid it, so we will exhaust every single step,” he said.
“I think the biggest part of our job is expectation management. So I tell them that, ‘Listen, we’re not going to get you to zero. We’re looking to reduce [the pain] by 50% at least, and make you more functional.’ So that’s our primary objective, is to make you more functional, to get you through this, not to take away your pain, just to reduce it and manage it.”
After a patient has qualified for an implantable device to manage their pain, Yong takes them on a trial run with the system for seven days. More than 80% of people who try neuromodulation experience a reduction of pain worthy of a more permanent implant at his clinic.
“For the patients that we are able to help, they are very happy with it,” he said.
For some patients, the pain relief they experience during the trial run is not enough to justify the risks of the implant procedure.
“You get the patients that are like, ‘I feel 30% better. I want it in,’ and you have to tell them no. That’s a difficult conversation to have with them,” Yong said.
Tackling the opioid crisis The history of pain management in the U.S. is complicated and nothing has made that more clear than the staggering statistics linked to the opioid crisis. More than 115 people die every day from opioid overdoses, according to the Centers for Disease Control & Prevention.
Both Abbott and Yong see neuromodulation as one way to help get the crisis under control. In January of 2017, Abbott touted data from a 5,400-patient study evaluating daily opioid use following spinal cord stimulation therapy in people with chronic pain. The researchers found that average daily opioid use declined or remained steady in people with a spinal cord stim device. People who had the device removed experienced greater opioid use over time.
“We’re seeing that it’s moving the needle on reducing the overall doses of the opioids on these patients. Not many patients. We do have some patients with the neuromodulation systems, but not many, where they will come completely off. But if you’re able to reduce it quite a bit, then that has a big impact on the epidemic as well,” Yong said. “So, I do see neuromodulation as helping to reduce the overall burden of opioids in society for these people who are these complicated, refractory patients. I’m not saying that this is the answer to the opioid epidemic, but I’m saying it’s part of the answer for part of the problem.”
Ryan Lakin, Divisional VP of R&D with Abbott’s neuromod unit, agreed.
“People living with chronic pain are now more than ever able to resume normal and healthier lives thanks to neuromodulation systems using Apple iOS, Bluetooth connectivity and familiar consumer tech. These non-opioid treatments allow people to better manage their disease and focus on living full lives, pain free,” he said in an emailed statement.
Looking ahead Compared to his early days within the industry, Boettiger predicted that Abbott will continue to rely more heavily on long-term clinical data and the patient perspective to support its product development efforts.
“I think the appetite now is much higher for clinical evidence, not only for clinicians and patients but for payers. For these devices and for this space to be successful long-term, you’re going to have to invest in the clinical research to support the innovation that you’re doing,” he said.
Yong said he also wants to see more rigorous clinical studies for implantable neuromod devices but added that those studies should be independent of the companies creating the products.
“In an ideal world, I think we should be taking the funding out of the device company’s burden and putting it under some other funding source that’s a little bit more objective. I think it’s a problem inherently in research that there is bias based off of what the funding source is,” said Yong, who reported no conflicts of interest with Abbott.
“Right now it’s really tough to get that kind of funding because it’s so expensive to run these trials. Especially when we’re talking about an implantable device. So I don’t think that’s a reasonable or realistic way to do it, but in an ideal world, that’s what we would be doing, is doing a completely unbiased design of these studies,” he said.
It would be helpful to have a registry of all the outcomes associated with implantable neuromod devices, Yong added. Observing patients in his own clinic, he’s seen the tangible relief delivered by updated neuromod systems.
“With some of the newer systems, we’re seeing more robust and durable relief and we think maybe that’s because of what we’ve learned from previous patients,” Yong said. “It’s an exciting time to be in neuromodulation.”
The post Neuromodulation: Using the brain’s internal language to relieve pain appeared first on MassDevice.
from MassDevice http://bit.ly/2TRUfVs
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9:37 PM EDT April 21, 2025:
Working Men's Club - "Accelerometer Overdose" From the album Mojo Presents Handle With Care: New Music 2022 (January 2022)
Last song scrobbled from iTunes at Last.fm
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9:50 AM EDT April 1, 2025:
Working Men's Club - "Accelerometer Overdose" From the album Mojo Presents Handle With Care: New Music 2022 (January 2022)
Last song scrobbled from iTunes at Last.fm
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1:40 AM EDT September 25, 2024:
Working Men's Club - "Accelerometer Overdose" From the album Mojo Presents Handle With Care: New Music 2022 (January 2022)
Last song scrobbled from iTunes at Last.fm
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